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Tytuł:
Modification of Preservative Fluids with Antioxidants in Terms of Their Efficacy in Liver Protection before Transplantation.
Autorzy:
Ostróżka-Cieślik A; Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Kasztanowa 3, 41-200 Sosnowiec, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 03; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 03.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Liver Transplantation*/methods
Organ Preservation Solutions*/pharmacology
Reperfusion Injury*/prevention & control
End Stage Liver Disease*
Animals ; Humans ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Liver ; Organ Preservation/methods ; Perfusion ; Preservatives, Pharmaceutical
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Significantly Improved Cold Preservation of Rat Hind Limb Vascularized Composite Allografts Using the New PrC-210 Free Radical Scavenger.
Autorzy:
Fahl WE; Wisconsin Institute of Medical Research, University of Wisconsin-Madison, 111 Highland Ave., Madison, WI 53705, USA.
Nkana ZH; Division of Plastic Surgery, Department of Surgery, University of Wisconsin-Madison, 600 Highland Ave., Madison, WI 53705, USA.
Gitter MM; Wisconsin Institute of Medical Research, University of Wisconsin-Madison, 111 Highland Ave., Madison, WI 53705, USA.
Zeng W; Division of Plastic Surgery, Department of Surgery, University of Wisconsin-Madison, 600 Highland Ave., Madison, WI 53705, USA.
Dingle AM; Division of Plastic Surgery, Department of Surgery, University of Wisconsin-Madison, 600 Highland Ave., Madison, WI 53705, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 28; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Composite Tissue Allografts*/pathology
Reperfusion Injury*/pathology
Diamines*
Sulfhydryl Compounds*
Organ Preservation Solutions*
Rats ; Animals ; Free Radical Scavengers ; Caspase 3 ; Cytochromes c ; Quality of Life ; Rats, Inbred Lew ; Glutathione/pharmacology ; Allopurinol/pharmacology ; Insulin/pharmacology ; Ischemia ; Organ Preservation ; Cold Temperature ; Raffinose ; Adenosine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Thyroid hormone protects human lung epithelial cells from cold preservation and warm reperfusion-induced injury.
Autorzy:
Bojic D; Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Aujla T; Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.; Department of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Sugihara J; Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.
Wong A; Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Keshavjee S; Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Department of Surgery, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Liu M; Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada. .; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. .; Department of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. .; Department of Surgery, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Mar 01; Vol. 22 (1), pp. 221. Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Organ Preservation*/methods
Reperfusion Injury*
Humans ; Mice ; Animals ; Lung/metabolism ; Reperfusion ; Epithelial Cells/metabolism ; Thyroid Hormones/pharmacology ; Thyroid Hormones/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Machine perfusion of the liver and in vivo animal models: A systematic review of the preclinical research landscape.
Autorzy:
Liu W; Department of Surgery and Transplantation, Faculty of Medicine, University Hospital RWTH Aachen, Aachen, Germany.; Institute for Laboratory Animal Science and Experimental Surgery, Faculty of Medicine, RWTH, Aachen International University, Aachen, Germany.
Jiang D; Department of Surgery and Transplantation, Faculty of Medicine, University Hospital RWTH Aachen, Aachen, Germany.
Schulz M; Institute for Laboratory Animal Science and Experimental Surgery, Faculty of Medicine, RWTH, Aachen International University, Aachen, Germany.
Figueiredo C; Institute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, Hannover, Germany.
Dondossola D; General and Liver Transplant Surgery Unit, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, Milan, Italy.
Meister FA; Department of Surgery and Transplantation, Faculty of Medicine, University Hospital RWTH Aachen, Aachen, Germany.
Tihanyi DK; Doctoral School of Clinical Medicine, Semmelweis University, Budapest, Hungary.
Mehrabi A; Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.
Tolba RH; Institute for Laboratory Animal Science and Experimental Surgery, Faculty of Medicine, RWTH, Aachen International University, Aachen, Germany.
Czigany Z; Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.
Ernst L; Institute for Laboratory Animal Science and Experimental Surgery, Faculty of Medicine, RWTH, Aachen International University, Aachen, Germany.
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Źródło:
PloS one [PLoS One] 2024 Feb 08; Vol. 19 (2), pp. e0297942. Date of Electronic Publication: 2024 Feb 08 (Print Publication: 2024).
Typ publikacji:
Systematic Review; Journal Article
MeSH Terms:
Organ Preservation*/methods
Liver Transplantation*/methods
Swine ; Animals ; Dogs ; Rats ; Reproducibility of Results ; Liver ; Perfusion/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Role of IGL-2 Preservation Solution on Rat Livers during SCS and HOPE.
Autorzy:
Asong-Fontem N; Unité Chronothérapie, Cancers et Transplantation, Université Paris-Saclay, 94800 Villejuif, France.
Panisello-Rosello A; Experimental Hepatic Ischemia-Reperfusion Unit, Institut d'Investigacions Biomèdiques de Barcelona (IIBB), Spanish National Research Council (CSIC), 08036 Barcelona, Catalonia, Spain.
Sebagh M; Centre Hépato-Biliaire, APHP Hôpital Universitaire Paul Brousse, Université Paris-Saclay, 94800 Villejuif, France.
Gonin M; Unité Chronothérapie, Cancers et Transplantation, Université Paris-Saclay, 94800 Villejuif, France.
Rosello-Catafau J; Experimental Hepatic Ischemia-Reperfusion Unit, Institut d'Investigacions Biomèdiques de Barcelona (IIBB), Spanish National Research Council (CSIC), 08036 Barcelona, Catalonia, Spain.
Adam R; Unité Chronothérapie, Cancers et Transplantation, Université Paris-Saclay, 94800 Villejuif, France.; Centre Hépato-Biliaire, APHP Hôpital Universitaire Paul Brousse, Université Paris-Saclay, 94800 Villejuif, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 20; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 20.
Typ publikacji:
Journal Article
MeSH Terms:
Organ Preservation Solutions*/pharmacology
Organ Preservation Solutions*/metabolism
HMGB1 Protein*/metabolism
Fatty Liver*/metabolism
Rats ; Animals ; Organ Preservation ; Caspase 3/metabolism ; Rats, Zucker ; Liver/metabolism ; Transaminases/metabolism ; Perfusion
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Potential Route to Reduce Ischemia/Reperfusion Injury in Organ Preservation.
Autorzy:
Micó-Carnero M; Institut of Biomedical Research August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Zaouali MA; Laboratory of Human Genome and Multifactorial Diseases (LR12ES07), Faculty of Pharmacy, University of Monastir, Monastir 5000, Tunisia.
Rojano-Alfonso C; Institut of Biomedical Research August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Maroto-Serrat C; Institut of Biomedical Research August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Ben Abdennebi H; Laboratory of Human Genome and Multifactorial Diseases (LR12ES07), Faculty of Pharmacy, University of Monastir, Monastir 5000, Tunisia.
Peralta C; Institut of Biomedical Research August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
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Źródło:
Cells [Cells] 2022 Sep 05; Vol. 11 (17). Date of Electronic Publication: 2022 Sep 05.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Organ Preservation Solutions*/pharmacology
Reperfusion Injury*/prevention & control
Humans ; Ischemia ; Kidney ; Organ Preservation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Artificial oxygen carriers in organ preservation: Dose dependency in a rat model of ex-vivo normothermic kidney perfusion.
Autorzy:
Jägers J; Institute of Physiology, Essen University Hospital, University of Duisburg-Essen, Essen, Germany.; Department of Biomedicine, Aarhus University, Aarhus C, Denmark.
Kirsch M; Institute of Physiological Chemistry, Essen University Hospital, University of Duisburg-Essen, Essen, Germany.
Cantore M; Institute of Physiology, Essen University Hospital, University of Duisburg-Essen, Essen, Germany.
Karaman O; Institute of Physiology, Essen University Hospital, University of Duisburg-Essen, Essen, Germany.; Institute of Physiological Chemistry, Essen University Hospital, University of Duisburg-Essen, Essen, Germany.
Ferenz KB; Institute of Physiology, Essen University Hospital, University of Duisburg-Essen, Essen, Germany.; CeNIDE (Center for Nanointegration Duisburg-Essen) University of Duisburg-Essen, Duisburg, Germany.
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Źródło:
Artificial organs [Artif Organs] 2022 Sep; Vol. 46 (9), pp. 1783-1793. Date of Electronic Publication: 2022 Apr 23.
Typ publikacji:
Journal Article
MeSH Terms:
Kidney Transplantation*
Organ Preservation Solutions*
Albumins ; Animals ; Hypoxia ; Kidney/physiology ; Organ Preservation ; Oxygen ; Perfusion ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Melatonin in preservation solutions prevents ischemic injury in rat kidneys.
Autorzy:
Coskun A; Department of Medical Biochemistry, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.; Acibadem Labmed Clinical Laboratories, Istanbul, Turkey.
Yegen C; Department of General Surgery, Marmara University, School of Medicine, Istanbul, Turkey.
Arbak S; Department of Histology and Embryology, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.
Attaallah W; Department of General Surgery, Marmara University, School of Medicine, Istanbul, Turkey.
Gunal O; Department of General Surgery, Marmara University, School of Medicine, Istanbul, Turkey.
Elmas MA; Department of Histology and Embryology, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.
Ucal Y; Department of Medical Biochemistry, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.
Can O; Faculty of Engineering, Department of Medical Engineering, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Baş B; Department of Medical Biochemistry, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.
Yildirim Z; Department of Medical Biochemistry, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.
Seckin I; Department of Histology and Embryology, Istanbul University Cerrahpasa, Cerrahpasa School of Medicine, Istanbul, Turkey.
Demirci S; Department of Histology and Embryology, Biruni University, School of Medicine, Istanbul, Turkey.
Serteser M; Department of Medical Biochemistry, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.; Acibadem Labmed Clinical Laboratories, Istanbul, Turkey.
Ozpinar A; Department of Medical Biochemistry, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.
Belce A; Department of Medical Biochemistry, Biruni University, School of Medicine, Istanbul, Turkey.
Basdemir G; Department of Pathology, Memorial Hospital, Istanbul, Turkey.
Moldur DE; Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.
Derelioglu EI; Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.
Yozgatli TK; Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.
Erdemgil Y; Department of Medical Biochemistry, Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.
Unsal I; Acibadem Labmed Clinical Laboratories, Istanbul, Turkey.
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Źródło:
PloS one [PLoS One] 2022 Aug 31; Vol. 17 (8), pp. e0273921. Date of Electronic Publication: 2022 Aug 31 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Ischemia*/drug therapy
Ischemia*/metabolism
Kidney*/pathology
Melatonin*/pharmacology
Organ Preservation Solutions*/chemistry
Organ Preservation Solutions*/pharmacology
Adenosine ; Allopurinol/pharmacology ; Animals ; Glucosamine ; Glucose/pharmacology ; Glutathione/pharmacology ; Histidine/pharmacology ; Insulin/pharmacology ; Mannitol/pharmacology ; Organ Preservation/methods ; Potassium Chloride/pharmacology ; Raffinose/pharmacology ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical Evaluation of an HTK Solution for Liver Transplantation: A Phase 3 Randomized Pilot Clinical Trial Study.
Autorzy:
Malekhosseini SA; Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Ghasemi Y; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.; Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Rousta J; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Aghaei R; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Kianpour S; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Negahdaripour M; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.; Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Heidari R; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Shamsaeefar A; Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Gholami S; Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Nikeghbalian S; Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
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Źródło:
Archives of Iranian medicine [Arch Iran Med] 2022 Sep 01; Vol. 25 (9), pp. 617-623. Date of Electronic Publication: 2022 Sep 01.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase III; Journal Article
MeSH Terms:
Liver Transplantation*
Organ Preservation Solutions*
Male ; Adult ; Humans ; Pilot Projects ; Organ Preservation ; Liver ; Glucose ; Glutathione ; Insulin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Gluconate-Lactobionate-Dextran Perfusion Solutions Attenuate Ischemic Injury and Improve Function in a Murine Cardiac Transplant Model.
Autorzy:
Guo Y; Vascularized Composite Allotransplantation (VCA) Laboratory, Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Hand and Microsurgery, Xiangya Hospital, Central South University, Changsha 410017, China.
Messner F; Vascularized Composite Allotransplantation (VCA) Laboratory, Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Beck SE; Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Iglesias Lozano M; Vascularized Composite Allotransplantation (VCA) Laboratory, Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Schwelberger H; Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Zhang Y; Vascularized Composite Allotransplantation (VCA) Laboratory, Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Kammers K; Division of Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
Oh BC; Vascularized Composite Allotransplantation (VCA) Laboratory, Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Greene ED; Tissue Testing Technologies LLC, North Charleston, SC 29406, USA.
Brandacher G; Vascularized Composite Allotransplantation (VCA) Laboratory, Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Brockbank KGM; Tissue Testing Technologies LLC, North Charleston, SC 29406, USA.; Department of Bioengineering, Clemson University, Charleston, SC 29634, USA.
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Źródło:
Cells [Cells] 2022 May 16; Vol. 11 (10). Date of Electronic Publication: 2022 May 16.
Typ publikacji:
Journal Article
MeSH Terms:
Heart Transplantation*/methods
Organ Preservation Solutions*/pharmacology
Animals ; Dextrans ; Disaccharides ; Gluconates/pharmacology ; Glutathione ; Humans ; Ischemia ; Mice ; Organ Preservation/methods ; Perfusion/methods ; Tissue Donors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Assessment of machine perfusion conditions for the donation after circulatory death heart preservation.
Autorzy:
Cholyway R; Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Virginia Commonwealth University, Richmond, Virginia, USA.
Akande O; Pauley Heart Center, Virginia Commonwealth University Health System, Richmond, Virginia, USA.
Mauro AG; Pauley Heart Center, Virginia Commonwealth University Health System, Richmond, Virginia, USA.; Division of Cardiology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Mezzaroma E; Pauley Heart Center, Virginia Commonwealth University Health System, Richmond, Virginia, USA.; Department of Pharmacotherapy and Outcome Science, School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia, USA.
Wang R; Division of Cardiology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Kenning K; Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Virginia Commonwealth University, Richmond, Virginia, USA.
Toldo S; Pauley Heart Center, Virginia Commonwealth University Health System, Richmond, Virginia, USA.; Division of Cardiology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Quader M; Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Virginia Commonwealth University, Richmond, Virginia, USA.; Pauley Heart Center, Virginia Commonwealth University Health System, Richmond, Virginia, USA.; McGuire Veterans Administration Medical Center, Richmond, Virginia, USA.
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Źródło:
Artificial organs [Artif Organs] 2022 Jul; Vol. 46 (7), pp. 1346-1357. Date of Electronic Publication: 2022 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
Heart Transplantation*
Organ Preservation Solutions*/pharmacology
Animals ; Heart ; Humans ; Organ Preservation ; Perfusion ; Rats ; Troponin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Effect of Antioxidant Added to Preservation Solution on the Protection of Kidneys before Transplantation.
Autorzy:
Ostróżka-Cieślik A; Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Kasztanowa 3, 41-200 Sosnowiec, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Mar 15; Vol. 23 (6). Date of Electronic Publication: 2022 Mar 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Kidney Transplantation*/methods
Organ Preservation Solutions*/pharmacology
Reperfusion Injury*/prevention & control
Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Humans ; Kidney ; Organ Preservation/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Modeling energy depletion in rat livers using Nash equilibrium metabolic pathway analysis.
Autorzy:
Lucia A; Department of Chemical Engineering, University of Rhode Island, Kington, RI, 02881, USA. .
Ferrarese E; Department of Chemical Engineering, University of Rhode Island, Kington, RI, 02881, USA.
Uygun K; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, MA, 02114, USA.
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Źródło:
Scientific reports [Sci Rep] 2022 Mar 03; Vol. 12 (1), pp. 3496. Date of Electronic Publication: 2022 Mar 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Liver Transplantation*
Organ Preservation Solutions*/metabolism
Adenosine ; Allopurinol ; Animals ; Cold Temperature ; Glutathione/metabolism ; Humans ; Insulin/metabolism ; Liver/metabolism ; Metabolic Networks and Pathways ; Organ Preservation/methods ; Raffinose/metabolism ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mitoquinone Alleviates Donation after Cardiac Death Kidney Injury during Hypothermic Machine Perfusion in Rat Model.
Autorzy:
Radajewska A; Division of Clinical Chemistry and Laboratory Hematology, Department of Medical Laboratory Diagnostics, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.
Szyller J; Division of Clinical Chemistry and Laboratory Hematology, Department of Medical Laboratory Diagnostics, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.
Krzywonos-Zawadzka A; Division of Clinical Chemistry and Laboratory Hematology, Department of Medical Laboratory Diagnostics, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.
Olejnik A; Division of Clinical Chemistry and Laboratory Hematology, Department of Medical Laboratory Diagnostics, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.
Sawicki G; Division of Clinical Chemistry and Laboratory Hematology, Department of Medical Laboratory Diagnostics, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.; Department of Anatomy, Physiology and Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Bil-Lula I; Division of Clinical Chemistry and Laboratory Hematology, Department of Medical Laboratory Diagnostics, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 30; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 30.
Typ publikacji:
Journal Article
MeSH Terms:
Organ Preservation*
Reperfusion Injury*/metabolism
Humans ; Rats ; Animals ; Reactive Oxygen Species ; Proto-Oncogene Proteins c-akt ; Kidney/metabolism ; Perfusion ; Antioxidants ; Death
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Does pediatric heart transplant survival differ with various cardiac preservation solutions?
Autorzy:
Shaw TB; Department of Surgery, University of Mississippi Medical Center, Jackson, MS, USA.
Lirette S; Department of Data Science, University of Mississippi Medical Center, Jackson, MS, USA.
Carter KT; Department of Surgery, University of Mississippi Medical Center, Jackson, MS, USA.
Kutcher ME; Department of Surgery, Division of Trauma and Critical Care, University of Mississippi Medical Center, Jackson, MS, USA.
Baran DA; Sentara Heart Hospital, Norfolk, VA, USA.
Copeland JG; Department of Surgery, University of Arizona, Tucson, AZ, USA.
Copeland H; Lutheran Medical Hospital, Fort Wayne, IN, USA.; Indiana University School of Medicine, Fort Wayne, IN, USA.
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Źródło:
Clinical transplantation [Clin Transplant] 2020 Dec; Vol. 34 (12), pp. e14122. Date of Electronic Publication: 2020 Nov 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Heart Transplantation*
Organ Preservation Solutions*
Child ; Heart ; Humans ; Insulin ; Organ Preservation ; Retrospective Studies ; Tissue Donors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The role of flavin mononucleotide (FMN) as a potentially clinically relevant biomarker to predict the quality of kidney grafts during hypothermic (oxygenated) machine perfusion.
Autorzy:
van de Leemkolk FEM; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.; LUMC Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.
Lo Faro ML; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, United Kingdom.
Shaheed S; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, United Kingdom.
Mulvey JF; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.
Huurman VAL; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.; LUMC Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.
Alwayn IPJ; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.; LUMC Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.
Putter H; LUMC Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.
Jochmans I; Department of Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium.; Transplantation Research Group, Lab of Abdominal Transplantation, Department of Microbiology, Immunology, and Transplantation, KU Leuven, Belgium.
Lindeman JHN; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.; LUMC Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.
Ploeg RJ; LUMC Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, United Kingdom.
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Corporate Authors:
COMPARE Trial Collaboration and the Consortium for Organ Preservation in Europe (COPE)
Źródło:
PloS one [PLoS One] 2023 Jun 23; Vol. 18 (6), pp. e0287713. Date of Electronic Publication: 2023 Jun 23 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Flavin Mononucleotide*
Organ Preservation*/methods
Chromatography, Liquid ; Tandem Mass Spectrometry ; Renal Dialysis ; Kidney ; Perfusion/methods ; Biomarkers
Czasopismo naukowe
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Tytuł:
Preservation solutions to improve graft patency: The devil is in the detail.
Autorzy:
Caliskan E; Department of Cardiovascular Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.; Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, German Heart Institute Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
Pachuk CJ; Somahlution Inc, Jupiter, USA.
Perrault LP; Department of Cardiac Surgery, Montreal Heart Institute, Université de Montréal, Montreal, Canada.
Emmert MY; Department of Cardiovascular Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany. .; Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, German Heart Institute Berlin, Augustenburger Platz 1, 13353, Berlin, Germany. .
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Źródło:
Journal of cardiothoracic surgery [J Cardiothorac Surg] 2020 Aug 27; Vol. 15 (1), pp. 228. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji:
Letter; Comment
MeSH Terms:
Organ Preservation Solutions*
Animals ; Organ Preservation ; Rats
Opinia redakcyjna
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Tytuł:
HTK vs. HTK-N for Coronary Endothelial Protection during Hypothermic, Oxygenated Perfusion of Hearts Donated after Circulatory Death.
Autorzy:
Saemann L; Department of Cardiac Surgery, University Hospital Halle (Saale), University of Halle, 06120 Halle (Saale), Germany.; Department of Cardiac Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Wächter K; Department of Cardiac Surgery, University Hospital Halle (Saale), University of Halle, 06120 Halle (Saale), Germany.
Gharpure N; Department of Cardiac Surgery, University Hospital Halle (Saale), University of Halle, 06120 Halle (Saale), Germany.
Pohl S; Department of Cardiac Surgery, University Hospital Halle (Saale), University of Halle, 06120 Halle (Saale), Germany.
Hoorn F; Department of Cardiac Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Korkmaz-Icöz S; Department of Cardiac Surgery, University Hospital Halle (Saale), University of Halle, 06120 Halle (Saale), Germany.; Department of Cardiac Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Karck M; Department of Cardiac Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Veres G; Department of Cardiac Surgery, University Hospital Halle (Saale), University of Halle, 06120 Halle (Saale), Germany.; Department of Cardiac Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Simm A; Department of Cardiac Surgery, University Hospital Halle (Saale), University of Halle, 06120 Halle (Saale), Germany.
Szabó G; Department of Cardiac Surgery, University Hospital Halle (Saale), University of Halle, 06120 Halle (Saale), Germany.; Department of Cardiac Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 13; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Heart Transplantation*/methods
Swine ; Animals ; Humans ; Tissue Donors ; Heart ; Perfusion ; Coronary Vessels/physiology ; Organ Preservation/methods
Czasopismo naukowe
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Tytuł:
A prospective, randomized, single-blind, multicentre, phase III study on organ preservation with Custodiol-N solution compared with Custodiol® solution in organ transplantation (kidney, liver and pancreas).
Autorzy:
Kniepeiss D; General, Visceral and Transplant Surgery, Department of Surgery, Medical University of Graz, Auenbruggerplatz 29, 8036, Graz, Austria.; Transplant Center Graz (TCG), Medical University of Graz, Auenbruggerplatz 29, 8036, Graz, Austria.
Houben P; Department of General, Visceral and Transplant Surgery, University Hospital of Heidelberg, Heidelberg, Germany.
Stiegler P; General, Visceral and Transplant Surgery, Department of Surgery, Medical University of Graz, Auenbruggerplatz 29, 8036, Graz, Austria.; Transplant Center Graz (TCG), Medical University of Graz, Auenbruggerplatz 29, 8036, Graz, Austria.
Berghold A; Institute for Medical Informatics, Statistics and Documentation, Medical University Graz, Graz, Austria.
Riedl R; Institute for Medical Informatics, Statistics and Documentation, Medical University Graz, Graz, Austria.
Kahn J; General, Visceral and Transplant Surgery, Department of Surgery, Medical University of Graz, Auenbruggerplatz 29, 8036, Graz, Austria.; Transplant Center Graz (TCG), Medical University of Graz, Auenbruggerplatz 29, 8036, Graz, Austria.
Schemmer P; General, Visceral and Transplant Surgery, Department of Surgery, Medical University of Graz, Auenbruggerplatz 29, 8036, Graz, Austria. .; Transplant Center Graz (TCG), Medical University of Graz, Auenbruggerplatz 29, 8036, Graz, Austria. .
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Źródło:
Trials [Trials] 2020 Jan 10; Vol. 21 (1), pp. 62. Date of Electronic Publication: 2020 Jan 10.
Typ publikacji:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Kidney Transplantation*/adverse effects
Liver Transplantation*/adverse effects
Organ Preservation*/adverse effects
Pancreas Transplantation*/adverse effects
Tissue and Organ Harvesting*/adverse effects
Graft Survival/*drug effects
Organ Preservation Solutions/*therapeutic use
Austria ; Clinical Trials, Phase III as Topic ; Glucose/adverse effects ; Glucose/therapeutic use ; Humans ; Mannitol/adverse effects ; Mannitol/therapeutic use ; Multicenter Studies as Topic ; Organ Preservation Solutions/adverse effects ; Potassium Chloride/adverse effects ; Potassium Chloride/therapeutic use ; Procaine/adverse effects ; Procaine/therapeutic use ; Prospective Studies ; Randomized Controlled Trials as Topic ; Single-Blind Method ; Time Factors ; Treatment Outcome
Czasopismo naukowe
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Tytuł:
The effect of blood cells retained in rat livers during static cold storage on viability outcomes during normothermic machine perfusion.
Autorzy:
Haque O; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 51 Blossom St, Boston, MA, 02114, USA.; Shriners Hospitals for Children, Boston, MA, USA.; Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Department of Surgery, Division of Transplantation, Center for Transplantation Science, Massachusetts General Hospital, 32 Fruit Street, Boston, MA, 02114, USA.; Harvard Medical School, Boston, MA, USA.
Pendexter CA; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 51 Blossom St, Boston, MA, 02114, USA.; Shriners Hospitals for Children, Boston, MA, USA.
Wilks BT; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 51 Blossom St, Boston, MA, 02114, USA.; Shriners Hospitals for Children, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Hafiz EOA; Department of Electron Microscopy Research, Theodor Bilharz Research Institute, Giza, Egypt.
Markmann JF; Department of Surgery, Division of Transplantation, Center for Transplantation Science, Massachusetts General Hospital, 32 Fruit Street, Boston, MA, 02114, USA.; Harvard Medical School, Boston, MA, USA.
Uygun K; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 51 Blossom St, Boston, MA, 02114, USA.; Shriners Hospitals for Children, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Yeh H; Department of Surgery, Division of Transplantation, Center for Transplantation Science, Massachusetts General Hospital, 32 Fruit Street, Boston, MA, 02114, USA. .; Harvard Medical School, Boston, MA, USA. .
Tessier SN; Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 51 Blossom St, Boston, MA, 02114, USA. .; Shriners Hospitals for Children, Boston, MA, USA. .; Harvard Medical School, Boston, MA, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Nov 30; Vol. 11 (1), pp. 23128. Date of Electronic Publication: 2021 Nov 30.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Blood Cells/*drug effects
Blood Cells/*pathology
Liver/*pathology
Organ Preservation/*methods
Perfusion/*methods
Adenosine ; Allografts ; Allopurinol ; Animals ; Cold Ischemia/adverse effects ; Cold Temperature ; Gastroenterology ; Glutathione ; Insulin ; Liver Transplantation ; Organ Preservation Solutions/pharmacology ; Raffinose ; Rats ; Rats, Sprague-Dawley ; Ringer's Lactate ; Tissue Donors
Czasopismo naukowe
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Wyświetlanie 1-20 z 3815

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