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Tytuł :
Conjugates of human serum butyrylcholinesterase and nerve agents are behaviorally safe in rhesus macaques.
Autorzy :
Saxena A; Division of Biochemistry, Walter Reed Army Institute of Research, Silver Spring, MD, 20910, USA. Electronic address: .
Myers TM; Pharmaceutical Sciences Department, Unites States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD, 21010, USA.
Sipos ML; US Army War College, Carlisle, PA, 17013, USA.
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Aug 01; Vol. 344, pp. 109499. Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Butyrylcholinesterase/*toxicity
Nerve Agents/*toxicity
Organothiophosphorus Compounds/*toxicity
Soman/*toxicity
Animals ; Butyrylcholinesterase/chemistry ; Butyrylcholinesterase/pharmacokinetics ; Diazepam/pharmacology ; Female ; Humans ; Macaca mulatta ; Male ; Memory/drug effects ; Nerve Agents/chemistry ; Nerve Agents/pharmacokinetics ; Organothiophosphorus Compounds/chemistry ; Organothiophosphorus Compounds/pharmacokinetics ; Soman/chemistry ; Soman/pharmacokinetics
Czasopismo naukowe
Tytuł :
Towards catch-up therapy: evaluation of nucleophilic active pharmaceutical ingredients for the treatment of percutaneous VX poisoning, in-vial and in-vitro studies.
Autorzy :
Nahum V; Department of Organic Chemistry, IIBR - Israel Institute for Biological Research, P.O. Box 19, Ness Ziona 7410001, Israel.
Nili U; Department of Pharmacology, IIBR - Israel Institute for Biological Research, P.O. Box 19, Ness Ziona 7410001, Israel.
Bloch-Shilderman E; Department of Pharmacology, IIBR - Israel Institute for Biological Research, P.O. Box 19, Ness Ziona 7410001, Israel.
Smolkin B; Department of Organic Chemistry, IIBR - Israel Institute for Biological Research, P.O. Box 19, Ness Ziona 7410001, Israel. Electronic address: .
Ashkenazi N; Department of Organic Chemistry, IIBR - Israel Institute for Biological Research, P.O. Box 19, Ness Ziona 7410001, Israel. Electronic address: .
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Źródło :
International journal of pharmaceutics [Int J Pharm] 2021 Jun 15; Vol. 603, pp. 120689. Date of Electronic Publication: 2021 May 07.
Typ publikacji :
Journal Article
MeSH Terms :
Chemical Warfare Agents*
Organothiophosphorus Compounds*
Pharmaceutical Preparations*
Animals ; Decontamination ; Swine
Czasopismo naukowe
Tytuł :
GYY4137 alleviates sepsis-induced acute lung injury in mice by inhibiting the PDGFRβ/Akt/NF-κB/NLRP3 pathway.
Autorzy :
Li J; Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Department of Critical Care Medicine, The First Affiliated Hospital, College of Medicine, Shihezi University, Shihezi 832000, China.
Ma J; Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Li M; Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Tao J; Department of Orthopedics, The Third Affiliated Hospital, College of Medicine, Shihezi University, Shihezi 832000, China.
Chen J; Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Yao C; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address: .
Yao S; Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Apr 15; Vol. 271, pp. 119192. Date of Electronic Publication: 2021 Feb 10.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Lung Injury/*drug therapy
Morpholines/*therapeutic use
NF-kappa B/*antagonists & inhibitors
NLR Family, Pyrin Domain-Containing 3 Protein/*antagonists & inhibitors
Organothiophosphorus Compounds/*therapeutic use
Proto-Oncogene Proteins c-akt/*antagonists & inhibitors
Receptor, Platelet-Derived Growth Factor beta/*antagonists & inhibitors
Sepsis/*drug therapy
Acute Lung Injury/etiology ; Acute Lung Injury/metabolism ; Animals ; Male ; Mice ; Mice, Inbred C57BL ; Morpholines/pharmacology ; NF-kappa B/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Organothiophosphorus Compounds/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; RAW 264.7 Cells ; Receptor, Platelet-Derived Growth Factor beta/metabolism ; Sepsis/complications ; Sepsis/metabolism ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
In vitro human skin decontamination efficacy of MOF-808 in decontamination lotion following exposure to the nerve agent VX.
Autorzy :
Larsson A; Swedish Defence Research Agency, CBRN Defence and Security, Umeå, Sweden.
Qvarnström J; Swedish Defence Research Agency, CBRN Defence and Security, Umeå, Sweden.
Lindberg S; Swedish Defence Research Agency, CBRN Defence and Security, Umeå, Sweden.
Wigenstam E; Swedish Defence Research Agency, CBRN Defence and Security, Umeå, Sweden.
Öberg L; Swedish Defence Research Agency, CBRN Defence and Security, Umeå, Sweden.
Afshin Sander R; Swedish Defence Research Agency, CBRN Defence and Security, Umeå, Sweden.
Johansson S; Swedish Defence Research Agency, CBRN Defence and Security, Umeå, Sweden.
Bucht A; Swedish Defence Research Agency, CBRN Defence and Security, Umeå, Sweden.
Thors L; Swedish Defence Research Agency, CBRN Defence and Security, Umeå, Sweden. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Mar 15; Vol. 339, pp. 32-38. Date of Electronic Publication: 2020 Dec 25.
Typ publikacji :
Journal Article
MeSH Terms :
Chemical Warfare Agents/*toxicity
Decontamination/*methods
Metal-Organic Frameworks/*therapeutic use
Nerve Agents/*toxicity
Organothiophosphorus Compounds/*toxicity
Skin/*drug effects
Zirconium/*therapeutic use
Cells, Cultured/drug effects ; Chemical Warfare Agents/metabolism ; Humans ; Nerve Agents/metabolism ; Organothiophosphorus Compounds/metabolism ; Skin Cream
Czasopismo naukowe
Tytuł :
Mitochondrial hydrogen sulfide supplementation improves health in the C. elegans Duchenne muscular dystrophy model.
Autorzy :
Ellwood RA; Medical Research Council (MRC) Versus Arthritis Centre for Musculoskeletal Ageing Research, Royal Derby Hospital, University of Nottingham, Derby DE22 3DT, United Kingdom.; Musculoskeletal Conditions, National Institute for Health Research Nottingham Biomedical Research Centre, Derby DE22 3DT, United Kingdom.
Hewitt JE; Department of Chemical Engineering, Texas Tech University, Lubbock, TX 79409.; Molecular Genetics of Ageing, Max Planck Institute for Biology of Ageing, 50931 Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany.
Torregrossa R; University of Exeter Medical School, University of Exeter, EX1 2LU Exeter, United Kingdom.
Philp AM; Mitochondrial Metabolism and Ageing, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.; St. Vincent's Clinical School, University of New South Wales (UNSW) Medicine, University of New South Wales Sydney, Sydney, NSW 2052, Australia.
Hardee JP; Centre for Muscle Research, Department of Anatomy and Physiology, The University of Melbourne, Melbourne, VIC 3010, Australia.
Hughes S; HAN BioCentre, HAN University of Applied Sciences, Nijmegen 6525EM, The Netherlands.
van de Klashorst D; HAN BioCentre, HAN University of Applied Sciences, Nijmegen 6525EM, The Netherlands.
Gharahdaghi N; Medical Research Council (MRC) Versus Arthritis Centre for Musculoskeletal Ageing Research, Royal Derby Hospital, University of Nottingham, Derby DE22 3DT, United Kingdom.; Musculoskeletal Conditions, National Institute for Health Research Nottingham Biomedical Research Centre, Derby DE22 3DT, United Kingdom.
Anupom T; Department of Electrical and Computer Engineering, Texas Tech University, Lubbock, TX 79409.
Slade L; University of Exeter Medical School, University of Exeter, EX1 2LU Exeter, United Kingdom.; Sport and Health Sciences, University of Exeter, EX1 2LU Exeter, United Kingdom.
Deane CS; Sport and Health Sciences, University of Exeter, EX1 2LU Exeter, United Kingdom.; Living System Institute, University of Exeter, EX4 4QD Exeter, United Kingdom.
Cooke M; Medical Research Council (MRC) Versus Arthritis Centre for Musculoskeletal Ageing Research, Royal Derby Hospital, University of Nottingham, Derby DE22 3DT, United Kingdom.; Musculoskeletal Conditions, National Institute for Health Research Nottingham Biomedical Research Centre, Derby DE22 3DT, United Kingdom.; Sport and Health Sciences, University of Exeter, EX1 2LU Exeter, United Kingdom.
Etheridge T; Sport and Health Sciences, University of Exeter, EX1 2LU Exeter, United Kingdom.
Piasecki M; Medical Research Council (MRC) Versus Arthritis Centre for Musculoskeletal Ageing Research, Royal Derby Hospital, University of Nottingham, Derby DE22 3DT, United Kingdom.; Musculoskeletal Conditions, National Institute for Health Research Nottingham Biomedical Research Centre, Derby DE22 3DT, United Kingdom.
Antebi A; Molecular Genetics of Ageing, Max Planck Institute for Biology of Ageing, 50931 Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany.
Lynch GS; Centre for Muscle Research, Department of Anatomy and Physiology, The University of Melbourne, Melbourne, VIC 3010, Australia.
Philp A; Mitochondrial Metabolism and Ageing, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.; St. Vincent's Clinical School, University of New South Wales (UNSW) Medicine, University of New South Wales Sydney, Sydney, NSW 2052, Australia.
Vanapalli SA; Department of Chemical Engineering, Texas Tech University, Lubbock, TX 79409.
Whiteman M; University of Exeter Medical School, University of Exeter, EX1 2LU Exeter, United Kingdom; .
Szewczyk NJ; Medical Research Council (MRC) Versus Arthritis Centre for Musculoskeletal Ageing Research, Royal Derby Hospital, University of Nottingham, Derby DE22 3DT, United Kingdom; .; Musculoskeletal Conditions, National Institute for Health Research Nottingham Biomedical Research Centre, Derby DE22 3DT, United Kingdom.; Ohio Musculoskeletal and Neurologic Institute, Ohio University, Athens, OH 45701.; Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Mar 02; Vol. 118 (9).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Caenorhabditis elegans Proteins/*genetics
Dystrophin/*genetics
Hydrogen Sulfide/*pharmacology
Mitochondria, Muscle/*drug effects
Morpholines/*pharmacology
Muscle, Skeletal/*drug effects
Muscular Dystrophy, Animal/*drug therapy
Organophosphorus Compounds/*pharmacology
Organothiophosphorus Compounds/*pharmacology
Thiones/*pharmacology
Animals ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans Proteins/metabolism ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Dystrophin/deficiency ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism ; Gene Expression Regulation ; Humans ; Hydrogen Sulfide/metabolism ; Locomotion/drug effects ; Locomotion/genetics ; Male ; Mice ; Mice, Inbred mdx ; Mitochondria, Muscle/metabolism ; Mitochondria, Muscle/pathology ; Mitogen-Activated Protein Kinases/genetics ; Mitogen-Activated Protein Kinases/metabolism ; Morpholines/metabolism ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/pathology ; Muscular Dystrophy, Animal/genetics ; Muscular Dystrophy, Animal/metabolism ; Muscular Dystrophy, Animal/pathology ; Muscular Dystrophy, Duchenne/drug therapy ; Muscular Dystrophy, Duchenne/genetics ; Muscular Dystrophy, Duchenne/metabolism ; Muscular Dystrophy, Duchenne/pathology ; Organophosphorus Compounds/metabolism ; Organothiophosphorus Compounds/metabolism ; Prednisone/pharmacology ; Sirtuins/genetics ; Sirtuins/metabolism ; Thiones/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Utrophin/deficiency ; Utrophin/genetics
Czasopismo naukowe
Tytuł :
Quinalphos Tolerant Endophytic Bacillus sp. Fcl1 and its Toxicity-Alleviating Effect in Vigna unguiculata.
Autorzy :
Juby S; School of Biosciences, Mahatma Gandhi University, P.D Hills (P.O), Kottayam, Kerala, 686 560, India.
Choyikutty D; School of Biosciences, Mahatma Gandhi University, P.D Hills (P.O), Kottayam, Kerala, 686 560, India.
Nayana AR; School of Biosciences, Mahatma Gandhi University, P.D Hills (P.O), Kottayam, Kerala, 686 560, India.
Jayachandran K; School of Biosciences, Mahatma Gandhi University, P.D Hills (P.O), Kottayam, Kerala, 686 560, India.
Radhakrishnan EK; School of Biosciences, Mahatma Gandhi University, P.D Hills (P.O), Kottayam, Kerala, 686 560, India. .
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Źródło :
Current microbiology [Curr Microbiol] 2021 Mar; Vol. 78 (3), pp. 904-910. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article
MeSH Terms :
Bacillus*
Organothiophosphorus Compounds*
Vigna*
Soil
Czasopismo naukowe
Tytuł :
Identification of 2-(diethylamino)ethylthiol dipeptide (Cys-Pro) adduct as biomarker of nerve agents VR and CVX in human plasma using liquid chromatography-high-resolution tandem mass spectrometry.
Autorzy :
Baygildiev ТМ; Department of Chemistry, Lomonosov Moscow State University, Moscow, Russia, 119991.
Vokuev MF; Department of Chemistry, Lomonosov Moscow State University, Moscow, Russia, 119991. .
Braun AV; Department of Chemistry, Lomonosov Moscow State University, Moscow, Russia, 119991.; Laboratory for the Chemical and Analytical Control of the Military Research Centre, Moscow, Russia, 105005.
Yashkir VA; Laboratory for the Chemical and Analytical Control of the Military Research Centre, Moscow, Russia, 105005.
Rуbalchenko IV; Department of Chemistry, Lomonosov Moscow State University, Moscow, Russia, 119991.; Laboratory for the Chemical and Analytical Control of the Military Research Centre, Moscow, Russia, 105005.
Rodin IA; Department of Chemistry, Lomonosov Moscow State University, Moscow, Russia, 119991.; Department of Epidemiology and Evidence Based Medicine, I.M. Sechenov First Moscow State Medical University, Moscow, Russia, 119435.
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Źródło :
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2021 Mar; Vol. 413 (7), pp. 1905-1916. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers/*analysis
Nerve Agents/*analysis
Organothiophosphorus Compounds/*analysis
Albumins/analysis ; Biomarkers/blood ; Chromatography, Liquid/methods ; Drug Design ; Fermentation ; Humans ; Hydrolysis ; Ions ; Limit of Detection ; Organothiophosphorus Compounds/blood ; Plasma/metabolism ; Reproducibility of Results ; Risk ; Tandem Mass Spectrometry/methods
Czasopismo naukowe
Tytuł :
The effect of ethion on erythrocyte deformability.
Autorzy :
Özkul T; Erciyes University Health Vocational Collage, 38039 Kayseri, Turkey. Electronic address: .
Günal SY; Erciyes University Health Vocational Collage, 38039 Kayseri, Turkey. Electronic address: .
Aydoğan S; Physiology Department, Medical Faculty, Erciyes University, Turkey.
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Źródło :
Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2021 Feb; Vol. 172, pp. 104753. Date of Electronic Publication: 2020 Dec 01.
Typ publikacji :
Journal Article
MeSH Terms :
Erythrocyte Deformability*
Organothiophosphorus Compounds*
Animals ; Erythrocytes ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Computational and Experimental Approaches to Decipher the Binding Mechanism of General Odorant-Binding Protein 2 from Athetis lepigone to Chlorpyrifos and Phoxim.
Autorzy :
Zhang YN; Anhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, College of Life Sciences, Huaibei Normal University, Huaibei 235000, China.
Zhang XC; Anhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, College of Life Sciences, Huaibei Normal University, Huaibei 235000, China.
Zhu R; Anhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, College of Life Sciences, Huaibei Normal University, Huaibei 235000, China.
Yao WC; Anhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, College of Life Sciences, Huaibei Normal University, Huaibei 235000, China.
Xu JW; Anhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, College of Life Sciences, Huaibei Normal University, Huaibei 235000, China.
Wang M; Anhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, College of Life Sciences, Huaibei Normal University, Huaibei 235000, China.
Ren JY; Zhuhai College of Jilin University, Zhuhai 519041, China.; Institute of Biomedicine, Jinan University, Guangzhou 510632, P. R. China.
Xu CZ; Anhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, College of Life Sciences, Huaibei Normal University, Huaibei 235000, China.
Huang ZR; Anhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, College of Life Sciences, Huaibei Normal University, Huaibei 235000, China.
Zhang XW; Anhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, College of Life Sciences, Huaibei Normal University, Huaibei 235000, China.
Yu W; Zhuhai College of Jilin University, Zhuhai 519041, China.; Institute of Biomedicine, Jinan University, Guangzhou 510632, P. R. China.
Liao HX; Institute of Biomedicine, Jinan University, Guangzhou 510632, P. R. China.
Yuan XH; Institute of Biomedicine, Jinan University, Guangzhou 510632, P. R. China.; Zhuhai Trinomab Biotechnology Co., Ltd., Zhuhai 519040, China.
Wu XM; Anhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, College of Life Sciences, Huaibei Normal University, Huaibei 235000, China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2021 Jan 13; Vol. 69 (1), pp. 88-100. Date of Electronic Publication: 2020 Dec 27.
Typ publikacji :
Journal Article
MeSH Terms :
Chlorpyrifos/*chemistry
Insect Proteins/*chemistry
Moths/*metabolism
Organothiophosphorus Compounds/*chemistry
Receptors, Odorant/*chemistry
Receptors, Odorant/*metabolism
Animals ; Chlorpyrifos/metabolism ; Insect Proteins/metabolism ; Molecular Dynamics Simulation ; Moths/chemistry ; Organothiophosphorus Compounds/metabolism ; Protein Binding
Czasopismo naukowe
Tytuł :
Chronic Treatment With Hydrogen Sulfide Donor GYY4137 Mitigates Microglial and Astrocyte Activation in the Spinal Cord of Streptozotocin-Induced Diabetic Rats.
Autorzy :
Shayea AMF; Departments of Anatomy, Faculty of Medicine Health Science Center.; Occupational Therapy Faculty of Allied Health.
Mousa AMA; Departments of Anatomy, Faculty of Medicine Health Science Center.
Renno WM; Departments of Anatomy, Faculty of Medicine Health Science Center.
Nadar MS; Occupational Therapy Faculty of Allied Health.
Qabazard B; Pharmacology and Therapeutics, Faculty of Pharmacy.
Yousif MHM; Pharmacology & Toxicology Department, Faculty of Medicine (MHMY), Kuwait University, Kuwait.
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Źródło :
Journal of neuropathology and experimental neurology [J Neuropathol Exp Neurol] 2020 Dec 04; Vol. 79 (12), pp. 1320-1343.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*drug effects
Diabetes Mellitus, Experimental/*metabolism
Diabetic Neuropathies/*drug therapy
Microglia/*drug effects
Morpholines/*pharmacology
Neuroprotective Agents/*pharmacology
Organothiophosphorus Compounds/*pharmacology
Spinal Cord/*drug effects
Animals ; Astrocytes/metabolism ; Cytokines/metabolism ; Diabetic Neuropathies/metabolism ; Hyperalgesia/drug therapy ; Hyperalgesia/metabolism ; Inflammation Mediators/metabolism ; Male ; Microglia/metabolism ; Morpholines/therapeutic use ; Neuroprotective Agents/therapeutic use ; Organothiophosphorus Compounds/therapeutic use ; Rats ; Rats, Sprague-Dawley ; Spinal Cord/metabolism ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Do background levels of the pesticide pirimiphosmethyl in plant-based aquafeeds affect food safety of farmed Atlantic salmon?
Autorzy :
Berntssen MHG; Department of Feed Safety, Institute of Marine Research (IMR) , Bergen, Norway.
Hoogenveen R; RIVM, National Institute for Public Health and the Environment , Bilthoven, The Netherlands.
Rosenlund G; Skretting ARC , Stavanger, Norway.
Garlito B; Research Institute for Pesticides and Water (IUPA), University JaumeI , Castellón, Spain.
Zeilmaker MJ; RIVM, National Institute for Public Health and the Environment , Bilthoven, The Netherlands.
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Źródło :
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment [Food Addit Contam Part A Chem Anal Control Expo Risk Assess] 2020 Dec; Vol. 37 (12), pp. 2109-2122. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Journal Article
MeSH Terms :
Animal Feed/*analysis
Food Contamination/*analysis
Organothiophosphorus Compounds/*analysis
Pesticides/*analysis
Seafood/*analysis
Animals ; Fisheries ; Food Analysis ; Food Safety ; Organothiophosphorus Compounds/metabolism ; Pesticides/metabolism ; Plants/chemistry ; Plants/metabolism ; Salmo salar
Czasopismo naukowe
Tytuł :
Estimating the optimal interval between rounds of indoor residual spraying of insecticide using malaria incidence data from cohort studies.
Autorzy :
Mugenyi L; College of Health Sciences, Makerere University, Kampala, Uganda.; The Aids Support Organization, Kampala, Uganda.
Nankabirwa JI; College of Health Sciences, Makerere University, Kampala, Uganda.; Infectious Diseases Research Collaboration, Kampala, Uganda.
Arinaitwe E; Infectious Diseases Research Collaboration, Kampala, Uganda.
Rek J; Infectious Diseases Research Collaboration, Kampala, Uganda.
Hens N; I-Biostat, Data Science Institute, Hasselt University, Hasselt, Belgium.; Centre for Health Economics Research and Modelling Infectious Diseases, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium.
Kamya M; College of Health Sciences, Makerere University, Kampala, Uganda.; Infectious Diseases Research Collaboration, Kampala, Uganda.
Dorsey G; Department of Medicine, University of California, San Francisco, California, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Oct 23; Vol. 15 (10), pp. e0241033. Date of Electronic Publication: 2020 Oct 23 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Insecticides*
Organothiophosphorus Compounds*
Phenylcarbamates*
Malaria/*epidemiology
Mosquito Control/*methods
Child ; Child, Preschool ; Family Characteristics ; Humans ; Incidence ; Infant ; Malaria/transmission ; Uganda/epidemiology
Czasopismo naukowe
Tytuł :
Potential attenuation of biochemical parameters and enzymatic functions in Cyprinus carpio fingerlings by Phenthoate 50 EC insecticide exposure.
Autorzy :
Tabassum S; Department of Fisheries Biology and Genetics, Faculty of Fisheries, Bangladesh Agricultural University, Mymensingh, 2202, Bangladesh.
Rakhi SF; Department of Fisheries Biology and Genetics, Faculty of Fisheries, Bangladesh Agricultural University, Mymensingh, 2202, Bangladesh.; Upazilla Fisheries Office, Kasba, Brahmanbaria, Bangladesh.
Reza AHMM; Department of Fisheries Biology and Genetics, Faculty of Fisheries, Bangladesh Agricultural University, Mymensingh, 2202, Bangladesh.; School of Biological Science, College of Science and Engineering, Flinders University, Adelaide, Australia.
Mollah MFA; Department of Fisheries Biology and Genetics, Faculty of Fisheries, Bangladesh Agricultural University, Mymensingh, 2202, Bangladesh.
Hossain Z; Department of Fisheries Biology and Genetics, Faculty of Fisheries, Bangladesh Agricultural University, Mymensingh, 2202, Bangladesh. .
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2020 Oct; Vol. 27 (28), pp. 35837-35851. Date of Electronic Publication: 2020 Jun 30.
Typ publikacji :
Journal Article
MeSH Terms :
Carps*
Insecticides*
Organothiophosphorus Compounds*
Water Pollutants, Chemical*
Animals
Czasopismo naukowe
Tytuł :
Enantioselective disposition and metabolic products of isofenphos-methyl in rats and the hepatotoxic effects.
Autorzy :
Gao B; Department of Pesticide Science, College of Plant Protection, Nanjing Agricultural University, State and Local Joint Engineering Research Center of Green Pesticide Invention and Application, Nanjing, Jiangsu 210095, China.
Zhao S; Department of Pesticide Science, College of Plant Protection, Nanjing Agricultural University, State and Local Joint Engineering Research Center of Green Pesticide Invention and Application, Nanjing, Jiangsu 210095, China.
Shi H; Department of Pesticide Science, College of Plant Protection, Nanjing Agricultural University, State and Local Joint Engineering Research Center of Green Pesticide Invention and Application, Nanjing, Jiangsu 210095, China.
Zhang Z; Department of Pesticide Science, College of Plant Protection, Nanjing Agricultural University, State and Local Joint Engineering Research Center of Green Pesticide Invention and Application, Nanjing, Jiangsu 210095, China.
Li L; Department of Pesticide Science, College of Plant Protection, Nanjing Agricultural University, State and Local Joint Engineering Research Center of Green Pesticide Invention and Application, Nanjing, Jiangsu 210095, China.
He Z; Department of Pesticide Science, College of Plant Protection, Nanjing Agricultural University, State and Local Joint Engineering Research Center of Green Pesticide Invention and Application, Nanjing, Jiangsu 210095, China.
Wen Y; Department of Pesticide Science, College of Plant Protection, Nanjing Agricultural University, State and Local Joint Engineering Research Center of Green Pesticide Invention and Application, Nanjing, Jiangsu 210095, China.
Covaci A; Toxicological Center, University of Antwerp, Wilrijk, Belgium.
Wang M; Department of Pesticide Science, College of Plant Protection, Nanjing Agricultural University, State and Local Joint Engineering Research Center of Green Pesticide Invention and Application, Nanjing, Jiangsu 210095, China. Electronic address: .
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Źródło :
Environment international [Environ Int] 2020 Oct; Vol. 143, pp. 105940. Date of Electronic Publication: 2020 Jul 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Organothiophosphorus Compounds*/toxicity
Pesticides*
Animals ; Rats ; Rats, Sprague-Dawley ; Stereoisomerism
Czasopismo naukowe
Tytuł :
In Vitro Interaction of Organophosphono- and Organophosphorothioates with Human Acetylcholinesterase.
Autorzy :
Worek F; Bundeswehr Institute of Pharmacology and Toxicology, D-80937 Munich, Germany.
Thiermann H; Bundeswehr Institute of Pharmacology and Toxicology, D-80937 Munich, Germany.
Koller M; Bundeswehr Institute of Pharmacology and Toxicology, D-80937 Munich, Germany.
Wille T; Bundeswehr Institute of Pharmacology and Toxicology, D-80937 Munich, Germany.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Jul 02; Vol. 25 (13). Date of Electronic Publication: 2020 Jul 02.
Typ publikacji :
Journal Article
MeSH Terms :
Cholinesterase Inhibitors/*chemistry
Cholinesterase Inhibitors/*pharmacology
Organothiophosphorus Compounds/*chemistry
Organothiophosphorus Compounds/*pharmacology
Acetylcholinesterase/metabolism ; Cholinesterase Inhibitors/blood ; Cholinesterase Inhibitors/pharmacokinetics ; Cholinesterase Reactivators/pharmacology ; Drug Stability ; Humans ; Nerve Agents/chemistry ; Nerve Agents/pharmacology ; Obidoxime Chloride/chemistry ; Obidoxime Chloride/pharmacology ; Organothiophosphorus Compounds/blood ; Organothiophosphorus Compounds/pharmacokinetics ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Facile synthesis of carbon dots from Tagetes erecta as a precursor for determination of chlorpyrifos via fluorescence turn-off and quinalphos via fluorescence turn-on mechanisms.
Autorzy :
Ghosh S; Department of Chemistry, Research Institute of Chem-Bio Diagnostic Technology, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, Republic of Korea.
Gul AR; Department of Chemistry, Research Institute of Chem-Bio Diagnostic Technology, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, Republic of Korea.
Park CY; Department of Chemistry, Research Institute of Chem-Bio Diagnostic Technology, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, Republic of Korea.
Kim MW; Department of Chemistry, Research Institute of Chem-Bio Diagnostic Technology, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, Republic of Korea.
Xu P; Department of Chemistry, Research Institute of Chem-Bio Diagnostic Technology, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, Republic of Korea.
Baek SH; Department of Chemistry, Research Institute of Chem-Bio Diagnostic Technology, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, Republic of Korea.
Bhamore JR; Department of Chemistry, Research Institute of Chem-Bio Diagnostic Technology, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, Republic of Korea.
Kailasa SK; Department of Applied Chemistry, Sardar Vallabhbhai National Institute of Technology, Surat, 395 007, India. Electronic address: .
Park TJ; Department of Chemistry, Research Institute of Chem-Bio Diagnostic Technology, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, Republic of Korea. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2021 Sep; Vol. 279, pp. 130515. Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Chlorpyrifos*
Quantum Dots*
Tagetes*
Carbon ; Fluorescent Dyes ; Organothiophosphorus Compounds
Czasopismo naukowe
Tytuł :
Avoidance behavior of Eisenia fetida and Metaphire posthuma towards two different pesticides, acephate and atrazine.
Autorzy :
Datta S; Department of Zoology, Doaba College, Jalandhar, Punjab, 144001, India; School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab, 144402, India. Electronic address: .
Singh J; Department of Zoology, Khalsa College Amritsar, Punjab, 143002, India. Electronic address: .
Singh J; School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab, 144402, India.
Singh S; Interdisciplinary Centre for Water Research (ICwaR), Indian Institute of Science, Bangalore, Karnataka, 560012, India.
Singh S; Department of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar, 143005, India.
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Źródło :
Chemosphere [Chemosphere] 2021 Sep; Vol. 278, pp. 130476. Date of Electronic Publication: 2021 Apr 03.
Typ publikacji :
Journal Article
MeSH Terms :
Atrazine*/toxicity
Oligochaeta*
Pesticides*/toxicity
Soil Pollutants*/analysis
Soil Pollutants*/toxicity
Animals ; Avoidance Learning ; Organothiophosphorus Compounds ; Phosphoramides ; Soil
Czasopismo naukowe
Tytuł :
Organophosphorus pesticide quinalphos (Ekalux 25 E.C.) reduces sperm functional competence and decreases the fertilisation potential in Swiss albino mice.
Autorzy :
Kumari S; Department of Clinical Embryology, Central Research Lab, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.
Dcunha R; Department of Clinical Embryology, Central Research Lab, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.
Sanghvi SP; Department of Clinical Embryology, Central Research Lab, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.
Nayak G; Department of Clinical Embryology, Central Research Lab, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.
Kalthur SG; Department of Anatomy, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.
Raut SY; Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India.
Mutalik S; Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India.
Siddiqui S; Department of Biology, College of Sciences, King Khalid University, Kingdom of Saudi Arabia, Abha.
Alrumman SA; Department of Biology, College of Sciences, King Khalid University, Kingdom of Saudi Arabia, Abha.
Adiga SK; Department of Clinical Embryology, Central Research Lab, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.
Kalthur G; Department of Clinical Embryology, Central Research Lab, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.
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Źródło :
Andrologia [Andrologia] 2021 Sep; Vol. 53 (8), pp. e14115. Date of Electronic Publication: 2021 May 20.
Typ publikacji :
Journal Article
MeSH Terms :
Organophosphorus Compounds*
Pesticides*/toxicity
Animals ; Fertilization ; Male ; Mice ; Organothiophosphorus Compounds ; Sperm Motility ; Spermatozoa ; Testis
Czasopismo naukowe
Tytuł :
Detection of organophosphorus pesticides by nanogold/mercaptomethamidophos multi-residue electrochemical biosensor.
Autorzy :
Zhao G; Key Laboratory of Magnetic Molecules & Magnetic Information Materials Ministry of Education, The School of Chemistry and Material Science, College of Food Science, Shanxi Normal University, Linfen 041004, China. Electronic address: .
Zhou B; National and Local Joint Engineering Research Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.
Wang X; National and Local Joint Engineering Research Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.
Shen J; National and Local Joint Engineering Research Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.
Zhao B; National and Local Joint Engineering Research Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Aug 30; Vol. 354, pp. 129511. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Biosensing Techniques/*methods
Metal Nanoparticles/*chemistry
Organophosphorus Compounds/*chemistry
Organothiophosphorus Compounds/*chemistry
Pesticides/*analysis
Acetylcholinesterase/chemistry ; Acetylcholinesterase/metabolism ; Brassica/chemistry ; Brassica/metabolism ; Dielectric Spectroscopy ; Electrodes ; Enzymes, Immobilized/chemistry ; Enzymes, Immobilized/metabolism ; Gold/chemistry ; Limit of Detection
Czasopismo naukowe
Tytuł :
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Evaluate the Pharmacodynamic Effects of VX-150, a Highly Selective NaV1.8 Inhibitor, in Healthy Male Adults.
Autorzy :
Hijma HJ; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands.
Siebenga PS; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands.
de Kam ML; Centre for Human Drug Research, Leiden, The Netherlands.
Groeneveld GJ; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands.
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Źródło :
Pain medicine (Malden, Mass.) [Pain Med] 2021 Aug 06; Vol. 22 (8), pp. 1814-1826.
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Analgesics*/pharmacology
Pain Threshold*
Adolescent ; Adult ; Cross-Over Studies ; Dose-Response Relationship, Drug ; Double-Blind Method ; Humans ; Male ; Middle Aged ; Organothiophosphorus Compounds ; Young Adult
Czasopismo naukowe

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