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Wyszukujesz frazę ""Oxidative Stress"" wg kryterium: Temat


Tytuł:
TXNIP knockdown protects rats against bupivacaine-induced spinal neurotoxicity via the inhibition of oxidative stress and apoptosis.
Autorzy:
Zhao Y; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning, 530021, Guangxi, China; Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, No.1 Maoyuan South Road, Nanchong, 637000, Sichuan, China.
Chen Y; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning, 530021, Guangxi, China.
Liu Z; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning, 530021, Guangxi, China.
Zhou L; Department of Anesthesiology, Meishan People's Hospital, No. 288 South Fourth Section of Dongpo Avenue, 620020, Sichuan, China.
Huang J; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning, 530021, Guangxi, China.
Luo X; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning, 530021, Guangxi, China.
Luo Y; Department of Anesthesiology, Guizhou Provincial People's Hospital, Guiyang, 557300, Guizhou, China.
Li J; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning, 530021, Guangxi, China; Department of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Lin Y; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning, 530021, Guangxi, China.
Lai J; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning, 530021, Guangxi, China. Electronic address: .
Liu J; Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning, 530021, Guangxi, China. Electronic address: .
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Źródło:
Free radical biology & medicine [Free Radic Biol Med] 2024 Jul; Vol. 219, pp. 1-16. Date of Electronic Publication: 2024 Apr 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*/drug effects
Bupivacaine*/toxicity
Bupivacaine*/adverse effects
Carrier Proteins*/genetics
Carrier Proteins*/metabolism
Gene Knockdown Techniques*
Neurotoxicity Syndromes*/etiology
Neurotoxicity Syndromes*/genetics
Neurotoxicity Syndromes*/metabolism
Neurotoxicity Syndromes*/pathology
Oxidative Stress*/drug effects
Oxidative Stress*/genetics
RNA, Small Interfering*/genetics
Spinal Cord*/metabolism
Spinal Cord*/pathology
Spinal Cord*/drug effects
Animals ; Rats ; Cell Cycle Proteins/metabolism ; Cell Cycle Proteins/genetics ; Injections, Spinal ; Neurons/drug effects ; Neurons/pathology ; Neurons/metabolism ; PC12 Cells ; Rats, Sprague-Dawley ; Thioredoxins/genetics ; Thioredoxins/metabolism
Czasopismo naukowe
Tytuł:
The role of oxidative stress in intervertebral disc degeneration: Mechanisms and therapeutic implications.
Autorzy:
Chen X; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Zhang A; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Zhao K; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Gao H; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Shi P; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Chen Y; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Cheng Z; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Zhou W; Department of Operating Room, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address: .
Zhang Y; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address: .
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Źródło:
Ageing research reviews [Ageing Res Rev] 2024 Jul; Vol. 98, pp. 102323. Date of Electronic Publication: 2024 May 09.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Stress*/physiology
Oxidative Stress*/drug effects
Intervertebral Disc Degeneration*/metabolism
Intervertebral Disc Degeneration*/therapy
Intervertebral Disc Degeneration*/drug therapy
Antioxidants*/therapeutic use
Antioxidants*/pharmacology
Humans ; Animals ; Reactive Oxygen Species/metabolism ; Intervertebral Disc/metabolism ; Intervertebral Disc/drug effects
Czasopismo naukowe
Tytuł:
Ashwagandha Diminishes Hippocampal Apoptosis Induced by Microwave Radiation by Acetylcholinesterase Dependent Neuro-Inflammatory Pathway in Male Coturnix coturnix Japonica.
Autorzy:
Gupta V; Avian Reproductive and Endocrinology Laboratory, Department of Zoology, School of Biological Sciences, Dr. Harisingh Gour Central University, Sagar, MP, 470003, India.
Srivastava R; Department of Zoology, Faculty of Science, University of Allahabad, Prayagraj, UP, 211002, India. .
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Źródło:
Neurochemical research [Neurochem Res] 2024 Jul; Vol. 49 (7), pp. 1687-1702. Date of Electronic Publication: 2024 Mar 20.
Typ publikacji:
Journal Article
MeSH Terms:
Microwaves*
Hippocampus*/drug effects
Hippocampus*/metabolism
Hippocampus*/radiation effects
Apoptosis*/drug effects
Apoptosis*/radiation effects
Plant Extracts*/pharmacology
Plant Extracts*/therapeutic use
Coturnix*
Acetylcholinesterase*/metabolism
Oxidative Stress*/drug effects
Oxidative Stress*/radiation effects
Animals ; Male ; Neuroinflammatory Diseases/prevention & control ; Neuroinflammatory Diseases/metabolism ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use
Czasopismo naukowe
Tytuł:
Prolactin is an Endogenous Antioxidant Factor in Astrocytes That Limits Oxidative Stress-Induced Astrocytic Cell Death via the STAT3/NRF2 Signaling Pathway.
Autorzy:
Ulloa M; Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus UNAM-Juriquilla, 76230, Querétaro, México.; Posgrado en Ciencias Biológicas, Universidad Nacional Autónoma de México, Ciudad Universitaria, 04510, Mexico City, México.
Macías F; Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus UNAM-Juriquilla, 76230, Querétaro, México.
Clapp C; Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus UNAM-Juriquilla, 76230, Querétaro, México.
Martínez de la Escalera G; Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus UNAM-Juriquilla, 76230, Querétaro, México. .
Arnold E; Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus UNAM-Juriquilla, 76230, Querétaro, México. .; CONAHCYT-Universidad Nacional Autónoma de México, Campus UNAM-Juriquilla, Querétaro, México. .
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Źródło:
Neurochemical research [Neurochem Res] 2024 Jul; Vol. 49 (7), pp. 1879-1901. Date of Electronic Publication: 2024 May 17.
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes*/metabolism
Astrocytes*/drug effects
NF-E2-Related Factor 2*/metabolism
Oxidative Stress*/drug effects
Oxidative Stress*/physiology
STAT3 Transcription Factor*/metabolism
Signal Transduction*/drug effects
Signal Transduction*/physiology
Prolactin*/pharmacology
Prolactin*/metabolism
Antioxidants*/pharmacology
Cell Death*/drug effects
Cell Death*/physiology
Hydrogen Peroxide*/toxicity
Hydrogen Peroxide*/pharmacology
Animals ; Cells, Cultured ; Mice ; Rats
Czasopismo naukowe
Tytuł:
FOXA1 Suppresses Endoplasmic Reticulum Stress, Oxidative Stress, and Neuronal Apoptosis in Parkinson's Disease by Activating PON2 Transcription.
Autorzy:
Liu J; Department of Neurology, The Baotou Central Hospital, Baotou, 014040, Inner Mongolia, People's Republic of China.
Fan Y; Department of Neurology, The Baotou Central Hospital, Baotou, 014040, Inner Mongolia, People's Republic of China.
Chen J; Department of Neurology, The Baotou Central Hospital, Baotou, 014040, Inner Mongolia, People's Republic of China.
Zhao M; Department of Neurology, The Baotou Central Hospital, Baotou, 014040, Inner Mongolia, People's Republic of China.
Jiang C; Department of Neurology, The Baotou Central Hospital, Baotou, 014040, Inner Mongolia, People's Republic of China. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2024 Jun 27; Vol. 42 (4), pp. 31. Date of Electronic Publication: 2024 Jun 27.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/drug effects
Apoptosis*/physiology
Aryldialkylphosphatase*/metabolism
Aryldialkylphosphatase*/genetics
Endoplasmic Reticulum Chaperone BiP*
Endoplasmic Reticulum Stress*/physiology
Endoplasmic Reticulum Stress*/drug effects
Hepatocyte Nuclear Factor 3-alpha*/metabolism
Hepatocyte Nuclear Factor 3-alpha*/genetics
Mice, Inbred C57BL*
Oxidative Stress*/drug effects
Oxidative Stress*/physiology
Animals ; Humans ; Male ; Mice ; Cell Line, Tumor ; Neurons/metabolism ; Neurons/drug effects
Czasopismo naukowe
Tytuł:
V-set and immunoglobulin domain containing 4 inhibits oxidative stress, mitochondrial dysfunction, and inflammation to attenuate Parkinson's disease progression by activating the JAK2/STAT3 pathway.
Autorzy:
Cai P; Department of Neurology, Xiamen Humanity Hospital Fujian Medical University, Xiamen 361016, Fujian, China.
Wang J; Department of Neurology, Xiamen Humanity Hospital Fujian Medical University, Xiamen 361016, Fujian, China; Department of Neurology and Institute of Neurology, First Affiliated Hospital, Fujian Medical University, Fuzhou 350004, Fujian, China.
Xu J; Department of Neurology, Xiamen Humanity Hospital Fujian Medical University, Xiamen 361016, Fujian, China.
Zhang M; Department of Neurology, Xiamen Humanity Hospital Fujian Medical University, Xiamen 361016, Fujian, China.
Yin X; Department of Neurology, Xiamen Humanity Hospital Fujian Medical University, Xiamen 361016, Fujian, China.
He S; Department of Neurology, Xiamen Humanity Hospital Fujian Medical University, Xiamen 361016, Fujian, China.
Zhuang J; Department of Neurology, Zhongshan Hospital Xiamen University, Xiamen 361004, Fujian, China. Electronic address: .
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Źródło:
Journal of neuroimmunology [J Neuroimmunol] 2024 Jun 15; Vol. 391, pp. 578345. Date of Electronic Publication: 2024 Apr 17.
Typ publikacji:
Journal Article
MeSH Terms:
Disease Progression*
Janus Kinase 2*/metabolism
Oxidative Stress*/drug effects
Oxidative Stress*/physiology
Signal Transduction*/drug effects
Signal Transduction*/physiology
STAT3 Transcription Factor*/metabolism
Animals ; Mice ; Cell Line ; Inflammation/metabolism ; Mitochondria/drug effects ; Mitochondria/metabolism ; Parkinson Disease/metabolism ; Parkinson Disease/drug therapy ; Pyrazoles/pharmacology ; Pyrimidines/pharmacology
Czasopismo naukowe
Tytuł:
GIP attenuates neuronal oxidative stress by regulating glucose uptake in spinal cord injury of rat.
Autorzy:
Guo B; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Medical School, Nantong University, Nantong, China.
Qi M; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, Nantong, China.
Luo X; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, Nantong, China.
Guo L; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, Nantong, China.
Xu M; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, Nantong, China.
Zhang Y; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Medical School, Nantong University, Nantong, China.
Li Z; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, Nantong, China.
Li M; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, Nantong, China.
Wu R; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, Nantong, China.
Guan T; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, Nantong, China.
Liu M; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, Nantong, China.
Liu Y; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, Nantong, China.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Jun; Vol. 30 (6), pp. e14806.
Typ publikacji:
Journal Article
MeSH Terms:
Gastric Inhibitory Polypeptide*/pharmacology
Gastric Inhibitory Polypeptide*/metabolism
Glucose*/metabolism
Oxidative Stress*/drug effects
Oxidative Stress*/physiology
Spinal Cord Injuries*/metabolism
Spinal Cord Injuries*/drug therapy
Spinal Cord Injuries*/pathology
Neurons*/metabolism
Neurons*/drug effects
Rats, Sprague-Dawley*
Reactive Oxygen Species*/metabolism
Glucose Transporter Type 3*/metabolism
Animals ; Rats ; Apoptosis/drug effects ; Apoptosis/physiology ; Male ; Cells, Cultured ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism
Czasopismo naukowe
Tytuł:
Expression profile of viability and stress response genes as a result of resveratrol supplementation in vitrified and in vitro produced cattle embryos.
Autorzy:
Saber YHA; Department of Animal Reproduction and A.I, Veterinary Research Institute, National Research Centre, Dokki, Giza, Egypt. Yasserhussein_.
Ibrahim S; Department of Animal Reproduction and A.I, Veterinary Research Institute, National Research Centre, Dokki, Giza, Egypt.
Mahmoud KGM; Department of Animal Reproduction and A.I, Veterinary Research Institute, National Research Centre, Dokki, Giza, Egypt.
Ahmed WM; Department of Animal Reproduction and A.I, Veterinary Research Institute, National Research Centre, Dokki, Giza, Egypt.
Ragab RSA; Department of Theriogenology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Seida AAM; Department of Theriogenology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
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Źródło:
Molecular biology reports [Mol Biol Rep] 2024 May 25; Vol. 51 (1), pp. 692. Date of Electronic Publication: 2024 May 25.
Typ publikacji:
Journal Article
MeSH Terms:
Resveratrol*/pharmacology
Vitrification*/drug effects
Oxidative Stress*/drug effects
Oxidative Stress*/genetics
Cryopreservation*/methods
Antioxidants*/pharmacology
Antioxidants*/metabolism
Blastocyst*/drug effects
Blastocyst*/metabolism
Animals ; Cattle ; Gene Expression Regulation, Developmental/drug effects ; Fertilization in Vitro/veterinary ; Fertilization in Vitro/methods ; Embryo, Mammalian/drug effects ; Embryo, Mammalian/metabolism ; Embryo Culture Techniques/methods ; Embryonic Development/drug effects ; Embryonic Development/genetics ; Oocytes/drug effects ; Oocytes/metabolism ; Female
Czasopismo naukowe
Tytuł:
Hydrogen-rich solution alleviates acute radiation pneumonitis by regulating oxidative stress and macrophages polarization.
Autorzy:
Yin Z; Department of Oncology, Chongqing Traditional Chinese Medicine Hospital, 400021, Chongqing, China.
Xu W; Department of Oncology, Chongqing Traditional Chinese Medicine Hospital, 400021, Chongqing, China.
Ling J; Department of Oncology, Chongqing Traditional Chinese Medicine Hospital, 400021, Chongqing, China.
Ma L; Department of Oncology, Chongqing Traditional Chinese Medicine Hospital, 400021, Chongqing, China.
Zhang H; Department of Oncology, Chongqing Traditional Chinese Medicine Hospital, 400021, Chongqing, China.
Wang P; Department of Oncology, Chongqing Traditional Chinese Medicine Hospital, 400021, Chongqing, China.
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Źródło:
Journal of radiation research [J Radiat Res] 2024 May 23; Vol. 65 (3), pp. 291-302.
Typ publikacji:
Journal Article
MeSH Terms:
Oxidative Stress*/drug effects
Oxidative Stress*/radiation effects
Hydrogen*/pharmacology
Hydrogen*/therapeutic use
Autophagy*/drug effects
Autophagy*/radiation effects
Macrophages*/drug effects
Macrophages*/metabolism
Macrophages*/radiation effects
Radiation Pneumonitis*/drug therapy
Radiation Pneumonitis*/pathology
Radiation Pneumonitis*/metabolism
Rats, Sprague-Dawley*
Animals ; Male ; Rats ; Signal Transduction/drug effects ; TOR Serine-Threonine Kinases/metabolism ; AMP-Activated Protein Kinases/metabolism ; Autophagy-Related Protein-1 Homolog/metabolism ; Cell Polarity/drug effects ; Cell Polarity/radiation effects ; Mitochondria/metabolism ; Mitochondria/drug effects ; Mitochondria/radiation effects ; Acute Disease
Czasopismo naukowe
Tytuł:
Nuclear Factor Erythroid 2-Related Factor 2 as a Potential Therapeutic Target in Neonatal Hypoxic-Ischemic Encephalopathy.
Autorzy:
Liu JX; Key Laboratory of Cognitive Science, Laboratory of Membrane Ion Channels and Medicine, College of Biomedical Engineering, South-Central Minzu University, 430079 Wuhan, Hubei, China.
Zheng D; Key Laboratory of Cognitive Science, Laboratory of Membrane Ion Channels and Medicine, College of Biomedical Engineering, South-Central Minzu University, 430079 Wuhan, Hubei, China.
Chen L; Key Laboratory of Cognitive Science, Laboratory of Membrane Ion Channels and Medicine, College of Biomedical Engineering, South-Central Minzu University, 430079 Wuhan, Hubei, China.
Chen S; Key Laboratory of Cognitive Science, Laboratory of Membrane Ion Channels and Medicine, College of Biomedical Engineering, South-Central Minzu University, 430079 Wuhan, Hubei, China.
Min JW; Key Laboratory of Cognitive Science, Laboratory of Membrane Ion Channels and Medicine, College of Biomedical Engineering, South-Central Minzu University, 430079 Wuhan, Hubei, China.
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Źródło:
Journal of integrative neuroscience [J Integr Neurosci] 2024 May 16; Vol. 23 (5), pp. 103.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Hypoxia-Ischemia, Brain*/metabolism
Hypoxia-Ischemia, Brain*/drug therapy
NF-E2-Related Factor 2*/metabolism
Oxidative Stress*/drug effects
Oxidative Stress*/physiology
Humans ; Infant, Newborn ; Animals ; Antioxidants/pharmacology ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł:
Excessive intragastric alcohol administration exacerbates hepatic encephalopathy and provokes neuronal cell death in male rats with chronic liver disease.
Autorzy:
Tamnanloo F; Hepato-Neuro Lab, CRCHUM, Montréal, Québec, Canada.; Medicine Department, Université de Montréal, Montréal, Québec, Canada.
Chen X; Hepato-Neuro Lab, CRCHUM, Montréal, Québec, Canada.
Oliveira MM; Hepato-Neuro Lab, CRCHUM, Montréal, Québec, Canada.
Tremblay M; Hepato-Neuro Lab, CRCHUM, Montréal, Québec, Canada.
Rose CF; Hepato-Neuro Lab, CRCHUM, Montréal, Québec, Canada.; Medicine Department, Université de Montréal, Montréal, Québec, Canada.
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Źródło:
Journal of neuroscience research [J Neurosci Res] 2024 May; Vol. 102 (5), pp. e25337.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Hepatic Encephalopathy*/pathology
Hepatic Encephalopathy*/chemically induced
Hepatic Encephalopathy*/metabolism
Ethanol*/toxicity
Ethanol*/adverse effects
Neurons*/pathology
Neurons*/drug effects
Neurons*/metabolism
Oxidative Stress*/drug effects
Oxidative Stress*/physiology
Animals ; Male ; Rats ; Cell Death/drug effects ; Rats, Sprague-Dawley ; Apoptosis/drug effects ; Anxiety/etiology
Czasopismo naukowe
Tytuł:
Gastrodin ameliorates synaptic impairment, mitochondrial dysfunction and oxidative stress in N2a/APP cells.
Autorzy:
Tang Z; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education and Key Laboratory of Medical Molecular Biology of Guizhou Province, Guizhou Medical University, Guiyang, China; Basic Medical College, Guizhou Medical University, Guiyang, China.
Peng Y; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education and Key Laboratory of Medical Molecular Biology of Guizhou Province, Guizhou Medical University, Guiyang, China; Basic Medical College, Guizhou Medical University, Guiyang, China.
Jiang Y; Department of Pathology, Affiliated Hospital of Traditional Chinese Medicine of Guangzhou Medical University, Guangzhou, China.
Wang L; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education and Key Laboratory of Medical Molecular Biology of Guizhou Province, Guizhou Medical University, Guiyang, China; Basic Medical College, Guizhou Medical University, Guiyang, China.
Guo M; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education and Key Laboratory of Medical Molecular Biology of Guizhou Province, Guizhou Medical University, Guiyang, China; Basic Medical College, Guizhou Medical University, Guiyang, China.
Chen Z; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education and Key Laboratory of Medical Molecular Biology of Guizhou Province, Guizhou Medical University, Guiyang, China; Basic Medical College, Guizhou Medical University, Guiyang, China.
Luo C; Basic Medical College, Guizhou Medical University, Guiyang, China.
Zhang T; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education and Key Laboratory of Medical Molecular Biology of Guizhou Province, Guizhou Medical University, Guiyang, China; Basic Medical College, Guizhou Medical University, Guiyang, China.
Xiao Y; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education and Key Laboratory of Medical Molecular Biology of Guizhou Province, Guizhou Medical University, Guiyang, China; Basic Medical College, Guizhou Medical University, Guiyang, China.
Ni R; Institute for Regenerative Medicine, University of Zurich, Zurich, Switzerland; Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Zurich, Switzerland. Electronic address: .
Qi X; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education and Key Laboratory of Medical Molecular Biology of Guizhou Province, Guizhou Medical University, Guiyang, China; Basic Medical College, Guizhou Medical University, Guiyang, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Jul 30; Vol. 719, pp. 150127. Date of Electronic Publication: 2024 May 15.
Typ publikacji:
Journal Article
MeSH Terms:
Glucosides*/pharmacology
Benzyl Alcohols*/pharmacology
Oxidative Stress*/drug effects
Mitochondria*/drug effects
Mitochondria*/metabolism
Neuroprotective Agents*/pharmacology
Reactive Oxygen Species*/metabolism
Synapses*/drug effects
Synapses*/metabolism
Animals ; Mice ; Cell Line, Tumor ; Amyloid beta-Peptides/metabolism ; Amyloid beta-Protein Precursor/metabolism ; Amyloid beta-Protein Precursor/genetics ; Humans ; Alzheimer Disease/metabolism ; Alzheimer Disease/drug therapy ; Alzheimer Disease/pathology ; tau Proteins/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Peptide Fragments
Czasopismo naukowe
Tytuł:
Natural products for the treatment of age-related macular degeneration.
Autorzy:
Wang D; Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.
Chen Y; Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.
Li J; Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China; Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, PR China.
Wu E; Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, PR China.
Tang T; Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, PR China.
Singla RK; Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, PR China; School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab-144411, India. Electronic address: .
Shen B; Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, PR China. Electronic address: .
Zhang M; Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155522. Date of Electronic Publication: 2024 Mar 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Macular Degeneration*/drug therapy
Biological Products*/pharmacology
Biological Products*/therapeutic use
Oxidative Stress*/drug effects
Humans ; Animals ; Phytotherapy ; Vitamin A ; Retina/drug effects ; Phenols/pharmacology ; Phenols/therapeutic use ; Functional Food
Czasopismo naukowe
Tytuł:
Ginseng total saponin improves red blood cell oxidative stress injury by regulating tyrosine phosphorylation and glycolysis in red blood cells.
Autorzy:
Zhao Y; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Cui Y; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Ni W; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Yu S; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Pan D; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Liu S; Academic Affairs Office, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Jia Z; School of Pharmacy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Gao Y; School of Pharmacy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Zhao D; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Liu M; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China. Electronic address: .
Wang S; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155785. Date of Electronic Publication: 2024 May 28.
Typ publikacji:
Journal Article
MeSH Terms:
Oxidative Stress*/drug effects
Panax*/chemistry
Erythrocytes*/drug effects
Erythrocytes*/metabolism
Saponins*/pharmacology
Glycolysis*/drug effects
Hydrogen Peroxide*
Tyrosine*/analogs & derivatives
Tyrosine*/pharmacology
Tyrosine*/metabolism
Rats, Sprague-Dawley*
Animals ; Male ; Phosphorylation/drug effects ; Rats ; Hemolysis/drug effects ; Antioxidants/pharmacology ; Anion Exchange Protein 1, Erythrocyte/metabolism ; Apoptosis/drug effects
Czasopismo naukowe
Tytuł:
Costunolide ameliorates MNNG-induced chronic atrophic gastritis through inhibiting oxidative stress and DNA damage via activation of Nrf2.
Autorzy:
Wang R; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, 110016, China.
Zhao Y; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, 110016, China.
Zhou L; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, 110016, China.
Lin F; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, 110016, China.
Wan M; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, 110016, China.
Gan A; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, 110016, China.
Wu B; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, 110016, China.
Yan T; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, 110016, China. Electronic address: .
Jia Y; School of Functional Food and Wine, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, Liaoning Province, 110016, China. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155581. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Oxidative Stress*/drug effects
NF-E2-Related Factor 2*/metabolism
DNA Damage*/drug effects
Methylnitronitrosoguanidine*
Gastritis, Atrophic*/drug therapy
Gastritis, Atrophic*/chemically induced
Apoptosis*/drug effects
Gastric Mucosa*/drug effects
Gastric Mucosa*/pathology
Animals ; Male ; Rats ; Humans ; Rats, Sprague-Dawley ; Lactones/pharmacology ; Cell Line ; Antioxidants/pharmacology ; Disease Models, Animal ; Molecular Docking Simulation ; Sesquiterpenes
Czasopismo naukowe
Tytuł:
Melatonin mitigated methotrexate-induced hepatotoxicity through interrelated biological processes.
Autorzy:
Abdallah N; Department of Zoology, Faculty of Science, Mansoura University, Mansoura, Egypt.
Amer ME; Department of Zoology, Faculty of Science, Mansoura University, Mansoura, Egypt.
Amer MA; Department of Zoology, Faculty of Science, Mansoura University, Mansoura, Egypt.
El-Missiry MA; Department of Zoology, Faculty of Science, Mansoura University, Mansoura, Egypt.
Othman AI; Department of Zoology, Faculty of Science, Mansoura University, Mansoura, Egypt. .
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Źródło:
Molecular biology reports [Mol Biol Rep] 2024 Jul 22; Vol. 51 (1), pp. 833. Date of Electronic Publication: 2024 Jul 22.
Typ publikacji:
Journal Article
MeSH Terms:
Methotrexate*/adverse effects
Methotrexate*/toxicity
Melatonin*/pharmacology
Chemical and Drug Induced Liver Injury*/metabolism
Chemical and Drug Induced Liver Injury*/drug therapy
Oxidative Stress*/drug effects
Liver*/drug effects
Liver*/metabolism
Liver*/pathology
Antioxidants*/pharmacology
Antioxidants*/metabolism
Apoptosis*/drug effects
Hepatocytes*/drug effects
Hepatocytes*/metabolism
Animals ; Rats ; Male ; Superoxide Dismutase/metabolism ; Glutathione/metabolism ; Catalase/metabolism
Czasopismo naukowe
Tytuł:
Oxidative stress and type 2 diabetes: the development and the pathogenesis, Jordanian cross-sectional study.
Autorzy:
Abu Khadra KM; Department of Biological Sciences, Yarmouk University, Irbid, 21163, Jordan. .
Bataineh MI; Department of Biological Sciences, Yarmouk University, Irbid, 21163, Jordan.
Khalil A; Department of Biological Sciences, Yarmouk University, Irbid, 21163, Jordan.
Saleh J; Biochemistry Department, College of Medicine and Health Sciences, Sultan Qaboos University, 123, Muscat, Oman.
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Źródło:
European journal of medical research [Eur J Med Res] 2024 Jul 17; Vol. 29 (1), pp. 370. Date of Electronic Publication: 2024 Jul 17.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/metabolism
Diabetes Mellitus, Type 2*/blood
Oxidative Stress*
Humans ; Jordan/epidemiology ; Cross-Sectional Studies ; Male ; Female ; Middle Aged ; Malondialdehyde/blood ; Obesity/metabolism ; Obesity/blood ; Adult ; Catalase/blood ; Antioxidants/metabolism ; Reactive Oxygen Species/metabolism ; Reactive Oxygen Species/blood ; Uric Acid/blood
Czasopismo naukowe
Tytuł:
The protective effect of parthenolide in an in vitro model of Parkinson's disease through its regulation of nuclear factor-kappa B and oxidative stress.
Autorzy:
Shariat Razavi SA; Neurosurgery Department, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Vafaei F; Department of Pharmacy, Shahreza Branch, Islamic Azad University, Shahreza, Isfahan, PO 311-86145, Iran.
Ebrahimi SM; Department of Biochemistry, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
Abbasinezhad-Moud F; Department of Medical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Shahini A; Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Qoorchi Moheb Seraj F; Endovascular Section, Neurosurgical Department, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Alavi MS; Department of Pharmacology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Fadavieslam A; Department of Medical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ferns GA; Division of Medical Education, Brighton & Sussex Medical School, Falmer, Brighton, Sussex, BN1 9PH, UK.
Bahrami A; Clinical Research Development Unit, Faculty of Medicine, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. .; Clinical Research Development Unit of Akbar Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. .
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Źródło:
Molecular biology reports [Mol Biol Rep] 2024 Jul 17; Vol. 51 (1), pp. 819. Date of Electronic Publication: 2024 Jul 17.
Typ publikacji:
Journal Article
MeSH Terms:
Oxidative Stress*/drug effects
Sesquiterpenes*/pharmacology
NF-kappa B*/metabolism
Parkinson Disease*/metabolism
Parkinson Disease*/drug therapy
Reactive Oxygen Species*/metabolism
Cell Survival*/drug effects
Apoptosis*/drug effects
Oxidopamine*/pharmacology
Humans ; Cell Line, Tumor ; Neuroprotective Agents/pharmacology ; Antioxidants/pharmacology
Czasopismo naukowe
Tytuł:
Harnessing the Therapeutic Potential of Peptides for Synergistic Treatment of Alzheimer's Disease by Targeting Aβ Aggregation, Metal-Mediated Aβ Aggregation, Cholinesterase, Tau Degradation, and Oxidative Stress.
Autorzy:
Singh K; Department of Chemistry, Faculty of Basic and Applied Sciences, Sri Guru Granth Sahib World University, Fatehgarh Sahib, 140406 Punjab, India.
Kaur A; Department of Chemistry, Faculty of Basic and Applied Sciences, Sri Guru Granth Sahib World University, Fatehgarh Sahib, 140406 Punjab, India.
Goyal B; Department of Chemistry and Biochemistry, Thapar Institute of Engineering & Technology, Patiala, 147004 Punjab, India.
Goyal D; Department of Chemistry, DAV College, Sector 10, Chandigarh 160011, India.
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Źródło:
ACS chemical neuroscience [ACS Chem Neurosci] 2024 Jul 17; Vol. 15 (14), pp. 2545-2564. Date of Electronic Publication: 2024 Jul 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Alzheimer Disease*/drug therapy
Alzheimer Disease*/metabolism
Amyloid beta-Peptides*/metabolism
Oxidative Stress*/drug effects
tau Proteins*/metabolism
Animals ; Humans ; Cholinesterases/metabolism ; Peptides/pharmacology ; Peptides/therapeutic use ; Protein Aggregates/drug effects ; Protein Aggregates/physiology ; Protein Aggregation, Pathological/drug therapy ; Protein Aggregation, Pathological/metabolism
Czasopismo naukowe
Tytuł:
Associations between the oxidative balance score and constipation: a cross-sectional study of the NHANES, 2005-2010.
Autorzy:
Wang Y; Department of Pediatric Surgery, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Li J; Department of Pediatric Surgery, Tianjin Medical University General Hospital, Tianjin, 300052, China.; Department of General Surgery, Tianjin Haihe Hospital, Tianjin, 300350, China.
Sun W; Department of Pediatric Surgery, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Tong Y; Department of Pediatric Surgery, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Han L; Department of Pediatric Surgery, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Jiang Z; Department of Pediatric Surgery, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Xu W; Department of Pediatric Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, China. .
Sun D; Department of Pediatric Surgery, Tianjin Medical University General Hospital, Tianjin, 300052, China. .
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Źródło:
BMC public health [BMC Public Health] 2024 Jul 16; Vol. 24 (1), pp. 1908. Date of Electronic Publication: 2024 Jul 16.
Typ publikacji:
Journal Article
MeSH Terms:
Constipation*/epidemiology
Nutrition Surveys*
Oxidative Stress*/physiology
Humans ; Cross-Sectional Studies ; Female ; Male ; Middle Aged ; Adult ; Diet ; Life Style ; Aged ; Surveys and Questionnaires ; United States/epidemiology ; Logistic Models
Czasopismo naukowe

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