Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""P-Selectin"" wg kryterium: Temat


Tytuł :
Tandem P-selectin glycoprotein ligand immunoglobulin prevents lung vaso-occlusion in sickle cell disease mice.
Autorzy :
Vats R; Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA.
Tutuncuoglu E; Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA.
Pradhan-Sundd T; Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA; Sickle Cell Center of Excellence, University of Pittsburgh, Pittsburgh, PA; Division of Hematology and Oncology, University of Pittsburgh, Pittsburgh, PA.
Tejero J; Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA; Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA.
Shaw GD; Quell Pharma Inc., Plymouth, MA.
Sundd P; Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA; Sickle Cell Center of Excellence, University of Pittsburgh, Pittsburgh, PA; Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA. Electronic address: .
Pokaż więcej
Źródło :
Experimental hematology [Exp Hematol] 2020 Apr; Vol. 84, pp. 1-6.e1. Date of Electronic Publication: 2020 Mar 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anemia, Sickle Cell/*drug therapy
Immunoglobulins/*pharmacology
Lung Diseases/*drug therapy
P-Selectin/*pharmacology
Recombinant Fusion Proteins/*pharmacology
Vascular Diseases/*drug therapy
Anemia, Sickle Cell/genetics ; Anemia, Sickle Cell/metabolism ; Anemia, Sickle Cell/pathology ; Animals ; Female ; Humans ; Immunoglobulins/genetics ; Lung Diseases/genetics ; Lung Diseases/metabolism ; Lung Diseases/pathology ; Male ; Mice ; P-Selectin/genetics ; Rats ; Recombinant Fusion Proteins/genetics ; Vascular Diseases/genetics ; Vascular Diseases/metabolism
Czasopismo naukowe
Tytuł :
Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes.
Autorzy :
Han P; Department of Chemical and Environmental Engineering, School of Engineering and Applied Science, Yale University, New Haven, CT 06511, USA.
Hanlon D; Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
Arshad N; Department of Immunobiology, School of Medicine, Yale University, New Haven, CT 06511, USA.
Lee JS; Department of Biomedical Engineering, School of Engineering and Applied Science, Yale University, New Haven, CT 06511, USA.
Tatsuno K; Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
Robinson E; Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
Filler R; Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
Sobolev O; Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
Cote C; Yale Flow Cytometry Facility, School of Medicine, Yale University, New Haven, CT 06511, USA.
Rivera-Molina F; Yale CINEMA Lab, School of Medicine, Yale University, New Haven, CT 06511, USA.
Toomre D; Yale CINEMA Lab, School of Medicine, Yale University, New Haven, CT 06511, USA.
Fahmy T; Department of Chemical and Environmental Engineering, School of Engineering and Applied Science, Yale University, New Haven, CT 06511, USA.; Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.; Department of Immunobiology, School of Medicine, Yale University, New Haven, CT 06511, USA.; Department of Biomedical Engineering, School of Engineering and Applied Science, Yale University, New Haven, CT 06511, USA.
Edelson R; Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06511, USA.
Pokaż więcej
Źródło :
Science advances [Sci Adv] 2020 Mar 11; Vol. 6 (11), pp. eaaz1580. Date of Electronic Publication: 2020 Mar 11 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Antigen Presentation*
Blood Platelets/*immunology
Calcium Signaling/*immunology
Cell Differentiation/*immunology
Dendritic Cells/*immunology
Monocytes/*immunology
P-Selectin/*immunology
Animals ; Antigens, Neoplasm/genetics ; Antigens, Neoplasm/immunology ; Calcium Signaling/genetics ; Cell Differentiation/genetics ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/immunology ; Mice ; Mice, Transgenic ; NF-kappa B/genetics ; NF-kappa B/immunology ; P-Selectin/genetics ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
Carbon nano-onion-mediated dual targeting of P-selectin and P-glycoprotein to overcome cancer drug resistance.
Autorzy :
Wang H; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA. .; CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, 100190, Beijing, China. .; University of Chinese Academy of Sciences, 100049, Beijing, China. .
Liang Y; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
Yin Y; CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, 100190, Beijing, China.
Zhang J; CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, 100190, Beijing, China.
Su W; CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, 100190, Beijing, China.
White AM; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
Bin Jiang; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
Xu J; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
Zhang Y; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
Stewart S; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
Lu X; Department of Medical and Molecular Genetics and Melvin and Bren Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
He X; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA. .; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD, 21201, USA. .; Robert E. Fischell Institute for Biomedical Devices, University of Maryland, College Park, MD, 20742, USA. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2021 Jan 12; Vol. 12 (1), pp. 312. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Drug Delivery Systems*
Drug Resistance, Neoplasm*/drug effects
ATP Binding Cassette Transporter, Subfamily B, Member 1/*metabolism
Carbon/*chemistry
Nanoparticles/*chemistry
Neoplasms/*drug therapy
P-Selectin/*metabolism
Animals ; Cell Death/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Doxorubicin/pharmacology ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Mice ; Microfluidics ; Nanoparticles/ultrastructure ; Neoplasms/blood supply ; Photothermal Therapy ; Polysaccharides/chemistry ; Silicon Dioxide/chemistry
Czasopismo naukowe
Tytuł :
SARS-CoV-2 infection is associated with a pro-thrombotic platelet phenotype.
Autorzy :
Bongiovanni D; Department of Internal Medicine I, School of Medicine, University hospital rechts der Isar, Technical University of Munich, Munich, Germany. .; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany. .; Department of Cardiovascular Medicine, Humanitas Clinical and Research Center IRCCS and Humanitas University, Rozzano, Milan, Italy. .
Klug M; Department of Internal Medicine I, School of Medicine, University hospital rechts der Isar, Technical University of Munich, Munich, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.
Lazareva O; Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.
Weidlich S; Department of Internal Medicine II, School of Medicine, University hospital rechts der Isar, Technical University of Munich, Munich, Germany.
Biasi M; Department of Internal Medicine I, School of Medicine, University hospital rechts der Isar, Technical University of Munich, Munich, Germany.
Ursu S; Core Facility Cytometry, Ulm University Medical Faculty, Ulm, Germany.
Warth S; Core Facility Cytometry, Ulm University Medical Faculty, Ulm, Germany.
Buske C; Core Facility Cytometry, Ulm University Medical Faculty, Ulm, Germany.; CCC Ulm, Institute of Experimental Cancer Research, University Hospital Ulm, Ulm, Germany.
Lukas M; Department of Internal Medicine II, School of Medicine, University hospital rechts der Isar, Technical University of Munich, Munich, Germany.
Spinner CD; Department of Internal Medicine II, School of Medicine, University hospital rechts der Isar, Technical University of Munich, Munich, Germany.
Scheidt MV; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; Deutsches Herzzentrum München, Cardiology, Technical University of Munich, Munich, Germany.
Condorelli G; Department of Cardiovascular Medicine, Humanitas Clinical and Research Center IRCCS and Humanitas University, Rozzano, Milan, Italy.
Baumbach J; Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.
Laugwitz KL; Department of Internal Medicine I, School of Medicine, University hospital rechts der Isar, Technical University of Munich, Munich, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.
List M; Experimental Bioinformatics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.
Bernlochner I; Department of Internal Medicine I, School of Medicine, University hospital rechts der Isar, Technical University of Munich, Munich, Germany. .; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany. .
Pokaż więcej
Źródło :
Cell death & disease [Cell Death Dis] 2021 Jan 05; Vol. 12 (1), pp. 50. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Platelets/*pathology
COVID-19/*complications
Leukocytes/*pathology
SARS-CoV-2/*isolation & purification
Thrombosis/*epidemiology
Adult ; Blood Platelets/metabolism ; Blood Platelets/virology ; COVID-19/transmission ; COVID-19/virology ; Case-Control Studies ; Female ; Germany/epidemiology ; Humans ; Leukocytes/metabolism ; Leukocytes/virology ; Male ; Middle Aged ; P-Selectin/metabolism ; Peptide Fragments/metabolism ; Phenotype ; Platelet Glycoprotein GPIIb-IIIa Complex/metabolism ; Thrombosis/virology
Czasopismo naukowe
Tytuł :
Endothelial Function in Patients With Von Willebrand Disease.
Autorzy :
Noone S; Haemostaseology, Department of Internal Medicine II, Institute of Transfusion Medicine, University Hospital, Goethe University Frankfurt am Main, Frankfurt, Germany.
Schubert R; Department for Children and Adolescents Medicine, University Hospital Frankfurt, Frankfurt am Main, Germany.
Fichtlscherer S; Division of Cardiology, Department of Internal Medicine III, University Hospital Frankfurt, Frankfurt am Main, Germany.
Hilberg T; Department of Sports Medicine, University of Wuppertal, Wuppertal, Germany.
Alesci S; IMD Blood Coagulation Centre, Bad Homburg, Germany.
Miesbach W; Haemostaseology, Department of Internal Medicine II, Institute of Transfusion Medicine, University Hospital, Goethe University Frankfurt am Main, Frankfurt, Germany.
Pokaż więcej
Źródło :
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis [Clin Appl Thromb Hemost] 2021 Jan-Dec; Vol. 27, pp. 1076029620984546.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelium, Vascular/*physiopathology
von Willebrand Diseases/*physiopathology
Adult ; Biomarkers/blood ; Case-Control Studies ; Chemokine CCL2/blood ; Coronary Artery Disease/blood ; Coronary Artery Disease/physiopathology ; Female ; Humans ; Hyperemia/blood ; Hyperemia/physiopathology ; Intercellular Adhesion Molecule-1/blood ; Interleukin-6/blood ; Male ; Middle Aged ; P-Selectin/blood ; von Willebrand Disease, Type 1/blood ; von Willebrand Disease, Type 1/physiopathology ; von Willebrand Disease, Type 2/blood ; von Willebrand Disease, Type 2/physiopathology ; von Willebrand Disease, Type 3/blood ; von Willebrand Disease, Type 3/physiopathology ; von Willebrand Diseases/blood
Czasopismo naukowe
Tytuł :
Prediction of survival odds in COVID-19 by zinc, age and selenoprotein P as composite biomarker.
Autorzy :
Heller RA; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, And Berlin Institute of Health, D-13353, Berlin, Germany; HTRG, Heidelberg Trauma Research Group, Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Heidelberg University Hospital, D-69118, Heidelberg, Germany; Department of General Practice and Health Services Research, University Hospital Heidelberg, D-69120, Heidelberg, Germany. Electronic address: .
Sun Q; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, And Berlin Institute of Health, D-13353, Berlin, Germany. Electronic address: .
Hackler J; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, And Berlin Institute of Health, D-13353, Berlin, Germany. Electronic address: .
Seelig J; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, And Berlin Institute of Health, D-13353, Berlin, Germany. Electronic address: .
Seibert L; ATORG, Aschaffenburg Trauma and Orthopedic Research Group, Center for Orthopedics, Trauma Surgery and Sports Medicine, Hospital Aschaffenburg-Alzenau, D-63739, Aschaffenburg, Germany. Electronic address: .
Cherkezov A; ATORG, Aschaffenburg Trauma and Orthopedic Research Group, Center for Orthopedics, Trauma Surgery and Sports Medicine, Hospital Aschaffenburg-Alzenau, D-63739, Aschaffenburg, Germany. Electronic address: .
Minich WB; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, And Berlin Institute of Health, D-13353, Berlin, Germany. Electronic address: .
Seemann P; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, And Berlin Institute of Health, D-13353, Berlin, Germany. Electronic address: .
Diegmann J; ATORG, Aschaffenburg Trauma and Orthopedic Research Group, Center for Orthopedics, Trauma Surgery and Sports Medicine, Hospital Aschaffenburg-Alzenau, D-63739, Aschaffenburg, Germany. Electronic address: .
Pilz M; Institute of Medical Biometry and Informatics, Heidelberg University Hospital, Im Neuenheimer Feld 130.3, D-69120, Heidelberg, Germany. Electronic address: .
Bachmann M; ATORG, Aschaffenburg Trauma and Orthopedic Research Group, Center for Orthopedics, Trauma Surgery and Sports Medicine, Hospital Aschaffenburg-Alzenau, D-63739, Aschaffenburg, Germany. Electronic address: .
Ranjbar A; Department of Allergy and Immunology, Mashhad University of Medical Sciences, Mashhad, Iran; Institute of Interventional Allergology und Immunology, Bonn, Cologne, Germany. Electronic address: .
Moghaddam A; ATORG, Aschaffenburg Trauma and Orthopedic Research Group, Center for Orthopedics, Trauma Surgery and Sports Medicine, Hospital Aschaffenburg-Alzenau, D-63739, Aschaffenburg, Germany.
Schomburg L; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, And Berlin Institute of Health, D-13353, Berlin, Germany. Electronic address: .
Pokaż więcej
Źródło :
Redox biology [Redox Biol] 2021 Jan; Vol. 38, pp. 101764. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*blood
COVID-19/*mortality
P-Selectin/*blood
SARS-CoV-2/*metabolism
Zinc/*blood
Adult ; Age Factors ; Aged ; Aged, 80 and over ; COVID-19/diagnosis ; Cross-Sectional Studies ; Disease-Free Survival ; Female ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Survival Rate
Czasopismo naukowe
Tytuł :
Analysis of Serum Markers with Regard to Treatment Procedures in Advanced Stage Prostate Cancer Patients.
Autorzy :
Wolny-Rokicka E; Department of Radiotherapy, Multidisciplinary Hospital in Gorzów Wielkopolski, Gorzów Wielkopolski, Poland.
Petrasz P; Department of Urology, Multidisciplinary Hospital in Gorzów Wielkopolski, Gorzów Wielkopolski, Poland.
Krajewski W; Department of Urology and Oncologic Urology, Wrocław Medical University, Wrocław, Poland.
Sulimiera Michalak S; Primary Medical Care Clinic 'Skarbowa', Zielona Góra, Poland.
Tukiendorf A; Social Medicine Department, Medical University in Wrocław, Wrocław, Poland.
Pokaż więcej
Źródło :
Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2020 Dec 16; Vol. 26, pp. e925860. Date of Electronic Publication: 2020 Dec 16.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Neoplasm Recurrence, Local*/blood
Neoplasm Recurrence, Local*/diagnosis
Prostatic Neoplasms*/blood
Prostatic Neoplasms*/pathology
Prostatic Neoplasms*/surgery
Cell-Free Nucleic Acids/*blood
P-Selectin/*blood
Receptors, Tumor Necrosis Factor, Type I/*blood
Receptors, Tumor Necrosis Factor, Type II/*blood
Aged ; Apoptosis ; Biomarkers/blood ; Humans ; Male ; Neoplasm Staging ; Prognosis ; Prostatectomy/adverse effects ; Prostatectomy/methods ; Prostatectomy/statistics & numerical data ; Risk Assessment/methods
Czasopismo naukowe
Tytuł :
An in vitro model to mimic the thrombotic occlusion of small vessels in catastrophic antiphospholipid syndrome (CAPS).
Autorzy :
Pontara E; Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Cheng C; Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Cattini MG; Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Bison E; Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Pelloso M; Department of Medicine, Padova University Hospital, Padova, Italy.
Denas G; Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Pengo V; Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Pokaż więcej
Źródło :
Lupus [Lupus] 2019 Dec; Vol. 28 (14), pp. 1663-1668. Date of Electronic Publication: 2019 Nov 08.
Typ publikacji :
Journal Article
MeSH Terms :
Platelet Activation*
Antiphospholipid Syndrome/*blood
Autoantibodies/*pharmacology
P-Selectin/*metabolism
Thrombosis/*etiology
beta 2-Glycoprotein I/*immunology
Adult ; Antibodies, Anticardiolipin/blood ; Antiphospholipid Syndrome/complications ; Antiphospholipid Syndrome/immunology ; Autoantibodies/blood ; Enzyme-Linked Immunosorbent Assay ; Female ; Flow Cytometry ; Humans ; Lupus Coagulation Inhibitor ; Male ; Middle Aged ; P-Selectin/genetics ; Thrombosis/blood ; Thrombosis/immunology ; beta 2-Glycoprotein I/pharmacology
Czasopismo naukowe
Tytuł :
Early Inhibition of P-Selectin/P-Selectin Glycoprotein Ligand-1 Reduces Intimal Hyperplasia in Murine Vein Grafts through Platelet Adhesion.
Autorzy :
Tseng CN; Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.; Department of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chang YT; Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.; Department of Pediatric, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Yen CY; Department of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Lengquist M; Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.
Kronqvist M; Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.
Eriksson EE; Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.
Hedin U; Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.
Pokaż więcej
Źródło :
Thrombosis and haemostasis [Thromb Haemost] 2019 Dec; Vol. 119 (12), pp. 2014-2024. Date of Electronic Publication: 2019 Oct 21.
Typ publikacji :
Journal Article
MeSH Terms :
Platelet Adhesiveness*
Hyperplasia/*prevention & control
Membrane Glycoproteins/*blood
P-Selectin/*blood
Tunica Intima/*pathology
Veins/*transplantation
Animals ; Blood Platelets/pathology ; Disease Models, Animal ; Endothelial Cells ; Female ; Inflammation ; Leukocytes/metabolism ; Ligands ; Macrophages/metabolism ; Male ; Membrane Glycoproteins/antagonists & inhibitors ; Mice ; Mice, Inbred C57BL ; P-Selectin/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Severe COVID-19 Is a Microvascular Disease.
Autorzy :
Lowenstein CJ; Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD (C.J.L.).
Solomon SD; Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD (C.J.L.).
Pokaż więcej
Źródło :
Circulation [Circulation] 2020 Oct 27; Vol. 142 (17), pp. 1609-1611. Date of Electronic Publication: 2020 Sep 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus Infections/*pathology
Pneumonia, Viral/*pathology
Vascular Diseases/*pathology
Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/virology ; Cytokines/metabolism ; Endothelium/cytology ; Endothelium/metabolism ; Exocytosis ; Fibrin Fibrinogen Degradation Products/metabolism ; Humans ; Myocardial Infarction/complications ; Myocardial Infarction/pathology ; P-Selectin/antagonists & inhibitors ; P-Selectin/metabolism ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Severity of Illness Index ; Stroke/complications ; Stroke/pathology ; Vascular Diseases/complications ; von Willebrand Factor/antagonists & inhibitors ; von Willebrand Factor/metabolism
Czasopismo naukowe
Tytuł :
The vimentin rod domain blocks P-selectin-P-selectin glycoprotein ligand 1 interactions to attenuate leukocyte adhesion to inflamed endothelium.
Autorzy :
Lam, Fong Wilson (AUTHOR)
Brown, Cameron August (AUTHOR)
Valladolid, Christian (AUTHOR)
Emebo, Dabel Cynthia (AUTHOR)
Palzkill, Timothy Gerald (AUTHOR)
Cruz, Miguel Angel (AUTHOR)
Pokaż więcej
Źródło :
PLoS ONE. 10/13/2020, Vol. 15 Issue 10, p1-18. 18p.
Czasopismo naukowe
Tytuł :
Erythrocyte, Platelet, Serum Ferritin, and P-Selectin Pathophysiology Implicated in Severe Hypercoagulation and Vascular Complications in COVID-19.
Autorzy :
Venter C; Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Private Bag X1 Matieland, Stellenbosch 7602, South Africa.
Bezuidenhout JA; Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Private Bag X1 Matieland, Stellenbosch 7602, South Africa.
Laubscher GJ; Suite 104, 1 Elsie du Toit Street, Mediclinic Stellenbosch, Stellenbosch 7600, South Africa.
Lourens PJ; Suite 104, 1 Elsie du Toit Street, Mediclinic Stellenbosch, Stellenbosch 7600, South Africa.
Steenkamp J; PathCare Laboratories, PathCare Business Centre, PathCare Park, Neels Bothma Street, N1 City 7460, South Africa.
Kell DB; Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Private Bag X1 Matieland, Stellenbosch 7602, South Africa.; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Crown St, Liverpool L69 7ZB, UK.; The Novo Nordisk Foundation Centre for Biosustainability, Building 220, Kemitorvet, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.
Pretorius E; Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Private Bag X1 Matieland, Stellenbosch 7602, South Africa.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 03; Vol. 21 (21). Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Platelets/*pathology
Cardiovascular Diseases/*virology
Coronavirus Infections/*blood
Coronavirus Infections/*pathology
Erythrocytes/*pathology
Ferritins/*blood
P-Selectin/*blood
Pneumonia, Viral/*blood
Pneumonia, Viral/*pathology
Betacoronavirus/isolation & purification ; Blood Coagulation/physiology ; Blood Platelets/virology ; COVID-19 ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/pathology ; Coronavirus Infections/virology ; Erythrocytes/virology ; Female ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Thrombosis/pathology ; Thrombosis/virology
Czasopismo naukowe
Tytuł :
Role of Extracellular Vesicles in Pulmonary Arterial Hypertension: Modulation of Pulmonary Endothelial Function and Angiogenesis.
Autorzy :
Khandagale A; From the Department of Medical Sciences, Cardiology and Clinical Chemistry (A.K.), Uppsala University, Sweden.
Åberg M; Department of Medical Sciences, Clinical Chemistry (M.Å., A.S.), Uppsala University, Sweden.
Wikström G; Department of Medical Sciences, Cardiology and Internal Medicine (G.W.), Uppsala University, Sweden.
Bergström Lind S; Department of Chemistry - BMC, Analytical Chemistry (S.B.L., G.S.), Uppsala University, Sweden.
Shevchenko G; Department of Chemistry - BMC, Analytical Chemistry (S.B.L., G.S.), Uppsala University, Sweden.
Björklund E; Department of Medical Sciences, Cardiology (E.B., C.C.), Uppsala University, Sweden.
Siegbahn A; Department of Medical Sciences, Clinical Chemistry (M.Å., A.S.), Uppsala University, Sweden.
Christersson C; Department of Medical Sciences, Cardiology (E.B., C.C.), Uppsala University, Sweden.
Pokaż więcej
Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Sep; Vol. 40 (9), pp. 2293-2309. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neovascularization, Physiologic*
Endothelial Cells/*metabolism
Endothelium, Vascular/*metabolism
Extracellular Vesicles/*metabolism
Pulmonary Arterial Hypertension/*metabolism
Pulmonary Artery/*metabolism
Aged ; Case-Control Studies ; Cells, Cultured ; Cross-Sectional Studies ; Endothelial Cells/ultrastructure ; Endothelium, Vascular/physiopathology ; Endothelium, Vascular/ultrastructure ; Extracellular Vesicles/ultrastructure ; Female ; Fibroblast Growth Factor 2/metabolism ; Humans ; Intercellular Adhesion Molecule-1/metabolism ; Male ; Membrane Glycoproteins/metabolism ; Middle Aged ; P-Selectin/metabolism ; Pulmonary Arterial Hypertension/pathology ; Pulmonary Arterial Hypertension/physiopathology ; Pulmonary Artery/physiopathology ; Pulmonary Artery/ultrastructure ; Signal Transduction ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor Receptor-1/metabolism
Czasopismo naukowe
Tytuł :
Platelet P-selectin triggers rapid surface exposure of tissue factor in monocytes.
Autorzy :
Ivanov II; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom.
Apta BHR; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom.
Bonna AM; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Harper MT; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom. .
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2019 Sep 16; Vol. 9 (1), pp. 13397. Date of Electronic Publication: 2019 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Platelet Activation*
Blood Platelets/*metabolism
Monocytes/*metabolism
P-Selectin/*metabolism
Thromboplastin/*metabolism
Blood Coagulation ; Cell Communication ; Humans ; P-Selectin/genetics ; Thromboplastin/genetics
Czasopismo naukowe
Tytuł :
P-selectin plays a role in haem-induced acute lung injury in sickle mice.
Autorzy :
Ghosh S; Division of Hematology/Oncology, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Center for Translational and International Hematology, Vascular Medicine Institute, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Flage B; Center for Translational and International Hematology, Vascular Medicine Institute, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Weidert F; Center for Translational and International Hematology, Vascular Medicine Institute, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Ofori-Acquah SF; Division of Hematology/Oncology, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Center for Translational and International Hematology, Vascular Medicine Institute, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; School of Biomedical and Allied Health Sciences, University of Ghana, Accra, Ghana.
Pokaż więcej
Źródło :
British journal of haematology [Br J Haematol] 2019 Jul; Vol. 186 (2), pp. 329-333. Date of Electronic Publication: 2019 Feb 27.
Typ publikacji :
Letter; Research Support, N.I.H., Extramural
MeSH Terms :
Acute Lung Injury/*metabolism
Anemia, Sickle Cell/*metabolism
Heme/*metabolism
P-Selectin/*metabolism
Acute Lung Injury/genetics ; Acute Lung Injury/pathology ; Anemia, Sickle Cell/genetics ; Anemia, Sickle Cell/pathology ; Animals ; Disease Models, Animal ; Heme/genetics ; Mice ; Mice, Mutant Strains ; P-Selectin/genetics
Raport
Tytuł :
Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma.
Autorzy :
Federico C; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Alhallak K; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Biomedical Engineering, Washington University, St. Louis, MO, USA.
Sun J; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Biomedical Engineering, Washington University, St. Louis, MO, USA.
Duncan K; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Azab F; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Sudlow GP; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
de la Puente P; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Muz B; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Kapoor V; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Zhang L; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Biomedical Engineering, Washington University, St. Louis, MO, USA.
Yuan F; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pharmaceutical and Administrative Sciences, St. Louis College of Pharmacy, St. Louis, MO, USA.
Markovic M; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pharmaceutical and Administrative Sciences, St. Louis College of Pharmacy, St. Louis, MO, USA.
Kotsybar J; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pharmaceutical and Administrative Sciences, St. Louis College of Pharmacy, St. Louis, MO, USA.
Wasden K; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Guenthner N; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Gurley S; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.
King J; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Kohnen D; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Salama NN; Department of Pharmaceutical and Administrative Sciences, St. Louis College of Pharmacy, St. Louis, MO, USA.; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Thotala D; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Hallahan DE; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Vij R; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
DiPersio JF; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Achilefu S; Department of Biomedical Engineering, Washington University, St. Louis, MO, USA.; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Azab AK; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA. .; Department of Biomedical Engineering, Washington University, St. Louis, MO, USA. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2020 Nov 27; Vol. 11 (1), pp. 6037. Date of Electronic Publication: 2020 Nov 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Tumor Microenvironment*/drug effects
Bortezomib/*therapeutic use
Multiple Myeloma/*drug therapy
Multiple Myeloma/*pathology
Nanoparticles/*chemistry
Protein Kinase Inhibitors/*therapeutic use
rho-Associated Kinases/*antagonists & inhibitors
Amides/pharmacology ; Amides/therapeutic use ; Animals ; Apoptosis/drug effects ; Bortezomib/pharmacology ; Cell Adhesion/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Disease Progression ; Focal Adhesion Protein-Tyrosine Kinases/metabolism ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Liposomes ; Membrane Glycoproteins/metabolism ; Mice ; P-Selectin/metabolism ; Protein Binding ; Protein Kinase Inhibitors/pharmacology ; Pyridines/pharmacology ; Pyridines/therapeutic use ; Signal Transduction/drug effects ; Tumor Burden ; rho-Associated Kinases/metabolism ; src-Family Kinases/metabolism
Czasopismo naukowe
Tytuł :
Isolation and Functional Identification of an Antiplatelet RGD-Containing Disintegrin from Cerastes cerastes Venom.
Autorzy :
Ameziani M; USTHB, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, BP 32 El-Alia, Bab Ezzouar, Algiers, Algeria.
Chérifi F; USTHB, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, BP 32 El-Alia, Bab Ezzouar, Algiers, Algeria.
Kiheli H; USTHB, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, BP 32 El-Alia, Bab Ezzouar, Algiers, Algeria.
Saoud S; USTHB, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, BP 32 El-Alia, Bab Ezzouar, Algiers, Algeria.
Hariti G; Faculty of Medicine, Blood Transfusion Center, Unverisity of Benyoucef Benkheda Algiers 1, CHU Bab El-Oued, Algiers, Algeria.
Kellou-Taîri S; USTHB, Laboratory of Theoretical Physico-Chemistry and Computer Chemistry, Faculty of Chemistry, BP 32 El-Alia, Bab Ezzouar, Algiers, Algeria.
Laraba-Djebari F; USTHB, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, BP 32 El-Alia, Bab Ezzouar, Algiers, Algeria. .
Pokaż więcej
Źródło :
The protein journal [Protein J] 2020 Oct; Vol. 39 (5), pp. 574-590. Date of Electronic Publication: 2020 Sep 22.
Typ publikacji :
Journal Article
MeSH Terms :
Oligopeptides*
Platelet Aggregation Inhibitors*/chemistry
Platelet Aggregation Inhibitors*/isolation & purification
Platelet Aggregation Inhibitors*/pharmacology
Viperidae*
Viper Venoms/*chemistry
Animals ; Blood Platelets/metabolism ; Mice ; P-Selectin/metabolism ; Platelet Glycoprotein GPIIb-IIIa Complex/metabolism
Czasopismo naukowe
Tytuł :
Platelet and Vascular Biomarkers Associate With Thrombosis and Death in Coronavirus Disease.
Autorzy :
Barrett TJ; Department of Medicine (T.J.B., A.H.L., Y.X., J.H., J.S.B.), New York University Grossman School of Medicine, NY.
Lee AH; Department of Medicine (T.J.B., A.H.L., Y.X., J.H., J.S.B.), New York University Grossman School of Medicine, NY.
Xia Y; Department of Medicine (T.J.B., A.H.L., Y.X., J.H., J.S.B.), New York University Grossman School of Medicine, NY.
Lin LH; Department of Pathology (L.H.L., M.B., P.C.), New York University Grossman School of Medicine, NY.
Black M; Department of Pathology (L.H.L., M.B., P.C.), New York University Grossman School of Medicine, NY.
Cotzia P; Department of Pathology (L.H.L., M.B., P.C.), New York University Grossman School of Medicine, NY.; Center for Biospecimen Research Development (P.C.), New York University Grossman School of Medicine, NY.
Hochman J; Department of Medicine (T.J.B., A.H.L., Y.X., J.H., J.S.B.), New York University Grossman School of Medicine, NY.
Berger JS; Department of Medicine (T.J.B., A.H.L., Y.X., J.H., J.S.B.), New York University Grossman School of Medicine, NY.; Department of Surgery (J.S.B.), New York University Grossman School of Medicine, NY.
Pokaż więcej
Źródło :
Circulation research [Circ Res] 2020 Sep 11; Vol. 127 (7), pp. 945-947. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Mean Platelet Volume*
Coronavirus Infections/*blood
Pneumonia, Viral/*blood
Thrombosis/*blood
Aged ; Biomarkers/blood ; CD40 Antigens/blood ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/mortality ; Coronavirus Infections/pathology ; Female ; Hemoglobins/analysis ; Humans ; Lymphocyte Count ; Male ; Middle Aged ; P-Selectin/blood ; Pandemics ; Platelet Count ; Pneumonia, Viral/complications ; Pneumonia, Viral/mortality ; Pneumonia, Viral/pathology ; Thrombosis/etiology ; Thromboxane B2/blood
Raport
Tytuł :
Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19.
Autorzy :
Hottz ED; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.; Laboratory of Immunothrombosis, Department of Biochemistry, Federal University of Juiz de Fora (UFJF), Juiz de Fora, Minas Gerais, Brazil.
Azevedo-Quintanilha IG; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Palhinha L; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Teixeira L; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Barreto EA; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Pão CRR; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Righy C; Paulo Niemeyer State Brain Institute, Rio de Janeiro, Brazil.; National Institute of Infectious Disease Evandro Chagas and.
Franco S; Paulo Niemeyer State Brain Institute, Rio de Janeiro, Brazil.
Souza TML; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.; Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation, Rio de Janeiro, Brazil; and.
Kurtz P; Paulo Niemeyer State Brain Institute, Rio de Janeiro, Brazil.; D'Or Institute for Research and Education, Rio de Janeiro, Brazil.
Bozza FA; National Institute of Infectious Disease Evandro Chagas and.; D'Or Institute for Research and Education, Rio de Janeiro, Brazil.
Bozza PT; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Pokaż więcej
Źródło :
Blood [Blood] 2020 Sep 10; Vol. 136 (11), pp. 1330-1341.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Betacoronavirus/*immunology
Blood Coagulation Disorders/*pathology
Blood Platelets/*pathology
Coronavirus Infections/*complications
Monocytes/*pathology
Pneumonia, Viral/*complications
Thromboplastin/*metabolism
Adult ; Biomarkers/metabolism ; Blood Coagulation Disorders/immunology ; Blood Coagulation Disorders/metabolism ; Blood Coagulation Disorders/virology ; Blood Platelets/metabolism ; Blood Platelets/virology ; COVID-19 ; Case-Control Studies ; Coronavirus Infections/immunology ; Coronavirus Infections/metabolism ; Coronavirus Infections/virology ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Monocytes/metabolism ; Monocytes/virology ; P-Selectin/metabolism ; Pandemics ; Platelet Activation ; Pneumonia, Viral/immunology ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/virology ; Prognosis ; Prospective Studies ; SARS-CoV-2 ; Survival Rate
Czasopismo naukowe
Tytuł :
IL-18, VCAM-1 and P-selectin as early biomarkers in normoalbuminuric Type 2 diabetes patients.
Autorzy :
Al-Rubeaan K; Department of Medicine, University Diabetes Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Nawaz SS; Biochemistry Department, Strategic Center for Diabetes Research, King Saud University, Riyadh, Saudi Arabia.
Youssef AM; Biochemistry Department, Registry Department, University Diabetes Center, King Saud University, Riyadh, Saudi Arabia.
Al Ghonaim M; College of Medicine, King Khalid Universe Hospital, King Saud University, Riyadh, Saudi Arabia.
Siddiqui K; Biochemistry Department, Strategic Center for Diabetes Research, King Saud University, Riyadh, Saudi Arabia.
Pokaż więcej
Źródło :
Biomarkers in medicine [Biomark Med] 2019 Apr; Vol. 13 (6), pp. 467-478. Date of Electronic Publication: 2019 Jun 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 2/*blood
Diabetes Mellitus, Type 2/*urine
Interleukin-18/*metabolism
P-Selectin/*metabolism
Vascular Cell Adhesion Molecule-1/*metabolism
Biomarkers/blood ; Biomarkers/urine ; Diabetes Mellitus, Type 2/physiopathology ; Female ; Glomerular Filtration Rate ; Humans ; Interleukin-18/blood ; Interleukin-18/urine ; Kidney/physiopathology ; Male ; Middle Aged ; P-Selectin/blood ; P-Selectin/urine ; Vascular Cell Adhesion Molecule-1/blood ; Vascular Cell Adhesion Molecule-1/urine
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies