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Wyszukujesz frazę ""Opioid Peptides"" wg kryterium: Temat


Tytuł :
[The role of nociceptin in opioid regulation of brain functions].
Autorzy :
Shamakina IY; V.P. Serbsky National Medical Research Center on Psychiatry and Addiction, Moscow, Russia.
Shagiakhmetov FS; The Institute of General Pathology and Pathophysiology, Moscow, Russia.
Anokhin PK; V.P. Serbsky National Medical Research Center on Psychiatry and Addiction, Moscow, Russia.
Kohan VS; V.P. Serbsky National Medical Research Center on Psychiatry and Addiction, Moscow, Russia.
Davidova TV; The Institute of General Pathology and Pathophysiology, Moscow, Russia.
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Transliterated Title :
Rol' notsitseptina v mekhanizmakh opioidnoĭ reguliatsii funktsiĭ mozga.
Źródło :
Biomeditsinskaia khimiia [Biomed Khim] 2021 Jan; Vol. 67 (1), pp. 5-16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Analgesics, Opioid*
Opioid Peptides*/metabolism
Anxiety ; Brain/metabolism
Czasopismo naukowe
Tytuł :
Fear expression is reduced after acute and repeated nociceptin/orphanin FQ (NOP) receptor antagonism in rats: therapeutic implications for traumatic stress exposure.
Autorzy :
Taylor RM; Behavioral Biology Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD, 20910, USA. .
Jeong IH; Behavioral Biology Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD, 20910, USA.
May MD; Behavioral Biology Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD, 20910, USA.
Bergman EM; Behavioral Biology Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD, 20910, USA.
Capaldi VF; Behavioral Biology Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD, 20910, USA.
Moore NLT; Behavioral Biology Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD, 20910, USA.
Matson LM; Behavioral Biology Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD, 20910, USA.
Lowery-Gionta EG; Behavioral Biology Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD, 20910, USA. .
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2020 Oct; Vol. 237 (10), pp. 2943-2958. Date of Electronic Publication: 2020 Jun 25.
Typ publikacji :
Journal Article
MeSH Terms :
Receptors, Opioid*/metabolism
Benzimidazoles/*administration & dosage
Cycloheptanes/*administration & dosage
Fear/*psychology
Opioid Peptides/*antagonists & inhibitors
Piperidines/*administration & dosage
Stress Disorders, Post-Traumatic/*drug therapy
Animals ; Dose-Response Relationship, Drug ; Exploratory Behavior/drug effects ; Exploratory Behavior/physiology ; Fear/drug effects ; Fear/physiology ; Male ; Memory/drug effects ; Memory/physiology ; Opioid Peptides/metabolism ; Rats ; Rats, Sprague-Dawley ; Stress Disorders, Post-Traumatic/metabolism ; Stress Disorders, Post-Traumatic/psychology
Czasopismo naukowe
Tytuł :
Biased signaling by endogenous opioid peptides.
Autorzy :
Gomes I; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
Sierra S; Department of Physiology & Biophysics, Virginia Commonwealth University, Richmond, VA 23298.
Lueptow L; Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90095.
Gupta A; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
Gouty S; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University, Bethesda MD 20814.
Margolis EB; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, CA 94143.
Cox BM; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University, Bethesda MD 20814.
Devi LA; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 May 26; Vol. 117 (21), pp. 11820-11828. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Opioid Peptides*/agonists
Opioid Peptides*/metabolism
Receptors, Opioid/*metabolism
Signal Transduction/*physiology
Animals ; Cell Line, Tumor ; Humans ; Male ; Pro-Opiomelanocortin/metabolism ; Protein Binding ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Potent, Efficacious, and Stable Cyclic Opioid Peptides with Long Lasting Antinociceptive Effect after Peripheral Administration.
Autorzy :
Stefanucci A; Dipartimento di Farmacia, Università di Chieti-Pescara 'G. d'Annunzio', Via dei Vestini 31, 66100 Chieti, Italy.
Dimmito MP; Dipartimento di Farmacia, Università di Chieti-Pescara 'G. d'Annunzio', Via dei Vestini 31, 66100 Chieti, Italy.
Macedonio G; Dipartimento di Farmacia, Università di Chieti-Pescara 'G. d'Annunzio', Via dei Vestini 31, 66100 Chieti, Italy.
Ciarlo L; Istituto Superiore di Sanità, Centro Nazionale Ricerca e Valutazione Preclinica e Clinica dei Farmaci, Viale Regina Elena 299, 00161 Rome, Italy.
Pieretti S; Istituto Superiore di Sanità, Centro Nazionale Ricerca e Valutazione Preclinica e Clinica dei Farmaci, Viale Regina Elena 299, 00161 Rome, Italy.
Novellino E; Dipartimento di Farmacia, Università di Napoli 'Federico II', Via D. Montesano, 49, 80131 Naples, Italy.
Lei W; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona 85724, United States.
Barlow D; Department of Biomedical Sciences, College of Osteopathic Medicine, University of New England, Biddeford, Maine 04005, United States.
Houseknecht KL; Department of Biomedical Sciences, College of Osteopathic Medicine, University of New England, Biddeford, Maine 04005, United States.
Streicher JM; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona 85724, United States.
Mollica A; Dipartimento di Farmacia, Università di Chieti-Pescara 'G. d'Annunzio', Via dei Vestini 31, 66100 Chieti, Italy.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Mar 12; Vol. 63 (5), pp. 2673-2687. Date of Electronic Publication: 2019 Dec 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Analgesics, Opioid/*therapeutic use
Opioid Peptides/*therapeutic use
Pain/*drug therapy
Peptides, Cyclic/*therapeutic use
Administration, Intravenous ; Analgesics, Opioid/administration & dosage ; Analgesics, Opioid/pharmacokinetics ; Analgesics, Opioid/pharmacology ; Animals ; CHO Cells ; Cricetulus ; Female ; Humans ; Infusions, Subcutaneous ; Male ; Mice ; Models, Molecular ; Opioid Peptides/administration & dosage ; Opioid Peptides/pharmacokinetics ; Opioid Peptides/pharmacology ; Pain/metabolism ; Peptides, Cyclic/administration & dosage ; Peptides, Cyclic/pharmacokinetics ; Peptides, Cyclic/pharmacology ; Receptors, Opioid/metabolism
Czasopismo naukowe
Tytuł :
The influence of the stereochemistry and C-end chemical modification of dermorphin derivatives on the peptide-phospholipid interactions.
Autorzy :
Trzeciak K; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, 90-363 Łódź, Sienkiewicza 112, Poland.
Paluch P; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, 90-363 Łódź, Sienkiewicza 112, Poland.
Pawlak T; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, 90-363 Łódź, Sienkiewicza 112, Poland.
Różański A; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, 90-363 Łódź, Sienkiewicza 112, Poland.
Dudek MK; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, 90-363 Łódź, Sienkiewicza 112, Poland. Electronic address: .
Potrzebowski MJ; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, 90-363 Łódź, Sienkiewicza 112, Poland. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2020 Feb 01; Vol. 1862 (2), pp. 183066. Date of Electronic Publication: 2019 Oct 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lipid Bilayers/*chemistry
Opioid Peptides/*chemistry
Phospholipids/*metabolism
Amino Acids, Aromatic ; Dimyristoylphosphatidylcholine/metabolism ; Hydrophobic and Hydrophilic Interactions ; Molecular Conformation ; Opioid Peptides/metabolism ; Stereoisomerism
Czasopismo naukowe
Tytuł :
D-Amino Acids in Peptides from Animals, Including Human: Occurrence, Structure, Bioactivity and Pharmacology.
Autorzy :
Jimenez EC; Department of Physical Sciences, College of Science, University of the Philippines Baguio, Baguio City 2600, Philippines.
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Źródło :
Current protein & peptide science [Curr Protein Pept Sci] 2020; Vol. 21 (6), pp. 622-637.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Amino Acids/*chemistry
Conotoxins/*chemistry
Invertebrate Hormones/*chemical synthesis
Nerve Tissue Proteins/*chemistry
Opioid Peptides/*chemistry
Pore Forming Cytotoxic Proteins/*chemistry
Amino Acid Sequence ; Amino Acids/metabolism ; Animals ; Cardiovascular Agents/chemistry ; Cardiovascular Agents/metabolism ; Cardiovascular Agents/pharmacology ; Conotoxins/biosynthesis ; Conotoxins/pharmacology ; Crustacea/chemistry ; Crustacea/metabolism ; Fibrinopeptide A/biosynthesis ; Fibrinopeptide A/chemistry ; Fibrinopeptide A/pharmacology ; Humans ; Invertebrate Hormones/biosynthesis ; Invertebrate Hormones/chemistry ; Invertebrate Hormones/pharmacology ; Mollusca/chemistry ; Mollusca/metabolism ; Natriuretic Peptides/biosynthesis ; Natriuretic Peptides/chemistry ; Natriuretic Peptides/pharmacology ; Nerve Tissue Proteins/biosynthesis ; Nerve Tissue Proteins/pharmacology ; Opioid Peptides/biosynthesis ; Opioid Peptides/pharmacology ; Pore Forming Cytotoxic Proteins/biosynthesis ; Pore Forming Cytotoxic Proteins/pharmacology ; Species Specificity ; Spiders/chemistry ; Spiders/metabolism ; Stereoisomerism
Czasopismo naukowe
Tytuł :
The Complex Role of Nociceptin Signaling in Stress: Clarity Through Neuroimaging?
Autorzy :
Piantadosi SC; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, Washington; Department of Anesthesiology, University of Washington, Seattle, Washington.
Pizzagalli DA; Center for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, Massachusetts; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts.
Bruchas MR; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, Washington; Department of Anesthesiology, University of Washington, Seattle, Washington. Electronic address: .
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Źródło :
Biological psychiatry [Biol Psychiatry] 2020 Mar 15; Vol. 87 (6), pp. 489-491.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Opioid Peptides*
Receptors, Opioid*
Neuroimaging ; Signal Transduction
Czasopismo naukowe
Tytuł :
Dermorphin [D-Arg2, Lys4] (1-4) amide inhibits below-level heat hypersensitivity in mice after contusive thoracic spinal cord injury.
Autorzy :
Liu S; Department of Orthopedics, Honghui Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China.; Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.
Huang Q; Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.
He S; Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.
Chen Z; Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.
Gao X; Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.; Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, China.
Ma D; Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.; Department of Anesthesiology, Chaoyang Hospital, Capital Medical University, Beijing, China.
Duan W; Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.; Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Ford N; Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.
Yang F; Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.; Department of Neurobiology, School of Basic Medical Sciences, Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
Chen X; Department of Orthopedics, Luhe Hospital, Capital Medical University, Beijing, China.
Raja SN; Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.
Hao D; Department of Orthopedics, Honghui Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China.
Guan Y; Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.; Department of Neurological Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD, United States.
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Źródło :
Pain [Pain] 2019 Dec; Vol. 160 (12), pp. 2710-2723.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Analgesics, Opioid/*therapeutic use
Hyperalgesia/*drug therapy
Opioid Peptides/*therapeutic use
Receptors, Opioid, mu/*agonists
Spinal Cord Injuries/*complications
Analgesics, Opioid/pharmacology ; Animals ; Conditioning, Operant/drug effects ; Hot Temperature ; Hyperalgesia/etiology ; Hyperalgesia/physiopathology ; Male ; Mice ; Motor Activity/drug effects ; Opioid Peptides/pharmacology ; Pain Threshold/drug effects ; Spinal Cord Injuries/physiopathology ; Thoracic Vertebrae
Czasopismo naukowe
Tytuł :
Abnormal behavior, striatal dopamine turnover and opioid peptide gene expression in histamine-deficient mice.
Autorzy :
Abdurakhmanova S; Department of Anatomy, University of Helsinki, Helsinki, Finland.
Semenova S; Department of Anatomy, University of Helsinki, Helsinki, Finland.
Piepponen TP; Division of Pharmacology and Pharmacotherapy, University of Helsinki, Helsinki, Finland.
Panula P; Department of Anatomy, University of Helsinki, Helsinki, Finland.
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Źródło :
Genes, brain, and behavior [Genes Brain Behav] 2019 Nov; Vol. 18 (8), pp. e12595. Date of Electronic Publication: 2019 Jul 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Movement*
Corpus Striatum/*metabolism
Dopamine/*metabolism
Histamine/*metabolism
Histidine Decarboxylase/*genetics
Opioid Peptides/*genetics
3,4-Dihydroxyphenylacetic Acid/metabolism ; Animals ; Corpus Striatum/physiopathology ; Histamine/deficiency ; Histidine Decarboxylase/deficiency ; Male ; Mice ; Mice, Inbred C57BL ; Opioid Peptides/metabolism ; Serotonin/metabolism
Czasopismo naukowe
Tytuł :
Dermorphin: A Missed Palliative Care Opportunity for Intrathecal Therapy in Oncological Patients?
Autorzy :
Liebregts R; Department of Anaesthesiology and Pain Medicine - Location VUmc, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Keppel Hesselink JM; Faculty of Health, University of Witten/Herdecke, Witten, Germany.; Institute for Neuropathic Pain, Amsterdam, The Netherlands.
Kopsky DJ; Institute for Neuropathic Pain, Amsterdam, The Netherlands.
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Źródło :
Pain medicine (Malden, Mass.) [Pain Med] 2019 Oct 01; Vol. 20 (10), pp. 2077-2079.
Typ publikacji :
Journal Article
MeSH Terms :
Palliative Care*
Analgesics, Opioid/*therapeutic use
Cancer Pain/*drug therapy
Neoplasms/*complications
Opioid Peptides/*therapeutic use
Analgesics, Opioid/administration & dosage ; Humans ; Injections, Spinal ; Opioid Peptides/administration & dosage ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł :
Non-addictive orally-active kappa opioid agonists for the treatment of peripheral pain in rats.
Autorzy :
Beck TC; Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina Campus, 280 Calhoun Street, P.O. Box 250140, Charleston, SC, 29424-2303, USA.
Reichel CM; Department of Neurosciences, Medical University of South Carolina, 173 Ashley Ave., Room 416A BSB, Charleston, SC, 29424-2303, USA.
Helke KL; Department of Comparative Medicine, Medical University of South Carolina, 11 Doughty St., Room 640, Charleston, SC, 29424-2303, USA.
Bhadsavle SS; Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina Campus, 280 Calhoun Street, P.O. Box 250140, Charleston, SC, 29424-2303, USA.
Dix TA; Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina Campus, 280 Calhoun Street, P.O. Box 250140, Charleston, SC, 29424-2303, USA. Electronic address: http://academicdepartments.musc.edu/facultydirectory/FacultyDetails.aspx?facultyId=1662.
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2019 Aug 05; Vol. 856, pp. 172396. Date of Electronic Publication: 2019 May 16.
Typ publikacji :
Journal Article
MeSH Terms :
Analgesics/*pharmacology
Opioid Peptides/*pharmacology
Pain/*drug therapy
Receptors, Opioid, kappa/*agonists
Administration, Oral ; Analgesics/administration & dosage ; Analgesics/therapeutic use ; Analgesics/toxicity ; Animals ; Conditioning, Psychological/drug effects ; Locomotion/drug effects ; Male ; Opioid Peptides/administration & dosage ; Opioid Peptides/therapeutic use ; Opioid Peptides/toxicity ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Endogenous opioid and cannabinoid systems contribute to antinociception produced by administration of NSAIDs into the insular cortex of rats.
Autorzy :
Tsagareli N; Department of Pain and Analgesia, Beritashvili Center for Experimental Biomedicine, Tbilisi, Georgia; Department of Physiology, Tbilisi State Medial University, Tbilisi, Georgia.
Tsiklauri N; Department of Pain and Analgesia, Beritashvili Center for Experimental Biomedicine, Tbilisi, Georgia.
Kvachadze I; Department of Physiology, Tbilisi State Medial University, Tbilisi, Georgia.
Tsagareli MG; Department of Pain and Analgesia, Beritashvili Center for Experimental Biomedicine, Tbilisi, Georgia; Department of Physiology, Tbilisi State Medial University, Tbilisi, Georgia. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Nov; Vol. 131, pp. 110722. Date of Electronic Publication: 2020 Sep 08.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Cerebral Cortex/*drug effects
Endocannabinoids/*physiology
Nociception/*drug effects
Opioid Peptides/*physiology
Analgesia ; Animals ; Cerebral Cortex/physiology ; Male ; Naloxone/pharmacology ; Nociception/physiology ; Piperidines/pharmacology ; Pyrazoles/pharmacology ; Rats ; Rats, Wistar ; Somatostatin/analogs & derivatives ; Somatostatin/pharmacology
Czasopismo naukowe
Tytuł :
Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH 2 .
Autorzy :
Pacifico S; Department of Chemical and Pharmaceutical Sciences, University of Ferrara, Via Luigi Borsari 46, 44121 Ferrara, Italy.
Ferrari F; Department of Medical Sciences, Section of Pharmacology, University of Ferrara, Via Fossato di Mortara 17/19, 44121 Ferrara, Italy.
Albanese V; Department of Chemical and Pharmaceutical Sciences, University of Ferrara, Via Luigi Borsari 46, 44121 Ferrara, Italy.
Marzola E; Department of Chemical and Pharmaceutical Sciences, University of Ferrara, Via Luigi Borsari 46, 44121 Ferrara, Italy.
Neto JA; Department of Medical Sciences, Section of Pharmacology, University of Ferrara, Via Fossato di Mortara 17/19, 44121 Ferrara, Italy.
Ruzza C; Department of Medical Sciences, Section of Pharmacology, University of Ferrara, Via Fossato di Mortara 17/19, 44121 Ferrara, Italy.; LTTA Laboratory for Advanced Therapies, Technopole of Ferrara, Via Fossato di Mortara 70, 44121 Ferrara, Italy.
Calò G; Department of Medical Sciences, Section of Pharmacology, University of Ferrara, Via Fossato di Mortara 17/19, 44121 Ferrara, Italy.
Preti D; Department of Chemical and Pharmaceutical Sciences, University of Ferrara, Via Luigi Borsari 46, 44121 Ferrara, Italy.
Guerrini R; Department of Chemical and Pharmaceutical Sciences, University of Ferrara, Via Luigi Borsari 46, 44121 Ferrara, Italy.; LTTA Laboratory for Advanced Therapies, Technopole of Ferrara, Via Fossato di Mortara 70, 44121 Ferrara, Italy.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Oct 08; Vol. 63 (19), pp. 10782-10795. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Opioid Peptides/*pharmacology
Peptide Fragments/*agonists
Receptors, Opioid/*agonists
Animals ; GTP-Binding Proteins/chemistry ; Peptide Fragments/chemistry ; Receptors, Opioid/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
A Concise Review of Concepts in Opioid Pharmacology up to the Discovery of Endogenous Opioids.
Autorzy :
Cox BM; Department of Pharmacology and Molecular Therapeutics, Uniformed Services University, Bethesda, Maryland .
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2020 Oct; Vol. 98 (4), pp. 392-400. Date of Electronic Publication: 2020 Mar 31.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Opioid Peptides/*metabolism
Opioid-Related Disorders/*metabolism
Receptors, Opioid/*metabolism
Animals ; Congresses as Topic ; Humans ; International Cooperation ; Ligands
Czasopismo naukowe
Tytuł :
Recent Progress in Opioid Research from an Electrophysiological Perspective.
Autorzy :
Birdsong WT; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan (W.T.B.) and Vollum Institute, Oregon Health & Science University, Portland, Oregon (J.T.W.) .
Williams JT; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan (W.T.B.) and Vollum Institute, Oregon Health & Science University, Portland, Oregon (J.T.W.).
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2020 Oct; Vol. 98 (4), pp. 401-409. Date of Electronic Publication: 2020 Mar 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Brain/*physiology
Opioid Peptides/*metabolism
Opioid-Related Disorders/*physiopathology
Receptors, Opioid, mu/*metabolism
Animals ; Biomedical Research ; Electrophysiological Phenomena ; Humans ; Opioid-Related Disorders/metabolism ; Optogenetics ; Phosphorylation ; Receptors, Opioid, mu/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
IDE Degrades Nociceptin/Orphanin FQ through an Insulin Regulated Mechanism.
Autorzy :
Zingale GA; Department of Chemical Sciences, University of Catania, 95125 Catania, Italy.
Bellia F; Institute of Crystallography, National Research Council, 95126 Catania, Italy.
Ahmed IMM; Institute of Crystallography, National Research Council, 95126 Catania, Italy.
Mielczarek P; Maj Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, 31-343 Krakow, Poland.; Department of Biochemistry and Neurobiology, AGH University of Science and Technology, Mickiewicza Ave. 30, 30-059 Krakow, Poland.
Silberring J; Department of Biochemistry and Neurobiology, AGH University of Science and Technology, Mickiewicza Ave. 30, 30-059 Krakow, Poland.; Centre for Polymer and Carbon Materials, Polish Academy of Sciences, M.Curie-Sklodowskiej 34, 41-819 Zabrze, Poland.
Grasso G; Department of Chemical Sciences, University of Catania, 95125 Catania, Italy. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Sep 10; Vol. 20 (18). Date of Electronic Publication: 2019 Sep 10.
Typ publikacji :
Journal Article
MeSH Terms :
Insulin/*metabolism
Insulysin/*metabolism
Opioid Peptides/*metabolism
Spinal Cord/*metabolism
Amino Acid Sequence ; Animals ; Brain/drug effects ; Brain/metabolism ; Chromatography, Liquid/methods ; Insulin/chemistry ; Insulysin/antagonists & inhibitors ; Mass Spectrometry/methods ; Neuropeptides/chemistry ; Neuropeptides/metabolism ; Neuropeptides/pharmacology ; Opioid Peptides/chemistry ; Pain/prevention & control ; Pain Measurement/methods ; Peptide Fragments/chemistry ; Peptide Fragments/pharmacology ; Rats ; Receptor, Insulin/metabolism ; Spinal Cord/drug effects
Czasopismo naukowe
Tytuł :
Endogenous Neuropeptide Nocistatin Is a Direct Agonist of Acid-Sensing Ion Channels (ASIC1, ASIC2 and ASIC3).
Autorzy :
Osmakov DI; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia. .; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia. .
Koshelev SG; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Ivanov IA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Andreev YA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Kozlov SA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
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Źródło :
Biomolecules [Biomolecules] 2019 Aug 22; Vol. 9 (9). Date of Electronic Publication: 2019 Aug 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acid Sensing Ion Channels/*metabolism
Neuropeptides/*pharmacology
Opioid Peptides/*pharmacology
Sodium Channel Agonists/*pharmacology
Amino Acid Sequence ; Animals ; Neuropeptides/chemistry ; Opioid Peptides/chemistry ; Rats ; Sodium Channel Agonists/chemistry
Czasopismo naukowe
Tytuł :
Anticonvulsant evaluation and docking analysis of VV-Hemorphin-5 analogues.
Autorzy :
Todorov P; Department of Organic Chemistry, University of Chemical Technology and Metallurgy, Sofia, Bulgaria.
Rangelov M; Laboratory Chemistry and Biophysics of Proteins and Enzymes, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Peneva P; Department of Organic Chemistry, University of Chemical Technology and Metallurgy, Sofia, Bulgaria.
Todorova N; Department of Ecosystem Research, Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Tchekalarova J; Department of Behavioral Neurobiology, Institute of Neurobiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
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Źródło :
Drug development research [Drug Dev Res] 2019 Jun; Vol. 80 (4), pp. 425-437. Date of Electronic Publication: 2019 Jan 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anticonvulsants/*pharmacology
Hemoglobins/*pharmacology
Opioid Peptides/*pharmacology
Peptide Fragments/*pharmacology
Seizures/*drug therapy
Amino Acid Sequence ; Animals ; Anticonvulsants/chemical synthesis ; Anticonvulsants/chemistry ; Electroshock ; Hemoglobins/chemical synthesis ; Hemoglobins/chemistry ; Male ; Mice, Inbred ICR ; Molecular Docking Simulation ; Molecular Structure ; Opioid Peptides/chemical synthesis ; Opioid Peptides/chemistry ; Pentylenetetrazole ; Peptide Fragments/chemical synthesis ; Peptide Fragments/chemistry ; Protein Binding ; Psychomotor Performance/drug effects ; Receptors, Opioid, delta/metabolism ; Receptors, Opioid, kappa/metabolism ; Structure-Activity Relationship
Czasopismo naukowe

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