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Tytuł :
Penaeidins restrict white spot syndrome virus infection by antagonizing the envelope proteins to block viral entry.
Autorzy :
Xiao B; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)/ School of Marine Sciences, Sun Yat-sen University, Guangzhou, P. R. People's Republic of China.; State Key Laboratory of Biocontrol/ School of Life Sciences, Sun Yat-sen University, Guangzhou, P. R. People's Republic of China.
Fu Q; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)/ School of Marine Sciences, Sun Yat-sen University, Guangzhou, P. R. People's Republic of China.; State Key Laboratory of Biocontrol/ School of Life Sciences, Sun Yat-sen University, Guangzhou, P. R. People's Republic of China.
Niu S; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)/ School of Marine Sciences, Sun Yat-sen University, Guangzhou, P. R. People's Republic of China.; State Key Laboratory of Biocontrol/ School of Life Sciences, Sun Yat-sen University, Guangzhou, P. R. People's Republic of China.
Zhu P; Guangxi Key Laboratory of Beibu Gulf Marine Biodiversity Conservation, Beibu Gluf University, Qinzhou, P. R. People's Republic of China.
He J; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)/ School of Marine Sciences, Sun Yat-sen University, Guangzhou, P. R. People's Republic of China.; State Key Laboratory of Biocontrol/ School of Life Sciences, Sun Yat-sen University, Guangzhou, P. R. People's Republic of China.
Li C; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)/ School of Marine Sciences, Sun Yat-sen University, Guangzhou, P. R. People's Republic of China.; State Key Laboratory of Biocontrol/ School of Life Sciences, Sun Yat-sen University, Guangzhou, P. R. People's Republic of China.
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Źródło :
Emerging microbes & infections [Emerg Microbes Infect] 2020 Dec; Vol. 9 (1), pp. 390-412.
Typ publikacji :
Journal Article
MeSH Terms :
Peptides*/genetics
Peptides*/pharmacology
Antiviral Agents/*pharmacology
Penaeidae/*virology
White spot syndrome virus 1/*drug effects
Animals ; Antimicrobial Cationic Peptides/genetics ; Antimicrobial Cationic Peptides/pharmacology ; Gene Expression ; Hemocytes/virology ; Viral Envelope Proteins/drug effects ; Virus Internalization/drug effects ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł :
A two-pronged attack.
Autorzy :
Feng JJ; Department of Chemistry & Loker Hydrocarbon Research Institute, University of Southern California, Los Angeles, CA, USA.
Zhang C; Department of Chemistry & Loker Hydrocarbon Research Institute, University of Southern California, Los Angeles, CA, USA. .
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Źródło :
Nature chemical biology [Nat Chem Biol] 2020 Nov; Vol. 16 (11), pp. 1154-1155.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Peptides*
Proto-Oncogene Proteins B-raf*
Intercellular Signaling Peptides and Proteins
Czasopismo naukowe
Tytuł :
Maternally inherited peptides as strain-specific chemosignals.
Autorzy :
Kaba H; Department of Physiology, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan; .
Fujita H; Department of Physiology, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.
Agatsuma T; Department of Environmental Health Sciences, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.
Matsunami H; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710; .; Department of Neurobiology, Duke University Medical Center, Durham, NC 27710.; Duke Institute for Brain Sciences, Duke University, Durham, NC 27710.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Dec 01; Vol. 117 (48), pp. 30738-30743. Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Maternal Inheritance*
Pheromones*
Peptides/*genetics
Peptides/*metabolism
Animals ; Female ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Male ; Mice ; Mice, Inbred BALB C ; Mitochondria/genetics ; Mitochondria/metabolism ; NADH Dehydrogenase/genetics ; NADH Dehydrogenase/metabolism ; Olfactory Bulb ; Pregnancy ; Sexual Behavior, Animal ; Species Specificity
Czasopismo naukowe
Tytuł :
Development of histidine-tagged cyclic peptide functionalized monolithic material for the affinity purification of antibodies in biological matrices.
Autorzy :
Xu R; Institute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Lu L; Institute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Guangzhou 510632, China; Laboratory of Analytical Pharmaceutical Chemistry, Department of Pharmaceutical Sciences, CIRM, University of Liege, CHU B36, B-4000, Liege, Belgium.
Sun L; Institute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Liu X; Institute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Lei Y; Institute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Huang S; Institute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Huang H; Institute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Crommen J; Institute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Guangzhou 510632, China; Laboratory of Analytical Pharmaceutical Chemistry, Department of Pharmaceutical Sciences, CIRM, University of Liege, CHU B36, B-4000, Liege, Belgium.
Han H; Institute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Guangzhou 510632, China; Department of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine & New Drug Research, Jinan University, Guangzhou 510632, China. Electronic address: .
Wang Q; Institute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Guangzhou 510632, China; Department of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine & New Drug Research, Jinan University, Guangzhou 510632, China. Electronic address: .
Jiang Z; Institute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Guangzhou 510632, China; Department of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine & New Drug Research, Jinan University, Guangzhou 510632, China. Electronic address: .
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2021 Jan 04; Vol. 1635, pp. 461707. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Monoclonal/*isolation & purification
Chromatography, Affinity/*methods
Histidine/*metabolism
Peptides, Cyclic/*chemistry
Adsorption ; Chelating Agents ; Humans ; Immunoglobulin G/blood ; Immunoglobulin G/isolation & purification ; Ligands ; Peptides/metabolism ; Peptides, Cyclic/metabolism ; Sepharose
Czasopismo naukowe
Tytuł :
RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation.
Autorzy :
Li T; UPMC Hillman Cancer Center, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA.
Wang X; UPMC Hillman Cancer Center, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA.
Ju E; UPMC Hillman Cancer Center, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA.
da Silva SR; UPMC Hillman Cancer Center, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA.
Chen L; UPMC Hillman Cancer Center, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA.
Zhang X; UPMC Hillman Cancer Center, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA.
Wei S; UPMC Hillman Cancer Center, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA.
Gao SJ; UPMC Hillman Cancer Center, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 16; Vol. 12 (1), pp. 1055. Date of Electronic Publication: 2021 Feb 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Proteolysis*/drug effects
Ubiquitination*/drug effects
Carcinogenesis/*metabolism
Carcinogenesis/*pathology
Intracellular Signaling Peptides and Proteins/*metabolism
Mechanistic Target of Rapamycin Complex 1/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Animals ; Arginine/metabolism ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Disease Progression ; Female ; Intercellular Signaling Peptides and Proteins/pharmacology ; Kinetics ; Lysine/metabolism ; Mice, Nude ; Phosphorylation/drug effects ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł :
Fluorescent Leakage Assay to Investigate Membrane Destabilization by Cell-Penetrating Peptide.
Autorzy :
Konate K; PHYMEDEXP, INSERM U1046 - CNRS UMR 9214 - University of Montpellier.
Seisel Q; PHYMEDEXP, INSERM U1046 - CNRS UMR 9214 - University of Montpellier.
Vivès E; PHYMEDEXP, INSERM U1046 - CNRS UMR 9214 - University of Montpellier.
Boisguérin P; PHYMEDEXP, INSERM U1046 - CNRS UMR 9214 - University of Montpellier.
Deshayes S; PHYMEDEXP, INSERM U1046 - CNRS UMR 9214 - University of Montpellier; .
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2020 Dec 19 (166). Date of Electronic Publication: 2020 Dec 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Biological Assay/*methods
Cell Membrane/*metabolism
Cell-Penetrating Peptides/*chemistry
Arginine/chemistry ; Fluorescence ; Lipid Bilayers/chemistry ; Nanoparticles/chemistry ; Peptides/metabolism ; RNA, Small Interfering/metabolism ; Unilamellar Liposomes/chemistry
Czasopismo naukowe
Tytuł :
Antimicrobial peptides as a promising treatment option against Acinetobacter baumannii infections.
Autorzy :
Neshani A; Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran; Department of Laboratory Sciences, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran; Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Sedighian H; Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Mirhosseini SA; Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Ghazvini K; Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Zare H; Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
Jahangiri A; Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: .
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Źródło :
Microbial pathogenesis [Microb Pathog] 2020 Sep; Vol. 146, pp. 104238. Date of Electronic Publication: 2020 May 05.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Acinetobacter Infections/*drug therapy
Antimicrobial Cationic Peptides/*pharmacology
Acinetobacter baumannii/drug effects ; Anti-Bacterial Agents/pharmacology ; Antimicrobial Cationic Peptides/chemistry ; Carbapenems/pharmacology ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/pharmacology ; Drug Resistance, Bacterial ; Histatins/pharmacology ; Humans ; Intercellular Signaling Peptides and Proteins/chemistry ; Intercellular Signaling Peptides and Proteins/pharmacology ; Microbial Sensitivity Tests ; Peptides, Cyclic/chemistry ; Peptides, Cyclic/pharmacology ; Pore Forming Cytotoxic Proteins/pharmacology ; Wasp Venoms/chemistry ; Wasp Venoms/pharmacology ; beta-Lactam Resistance
Czasopismo naukowe
Tytuł :
Sequence Decoding of 1D to 2D Self-Assembling Cyclic Peptides.
Autorzy :
Díaz S; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, Santiago de Compostela, 15782, Spain.
Insua I; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, Santiago de Compostela, 15782, Spain.
Bhak G; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, Santiago de Compostela, 15782, Spain.
Montenegro J; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, Santiago de Compostela, 15782, Spain.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Nov 17; Vol. 26 (64), pp. 14765-14770. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article
MeSH Terms :
Nanotubes*
Peptides, Cyclic*
Peptides/*chemistry
Water
Czasopismo naukowe
Tytuł :
Hepatocyte expression of the micropeptide adropin regulates the liver fasting response and is enhanced by caloric restriction.
Autorzy :
Banerjee S; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Ghoshal S; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Stevens JR; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
McCommis KS; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.; Center for Cardiovascular Research, Saint Louis University School of Medicine, St. Louis, Missouri, USA.; Saint Louis University Liver Center, Saint Louis University School of Medicine, St. Louis, Missouri USA.
Gao S; Department of Metabolism and Aging, Scripps Research Institute, Jupiter, Florida, USA.
Castro-Sepulveda M; Laboratorio de Ciencias del Ejercicio. Facultad de Medicina, Universidad Finis Terrae, Santiago, Chile.
Mizgier ML; Departamento de Ciencias de la SaludCarrera de Nutrición y Dietética and Departamento de Nutrición, Diabetes y Metabolismo, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Girardet C; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Kumar KG; Department of Metabolism and Aging, Scripps Research Institute, Jupiter, Florida, USA.
Galgani JE; Departamento de Ciencias de la SaludCarrera de Nutrición y Dietética and Departamento de Nutrición, Diabetes y Metabolismo, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Niehoff ML; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, Missouri, USA.; Division of Geriatric Medicine, Saint Louis University School of Medicine, St. Louis, Saint Louis University School of Medicine.; Research Service, John Cochran Division, Saint Louis Veterans Affairs Medical Center, Missouri, USA.
Farr SA; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, Missouri, USA.; Division of Geriatric Medicine, Saint Louis University School of Medicine, St. Louis, Saint Louis University School of Medicine.; Research Service, John Cochran Division, Saint Louis Veterans Affairs Medical Center, Missouri, USA.
Zhang J; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Butler AA; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA .; Department of Metabolism and Aging, Scripps Research Institute, Jupiter, Florida, USA.; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Oct 02; Vol. 295 (40), pp. 13753-13768. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Caloric Restriction*
Fasting*
Gene Expression Regulation*
Hepatocytes/*metabolism
Intercellular Signaling Peptides and Proteins/*biosynthesis
Liver/*metabolism
Animals ; Cyclic AMP-Dependent Protein Kinases/genetics ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Gluconeogenesis/genetics ; Hepatocytes/cytology ; Intercellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/biosynthesis ; Intracellular Signaling Peptides and Proteins/genetics ; Liver/cytology ; Mice ; Mice, Knockout ; Phosphoenolpyruvate Carboxykinase (GTP)/biosynthesis ; Phosphoenolpyruvate Carboxykinase (GTP)/genetics ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
Antimicrobial Peptides: Vestiges of Past or Modern Therapeutics?
Autorzy :
Mitra JB; Radiopharmaceuticals Division, Anushaktinagar, Mumbai- 400094, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai- 400094, India.
Sharma VK; Homi Bhabha National Institute, Anushaktinagar, Mumbai- 400094, India.; Solid State Physics Division, Anushaktinagar, Mumbai- 400094, India.
Kumar M; Homi Bhabha National Institute, Anushaktinagar, Mumbai- 400094, India.; Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre (BARC), Mumbai 400085, India.
Mukherjee A; Radiopharmaceuticals Division, Anushaktinagar, Mumbai- 400094, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai- 400094, India.
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Źródło :
Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2020; Vol. 20 (3), pp. 183-195.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antimicrobial Cationic Peptides*/chemistry
Antimicrobial Cationic Peptides*/immunology
Antimicrobial Cationic Peptides*/pharmacology
Drug Discovery*
Anti-Infective Agents/*pharmacology
Drug Resistance, Multiple/*drug effects
Oligopeptides/*pharmacology
Peptides, Cyclic/*pharmacology
Amino Acid Sequence ; Animals ; Anti-Infective Agents/administration & dosage ; Anti-Infective Agents/chemistry ; Communicable Diseases/diagnosis ; Communicable Diseases/drug therapy ; Communicable Diseases/microbiology ; Evolution, Molecular ; Humans ; Oligopeptides/chemistry ; Oligopeptides/immunology ; Peptides, Cyclic/chemistry ; Peptides, Cyclic/immunology ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Insights into the mechanism of action of two analogues of aurein 2.2.
Autorzy :
Raheem N; Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada.
Kumar P; Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada.
Lee E; Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada.
Cheng JTJ; Centre for Microbial Diseases and Immunity Research, Department of Microbiology and Immunology, University of British Columbia, 2259 Lower Mall Research Station, Vancouver, British Columbia V6T 1Z4, Canada.
Hancock REW; Centre for Microbial Diseases and Immunity Research, Department of Microbiology and Immunology, University of British Columbia, 2259 Lower Mall Research Station, Vancouver, British Columbia V6T 1Z4, Canada.
Straus SK; Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2020 Jun 01; Vol. 1862 (6), pp. 183262. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimicrobial Cationic Peptides/*chemistry
Amphibian Proteins/chemistry ; Amphibians ; Animals ; Antimicrobial Cationic Peptides/pharmacology ; Cell-Penetrating Peptides/chemistry ; Drug Discovery ; Gram-Positive Bacteria/drug effects ; Protein Conformation ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Peptides derived from small mitochondrial open reading frames: Genomic, biological, and therapeutic implications.
Autorzy :
Miller B; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Kim SJ; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Kumagai H; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA; Graduate School of Health and Sports Science, Juntendo University, Chiba, Japan.
Mehta HH; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Xiang W; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Liu J; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Yen K; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Cohen P; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2020 Aug 15; Vol. 393 (2), pp. 112056. Date of Electronic Publication: 2020 May 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
DNA, Mitochondrial/*genetics
Mitochondria/*metabolism
Open Reading Frames/*genetics
Peptides/*genetics
Cardiovascular Diseases/genetics ; Genomics/methods ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Mitochondria/genetics ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism ; Peptides/metabolism
Czasopismo naukowe
Tytuł :
Chemoproteomic-Driven Discovery of Covalent PROTACs.
Autorzy :
Zhou Y; CAS Key Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology , Chinese Academy of Sciences , Shanghai 200032 , China.
Xiao Y; CAS Key Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology , Chinese Academy of Sciences , Shanghai 200032 , China.
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Źródło :
Biochemistry [Biochemistry] 2020 Jan 21; Vol. 59 (2), pp. 128-129. Date of Electronic Publication: 2019 Sep 20.
Typ publikacji :
Editorial; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Peptides*
Intercellular Signaling Peptides and Proteins ; Proteolysis
Raport
Tytuł :
A new molecular probe: An NRP-1 targeting probe for the grading diagnosis of glioma in nude mice.
Autorzy :
Wu W; Department of Neurology, Specialty Medical Center of People's Armed Police Force, Tianjin, 300162, China; Department of Neurology, The 985th Hospital of the Joint Logistics Support Force, Taiyuan, 030001, China.
Zhong S; Department of Neurology, Specialty Medical Center of People's Armed Police Force, Tianjin, 300162, China.
Gong Y; Institute of Disaster Medicine, Tianjin University, Tianjin 300072, China.
Shan Y; Department of Neurology, Specialty Medical Center of People's Armed Police Force, Tianjin, 300162, China.
Yuan L; Department of Neurology, The 985th Hospital of the Joint Logistics Support Force, Taiyuan, 030001, China.
Wang L; Nursing Department, People's Hospital of Yu ci, Jinzhong, 030600, China.
Chen J; Graduate Department, Logistics University of People's Armed Police Force, Tianjin, 300309, China. Electronic address: .
Zhang Z; Graduate Department, Logistics University of People's Armed Police Force, Tianjin, 300309, China. Electronic address: .
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Źródło :
Neuroscience letters [Neurosci Lett] 2020 Jan 01; Vol. 714, pp. 134617. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Contrast Media*
Dextrans*/ultrastructure
Magnetite Nanoparticles*/ultrastructure
Peptides, Cyclic*
Polyethylene Glycols*
Glioma/*diagnostic imaging
Neuropilin-1/*metabolism
Animals ; Cell Line, Tumor ; Cell-Penetrating Peptides ; Dynamic Light Scattering ; Glioma/metabolism ; Glioma/pathology ; Magnetic Resonance Imaging ; Mice ; Mice, Nude ; Microscopy, Electron, Transmission ; Molecular Probes/ultrastructure ; Neoplasm Grading ; RNA Interference ; Transfection
Czasopismo naukowe
Tytuł :
A Global Review on Short Peptides: Frontiers and Perspectives.
Autorzy :
Apostolopoulos V; Institute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.
Bojarska J; Institute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Żeromskiego 116, 90-924 Lodz, Poland.
Chai TT; Department of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar 31900, Malaysia.
Elnagdy S; Botany and Microbiology Department, Faculty of Science, Cairo University, Gamaa St., Giza 12613, Egypt.
Kaczmarek K; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Żeromskiego 116, 90-924 Lodz, Poland.
Matsoukas J; Institute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.; NewDrug, Patras Science Park, 26500 Patras, Greece.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.
New R; Vaxcine (UK) Ltd., c/o London Bioscience Innovation Centre, London NW1 0NH, UK.; Faculty of Science & Technology, Middlesex University, The Burroughs, London NW4 4BT, UK.
Parang K; Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, Irvine, CA 92618, USA.
Lopez OP; Centro de Investigación y de Estudios Avanzados del IPN, Departamento de Biotecnología y Bioquímica, Irapuato 36824, Guanajuato, Mexico.
Parhiz H; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073, USA.
Perera CO; School of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Pickholz M; Departamento de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires 1428, Argentina.; Instituto de Física de Buenos Aires (IFIBA, UBA-CONICET), Argentina, Buenos Aires 1428, Argentina.
Remko M; Remedika, Luzna 9, 85104 Bratislava, Slovakia.
Saviano M; Institute of Crystallography (CNR), Via Amendola 122/o, 70126 Bari, Italy.
Skwarczynski M; School of Chemistry & Molecular Biosciences, The University of Queensland, St Lucia, QLD 4072, Australia.
Tang Y; Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (MOE), School of Pharma Ceutical Sciences, Tsinghua University, Beijing 100084, China.
Wolf WM; Institute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Żeromskiego 116, 90-924 Lodz, Poland.
Yoshiya T; Peptide Institute, Inc., Osaka 567-0085, Japan.
Zabrocki J; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Żeromskiego 116, 90-924 Lodz, Poland.
Zielenkiewicz P; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.; Department of Systems Biology, Institute of Experimental Plant Biology and Biotechnology, University of Warsaw, Miecznikowa 1, 02-096 Warsaw, Poland.
AlKhazindar M; Botany and Microbiology Department, Faculty of Science, Cairo University, Gamaa St., Giza 12613, Egypt.
Barriga V; Institute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.
Kelaidonis K; NewDrug, Patras Science Park, 26500 Patras, Greece.
Sarasia EM; Faculty of Science & Technology, Middlesex University, The Burroughs, London NW4 4BT, UK.
Toth I; School of Chemistry & Molecular Biosciences, The University of Queensland, St Lucia, QLD 4072, Australia.; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia.; School of Pharmacy, The University of Queensland, Woolloongabba, QLD 4102, Australia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jan 15; Vol. 26 (2). Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anti-Infective Agents/*pharmacology
Antiviral Agents/*pharmacology
Peptides/*chemistry
Peptides/*pharmacology
Peptides/*therapeutic use
Amino Acids/chemistry ; Anti-Infective Agents/chemistry ; Antiviral Agents/chemistry ; COVID-19/drug therapy ; Computer Simulation ; Cosmeceuticals/chemistry ; Cosmeceuticals/therapeutic use ; Dietary Supplements ; Gene Transfer Techniques ; Humans ; Lactoferrin/chemistry ; Lipid Bilayers ; Nanostructures/administration & dosage ; Nanostructures/chemistry ; Peptides/administration & dosage ; Stem Cells ; Vaccines, Subunit/chemistry ; Vaccines, Subunit/pharmacology
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Monocyclic Peptides: Types, Synthesis and Applications.
Autorzy :
Khazaei-Poul Y; Department of Medical Biotechnology, School of Advanced Technology in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Farhadi S; Department of Medical Biotechnology, School of Advanced Technology in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ghani S; Department of Medical Biotechnology, School of Advanced Technology in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ahmadizad SA; Department of Medical Biotechnology, School of Advanced Technology in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ranjbari J; Cellular and Molecular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
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Źródło :
Current pharmaceutical biotechnology [Curr Pharm Biotechnol] 2021; Vol. 22 (1), pp. 123-135.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Peptide Library*
Anti-Infective Agents/*chemical synthesis
Antineoplastic Agents/*chemical synthesis
Peptides, Cyclic/*chemical synthesis
Anti-Infective Agents/chemistry ; Anti-Infective Agents/pharmacology ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Cyclization ; Drug Delivery Systems/methods ; Green Chemistry Technology ; Humans ; Ligands ; Peptide Biosynthesis, Nucleic Acid-Independent ; Peptides, Cyclic/chemistry ; Peptides, Cyclic/pharmacology ; Protein Hydrolysates/chemical synthesis ; Protein Hydrolysates/chemistry ; Protein Hydrolysates/pharmacology ; Solid-Phase Synthesis Techniques
Czasopismo naukowe
Tytuł :
Design and validation of a frugal, automated, solid-phase peptide synthesizer.
Autorzy :
Kallmyer NE; Department of Chemical and Biological Engineering, Iowa State University, Ames, Iowa, United States of America.
Rider NE; Department of Chemical and Biological Engineering, Iowa State University, Ames, Iowa, United States of America.
Reuel NF; Department of Chemical and Biological Engineering, Iowa State University, Ames, Iowa, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Aug 19; Vol. 15 (8), pp. e0237473. Date of Electronic Publication: 2020 Aug 19 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Peptides/*chemical synthesis
Solid-Phase Synthesis Techniques/*methods
Amino Acid Sequence ; Automation ; Cell-Penetrating Peptides/chemical synthesis ; Cell-Penetrating Peptides/chemistry ; Equipment Design ; Fluorometry ; Nanostructures/chemistry ; Oxidation-Reduction ; Peptides/chemistry ; Solid-Phase Synthesis Techniques/economics ; Solid-Phase Synthesis Techniques/instrumentation
Czasopismo naukowe
Tytuł :
Membrane pore-formation correlates with the hydrophilic angle of histidine-rich amphipathic peptides with multiple biological activities.
Autorzy :
Lointier M; Université de Strasbourg/CNRS, UMR7177, Institut de Chimie, 4, Rue Blaise Pascal, 67070 Strasbourg, France.
Aisenbrey C; Université de Strasbourg/CNRS, UMR7177, Institut de Chimie, 4, Rue Blaise Pascal, 67070 Strasbourg, France.
Marquette A; Université de Strasbourg/CNRS, UMR7177, Institut de Chimie, 4, Rue Blaise Pascal, 67070 Strasbourg, France.
Tan JH; Université de Strasbourg/CNRS, UMR7177, Institut de Chimie, 4, Rue Blaise Pascal, 67070 Strasbourg, France.
Kichler A; Université de Strasbourg/CNRS, UMR7199, Laboratoire de Conception et Application de Molécules Bioactives, Faculté de Pharmacie, 67401 Illkirch, France.
Bechinger B; Université de Strasbourg/CNRS, UMR7177, Institut de Chimie, 4, Rue Blaise Pascal, 67070 Strasbourg, France; Institut Universitaire de France. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2020 Aug 01; Vol. 1862 (8), pp. 183212. Date of Electronic Publication: 2020 Feb 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimicrobial Cationic Peptides/*pharmacology
DNA/*genetics
Histidine/*genetics
Membranes/*drug effects
Alanine/genetics ; Antimicrobial Cationic Peptides/chemistry ; Antimicrobial Cationic Peptides/genetics ; Cell Line, Tumor ; Cell-Penetrating Peptides/chemistry ; Cell-Penetrating Peptides/genetics ; Cell-Penetrating Peptides/pharmacology ; DNA/drug effects ; Humans ; Hydrophobic and Hydrophilic Interactions/drug effects ; Lentivirus/genetics ; Leucine/genetics ; Membranes/metabolism ; Porosity ; Transfection
Czasopismo naukowe
Tytuł :
Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Autorzy :
Wells JN; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Buschauer R; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Mackens-Kiani T; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Best K; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Kratzat H; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Berninghausen O; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Becker T; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Gilbert W; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America.
Cheng J; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Beckmann R; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
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Źródło :
PLoS biology [PLoS Biol] 2020 Jul 20; Vol. 18 (7), pp. e3000780. Date of Electronic Publication: 2020 Jul 20 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Cycle Proteins/*chemistry
Cell Cycle Proteins/*metabolism
Intracellular Signaling Peptides and Proteins/*chemistry
Intracellular Signaling Peptides and Proteins/*metabolism
Ribosomal Proteins/*chemistry
Ribosomal Proteins/*metabolism
Ribosomes/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*chemistry
Saccharomyces cerevisiae Proteins/*metabolism
Adaptor Proteins, Signal Transducing/metabolism ; Amino Acid Sequence ; Binding Sites ; Conserved Sequence ; Evolution, Molecular ; HEK293 Cells ; Humans ; Models, Molecular ; Peptides/chemistry ; Protein Binding ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Transfer/metabolism ; RNA-Binding Proteins/metabolism ; Ribosomes/ultrastructure ; Saccharomyces cerevisiae/ultrastructure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
FAM83G Is a Novel Inducer of Apoptosis.
Autorzy :
Okada J; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi 371-8511, Japan.
Sunaga N; Department of Respiratory Medicine, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi 371-8511, Japan.
Yamada E; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi 371-8511, Japan.
Saito T; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi 371-8511, Japan.
Ozawa A; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi 371-8511, Japan.
Nakajima Y; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi 371-8511, Japan.
Okada K; Omagari Kosei Medical Center, 8-65 Omagaritori-machi, Daisen 014-0027, Japan.
Pessin JE; Department of Medicine and Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Okada S; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi 371-8511, Japan.
Yamada M; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi 371-8511, Japan.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Jun 18; Vol. 25 (12). Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Carcinoma, Non-Small-Cell Lung/*metabolism
Intracellular Signaling Peptides and Proteins/*metabolism
Lung Neoplasms/*metabolism
Neoplasm Proteins/*metabolism
Alcohol Oxidoreductases ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; HCT116 Cells ; Hep G2 Cells ; Humans ; Intracellular Signaling Peptides and Proteins/antagonists & inhibitors ; Intracellular Signaling Peptides and Proteins/genetics ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Neoplasm Proteins/antagonists & inhibitors ; Neoplasm Proteins/genetics ; Peptides/chemical synthesis ; Peptides/chemistry ; Peptides/pharmacology ; Phosphorylation
Czasopismo naukowe

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