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Tytuł:
Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain.
Autorzy:
Shao FB; Department of Neurobiology and Acupuncture Research, the Third School of Clinical Medicine, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou, 310053, China.
Fang JF; Department of Neurobiology and Acupuncture Research, the Third School of Clinical Medicine, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou, 310053, China.
Wang SS; Department of Neurobiology and Acupuncture Research, the Third School of Clinical Medicine, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou, 310053, China.
Qiu MT; Department of Neurobiology and Acupuncture Research, the Third School of Clinical Medicine, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou, 310053, China.
Xi DN; Department of Neurobiology and Acupuncture Research, the Third School of Clinical Medicine, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou, 310053, China.
Jin XM; Department of Anatomy and Cell Biology, Stark Neurosciences Research Institute, Indiana University School of Medicine, NB Building, 320w 15th Street #141, Indianapolis, IN, 46202, USA.
Liu JG; Department of Neurobiology and Acupuncture Research, the Third School of Clinical Medicine, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou, 310053, China.; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Shao XM; Department of Neurobiology and Acupuncture Research, the Third School of Clinical Medicine, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou, 310053, China.
Shen Z; Department of Neurobiology and Acupuncture Research, the Third School of Clinical Medicine, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou, 310053, China.
Liang Y; Department of Neurobiology and Acupuncture Research, the Third School of Clinical Medicine, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou, 310053, China.
Fang JQ; Department of Neurobiology and Acupuncture Research, the Third School of Clinical Medicine, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou, 310053, China. .
Du JY; Department of Neurobiology and Acupuncture Research, the Third School of Clinical Medicine, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou, 310053, China. .
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Źródło:
Molecular brain [Mol Brain] 2021 Sep 10; Vol. 14 (1), pp. 139. Date of Electronic Publication: 2021 Sep 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anxiety/*physiopathology
Chronic Pain/*physiopathology
GABAergic Neurons/*physiology
Gyrus Cinguli/*physiopathology
Inflammation/*psychology
Pyramidal Cells/*physiology
Animals ; Anti-Anxiety Agents/administration & dosage ; Anti-Anxiety Agents/pharmacology ; Anti-Anxiety Agents/therapeutic use ; Anxiety/drug therapy ; Anxiety/etiology ; Central Nervous System Sensitization/drug effects ; Chronic Pain/psychology ; Clozapine/therapeutic use ; Freund's Adjuvant/toxicity ; GABA-A Receptor Agonists/administration & dosage ; GABA-A Receptor Agonists/pharmacology ; GABA-A Receptor Agonists/therapeutic use ; GABA-A Receptor Antagonists/administration & dosage ; GABA-A Receptor Antagonists/pharmacology ; GABA-A Receptor Antagonists/toxicity ; GABAergic Neurons/enzymology ; Genetic Vectors/pharmacology ; Inflammation/chemically induced ; Inflammation/physiopathology ; Injections ; Interneurons/drug effects ; Male ; Muscimol/administration & dosage ; Muscimol/pharmacology ; Muscimol/therapeutic use ; Open Field Test ; Pain Threshold/drug effects ; Patch-Clamp Techniques ; Picrotoxin/toxicity ; Presynaptic Terminals/drug effects ; Presynaptic Terminals/physiology ; Pyramidal Cells/enzymology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The non-benzodiazepine anxiolytic etifoxine limits mechanical allodynia and anxiety-like symptoms in a mouse model of streptozotocin-induced diabetic neuropathy.
Autorzy:
Gazzo G; Centre National de la Recherche Scientifique, Institute for Cellular and Integrative Neuroscience (INCI), University of Strasbourg, Strasbourg, France.
Salgado Ferrer M; Centre National de la Recherche Scientifique, Institute for Cellular and Integrative Neuroscience (INCI), University of Strasbourg, Strasbourg, France.
Poisbeau P; Centre National de la Recherche Scientifique, Institute for Cellular and Integrative Neuroscience (INCI), University of Strasbourg, Strasbourg, France.
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Źródło:
PloS one [PLoS One] 2021 Aug 05; Vol. 16 (8), pp. e0248092. Date of Electronic Publication: 2021 Aug 05 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Analgesics/*therapeutic use
Anti-Anxiety Agents/*therapeutic use
Anxiety/*drug therapy
Diabetic Neuropathies/*drug therapy
Hyperalgesia/*drug therapy
Oxazines/*therapeutic use
Animals ; Anxiety/etiology ; Diabetes Mellitus, Experimental/complications ; Diabetic Neuropathies/complications ; GABA-A Receptor Agonists/therapeutic use ; Hyperalgesia/etiology ; Male ; Mice ; Mice, Inbred C57BL ; Open Field Test ; Pain Measurement
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mice with mutations in Trpm1, a gene in the locus of 15q13.3 microdeletion syndrome, display pronounced hyperactivity and decreased anxiety-like behavior.
Autorzy:
Hori T; Graduate School of Pharmacy, Ritsumeikan University, Kusatsu, Shiga, Japan.; Laboratory for Systems Neuroscience and Developmental Biology, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan.
Ikuta S; Laboratory for Systems Neuroscience and Developmental Biology, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan.; Graduate School of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan.
Hattori S; Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, Japan.
Takao K; Department of Behavioral Physiology, Faculty of Medicine, University of Toyama, Toyama, Toyama, Japan.; Research Center for Idling Brain Science, University of Toyama, Toyama, Toyama, Japan.; Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, Okazaki, Aichi, Japan.
Miyakawa T; Department of Behavioral Physiology, Faculty of Medicine, University of Toyama, Toyama, Toyama, Japan.
Koike C; Graduate School of Pharmacy, Ritsumeikan University, Kusatsu, Shiga, Japan. .; Laboratory for Systems Neuroscience and Developmental Biology, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan. .; Center for Systems Vision Science, Research Organization of Science and Technology, Ritsumeikan University, Kusatsu, Shiga, Japan. .; Ritsumeikan Global Innovation Research Organization (R-GIRO), Ritsumeikan University, Kusatsu, Shiga, Japan. .
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Źródło:
Molecular brain [Mol Brain] 2021 Mar 30; Vol. 14 (1), pp. 61. Date of Electronic Publication: 2021 Mar 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anxiety/*genetics
Chromosomes, Human, Pair 15/*genetics
Hyperkinesis/*genetics
TRPM Cation Channels/*genetics
Animals ; Biogenic Monoamines/analysis ; Brain Chemistry ; Exploratory Behavior ; Genetic Association Studies ; Humans ; Male ; Maze Learning/physiology ; Methylphenidate/pharmacology ; Mice ; Mice, Knockout ; Open Field Test ; Reflex, Startle ; Rotarod Performance Test ; Sequence Deletion ; Social Interaction ; Spatial Memory ; Swimming ; TRPM Cation Channels/deficiency ; Vision Disorders/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Whole-Genome Sequencing of Inbred Mouse Strains Selected for High and Low Open-Field Activity.
Autorzy:
Thomas AL; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, 447 UCB, Boulder, CO, USA.
Evans LM; Department of Ecology and Evolutionary Biology, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, 447 UCB, Boulder, CO, USA.
Nelsen MD; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.
Chesler EJ; Jackson Labs, Bar Harbor, ME, USA.
Powers MS; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, 447 UCB, Boulder, CO, USA.
Booher WC; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, 447 UCB, Boulder, CO, USA.
Lowry CA; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.; Center for Microbial Exploration, University of Colorado Boulder, Boulder, CO, USA.; Center for Neuroscience, University of Colorado Boulder, Boulder, CO, USA.; Department of Physical Medicine and Rehabilitation and Center for Neuroscience, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
DeFries JC; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.; Institute for Behavioral Genetics, University of Colorado Boulder, 447 UCB, Boulder, CO, USA.
Ehringer MA; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA. .; Center for Neuroscience, University of Colorado Boulder, Boulder, CO, USA. .; Institute for Behavioral Genetics, University of Colorado Boulder, 447 UCB, Boulder, CO, USA. .
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Źródło:
Behavior genetics [Behav Genet] 2021 Jan; Vol. 51 (1), pp. 68-81. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Anxiety/*genetics
Mice, Inbred Strains/*genetics
Open Field Test/*physiology
Animals ; Anxiety Disorders/genetics ; Chromosome Mapping/methods ; Computational Biology/methods ; Disease Models, Animal ; Genomics/methods ; Genotype ; Humans ; Mice ; Mice, Inbred BALB C/genetics ; Mice, Inbred C57BL/genetics ; Phenotype ; Polymorphism, Single Nucleotide/genetics ; Quantitative Trait Loci/genetics ; Rats ; Exome Sequencing/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tacr3 in the lateral habenula differentially regulates orofacial allodynia and anxiety-like behaviors in a mouse model of trigeminal neuralgia.
Autorzy:
Cui WQ; Department of Integrative Medicine and Neurobiology, Institutes of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, 130 Dong'an Road, Xuhui District, Shanghai, China.; Department of Pain Management, Shandong Provincial Qianfoshan Hospital, the First Hospital Affiliated with Shandong First Medical University, Jinan, Shandong, China.
Zhang WW; Department of Integrative Medicine and Neurobiology, Institutes of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, 130 Dong'an Road, Xuhui District, Shanghai, China.
Chen T; Department of Integrative Medicine and Neurobiology, Institutes of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, 130 Dong'an Road, Xuhui District, Shanghai, China.
Li Q; Department of Integrative Medicine and Neurobiology, Institutes of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, 130 Dong'an Road, Xuhui District, Shanghai, China.
Xu F; Department of Integrative Medicine and Neurobiology, Institutes of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, 130 Dong'an Road, Xuhui District, Shanghai, China.
Mao-Ying QL; Department of Integrative Medicine and Neurobiology, Institutes of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, 130 Dong'an Road, Xuhui District, Shanghai, China.
Mi WL; Department of Integrative Medicine and Neurobiology, Institutes of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, 130 Dong'an Road, Xuhui District, Shanghai, China.
Wang YQ; Department of Integrative Medicine and Neurobiology, Institutes of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, 130 Dong'an Road, Xuhui District, Shanghai, China.
Chu YX; Department of Integrative Medicine and Neurobiology, Institutes of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, 130 Dong'an Road, Xuhui District, Shanghai, China. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2020 Apr 07; Vol. 8 (1), pp. 44. Date of Electronic Publication: 2020 Apr 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anxiety/*genetics
Behavior, Animal/*physiology
Habenula/*metabolism
Hyperalgesia/*genetics
Neurons/*metabolism
Receptors, Neurokinin-3/*genetics
Trigeminal Neuralgia/*genetics
Animals ; Antipsychotic Agents/pharmacology ; Anxiety/physiopathology ; Anxiety/psychology ; Behavior, Animal/drug effects ; Clozapine/analogs & derivatives ; Clozapine/pharmacology ; Disease Models, Animal ; Elevated Plus Maze Test ; Glutamic Acid/metabolism ; Habenula/cytology ; Hyperalgesia/metabolism ; Hyperalgesia/physiopathology ; Hyperalgesia/psychology ; Maxillary Nerve/surgery ; Mice ; Neural Inhibition ; Open Field Test ; Transcriptome ; Trigeminal Neuralgia/metabolism ; Trigeminal Neuralgia/physiopathology ; Trigeminal Neuralgia/psychology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Scopoletin ameliorates anxiety-like behaviors in complete Freund's adjuvant-induced mouse model.
Autorzy:
Luo L; Precision Pharmacy & Drug Development Center, Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Sun T; Precision Pharmacy & Drug Development Center, Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Yang L; Precision Pharmacy & Drug Development Center, Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Liu A; Precision Pharmacy & Drug Development Center, Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Liu QQ; Precision Pharmacy & Drug Development Center, Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China.
Tian QQ; Department of Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an, 710032, China.
Wang Y; Department of Gastroenterology and Endoscopy Center, No. 986 Hospital, Fourth Military Medical University, Xi'an, 710054, China.
Zhao MG; Precision Pharmacy & Drug Development Center, Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China. .
Yang Q; Precision Pharmacy & Drug Development Center, Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, China. .
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Źródło:
Molecular brain [Mol Brain] 2020 Feb 04; Vol. 13 (1), pp. 15. Date of Electronic Publication: 2020 Feb 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Phytotherapy*
Angelica/*chemistry
Anti-Anxiety Agents/*therapeutic use
Anxiety/*drug therapy
Drugs, Chinese Herbal/*therapeutic use
GABA-A Receptor Agonists/*therapeutic use
Scopoletin/*therapeutic use
4-Aminobutyrate Transaminase/antagonists & inhibitors ; Amygdala/chemistry ; Amygdala/drug effects ; Animals ; Anti-Anxiety Agents/pharmacology ; Anxiety/etiology ; Cytokines/metabolism ; Disease Models, Animal ; Drugs, Chinese Herbal/pharmacology ; Elevated Plus Maze Test ; Freund's Adjuvant/toxicity ; GABA-A Receptor Agonists/pharmacology ; Inflammation/chemically induced ; Inflammation/psychology ; MAP Kinase Signaling System/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Microglia/drug effects ; Models, Molecular ; Molecular Docking Simulation ; NF-kappa B/metabolism ; Neurotransmitter Agents/metabolism ; Open Field Test ; Protein Conformation ; Receptors, Neurotransmitter/metabolism ; Scopoletin/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An Innovative Stress-Protective and Detoxification Substance for Reducing the Central Nervous System Effects of Alcohol Intoxication
Autorzy:
Shushpanova, T. V.Aff1, IDs11094023029813_cor1
Novozheeva, T. P.
Bokhan, N. A.Aff1, Aff2
Novitskaya, L. N.
Udut, V. V.
Smagina, M. I.
Matveenko, A. V.
Meleshko, M. V.
Kolomiets, N.É.
Garganeeva, N. P.Aff1, Aff2
Pod”yablonskii, A. S.
Safronov, S. M.
Boev, R. C.
Markova, E. V.
Knyazeva, E. M.
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Źródło:
Pharmaceutical Chemistry Journal. 57(7):1035-1042
Czasopismo naukowe
Szczegóły
Tytuł:
Evaluation of the anxiolytic activity of ethanolic extract of Ziziphus mauritiana Lam. in Swiss albino mice
Autorzy:
Priya Agrawal
Talever Singh
Devender Pathak
Himansu Chopra
Kuldeep Singh
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Temat:
Anxiety
Elevated plus maze
Ethanolic extract
Open field test
Ziziphus mauritiana
Other systems of medicine
RZ201-999
Therapeutics. Pharmacology
RM1-950
Źródło:
Pharmacological Research - Modern Chinese Medicine, Vol 10, Iss , Pp 100348- (2024)
Opis pliku:
electronic resource
Relacje:
http://www.sciencedirect.com/science/article/pii/S2667142523001343; https://doaj.org/toc/2667-1425
Dostęp URL:
https://doaj.org/article/acf9e417405943ce969846b820858cc6  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Cannabinoid type-2 receptors modulate terpene induced anxiety-reduction in zebrafish
Autorzy:
Andréa L. Johnson
Ryan Verbitsky
James Hudson
Rachel Dean
Trevor J. Hamilton
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Temat:
Endocannabinoid system
cannabis terpenes
zebrafish models
anxiety
CB2 receptors
open field test
Therapeutics. Pharmacology
RM1-950
Źródło:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115760- (2023)
Opis pliku:
electronic resource
Relacje:
http://www.sciencedirect.com/science/article/pii/S0753332223015585; https://doaj.org/toc/0753-3322
Dostęp URL:
https://doaj.org/article/b0f5717b9f604eaeb59e4214650f1208  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Acute neuroradiological, behavioral, and physiological effects of nose-only exposure to vaporized cannabis in C57BL/6 mice.
Autorzy:
Farra YM; Department of Bioengineering, Northeastern University, Boston, MA, USA.
Eden MJ; Department of Bioengineering, Northeastern University, Boston, MA, USA.
Coleman JR; Department of Psychology, Center for Translational NeuroImaging, Northeastern University, Boston, MA, USA.
Kulkarni P; Department of Psychology, Center for Translational NeuroImaging, Northeastern University, Boston, MA, USA.
Ferris CF; Department of Psychology, Center for Translational NeuroImaging, Northeastern University, Boston, MA, USA.
Oakes JM; Department of Bioengineering, Northeastern University, Boston, MA, USA.
Bellini C; Department of Bioengineering, Northeastern University, Boston, MA, USA.
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Źródło:
Inhalation toxicology [Inhal Toxicol] 2020 Apr; Vol. 32 (5), pp. 200-217. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Cannabis*
Marijuana Smoking*
Models, Animal*
Anxiety/*chemically induced
Behavior, Animal/*drug effects
Brain/*drug effects
Dronabinol/*blood
Administration, Inhalation ; Administration, Intranasal ; Aerosols ; Animals ; Brain/diagnostic imaging ; Humans ; Male ; Mice, Inbred C57BL ; Models, Biological ; Particle Size ; Respiratory System/metabolism ; Volatilization
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 240

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