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Tytuł :
Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2.
Autorzy :
Nomburg J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Program in Virology, Harvard University Graduate School of Arts and Sciences, Boston, MA, USA.
Meyerson M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. .; Broad Institute of MIT and Harvard, Cambridge, MA, USA. .; Department of Genetics, Harvard Medical School, Boston, MA, USA. .; Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA. .
DeCaprio JA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. .; Harvard Program in Virology, Harvard University Graduate School of Arts and Sciences, Boston, MA, USA. .; Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA. .
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Źródło :
Genome medicine [Genome Med] 2020 Dec 01; Vol. 12 (1), pp. 108. Date of Electronic Publication: 2020 Dec 01.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
5' Untranslated Regions*
Open Reading Frames*
Pandemics*
COVID-19/*epidemiology
COVID-19/*genetics
RNA, Viral/*genetics
SARS-CoV-2/*genetics
COVID-19/metabolism ; Humans ; RNA, Viral/metabolism ; SARS-CoV-2/metabolism
Czasopismo naukowe
Tytuł :
OASL Triggered by Novel Goose Astrovirus via ORF2 Restricts Its Replication.
Autorzy :
Ren D; Key Laboratory of Jiangsu Preventive Veterinary Medicine, Key Laboratory for Avian Preventive Medicine, Ministry of Education, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Centre for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China.
Li T; Key Laboratory of Jiangsu Preventive Veterinary Medicine, Key Laboratory for Avian Preventive Medicine, Ministry of Education, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Centre for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China.
Zhang X; Key Laboratory of Jiangsu Preventive Veterinary Medicine, Key Laboratory for Avian Preventive Medicine, Ministry of Education, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Centre for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China.
Yao X; Key Laboratory of Jiangsu Preventive Veterinary Medicine, Key Laboratory for Avian Preventive Medicine, Ministry of Education, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Centre for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China.
Gao W; Key Laboratory of Jiangsu Preventive Veterinary Medicine, Key Laboratory for Avian Preventive Medicine, Ministry of Education, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Centre for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China.
Xie Q; Key Laboratory of Jiangsu Preventive Veterinary Medicine, Key Laboratory for Avian Preventive Medicine, Ministry of Education, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Centre for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China.
Zhang J; Sinopharm Yangzhou VAC Biological Engineering Co. Ltd., Yangzhou, Jiangsu, China.
Shao H; Key Laboratory of Jiangsu Preventive Veterinary Medicine, Key Laboratory for Avian Preventive Medicine, Ministry of Education, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Centre for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China.
Wan Z; Key Laboratory of Jiangsu Preventive Veterinary Medicine, Key Laboratory for Avian Preventive Medicine, Ministry of Education, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Centre for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China.
Qin A; Key Laboratory of Jiangsu Preventive Veterinary Medicine, Key Laboratory for Avian Preventive Medicine, Ministry of Education, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Co-innovation Centre for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China.
Ye J; Key Laboratory of Jiangsu Preventive Veterinary Medicine, Key Laboratory for Avian Preventive Medicine, Ministry of Education, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China .; Jiangsu Co-innovation Centre for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety, the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, China.
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Źródło :
Journal of virology [J Virol] 2020 Nov 23; Vol. 94 (24). Date of Electronic Publication: 2020 Nov 23 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
2',5'-Oligoadenylate Synthetase/*metabolism
Astroviridae/*drug effects
Geese/*virology
Open Reading Frames/*drug effects
Virus Replication/*drug effects
2',5'-Oligoadenylate Synthetase/genetics ; 2',5'-Oligoadenylate Synthetase/pharmacology ; Animals ; Astroviridae/genetics ; Astroviridae Infections/immunology ; Astroviridae Infections/veterinary ; Astroviridae Infections/virology ; Cell Line ; Gene Knockdown Techniques ; Immunity, Innate ; Kinetics ; Open Reading Frames/physiology ; Poultry Diseases/immunology ; Poultry Diseases/virology ; Transcriptome ; Virus Replication/physiology
Czasopismo naukowe
Tytuł :
Sequence Analysis and Structure Prediction of SARS-CoV-2 Accessory Proteins 9b and ORF14: Evolutionary Analysis Indicates Close Relatedness to Bat Coronavirus.
Autorzy :
Baruah C; Bioinformatics Laboratory (DBT-Star College), P.G. Department of Zoology, Darrang College, Tezpur, 784 001 Assam, India.
Devi P; TCRP Foundation, 781006, Guwahati, India.
Sharma DK; School of Biological Sciences, University of Science and Technology, Meghalaya, Baridua-793101, India.
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Źródło :
BioMed research international [Biomed Res Int] 2020 Oct 20; Vol. 2020, pp. 7234961. Date of Electronic Publication: 2020 Oct 20 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Open Reading Frames*
COVID-19/*virology
Chiroptera/*virology
Coronavirus/*genetics
SARS-CoV-2/*genetics
Viral Proteins/*chemistry
Viral Proteins/*genetics
Amino Acid Sequence ; Animals ; Coronavirus/chemistry ; Coronavirus/metabolism ; Evolution, Molecular ; Genome, Viral ; Humans ; Models, Molecular ; Phylogeny ; Protein Conformation ; SARS-CoV-2/chemistry ; SARS-CoV-2/metabolism ; Sequence Analysis ; Virus Replication
Czasopismo naukowe
Tytuł :
Complete genome analysis of PaGz-1 and PaZq-1, two novel phages belonging to the genus Pakpunavirus.
Autorzy :
Wen L; CAS Key Laboratory of Quantitative Engineering Biology, Guangdong Provincial Key Laboratory of Synthetic Genomics, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Chen L; CAS Key Laboratory of Quantitative Engineering Biology, Guangdong Provincial Key Laboratory of Synthetic Genomics, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Yuan S; CAS Key Laboratory of Quantitative Engineering Biology, Guangdong Provincial Key Laboratory of Synthetic Genomics, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Tian L; College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Yan T; College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Zhang H; CAS Key Laboratory of Quantitative Engineering Biology, Guangdong Provincial Key Laboratory of Synthetic Genomics, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Tan Y; CAS Key Laboratory of Quantitative Engineering Biology, Guangdong Provincial Key Laboratory of Synthetic Genomics, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Yu Y; CAS Key Laboratory of Quantitative Engineering Biology, Guangdong Provincial Key Laboratory of Synthetic Genomics, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Wen H; CAS Key Laboratory of Quantitative Engineering Biology, Guangdong Provincial Key Laboratory of Synthetic Genomics, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Ma Y; CAS Key Laboratory of Quantitative Engineering Biology, Guangdong Provincial Key Laboratory of Synthetic Genomics, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Wei T; CAS Key Laboratory of Quantitative Engineering Biology, Guangdong Provincial Key Laboratory of Synthetic Genomics, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. .
Huang S; CAS Key Laboratory of Quantitative Engineering Biology, Guangdong Provincial Key Laboratory of Synthetic Genomics, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. .
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Źródło :
Archives of virology [Arch Virol] 2020 Oct; Vol. 165 (10), pp. 2393-2396. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji :
Journal Article
MeSH Terms :
Genome, Viral*
Open Reading Frames*
Phylogeny*
Myoviridae/*genetics
Pseudomonas Phages/*genetics
Pseudomonas aeruginosa/*virology
Base Sequence ; China ; Fresh Water/microbiology ; Gene Ontology ; Molecular Sequence Annotation ; Myoviridae/classification ; Myoviridae/isolation & purification ; Pseudomonas Phages/classification ; Pseudomonas Phages/isolation & purification ; Pseudomonas aeruginosa/isolation & purification ; Sequence Alignment ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Complete genome sequence of a novel bacteriophage, ATCEA85, infecting Enterobacter aerogenes.
Autorzy :
Oh HK; Department of Bioscience and Biotechnology, Hankuk University of Foreign Studies, Yong-In, 17035, Gyung-Gi Do, Republic of Korea.
Jo JH; Department of Bioscience and Biotechnology, Hankuk University of Foreign Studies, Yong-In, 17035, Gyung-Gi Do, Republic of Korea.
Hwang YJ; Department of Bioscience and Biotechnology, Hankuk University of Foreign Studies, Yong-In, 17035, Gyung-Gi Do, Republic of Korea.
Myung H; Department of Bioscience and Biotechnology, Hankuk University of Foreign Studies, Yong-In, 17035, Gyung-Gi Do, Republic of Korea. .; The Bacteriophage Bank of Korea, Yong-In, 17035, Gyung-Gi Do, Republic of Korea. .
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Źródło :
Archives of virology [Arch Virol] 2020 Oct; Vol. 165 (10), pp. 2397-2400. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article
MeSH Terms :
Genome, Viral*
Open Reading Frames*
Phylogeny*
DNA, Viral/*genetics
Enterobacter aerogenes/*virology
Siphoviridae/*genetics
Base Composition ; DNA/genetics ; Gene Ontology ; Molecular Sequence Annotation ; Siphoviridae/classification ; Siphoviridae/isolation & purification ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Revisiting the cysteine-rich proteins encoded in the 3'-proximal open reading frame of the positive-sense single-stranded RNA of some monopartite filamentous plant viruses: functional dissection of p15 from grapevine virus B.
Autorzy :
Davino S; Instituto de Biologia Molecular y Celular de Plantas (UPV-CSIC), Universidad Politécnica de Valencia, Avenida de los Naranjos, 46022, Valencia, Spain.; Department of Agricultural, Food and Forest Sciences, University of Palermo, Viale delle Scienze Building 5, 90128, Palermo, Italy.
Ruiz-Ruiz S; Instituto de Biologia Molecular y Celular de Plantas (UPV-CSIC), Universidad Politécnica de Valencia, Avenida de los Naranjos, 46022, Valencia, Spain.
Serra P; Instituto de Biologia Molecular y Celular de Plantas (UPV-CSIC), Universidad Politécnica de Valencia, Avenida de los Naranjos, 46022, Valencia, Spain.
Forment J; Instituto de Biologia Molecular y Celular de Plantas (UPV-CSIC), Universidad Politécnica de Valencia, Avenida de los Naranjos, 46022, Valencia, Spain.
Flores R; Instituto de Biologia Molecular y Celular de Plantas (UPV-CSIC), Universidad Politécnica de Valencia, Avenida de los Naranjos, 46022, Valencia, Spain. .
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Źródło :
Archives of virology [Arch Virol] 2020 Oct; Vol. 165 (10), pp. 2229-2239. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Open Reading Frames*
Flexiviridae/*genetics
RNA, Viral/*genetics
Viral Proteins/*genetics
Amino Acid Sequence ; Cloning, Molecular ; Evolution, Molecular ; Flexiviridae/metabolism ; Gene Expression ; Models, Molecular ; Phylogeny ; Plant Cells/virology ; Plant Leaves/virology ; Protein Conformation, alpha-Helical ; Protein Domains ; RNA, Viral/metabolism ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Sequence Alignment ; Sequence Homology, Amino Acid ; Tobacco/virology ; Viral Proteins/chemistry ; Viral Proteins/metabolism
SCR Organism :
Grapevine virus B
Czasopismo naukowe
Tytuł :
Characterization of accessory genes in coronavirus genomes.
Autorzy :
Michel CJ; Laboratoire ICube, Department of Computer Science, CNRS, University of Strasbourg, F-67412, Strasbourg, France.
Mayer C; Laboratoire ICube, Department of Computer Science, CNRS, University of Strasbourg, F-67412, Strasbourg, France.; Unité de Microbiologie Structurale, Institut Pasteur, CNRS UMR 3528, 75724, Paris Cedex 15, France.; Université Paris Diderot, Sorbonne Paris Cité, 75724, Paris Cedex 15, France.
Poch O; Laboratoire ICube, Department of Computer Science, CNRS, University of Strasbourg, F-67412, Strasbourg, France.
Thompson JD; Laboratoire ICube, Department of Computer Science, CNRS, University of Strasbourg, F-67412, Strasbourg, France. .
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Źródło :
Virology journal [Virol J] 2020 Aug 27; Vol. 17 (1), pp. 131. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genome, Viral*
Open Reading Frames*
Betacoronavirus/*genetics
SARS Virus/*genetics
Viral Regulatory and Accessory Proteins/*genetics
Animals ; Codon ; Computational Biology ; Evolution, Molecular ; Genes, Viral ; Humans ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Viral Matrix Proteins/genetics ; Viral Proteins/chemistry ; Viral Proteins/genetics ; Viral Regulatory and Accessory Proteins/chemistry
Czasopismo naukowe
Tytuł :
Porcine Epidemic Diarrhea Virus ORF3 Protein Is Transported through the Exocytic Pathway.
Autorzy :
Si F; Institute of Animal Science and Veterinary Medicine, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Shanghai Academy of Agricultural Sciences, Shanghai, People's Republic of China.; Shanghai Engineering Research Center of Breeding Pig, Shanghai, People's Republic of China.
Chen B; Institute of Animal Science and Veterinary Medicine, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Shanghai Academy of Agricultural Sciences, Shanghai, People's Republic of China.; Shanghai Engineering Research Center of Breeding Pig, Shanghai, People's Republic of China.
Hu X; Institute of Animal Science and Veterinary Medicine, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Shanghai Academy of Agricultural Sciences, Shanghai, People's Republic of China.
Yu R; Institute of Animal Science and Veterinary Medicine, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Shanghai Academy of Agricultural Sciences, Shanghai, People's Republic of China.; Shanghai Engineering Research Center of Breeding Pig, Shanghai, People's Republic of China.
Dong S; Institute of Animal Science and Veterinary Medicine, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Shanghai Academy of Agricultural Sciences, Shanghai, People's Republic of China.; Shanghai Engineering Research Center of Breeding Pig, Shanghai, People's Republic of China.
Wang R; Institute of Animal Science and Veterinary Medicine, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Shanghai Academy of Agricultural Sciences, Shanghai, People's Republic of China.
Li Z; Institute of Animal Science and Veterinary Medicine, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Shanghai Academy of Agricultural Sciences, Shanghai, People's Republic of China .; Shanghai Engineering Research Center of Breeding Pig, Shanghai, People's Republic of China.
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Źródło :
Journal of virology [J Virol] 2020 Aug 17; Vol. 94 (17). Date of Electronic Publication: 2020 Aug 17 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exocytosis*
Host-Pathogen Interactions*
Open Reading Frames*
Coronavirus Infections/*veterinary
Porcine epidemic diarrhea virus/*genetics
Swine Diseases/*metabolism
Swine Diseases/*virology
Viral Proteins/*metabolism
Amino Acid Sequence ; Animals ; Genetic Engineering ; Metabolic Networks and Pathways ; Plasmids/genetics ; Protein Transport ; Proteomics ; Swine ; Viral Proteins/chemistry ; Viral Proteins/genetics
Czasopismo naukowe
Tytuł :
Genomic variance of Open Reading Frames (ORFs) and Spike protein in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Autorzy :
Tsai PH; Cell Therapy Innovation Center, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Institute of Pharmacology, School of Pharmaceutical Science, National Yang-Ming University, Taipei, Taiwan, ROC.
Wang ML; Laboratory of Molecular Oncology, Basic Research Division, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Institute of Food Safety and Health Risk Assessment, National Yang-Ming University, Taipei, Taiwan, ROC.
Yang DM; Microscopy Service Laboratory, Basic Research Division, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Institute of Biophotonics, School of Medical Technology & Engineering, National Yang-Ming University, Taipei, Taiwan, ROC.; Biophotonics and Molecular Imaging Research Center (BMIRC), National Yang-Ming University, Taipei, Taiwan, ROC.
Liang KH; Institute of Food Safety and Health Risk Assessment, National Yang-Ming University, Taipei, Taiwan, ROC.; Laboratory of Systems Biomedical Science, Basic Research Division, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Chou SJ; Institute of Pharmacology, School of Pharmaceutical Science, National Yang-Ming University, Taipei, Taiwan, ROC.; Laboratory of Gene & Nanomedicine, Basic Research Division, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Chiou SH; Institute of Pharmacology, School of Pharmaceutical Science, National Yang-Ming University, Taipei, Taiwan, ROC.; Laboratory of Stem Cell II, Basic Research Division, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Lin TH; Laboratory of Nuclear Magnetic Resonance, Basic Research Division, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; Institute of BioMedical Informatics, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Wang CT; Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.; Laboratory of Molecular Virology, Basic Research Division, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Chang TJ; Laboratory of Genome Research, Basic Research Division, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.; School of Biomedical Science and Engineering, National Yang-Ming University, Taipei, Taiwan, ROC.
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Źródło :
Journal of the Chinese Medical Association : JCMA [J Chin Med Assoc] 2020 Aug; Vol. 83 (8), pp. 725-732.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genome, Viral*
Open Reading Frames*
Betacoronavirus/*genetics
Spike Glycoprotein, Coronavirus/*physiology
Humans ; Phylogeny ; Point Mutation ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/genetics
Czasopismo naukowe
Tytuł :
An efficient ORF selection system for DNA fragment libraries based on split beta-lactamase complementation.
Autorzy :
Verma V; Centre for Innovation in Infectious Disease Research, Education and Training (CIIDRET), University of Delhi South Campus, New Delhi, India.
Joshi G; Centre for Innovation in Infectious Disease Research, Education and Training (CIIDRET), University of Delhi South Campus, New Delhi, India.
Gupta A; Centre for Innovation in Infectious Disease Research, Education and Training (CIIDRET), University of Delhi South Campus, New Delhi, India.; Department of Biochemistry, University of Delhi South Campus, New Delhi, India.
Chaudhary VK; Centre for Innovation in Infectious Disease Research, Education and Training (CIIDRET), University of Delhi South Campus, New Delhi, India.; Department of Biochemistry, University of Delhi South Campus, New Delhi, India.
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Źródło :
PloS one [PLoS One] 2020 Jul 23; Vol. 15 (7), pp. e0235853. Date of Electronic Publication: 2020 Jul 23 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Open Reading Frames*
Bacterial Proteins/*genetics
Cloning, Molecular/*methods
Genetic Complementation Test/*methods
beta-Lactamases/*genetics
Bacterial Proteins/metabolism ; Escherichia coli ; Gene Library ; Mycobacterium tuberculosis ; beta-Lactamases/metabolism
Czasopismo naukowe
Tytuł :
Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2.
Autorzy :
Su YCF; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Anderson DE; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Young BE; National Centre for Infectious Diseases, Singapore.; Tan Tock Seng Hospital, Singapore.; Lee Kong Chian School of Medicine, Singapore.
Linster M; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Zhu F; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Jayakumar J; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Zhuang Y; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Kalimuddin S; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.; Singapore General Hospital, Singapore.
Low JGH; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.; Singapore General Hospital, Singapore.
Tan CW; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Chia WN; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Mak TM; National Centre for Infectious Diseases, Singapore.
Octavia S; National Centre for Infectious Diseases, Singapore.
Chavatte JM; National Centre for Infectious Diseases, Singapore.
Lee RTC; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore.
Pada S; Ng Teng Fong General Hospital, Singapore.
Tan SY; Changi General Hospital, Singapore.
Sun L; Alexandra Hospital, Singapore.
Yan GZ; National University Hospital, Singapore.
Maurer-Stroh S; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore.; Department of Biological Sciences, National University of Singapore, Singapore.
Mendenhall IH; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.; SingHealth Duke-NUS Global Health Institute, Singapore.
Leo YS; National Centre for Infectious Diseases, Singapore.; Tan Tock Seng Hospital, Singapore.; Lee Kong Chian School of Medicine, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Lye DC; National Centre for Infectious Diseases, Singapore.; Tan Tock Seng Hospital, Singapore.; Lee Kong Chian School of Medicine, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Wang LF; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore .; SingHealth Duke-NUS Global Health Institute, Singapore.; Duke Global Health Institute, Duke University, North Carolina, USA.
Smith GJD; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore .; SingHealth Duke-NUS Global Health Institute, Singapore.; Duke Global Health Institute, Duke University, North Carolina, USA.
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Źródło :
MBio [mBio] 2020 Jul 21; Vol. 11 (4). Date of Electronic Publication: 2020 Jul 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genome, Viral*
Open Reading Frames*
Betacoronavirus/*genetics
Base Sequence ; Betacoronavirus/immunology ; Betacoronavirus/physiology ; Humans ; SARS-CoV-2 ; Sequence Deletion ; Virus Replication
Czasopismo naukowe
Tytuł :
The Concerted Action of Two B3-Like Prophage Genes Excludes Superinfecting Bacteriophages by Blocking DNA Entry into Pseudomonas aeruginosa.
Autorzy :
Carballo-Ontiveros MA; Departamento de Genética y Biología Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Mexico.
Cazares A; EMBL's European Bioinformatics Institute and Wellcome Sanger Institute, Hinxton, Cambridgeshire, United Kingdom.
Vinuesa P; Programa de Ingeniería Genómica, Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico.
Kameyama L; Departamento de Genética y Biología Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Mexico.
Guarneros G; Departamento de Genética y Biología Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Mexico .
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Źródło :
Journal of virology [J Virol] 2020 Jul 16; Vol. 94 (15). Date of Electronic Publication: 2020 Jul 16 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA, Viral*/genetics
DNA, Viral*/metabolism
Genes, Viral*
Open Reading Frames*
Prophages*/genetics
Prophages*/metabolism
Pseudomonas Phages*/genetics
Pseudomonas Phages*/metabolism
Pseudomonas aeruginosa*/genetics
Pseudomonas aeruginosa*/metabolism
Pseudomonas aeruginosa*/virology
Czasopismo naukowe
Tytuł :
5'-UTR and ORF elements, as well as the 3'-UTR regulate the translation of Cyclin.
Autorzy :
Kim B; Department of Biological Science, Inje University, 197 Inje-ro, Gimhae, Gyeongnam, 50834, Republic of Korea.
Kim HM; Department of Biological Science, Inje University, 197 Inje-ro, Gimhae, Gyeongnam, 50834, Republic of Korea; Institute of Digital Anti-Aging Healthcare, Inje University, 197 Inje-ro, Gimhae, Gyeongnam, 50834, Republic of Korea.
Kang MK; Department of Biological Science, Inje University, 197 Inje-ro, Gimhae, Gyeongnam, 50834, Republic of Korea; Department of Research Center, Dong Nam Institute of Radiological and Medical Sciences, 40 Jwadong-gil, Gijang-gun, Busan, 46033, Republic of Korea.
Sohn DH; Department of Microbiology and Immunology, Pusan National University School of Medicine, Yangsan, Gyeongnam, 50612, Republic of Korea.
Han SJ; Department of Biological Science, Inje University, 197 Inje-ro, Gimhae, Gyeongnam, 50834, Republic of Korea; Institute of Digital Anti-Aging Healthcare, Inje University, 197 Inje-ro, Gimhae, Gyeongnam, 50834, Republic of Korea; Department of Biotechnology, Inje University, 197 Inje-ro, Gimhae, Gyeongnam, 50834, Republic of Korea; Institute of Basic Science, Inje University, 197 Inje-ro, Gimhae, Gyeongnam, 50834, Republic of Korea. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Jul 05; Vol. 527 (4), pp. 968-973. Date of Electronic Publication: 2020 May 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Open Reading Frames*
Protein Biosynthesis*
Cyclin B1/*genetics
Cyclin B2/*genetics
3' Untranslated Regions ; 5' Untranslated Regions ; Animals ; Female ; HEK293 Cells ; Humans ; Mice, Inbred C57BL ; Oocytes/metabolism
Czasopismo naukowe
Tytuł :
The open reading frame 02797 from Candida tropicalis encodes a novel NADH-dependent aldehyde reductase.
Autorzy :
Hu X; Institute of Resources and Geographic Information Technology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China.
Han X; Institute of Resources and Geographic Information Technology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China.
Wu L; Institute of Resources and Geographic Information Technology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China.
Wang H; Institute of Resources and Geographic Information Technology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China.
Ouyang Y; Institute of Resources and Geographic Information Technology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China.
Li Q; Institute of Resources and Geographic Information Technology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China.
Kuang X; Institute of Resources and Geographic Information Technology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China.
Xiang Q; Department of Applied Microbiology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China.
Yu X; Department of Applied Microbiology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China.
Li X; College of Landscape Architecture, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China.
Gu Y; Department of Applied Microbiology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China.
Zhao K; Department of Applied Microbiology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China.
Chen Q; Department of Applied Microbiology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China.
Ma M; Institute of Resources and Geographic Information Technology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China; Department of Applied Microbiology, College of Resources, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, Sichuan, PR China. Electronic address: .
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Źródło :
Protein expression and purification [Protein Expr Purif] 2020 Jul; Vol. 171, pp. 105625. Date of Electronic Publication: 2020 Mar 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Open Reading Frames*
Aldehyde Reductase/*metabolism
Candida tropicalis/*enzymology
Cytoplasm/*enzymology
Fungal Proteins/*metabolism
NADP/*metabolism
Aldehyde Reductase/genetics ; Candida tropicalis/genetics ; Cytoplasm/genetics ; Fungal Proteins/genetics ; NADP/genetics
Czasopismo naukowe
Tytuł :
Evolution of new proteins from translated sORFs in long non-coding RNAs.
Autorzy :
Ruiz-Orera J; Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.
Villanueva-Cañas JL; Molecular Biology CORE, Hospital Clínic, Universitat de Barcelona, Spain.
Albà MM; Evolutionary Genomics Group, Research Programme in Biomedical Informatics, Hospital Del Mar Research Institute (IMIM), Universitat Pompeu Fabra (UPF), Barcelona, Spain; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, 08010, Spain. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2020 Jun 01; Vol. 391 (1), pp. 111940. Date of Electronic Publication: 2020 Mar 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Evolution, Molecular*
Genome*
Open Reading Frames*
Protein Biosynthesis*
RNA, Long Noncoding/*genetics
Ribosomes/*genetics
Animals ; Brain/metabolism ; Humans ; Liver/metabolism ; Male ; Molecular Sequence Annotation ; Myocardium/metabolism ; Organ Specificity ; RNA, Long Noncoding/classification ; RNA, Long Noncoding/metabolism ; Ribosomes/classification ; Ribosomes/metabolism ; Testis/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Non-AUG start codons: Expanding and regulating the small and alternative ORFeome.
Autorzy :
Cao X; Department of Chemistry, Yale University, New Haven, CT, 06520, United States; Chemical Biology Institute, Yale University, West Haven, CT, 06516, United States.
Slavoff SA; Department of Chemistry, Yale University, New Haven, CT, 06520, United States; Chemical Biology Institute, Yale University, West Haven, CT, 06516, United States; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06529, United States. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2020 Jun 01; Vol. 391 (1), pp. 111973. Date of Electronic Publication: 2020 Mar 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Genome*
Open Reading Frames*
Peptide Chain Initiation, Translational*
Codon, Initiator/*chemistry
Proteome/*genetics
Ribosomes/*genetics
Codon, Initiator/metabolism ; Computational Biology/methods ; Eukaryota/genetics ; Eukaryota/metabolism ; High-Throughput Nucleotide Sequencing ; Molecular Sequence Annotation/methods ; Prokaryotic Cells/metabolism ; Protein Sorting Signals/genetics ; Proteome/classification ; Proteome/metabolism ; Ribosomes/classification ; Ribosomes/metabolism
Czasopismo naukowe
Tytuł :
The hunt for sORFs: A multidisciplinary strategy.
Autorzy :
Peeters MKR; BioBix, Department of Data Analysis and Mathematical Modelling, Ghent University, Coupure Links 653, 900, Gent, Belgium.
Menschaert G; BioBix, Department of Data Analysis and Mathematical Modelling, Ghent University, Coupure Links 653, 900, Gent, Belgium. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2020 Jun 01; Vol. 391 (1), pp. 111923. Date of Electronic Publication: 2020 Mar 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Neural Networks, Computer*
Open Reading Frames*
Protein Biosynthesis*
Computational Biology/*statistics & numerical data
Proteome/*genetics
Ribosomes/*genetics
Animals ; Computational Biology/methods ; High-Throughput Nucleotide Sequencing ; Humans ; Plants/genetics ; Protein Sorting Signals/genetics ; Proteome/classification ; Proteome/metabolism ; Ribosomes/classification ; Ribosomes/metabolism ; Software
Czasopismo naukowe
Tytuł :
Coding and noncoding somatic mutations in candidate genes in basal cell carcinoma.
Autorzy :
Maturo MG; Department of Dermatology, Department of Biotechnology and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Rachakonda S; Division of Functional Genome Analysis, German Cancer Research Center, Heidelberg, Germany.; Division of Molecular Genetic epidemiology, German Cancer Research Center, Heidelberg, Germany.
Heidenreich B; Division of Molecular Genetic epidemiology, German Cancer Research Center, Heidelberg, Germany.
Pellegrini C; Department of Dermatology, Department of Biotechnology and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Srinivas N; Division of Functional Genome Analysis, German Cancer Research Center, Heidelberg, Germany.
Requena C; Department of Dermatology, Instituto Valenciano de Oncología, València, Spain.
Serra-Guillen C; Department of Dermatology, Instituto Valenciano de Oncología, València, Spain.
Llombart B; Department of Dermatology, Instituto Valenciano de Oncología, València, Spain.
Sanmartin O; Department of Dermatology, Instituto Valenciano de Oncología, València, Spain.
Guillen C; Department of Dermatology, Instituto Valenciano de Oncología, València, Spain.
Di Nardo L; Institute of Dermatology, Catholic University of Sacred Heart, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Peris K; Institute of Dermatology, Catholic University of Sacred Heart, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Fargnoli MC; Department of Dermatology, Department of Biotechnology and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Nagore E; Department of Dermatology, Instituto Valenciano de Oncología, València, Spain.
Kumar R; Division of Functional Genome Analysis, German Cancer Research Center, Heidelberg, Germany. .; Division of Molecular Genetic epidemiology, German Cancer Research Center, Heidelberg, Germany. .
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Źródło :
Scientific reports [Sci Rep] 2020 May 14; Vol. 10 (1), pp. 8005. Date of Electronic Publication: 2020 May 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor*
Mutation*
Open Reading Frames*
Untranslated Regions*
Carcinoma, Basal Cell/*genetics
DNA Methylation ; Epigenesis, Genetic ; Gene Expression Regulation, Neoplastic ; Humans ; Promoter Regions, Genetic ; Skin Neoplasms/genetics
Czasopismo naukowe
Tytuł :
Comprehensive analysis of the expression profile of circRNAs and their predicted protein-coding ability in the muscle of mdx mice.
Autorzy :
Song Z; Department of Neurology, the First Affiliated Hospital, Sun Yat-sen University, No 58, Zhongshan 2 Road, Guangzhou, 510080, Guangdong Province, People's Republic of China.
Liu Y; Department of Neurology, the First Affiliated Hospital, Sun Yat-sen University, No 58, Zhongshan 2 Road, Guangzhou, 510080, Guangdong Province, People's Republic of China.
Fang X; Department of Neurology, the First Affiliated Hospital, Sun Yat-sen University, No 58, Zhongshan 2 Road, Guangzhou, 510080, Guangdong Province, People's Republic of China.
Xie M; Department of Rehabilitation, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong Province, People's Republic of China.
Ma Z; Department of Neurology, the Second Affiliated Hospital, Guangzhou Medicine University, Guangzhou, Guangdong Province, People's Republic of China.
Zhong Z; Department of Neurology, Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, People's Republic of China.
Feng X; Department of Neurology, the First Affiliated Hospital, Sun Yat-sen University, No 58, Zhongshan 2 Road, Guangzhou, 510080, Guangdong Province, People's Republic of China.
Zhang W; Department of Neurology, the First Affiliated Hospital, Sun Yat-sen University, No 58, Zhongshan 2 Road, Guangzhou, 510080, Guangdong Province, People's Republic of China. .
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Źródło :
Functional & integrative genomics [Funct Integr Genomics] 2020 May; Vol. 20 (3), pp. 397-407. Date of Electronic Publication: 2019 Nov 18.
Typ publikacji :
Journal Article
MeSH Terms :
Open Reading Frames*
Muscle, Skeletal/*metabolism
Muscular Dystrophy, Duchenne/*genetics
RNA, Circular/*genetics
Animals ; Gene Regulatory Networks ; Mice ; Mice, Inbred C57BL ; Mice, Inbred mdx ; MicroRNAs/genetics ; MicroRNAs/metabolism ; RNA, Circular/chemistry ; RNA, Circular/metabolism ; Transcriptome
Czasopismo naukowe

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