Autor: "Osborne JM" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: A two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath.
Autorzy:: Dunn SJ; Department of Computer Science, University of Oxford, Oxford, United Kingdom. />Appleton PL
Nelson SA
Näthke IS
Gavaghan DJ
Osborne JM; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2012; Vol. 8 (5), pp. e1002515. Date of Electronic Publication: 2012 May 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Models, Biological*
Basement Membrane/*cytology
Basement Membrane/*physiology
Cell Communication/*physiology
Colon/*cytology
Colon/*physiology
Fibroblasts/*cytology
Fibroblasts/*physiology
Animals ; Computer Simulation ; Humans

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Skocz do pozycji: 2.

Tytuł:: Chaste: an open source C++ library for computational physiology and biology.
Autorzy:: Mirams GR; Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom. />Arthurs CJ
Bernabeu MO
Bordas R
Cooper J
Corrias A
Davit Y
Dunn SJ
Fletcher AG
Harvey DG
Marsh ME
Osborne JM
Pathmanathan P
Pitt-Francis J
Southern J
Zemzemi N
Gavaghan DJ; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2013; Vol. 9 (3), pp. e1002970. Date of Electronic Publication: 2013 Mar 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Databases, Factual*
Computational Biology/*methods
Computer Simulation ; Humans ; Models, Cardiovascular ; Neoplasms

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Skocz do pozycji: 3.

Tytuł:: Computational models reveal a passive mechanism for cell migration in the crypt.
Autorzy:: Dunn SJ; Computational Science Laboratory, Microsoft Research Ltd., Cambridge, United Kingdom.
Näthke IS
Osborne JM; Pokaż więcej
Źródło:: PloS one [PLoS One] 2013 Nov 18; Vol. 8 (11), pp. e80516. Date of Electronic Publication: 2013 Nov 18 (Print Publication: 2013).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Models, Biological*
Cell Movement/*physiology
Intestinal Mucosa/*cytology
Intestinal Mucosa/*physiology
Animals ; Cell Division ; Cell Proliferation ; Cell Size ; Computer Simulation ; Mice

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Skocz do pozycji: 4.

Tytuł:: The free energy landscape of dimerization of a membrane protein, NanC.
Autorzy:: Dunton TA; Department of Computer Science, University of Oxford, Oxford, United Kingdom.
Goose JE; Department of Biochemistry, University of Oxford, Oxford, United Kingdom.
Gavaghan DJ; Department of Computer Science, University of Oxford, Oxford, United Kingdom.
Sansom MS; Department of Biochemistry, University of Oxford, Oxford, United Kingdom.
Osborne JM; Department of Computer Science, University of Oxford, Oxford, United Kingdom.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2014 Jan; Vol. 10 (1), pp. e1003417. Date of Electronic Publication: 2014 Jan 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bacterial Outer Membrane Proteins/*metabolism
Escherichia coli/*metabolism
Escherichia coli Proteins/*metabolism
Lipid Bilayers/*chemistry
Porins/*metabolism
Models, Molecular ; Molecular Dynamics Simulation ; Phospholipids/chemistry ; Protein Conformation ; Protein Multimerization

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Skocz do pozycji: 5.

Tytuł:: Ten simple rules for effective computational research.
Autorzy:: Osborne JM; Computational Biology Group, Department of Computer Science, University of Oxford, Wolfson Building, Oxford, United Kingdom; Computational Science Laboratory, Microsoft Research, Cambridge, United Kingdom.
Bernabeu MO; CoMPLEX, Mathematical and Physical Sciences, University College London, Physics Building, London, United Kingdom; Centre for Computational Science, Department of Chemistry, University College London, London, United Kingdom.
Bruna M; Computational Biology Group, Department of Computer Science, University of Oxford, Wolfson Building, Oxford, United Kingdom; Computational Science Laboratory, Microsoft Research, Cambridge, United Kingdom.
Calderhead B; CoMPLEX, Mathematical and Physical Sciences, University College London, Physics Building, London, United Kingdom.
Cooper J; Computational Biology Group, Department of Computer Science, University of Oxford, Wolfson Building, Oxford, United Kingdom.
Dalchau N; Computational Science Laboratory, Microsoft Research, Cambridge, United Kingdom.
Dunn SJ; Computational Science Laboratory, Microsoft Research, Cambridge, United Kingdom.
Fletcher AG; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Andrew Wiles Building, Radcliffe Observatory Quarter, Oxford, United Kingdom.
Freeman R; Computational Science Laboratory, Microsoft Research, Cambridge, United Kingdom; CoMPLEX, Mathematical and Physical Sciences, University College London, Physics Building, London, United Kingdom.
Groen D; Centre for Computational Science, Department of Chemistry, University College London, London, United Kingdom.
Knapp B; Department of Statistics, University of Oxford, Oxford, United Kingdom.
McInerny GJ; Computational Biology Group, Department of Computer Science, University of Oxford, Wolfson Building, Oxford, United Kingdom; Computational Science Laboratory, Microsoft Research, Cambridge, United Kingdom.
Mirams GR; Computational Biology Group, Department of Computer Science, University of Oxford, Wolfson Building, Oxford, United Kingdom.
Pitt-Francis J; Computational Biology Group, Department of Computer Science, University of Oxford, Wolfson Building, Oxford, United Kingdom.
Sengupta B; The Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, United Kingdom.
Wright DW; CoMPLEX, Mathematical and Physical Sciences, University College London, Physics Building, London, United Kingdom; Centre for Computational Science, Department of Chemistry, University College London, London, United Kingdom.
Yates CA; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Andrew Wiles Building, Radcliffe Observatory Quarter, Oxford, United Kingdom.
Gavaghan DJ; Computational Biology Group, Department of Computer Science, University of Oxford, Wolfson Building, Oxford, United Kingdom.
Emmott S; Computational Science Laboratory, Microsoft Research, Cambridge, United Kingdom.
Deane C; Department of Statistics, University of Oxford, Oxford, United Kingdom.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2014 Mar 27; Vol. 10 (3), pp. e1003506. Date of Electronic Publication: 2014 Mar 27 (Print Publication: 2014).
Typ publikacji:: Editorial; Research Support, Non-U.S. Gov't
MeSH Terms:: Computational Biology/*methods
Computational Biology/*standards
Computer Simulation ; Computers ; Models, Statistical ; Software

Raport

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Skocz do pozycji: 6.

Tytuł:: Paneth Cell-Rich Regions Separated by a Cluster of Lgr5+ Cells Initiate Crypt Fission in the Intestinal Stem Cell Niche.
Autorzy:: Langlands AJ; Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Almet AA; School of Mathematics and Statistics, University of Melbourne, Victoria, Australia.
Appleton PL; Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Newton IP; Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Osborne JM; School of Mathematics and Statistics, University of Melbourne, Victoria, Australia.
Näthke IS; Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2016 Jun 27; Vol. 14 (6), pp. e1002491. Date of Electronic Publication: 2016 Jun 27 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Stem Cell Niche*
Intestinal Mucosa/*cytology
Paneth Cells/*cytology
Receptors, G-Protein-Coupled/*metabolism
Stem Cells/*cytology
Age Factors ; Animals ; Cell Adhesion ; Cell Count ; Cell Division ; Cell Proliferation ; Integrin beta4/metabolism ; Intestinal Mucosa/metabolism ; Intestine, Small/cytology ; Intestine, Small/metabolism ; Mice, Inbred C57BL ; Mice, Transgenic ; Microscopy, Confocal ; Models, Biological ; Organoids/cytology ; Organoids/metabolism ; Paneth Cells/metabolism ; Receptors, G-Protein-Coupled/genetics ; Stem Cells/metabolism

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Skocz do pozycji: 7.

Tytuł:: Validity of parent's self-reported responses to home safety questions.
Autorzy:: Osborne JM; a School of Medicine , Griffith University , Meadowbrook , Australia.
Shibl R; b School of Accountancy, Faculty of Business , Queensland University of Technology , Brisbane , Australia.
Cameron CM; c Centre of National Research on Disability and Rehabilitation Medicine, Griffith Health Institute , Griffith University , Meadowbrook , Australia.
Kendrick D; d School of Medicine, Division of Primary Care , University of Nottingham , Nottingham , United Kingdom.
Lyons RA; e Farr Institute of Health Informatics Research , Swansea University , Swansea , United Kingdom.
Spinks AB; a School of Medicine , Griffith University , Meadowbrook , Australia.; f Ecosystem Sciences , Commonwealth Scientific and Industrial Research Organisation (CSIRO) , Dutton Park , Australia.
Sipe N; g School of Geography, Planning and Environmental Management , The University of Queensland , St Lucia , Australia.
McClure RJ; h Harvard Injury Control Research Center , Harvard School of Public Health , Boston , USA.; Pokaż więcej
Źródło:: International journal of injury control and safety promotion [Int J Inj Contr Saf Promot] 2016 Sep; Vol. 23 (3), pp. 229-39. Date of Electronic Publication: 2015 Feb 26.
Typ publikacji:: Journal Article
MeSH Terms:: Family Characteristics*
Parents*/psychology
Safety/*statistics & numerical data
Accidents, Home/prevention & control ; Adult ; Australia/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Male ; Reproducibility of Results ; Safety/standards ; Self Report ; Sensitivity and Specificity ; Surveys and Questionnaires ; Young Adult

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Skocz do pozycji: 8.

Tytuł:: Comparing individual-based approaches to modelling the self-organization of multicellular tissues.
Autorzy:: Osborne JM; School of Mathematics and Statistics, University of Melbourne, Parkville, Victoria, Australia.
Fletcher AG; School of Mathematics and Statistics, University of Sheffield, Sheffield, United Kingdom.; Bateson Centre, University of Sheffield, Sheffield, United Kingdom.
Pitt-Francis JM; Department of Computer Science, University of Oxford, Oxford, United Kingdom.
Maini PK; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom.
Gavaghan DJ; Department of Computer Science, University of Oxford, Oxford, United Kingdom.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2017 Feb 13; Vol. 13 (2), pp. e1005387. Date of Electronic Publication: 2017 Feb 13 (Print Publication: 2017).
Typ publikacji:: Comparative Study; Evaluation Study; Journal Article
MeSH Terms:: Algorithms*
Models, Biological*
Cell Adhesion/*physiology
Cell Communication/*physiology
Cell Proliferation/*physiology
Spheroids, Cellular/*physiology
Animals ; Cell Movement/physiology ; Computer Simulation ; Humans

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Skocz do pozycji: 9.

Tytuł:: The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt.
Autorzy:: Kay SK; Department of Computer Science, University of Oxford, Oxford, U.K.
Harrington HA; Mathematical Institute, University of Oxford, Oxford, U.K.
Shepherd S; School of Mathematical Sciences, University of Nottingham, Nottingham, U.K.
Brennan K; Wellcome Trust Centre for Cell Matrix Research, University of Manchester, Manchester, U.K.
Dale T; School of Biosciences, Cardiff University, Cardiff, U.K.
Osborne JM; School of Mathematics and Statistics, University of Melbourne, Melbourne, Australia.
Gavaghan DJ; Department of Computer Science, University of Oxford, Oxford, U.K.
Byrne HM; Department of Computer Science, University of Oxford, Oxford, U.K.; Mathematical Institute, University of Oxford, Oxford, U.K.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2017 Feb 28; Vol. 13 (2), pp. e1005400. Date of Electronic Publication: 2017 Feb 28 (Print Publication: 2017).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Models, Biological*
Intestinal Mucosa/*metabolism
Receptors, Notch/*metabolism
Signal Transduction/*physiology
Transcription Factor HES-1/*metabolism
Wnt Signaling Pathway/*physiology
Biological Clocks/physiology ; Cells, Cultured ; Computer Simulation ; Humans ; Receptor Cross-Talk/physiology

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Skocz do pozycji: 10.

Tytuł:: Patterns of participation over four rounds of annual fecal immunochemical test-based screening for colorectal cancer: what predicts rescreening?
Autorzy:: Osborne JM; Bowel Health Service and Flinders Centre for Innovation in Cancer, Adelaide, Australia.; Flinders Centre for Innovation in Cancer, Flinders University of South Australia, GPO Box 2100, Adelaide, SA, 5001, Australia.
Wilson C; Flinders Centre for Innovation in Cancer, Flinders University of South Australia, GPO Box 2100, Adelaide, SA, 5001, Australia. .; Olivia Newton John Cancer, Wellness and Research Centre, Heidelberg, Victoria, 3084, Australia. .; School of Psychology and Public Health, La Trobe University, Bundoora, Victoria, 3086, Australia. .
Duncan A; Flinders Centre for Innovation in Cancer, Flinders University of South Australia, GPO Box 2100, Adelaide, SA, 5001, Australia.
Cole SR; Bowel Health Service and Flinders Centre for Innovation in Cancer, Adelaide, Australia.; Flinders Centre for Innovation in Cancer, Flinders University of South Australia, GPO Box 2100, Adelaide, SA, 5001, Australia.
Flight I; Flinders Centre for Innovation in Cancer, Flinders University of South Australia, GPO Box 2100, Adelaide, SA, 5001, Australia.; Olivia Newton John Cancer, Wellness and Research Centre, Heidelberg, Victoria, 3084, Australia.
Turnbull D; University of Adelaide, North Terrace, Adelaide, SA, 5005, Australia.
Hughes DL; Flinders Centre for Innovation in Cancer, Flinders University of South Australia, GPO Box 2100, Adelaide, SA, 5001, Australia.; Olivia Newton John Cancer, Wellness and Research Centre, Heidelberg, Victoria, 3084, Australia.
Young GP; Flinders Centre for Innovation in Cancer, Flinders University of South Australia, GPO Box 2100, Adelaide, SA, 5001, Australia.; Pokaż więcej
Źródło:: BMC public health [BMC Public Health] 2017 Aug 01; Vol. 18 (1), pp. 81. Date of Electronic Publication: 2017 Aug 01.
Typ publikacji:: Journal Article
MeSH Terms:: Occult Blood*
Colonoscopy/*statistics & numerical data
Colorectal Neoplasms/*diagnosis
Colorectal Neoplasms/*prevention & control
Early Detection of Cancer/*statistics & numerical data
Guideline Adherence/*statistics & numerical data
Mass Screening/*statistics & numerical data
Aged ; Australia/epidemiology ; Colorectal Neoplasms/epidemiology ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Surveys and Questionnaires

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