Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Optic Nerve Injuries"" wg kryterium: Temat


Tytuł:
Reduced Zn promotes retinal ganglion cells survival and optic nerve regeneration after injury through inhibiting autophagy mediated by ROS/Nrf2.
Autorzy:
Wu C; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Han J; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Wu S; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Liu C; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Zhang Q; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Tang J; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Liu Z; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Yang J; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Chen Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Zhuo Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China. Electronic address: .
Li Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China. Electronic address: .
Pokaż więcej
Źródło:
Free radical biology & medicine [Free Radic Biol Med] 2024 Feb 20; Vol. 212, pp. 415-432. Date of Electronic Publication: 2023 Dec 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Retinal Ganglion Cells*
Optic Nerve Injuries*/drug therapy
Optic Nerve Injuries*/genetics
Ethylenediamines*
Mice ; Animals ; NF-E2-Related Factor 2/genetics ; Reactive Oxygen Species ; Axons/physiology ; Nerve Regeneration ; Zinc ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Combined treatment of human mesenchymal stem cells and green tea extract on retinal ganglion cell regeneration in rats after optic nerve injury.
Autorzy:
Yang Q; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Xu Y; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Bin X; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Chan KP; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Chen S; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Qian Z; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Yao Y; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Yuan XL; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Qiu K; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Huang Y; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.
Ng TK; Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China. Electronic address: .
Pokaż więcej
Źródło:
Experimental eye research [Exp Eye Res] 2024 Feb; Vol. 239, pp. 109787. Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article
MeSH Terms:
Optic Nerve Injuries*/therapy
Optic Nerve Injuries*/metabolism
Mesenchymal Stem Cells*
Rats ; Humans ; Animals ; Retinal Ganglion Cells/metabolism ; Osteogenesis ; Tea/metabolism ; Nerve Regeneration/physiology ; Cell Survival/physiology ; Axons/metabolism
Czasopismo naukowe
Tytuł:
Factors predictive of poor visual outcome in indirect traumatic optic neuropathy: A retrospective cohort study.
Autorzy:
Srisombut T; Department of Surgery, Sawanpracharak Hospital, 3 Attakavee, Pak Nam Pho, Mueang Nakhon Sawan, Nakhon Sawan, 60000, Thailand.
Ittipanichpong P; Department of Ophthalmology, Sawanpracharak Hospital, 3 Attakavee, Pak Nam Pho, Mueang Nakhon Sawan, Nakhon Sawan, 60000, Thailand.
Arjkongharn N; Department of Ophthalmology, Rangsit University, Rajavithi Hospital, 2, Phaya Thai Rd, Thung Phaya Thai, Ratchathewi, 10400, Thailand.
Tangon D; Faculty of Medicine, Rangsit University, Rajavithi Hospital, 2, Phaya Thai Rd, Thung Phaya Thai, Ratchathewi, Bangkok, 10400, Thailand.
Kreesang R; Department of Surgery, Sawanpracharak Hospital, 3 Attakavee, Pak Nam Pho, Mueang Nakhon Sawan, Nakhon Sawan, 60000, Thailand.
Kemchoknatee P; Department of Ophthalmology, Rangsit University, Rajavithi Hospital, 2, Phaya Thai Rd, Thung Phaya Thai, Ratchathewi, 10400, Thailand. Electronic address: .
Pokaż więcej
Źródło:
Injury [Injury] 2024 Feb; Vol. 55 (2), pp. 111238. Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:
Journal Article
MeSH Terms:
Optic Nerve Injuries*/drug therapy
Optic Nerve Injuries*/etiology
Humans ; Male ; Adult ; Female ; Retrospective Studies ; Prognosis ; Visual Acuity ; Tomography, X-Ray Computed/adverse effects
Czasopismo naukowe
Tytuł:
Identification of circular RNA-Dcaf6 as a therapeutic target for optic nerve crush-induced RGC degeneration.
Autorzy:
Ji Y; Department of Ophthalmology and Optometry, The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; Department of Ophthalmology and Optometry, The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Li J; Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.
Liu S; Department of Ophthalmology and Optometry, The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; Department of Ophthalmology and Optometry, The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Zhu J; Department of Ophthalmology and Optometry, The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; Department of Ophthalmology and Optometry, The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Yao J; Department of Ophthalmology and Optometry, The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; Department of Ophthalmology and Optometry, The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China. Electronic address: .
Li KR; Department of Ophthalmology and Optometry, The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; Department of Ophthalmology and Optometry, The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China. Electronic address: .
Yan B; Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China; NHC Key Laboratory of Myopia Fudan University, Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China; Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University, Shanghai, China. Electronic address: .
Pokaż więcej
Źródło:
Genomics [Genomics] 2024 Jan; Vol. 116 (1), pp. 110776. Date of Electronic Publication: 2023 Dec 30.
Typ publikacji:
Journal Article
MeSH Terms:
Optic Nerve Injuries*/genetics
Optic Nerve Injuries*/drug therapy
Optic Nerve Injuries*/metabolism
RNA, Circular*/genetics
RNA, Circular*/metabolism
Animals ; Humans ; Disease Models, Animal ; Optic Nerve/metabolism ; Optic Nerve/pathology ; Retina ; Retinal Ganglion Cells/metabolism ; Retinal Ganglion Cells/pathology
Czasopismo naukowe
Tytuł:
Enriching new transplantable RGC-like cells from retinal organoids for RGC replacement therapy.
Autorzy:
Li G; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China. Electronic address: .
Luo Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Pokaż więcej
Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Mar 12; Vol. 700, pp. 149509. Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Journal Article
MeSH Terms:
Induced Pluripotent Stem Cells*
Optic Nerve Injuries*
Mice ; Animals ; Humans ; Retina ; Retinal Ganglion Cells ; Optic Nerve ; Organoids ; Disease Models, Animal ; Nerve Crush
Czasopismo naukowe
Tytuł:
Intercellular communication atlas reveals Oprm1 as a neuroprotective factor for retinal ganglion cells.
Autorzy:
Qian C; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Xin Y; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Qi C; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Wang H; Section on Light and Circadian Rhythms, National Institute of Mental Health, Bethesda, MD, USA.
Dong BC; Neuroscience Study Program, Krieger School of Arts & Sciences, Johns Hopkins University, Baltimore, MD, USA.
Zack DJ; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Blackshaw S; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Hattar S; Section on Light and Circadian Rhythms, National Institute of Mental Health, Bethesda, MD, USA.
Zhou FQ; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA. .; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA. .; Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China. .
Qian J; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. .
Pokaż więcej
Źródło:
Nature communications [Nat Commun] 2024 Mar 11; Vol. 15 (1), pp. 2206. Date of Electronic Publication: 2024 Mar 11.
Typ publikacji:
Journal Article
MeSH Terms:
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/metabolism
Optic Nerve Injuries*/metabolism
Animals ; Mice ; Cell Communication ; Cell Death ; Cell Survival ; Optic Nerve/metabolism ; Retinal Ganglion Cells/physiology
Czasopismo naukowe
Tytuł:
An effective pharmacological hydrogel induces optic nerve repair and improves visual function.
Autorzy:
Wang L; Department of Cell Biology, School of Basic Medical Sciences, Peking University Stem Cell Research Center, State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, 100191, China.; MOE Key Laboratory of Cell Proliferation and Differentiation, College of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, 100871, China.
Zhang S; Department of Cell Biology, School of Basic Medical Sciences, Peking University Stem Cell Research Center, State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, 100191, China.; MOE Key Laboratory of Cell Proliferation and Differentiation, College of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, 100871, China.
Han Y; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, 100871, China.
Tang S; Department of Cell Biology, School of Basic Medical Sciences, Peking University Stem Cell Research Center, State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, 100191, China.; MOE Key Laboratory of Cell Proliferation and Differentiation, College of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, 100871, China.
Li J; Department of Ophthalmology, Peking University People's Hospital Eye Diseases and Optometry Institute, Beijing, 100871, China.
Bu L; Department of Biomedical Informatics, School of Basic Medical Sciences, Peking University, Beijing, 100191, China.
Zhao D; Department of Biomedical Informatics, School of Basic Medical Sciences, Peking University, Beijing, 100191, China.
Deng H; Department of Cell Biology, School of Basic Medical Sciences, Peking University Stem Cell Research Center, State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, 100191, China. hongkui_.; MOE Key Laboratory of Cell Proliferation and Differentiation, College of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, 100871, China. hongkui_.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, 100871, China. hongkui_.; Changping Laboratory, Beijing, 102206, China. hongkui_.
Pokaż więcej
Źródło:
Science China. Life sciences [Sci China Life Sci] 2024 Mar; Vol. 67 (3), pp. 529-542. Date of Electronic Publication: 2023 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
Optic Nerve Injuries*/drug therapy
Glaucoma*/pathology
Mice ; Animals ; Hydrogels ; Optic Nerve/pathology ; Axons/physiology ; Disease Models, Animal ; Retinal Ganglion Cells/physiology ; Nerve Regeneration/physiology
Czasopismo naukowe
Tytuł:
BDNF and cAMP are neuroprotective in a porcine model of traumatic optic neuropathy.
Autorzy:
Heng K; Spencer Center for Vision Research, Byers Eye Institute, Department of Ophthalmology, School of Medicine, and.; Neurosciences Interdepartmental Program, Stanford University, Stanford, California, USA.
Young BK; Spencer Center for Vision Research, Byers Eye Institute, Department of Ophthalmology, School of Medicine, and.
Li B; Spencer Center for Vision Research, Byers Eye Institute, Department of Ophthalmology, School of Medicine, and.
Nies AD; Spencer Center for Vision Research, Byers Eye Institute, Department of Ophthalmology, School of Medicine, and.
Xia X; Spencer Center for Vision Research, Byers Eye Institute, Department of Ophthalmology, School of Medicine, and.
Wen RR; Spencer Center for Vision Research, Byers Eye Institute, Department of Ophthalmology, School of Medicine, and.
Dalal R; Spencer Center for Vision Research, Byers Eye Institute, Department of Ophthalmology, School of Medicine, and.
Bramblett GT; Clinical Rationale LLC, Austin, Texas, USA.
Holt AW; United States Army Institute of Surgical Research, Fort Sam Houston, Texas, USA.
Cleland JM; Department of Optometry, University of the Incarnate Word, San Antonio, Texas, USA.
Harris JN; United States Army Institute of Surgical Research, Fort Sam Houston, Texas, USA.
Wu AY; Spencer Center for Vision Research, Byers Eye Institute, Department of Ophthalmology, School of Medicine, and.
Goldberg JL; Spencer Center for Vision Research, Byers Eye Institute, Department of Ophthalmology, School of Medicine, and.
Pokaż więcej
Źródło:
JCI insight [JCI Insight] 2024 Feb 08; Vol. 9 (3). Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Brain-Derived Neurotrophic Factor*/metabolism
Optic Nerve Injuries*/drug therapy
Animals ; Swine ; Axons/metabolism ; Neuroprotection ; Nerve Regeneration ; Swine, Miniature/metabolism ; Vision Disorders
Czasopismo naukowe
Tytuł:
In vivo assessment of the ocular biomechanical properties in patients with idiopathic normal pressure hydrocephalus.
Autorzy:
Valsecchi N; Ophthalmology Unit, Dipartimento di Scienze Mediche e Chirurgiche, Alma Mater Studiorum, University of Bologna, Bologna, Italy. .; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. .
Roda M; Ophthalmology Unit, Dipartimento di Scienze Mediche e Chirurgiche, Alma Mater Studiorum, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Febbraro S; Ophthalmology Unit, Dipartimento di Scienze Mediche e Chirurgiche, Alma Mater Studiorum, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Trolli E; Ophthalmology Unit, Dipartimento di Scienze Mediche e Chirurgiche, Alma Mater Studiorum, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Palandri G; Unit of Neurosurgery, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Giannini G; Department of Biomedical and Neuromotor Sciences (DIBINEM), IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Milletti D; Unit of Rehabilitation Medicine, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Schiavi C; Ophthalmology Unit, Dipartimento di Scienze Mediche e Chirurgiche, Alma Mater Studiorum, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Fontana L; Ophthalmology Unit, Dipartimento di Scienze Mediche e Chirurgiche, Alma Mater Studiorum, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Pokaż więcej
Źródło:
International ophthalmology [Int Ophthalmol] 2024 Feb 02; Vol. 44 (1), pp. 1. Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Glaucoma, Open-Angle*
Hydrocephalus, Normal Pressure*/complications
Optic Nerve Injuries*
Humans ; Intraocular Pressure ; Tonometry, Ocular/methods ; Cornea/physiology ; Biomechanical Phenomena ; Elasticity
Czasopismo naukowe
Tytuł:
TRPV: An emerging target in glaucoma and optic nerve damage.
Autorzy:
Zhang X; Department of Ophthalmology, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, China.
Wang F; Department of Ophthalmology, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, China. Electronic address: .
Su Y; Eye Hospital, The First Affiliated Hospital, Harbin Medical University, Harbin, China. Electronic address: .
Pokaż więcej
Źródło:
Experimental eye research [Exp Eye Res] 2024 Feb; Vol. 239, pp. 109784. Date of Electronic Publication: 2024 Jan 08.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Glaucoma*
Optic Nerve Injuries*/metabolism
Humans ; Sclera/pathology ; Retina/pathology ; Trabecular Meshwork/metabolism ; Optic Nerve/pathology
Czasopismo naukowe
Tytuł:
Model matters: Differential outcomes in traumatic optic neuropathy pathophysiology between blunt and blast-wave mediated head injuries.
Autorzy:
Hetzer SM; Neuroscience Graduate Program, University of Cincinnati College of Medicine, United States of America. Electronic address: .
O'Connell C; Division of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati, United States of America.
Lallo V; College of Arts and Sciences, University of Cincinnati, United States of America.
Robson M; Division of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati, United States of America.
Evanson NK; Department of Pediatrics, University of Cincinnati College of Medicine, United States of America; Division of Pediatric Rehabilitation Medicine, Cincinnati Children's Hospital Medical Center, United States of America.
Pokaż więcej
Źródło:
Experimental neurology [Exp Neurol] 2024 Feb; Vol. 372, pp. 114613. Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Optic Nerve Injuries*/pathology
Blast Injuries*/complications
Blast Injuries*/pathology
Brain Injuries, Traumatic*/complications
Brain Injuries, Traumatic*/pathology
Wounds, Nonpenetrating*/complications
Humans ; Male ; Mice ; Animals ; Optic Nerve/pathology ; Amyloid beta-Protein Precursor
Czasopismo naukowe
Tytuł:
Induced Attenuation of Scleral TGF-β Signaling in Mutant Mice Increases Susceptibility to IOP-Induced Optic Nerve Damage.
Autorzy:
Gebert M; Institute of Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany.
Heimbucher J; Institute of Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany.
Gsell VK; Institute of Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany.
Keimer K; Institute of Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany.
Dillinger AE; Institute of Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany.
Tamm ER; Institute of Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany.
Pokaż więcej
Źródło:
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2024 Jan 02; Vol. 65 (1), pp. 48.
Typ publikacji:
Journal Article
MeSH Terms:
Optic Disk*
Glaucoma*
Optic Nerve Injuries*
Animals ; Mice ; Sclera ; Tamoxifen ; Transforming Growth Factor beta/genetics
Czasopismo naukowe
Tytuł:
Histone methyltransferase Ezh2 coordinates mammalian axon regeneration via regulation of key regenerative pathways.
Autorzy:
Wang XW; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Molecular Medicine, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
Yang SG; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Hu MW; Department of Ophthalmology and.
Wang RY; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Zhang C; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Kosanam AR; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Ochuba AJ; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jiang JJ; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Luo X; Department of Ophthalmology and.
Guan Y; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Qian J; Department of Ophthalmology and.
Liu CM; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Zhou FQ; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Pokaż więcej
Źródło:
The Journal of clinical investigation [J Clin Invest] 2023 Nov 28; Vol. 134 (3). Date of Electronic Publication: 2023 Nov 28 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Axons*/metabolism
Optic Nerve Injuries*/genetics
Optic Nerve Injuries*/metabolism
Animals ; Mice ; Ganglia, Spinal/metabolism ; Mammals ; Nerve Regeneration/genetics ; Retinal Ganglion Cells/metabolism
Czasopismo naukowe
Tytuł:
Neuroinflammation and gliosis in the injured and contralateral retinas after unilateral optic nerve crush.
Autorzy:
Cabrera-Maqueda JM; Grupo de Oftalmología Experimental, Departamento de Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica, Facultad de Medicina, Universidad de Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), Campus de Ciencias de la Salud, 30120, Murcia, Spain; Center of Neuroimmunology, Service of Neurology, Laboratory of Advanced Imaging in Neuroimmunological Diseases, Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.
Boia R; University of Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, Coimbra, Portugal; University of Coimbra, Center for Innovative Biomedicine and Biotechnology (CIBB), Coimbra, Portugal; Clinical Academic Center of Coimbra (CACC), Coimbra, Portugal.
Lucas-Ruiz F; Grupo de Oftalmología Experimental, Departamento de Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica, Facultad de Medicina, Universidad de Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), Campus de Ciencias de la Salud, 30120, Murcia, Spain.
González-Riquelme MJ; Grupo de Oftalmología Experimental, Departamento de Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica, Facultad de Medicina, Universidad de Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), Campus de Ciencias de la Salud, 30120, Murcia, Spain.
Ambrósio AF; University of Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, Coimbra, Portugal; University of Coimbra, Center for Innovative Biomedicine and Biotechnology (CIBB), Coimbra, Portugal; Clinical Academic Center of Coimbra (CACC), Coimbra, Portugal; Association for Innovation and Biomedical Research on Light and Image (AIBILI), Coimbra, Portugal.
Santiago AR; University of Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, Coimbra, Portugal; University of Coimbra, Center for Innovative Biomedicine and Biotechnology (CIBB), Coimbra, Portugal; Clinical Academic Center of Coimbra (CACC), Coimbra, Portugal; Association for Innovation and Biomedical Research on Light and Image (AIBILI), Coimbra, Portugal; University of Coimbra, Institute of Immunology, Faculty of Medicine, Coimbra, Portugal.
Vidal-Sanz M; Grupo de Oftalmología Experimental, Departamento de Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica, Facultad de Medicina, Universidad de Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), Campus de Ciencias de la Salud, 30120, Murcia, Spain.
Agudo-Barriuso M; Grupo de Oftalmología Experimental, Departamento de Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica, Facultad de Medicina, Universidad de Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), Campus de Ciencias de la Salud, 30120, Murcia, Spain. Electronic address: .
Galindo-Romero C; Grupo de Oftalmología Experimental, Departamento de Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica, Facultad de Medicina, Universidad de Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), Campus de Ciencias de la Salud, 30120, Murcia, Spain. Electronic address: .
Pokaż więcej
Źródło:
Experimental eye research [Exp Eye Res] 2023 Oct; Vol. 235, pp. 109627. Date of Electronic Publication: 2023 Aug 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Transforming Growth Factor beta1*/pharmacology
Optic Nerve Injuries*/genetics
Optic Nerve Injuries*/metabolism
Mice ; Animals ; Retinal Ganglion Cells/metabolism ; Gliosis/metabolism ; Neuroinflammatory Diseases ; Tumor Necrosis Factor-alpha/metabolism ; Mice, Inbred C57BL ; Retina/metabolism ; Optic Nerve/metabolism ; Nerve Crush/methods
Czasopismo naukowe
Tytuł:
Type I Collagen-Adhesive and ROS-Scavenging Nanoreactors Enhanced Retinal Ganglion Cell Survival in an Experimental Optic Nerve Crush Model.
Autorzy:
Du Y; Key Laboratory of Functional Polymer Materials of Ministry of Education, State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin, 300071, China.
Cai M; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, 300020, China.; Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin Eye Hospital, Tianjin, 300020, China.
Mu J; Aier Eye Institute, Changsha, 410015, China.; Tianjin Aier Eye Hospital, Tianjin, 300190, China.
Li X; Key Laboratory of Functional Polymer Materials of Ministry of Education, State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin, 300071, China.
Song Y; Key Laboratory of Functional Polymer Materials of Ministry of Education, State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin, 300071, China.
Yuan X; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, 300020, China.; Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin Eye Hospital, Tianjin, 300020, China.
Hua X; Aier Eye Institute, Changsha, 410015, China.; Tianjin Aier Eye Hospital, Tianjin, 300190, China.
Guo S; Key Laboratory of Functional Polymer Materials of Ministry of Education, State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin, 300071, China.
Pokaż więcej
Źródło:
Macromolecular rapid communications [Macromol Rapid Commun] 2023 Dec; Vol. 44 (23), pp. e2300389. Date of Electronic Publication: 2023 Sep 17.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Ganglion Cells*/metabolism
Optic Nerve Injuries*/metabolism
Rats ; Animals ; Collagen Type I/metabolism ; Reactive Oxygen Species/metabolism ; Optic Nerve/metabolism ; Nanotechnology ; Cell Survival ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Comparison of the Biomechanics of the Mouse Astrocytic Lamina Cribrosa Between Glaucoma and Optic Nerve Crush Models.
Autorzy:
Korneva A; Glaucoma Center of Excellence, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Kimball EC; Glaucoma Center of Excellence, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Johnson TV; Glaucoma Center of Excellence, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Quillen SE; Glaucoma Center of Excellence, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Pease ME; Glaucoma Center of Excellence, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Quigley HA; Glaucoma Center of Excellence, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Nguyen TD; Glaucoma Center of Excellence, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.; Department of Mechanical Engineering, The Johns Hopkins University, Baltimore, Maryland, United States.
Pokaż więcej
Źródło:
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2023 Dec 01; Vol. 64 (15), pp. 14.
Typ publikacji:
Journal Article
MeSH Terms:
Glaucoma*
Optic Nerve Injuries*
Mice ; Animals ; Biomechanical Phenomena ; Intraocular Pressure ; Optic Nerve ; Sclera
Czasopismo naukowe
Tytuł:
Park7 protects retinal ganglion cells and promotes functional preservation after optic nerve crush via regulation of the Nrf2 signaling pathway.
Autorzy:
Ouyang L; Department of Ophthalmology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, 430060, Hubei, China.
He T; Department of Ophthalmology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, 430060, Hubei, China.
Xing Y; Department of Ophthalmology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, 430060, Hubei, China. yiqiao_.
Pokaż więcej
Źródło:
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie [Graefes Arch Clin Exp Ophthalmol] 2023 Dec; Vol. 261 (12), pp. 3489-3502. Date of Electronic Publication: 2023 May 18.
Typ publikacji:
Journal Article
MeSH Terms:
Optic Nerve Injuries*
Retinal Ganglion Cells*
Animals ; Male ; Mice ; Disease Models, Animal ; Kelch-Like ECH-Associated Protein 1/metabolism ; Mice, Inbred C57BL ; Nerve Crush ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; NF-E2-Related Factor 2/pharmacology ; Optic Nerve/metabolism ; RNA, Small Interfering/metabolism ; RNA, Small Interfering/pharmacology ; Signal Transduction
Czasopismo naukowe
Tytuł:
The GPR84 molecule is a mediator of a subpopulation of retinal microglia that promote TNF/IL-1α expression via the rho-ROCK pathway after optic nerve injury.
Autorzy:
Sato K; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Advanced Ophthalmic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Ohno-Oishi M; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Advanced Ophthalmic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Yoshida M; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Sato T; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Aizawa T; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Sasaki Y; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Maekawa S; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Ishikawa M; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Ophthalmic Imaging and Information Analytics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Omodaka K; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Ophthalmic Imaging and Information Analytics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kawano C; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Ohue-Kitano R; Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.; Laboratory of Molecular Neurobiology, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
Kimura I; Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.; Laboratory of Molecular Neurobiology, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
Nakazawa T; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Advanced Ophthalmic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Ophthalmic Imaging and Information Analytics, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Retinal Disease Control, Tohoku University Graduate School of Medicine, Sendai, Japan.
Pokaż więcej
Źródło:
Glia [Glia] 2023 Nov; Vol. 71 (11), pp. 2609-2622. Date of Electronic Publication: 2023 Jul 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Optic Nerve Injuries*
Mice ; Animals ; Microglia/metabolism ; Retinal Ganglion Cells ; rho-Associated Kinases/metabolism ; Neuroglia/metabolism ; Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/metabolism
Czasopismo naukowe
Tytuł:
Diversity in homeostatic calcium set points predicts retinal ganglion cell survival following optic nerve injury in vivo.
Autorzy:
McCracken S; John F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA; Graduate Program in Neuroscience, Washington University School of Medicine, St. Louis, MO 63110, USA.
Fitzpatrick MJ; John F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA; Graduate Program in Neuroscience, Washington University School of Medicine, St. Louis, MO 63110, USA; Medical Scientist Training Program, Washington University School of Medicine, St. Louis, MO 63110, USA.
Hall AL; John F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA; Postbaccalaureate Program in Developmental Biology & Regenerative Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Wang Z; John F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA; Graduate Program in Neuroscience, Washington University School of Medicine, St. Louis, MO 63110, USA; Medical Scientist Training Program, Washington University School of Medicine, St. Louis, MO 63110, USA.
Kerschensteiner D; John F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Biomedical Engineering, Washington University School of Medicine, St. Louis, MO 63110, USA.
Morgan JL; John F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO 63110, USA.
Williams PR; John F. Hardesty, MD Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: .
Pokaż więcej
Źródło:
Cell reports [Cell Rep] 2023 Oct 31; Vol. 42 (10), pp. 113165. Date of Electronic Publication: 2023 Sep 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Optic Nerve Injuries*/metabolism
Humans ; Animals ; Retinal Ganglion Cells/metabolism ; Calcium/metabolism ; Axons/metabolism ; Optic Nerve/metabolism ; Cell Survival ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Contralateral Astrocyte Response to Acute Optic Nerve Damage Is Mitigated by PANX1 Channel Activity.
Autorzy:
Wurl JA; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA.
Mac Nair CE; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA.
Dietz JA; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA.
Shestopalov VI; Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL 33136, USA.
Nickells RW; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA.; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI 53705, USA.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 27; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 27.
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes*/metabolism
Optic Nerve Injuries*/metabolism
Mice ; Animals ; Neuroglia/metabolism ; Retina/metabolism ; Optic Nerve/pathology ; Glial Fibrillary Acidic Protein/metabolism ; Nerve Tissue Proteins/metabolism ; Connexins/metabolism
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies