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Wyszukujesz frazę ""Organ Culture Techniques"" wg kryterium: Temat


Tytuł :
Organotypic-liver slide culture systems to explore the role of extracellular vesicles in pancreatic cancer metastatic behavior and guide new therapeutic approaches.
Autorzy :
Supadmanaba IGP; Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Department of Pathology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Biochemistry Department, Faculty of Medicine, Universitas Udayana, Denpasar, Bali, Indonesia.
Comandatore A; Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; General Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Morelli L; General Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Giovannetti E; Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Cancer Pharmacology Lab, AIRC Start-Up Unit, Fondazione Pisana per La Scienza, Pisa, Italy.
Lagerweij T; Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Department of Pathology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
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Źródło :
Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2021 Aug; Vol. 17 (8), pp. 937-946. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Models, Biological*
Organ Culture Techniques*
Pancreatic Neoplasms/*pathology
Animals ; Extracellular Vesicles/metabolism ; Humans ; Liver/cytology ; Neoplasm Metastasis ; Pancreatic Neoplasms/therapy
Czasopismo naukowe
Tytuł :
Derivation of Adult Human Cortical Organotypic Slice Cultures for Coculture with Reprogrammed Neuronal Cells.
Autorzy :
Kvist G; Lund Stem Cell Center, Lund University, Lund, Sweden. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2352, pp. 253-259.
Typ publikacji :
Journal Article
MeSH Terms :
Cellular Reprogramming*
Cellular Reprogramming Techniques*
Coculture Techniques*
Organ Culture Techniques*
Cerebral Cortex/*cytology
Neurons/*cytology
Neurons/*metabolism
Cell Culture Techniques ; Humans
Czasopismo naukowe
Tytuł :
SARS-CoV-2 replicates in respiratory ex vivo organ cultures of domestic ruminant species.
Autorzy :
Di Teodoro G; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Valleriani F; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Puglia I; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Monaco F; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Di Pancrazio C; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Luciani M; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Krasteva I; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Petrini A; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Marcacci M; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy; Department of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy.
D'Alterio N; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Curini V; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Iorio M; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Migliorati G; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Di Domenico M; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Morelli D; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Calistri P; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Savini G; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy.
Decaro N; Department of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy.
Holmes EC; Marie Bashir Institute for Infectious Diseases and Biosecurity, School of Life and Environmental Sciences and School of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia.
Lorusso A; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise, Teramo, Italy. Electronic address: .
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Źródło :
Veterinary microbiology [Vet Microbiol] 2021 Jan; Vol. 252, pp. 108933. Date of Electronic Publication: 2020 Nov 24.
Typ publikacji :
Journal Article
MeSH Terms :
Organ Culture Techniques*
Viral Tropism*
Virus Replication*
Respiratory System/*virology
Ruminants/*virology
SARS-CoV-2/*physiology
Angiotensin-Converting Enzyme 2/genetics ; Animals ; Cattle/virology ; Host Specificity ; SARS-CoV-2/genetics ; Sheep/virology ; Swine/virology
Czasopismo naukowe
Tytuł :
Human Organs-on-Chips for Virology.
Autorzy :
Tang H; Medical Systems Biophysics and Bioengineering, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, 2333 CC, Leiden, The Netherlands.
Abouleila Y; Medical Systems Biophysics and Bioengineering, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, 2333 CC, Leiden, The Netherlands.
Si L; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA 02115, USA.
Ortega-Prieto AM; Section of Virology, Department of Medicine, Imperial College London, London, W2 1PG, UK.
Mummery CL; Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, 2333 ZD, Leiden, The Netherlands.
Ingber DE; Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA 02115, USA; Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA; Vascular Biology Program and Department of Surgery, Harvard Medical School and Boston Children's Hospital, Boston, MA 02115, USA.
Mashaghi A; Medical Systems Biophysics and Bioengineering, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, 2333 CC, Leiden, The Netherlands. Electronic address: .
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Źródło :
Trends in microbiology [Trends Microbiol] 2020 Nov; Vol. 28 (11), pp. 934-946. Date of Electronic Publication: 2020 Jul 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Virus Physiological Phenomena*
Microfluidics/*methods
Organ Culture Techniques/*methods
Virology/*methods
Virus Diseases/*virology
Animals ; Humans ; Microfluidics/instrumentation ; Organ Culture Techniques/instrumentation ; Virology/instrumentation ; Viruses/genetics
Czasopismo naukowe
Tytuł :
Transcriptome analysis reveals inadequate spermatogenesis and immediate radical immune reactions during organ culture in vitro spermatogenesis.
Autorzy :
Abe T; Biopharmaceutical and Regenerative Sciences, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Kanagawa, Japan; Laboratory for Cellular Function Conversion Technology, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan.
Nishimura H; Laboratory for Cellular Function Conversion Technology, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan.
Sato T; Biopharmaceutical and Regenerative Sciences, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Kanagawa, Japan.
Suzuki H; Laboratory for Cellular Function Conversion Technology, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan.
Ogawa T; Biopharmaceutical and Regenerative Sciences, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Kanagawa, Japan. Electronic address: .
Suzuki T; Laboratory for Cellular Function Conversion Technology, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan; Functional Genomics, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Kanagawa, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Oct 01; Vol. 530 (4), pp. 732-738. Date of Electronic Publication: 2020 Aug 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity, Innate*
Organ Culture Techniques*/methods
Spermatogenesis*
Testis*/cytology
Testis*/immunology
Testis*/metabolism
Transcriptome*
Animals ; Female ; Gene Expression Profiling ; Male ; Meiosis ; Mice, Inbred C57BL ; Mice, Inbred ICR ; Mice, Transgenic ; NF-kappa B/genetics ; NF-kappa B/immunology ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/immunology
Czasopismo naukowe
Tytuł :
Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids.
Autorzy :
Cho AN; Department of Biotechnology, Yonsei University, Seoul, Republic of Korea.
Jin Y; Department of Biotechnology, Yonsei University, Seoul, Republic of Korea.
An Y; Department of Biotechnology, Yonsei University, Seoul, Republic of Korea.
Kim J; Department of Biotechnology, Yonsei University, Seoul, Republic of Korea.
Choi YS; Department of Biotechnology, Yonsei University, Seoul, Republic of Korea.
Lee JS; Department of Biotechnology, Yonsei University, Seoul, Republic of Korea.
Kim J; Department of Biotechnology, Yonsei University, Seoul, Republic of Korea.
Choi WY; Department of Biochemistry, Yonsei University, Seoul, Republic of Korea.
Koo DJ; Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Republic of Korea.
Yu W; Signature Program in Neuroscience and Behavioral Disorders, Duke-NUS Medical School, Singapore, Singapore.
Chang GE; Department of Biotechnology, Yonsei University, Seoul, Republic of Korea.
Kim DY; Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Republic of Korea.
Jo SH; Department of Chemical Engineering, Soongsil University, Seoul, Republic of Korea.
Kim J; Division of Pediatric Neurology, Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim SY; Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Republic of Korea.; Department of Chemistry, Seoul National University, Seoul, Republic of Korea.
Kim YG; Department of Chemical Engineering, Soongsil University, Seoul, Republic of Korea.
Kim JY; Department of Advanced Materials Engineering, Kangwon National University, Samcheok, Republic of Korea.
Choi N; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
Cheong E; Department of Biotechnology, Yonsei University, Seoul, Republic of Korea.
Kim YJ; Department of Biochemistry, Yonsei University, Seoul, Republic of Korea.
Je HS; Signature Program in Neuroscience and Behavioral Disorders, Duke-NUS Medical School, Singapore, Singapore.
Kang HC; Division of Pediatric Neurology, Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Cho SW; Department of Biotechnology, Yonsei University, Seoul, Republic of Korea. .; Center for Nanomedicine, Institute for Basic science (IBS), Seoul, Republic of Korea. .; Graduate Program of Nano Biomedical Engineering (NanoBME), Advanced Science Institute, Yonsei University, Seoul, Republic of Korea. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 05; Vol. 12 (1), pp. 4730. Date of Electronic Publication: 2021 Aug 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lab-On-A-Chip Devices*
Brain/*growth & development
Brain/*physiology
Neurogenesis/*physiology
Organoids/*growth & development
Organoids/*physiology
Animals ; Brain/cytology ; Culture Media ; Electrophysiological Phenomena ; Extracellular Matrix/physiology ; Feasibility Studies ; Gene Expression Profiling ; Humans ; Hydrogels ; Induced Pluripotent Stem Cells/cytology ; Induced Pluripotent Stem Cells/physiology ; Models, Anatomic ; Models, Neurological ; Neurogenesis/genetics ; Neuroglia/cytology ; Neuroglia/physiology ; Organ Culture Techniques/instrumentation ; Organ Culture Techniques/methods ; Organoids/cytology ; Swine
Czasopismo naukowe
Tytuł :
Evidence of an antidepressant-like effect of xylopic acid mediated by serotonergic mechanisms.
Autorzy :
Biney RP; Department of Pharmacology, School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana. .; School of Pharmacy and Pharmaceutical Sciences, University of Cape Coast, Cape Coast, Ghana. .
Benneh CK; Department of Pharmacology and Toxicology, School of Pharmacy, University of Health and Allied Sciences, Ho, Ghana.
Adongo DW; Department of Pharmacology and Toxicology, School of Pharmacy, University of Health and Allied Sciences, Ho, Ghana.
Ameyaw EO; School of Pharmacy and Pharmaceutical Sciences, University of Cape Coast, Cape Coast, Ghana.
Woode E; Department of Pharmacology and Toxicology, School of Pharmacy, University of Health and Allied Sciences, Ho, Ghana.; Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2021 Aug; Vol. 238 (8), pp. 2105-2120. Date of Electronic Publication: 2021 Apr 10.
Typ publikacji :
Journal Article
MeSH Terms :
Antidepressive Agents/*therapeutic use
Brain/*drug effects
Brain/*metabolism
Depression/*drug therapy
Diterpenes, Kaurane/*therapeutic use
Serotonin/*metabolism
Animals ; Antidepressive Agents/pharmacology ; Depression/metabolism ; Depression/psychology ; Diterpenes, Kaurane/pharmacology ; Dose-Response Relationship, Drug ; Hindlimb Suspension/adverse effects ; Hindlimb Suspension/psychology ; Male ; Mice ; Mice, Inbred ICR ; Monoamine Oxidase/metabolism ; Monoamine Oxidase Inhibitors/pharmacology ; Organ Culture Techniques ; Rats ; Rats, Sprague-Dawley ; Serotonin Antagonists/pharmacology ; Serotonin Antagonists/therapeutic use ; Swimming/psychology ; Zebrafish
Czasopismo naukowe
Tytuł :
Immunotherapy response modeling by ex-vivo organ culture for lung cancer.
Autorzy :
Kamer I; Institute of Oncology, Sheba Medical Center, Tel Hashomer, 52620000, Ramat Gan, Israel.
Bab-Dinitz E; Institute of Oncology, Sheba Medical Center, Tel Hashomer, 52620000, Ramat Gan, Israel.
Zadok O; Institute of Oncology, Sheba Medical Center, Tel Hashomer, 52620000, Ramat Gan, Israel.
Ofek E; Pathology Department, Sheba Medical Center, Ramat Gan, Israel.
Gottfried T; Institute of Oncology, Sheba Medical Center, Tel Hashomer, 52620000, Ramat Gan, Israel.
Daniel-Meshulam I; Institute of Oncology, Sheba Medical Center, Tel Hashomer, 52620000, Ramat Gan, Israel.
Hout-Siloni G; Pathology Department, Sheba Medical Center, Ramat Gan, Israel.
Ben Nun A; Thoracic Surgery Department, Sheba Medical Center, Ramat Gan, Israel.; Affiliated with Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.; Thoracic Surgery Department, Assuta Medical Center, Tel Aviv, Israel.
Barshack I; Pathology Department, Sheba Medical Center, Ramat Gan, Israel.; Affiliated with Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Onn A; Pulmonology Institute, Sheba Medical Center, Ramat Gan, Israel.; Affiliated with Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Bar J; Institute of Oncology, Sheba Medical Center, Tel Hashomer, 52620000, Ramat Gan, Israel. .; Affiliated with Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2021 Aug; Vol. 70 (8), pp. 2223-2234. Date of Electronic Publication: 2021 Jan 23.
Typ publikacji :
Journal Article
MeSH Terms :
Lung Neoplasms/*immunology
Lung Neoplasms/*therapy
B7-H1 Antigen/immunology ; Biomarkers, Tumor/immunology ; CD4 Antigens/immunology ; CD8 Antigens/immunology ; CTLA-4 Antigen/immunology ; Carcinoma, Non-Small-Cell Lung/immunology ; Carcinoma, Non-Small-Cell Lung/therapy ; Forkhead Transcription Factors/immunology ; Humans ; Immunohistochemistry/methods ; Immunologic Factors/immunology ; Immunotherapy/methods ; Interferon-gamma/immunology ; Organ Culture Techniques/methods ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł :
The Use of Stem Cell-Derived Organoids in Disease Modeling: An Update.
Autorzy :
Azar J; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut 1107 2260, Lebanon.
Bahmad HF; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut 1107 2260, Lebanon.; Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL 33140, USA.
Daher D; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut 1107 2260, Lebanon.
Moubarak MM; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut 1107 2260, Lebanon.
Hadadeh O; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut 1107 2260, Lebanon.
Monzer A; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut 1107 2260, Lebanon.
Al Bitar S; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut 1107 2260, Lebanon.
Jamal M; Hamdan Bin Mohammed College of Dental Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai 66566, United Arab Emirates.
Al-Sayegh M; Biology Division, New York University Abu Dhabi, Abu Dhabi 2460, United Arab Emirates.
Abou-Kheir W; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut 1107 2260, Lebanon.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 17; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Evaluation, Preclinical/*methods
Organ Culture Techniques/*methods
Organoids/*cytology
Pluripotent Stem Cells/*cytology
Animals ; Humans ; Models, Biological ; Organoids/drug effects ; Organoids/metabolism ; Pluripotent Stem Cells/drug effects ; Pluripotent Stem Cells/metabolism
Czasopismo naukowe
Tytuł :
Downregulated expression of intestinal P-glycoprotein in rats with cisplatin-induced acute kidney injury causes amplification of its transport capacity to maintain "gatekeeper" function.
Autorzy :
Takeda F; Department of Pharmaceutics, School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Oda M; Department of Pharmaceutics, School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Terasaki M; Department of Health and Environmental Sciences, School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Ichimura Y; Department of Pharmaceutics, School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Kojima H; Department of Health and Environmental Sciences, School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Saitoh H; Department of Pharmaceutics, School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Jul 15; Vol. 423, pp. 115570. Date of Electronic Publication: 2021 May 07.
Typ publikacji :
Journal Article
MeSH Terms :
ATP Binding Cassette Transporter, Subfamily B, Member 1/*biosynthesis
Acute Kidney Injury/*chemically induced
Acute Kidney Injury/*metabolism
Cisplatin/*toxicity
Intestine, Small/*drug effects
Intestine, Small/*metabolism
ATP Binding Cassette Transporter, Subfamily B, Member 1/antagonists & inhibitors ; ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 2/biosynthesis ; ATP Binding Cassette Transporter, Subfamily G, Member 2/genetics ; Acute Kidney Injury/genetics ; Animals ; Antineoplastic Agents/toxicity ; Down-Regulation/drug effects ; Down-Regulation/physiology ; Gene Expression ; Male ; Organ Culture Techniques ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Anti-inflammatory and tight junction protective activity of the herbal preparation STW 5-II on mouse intestinal organoids.
Autorzy :
Elbadawi M; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany.
Ammar RM; Bayer Consumer Health, Steigerwald Arzneimittelwerk GmbH, Darmstadt, Germany.
Aziz-Kalbhenn H; Bayer Consumer Health, Steigerwald Arzneimittelwerk GmbH, Darmstadt, Germany.
Rabini S; Bayer Consumer Health, Steigerwald Arzneimittelwerk GmbH, Darmstadt, Germany.
Klauck SM; Division of Cancer Genome Research, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), National Center for Tumor Diseases (NCT), Heidelberg, Germany.
Dawood M; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany; Department of Molecular Biology, Faculty of Medical Laboratory Science, Al-Neelain University, Khartoum, Sudan.
Saeed MEM; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany.
Kampf CJ; Department of Chemistry, Johannes Gutenberg University, Mainz, Germany.
Efferth T; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Jul 15; Vol. 88, pp. 153589. Date of Electronic Publication: 2021 May 06.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Intestines/*drug effects
Irritable Bowel Syndrome/*drug therapy
Plant Extracts/*pharmacology
Tight Junctions/*drug effects
Animals ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/metabolism ; Computer Simulation ; Disease Models, Animal ; Gene Expression Regulation/drug effects ; Inflammation Mediators/metabolism ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/metabolism ; Irritable Bowel Syndrome/etiology ; Mice ; NF-kappa B/metabolism ; Organ Culture Techniques ; Organoids/metabolism ; Organoids/physiopathology ; Plant Extracts/chemistry ; STAT1 Transcription Factor/metabolism ; Tight Junctions/metabolism ; Zonula Occludens-1 Protein/metabolism
Czasopismo naukowe
Tytuł :
How to Obtain a Mega-Intestine with Normal Morphology: In Silico Modelling of Postnatal Intestinal Growth in a Cd97-Transgenic Mouse.
Autorzy :
Hofmann F; Research Laboratories, Department of Surgery, Leipzig University, 04107 Leipzig, Germany.
Thalheim T; Interdisciplinary Institute for Bioinformatics (IZBI), Leipzig University, 04107 Leipzig, Germany.
Rother K; Research Laboratories, Department of Surgery, Leipzig University, 04107 Leipzig, Germany.; Interdisciplinary Institute for Bioinformatics (IZBI), Leipzig University, 04107 Leipzig, Germany.
Quaas M; Research Laboratories, Department of Surgery, Leipzig University, 04107 Leipzig, Germany.
Kerner C; Research Laboratories, Department of Surgery, Leipzig University, 04107 Leipzig, Germany.
Przybilla J; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Leipzig University, 04107 Leipzig, Germany.
Aust G; Research Laboratories, Department of Surgery, Leipzig University, 04107 Leipzig, Germany.
Galle J; Interdisciplinary Institute for Bioinformatics (IZBI), Leipzig University, 04107 Leipzig, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 08; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Models, Biological*
Intestinal Mucosa/*growth & development
Intestine, Small/*growth & development
Receptors, G-Protein-Coupled/*metabolism
Stem Cells/*metabolism
Animals ; Mice ; Mice, Transgenic ; Organ Culture Techniques ; Receptors, G-Protein-Coupled/genetics
Czasopismo naukowe
Tytuł :
Development of Feline Ileum- and Colon-Derived Organoids and Their Potential Use to Support Feline Coronavirus Infection.
Autorzy :
Tekes G; Institute of Virology, Justus Liebig University Giessen, 35390 Giessen, Germany.
Ehmann R; Bundeswehr Institute of Microbiology, 80937 Munich, Germany.
Boulant S; Department of Infectious Diseases, Virology, Heidelberg University Hospital, 69120 Heidelberg, Germany.; Research Group 'Cellular Polarity and Viral Infection', German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Stanifer ML; Department of Infectious Diseases, Molecular Virology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
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Źródło :
Cells [Cells] 2020 Sep 12; Vol. 9 (9). Date of Electronic Publication: 2020 Sep 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus, Feline/*growth & development
Feline Infectious Peritonitis/*pathology
Organ Culture Techniques/*veterinary
Organoids/*growth & development
Animals ; Cats ; Cell Line ; Colon/cytology ; Colon/virology ; Coronavirus, Feline/genetics ; Female ; HEK293 Cells ; Humans ; Ileum/cytology ; Ileum/virology ; Models, Biological ; Organ Culture Techniques/methods ; Organoids/cytology
Czasopismo naukowe
Tytuł :
Ex vivo model of herpes simplex virus type I dendritic and geographic keratitis using a corneal active storage machine.
Autorzy :
Courrier E; Corneal Graft Biology, Engineering and Imaging Laboratory, Health Innovation Campus, Faculty of Medicine, Jean Monnet University, Saint-Etienne, France.
Maurin C; Corneal Graft Biology, Engineering and Imaging Laboratory, Health Innovation Campus, Faculty of Medicine, Jean Monnet University, Saint-Etienne, France.
Lambert V; Department of Ophthalmology, University Hospital, Saint-Etienne, France.
Renault D; Corneal Graft Biology, Engineering and Imaging Laboratory, Health Innovation Campus, Faculty of Medicine, Jean Monnet University, Saint-Etienne, France.
Bourlet T; Laboratory of Infectious Agents and Hygiene GIMAP-EA3064, University Hospital & University Jean Monnet, Saint-Etienne, France.
Pillet S; Laboratory of Infectious Agents and Hygiene GIMAP-EA3064, University Hospital & University Jean Monnet, Saint-Etienne, France.
Verhoeven PO; Laboratory of Infectious Agents and Hygiene GIMAP-EA3064, University Hospital & University Jean Monnet, Saint-Etienne, France.
Forest F; Department of Pathology, University Hospital, Saint-Etienne, France.
Perrache C; Corneal Graft Biology, Engineering and Imaging Laboratory, Health Innovation Campus, Faculty of Medicine, Jean Monnet University, Saint-Etienne, France.
He Z; Corneal Graft Biology, Engineering and Imaging Laboratory, Health Innovation Campus, Faculty of Medicine, Jean Monnet University, Saint-Etienne, France.
Garcin T; Corneal Graft Biology, Engineering and Imaging Laboratory, Health Innovation Campus, Faculty of Medicine, Jean Monnet University, Saint-Etienne, France.; Department of Ophthalmology, University Hospital, Saint-Etienne, France.
Rousseau A; Department of Ophthalmology, Bicêtre Hospital, APHP, South Paris University, Le Kremlin-Bicêtre, France.; Center for Immunology of Viral Infections and Autoimmune Diseases, IMVA, UMR, INSERM, CEA, South Paris University, Fontenay-aux-Roses, France.
Labetoulle M; Department of Ophthalmology, Bicêtre Hospital, APHP, South Paris University, Le Kremlin-Bicêtre, France.; Center for Immunology of Viral Infections and Autoimmune Diseases, IMVA, UMR, INSERM, CEA, South Paris University, Fontenay-aux-Roses, France.
Gain P; Corneal Graft Biology, Engineering and Imaging Laboratory, Health Innovation Campus, Faculty of Medicine, Jean Monnet University, Saint-Etienne, France.; Department of Ophthalmology, University Hospital, Saint-Etienne, France.
Thuret G; Corneal Graft Biology, Engineering and Imaging Laboratory, Health Innovation Campus, Faculty of Medicine, Jean Monnet University, Saint-Etienne, France.; Department of Ophthalmology, University Hospital, Saint-Etienne, France.; Institut Universitaire de France, Paris, France.
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Źródło :
PloS one [PLoS One] 2020 Jul 22; Vol. 15 (7), pp. e0236183. Date of Electronic Publication: 2020 Jul 22 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Cornea/*pathology
Herpesvirus 1, Human/*pathogenicity
Keratitis, Herpetic/*pathology
Organ Culture Techniques/*instrumentation
Organ Preservation/*instrumentation
Aged ; Aged, 80 and over ; Cornea/diagnostic imaging ; Cornea/ultrastructure ; Cornea/virology ; Host Microbial Interactions ; Humans ; Keratitis, Herpetic/diagnosis ; Keratitis, Herpetic/drug therapy ; Keratitis, Herpetic/virology ; Microscopy, Electron, Transmission ; Middle Aged ; Organ Culture Techniques/methods ; Organ Preservation/methods ; Slit Lamp Microscopy
Czasopismo naukowe
Tytuł :
Characterization of feline herpesvirus-1 deletion mutants in tissue explant cultures.
Autorzy :
Lee Y; Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, 784 Wilson Road, East Lansing, MI 48824, USA. Electronic address: .
Maes R; Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, 784 Wilson Road, East Lansing, MI 48824, USA; Veterinary Diagnostic Laboratory, Michigan State University, 4125 Beaumont Road, Lansing, MI 48910, USA. Electronic address: .
Kiupel M; Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, 784 Wilson Road, East Lansing, MI 48824, USA; Veterinary Diagnostic Laboratory, Michigan State University, 4125 Beaumont Road, Lansing, MI 48910, USA. Electronic address: .
Nauwynck H; Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium. Electronic address: .
Soboll Hussey G; Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, 784 Wilson Road, East Lansing, MI 48824, USA. Electronic address: .
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Źródło :
Virus research [Virus Res] 2020 Jul 15; Vol. 284, pp. 197981. Date of Electronic Publication: 2020 Apr 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Deletion*
Mutation*
Organ Culture Techniques*
Varicellovirus/*genetics
Animals ; Cats ; Respiratory System/virology ; Tissue Culture Techniques ; Trachea/anatomy & histology ; Trachea/virology ; Viral Envelope Proteins/genetics ; Viral Proteins/genetics ; Virus Replication
SCR Organism :
Felid alphaherpesvirus 1
Czasopismo naukowe
Tytuł :
Ex vivo nail infection as an effective preclinical method for screening of new topical antifungals.
Autorzy :
Quatrin PM; Programa de Pós-Graduação em Microbiologia Agrícola e do Ambiente, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. Electronic address: .
Kaminski TFA; Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Berlitz SJ; Programa de Pós-Graduação em Nanotecnologia Farmacêutica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Guerreiro ICK; Programa de Pós-Graduação em Nanotecnologia Farmacêutica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Canto RFS; Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
Fuentefria AM; Programa de Pós-Graduação em Microbiologia Agrícola e do Ambiente, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
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Źródło :
Journal de mycologie medicale [J Mycol Med] 2020 Jun; Vol. 30 (2), pp. 100938. Date of Electronic Publication: 2020 Feb 09.
Typ publikacji :
Journal Article
MeSH Terms :
Organ Culture Techniques*
Swine*
Antifungal Agents/*administration & dosage
Drug Evaluation, Preclinical/*methods
Hoof and Claw/*pathology
Onychomycosis/*drug therapy
Administration, Topical ; Animals ; Antifungal Agents/pharmacology ; Cyanates/chemistry ; Hoof and Claw/drug effects ; Humans ; Lacquer ; Microbial Sensitivity Tests/methods ; Models, Biological ; Onychomycosis/pathology ; Permeability/drug effects ; Selenium Compounds/chemistry ; Terbinafine/administration & dosage ; Terbinafine/pharmacology ; Trichophyton/drug effects ; Trichophyton/growth & development
Czasopismo naukowe
Tytuł :
Lysophosphatidic acid improves corneal endothelial density in tissue culture by stimulating stromal secretion of interleukin-1β.
Autorzy :
Hsueh YJ; Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan.; Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, Taiwan.
Meir YJ; Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, Taiwan.; Department of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan.
Lai JY; Institute of Biochemical and Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan.; Department of Materials Engineering, Ming Chi University of Technology, New Taipei City, Taiwan.
Chen HC; Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan.; Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, Taiwan.; Department of Medicine, Chang Gung University, Taoyuan, Taiwan.
Ma DH; Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan.; Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, Taiwan.; Department of Chinese Medicine, Chang Gung University, Taoyuan, Taiwan.
Huang CC; Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, Taiwan.; Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu, Taiwan.
Lu TT; Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, Taiwan.; Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu, Taiwan.
Cheng CM; Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, Taiwan.; Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu, Taiwan.
Wu WC; Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan.; Department of Medicine, Chang Gung University, Taoyuan, Taiwan.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2020 Jun; Vol. 24 (12), pp. 6596-6608. Date of Electronic Publication: 2020 Apr 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Organ Culture Techniques*
Endothelium, Corneal/*drug effects
Interleukin-1beta/*metabolism
Lysophospholipids/*pharmacology
Animals ; Cell Count ; Cell Proliferation/drug effects ; Endothelial Cells/metabolism ; Humans ; Rabbits ; Stromal Cells/drug effects ; Stromal Cells/metabolism ; Wound Healing
Czasopismo naukowe
Tytuł :
Low Dose of Genistein Alleviates Mono-(2-Ethylhexyl) Phthalate-Induced Fetal Testis Disorder Based on Organ Culture Model.
Autorzy :
Zhang TD; Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Ma YB; Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Li HC; Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Chong T; Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Wang ZM; Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
Zhang LD; Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.
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Źródło :
Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2020 May 27; Vol. 2020, pp. 4569268. Date of Electronic Publication: 2020 May 27 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Organ Culture Techniques*
Diethylhexyl Phthalate/*analogs & derivatives
Fetus/*pathology
Genistein/*pharmacology
Testis/*embryology
Testis/*pathology
Animals ; Antioxidants/metabolism ; Basement Membrane/drug effects ; Basement Membrane/metabolism ; Basement Membrane/ultrastructure ; Biomarkers/metabolism ; Diethylhexyl Phthalate/toxicity ; Female ; Gene Expression Regulation, Developmental/drug effects ; Germ Cells/drug effects ; Germ Cells/metabolism ; Germ Cells/ultrastructure ; Leydig Cells/drug effects ; Leydig Cells/metabolism ; Leydig Cells/ultrastructure ; Male ; NF-E2-Related Factor 2/metabolism ; Oxidation-Reduction ; Rats, Sprague-Dawley ; Sertoli Cells/drug effects ; Sertoli Cells/metabolism ; Sertoli Cells/ultrastructure ; Testis/drug effects ; Testis/ultrastructure ; Testosterone/metabolism
Czasopismo naukowe
Tytuł :
Toxic Effects of Nonylphenol on Neonatal Testicular Development in Mouse Organ Culture.
Autorzy :
Park HJ; Department of Stem Cell and Regenerative Biology, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 05029, Korea.
Zhang M; Department of Stem Cell and Regenerative Biology, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 05029, Korea.
Lee WY; Department of Beef Science, Korea National College of Agricultures and Fisheries, Jeonju-si, Jeonbuk 54874, Korea.
Hong KH; Department of Stem Cell and Regenerative Biology, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 05029, Korea.
Do JT; Department of Stem Cell and Regenerative Biology, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 05029, Korea.
Park C; Department of Stem Cell and Regenerative Biology, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 05029, Korea.
Song H; Department of Stem Cell and Regenerative Biology, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 05029, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 May 15; Vol. 21 (10). Date of Electronic Publication: 2020 May 15.
Typ publikacji :
Journal Article
MeSH Terms :
Organ Culture Techniques*
Phenols/*toxicity
Testis/*growth & development
Animals ; Animals, Newborn ; Biomarkers/metabolism ; Female ; Fetus/drug effects ; Gene Expression Regulation, Developmental/drug effects ; Germ Cells/drug effects ; Germ Cells/metabolism ; Leydig Cells/drug effects ; Leydig Cells/metabolism ; Male ; Mice ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Sertoli Cells/drug effects ; Sertoli Cells/metabolism ; Testis/drug effects ; Testis/embryology
Czasopismo naukowe
Tytuł :
Effect of supersaturated oxygen emulsion treatment on chloropicrin-induced chemical injury in ex vivo rabbit cornea.
Autorzy :
Singh SK; Department of Pharmacology and Toxicology, Michigan State University, 1355 Bogue Street, East Lansing, MI, 48824, United States.
Goswami DG; University of Colorado, Anschutz Medical Campus, 12850 E. Montview Blvd., Aurora, CO, 80045, United States.
Wright HN; Department of Pharmacology and Toxicology, Michigan State University, 1355 Bogue Street, East Lansing, MI, 48824, United States.
Kant R; University of Colorado, Anschutz Medical Campus, 12850 E. Montview Blvd., Aurora, CO, 80045, United States.
Ali IA; Department of Pharmacology and Toxicology, Michigan State University, 1355 Bogue Street, East Lansing, MI, 48824, United States.
Braucher LN; Department of Pharmacology and Toxicology, Michigan State University, 1355 Bogue Street, East Lansing, MI, 48824, United States.
Klein JA; Department of Pharmacology and Toxicology, Michigan State University, 1355 Bogue Street, East Lansing, MI, 48824, United States.
Godziela MG; Department of Pharmacology and Toxicology, Michigan State University, 1355 Bogue Street, East Lansing, MI, 48824, United States.
Ammar DA; University of Colorado, Anschutz Medical Campus, 12850 E. Montview Blvd., Aurora, CO, 80045, United States.
Pate KM; Coruna Medical, LLC, Longmont, CO, United States.
Tewari-Singh N; Department of Pharmacology and Toxicology, Michigan State University, 1355 Bogue Street, East Lansing, MI, 48824, United States. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Oct 01; Vol. 349, pp. 124-133. Date of Electronic Publication: 2021 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Burns, Chemical/*drug therapy
Cornea/*drug effects
Eye Burns/*drug therapy
Hydrocarbons, Chlorinated/*toxicity
Oxygen/*pharmacology
Animals ; Apoptosis/drug effects ; Burns, Chemical/etiology ; Burns, Chemical/metabolism ; Burns, Chemical/pathology ; Cornea/metabolism ; Cornea/pathology ; Cytokines/metabolism ; DNA Damage ; Emulsions ; Eye Burns/chemically induced ; Eye Burns/metabolism ; Eye Burns/pathology ; Inflammation Mediators/metabolism ; Male ; Organ Culture Techniques ; Rabbits ; Wound Healing/drug effects
Czasopismo naukowe

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