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Tytuł :
Effect of electroacupuncture on the kisspeptin system in a pubertal rat model of polycystic ovary syndrome.
Autorzy :
Wang Z; Department of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
Yang L; Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
Dong H; Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
Dong H; Department of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
Cheng L; Department of Acupuncture and Moxibustion, East Hospital, Tongji University, Shanghai, China.
Yi P; Department of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
Huang D; Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
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Źródło :
Acupuncture in medicine : journal of the British Medical Acupuncture Society [Acupunct Med] 2021 Oct; Vol. 39 (5), pp. 491-500. Date of Electronic Publication: 2021 Jan 07.
Typ publikacji :
Journal Article
MeSH Terms :
Electroacupuncture*
Kisspeptins/*metabolism
Polycystic Ovary Syndrome/*metabolism
Polycystic Ovary Syndrome/*therapy
Acupuncture Points ; Animals ; Dynorphins/genetics ; Dynorphins/metabolism ; Estrous Cycle ; Female ; Follicle Stimulating Hormone/metabolism ; Humans ; Hypothalamus/metabolism ; Kisspeptins/genetics ; Luteinizing Hormone/metabolism ; Neurokinin B/genetics ; Neurokinin B/metabolism ; Ovary/metabolism ; Polycystic Ovary Syndrome/genetics ; Polycystic Ovary Syndrome/physiopathology ; Pregnancy ; Puberty/metabolism ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Downregulating lncRNA NEAT1 induces proliferation and represses apoptosis of ovarian granulosa cells in polycystic ovary syndrome via microRNA-381/IGF1 axis.
Autorzy :
Zhen J; Department of Gynecological Endocrinology and Reproduction Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 41 Damucang Hutong, Xicheng, Beijing, China.
Li J; Department of Obstetrics and Gynecology, Zhongguancun Hospital, Beijing, 100080, China.
Li X; Community Health Service Center, Beijing Forestry University, Beijing, 100053, China.
Wang X; Department of Gynecological Endocrinology and Reproduction Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 41 Damucang Hutong, Xicheng, Beijing, China.
Xiao Y; Department of Gynecological Endocrinology and Reproduction Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 41 Damucang Hutong, Xicheng, Beijing, China.
Sun Z; Department of Gynecological Endocrinology and Reproduction Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 41 Damucang Hutong, Xicheng, Beijing, China. .
Yu Q; Department of Gynecological Endocrinology and Reproduction Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 41 Damucang Hutong, Xicheng, Beijing, China. .
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Źródło :
Journal of biomedical science [J Biomed Sci] 2021 Jul 15; Vol. 28 (1), pp. 53. Date of Electronic Publication: 2021 Jul 15.
Typ publikacji :
Journal Article
MeSH Terms :
Down-Regulation*
Apoptosis/*genetics
Cell Proliferation/*genetics
MicroRNAs/*genetics
Polycystic Ovary Syndrome/*genetics
RNA, Long Noncoding/*genetics
Animals ; Female ; Granulosa Cells/metabolism ; MicroRNAs/metabolism ; Ovary/metabolism ; Polycystic Ovary Syndrome/metabolism ; RNA, Long Noncoding/metabolism ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Ovarian Hyperandrogenism and Response to Gonadotropin-releasing Hormone Analogues in Primary Severe Insulin Resistance.
Autorzy :
Huang-Doran I; University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, UK.
Kinzer AB; Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, MD, USA.
Jimenez-Linan M; Histopathology Department, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Thackray K; University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, UK.
Harris J; University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, UK.
Adams CL; University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, UK.
de Kerdanet M; Pediatric Endocrinology Unit, University Hospital, Rennes, France.
Stears A; National Severe Insulin Resistance Service, Wolfson Diabetes & Endocrine Clinic, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
O'Rahilly S; University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, UK.
Savage DB; University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, UK.
Gorden P; Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, MD, USA.
Brown RJ; Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, MD, USA.
Semple RK; University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.; Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2021 Jul 13; Vol. 106 (8), pp. 2367-2383.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Fertility Agents, Female/*therapeutic use
Gonadotropin-Releasing Hormone/*analogs & derivatives
Hyperandrogenism/*drug therapy
Insulin Resistance/*physiology
Ovary/*drug effects
Testosterone/*blood
Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Female ; Humans ; Hyperandrogenism/metabolism ; Infant ; Insulin/blood ; Lipodystrophy/drug therapy ; Lipodystrophy/metabolism ; Middle Aged ; Ovary/metabolism ; Polycystic Ovary Syndrome/drug therapy ; Polycystic Ovary Syndrome/metabolism ; Retrospective Studies ; Sex Hormone-Binding Globulin ; Young Adult
Czasopismo naukowe
Tytuł :
Uterine anomalies in cell proliferation, energy homeostasis and oxidative stress in PCOS hamsters, M. auratus: Therapeutic potentials of melatonin.
Autorzy :
Hansda SR; Pineal Research Laboratory, Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh 221005, India. Electronic address: .
Haldar C; Pineal Research Laboratory, Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh 221005, India. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Sep 15; Vol. 281, pp. 119755. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Proliferation/*drug effects
Energy Metabolism/*drug effects
Homeostasis/*drug effects
Melatonin/*therapeutic use
Oxidative Stress/*drug effects
Polycystic Ovary Syndrome/*drug therapy
Uterus/*pathology
Animals ; Aromatase Inhibitors/administration & dosage ; Aromatase Inhibitors/pharmacology ; Aromatase Inhibitors/therapeutic use ; Blood Glucose/metabolism ; Cricetinae ; Disease Models, Animal ; Female ; Gonadal Steroid Hormones/blood ; Infertility, Female/drug therapy ; Insulin/blood ; Insulin Resistance ; Letrozole/administration & dosage ; Letrozole/pharmacology ; Letrozole/therapeutic use ; Melatonin/administration & dosage ; Melatonin/pharmacology ; Mesocricetus ; Mice ; Ovary/pathology ; Polycystic Ovary Syndrome/metabolism ; Polycystic Ovary Syndrome/pathology ; Uterus/metabolism
Czasopismo naukowe
Tytuł :
Potential Health Benefits of Curcumin on Female Reproductive Disorders: A Review.
Autorzy :
Kamal DAM; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu 88400, Malaysia.
Salamt N; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Yusuf ANM; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu 88400, Malaysia.
Kashim MIAM; Centre of Shariah, Faculty of Islamic Studies, Universiti Kebangsaan Malaysia, Bangi 43600, Malaysia.; Insitute of Islam Hadhari, Universiti Kebangsaan Malaysia, Bangi 43600, Malaysia.
Mokhtar MH; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
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Źródło :
Nutrients [Nutrients] 2021 Sep 07; Vol. 13 (9). Date of Electronic Publication: 2021 Sep 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Phytotherapy*
Curcumin/*pharmacology
Endometriosis/*drug therapy
Polycystic Ovary Syndrome/*drug therapy
Primary Ovarian Insufficiency/*drug therapy
Animals ; Anti-Inflammatory Agents/pharmacology ; Antioxidants/pharmacology ; Curcuma/chemistry ; Female ; Humans ; Ovary/drug effects ; Oxidative Stress/drug effects ; Rhizome/chemistry
Czasopismo naukowe
Tytuł :
Effects of total flavonoids from Eucommia ulmoides Oliv. leaves on polycystic ovary syndrome with insulin resistance model rats induced by letrozole combined with a high-fat diet.
Autorzy :
Peng MF; National International Cooperation Base of Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Electronic address: .
Tian S; National International Cooperation Base of Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Electronic address: .
Song YG; National International Cooperation Base of Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Electronic address: .
Li CX; Immunopharmacology Laboratory of Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Electronic address: .
Miao MS; National International Cooperation Base of Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Electronic address: .
Ren Z; National International Cooperation Base of Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Electronic address: .
Li M; National International Cooperation Base of Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Jun 12; Vol. 273, pp. 113947. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Journal Article
MeSH Terms :
Diet, High-Fat*/adverse effects
Insulin Resistance*
Eucommiaceae/*chemistry
Flavonoids/*pharmacology
Plant Extracts/*pharmacology
Polycystic Ovary Syndrome/*drug therapy
Animals ; Body Weight/drug effects ; Disease Models, Animal ; Female ; Flavonoids/chemistry ; Flavonoids/therapeutic use ; Gonadal Steroid Hormones/blood ; Hypothalamus/drug effects ; Insulin-Like Growth Factor I/metabolism ; Kisspeptins/metabolism ; Letrozole/toxicity ; Metformin/pharmacology ; Metformin/therapeutic use ; Ovary/drug effects ; Pancreas/drug effects ; Phosphatidylinositol 3-Kinases/metabolism ; Pituitary Gland/drug effects ; Plant Extracts/therapeutic use ; Plant Leaves/chemistry ; Polycystic Ovary Syndrome/blood ; Polycystic Ovary Syndrome/chemically induced ; Polycystic Ovary Syndrome/pathology ; Proto-Oncogene Proteins c-akt/metabolism ; Rats, Sprague-Dawley ; Receptors, Androgen/metabolism ; Receptors, Leptin/metabolism
Czasopismo naukowe
Tytuł :
Effect of vitamin D on experimental model of polycystic ovary syndrome in female rats.
Autorzy :
Helal BAF; Tanta Faculty of Medicine, Department of Physiology, Egypt. Electronic address: .
Ismail GM; Tanta Faculty of Medicine, Department of Physiology, Egypt.
Nassar SE; Tanta Faculty of Medicine, Department of Physiology, Egypt.
Zeid AAA; Tanta Faculty of Medicine, Department of Physiology, Egypt.
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Źródło :
Life sciences [Life Sci] 2021 Oct 15; Vol. 283, pp. 119558. Date of Electronic Publication: 2021 Apr 27.
Typ publikacji :
Journal Article
MeSH Terms :
Ovary/*metabolism
Oxidative Stress/*drug effects
Polycystic Ovary Syndrome/*metabolism
Vitamin D/*pharmacology
Animals ; Caspase 3/metabolism ; Disease Models, Animal ; Female ; Letrozole/adverse effects ; Letrozole/pharmacology ; Ovary/pathology ; Polycystic Ovary Syndrome/chemically induced ; Polycystic Ovary Syndrome/pathology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Addressing the role of 11β-hydroxysteroid dehydrogenase type 1 in the development of polycystic ovary syndrome and the putative therapeutic effects of its selective inhibition in a preclinical model.
Autorzy :
Li X; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Hu S; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Zhu Q; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Yao G; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Yao J; Animal Laboratory, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China.
Li J; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Wang Y; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Ding Y; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Qi J; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Xu R; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Zhao H; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Zhu Z; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Du Y; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Sun K; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Sun Y; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China. Electronic address: .
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Źródło :
Metabolism: clinical and experimental [Metabolism] 2021 Jun; Vol. 119, pp. 154749. Date of Electronic Publication: 2021 Mar 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
11-beta-Hydroxysteroid Dehydrogenase Type 1/*antagonists & inhibitors
11-beta-Hydroxysteroid Dehydrogenase Type 1/*physiology
Piperazines/*therapeutic use
Polycystic Ovary Syndrome/*drug therapy
Sulfonamides/*therapeutic use
Thiazoles/*therapeutic use
11-beta-Hydroxysteroid Dehydrogenase Type 1/metabolism ; Animals ; Cells, Cultured ; Disease Models, Animal ; Drug Evaluation, Preclinical ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use ; Female ; Humans ; Infertility, Female/drug therapy ; Infertility, Female/metabolism ; Infertility, Female/pathology ; Insulin Resistance/physiology ; Ovary/enzymology ; Ovary/metabolism ; Piperazines/pharmacology ; Polycystic Ovary Syndrome/etiology ; Polycystic Ovary Syndrome/metabolism ; Polycystic Ovary Syndrome/pathology ; Rats ; Rats, Sprague-Dawley ; Sulfonamides/pharmacology ; Thiazoles/pharmacology
Czasopismo naukowe
Tytuł :
Comparison of PCOS phenotypes in adolescent and young adult Mediterranean women with possible PCOS.
Autorzy :
Fruzzetti F; Department of Obstetrics and Gynecology, Ospedale Santa Chiara, University of Pisa, Via Roma 35, 56100, Pisa, Italy. .
Baldari F; Department of Obstetrics and Gynecology, Ospedale Santa Chiara, University of Pisa, Via Roma 35, 56100, Pisa, Italy.
Palla G; Department of Obstetrics and Gynecology, Ospedale Santa Chiara, University of Pisa, Via Roma 35, 56100, Pisa, Italy.
Fidecicchi T; Department of Obstetrics and Gynecology, Ospedale Santa Chiara, University of Pisa, Via Roma 35, 56100, Pisa, Italy.
Carmina E; Department of Endocrinology, Medical School of Palermo University, University of Palermo, Palermo, Italy.
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Źródło :
Journal of endocrinological investigation [J Endocrinol Invest] 2021 May; Vol. 44 (5), pp. 995-1000. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Journal Article
MeSH Terms :
Hirsutism*/diagnosis
Hirsutism*/metabolism
Polycystic Ovary Syndrome*/diagnosis
Polycystic Ovary Syndrome*/epidemiology
Polycystic Ovary Syndrome*/metabolism
Polycystic Ovary Syndrome*/physiopathology
Androgens/*blood
Menarche/*metabolism
Ovary/*diagnostic imaging
Adolescent ; Body Mass Index ; Early Diagnosis ; Female ; Humans ; Italy/epidemiology ; Phenotype ; Prevalence ; Ultrasonography/methods ; Young Adult
Czasopismo naukowe
Tytuł :
Influence of ethnicity on different aspects of polycystic ovary syndrome: a systematic review.
Autorzy :
Sendur SN; Division of Endocrinology and Metabolism, Department of Internal Medicine, Hacettepe University School of Medicine, Hacettepe Ankara, Turkey.
Yildiz BO; Division of Endocrinology and Metabolism, Department of Internal Medicine, Hacettepe University School of Medicine, Hacettepe Ankara, Turkey. Electronic address: .
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Źródło :
Reproductive biomedicine online [Reprod Biomed Online] 2021 Apr; Vol. 42 (4), pp. 799-818. Date of Electronic Publication: 2020 Dec 16.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Polycystic Ovary Syndrome/*ethnology
Female ; Humans ; Hyperandrogenism/ethnology ; Menstruation Disturbances/ethnology ; Ovary/pathology ; Polycystic Ovary Syndrome/metabolism ; Polycystic Ovary Syndrome/pathology ; Polycystic Ovary Syndrome/psychology
Czasopismo naukowe
Tytuł :
Vaspin, a novel adipokine in woman granulosa cells physiology and PCOS pathogenesis?
Autorzy :
Bongrani A; UMR 85 Physiology of Reproduction and Behaviour, National Research Institute for Agriculture, Food and Environment (INRAE) Centre Val de Loire, Nouzilly, France.
Mellouk N; UMR 85 Physiology of Reproduction and Behaviour, National Research Institute for Agriculture, Food and Environment (INRAE) Centre Val de Loire, Nouzilly, France.
Ramé C; UMR 85 Physiology of Reproduction and Behaviour, National Research Institute for Agriculture, Food and Environment (INRAE) Centre Val de Loire, Nouzilly, France.
Cornuau M; Department of Reproductive Medicine and Biology, University Hospital of Tours, Tours, France.
Guerif F; UMR 85 Physiology of Reproduction and Behaviour, National Research Institute for Agriculture, Food and Environment (INRAE) Centre Val de Loire, Nouzilly, France.; Department of Reproductive Medicine and Biology, University Hospital of Tours, Tours, France.
Froment P; UMR 85 Physiology of Reproduction and Behaviour, National Research Institute for Agriculture, Food and Environment (INRAE) Centre Val de Loire, Nouzilly, France.
Dupont J; UMR 85 Physiology of Reproduction and Behaviour, National Research Institute for Agriculture, Food and Environment (INRAE) Centre Val de Loire, Nouzilly, France.
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Źródło :
The Journal of endocrinology [J Endocrinol] 2021 Apr; Vol. 249 (1), pp. 57-70.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Granulosa Cells/*physiology
Heat-Shock Proteins/*physiology
Polycystic Ovary Syndrome/*physiopathology
Serpins/*physiology
Adult ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Female ; Fertilization in Vitro ; Follicular Fluid/chemistry ; France ; Gene Expression ; Granulosa Cells/chemistry ; Granulosa Cells/drug effects ; Heat-Shock Proteins/analysis ; Heat-Shock Proteins/genetics ; Humans ; Infertility, Female/therapy ; Insulin Resistance/physiology ; Obesity/metabolism ; Ovary/chemistry ; Ovary/metabolism ; RNA, Messenger/analysis ; Serpins/genetics ; Serpins/pharmacology ; Steroids/biosynthesis
Czasopismo naukowe
Tytuł :
Ameliorative effects of fisetin in letrozole-induced rat model of polycystic ovary syndrome.
Autorzy :
Mihanfar A; Department of Clinical Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Nouri M; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran; Stem Cell and Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Roshangar L; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Khadem-Ansari MH; Department of Clinical Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran. Electronic address: .
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Źródło :
The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2021 Oct; Vol. 213, pp. 105954. Date of Electronic Publication: 2021 Jul 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Flavonols/*pharmacology
Letrozole/*antagonists & inhibitors
Ovary/*drug effects
Polycystic Ovary Syndrome/*drug therapy
AMP-Activated Protein Kinases/blood ; AMP-Activated Protein Kinases/genetics ; Animals ; Blood Glucose/metabolism ; Carboxymethylcellulose Sodium/administration & dosage ; Catalase/blood ; Catalase/genetics ; Disease Models, Animal ; Estradiol/blood ; Female ; Gene Expression ; Glutathione Peroxidase/blood ; Glutathione Peroxidase/genetics ; Humans ; Insulin/blood ; Letrozole/toxicity ; Metformin/pharmacology ; Ovary/metabolism ; Ovary/pathology ; Polycystic Ovary Syndrome/blood ; Polycystic Ovary Syndrome/chemically induced ; Polycystic Ovary Syndrome/pathology ; Progesterone/blood ; Rats ; Rats, Wistar ; Sirtuin 1/blood ; Sirtuin 1/genetics ; Steroid 17-alpha-Hydroxylase/antagonists & inhibitors ; Steroid 17-alpha-Hydroxylase/blood ; Steroid 17-alpha-Hydroxylase/genetics ; Superoxide Dismutase/blood ; Superoxide Dismutase/genetics ; Testosterone/blood
Czasopismo naukowe
Tytuł :
Beneficial effects of minocycline on the ovary of polycystic ovary syndrome mouse model: Molecular docking analysis and evaluation of TNF-α, TNFR2, TLR-4 gene expression.
Autorzy :
Khajouei A; Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran. Electronic address: .
Hosseini E; Department of Obstetrics and Gynecology, IVF Clinic, Mousavi Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran. Electronic address: .
Abdizadeh T; Clinical Biochemistry Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran. Electronic address: .
Kian M; Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran. Electronic address: .
Ghasemi S; Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran. Electronic address: .
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Źródło :
Journal of reproductive immunology [J Reprod Immunol] 2021 Apr; Vol. 144, pp. 103289. Date of Electronic Publication: 2021 Feb 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Minocycline/*pharmacology
Ovulation/*drug effects
Polycystic Ovary Syndrome/*drug therapy
Animals ; Disease Models, Animal ; Estradiol/administration & dosage ; Estradiol/toxicity ; Female ; Humans ; Letrozole/pharmacology ; Letrozole/therapeutic use ; Mice ; Minocycline/therapeutic use ; Molecular Docking Simulation ; Ovary/immunology ; Ovary/pathology ; Ovulation/immunology ; Polycystic Ovary Syndrome/chemically induced ; Polycystic Ovary Syndrome/immunology ; Polycystic Ovary Syndrome/pathology ; Receptors, Tumor Necrosis Factor, Type II/antagonists & inhibitors ; Receptors, Tumor Necrosis Factor, Type II/metabolism ; Signal Transduction/drug effects ; Signal Transduction/immunology ; Toll-Like Receptor 4/antagonists & inhibitors ; Toll-Like Receptor 4/metabolism ; Tumor Necrosis Factor-alpha/antagonists & inhibitors ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Upsurge in autophagy, associated with mifepristone-treated polycystic ovarian condition, is reversed upon thymoquinone treatment.
Autorzy :
Saha P; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India; Biochemistry and Toxicology Laboratory, School of Environmental Sciences, Jawaharlal Nehru University, New Delhi, 110067, India. Electronic address: .
Kumar S; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India.
Datta K; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India; Biochemistry and Toxicology Laboratory, School of Environmental Sciences, Jawaharlal Nehru University, New Delhi, 110067, India.
Tyagi RK; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India. Electronic address: .
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Źródło :
The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2021 Apr; Vol. 208, pp. 105823. Date of Electronic Publication: 2021 Jan 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autophagy/*drug effects
Benzoquinones/*pharmacology
Mifepristone/*pharmacology
Polycystic Ovary Syndrome/*drug therapy
Receptors, Androgen/*genetics
Androgens/metabolism ; Animals ; Autophagy/genetics ; Beclin-1/genetics ; Disease Models, Animal ; Female ; Gene Expression Regulation/drug effects ; Granulosa Cells/drug effects ; Humans ; Insulin Resistance/genetics ; Ovary/drug effects ; Ovary/growth & development ; Ovulation/drug effects ; Ovulation/genetics ; Polycystic Ovary Syndrome/genetics ; Polycystic Ovary Syndrome/pathology ; Rats ; eIF-2 Kinase/genetics
Czasopismo naukowe
Tytuł :
Polycystic ovary syndrome is an independent risk factor for hypertensive disorders of pregnancy: A systematic review, meta-analysis, and meta-regression.
Autorzy :
Pan H; Department of Traditional Chinese Medicine, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510240, China.
Xian P; Department of Traditional Chinese Medicine, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510240, China.
Yang D; Organ Transplant Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, 510240, China.
Zhang C; The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, NO.195 Dong Feng West Road, Guangzhou, 510240, PR China.
Tang H; Department of Traditional Chinese Medicine, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510240, China.
He X; Department of Traditional Chinese Medicine, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510240, China.
Lin H; Department of Traditional Chinese Medicine, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510240, China.
Wen X; The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, NO.195 Dong Feng West Road, Guangzhou, 510240, PR China.
Ma H; Department of Traditional Chinese Medicine, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510240, China. .
Lai M; Department of Traditional Chinese Medicine, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510240, China. .
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Źródło :
Endocrine [Endocrine] 2021 Dec; Vol. 74 (3), pp. 518-529. Date of Electronic Publication: 2021 Oct 16.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Diabetes, Gestational*/epidemiology
Hypertension, Pregnancy-Induced*/epidemiology
Hypertension, Pregnancy-Induced*/etiology
Polycystic Ovary Syndrome*/complications
Polycystic Ovary Syndrome*/epidemiology
Pre-Eclampsia*/epidemiology
Pre-Eclampsia*/etiology
Female ; Humans ; Pregnancy ; Risk Factors
Czasopismo naukowe
Tytuł :
Polycystic ovary syndrome: epidemiologic assessment of prevalence of systemic rheumatic and autoimmune diseases.
Autorzy :
Sharmeen S; Division of Rheumatology, Allergy and Immunology, Department of Medicine, Stony Brook University Renaissance School of Medicine, Stony Brook, NY, 11794, USA.
Nomani H; Division of Rheumatology, Allergy and Immunology, Department of Medicine, Stony Brook University Renaissance School of Medicine, Stony Brook, NY, 11794, USA.
Taub E; Division of Rheumatology, Allergy and Immunology, Department of Medicine, Stony Brook University Renaissance School of Medicine, Stony Brook, NY, 11794, USA.
Carlson H; Division of Endocrinology, Department of Medicine, Stony Brook University Renaissance School of Medicine, Stony Brook, NY, USA.
Yao Q; Division of Rheumatology, Allergy and Immunology, Department of Medicine, Stony Brook University Renaissance School of Medicine, Stony Brook, NY, 11794, USA. .
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Źródło :
Clinical rheumatology [Clin Rheumatol] 2021 Dec; Vol. 40 (12), pp. 4837-4843. Date of Electronic Publication: 2021 Jul 03.
Typ publikacji :
Journal Article
MeSH Terms :
Autoimmune Diseases*/complications
Autoimmune Diseases*/epidemiology
Hyperandrogenism*
Polycystic Ovary Syndrome*/complications
Polycystic Ovary Syndrome*/epidemiology
Adult ; Female ; Humans ; Prevalence ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Efficacy of Bushen Huatan Decoction combined with Baduanjin in the treatment of polycystic ovary syndrome with insulin resistance (IR-PCOS), kidney deficiency and phlegm dampness: study protocol for a randomized controlled trial.
Autorzy :
Qian H; Department of Reproduction, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China.
Xu W; Department of Reproduction, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China.
Cui L; Department of Pathology, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China.
Wang R; Department of Laboratory Medicine, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China.
Wang J; Department of Reproduction, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China.
Tang M; Department of Reproduction, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China.
Wei M; The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. .
Wang L; Department of Reproduction, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Suzhou, Jiangsu, China. .
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Źródło :
Trials [Trials] 2021 Nov 07; Vol. 22 (1), pp. 781. Date of Electronic Publication: 2021 Nov 07.
Typ publikacji :
Clinical Trial Protocol; Journal Article
MeSH Terms :
Insulin Resistance*
Metabolic Syndrome*
Metformin*
Polycystic Ovary Syndrome*/diagnosis
Polycystic Ovary Syndrome*/drug therapy
Female ; Humans ; Insulin ; Kidney ; Pregnancy ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł :
Temporal relationship between alterations in the gut microbiome and the development of polycystic ovary syndrome-like phenotypes in prenatally androgenized female mice.
Autorzy :
Kusamoto A; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Harada M; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Azhary JMK; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.; Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Kunitomi C; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Nose E; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Koike H; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Xu Z; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Urata Y; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Kaku T; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Takahashi N; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Wada-Hiraike O; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Hirota Y; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Koga K; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Fujii T; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Osuga Y; Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Nov; Vol. 35 (11), pp. e21971.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gastrointestinal Microbiome*
Polycystic Ovary Syndrome*/metabolism
Polycystic Ovary Syndrome*/microbiology
Androgens/*metabolism
Prenatal Exposure Delayed Effects/*microbiology
Animals ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Pregnancy
Czasopismo naukowe
Tytuł :
Risk of type 2 diabetes mellitus in polycystic ovary syndrome is associated with obesity: a meta-analysis of observational studies.
Autorzy :
Anagnostis P; Unit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece. .
Paparodis RD; Center for Diabetes and Endocrine Research, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Bosdou JK; Unit for Human Reproduction, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Bothou C; Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital Zurich (USZ) and University of Zurich (UZH), Zürich, Switzerland.
Macut D; Clinic for Endocrinology, Diabetes and Metabolic Diseases, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Goulis DG; Unit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Livadas S; Endocrine Unit, Metropolitan Hospital, Athens, Greece.
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Źródło :
Endocrine [Endocrine] 2021 Nov; Vol. 74 (2), pp. 245-253. Date of Electronic Publication: 2021 Jun 26.
Typ publikacji :
Journal Article; Meta-Analysis
MeSH Terms :
Diabetes Mellitus, Type 2*/epidemiology
Diabetes Mellitus, Type 2*/etiology
Polycystic Ovary Syndrome*/complications
Polycystic Ovary Syndrome*/epidemiology
Body Mass Index ; Female ; Humans ; Obesity/complications ; Obesity/epidemiology ; Overweight
Czasopismo naukowe
Tytuł :
Prevalence and Predictors of Impaired Glucose Tolerance and Diabetes Mellitus Type 2 in Patients with Polycystic Ovary Syndrome.
Autorzy :
Krstevska B; Internal Medicine Centre 'Srce', Skopje, N Macedonia.
Mishevska SJ; University Clinic of Endocrinology, Diabetes and Metabolic Disorders, Skopje, N Macedonia.
Nakova VV; Clinical Hospital, Shtip, N Macedonia.
Serafimoski V; Macedonian Academy of Science, Skopje, N Macedonia.
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Źródło :
Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki) [Pril (Makedon Akad Nauk Umet Odd Med Nauki)] 2021 Oct 26; Vol. 42 (2), pp. 61-70. Date of Electronic Publication: 2021 Oct 26.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2*/diagnosis
Diabetes Mellitus, Type 2*/epidemiology
Glucose Intolerance*/diagnosis
Glucose Intolerance*/epidemiology
Polycystic Ovary Syndrome*/diagnosis
Polycystic Ovary Syndrome*/epidemiology
Body Mass Index ; Cross-Sectional Studies ; Female ; Humans ; Prevalence
Czasopismo naukowe

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