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Tytuł:
Home medication management problems and associated factors among psychiatric patients using home care pharmacy services at government hospitals in western Malaysia.
Autorzy:
Lau CLL; Pharmacy Department, Bahagia Ulu Kinta Hospital, Ministry of Health Malaysia, Jalan Besar, 31250, Tanjung Rambutan, Perak, Malaysia. .
Hor CY; Pharmacy Department, Seri Manjung Hospital, Ministry of Health Malaysia, Seri Manjung, Perak, Malaysia.
Ong ST; Pharmacy Department, Teluk Intan Hospital, Ministry of Health Malaysia, Teluk Intan, Perak, Malaysia.
Roslan MF; Pharmacy Department, Raja Permaisuri Bainun Hospital, Ministry of Health Malaysia, Ipoh, Perak, Malaysia.
Beh XY; Pharmacy Department, Taiping Hospital, Ministry of Health Malaysia, Taiping, Perak, Malaysia.
Permal D; Pharmacy Department, Slim River Hospital, Ministry of Health Malaysia, Slim River, Perak, Malaysia.
Rama S; Pharmacy Department, Raja Permaisuri Bainun Hospital, Ministry of Health Malaysia, Ipoh, Perak, Malaysia.
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Źródło:
BMC health services research [BMC Health Serv Res] 2022 Jun 01; Vol. 22 (1), pp. 726. Date of Electronic Publication: 2022 Jun 01.
Typ publikacji:
Journal Article; Multicenter Study
MeSH Terms:
Home Care Services*
Medication Therapy Management*
Cross-Sectional Studies ; Government ; Hospitals ; Humans ; Malaysia/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Imaging Kv1.3 Expressing Memory T Cells as a Marker of Immunotherapy Response.
Autorzy:
Goggi JL; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore.
Khanapur S; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Ramasamy B; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Hartimath SV; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Rong TJ; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Cheng P; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Tan YX; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Yeo XY; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Jung S; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore.; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Goay SSM; LKCMedicine-ICESing Ion Channel Platform, Lee Kong Chian School of Medicine, Nanyang Technological University, 59 Nanyang Drive, Singapore 636921, Singapore.
Ong ST; LKCMedicine-ICESing Ion Channel Platform, Lee Kong Chian School of Medicine, Nanyang Technological University, 59 Nanyang Drive, Singapore 636921, Singapore.
Hwang YY; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
Chandy KG; LKCMedicine-ICESing Ion Channel Platform, Lee Kong Chian School of Medicine, Nanyang Technological University, 59 Nanyang Drive, Singapore 636921, Singapore.
Robins EG; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.; Clinical Imaging Research Centre (CIRC), Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, #B1-01, Singapore 117599, Singapore.
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Źródło:
Cancers [Cancers (Basel)] 2022 Feb 26; Vol. 14 (5). Date of Electronic Publication: 2022 Feb 26.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
THZ531 Induces a State of BRCAness in Multiple Myeloma Cells: Synthetic Lethality with Combination Treatment of THZ 531 with DNA Repair Inhibitors.
Autorzy:
Shyamsunder P; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.; Cancer & Stem Cell Biology Programme, Duke-NUS Medical School, Singapore 169857, Singapore.
Sridharan SP; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Madan V; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Dakle P; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Zeya C; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Kanojia D; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Chng WJ; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.; Department of Hematology-Oncology, National University Cancer Institute of Singapore (NCIS), National University Hospital, Singapore 119074, Singapore.
Ong ST; Cancer & Stem Cell Biology Programme, Duke-NUS Medical School, Singapore 169857, Singapore.; Department of Haematology, Singapore General Hospital, Singapore 169608, Singapore.; Department of Medical Oncology, National Cancer Centre, Singapore 169610, Singapore.; Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
Koeffler HP; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.; Department of Hematology-Oncology, National University Cancer Institute of Singapore (NCIS), National University Hospital, Singapore 119074, Singapore.; Cedars-Sinai Medical Center, Division of Hematology/Oncology, UCLA School of Medicine, Los Angeles, CA 90095, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 21; Vol. 23 (3). Date of Electronic Publication: 2022 Jan 21.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Repair*
Synthetic Lethal Mutations*
Anilides/*pharmacology
Biomarkers, Tumor/*genetics
Gene Expression Regulation, Neoplastic/*drug effects
Multiple Myeloma/*drug therapy
Poly(ADP-ribose) Polymerase Inhibitors/*pharmacology
Pyrimidines/*pharmacology
Animals ; Apoptosis ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Cell Proliferation ; Drug Therapy, Combination ; Humans ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Multiple Myeloma/genetics ; Multiple Myeloma/pathology ; Prognosis ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
BIM deletion polymorphism profiling complements prognostic values of risk scores in imatinib-treated Asian chronic myeloid leukemia patients.
Autorzy:
Than H; a Department of Hematology , Singapore General Hospital , Singapore , Singapore.
Lye WK; b Centre for Quantitative Medicine , Duke-NUS Medical School Singapore , Singapore , Singapore.
Sng C; a Department of Hematology , Singapore General Hospital , Singapore , Singapore.
Allen JC Jr; b Centre for Quantitative Medicine , Duke-NUS Medical School Singapore , Singapore , Singapore.
Ong ST; a Department of Hematology , Singapore General Hospital , Singapore , Singapore.; c Program for Cancer and Stem Cell Biology , Duke-NUS Medical School Singapore , Singapore , Singapore.; d Department of Medical Oncology , National Cancer Center Singapore , Singapore , Singapore.; e Department of Medicine , Duke University Medical Center , Durham , NC , USA.
Chuah C; a Department of Hematology , Singapore General Hospital , Singapore , Singapore.; c Program for Cancer and Stem Cell Biology , Duke-NUS Medical School Singapore , Singapore , Singapore.
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2019 Jan; Vol. 60 (1), pp. 234-237. Date of Electronic Publication: 2018 Jun 19.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms:
Antineoplastic Agents/*therapeutic use
Bcl-2-Like Protein 11/*genetics
Biomarkers, Tumor/*genetics
Imatinib Mesylate/*therapeutic use
Leukemia, Myeloid, Chronic-Phase/*drug therapy
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Asian People/genetics ; Female ; Humans ; Kaplan-Meier Estimate ; Leukemia, Myeloid, Chronic-Phase/genetics ; Leukemia, Myeloid, Chronic-Phase/mortality ; Male ; Middle Aged ; Polymorphism, Genetic ; Predictive Value of Tests ; Prognosis ; Sequence Deletion ; Treatment Outcome ; Young Adult
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target.
Autorzy:
Ng KP; Cancer and Stem Cell Biology Signature Research Program, Duke-NUS Medical School, Singapore, Singapore.
Manjeri A; Cancer and Stem Cell Biology Signature Research Program, Duke-NUS Medical School, Singapore, Singapore.
Lee LM; Cancer and Stem Cell Biology Signature Research Program, Duke-NUS Medical School, Singapore, Singapore.
Chan ZE; Cancer and Stem Cell Biology Signature Research Program, Duke-NUS Medical School, Singapore, Singapore.
Tan CY; Cancer and Stem Cell Biology Signature Research Program, Duke-NUS Medical School, Singapore, Singapore.
Tan QD; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Majeed A; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Lee KL; Cancer and Stem Cell Biology Signature Research Program, Duke-NUS Medical School, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Chuah C; Cancer and Stem Cell Biology Signature Research Program, Duke-NUS Medical School, Singapore, Singapore.; Department of Haematology, Singapore General Hospital, Singapore, Singapore.
Suda T; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; International Research Center for Medical Sciences, Kumamoto University, Japan.
Ong ST; Cancer and Stem Cell Biology Signature Research Program, Duke-NUS Medical School, Singapore, Singapore.; Department of Haematology, Singapore General Hospital, Singapore, Singapore.; Department of Medical Oncology, National Cancer Centre, Singapore, Singapore.; Department of Medicine, Duke University Medical Center, Durham, NC, United States of America.
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Źródło:
PloS one [PLoS One] 2018 Oct 11; Vol. 13 (10), pp. e0205254. Date of Electronic Publication: 2018 Oct 11 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Arginase/*antagonists & inhibitors
Arginine/*analogs & derivatives
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
Antineoplastic Agents/therapeutic use ; Arginase/genetics ; Arginase/metabolism ; Arginine/pharmacology ; Arginine/therapeutic use ; CRISPR-Cas Systems/genetics ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Enzyme Assays ; Feasibility Studies ; Gene Knockout Techniques ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology ; Primary Cell Culture ; RNA, Small Interfering/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The HDAC inhibitor SB939 overcomes resistance to BCR-ABL kinase Inhibitors conferred by the BIM deletion polymorphism in chronic myeloid leukemia.
Autorzy:
Rauzan M; Cancer and Stem Cell Biology Signature Research Programme, Duke-NUS Medical School, Singapore.
Chuah CT; Cancer and Stem Cell Biology Signature Research Programme, Duke-NUS Medical School, Singapore.; Department of Haematology, Singapore General Hospital, Singapore.
Ko TK; Cancer and Stem Cell Biology Signature Research Programme, Duke-NUS Medical School, Singapore.
Ong ST; Cancer and Stem Cell Biology Signature Research Programme, Duke-NUS Medical School, Singapore.; Department of Haematology, Singapore General Hospital, Singapore.; Department of Medical Oncology, National Cancer Centre Singapore, Singapore.; Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America.
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Źródło:
PloS one [PLoS One] 2017 Mar 16; Vol. 12 (3), pp. e0174107. Date of Electronic Publication: 2017 Mar 16 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Gene Deletion*
Antineoplastic Agents/*pharmacology
Bcl-2-Like Protein 11/*genetics
Benzimidazoles/*pharmacology
Enzyme Inhibitors/*pharmacology
Fusion Proteins, bcr-abl/*antagonists & inhibitors
Histone Deacetylase Inhibitors/*pharmacology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*genetics
Apoptosis/drug effects ; Humans ; K562 Cells ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology ; RNA Splicing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
GapmeR cellular internalization by macropinocytosis induces sequence-specific gene silencing in human primary T-cells.
Autorzy:
Fazil MH; Lymphocyte Signalling Research Laboratory, Lee Kong Chian School of Medicine, Nanyang Technological University, 636921, Singapore.
Ong ST; Lymphocyte Signalling Research Laboratory, Lee Kong Chian School of Medicine, Nanyang Technological University, 636921, Singapore.
Chalasani ML; Lymphocyte Signalling Research Laboratory, Lee Kong Chian School of Medicine, Nanyang Technological University, 636921, Singapore.
Low JH; Lymphocyte Signalling Research Laboratory, Lee Kong Chian School of Medicine, Nanyang Technological University, 636921, Singapore.
Kizhakeyil A; Lymphocyte Signalling Research Laboratory, Lee Kong Chian School of Medicine, Nanyang Technological University, 636921, Singapore.
Mamidi A; Lymphocyte Signalling Research Laboratory, Lee Kong Chian School of Medicine, Nanyang Technological University, 636921, Singapore.; School of Chemical and Biomedical Engineering, Nanyang Technological University, 637459, Singapore.
Lim CF; School of Biological Sciences, Nanyang Technological University, 637551, Singapore.
Wright GD; Institute of Medical Biology, A*STAR, Immunos, Biopolis, 138648, Singapore.
Lakshminarayanan R; Singapore Eye Research Institute, The Academia, 20 College Road, 169856, Singapore.
Kelleher D; Lymphocyte Signalling Research Laboratory, Lee Kong Chian School of Medicine, Nanyang Technological University, 636921, Singapore.; Faculty of Medicine, University of British Columbia, Vancouver, British Columbia V1Y 1T3, Canada.
Verma NK; Lymphocyte Signalling Research Laboratory, Lee Kong Chian School of Medicine, Nanyang Technological University, 636921, Singapore.; Singapore Eye Research Institute, The Academia, 20 College Road, 169856, Singapore.
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Źródło:
Scientific reports [Sci Rep] 2016 Nov 24; Vol. 6, pp. 37721. Date of Electronic Publication: 2016 Nov 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biological Transport/*physiology
Gene Silencing/*physiology
Oligonucleotides/*genetics
Oligonucleotides, Antisense/*genetics
Pinocytosis/*physiology
T-Lymphocytes/*physiology
Biological Transport/genetics ; Cells, Cultured ; Cytoskeletal Proteins/genetics ; Humans ; Pinocytosis/genetics ; Sorting Nexins/genetics ; Stathmin/genetics ; Transfection/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Experimental Design Approach for Methylene Blue Dye Removal in Aqueous Environment by Nitrilotriacetic Modified Banana Pith.
Autorzy:
Lee SL
Liew SW
Ong ST
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Źródło:
Acta chimica Slovenica [Acta Chim Slov] 2016; Vol. 63 (1), pp. 144-53.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Methylene Blue/*isolation & purification
Nitrilotriacetic Acid/*chemistry
Adsorption ; Hydrogen-Ion Concentration ; Methylene Blue/chemistry ; Research Design ; Spectroscopy, Fourier Transform Infrared
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 29

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