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Wyświetlanie 1-7 z 7
Tytuł :
Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney.
Autorzy :
Onozato ML; Division of Nephrology and Endocrinology, Department of Internal Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
Tojo A
Kobayashi N
Goto A
Matsuoka H
Fujita T
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Źródło :
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2007 May; Vol. 22 (5), pp. 1314-22. Date of Electronic Publication: 2007 Feb 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin-Converting Enzyme Inhibitors/*pharmacology
Hypertension/*metabolism
Kidney/*metabolism
Mineralocorticoid Receptor Antagonists/*pharmacology
NADPH Oxidases/*metabolism
Transforming Growth Factor beta/*metabolism
Aldosterone/physiology ; Angiotensin II/antagonists & inhibitors ; Angiotensin II/physiology ; Animals ; Cardiac Output, Low/metabolism ; Cardiac Output, Low/physiopathology ; Drug Synergism ; Eplerenone ; Hypertension/physiopathology ; Indoles/pharmacology ; Kidney/pathology ; Kidney/physiopathology ; Male ; Oxidative Stress/drug effects ; Rats ; Rats, Inbred Dahl ; Reactive Oxygen Species/metabolism ; Sodium-Potassium-Exchanging ATPase/metabolism ; Spironolactone/analogs & derivatives ; Spironolactone/pharmacology ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Eplerenone shows renoprotective effect by reducing LOX-1-mediated adhesion molecule, PKCepsilon-MAPK-p90RSK, and Rho-kinase pathway.
Autorzy :
Kobayashi N; Department of Hypertension and Cardiorenal Medicine, Dokkyo University School of Medicine, Mibu, Tochigi 321-0293, Japan. />Hara K
Tojo A
Onozato ML
Honda T
Yoshida K
Mita S
Nakano S
Tsubokou Y
Matsuoka H
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Źródło :
Hypertension (Dallas, Tex. : 1979) [Hypertension] 2005 Apr; Vol. 45 (4), pp. 538-44. Date of Electronic Publication: 2005 Feb 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Adhesion Molecules/*antagonists & inhibitors
Hypertension/*metabolism
Hypertension/*pathology
Protein Kinase Inhibitors/*pharmacology
Receptors, LDL/*antagonists & inhibitors
Spironolactone/*analogs & derivatives
Animals ; Cytoprotection ; Eplerenone ; Glomerulosclerosis, Focal Segmental/etiology ; Glomerulosclerosis, Focal Segmental/pathology ; Hypertension/complications ; Intracellular Signaling Peptides and Proteins ; Kidney/metabolism ; Kidney/pathology ; Male ; Mineralocorticoid Receptor Antagonists/pharmacology ; Mitogen-Activated Protein Kinases/antagonists & inhibitors ; Nitric Oxide Synthase/genetics ; Nitric Oxide Synthase Type III ; Protein Kinase C/antagonists & inhibitors ; Protein Kinase C-epsilon ; Protein-Serine-Threonine Kinases/antagonists & inhibitors ; Proteinuria/etiology ; Proteinuria/physiopathology ; RNA, Messenger/antagonists & inhibitors ; Rats ; Rats, Inbred Dahl ; Receptors, Oxidized LDL ; Ribosomal Protein S6 Kinases, 90-kDa/antagonists & inhibitors ; Scavenger Receptors, Class E ; Spironolactone/pharmacology ; rho-Associated Kinases
Czasopismo naukowe
Tytuł :
Expression and cellular localization of classic NADPH oxidase subunits in the spontaneously hypertensive rat kidney.
Autorzy :
Chabrashvili T; Division of Nephrology and Hypertension and Center for Hypertension and Renal Disease Research, Georgetown University Medical Center, Washington, DC 20007-2197, USA. />Tojo A
Onozato ML
Kitiyakara C
Quinn MT
Fujita T
Welch WJ
Wilcox CS
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Źródło :
Hypertension (Dallas, Tex. : 1979) [Hypertension] 2002 Feb; Vol. 39 (2), pp. 269-74.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Membrane Transport Proteins*
Hypertension/*enzymology
Kidney/*enzymology
NADPH Oxidases/*genetics
Animals ; Blotting, Western ; Gene Expression Regulation, Enzymologic ; Hypertension/genetics ; Immunohistochemistry ; Male ; NADPH Dehydrogenase/genetics ; NADPH Dehydrogenase/metabolism ; NADPH Oxidases/metabolism ; Phosphoproteins/genetics ; Phosphoproteins/metabolism ; Protein Subunits ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats ; Rats, Inbred SHR ; Rats, Inbred WKY ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Inhibitory Mechanisms of Dietary Calcium Intake Against Salt-Sensitive Hypertension.
Autorzy :
Kuwaki, Tomoyuki
Kobayashi, Mikako
Fujita, Megumi
Ono, Ayumu
Ling, Guang-Yi
Nagase, Miki
Onozato, Maristela Lika
Tojo, Akihiro
Ando, Katsuyuki
Kumada, Mamoru
Ichimaru, Yuhei
Fujita, Toshiro
Fukuda, Yasuichiro
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Temat :
CALCIUM
HYPERTENSION
BLOOD pressure
RATS
CALCIUM chloride
MEDICINE
Źródło :
Clinical & Experimental Hypertension; Jul2004, Vol. 26 Issue 5, p415-417, 2p
Czasopismo naukowe
    Wyświetlanie 1-7 z 7

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