Autor: "Osborne JM" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt.
Autorzy:: Kay SK; Department of Computer Science, University of Oxford, Oxford, U.K.
Harrington HA; Mathematical Institute, University of Oxford, Oxford, U.K.
Shepherd S; School of Mathematical Sciences, University of Nottingham, Nottingham, U.K.
Brennan K; Wellcome Trust Centre for Cell Matrix Research, University of Manchester, Manchester, U.K.
Dale T; School of Biosciences, Cardiff University, Cardiff, U.K.
Osborne JM; School of Mathematics and Statistics, University of Melbourne, Melbourne, Australia.
Gavaghan DJ; Department of Computer Science, University of Oxford, Oxford, U.K.
Byrne HM; Department of Computer Science, University of Oxford, Oxford, U.K.; Mathematical Institute, University of Oxford, Oxford, U.K.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2017 Feb 28; Vol. 13 (2), pp. e1005400. Date of Electronic Publication: 2017 Feb 28 (Print Publication: 2017).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Models, Biological*
Intestinal Mucosa/*metabolism
Receptors, Notch/*metabolism
Signal Transduction/*physiology
Transcription Factor HES-1/*metabolism
Wnt Signaling Pathway/*physiology
Biological Clocks/physiology ; Cells, Cultured ; Computer Simulation ; Humans ; Receptor Cross-Talk/physiology

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Skocz do pozycji: 2.

Tytuł:: Paneth Cell-Rich Regions Separated by a Cluster of Lgr5+ Cells Initiate Crypt Fission in the Intestinal Stem Cell Niche.
Autorzy:: Langlands AJ; Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Almet AA; School of Mathematics and Statistics, University of Melbourne, Victoria, Australia.
Appleton PL; Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Newton IP; Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Osborne JM; School of Mathematics and Statistics, University of Melbourne, Victoria, Australia.
Näthke IS; Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2016 Jun 27; Vol. 14 (6), pp. e1002491. Date of Electronic Publication: 2016 Jun 27 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Stem Cell Niche*
Intestinal Mucosa/*cytology
Paneth Cells/*cytology
Receptors, G-Protein-Coupled/*metabolism
Stem Cells/*cytology
Age Factors ; Animals ; Cell Adhesion ; Cell Count ; Cell Division ; Cell Proliferation ; Integrin beta4/metabolism ; Intestinal Mucosa/metabolism ; Intestine, Small/cytology ; Intestine, Small/metabolism ; Mice, Inbred C57BL ; Mice, Transgenic ; Microscopy, Confocal ; Models, Biological ; Organoids/cytology ; Organoids/metabolism ; Paneth Cells/metabolism ; Receptors, G-Protein-Coupled/genetics ; Stem Cells/metabolism

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Skocz do pozycji: 3.

Tytuł:: Computational models reveal a passive mechanism for cell migration in the crypt.
Autorzy:: Dunn SJ; Computational Science Laboratory, Microsoft Research Ltd., Cambridge, United Kingdom.
Näthke IS
Osborne JM; Pokaż więcej
Źródło:: PloS one [PLoS One] 2013 Nov 18; Vol. 8 (11), pp. e80516. Date of Electronic Publication: 2013 Nov 18 (Print Publication: 2013).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Models, Biological*
Cell Movement/*physiology
Intestinal Mucosa/*cytology
Intestinal Mucosa/*physiology
Animals ; Cell Division ; Cell Proliferation ; Cell Size ; Computer Simulation ; Mice

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