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Tytuł :
Efficient mineralization and osteogenic gene overexpression of mesenchymal stem cells on decellularized spinach leaf scaffold.
Autorzy :
Salehi A; Department of Life Science, Faculty of New Science and Technology, University of Tehran, Tehran, Iran.
Mobarhan MA; Department of Life Science, Faculty of New Science and Technology, University of Tehran, Tehran, Iran.
Mohammadi J; Department of Life Science, Faculty of New Science and Technology, University of Tehran, Tehran, Iran. Electronic address: .
Shahsavarani H; Department of Cell and Molecular Sciences, Faculty of Life science and Biotechnology, Shahid Beheshti University, Tehran, Iran; Laboratory of Regenerative Medicine and Biomedical Innovations, Pasteur Institute of Iran, Tehran, Iran. Electronic address: .
Shokrgozar MA; National Cell Bank of Iran, Pasteur Institute of Iran, No. 69, Pasteur Ave, Tehran 1316943551, Iran.
Alipour A; Department of Nanobiotechnology, Pasteur Institute of Iran, No. 69, Pasteur Ave, Tehran 1316943551, Iran.
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Źródło :
Gene [Gene] 2020 Oct 05; Vol. 757, pp. 144852. Date of Electronic Publication: 2020 Jun 27.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Mesenchymal Stem Cells/*metabolism
Osteoblasts/*metabolism
Osteocalcin/*genetics
Plant Leaves/*chemistry
Tissue Scaffolds/*chemistry
Alkaline Phosphatase/genetics ; Alkaline Phosphatase/metabolism ; Biomineralization ; Calcium/metabolism ; Cell Line ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Core Binding Factor Alpha 1 Subunit/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Humans ; Mesenchymal Stem Cells/cytology ; Osteoblasts/cytology ; Osteocalcin/metabolism ; Spinacia oleracea/chemistry
Czasopismo naukowe
Tytuł :
Independent validation of experimental results requires timely and unrestricted access to animal models and reagents.
Autorzy :
Diegel CR; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Hann S; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Ayturk UM; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.; Musculoskeletal Integrity Program, Hospital for Special Surgery Research Institute, New York, New York, United States of America.
Hu JCW; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Lim KE; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Droscha CJ; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Madaj ZB; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Foxa GE; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Izaguirre I; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Robling AG; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Warman ML; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Williams BO; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
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Corporate Authors :
VAI Vivarium and Transgenics Core
Źródło :
PLoS genetics [PLoS Genet] 2020 Jun 26; Vol. 16 (6), pp. e1008940. Date of Electronic Publication: 2020 Jun 26 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Models, Animal*
Reproducibility of Results*
Hormones/*metabolism
Osteocalcin/*metabolism
Animals ; Bone and Bones/metabolism ; Hormones/genetics ; Humans ; Mice ; Mice, Knockout ; Osteocalcin/genetics ; Rats ; Rats, Transgenic ; Species Specificity
Czasopismo naukowe
Tytuł :
The facts of the matter: What is a hormone?
Autorzy :
Karsenty G; Department of Genetics and Development, Columbia University Irving Medical Center, New York, New York, United States of America.
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Źródło :
PLoS genetics [PLoS Genet] 2020 Jun 26; Vol. 16 (6), pp. e1008938. Date of Electronic Publication: 2020 Jun 26 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Hormones*
Osteocalcin*
Terminology as Topic*
Animals ; Bone and Bones/metabolism ; Humans ; Mice ; Models, Animal ; Species Specificity
Czasopismo naukowe
Tytuł :
Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass.
Autorzy :
Moriishi T; Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Ozasa R; Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan.
Ishimoto T; Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan.
Nakano T; Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan.
Hasegawa T; Department of Developmental Biology of Hard Tissue, Division of Oral Health Science, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Miyazaki T; Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Liu W; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Institute of Genetics and Cytology, Northeast Normal University, Changchun, China.
Fukuyama R; Laboratory of Pharmacology, Hiroshima International University, Kure, Japan.
Wang Y; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; College of Life and Environmental Science, Hangzhou Normal University, Hangzhou, China.
Komori H; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Qin X; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Amizuka N; Department of Developmental Biology of Hard Tissue, Division of Oral Health Science, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Komori T; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
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Źródło :
PLoS genetics [PLoS Genet] 2020 May 28; Vol. 16 (5), pp. e1008586. Date of Electronic Publication: 2020 May 28 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apatites/*metabolism
Calcification, Physiologic/*genetics
Carbohydrate Metabolism/*genetics
Glucose/*metabolism
Muscle, Skeletal/*growth & development
Osteocalcin/*physiology
Testosterone/*biosynthesis
Animals ; Apatites/chemistry ; Bone and Bones/metabolism ; Collagen/metabolism ; Crystallization ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle Development/genetics ; Muscle, Skeletal/metabolism ; Organ Size/genetics ; Osteoblasts/metabolism ; Osteocalcin/genetics ; Osteogenesis/genetics ; Testis/growth & development ; Testis/metabolism
Czasopismo naukowe
Tytuł :
An osteocalcin-deficient mouse strain without endocrine abnormalities.
Autorzy :
Diegel CR; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Hann S; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Ayturk UM; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.; Musculoskeletal Integrity Program, Hospital for Special Surgery Research Institute, New York, New York, United States of America.
Hu JCW; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Lim KE; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Droscha CJ; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Madaj ZB; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Foxa GE; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Izaguirre I; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Transgenics Core VVA; Vivarium and Transgenics Core, Van Andel Institute, Grand Rapids, Michigan, United States of America.
Paracha N; Department of Biology, Brooklyn College, Brooklyn, New York, United States of America.
Pidhaynyy B; Department of Biology, Brooklyn College, Brooklyn, New York, United States of America.
Dowd TL; Department of Chemistry, Brooklyn College, Brooklyn, New York, United States of America.; Ph.D. Program in Chemistry and Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, New York, New York, United States of America.
Robling AG; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Warman ML; Orthopedic Research Labs, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Williams BO; Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America.
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Źródło :
PLoS genetics [PLoS Genet] 2020 May 28; Vol. 16 (5), pp. e1008361. Date of Electronic Publication: 2020 May 28 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Endocrine System/*physiology
Osteocalcin/*genetics
Animals ; Bone Density/genetics ; Bone and Bones/metabolism ; Endocrine System/metabolism ; Female ; Fertility/genetics ; Insulin Resistance/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Osteocalcin/deficiency
Czasopismo naukowe
Tytuł :
Uncarboxylated osteocalcin ameliorates hepatic glucose and lipid metabolism in KKAy mice via activating insulin signaling pathway.
Autorzy :
Zhang XL; Medical School, University of Chinese Academy of Sciences, Beijing, 101400, China.; Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
Wang YN; Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
Ma LY; Medical School, University of Chinese Academy of Sciences, Beijing, 101400, China.
Liu ZS; Medical School, University of Chinese Academy of Sciences, Beijing, 101400, China.
Ye F; Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China. .
Yang JH; Medical School, University of Chinese Academy of Sciences, Beijing, 101400, China. .
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Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2020 Mar; Vol. 41 (3), pp. 383-393. Date of Electronic Publication: 2019 Oct 28.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Glucose/*metabolism
Diabetes Mellitus, Experimental/*metabolism
Insulin/*metabolism
Liver/*metabolism
Osteocalcin/*metabolism
Administration, Oral ; Animals ; Disease Models, Animal ; Female ; Glucose Tolerance Test ; Lipid Metabolism ; Mice ; Mice, Obese ; Osteocalcin/administration & dosage ; Signal Transduction
Czasopismo naukowe
Tytuł :
Iron Status in Elderly Women Impacts Myostatin, Adiponectin and Osteocalcin Levels Induced by Nordic Walking Training.
Autorzy :
Kortas J; Department of Sport, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Ziemann E; Department of Athletics, Strength and Conditioning, Poznan University of Physical Education, 61-871 Poznan, Poland.
Juszczak D; Seventh Navy Hospital, 80-305 Gdansk, Poland.
Micielska K; Department of Anatomy and Anthropology, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Kozłowska M; Department of Physiology and Pharmacology, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Prusik K; Department of Sport, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Prusik K; Department of Sport, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Antosiewicz J; Department of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, 80-210 Gdansk, Poland.
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Źródło :
Nutrients [Nutrients] 2020 Apr 17; Vol. 12 (4). Date of Electronic Publication: 2020 Apr 17.
Typ publikacji :
Journal Article
MeSH Terms :
Adiponectin/*metabolism
Iron/*metabolism
Myostatin/*metabolism
Osteocalcin/*metabolism
Physical Conditioning, Human/*physiology
Walking/*physiology
Adiponectin/blood ; Aged ; Aging/metabolism ; Female ; Ferritins/blood ; Ferritins/metabolism ; Humans ; Iron/blood ; Middle Aged ; Myostatin/blood ; Osteocalcin/blood ; Postmenopause/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
Experimental Acute Sepsis Reduced Number of Osteocalcin Immunolabeled Cells in Periodontal Ligament.
Autorzy :
Pinheiro GVVDS; UEPG - Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil.
Sabino-Silva R; Department of Physiology, Institute of Biomedical Sciences, UFU - Universidade Federal de Uberlândia, Uberlandia, MG, Brazil.
Araujo MR; UFPR - Universidade Federal do Paraná, Curitiba, PR, Brazil.
Gomes SP; UP - Universidade Positivo, Curitiba, PR, Brazil.
Oliveira SW; Department of Physiology, Institute of Biomedical Sciences, UFU - Universidade Federal de Uberlândia, Uberlandia, MG, Brazil.
Aguiar EMG; Department of Physiology, Institute of Biomedical Sciences, UFU - Universidade Federal de Uberlândia, Uberlandia, MG, Brazil.
Cardoso-Sousa L; Department of Physiology, Institute of Biomedical Sciences, UFU - Universidade Federal de Uberlândia, Uberlandia, MG, Brazil.
Gonzaga CC; UP - Universidade Positivo, Curitiba, PR, Brazil.
Claudino M; UEPG - Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brazil.
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Źródło :
Brazilian dental journal [Braz Dent J] 2020 Mar-Apr; Vol. 31 (2), pp. 143-151.
Typ publikacji :
Journal Article
MeSH Terms :
Osteocalcin*
Periodontal Ligament*
Sepsis*
Animals ; Disease Models, Animal ; Ligation ; Rats
Czasopismo naukowe
Tytuł :
Surface modification of titanium with collagen/hyaluronic acid and bone morphogenetic protein 2/7 heterodimer promotes osteoblastic differentiation.
Autorzy :
Wu C; Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Wenzhou Medical University.
Shao X; Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Wenzhou Medical University.
Lin X; Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Wenzhou Medical University.
Gao W; Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Wenzhou Medical University.
Fang Y; Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Wenzhou Medical University.
Wang J; Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Wenzhou Medical University.
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Źródło :
Dental materials journal [Dent Mater J] 2020 Dec 03; Vol. 39 (6), pp. 1072-1079. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Morphogenetic Protein 2*/metabolism
Titanium*
Alkaline Phosphatase/metabolism ; Bone Morphogenetic Protein 7 ; Cell Differentiation ; Collagen ; Hyaluronic Acid ; Osteoblasts/metabolism ; Osteocalcin
Czasopismo naukowe
Tytuł :
Irradiation with blue light-emitting diode enhances osteogenic differentiation of stem cells from the apical papilla.
Autorzy :
Yang Y; Southwest Medical University, Luzhou, 646000, China.; Hospital/School of Stomatology, Zunyi Medical University, Zunyi, 563000, China.
Zhu T; Yantai Stomatological Hospital, Yantai, 264000, China.
Wu Y; West China-Guang'an Hospital, Sichuan University, Guang'an, 638550, China.
Shu C; Southwest Medical University, Luzhou, 646000, China.
Chen Q; Southwest Medical University, Luzhou, 646000, China.
Yang J; Southwest Medical University, Luzhou, 646000, China.
Luo X; Southwest Medical University, Luzhou, 646000, China.
Wang Y; Hospital of Stomatology Southwest Medical University, Luzhou, 646000, China. .
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Źródło :
Lasers in medical science [Lasers Med Sci] 2020 Dec; Vol. 35 (9), pp. 1981-1988. Date of Electronic Publication: 2020 Mar 16.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation/*radiation effects
Dental Papilla/*cytology
Osteogenesis/*radiation effects
Stem Cells/*cytology
Stem Cells/*radiation effects
Alkaline Phosphatase/genetics ; Alkaline Phosphatase/metabolism ; Calcium/metabolism ; Cell Differentiation/genetics ; Cell Proliferation/genetics ; Cell Proliferation/radiation effects ; Cells, Cultured ; Dentinogenesis/genetics ; Dentinogenesis/radiation effects ; Extracellular Matrix Proteins/genetics ; Extracellular Matrix Proteins/metabolism ; Gene Expression Regulation/radiation effects ; Humans ; Osteocalcin/genetics ; Osteocalcin/metabolism ; Osteogenesis/genetics ; Phosphoproteins/genetics ; Phosphoproteins/metabolism ; Sialoglycoproteins/genetics ; Sialoglycoproteins/metabolism
Czasopismo naukowe
Tytuł :
Protective role of osteocalcin in diabetes pathogenesis.
Autorzy :
Desentis-Desentis MF; Laboratory of Tissue Engineering and Transplant, Department of Physiology, University Center for Health Sciences, University de Guadalajara, 950 Sierra Mojada St., Col. Independencia, C.P. 44340, Guadalajara, Jalisco, Mexico.; cGMP Cell Processing Facility, University Center for Health Sciences, University of Guadalajara, 950 Sierra Mojada St., Col. Independencia, C.P. 44340, Guadalajara, Jalisco, Mexico.
Rivas-Carrillo JD; Laboratory of Tissue Engineering and Transplant, Department of Physiology, University Center for Health Sciences, University de Guadalajara, 950 Sierra Mojada St., Col. Independencia, C.P. 44340, Guadalajara, Jalisco, Mexico.; cGMP Cell Processing Facility, University Center for Health Sciences, University of Guadalajara, 950 Sierra Mojada St., Col. Independencia, C.P. 44340, Guadalajara, Jalisco, Mexico.
Sánchez-Enríquez S; Department of Clinics, University Center of Los Altos, University of Guadalajara, 1200 Rafael Casillas Ave, ZC47620, Tepatitlán de Morelos, Jalisco, Mexico. .
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Źródło :
Journal of bone and mineral metabolism [J Bone Miner Metab] 2020 Nov; Vol. 38 (6), pp. 765-771. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Diabetes Mellitus/*metabolism
Osteocalcin/*metabolism
Protective Agents/*metabolism
Adipose Tissue/pathology ; Animals ; Homeostasis ; Humans ; Oxidative Stress
Czasopismo naukowe
Tytuł :
High bone turnover state under osteoporotic changes induces pain-like behaviors in mild osteoarthritis model mice.
Autorzy :
Kiyomoto K; Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.; Division of Occupational Therapy, Department of Rehabilitation, Japan Health Care College, 17-3, West-6 Megumino, Eniwa, 061-1373, Japan.
Iba K; Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan. .
Hanaka M; Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Ibe K; Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.; Division of Occupational Therapy, Department of Orthopedic Trauma Center, Sapporo Tokushukai Hospital, 1-1, Oyachi East-1, Atsubetsu-ku, Sapporo, 004-0041, Japan.
Hayakawa H; Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Teramoto A; Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Emori M; Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Yamashita T; Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
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Źródło :
Journal of bone and mineral metabolism [J Bone Miner Metab] 2020 Nov; Vol. 38 (6), pp. 806-818. Date of Electronic Publication: 2020 Jul 12.
Typ publikacji :
Journal Article
MeSH Terms :
Behavior, Animal*
Bone Remodeling*/drug effects
Osteoarthritis/*complications
Osteoporosis/*complications
Osteoporosis/*physiopathology
Pain/*etiology
Animals ; Cartilage/pathology ; Cell Differentiation/drug effects ; Cell Differentiation/genetics ; Cyclooxygenase Inhibitors/pharmacology ; Diphosphonates/pharmacology ; Disease Models, Animal ; Female ; Gene Expression Regulation/drug effects ; Iodoacetates ; Male ; Mice, Inbred C57BL ; Osteoarthritis/blood ; Osteoarthritis/pathology ; Osteoarthritis/physiopathology ; Osteoblasts/drug effects ; Osteoblasts/metabolism ; Osteoblasts/pathology ; Osteocalcin/genetics ; Osteocalcin/metabolism ; Osteoclasts/drug effects ; Osteoclasts/metabolism ; Osteoclasts/pathology ; Osteoporosis/blood ; Ovariectomy ; Pain/blood ; Tartrate-Resistant Acid Phosphatase/blood ; X-Ray Microtomography
Czasopismo naukowe
Tytuł :
Maximal dose-response of vitamin-K2 (menaquinone-4) on undercarboxylated osteocalcin in women with osteoporosis.
Autorzy :
K Giri T; Department of Medicine, Washington University in Saint Louis, Missouri.
Newton D; Department of Medicine, Washington University in Saint Louis, Missouri.; Cleveland Clinic, Cleveland, Ohio.
Chaudhary O; Department of Medicine, Washington University in Saint Louis, Missouri.
Deych E; Department of Medicine, Washington University in Saint Louis, Missouri.
Napoli N; Department of Medicine, Washington University in Saint Louis, Missouri.; Univeristà campus Bio-Medico di Roma, Italy.
Villareal R; Department of Medicine, Washington University in Saint Louis, Missouri.; Baylor College of Medicine, Houston, Texas.
Diemer K; Department of Medicine, Washington University in Saint Louis, Missouri.
E Milligan P; Department of Medicine, Washington University in Saint Louis, Missouri.; BJC Healthcare System, Missouri.
F Gage B; Department of Medicine, Washington University in Saint Louis, Missouri.
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Źródło :
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition [Int J Vitam Nutr Res] 2020 Jan; Vol. 90 (1-2), pp. 42-48. Date of Electronic Publication: 2019 Feb 28.
Typ publikacji :
Journal Article
MeSH Terms :
Fractures, Compression*
Osteoporosis*
Spinal Fractures*
Osteocalcin/*blood
Vitamin K 2/*analogs & derivatives
Vitamin K 2/*metabolism
Female ; Humans ; Osteocalcin/chemistry ; Prospective Studies ; Vitamin K 2/administration & dosage ; Vitamin K 2/therapeutic use ; Vitamins/administration & dosage ; Vitamins/metabolism
Czasopismo naukowe
Tytuł :
Mediation of the Acute Stress Response by the Skeleton.
Autorzy :
Berger JM; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA; Program in Microbiology, Immunology and Infection, Columbia University Irving Medical Center, New York, NY 10032, USA.
Singh P; Metabolic Research Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India.
Khrimian L; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA.
Morgan DA; Department of Pharmacology, University of Iowa and Veteran Health Care System, Iowa City, IA 52242, USA.
Chowdhury S; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA.
Arteaga-Solis E; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA; Division of Pediatric Pulmonary, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY 10032, USA.
Horvath TL; Program in Integrative Cell Signaling and Neurobiology of Metabolism, Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA.
Domingos AI; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Marsland AL; Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Yadav VK; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA; Metabolic Research Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India.
Rahmouni K; Department of Pharmacology, University of Iowa and Veteran Health Care System, Iowa City, IA 52242, USA.
Gao XB; Program in Integrative Cell Signaling and Neurobiology of Metabolism, Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA.
Karsenty G; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA. Electronic address: .
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Źródło :
Cell metabolism [Cell Metab] 2019 Nov 05; Vol. 30 (5), pp. 890-902.e8. Date of Electronic Publication: 2019 Sep 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Bone and Bones/*metabolism
Osteoblasts/*metabolism
Osteocalcin/*blood
Stress, Physiological/*genetics
Adrenal Insufficiency/metabolism ; Adrenalectomy ; Adult ; Animals ; Cells, Cultured ; Female ; Glutamic Acid/metabolism ; Healthy Volunteers ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Middle Aged ; Neurons/metabolism ; Osteocalcin/genetics ; Parasympathetic Nervous System/cytology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Osteocalcin affects bone mineral and mechanical properties in female mice.
Autorzy :
Berezovska O; Department of Chemistry, Brooklyn College, Brooklyn, NY 11210, United States of America.
Yildirim G; Department of Chemistry, Brooklyn College, Brooklyn, NY 11210, United States of America.
Budell WC; Department of Biology, Brooklyn College, Brooklyn, NY 11210, United States of America.
Yagerman S; Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY, United States of America; Sibley School of Mechanical & Aerospace Engineering, Cornell University, Ithaca, NY, United States of America.
Pidhaynyy B; Department of Biology, Brooklyn College, Brooklyn, NY 11210, United States of America.
Bastien C; Department of Chemistry, Brooklyn College, Brooklyn, NY 11210, United States of America.
van der Meulen MCH; Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY, United States of America; Research Division, Hospital for Special Surgery, NY, NY, United States of America; Sibley School of Mechanical & Aerospace Engineering, Cornell University, Ithaca, NY, United States of America.
Dowd TL; Department of Chemistry, Brooklyn College, Brooklyn, NY 11210, United States of America; Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States of America; Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States of America. Electronic address: .
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Źródło :
Bone [Bone] 2019 Nov; Vol. 128, pp. 115031. Date of Electronic Publication: 2019 Aug 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Calcification, Physiologic/*physiology
Osteocalcin/*metabolism
Animals ; Bone Density/physiology ; Calcification, Physiologic/genetics ; Female ; Mice, Inbred C57BL ; Mice, Knockout ; Osteocalcin/genetics ; Spectroscopy, Fourier Transform Infrared ; Stress, Mechanical ; X-Ray Microtomography
Czasopismo naukowe
Tytuł :
Exosomes secreted from osteocalcin-overexpressing endothelial progenitor cells promote endothelial cell angiogenesis.
Autorzy :
Yi M; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, People's Republic of China.; Beijing Key Laboratory of Metabolic Disorder Related Cardiovascular Disease, Beijing, People's Republic of China.
Wu Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, People's Republic of China.; Beijing Key Laboratory of Metabolic Disorder Related Cardiovascular Disease, Beijing, People's Republic of China.
Long J; Department of Immunology, School of Basic Medical Sciences, Capital Medical University, Beijing, People's Republic of China.
Liu F; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Liu Z; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Zhang YH; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Sun XP; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Fan ZX; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Gao J; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Si J; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Zuo XB; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Zhang LM; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Shi N; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Miao ZP; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Bai ZR; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Liu BY; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Liu HR; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, People's Republic of China.; Beijing Key Laboratory of Metabolic Disorder Related Cardiovascular Disease, Beijing, People's Republic of China.
Li J; Division of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.; Beijing Key Laboratory of Metabolic Disorder Related Cardiovascular Disease, Beijing, People's Republic of China.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2019 Nov 01; Vol. 317 (5), pp. C932-C941. Date of Electronic Publication: 2019 Aug 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation/*physiology
Endothelial Progenitor Cells/*metabolism
Exosomes/*metabolism
Neovascularization, Physiologic/*physiology
Osteocalcin/*biosynthesis
Animals ; Cell Movement/physiology ; Gene Expression ; Osteocalcin/genetics ; Rats
Czasopismo naukowe
Tytuł :
The Effect of Recombinant Undercarboxylated Osteocalcin on Endothelial Dysfunction.
Autorzy :
Qaradakhi T; Institute for Health and Sport, Victoria University, Melbourne, VIC, 8001, Australia. .
Gadanec LK; Institute for Health and Sport, Victoria University, Melbourne, VIC, 8001, Australia.
Tacey AB; Institute for Health and Sport, Victoria University, Melbourne, VIC, 8001, Australia.; Australian Institute for Musculoskeletal Science (AIMSS), University of Melbourne and Western Health, St Albans, VIC, 3021, Australia.
Hare DL; Department of Cardiology, Austin Health, University of Melbourne, Heidelberg, VIC, 3084, Australia.
Buxton BF; University of Melbourne, Consultant in Cardiac Surgery, Melbourne, VIC, Australia.
Apostolopoulos V; Institute for Health and Sport, Victoria University, Melbourne, VIC, 8001, Australia.
Levinger I; Institute for Health and Sport, Victoria University, Melbourne, VIC, 8001, Australia.; Australian Institute for Musculoskeletal Science (AIMSS), University of Melbourne and Western Health, St Albans, VIC, 3021, Australia.
Zulli A; Institute for Health and Sport, Victoria University, Melbourne, VIC, 8001, Australia.
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Źródło :
Calcified tissue international [Calcif Tissue Int] 2019 Nov; Vol. 105 (5), pp. 546-556. Date of Electronic Publication: 2019 Sep 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronary Artery Disease*/metabolism
Endothelium, Vascular/*drug effects
Osteocalcin/*pharmacology
Vasodilation/*drug effects
Animals ; Humans ; Osteocalcin/metabolism ; Rabbits ; Receptors, G-Protein-Coupled/metabolism ; Recombinant Proteins/metabolism ; Recombinant Proteins/pharmacology
Czasopismo naukowe
Tytuł :
Predictive value of the bone markers osteocalcin and C-terminal telopeptide for jaw osteonecrosis in high-risk prostate cancer patients on bisphosphonate therapy: A prospective study.
Autorzy :
Delaka A; Oral Surgeon. Medical School of Athens. Paleo Faliro. Athens. Greece.
Mourmouras N; Consultant Urologist. Asklepieion Hospital of Athens. Greece.
Zervou-Valvi F; Director of Dental Department. Asklepieion Hospital of Athens. Greece.
Stravodimos K; Associate Professor of Urology. Laikon University Hospital of Athens. Greece.
Anastasiou I; Assistant Professor of Urology. Laikon University Hospital of Athens. Greece.
Delakas D; Director of Urology Department. Asklepieion Hospital of Athens. Voula. Athens. Greece.
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Transliterated Title :
Valor predictivo de los marcadores oseos osteocalcina y telopéptido C terminal para la osteonecrosis mandibular en pacientes con cáncer de próstata (CaP) de alto riesgo bajo tratamiento con bifosfonatos: estudio prospectivo.
Źródło :
Archivos espanoles de urologia [Arch Esp Urol] 2019 Nov; Vol. 72 (9), pp. 948-954.
Typ publikacji :
Journal Article
MeSH Terms :
Bisphosphonate-Associated Osteonecrosis of the Jaw*/diagnosis
Bone Density Conservation Agents*/therapeutic use
Osteocalcin*/blood
Peptides*/blood
Prostatic Neoplasms*/drug therapy
Androgen Antagonists ; Collagen Type I ; Diphosphonates ; Humans ; Male ; Predictive Value of Tests ; Prospective Studies
Czasopismo naukowe
Tytuł :
Silicon supplementation affects mineral metabolism but not bone density or strength in male broilers.
Autorzy :
Pritchard A; Department of Animal Science, Michigan State University, East Lansing, Michigan, United States of America.
Robison C; Department of Animal Science, Michigan State University, East Lansing, Michigan, United States of America.
Nguyen T; Department of Animal Science, Michigan State University, East Lansing, Michigan, United States of America.
Nielsen BD; Department of Animal Science, Michigan State University, East Lansing, Michigan, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Dec 07; Vol. 15 (12), pp. e0243007. Date of Electronic Publication: 2020 Dec 07 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Density/*drug effects
Bone and Bones/*physiology
Silicon/*administration & dosage
Amino Acids/blood ; Animal Feed/analysis ; Animals ; Body Weight/drug effects ; Bone and Bones/diagnostic imaging ; Bone and Bones/drug effects ; Chickens ; Dietary Supplements ; Male ; Osteocalcin/blood ; Random Allocation ; Silicon/pharmacology ; Tomography, X-Ray Computed
Czasopismo naukowe

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