Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""PHARMACOLOGY"" wg kryterium: Temat


Starter badań:

Tytuł :
A framework for simplification of quantitative systems pharmacology models in clinical pharmacology.
Autorzy :
Derbalah A; School of Pharmacy, University of Otago, Dunedin, New Zealand.
Al-Sallami H; School of Pharmacy, University of Otago, Dunedin, New Zealand.
Hasegawa C; School of Pharmacy, University of Otago, Dunedin, New Zealand.
Gulati A; Clinical Pharmacology and Exploratory Development, Astellas Pharma Global Development, Northbrook, Illinois, USA.
Duffull SB; School of Pharmacy, University of Otago, Dunedin, New Zealand.
Pokaż więcej
Źródło :
British journal of clinical pharmacology [Br J Clin Pharmacol] 2022 Feb; Vol. 88 (4), pp. 1430-1440. Date of Electronic Publication: 2020 Jul 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Pharmacology*/methods
Pharmacology, Clinical*
Computer Simulation ; Drug Development/methods ; Humans ; Models, Biological ; Network Pharmacology
Czasopismo naukowe
Tytuł :
Effects and Mechanisms of Rhus chinensis Mill. Fruits on Suppressing RANKL-Induced Osteoclastogenesis by Network Pharmacology and Validation in RAW264.7 Cells.
Autorzy :
Zheng Y; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China.
Zhao L; Beijing Engineering and Technology Research Center of Food Additives, Beijing Technology and Business University, Beijing 100048, China.
Yi J; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China.
Cai S; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China.
Pokaż więcej
Źródło :
Nutrients [Nutrients] 2022 Feb 28; Vol. 14 (5). Date of Electronic Publication: 2022 Feb 28.
Typ publikacji :
Journal Article
MeSH Terms :
Osteogenesis*
RANK Ligand*/metabolism
RANK Ligand*/pharmacology
Rhus*/chemistry
Plant Extracts/*pharmacology
Animals ; Cell Differentiation ; Fruit/chemistry ; Mice ; Network Pharmacology ; RAW 264.7 Cells
Czasopismo naukowe
Tytuł :
Review of applications and challenges of quantitative systems pharmacology modeling and machine learning for heart failure.
Autorzy :
Cheng L; Quantitative Systems Pharmacology and Physiologically Based Pharmacokinetics, Bristol Myers Squibb, Princeton, NJ, 08536, USA. .
Qiu Y; Department of Mathematics, Michigan State University, East Lansing, MI, 48824, USA.
Schmidt BJ; Quantitative Systems Pharmacology and Physiologically Based Pharmacokinetics, Bristol Myers Squibb, Princeton, NJ, 08536, USA.
Wei GW; Department of Mathematics, Michigan State University, East Lansing, MI, 48824, USA.; Department of Electrical and Computer Engineering, Michigan State University, East Lansing, MI, 48824, USA.; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA.
Pokaż więcej
Źródło :
Journal of pharmacokinetics and pharmacodynamics [J Pharmacokinet Pharmacodyn] 2022 Feb; Vol. 49 (1), pp. 39-50. Date of Electronic Publication: 2021 Oct 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
Heart Failure*/diagnosis
Heart Failure*/drug therapy
Pharmacology*
Calibration ; Humans ; Machine Learning ; Models, Biological ; Network Pharmacology
Czasopismo naukowe
Tytuł :
Recent applications of quantitative systems pharmacology and machine learning models across diseases.
Autorzy :
Aghamiri SS; Department of Biochemistry, University of Nebraska-Lincoln, Lincoln, NE, USA.
Amin R; Department of Biochemistry, University of Nebraska-Lincoln, Lincoln, NE, USA. .
Helikar T; Department of Biochemistry, University of Nebraska-Lincoln, Lincoln, NE, USA. .
Pokaż więcej
Źródło :
Journal of pharmacokinetics and pharmacodynamics [J Pharmacokinet Pharmacodyn] 2022 Feb; Vol. 49 (1), pp. 19-37. Date of Electronic Publication: 2021 Oct 20.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Pharmacology*/methods
Systems Biology*/methods
Drug Development/methods ; Machine Learning ; Models, Biological ; Network Pharmacology
Czasopismo naukowe
Tytuł :
Potential Mechanisms of Triptolide against Diabetic Cardiomyopathy Based on Network Pharmacology Analysis and Molecular Docking.
Autorzy :
Zhu N; Department of Cardiology, The Third Affiliated Hospital of Shanghai University (Wenzhou People's Hospital), No. 299 Guan Road, Wenzhou, 325000 Zhejiang Province, China.
Huang B; Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan West Road, Wenzhou, 325000 Zhejiang Province, China.
Zhu L; Department of General Practice, The Third Affiliated Hospital of Shanghai University (Wenzhou People's Hospital), No. 299 Guan Road, Wenzhou, 325000 Zhejiang Province, China.
Wang Y; Department of Cardiology, The Third Affiliated Hospital of Shanghai University (Wenzhou People's Hospital), No. 299 Guan Road, Wenzhou, 325000 Zhejiang Province, China.
Pokaż więcej
Źródło :
Journal of diabetes research [J Diabetes Res] 2021 Dec 07; Vol. 2021, pp. 9944589. Date of Electronic Publication: 2021 Dec 07 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Docking Simulation*
Network Pharmacology*
Cardiovascular Agents/*pharmacology
Diabetic Cardiomyopathies/*drug therapy
Diterpenes/*pharmacology
Myocytes, Cardiac/*drug effects
Phenanthrenes/*pharmacology
Caco-2 Cells ; Databases, Genetic ; Diabetic Cardiomyopathies/genetics ; Diabetic Cardiomyopathies/metabolism ; Diabetic Cardiomyopathies/pathology ; Epoxy Compounds/pharmacology ; Gene Regulatory Networks ; Humans ; Molecular Structure ; Molecular Targeted Therapy ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; Protein Interaction Maps ; Signal Transduction ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Systematically identifying the anti-inflammatory constituents of Cimicifuga dahurica by UPLC-Q/TOF-MS combined with network pharmacology analysis.
Autorzy :
Pang QQ; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, China.
Li T; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, China.
Liu LX; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, China.
Shi DF; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, China.
Yao XS; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, China.
Li HB; Jiangsu Kanion Pharmaceutical Co. Ltd. and State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Lianyungang, Jiangsu, China.
Yu Y; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, China.
Pokaż więcej
Źródło :
Biomedical chromatography : BMC [Biomed Chromatogr] 2021 Dec; Vol. 35 (12), pp. e5177. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents*/chemistry
Anti-Inflammatory Agents*/pharmacology
Plant Extracts*/chemistry
Plant Extracts*/pharmacology
Cimicifuga/*chemistry
Network Pharmacology/*methods
Animals ; Cell Survival/drug effects ; Chromatography, High Pressure Liquid/methods ; Mass Spectrometry/methods ; Mice ; RAW 264.7 Cells ; Rats ; Triterpenes/analysis ; Triterpenes/chemistry ; Triterpenes/pharmacology
Czasopismo naukowe
Tytuł :
Systematic investigation for the mechanisms and the substance basis of Yang-Xin-Ding-Ji capsule based on the metabolite profile and network pharmacology.
Autorzy :
Wu Y; Department of Pharmacy, Hebei General Hospital, Shijiazhuang, Hebei, People's Republic of China.; Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing, People's Republic of China.
Qiu Z; Department of Pharmacy, Hebei General Hospital, Shijiazhuang, Hebei, People's Republic of China.
Ren B; Department of Pharmacy, Hebei General Hospital, Shijiazhuang, Hebei, People's Republic of China.
Sui F; Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing, People's Republic of China.
Pokaż więcej
Źródło :
Biomedical chromatography : BMC [Biomed Chromatogr] 2021 Dec; Vol. 35 (12), pp. e5202. Date of Electronic Publication: 2021 Aug 22.
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal*/chemistry
Drugs, Chinese Herbal*/pharmacology
Metabolic Networks and Pathways/*drug effects
Network Pharmacology/*methods
Animals ; Chromatography, High Pressure Liquid/methods ; Databases, Genetic ; Flavonoids/chemistry ; Flavonoids/pharmacology ; Humans ; Male ; Mass Spectrometry/methods ; Protein Interaction Maps/drug effects ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Applications of Quantitative System Pharmacology Modeling to Model-Informed Drug Development.
Autorzy :
Zhu AZX; Preclinical and Translational Sciences, Takeda Pharmaceuticals International Co, Cambridge, MA, USA. .
Rogge M; Center for Pharmacometrics and Systems Pharmacology, University of Florida, Lake Nona, FL, USA.
Pokaż więcej
Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2486, pp. 71-86.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Biological*
Pharmacology*
Drug Development ; Humans ; Network Pharmacology
Czasopismo naukowe
Tytuł :
Network Pharmacology Analysis of Hewei Jiangni Granule for Gastroesophageal Reflux Disease and Experimental Verification of Its Anti-Neurogenic Inflammation Mechanism.
Autorzy :
Cheng Y; Second Clinical Medical College, Beijing University of Chinese Medicine, Beijing, People's Republic of China.; Department of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Kou F; Second Clinical Medical College, Beijing University of Chinese Medicine, Beijing, People's Republic of China.; Department of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Zhang X; Second Clinical Medical College, Beijing University of Chinese Medicine, Beijing, People's Republic of China.; Department of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Dai Y; Department of Pharmacotherapy and Oriental Medicine, School of Pharmacy, Hyogo University of Health Sciences, Hyogo, Japan.
Shi L; Department of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Xie C; Department of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Li X; Department of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Li J; Department of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Pokaż więcej
Źródło :
Drug design, development and therapy [Drug Des Devel Ther] 2022 May 05; Vol. 16, pp. 1349-1363. Date of Electronic Publication: 2022 May 05 (Print Publication: 2022).
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Gastroesophageal Reflux*/drug therapy
Animals ; Anti-Inflammatory Agents/pharmacology ; Humans ; Medicine, Chinese Traditional ; Mice ; Molecular Docking Simulation ; Network Pharmacology ; Neurogenic Inflammation
Czasopismo naukowe
Tytuł :
Anti-inflammatory mechanism of rhein in treating asthma based on network pharmacology.
Autorzy :
Junfang F; Department of Pediatrics, the Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250033, China.
Ou C; School of Nursing, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Yibiao W; Department of Pediatrics, the Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250033, China.
Pokaż więcej
Źródło :
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan [J Tradit Chin Med] 2022 Apr; Vol. 42 (2), pp. 296-303.
Typ publikacji :
Journal Article
MeSH Terms :
Asthma*/drug therapy
Asthma*/genetics
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Mitogen-Activated Protein Kinase 14*
Anthraquinones ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; ErbB Receptors/genetics ; Humans ; Inflammation/drug therapy ; NF-kappa B/genetics ; Network Pharmacology
Czasopismo naukowe
Tytuł :
Exploring the Potential Antidepressant Mechanisms of Pinellia by Using the Network Pharmacology and Molecular Docking.
Autorzy :
Xiao YG; Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, People's Republic of China.
Wu HB; Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, People's Republic of China.
Chen JS; Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, People's Republic of China.
Li X; Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, People's Republic of China. .; School of Clinical Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510080, People's Republic of China. .
Qiu ZK; Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, People's Republic of China. .
Pokaż więcej
Źródło :
Metabolic brain disease [Metab Brain Dis] 2022 Apr; Vol. 37 (4), pp. 1071-1094. Date of Electronic Publication: 2022 Mar 01.
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Pinellia*
Antidepressive Agents/pharmacology ; Antidepressive Agents/therapeutic use ; Humans ; Molecular Docking Simulation ; Network Pharmacology ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
A network pharmacology approach to investigate the anticancer mechanism of cinobufagin against hepatocellular carcinoma via downregulation of EGFR-CDK2 signaling.
Autorzy :
Yang AL; School of Pharmacy, Binzhou Medical University, Yantai 264003, China.
Wu Q; School of Pharmacy, Binzhou Medical University, Yantai 264003, China.
Hu ZD; Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China.
Wang SP; School of Pharmacy, Binzhou Medical University, Yantai 264003, China.
Tao YF; School of Pharmacy, Binzhou Medical University, Yantai 264003, China.
Wang AM; School of Pharmacy, Binzhou Medical University, Yantai 264003, China.
Sun YX; School of Pharmacy, Binzhou Medical University, Yantai 264003, China.
Li XL; School of Pharmacy, Binzhou Medical University, Yantai 264003, China.
Dai L; School of Pharmacy, Binzhou Medical University, Yantai 264003, China. Electronic address: .
Zhang J; School of Pharmacy, Binzhou Medical University, Yantai 264003, China. Electronic address: .
Pokaż więcej
Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Nov 15; Vol. 431, pp. 115739. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Network Pharmacology*
Antineoplastic Agents/*pharmacology
Bufanolides/*pharmacology
Carcinoma, Hepatocellular/*drug therapy
Cyclin-Dependent Kinase 2/*metabolism
Liver Neoplasms/*drug therapy
Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Carcinoma, Hepatocellular/enzymology ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; Cell Proliferation/drug effects ; Cyclin-Dependent Kinase 2/antagonists & inhibitors ; Cyclin-Dependent Kinase 2/genetics ; Down-Regulation ; Drug Synergism ; ErbB Receptors/antagonists & inhibitors ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Gefitinib/pharmacology ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Hep G2 Cells ; Humans ; Liver Neoplasms/enzymology ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; M Phase Cell Cycle Checkpoints/drug effects ; Protein Interaction Maps ; Protein Kinase Inhibitors/pharmacology ; Purines/pharmacology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Mechanism of Rhizoma Coptidis in epilepsy with network pharmacology.
Autorzy :
Huang D; Department of Neurology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, China.
Lv Y; Department of Neurology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, China.
Lu C; Department of Neurology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, China.
Zhang B; Department of Neurology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, China.
Fu Z; Department of Neurology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, China.
Huang Y; Department of Neurology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, China; .
Pokaż więcej
Źródło :
Allergologia et immunopathologia [Allergol Immunopathol (Madr)] 2022 May 01; Vol. 50 (3), pp. 138-150. Date of Electronic Publication: 2022 May 01 (Print Publication: 2022).
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Epilepsy*/drug therapy
Humans ; Molecular Docking Simulation ; Network Pharmacology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Potential efficacious materials investigation of Yi-Yi Mixture based on Metabolome-oriented network pharmacology strategy.
Autorzy :
Gong GW; Department of General Surgery, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine, Nanjing 210000, China.
Tang WH; Department of General Surgery, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine, Nanjing 210000, China.
Zhou Z; Laboratory of Hospital Chinese Medicine Preparation, Department of Pharmacy, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine, Nanjing 210023, China.
Jiang YW; Laboratory of Hospital Chinese Medicine Preparation, Department of Pharmacy, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine, Nanjing 210023, China.
Wang CZ; Department of General Surgery, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine, Nanjing 210000, China.
Cheng H; Department of General Surgery, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine, Nanjing 210000, China.
Cao Y; Laboratory of Hospital Chinese Medicine Preparation, Department of Pharmacy, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine, Nanjing 210023, China. Electronic address: .
Jiang ZW; Department of General Surgery, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine, Nanjing 210000, China. Electronic address: .
Pokaż więcej
Źródło :
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2022 May 01; Vol. 1197, pp. 123199. Date of Electronic Publication: 2022 Feb 28.
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal*/analysis
Drugs, Chinese Herbal*/pharmacology
Pancreatitis*
Acute Disease ; Animals ; Chromatography, High Pressure Liquid/methods ; Metabolome ; Molecular Docking Simulation ; Network Pharmacology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Protective effect of total Saponins from American ginseng against cigarette smoke-induced COPD in mice based on integrated metabolomics and network pharmacology.
Autorzy :
Lin H; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Wang C; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Yu H; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Liu Y; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Tan L; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
He S; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Li Z; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Wang C; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China; Research Center of Natural Drug, Jilin University, Changchun 130021, China.
Wang F; College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Li P; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China; Research Center of Natural Drug, Jilin University, Changchun 130021, China.
Liu J; School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China; Research Center of Natural Drug, Jilin University, Changchun 130021, China. Electronic address: .
Pokaż więcej
Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 May; Vol. 149, pp. 112823. Date of Electronic Publication: 2022 Mar 23.
Typ publikacji :
Journal Article
MeSH Terms :
Cigarette Smoking*
Panax*/chemistry
Pulmonary Disease, Chronic Obstructive*/drug therapy
Pulmonary Disease, Chronic Obstructive*/prevention & control
Saponins*/metabolism
Saponins*/pharmacology
Saponins*/therapeutic use
Animals ; Biomarkers/metabolism ; Metabolomics/methods ; Mice ; Molecular Docking Simulation ; Network Pharmacology
Czasopismo naukowe
Tytuł :
Network pharmacology prediction and molecular docking-based strategy to explore the potential mechanism of Huanglian Jiedu Decoction against sepsis.
Autorzy :
Li X; College of Pharmacy, Southern Medical University, Guangzhou, China; Department of Pharmacy, Chinese PLA General Hospital, Beijing, China.
Wei S; Department of Pharmacy, Chinese PLA General Hospital, Beijing, China.
Niu S; Department of Pharmacy, Chinese PLA General Hospital, Beijing, China.
Ma X; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Li H; Department of Pharmacy, Chinese PLA General Hospital, Beijing, China.
Jing M; Department of Pharmacy, Chinese PLA General Hospital, Beijing, China.
Zhao Y; College of Pharmacy, Southern Medical University, Guangzhou, China; Department of Pharmacy, Chinese PLA General Hospital, Beijing, China. Electronic address: .
Pokaż więcej
Źródło :
Computers in biology and medicine [Comput Biol Med] 2022 May; Vol. 144, pp. 105389. Date of Electronic Publication: 2022 Mar 09.
Typ publikacji :
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms :
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Sepsis*/drug therapy
Humans ; Molecular Docking Simulation ; Network Pharmacology ; Phosphatidylinositol 3-Kinases ; Quercetin
Czasopismo naukowe
Tytuł :
The Network Pharmacology Study of Dahuang Fuzi Decoction for Treating Incomplete Intestinal Obstruction.
Autorzy :
Guo JF; Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611130, China.
Zhao YT; Tianjin University of Traditional Chinese Medicine, Tianjin 3016172, China.
Du QY; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
Ren Y; Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611130, China.
Wang Y; Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611130, China.
Wang ZX; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
Jin W; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
Pokaż więcej
Źródło :
BioMed research international [Biomed Res Int] 2022 Apr 28; Vol. 2022, pp. 2775434. Date of Electronic Publication: 2022 Apr 28 (Print Publication: 2022).
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Intestinal Obstruction*
Diterpenes ; Flavonoids ; Humans ; Kaempferols/pharmacology ; Medicine, Chinese Traditional ; Molecular Docking Simulation ; Network Pharmacology ; Phosphatidylinositol 3-Kinases ; Proto-Oncogene Proteins c-akt
Czasopismo naukowe
Tytuł :
Identification of Bioactive Compounds and Potential Mechanisms of Kuntai Capsule in the Treatment of Polycystic Ovary Syndrome by Integrating Network Pharmacology and Bioinformatics.
Autorzy :
Li X; Department of Obstetrics and Gynecology, Shenzhen University General Hospital, Shenzhen, Guangdong, China.; Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, Guangdong, China.; Shenzhen Key Laboratory, Shenzhen University General Hospital, Shenzhen, Guangdong, China.
Ma J; School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, Guangdong, China.
Guo L; School of Pharmaceutical Sciences, Health Science Center, Shenzhen University, Shenzhen, Guangdong, China.
Dong C; Department of Obstetrics and Gynecology, Shenzhen University General Hospital, Shenzhen, Guangdong, China.
Zhu G; Department of Obstetrics and Gynecology, Shenzhen University General Hospital, Shenzhen, Guangdong, China.
Hong W; Department of Obstetrics and Gynecology, Shenzhen University General Hospital, Shenzhen, Guangdong, China.
Chen C; Department of Obstetrics and Gynecology, Shenzhen University General Hospital, Shenzhen, Guangdong, China.
Wang H; Department of Obstetrics and Gynecology, Shenzhen University General Hospital, Shenzhen, Guangdong, China.; Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, Guangdong, China.; Shenzhen Key Laboratory, Shenzhen University General Hospital, Shenzhen, Guangdong, China.
Wu X; Department of Obstetrics and Gynecology, Shenzhen University General Hospital, Shenzhen, Guangdong, China.; Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, Guangdong, China.; Clinical Medical Academy, Shenzhen University, Shenzhen, Guangdong, China.
Pokaż więcej
Źródło :
Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2022 Apr 28; Vol. 2022, pp. 3145938. Date of Electronic Publication: 2022 Apr 28 (Print Publication: 2022).
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal*/chemistry
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Polycystic Ovary Syndrome*/drug therapy
Polycystic Ovary Syndrome*/genetics
Computational Biology ; Female ; Humans ; Medicine, Chinese Traditional ; Molecular Docking Simulation ; Network Pharmacology ; Quercetin/pharmacology ; Quercetin/therapeutic use
Czasopismo naukowe
Tytuł :
Integrated Network Pharmacology and Metabolomics Analysis to Reveal the Potential Mechanism of Siwu Paste on Aplastic Anemia Induced by Chemotherapy Drugs.
Autorzy :
He D; Hunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, 410013, People's Republic of China.
Dan W; Hunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, 410013, People's Republic of China.
Du Q; Hunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, 410013, People's Republic of China.
Shen BB; Hunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, 410013, People's Republic of China.
Chen L; Hunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, 410013, People's Republic of China.
Fang LZ; Hunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, 410013, People's Republic of China.
Kuang JJ; Hunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, 410013, People's Republic of China.
Tang CY; Hunan Times Sunshine Pharmaceutical Co., Ltd., Changsha, Hunan, 425007, People's Republic of China.
Cai P; Hunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, 410013, People's Republic of China.
Yu R; Hunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, 410013, People's Republic of China.; Hunan Key Laboratory of TCM Prescription and Syndromes Translational Medicine Hunan, Changsha, Hunan, 410208, People's Republic of China.
Zhang SH; Hunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, 410013, People's Republic of China.
Huang JH; Hunan Academy of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, 410013, People's Republic of China.; Hunan Key Laboratory of TCM Prescription and Syndromes Translational Medicine Hunan, Changsha, Hunan, 410208, People's Republic of China.
Pokaż więcej
Źródło :
Drug design, development and therapy [Drug Des Devel Ther] 2022 Apr 28; Vol. 16, pp. 1231-1254. Date of Electronic Publication: 2022 Apr 28 (Print Publication: 2022).
Typ publikacji :
Journal Article
MeSH Terms :
Anemia, Aplastic*/chemically induced
Anemia, Aplastic*/drug therapy
Drugs, Chinese Herbal*/pharmacology
Humans ; Metabolomics/methods ; Network Pharmacology ; Sphingolipids
Czasopismo naukowe
Tytuł :
Network Pharmacology-Based Approach Combined with Bioinformatic Analytics to Elucidate the Potential of Curcumol against Hepatocellular Carcinoma.
Autorzy :
Huang X; Faculty of Dentistry, University of Debrecen, 4032 Debrecen, Hungary.
Rehman HM; Alnoorians Group of Institutes 55-Elahi Bukhsh Park, Amir Road, Shad Bagh, Lahore 54000, Pakistan.; School of Biochemistry and Biotechnology, University of the Punjab, Lahore 54590, Pakistan.
Szöllősi AG; Department of Immunology, University of Debrecen, 4032 Debrecen, Hungary.
Zhou S; Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Pokaż więcej
Źródło :
Genes [Genes (Basel)] 2022 Apr 07; Vol. 13 (4). Date of Electronic Publication: 2022 Apr 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/metabolism
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Liver Neoplasms*/drug therapy
Liver Neoplasms*/genetics
Liver Neoplasms*/metabolism
Sesquiterpenes*/pharmacology
Computational Biology ; Humans ; Molecular Docking Simulation ; Network Pharmacology
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies