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Wyszukujesz frazę ""PLATELET-derived growth factor"" wg kryterium: Temat


Tytuł :
Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor.
Autorzy :
Sherafat A; Department of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.
Pfeiffer F; Department of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.; Department of Physiology, University of Tübingen, Tübingen, Germany.
Reiss AM; Department of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.
Wood WM; Department of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.
Nishiyama A; Department of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA. .; Institute for Systems Genomics, University of Connecticut, Storrs, CT, USA. .; The Connecticut Institute for the Brain and Cognitive Sciences, University of Connecticut, Storrs, CT, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Apr 15; Vol. 12 (1), pp. 2265. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Remyelination*
Demyelinating Diseases/*pathology
Microglia/*physiology
Neuropilin-1/*metabolism
Oligodendrocyte Precursor Cells/*physiology
Receptor, Platelet-Derived Growth Factor alpha/*metabolism
Animals ; Cell Differentiation ; Cell Lineage ; Cell Proliferation ; Cells, Cultured ; Cerebellum/cytology ; Cerebellum/growth & development ; Corpus Callosum/cytology ; Corpus Callosum/drug effects ; Corpus Callosum/growth & development ; Corpus Callosum/pathology ; Demyelinating Diseases/chemically induced ; Disease Models, Animal ; Female ; Humans ; Lysophosphatidylcholines/administration & dosage ; Lysophosphatidylcholines/toxicity ; Male ; Mice ; Mice, Transgenic ; Microglia/drug effects ; Microglia/ultrastructure ; Microscopy, Electron, Transmission ; Models, Animal ; Myelin Sheath/metabolism ; Neuropilin-1/genetics ; Oligodendroglia/physiology ; Platelet-Derived Growth Factor/metabolism ; Primary Cell Culture
Czasopismo naukowe
Tytuł :
Chrysin Stimulates Subcutaneous Fat Thermogenesis in Mice by Regulating PDGFRα and MicroRNA Expressions.
Autorzy :
Wang X; School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui 230009, China.
Cai H; School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui 230009, China.
Shui S; School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui 230009, China.
Lin Y; School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui 230009, China.
Wang F; School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui 230009, China.
Wang L; School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui 230009, China.
Chen J; School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui 230009, China.
Liu J; School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui 230009, China.; Engineering Research Center of Bioprocess, Ministry of Education, Hefei University of Technology, Hefei 230009, China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2021 Jun 02; Vol. 69 (21), pp. 5897-5906. Date of Electronic Publication: 2021 May 24.
Typ publikacji :
Journal Article
MeSH Terms :
MicroRNAs*/genetics
MicroRNAs*/metabolism
Receptor, Platelet-Derived Growth Factor alpha*/genetics
Receptor, Platelet-Derived Growth Factor alpha*/metabolism
Adipose Tissue, Brown/metabolism ; Adipose Tissue, White/metabolism ; Animals ; Diet, High-Fat/adverse effects ; Energy Metabolism ; Flavonoids/metabolism ; Mice ; Mice, Inbred C57BL ; Subcutaneous Fat/metabolism ; Thermogenesis ; Uncoupling Protein 1/genetics ; Uncoupling Protein 1/metabolism
Czasopismo naukowe
Tytuł :
Mutations of the c-Kit and PDGFRA gene in gastrointestinal stromal tumors among hakka population of Southern China.
Autorzy :
Wang S; Center for Digestive Diseases, Meizhou People's Hospital (Huangtang Hospital); Center for Precision Medicine; Guangdong Provincial Key Laboratory of Precision Medicine, Clinical and Translational Research in Hakka Population, Meizhou People's Hospital, No. 63 Huangtang Road, Meijiang District, Meizhou, PR China.
Zhang Q; Center for Precision Medicine; Guangdong Provincial Key Laboratory of Precision Medicine, Clinical and Translational Research in Hakka Population, Meizhou People's Hospital; Guangdong Provincial Engineering and Technology Research Center for Clinical Molecular Diagnostics and Antibody Therapeutics, No. 63 Huangtang Road, Meijiang District, Meizhou, PR China.
Wu H; Center for Precision Medicine; Guangdong Provincial Key Laboratory of Precision Medicine, Clinical and Translational Research in Hakka Population, Meizhou People's Hospital; Guangdong Provincial Engineering and Technology Research Center for Clinical Molecular Diagnostics and Antibody Therapeutics, No. 63 Huangtang Road, Meijiang District, Meizhou, PR China.
Yang Z; Center for Digestive Diseases, Meizhou People's Hospital (Huangtang Hospital); Center for Precision Medicine; Guangdong Provincial Key Laboratory of Precision Medicine, Clinical and Translational Research in Hakka Population, Meizhou People's Hospital, No. 63 Huangtang Road, Meijiang District, Meizhou, PR China.
Guo X; Center for Precision Medicine; Guangdong Provincial Key Laboratory of Precision Medicine, Clinical and Translational Research in Hakka Population, Meizhou People's Hospital; Guangdong Provincial Engineering and Technology Research Center for Clinical Molecular Diagnostics and Antibody Therapeutics, No. 63 Huangtang Road, Meijiang District, Meizhou, PR China.
Wang F; Center for Digestive Diseases, Meizhou People's Hospital (Huangtang Hospital); Center for Precision Medicine; Guangdong Provincial Key Laboratory of Precision Medicine, Clinical and Translational Research in Hakka Population, Meizhou People's Hospital, No. 63 Huangtang Road, Meijiang District, Meizhou, PR China.
Yu Z; Center for Precision Medicine; Guangdong Provincial Key Laboratory of Precision Medicine, Clinical and Translational Research in Hakka Population, Meizhou People's Hospital; Guangdong Provincial Engineering and Technology Research Center for Clinical Molecular Diagnostics and Antibody Therapeutics, No. 63 Huangtang Road, Meijiang District, Meizhou, PR China.
Zhong Z; Center for Precision Medicine; Guangdong Provincial Key Laboratory of Precision Medicine, Clinical and Translational Research in Hakka Population, Meizhou People's Hospital; Guangdong Provincial Engineering and Technology Research Center for Clinical Molecular Diagnostics and Antibody Therapeutics, No. 63 Huangtang Road, Meijiang District, Meizhou, PR China.
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Źródło :
Nigerian journal of clinical practice [Niger J Clin Pract] 2021 Jun; Vol. 24 (6), pp. 814-820.
Typ publikacji :
Journal Article
MeSH Terms :
Gastrointestinal Stromal Tumors*/ethnology
Gastrointestinal Stromal Tumors*/genetics
Proto-Oncogene Proteins c-kit*/genetics
Receptor, Platelet-Derived Growth Factor alpha*/genetics
China/epidemiology ; Humans ; Mutation
Czasopismo naukowe
Tytuł :
GYY4137 alleviates sepsis-induced acute lung injury in mice by inhibiting the PDGFRβ/Akt/NF-κB/NLRP3 pathway.
Autorzy :
Li J; Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Department of Critical Care Medicine, The First Affiliated Hospital, College of Medicine, Shihezi University, Shihezi 832000, China.
Ma J; Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Li M; Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Tao J; Department of Orthopedics, The Third Affiliated Hospital, College of Medicine, Shihezi University, Shihezi 832000, China.
Chen J; Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Yao C; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address: .
Yao S; Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Apr 15; Vol. 271, pp. 119192. Date of Electronic Publication: 2021 Feb 10.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Lung Injury/*drug therapy
Morpholines/*therapeutic use
NF-kappa B/*antagonists & inhibitors
NLR Family, Pyrin Domain-Containing 3 Protein/*antagonists & inhibitors
Organothiophosphorus Compounds/*therapeutic use
Proto-Oncogene Proteins c-akt/*antagonists & inhibitors
Receptor, Platelet-Derived Growth Factor beta/*antagonists & inhibitors
Sepsis/*drug therapy
Acute Lung Injury/etiology ; Acute Lung Injury/metabolism ; Animals ; Male ; Mice ; Mice, Inbred C57BL ; Morpholines/pharmacology ; NF-kappa B/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Organothiophosphorus Compounds/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; RAW 264.7 Cells ; Receptor, Platelet-Derived Growth Factor beta/metabolism ; Sepsis/complications ; Sepsis/metabolism ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Effect of Platelet-Derived Concentrated Growth Factor on Single-Layer, Multi-Layer, and Crushed Onlay Cartilage Grafts.
Autorzy :
Gürsoy K; Ankara Training and Research Hospital, Plastic, Reconstructive and Aesthetic Surgery Clinic, Ankara, Turkey.
Teymur H; Ankara Training and Research Hospital, Plastic, Reconstructive and Aesthetic Surgery Clinic, Ankara, Turkey.
Göktaş Demircan FB; Ankara Training and Research Hospital, Plastic, Reconstructive and Aesthetic Surgery Clinic, Ankara, Turkey.
Tanas Işikçi Ö; Ankara Training and Research Hospital, Pathology Clinic, Ankara, Turkey.
Gümüş M; Samsun Training and Research Hospital, Plastic, Reconstructive and Aesthetic Surgery Clinic, Samsun, Turkey.
Koçer U; Ankara Training and Research Hospital, Plastic, Reconstructive and Aesthetic Surgery Clinic, Ankara, Turkey.
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Źródło :
Aesthetic surgery journal [Aesthet Surg J] 2021 Apr 12; Vol. 41 (5), pp. 537-547.
Typ publikacji :
Journal Article
MeSH Terms :
Graft Survival*
Platelet-Derived Growth Factor*
Animals ; Cartilage ; Intercellular Signaling Peptides and Proteins ; Rabbits
Czasopismo naukowe
Tytuł :
Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors.
Autorzy :
Hosaka K; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77, Stockholm, Sweden.
Yang Y; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77, Stockholm, Sweden.; Department of Cellular and Genetic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Seki T; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77, Stockholm, Sweden.; Kagoshima University Graduate School of Medical and Dental Sciences, 890-8520, Kagoshima, Japan.
Du Q; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77, Stockholm, Sweden.
Jing X; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77, Stockholm, Sweden.; Department of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, 250033, China.
He X; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77, Stockholm, Sweden.
Wu J; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77, Stockholm, Sweden.
Zhang Y; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77, Stockholm, Sweden.; Medicine and Pharmacy Research Center, Binzhou Medical University, Yantai, 264003, Shandong, China.
Morikawa H; Unit of Computational Medicine, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, 171 76, Stockholm, Sweden.
Nakamura M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77, Stockholm, Sweden.; Department of Urology, The University of Tokyo Hospital 7-3-1, Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan.
Scherzer M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77, Stockholm, Sweden.
Sun X; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77, Stockholm, Sweden.; Department of Medical Oncology and Cancer Institute, Shuguang Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Xu Y; The State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 288 Nanjing Road, Tianjin, 300020, China.
Cheng T; The State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 288 Nanjing Road, Tianjin, 300020, China.
Li X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, 510060, Guangdong, China.
Liu X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, 510060, Guangdong, China.
Li Q; Department of Medical Oncology and Cancer Institute, Shuguang Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Liu Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, 510060, Guangdong, China.
Hong A; Department of Cell Biology, Institute of Biomedicine, Jinan University, Guangzhou, 510632, China.
Chen Y; Department of Emergency Medicine, Shandong Provincial Clinical Research Center for Emergency and Critical Care Medicine, Institute of Emergency and Critical Care Medicine of Shandong University, Qilu Hospital of Shandong University, Jinan, 250012, Shandong, China.
Cao Y; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 171 77, Stockholm, Sweden. .
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Źródło :
Nature communications [Nat Commun] 2020 Jul 24; Vol. 11 (1), pp. 3704. Date of Electronic Publication: 2020 Jul 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiogenesis Inhibitors/*pharmacology
Fibroblast Growth Factor 2/*drug effects
Fibroblast Growth Factor 2/*metabolism
Neoplasms/*drug therapy
Platelet-Derived Growth Factor/*drug effects
Vascular Endothelial Growth Factor A/*drug effects
Animals ; Biomarkers, Tumor ; Blood Pressure ; Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; Capillary Permeability ; Cell Proliferation ; Disease Models, Animal ; Drug Resistance, Neoplasm/drug effects ; Drug Therapy, Combination ; Humans ; Mice ; Mice, Inbred C57BL ; Neoplasms/pathology ; Neovascularization, Pathologic/drug therapy ; Platelet-Derived Growth Factor/metabolism ; Receptor, Platelet-Derived Growth Factor beta ; Signal Transduction/drug effects ; Tumor Hypoxia ; Tumor Microenvironment/drug effects ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł :
Inhibition of platelet-derived growth factor C and their receptors additionally increases doxorubicin effects in triple-negative breast cancer cells.
Autorzy :
Kim S; Department of Breast Cancer Center, Samsung Medical Center, 81 Irwon-Ro, Gangnam-gu, Seoul, 06351, South Korea. Electronic address: .
You D; Department of Breast Cancer Center, Samsung Medical Center, 81 Irwon-Ro, Gangnam-gu, Seoul, 06351, South Korea; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, 81 Irwon-Ro, Gangnam-gu, Seoul, 06351, South Korea.
Jeong Y; Department of Breast Cancer Center, Samsung Medical Center, 81 Irwon-Ro, Gangnam-gu, Seoul, 06351, South Korea; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, 81 Irwon-Ro, Gangnam-gu, Seoul, 06351, South Korea.
Yoon SY; Department of Breast Cancer Center, Samsung Medical Center, 81 Irwon-Ro, Gangnam-gu, Seoul, 06351, South Korea; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, 81 Irwon-Ro, Gangnam-gu, Seoul, 06351, South Korea.
Kim SA; Department of Breast Cancer Center, Samsung Medical Center, 81 Irwon-Ro, Gangnam-gu, Seoul, 06351, South Korea; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, 81 Irwon-Ro, Gangnam-gu, Seoul, 06351, South Korea.
Lee JE; Department of Breast Cancer Center, Samsung Medical Center, 81 Irwon-Ro, Gangnam-gu, Seoul, 06351, South Korea; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, 81 Irwon-Ro, Gangnam-gu, Seoul, 06351, South Korea; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Ro, Gangnam-gu, Seoul, 06351, South Korea. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Mar 15; Vol. 895, pp. 173868. Date of Electronic Publication: 2021 Jan 16.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Doxorubicin/*pharmacology
Imidazoles/*pharmacology
Lymphokines/*antagonists & inhibitors
Platelet-Derived Growth Factor/*antagonists & inhibitors
Pyridazines/*pharmacology
Receptors, Platelet-Derived Growth Factor/*antagonists & inhibitors
Sunitinib/*pharmacology
Triple Negative Breast Neoplasms/*drug therapy
Apoptosis/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Lymphokines/genetics ; Lymphokines/metabolism ; Matrix Metalloproteinase 1/metabolism ; Platelet-Derived Growth Factor/genetics ; Platelet-Derived Growth Factor/metabolism ; Receptors, Platelet-Derived Growth Factor/genetics ; Receptors, Platelet-Derived Growth Factor/metabolism ; Signal Transduction ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/metabolism ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Differentiated PDGFRα-Positive Cells: A Novel In-Vitro Model for Functional Studies of Neuronal Nitric Oxide Synthase.
Autorzy :
Mussa BM; Basic Medical Sciences Department, College of Medicine, University of Sharjah, Sharjah 27272, United Arab Emirates.
Khan AA; Department of Applied Biology, College of Science, University of Sharjah, Sharjah 27272, United Arab Emirates.
Srivastava A; Sharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.
Abdallah SH; Research Institute of Sciences & Engineering, University of Sharjah, Sharjah 27272, United Arab Emirates.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 29; Vol. 22 (7). Date of Electronic Publication: 2021 Mar 29.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Models, Biological*
Nitric Oxide Synthase Type I*
Receptor, Platelet-Derived Growth Factor alpha*
Interstitial Cells of Cajal/*enzymology
Mesenchymal Stem Cells/*physiology
Animals ; Bone Marrow ; Cells, Cultured ; Diabetes Complications ; Gastroparesis ; Humans ; Interstitial Cells of Cajal/metabolism
Czasopismo naukowe
Tytuł :
Clinical efficacy comparison of avapritinib with other tyrosine kinase inhibitors in gastrointestinal stromal tumors with PDGFRA D842V mutation: a retrospective analysis of clinical trial and real-world data.
Autorzy :
von Mehren M; Department of Hematology/Oncology, Fox Chase Cancer Center, 333 Cottman Ave, Philadelphia, PA, 19111, USA. .
Heinrich MC; Division of Hematology and Medical Oncology, Portland VA Health Care System and Oregon Health & Science University, Knight Cancer Institute, Portland, OR, USA.
Shi H; Blueprint Medicines Corporation, Cambridge, MA, USA.
Iannazzo S; Blueprint Medicines Corporation, Cambridge, MA, USA.
Mankoski R; Blueprint Medicines Corporation, Cambridge, MA, USA.
Dimitrijević S; Blueprint Medicines Corporation, Cambridge, MA, USA.
Hoehn G; Blueprint Medicines Corporation, Cambridge, MA, USA.
Chiroli S; Blueprint Medicines Corporation, Cambridge, MA, USA.
George S; Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
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Źródło :
BMC cancer [BMC Cancer] 2021 Mar 19; Vol. 21 (1), pp. 291. Date of Electronic Publication: 2021 Mar 19.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Gastrointestinal Stromal Tumors/*drug therapy
Protein Kinase Inhibitors/*administration & dosage
Pyrazoles/*administration & dosage
Pyrroles/*administration & dosage
Receptor, Platelet-Derived Growth Factor alpha/*genetics
Triazines/*administration & dosage
Clinical Trials, Phase I as Topic ; Female ; Gastrointestinal Stromal Tumors/genetics ; Gastrointestinal Stromal Tumors/mortality ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Progression-Free Survival ; Protein Kinase Inhibitors/adverse effects ; Pyrazoles/adverse effects ; Pyrroles/adverse effects ; Receptor, Platelet-Derived Growth Factor alpha/antagonists & inhibitors ; Retrospective Studies ; Triazines/adverse effects
Czasopismo naukowe
Tytuł :
Multiple cell types contribute to the atherosclerotic lesion fibrous cap by PDGFRβ and bioenergetic mechanisms.
Autorzy :
Newman AAC; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.; Cardiovascular Research Center, New York University Langone Medical Center, NY, New York, USA.; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Serbulea V; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.
Baylis RA; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Shankman LS; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.
Bradley X; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.
Alencar GF; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Owsiany K; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Deaton RA; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.
Karnewar S; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.
Shamsuzzaman S; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.
Salamon A; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Reddy MS; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.
Guo L; CVPath Institute, Gaithersburg, MD, USA.
Finn A; CVPath Institute, Gaithersburg, MD, USA.
Virmani R; CVPath Institute, Gaithersburg, MD, USA.
Cherepanova OA; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA.; Cardiovascular and Metabolic Sciences Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Owens GK; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA. .
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Źródło :
Nature metabolism [Nat Metab] 2021 Feb; Vol. 3 (2), pp. 166-181. Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Energy Metabolism/*genetics
Plaque, Atherosclerotic/*pathology
Receptor, Platelet-Derived Growth Factor beta/*genetics
Actins/metabolism ; Animals ; Apolipoproteins E/genetics ; Brachial Artery/pathology ; Diet, Western ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Epithelial-Mesenchymal Transition ; Female ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Humans ; Macrophages/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Myocytes, Smooth Muscle/pathology ; Plaque, Atherosclerotic/metabolism ; Receptor, Platelet-Derived Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł :
Localized inhibition of platelets and platelet derived growth factor by a matrix targeted glycan mimetic significantly attenuates liver fibrosis.
Autorzy :
Kabra H; Symic Bio, USA.
Walimbe T; Symic Bio, USA; University of California, Davis, USA.
Stuart K; Symic Bio, USA.
Indey C; Symic Bio, USA.
Jalgaonkar S; Symic Bio, USA.
Ikwa E; Symic Bio, USA.
Skurnac T; Symic Bio, USA.
Chen J; Symic Bio, USA.
Woolley A; Symic Bio, USA.
Snead NM; Symic Bio, USA.
Bachtell N; Symic Bio, USA.
Leeming DJ; Nordic Biosciences, Biomarker Development, Herlev, Denmark.
Karsdal M; Nordic Biosciences, Biomarker Development, Herlev, Denmark.
Prestwich G; Symic Bio, USA; Washington State University Health Sciences Spokane, USA.
Panitch A; Symic Bio, USA; University of California, Davis, USA. Electronic address: .
Paderi J; Symic Bio, USA.
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Źródło :
Biomaterials [Biomaterials] 2021 Feb; Vol. 269, pp. 120538. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Liver Cirrhosis*/drug therapy
Liver Cirrhosis*/pathology
Platelet-Derived Growth Factor*
Animals ; Blood Platelets ; Hepatic Stellate Cells/pathology ; Liver/pathology ; Mice ; Polysaccharides
Czasopismo naukowe
Tytuł :
Neuropilin-1 directs PDGFRα-entry into lung fibroblasts and signaling from very early endosomes.
Autorzy :
McGowan SE; Department of Veterans Affairs Research Service and Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa.
McCoy DM; Department of Veterans Affairs Research Service and Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Feb 01; Vol. 320 (2), pp. L179-L192. Date of Electronic Publication: 2020 Nov 11.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Signal Transduction*
Endosomes/*metabolism
Fibroblasts/*metabolism
Lung/*metabolism
Neuropilin-1/*metabolism
Receptor, Platelet-Derived Growth Factor beta/*metabolism
Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Endosomes/genetics ; Fibroblasts/cytology ; Lung/cytology ; Mice ; Mice, Knockout ; Neuropilin-1/genetics ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Receptor, Platelet-Derived Growth Factor beta/genetics
Czasopismo naukowe
Tytuł :
PDGF Receptor Alpha Signaling Is Key for Müller Cell Homeostasis Functions.
Autorzy :
Díaz-Lezama N; Department of Physiological Genomics, Biomedical Center, Ludwig-Maximilians-Universität München, D-82152 Planegg-Martinsried, Germany.
Wolf A; Laboratory for Experimental Immunology of the Eye, Department of Ophthalmology, Faculty of Medicine and University Hospital Cologne, University of Cologne, D-50931 Cologne, Germany.
Koch S; Department of Physiological Genomics, Biomedical Center, Ludwig-Maximilians-Universität München, D-82152 Planegg-Martinsried, Germany.
Pfaller AM; Department of Physiological Genomics, Biomedical Center, Ludwig-Maximilians-Universität München, D-82152 Planegg-Martinsried, Germany.
Biber J; Department of Physiological Genomics, Biomedical Center, Ludwig-Maximilians-Universität München, D-82152 Planegg-Martinsried, Germany.
Guillonneau X; Institut de la Vision, INSERM, CNRS, Sorbonne Université, F-75012 Paris, France.
Langmann T; Laboratory for Experimental Immunology of the Eye, Department of Ophthalmology, Faculty of Medicine and University Hospital Cologne, University of Cologne, D-50931 Cologne, Germany.
Grosche A; Department of Physiological Genomics, Biomedical Center, Ludwig-Maximilians-Universität München, D-82152 Planegg-Martinsried, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 25; Vol. 22 (3). Date of Electronic Publication: 2021 Jan 25.
Typ publikacji :
Journal Article
MeSH Terms :
Homeostasis*
Signal Transduction*
Ependymoglial Cells/*metabolism
Receptor, Platelet-Derived Growth Factor alpha/*metabolism
Animals ; Biomarkers ; Choroidal Neovascularization/etiology ; Choroidal Neovascularization/metabolism ; Choroidal Neovascularization/pathology ; Disease Models, Animal ; Fluorescent Antibody Technique ; Gene Expression ; Gene Knockout Techniques ; Gliosis/etiology ; Gliosis/metabolism ; Gliosis/pathology ; Mice ; Mice, Knockout ; Neuroglia/metabolism ; Organ Specificity/genetics ; Receptor, Platelet-Derived Growth Factor alpha/genetics ; Retina/metabolism ; Retina/pathology
Czasopismo naukowe
Tytuł :
Role of platelet-derived growth factor in type II diabetes mellitus and its complications.
Autorzy :
Shen S; BGI Genomics, BGI-Shenzhen, Shenzhen, China.; Diabetes Research Center, Medical School of Ningbo University, Ningbo, China.
Wang F; Diabetes Research Center, Medical School of Ningbo University, Ningbo, China.
Fernandez A; Deanery of Biomedical Sciences, The University of Edinburgh, Edinburgh, UK.
Hu W; BGI Genomics, BGI-Shenzhen, Shenzhen, China.
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Źródło :
Diabetes & vascular disease research [Diab Vasc Dis Res] 2020 Jul-Aug; Vol. 17 (7), pp. 1479164120942119.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Diabetes Complications/*metabolism
Diabetes Mellitus, Type 2/*metabolism
Platelet-Derived Growth Factor/*metabolism
Receptors, Platelet-Derived Growth Factor/*metabolism
Animals ; Diabetes Complications/diagnosis ; Diabetes Complications/drug therapy ; Diabetes Complications/etiology ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/drug therapy ; Humans ; Hypoglycemic Agents/therapeutic use ; Platelet-Derived Growth Factor/antagonists & inhibitors ; Platelet-Derived Growth Factor/therapeutic use ; Receptors, Platelet-Derived Growth Factor/antagonists & inhibitors ; Signal Transduction
Czasopismo naukowe
Tytuł :
The role of bone-derived PDGF-AA in age-related pancreatic β cell proliferation and function.
Autorzy :
Liu X; Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Zhang F; Department of Orthopaedics, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518707, China.
Chai Y; Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Wang L; Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address: .
Yu B; Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Mar 26; Vol. 524 (1), pp. 22-27. Date of Electronic Publication: 2020 Jan 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation/*drug effects
Diabetes Mellitus, Type 2/*metabolism
Insulin Secretion/*drug effects
Insulin-Secreting Cells/*metabolism
Platelet-Derived Growth Factor/*metabolism
Age Factors ; Animals ; Bone and Bones/cytology ; Bone and Bones/metabolism ; Humans ; Mice ; Mice, Inbred C57BL ; Models, Animal ; Osteoblasts/cytology ; Osteoblasts/metabolism ; Receptors, Platelet-Derived Growth Factor/metabolism ; Signal Transduction ; Transplants
Czasopismo naukowe
Tytuł :
Thymosinβ4 alleviates cholestatic liver fibrosis in mice through downregulating PDGF/PDGFR and TGFβ/Smad pathways.
Autorzy :
Chen C; Teaching and Research Centre, Faculty of Medicine, Xinyang Vocational and Technical College, Xinyang, China.
Li X; Department of Biochemistry and Molecular Biology, School of Basic Medical Science, Tianjin Medical University, Tianjin, China. Electronic address: .
Wang L; Department of Respiratory Medicine, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
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Źródło :
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver [Dig Liver Dis] 2020 Mar; Vol. 52 (3), pp. 324-330. Date of Electronic Publication: 2019 Sep 19.
Typ publikacji :
Journal Article
MeSH Terms :
Liver/*pathology
Liver Cirrhosis/*prevention & control
Receptor, Platelet-Derived Growth Factor beta/*metabolism
Thymosin/*pharmacology
Transforming Growth Factor beta/*metabolism
Animals ; Collagen Type I/metabolism ; Cytokines/metabolism ; Down-Regulation/drug effects ; Hepatic Stellate Cells/drug effects ; Hepatic Stellate Cells/metabolism ; Male ; Mice ; Mice, Inbred BALB C ; Platelet-Derived Growth Factor/metabolism ; Signal Transduction/drug effects ; Smad Proteins/metabolism
Czasopismo naukowe
Tytuł :
Blocking PDGF-CC signaling ameliorates multiple sclerosis-like neuroinflammation by inhibiting disruption of the blood-brain barrier.
Autorzy :
Zeitelhofer M; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden. .
Adzemovic MZ; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden.; Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Moessinger C; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden.
Stefanitsch C; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden.
Strell C; Department of Immunology, Genetics and Pathology, Uppsala University, 75185, Uppsala, Sweden.
Muhl L; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden.
Brundin L; Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Fredriksson L; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden.
Olsson T; Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Eriksson U; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden.
Nilsson I; Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden. .
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Źródło :
Scientific reports [Sci Rep] 2020 Dec 24; Vol. 10 (1), pp. 22383. Date of Electronic Publication: 2020 Dec 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Neutralizing/*pharmacology
Blood-Brain Barrier/*immunology
Encephalomyelitis, Autoimmune, Experimental/*immunology
Lymphokines/*antagonists & inhibitors
Multiple Sclerosis/*immunology
Platelet-Derived Growth Factor/*antagonists & inhibitors
Signal Transduction/*drug effects
Animals ; Blood-Brain Barrier/pathology ; Down-Regulation/drug effects ; Down-Regulation/immunology ; Encephalomyelitis, Autoimmune, Experimental/drug therapy ; Encephalomyelitis, Autoimmune, Experimental/genetics ; Encephalomyelitis, Autoimmune, Experimental/pathology ; Inflammation/drug therapy ; Inflammation/genetics ; Inflammation/immunology ; Inflammation/pathology ; Interleukin-1alpha/genetics ; Interleukin-1alpha/immunology ; Lymphokines/genetics ; Lymphokines/immunology ; Mice ; Mice, Transgenic ; Multiple Sclerosis/drug therapy ; Multiple Sclerosis/genetics ; Multiple Sclerosis/pathology ; Platelet-Derived Growth Factor/genetics ; Platelet-Derived Growth Factor/immunology ; Signal Transduction/genetics ; Signal Transduction/immunology ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology
Czasopismo naukowe
Tytuł :
Molecular Modeling Study of c-KIT/PDGFRα Dual Inhibitors for the Treatment of Gastrointestinal Stromal Tumors.
Autorzy :
Keretsu S; Department of Biomedical Sciences, College of Medicine, Chosun University, Gwangju 501-759, Korea.
Ghosh S; Department of Biomedical Sciences, College of Medicine, Chosun University, Gwangju 501-759, Korea.
Cho SJ; Department of Biomedical Sciences, College of Medicine, Chosun University, Gwangju 501-759, Korea.; Department of Cellular Molecular Medicine, College of Medicine, Chosun University, Gwangju 501-759, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 03; Vol. 21 (21). Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Molecular*
Gastrointestinal Neoplasms/*drug therapy
Gastrointestinal Stromal Tumors/*drug therapy
Protein Kinase Inhibitors/*isolation & purification
Proto-Oncogene Proteins c-kit/*antagonists & inhibitors
Receptor, Platelet-Derived Growth Factor alpha/*antagonists & inhibitors
Amino Acid Substitution ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/isolation & purification ; Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/therapeutic use ; Binding Sites ; Drug Screening Assays, Antitumor/methods ; Humans ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Mutant Proteins/chemistry ; Mutant Proteins/genetics ; Mutant Proteins/metabolism ; Protein Kinase Inhibitors/chemistry ; Protein Kinase Inhibitors/pharmacokinetics ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins c-kit/chemistry ; Proto-Oncogene Proteins c-kit/genetics ; Proto-Oncogene Proteins c-kit/metabolism ; Pyrazoles/chemistry ; Pyridines/chemistry ; Quantitative Structure-Activity Relationship ; Receptor, Platelet-Derived Growth Factor alpha/chemistry ; Receptor, Platelet-Derived Growth Factor alpha/genetics ; Receptor, Platelet-Derived Growth Factor alpha/metabolism
Czasopismo naukowe
Tytuł :
Epidemiology, clinical picture and long-term outcomes of FIP1L1-PDGFRA-positive myeloid neoplasm with eosinophilia: Data from 151 patients.
Autorzy :
Rohmer J; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.; Department of Internal Medicine, Hôpital Foch, Suresnes, France.
Couteau-Chardon A; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.; Department of Intensive Care medicine, Centre Hospitalier Annecy Genevois, Saint-Julien-en-Genevois, France.
Trichereau J; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.; Clinical Research Department, Hôpital Foch, Suresnes, France.
Panel K; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.; Clinical Research Department, Hôpital Foch, Suresnes, France.
Gesquiere C; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.
Ben Abdelali R; Pole Hématologie et Oncologie, Laboratoire CERBA, Saint-Ouen-l'Aumône, France.
Bidet A; Laboratory of Hematology, CHU de Bordeaux, Pessac, France.
Bladé JS; Department of Oncology, Sainte-Anne Military Teaching Hospital, Toulon, France.
Cayuela JM; Laboratory of Hematology, Saint-Louis Hospital, University of Paris, Paris, France.
Cony-Makhoul P; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.; Hematology Department, CH Annecy Genevois, Annecy, France.
Cottin V; National Coordinating Reference Center for Rare Pulmonary Diseases, Louis Pradel Hospital, Lyon, France.; Hospices Civils de Lyon, UMR754, University Claude Bernard Lyon 1, Lyon, France.
Delabesse E; Laboratory of Hematology, Institut Universitaire du Cancer de Toulouse Oncopole, CHU de Toulouse, Toulouse, France.
Ebbo M; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.; Aix Marseille University, Department of Internal Medicine, Hôpital de la Timone, AP-HM, CNRS, INSERM, CIML, Marseille, France.
Fain O; Department of Internal Medicine, CHU Saint Antoine, Paris, France.
Flandrin P; Laboratory of Hematology, Hôpital Nord, CHU de Saint-Étienne, Saint-Étienne, France.
Galicier L; Department of Clinical Immunology, Saint Louis hospital, Paris, France.
Godon C; Laboratoire de cytogénétique hématologique, CHU de Nantes, Nantes, France.
Grardel N; Laboratory of Hematology, CHU de Lille, Lille, France.
Guffroy A; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.; Department of Clinical Immunology and Internal Medicine, National Reference Center for Systemic Autoimmune Diseases (RESO), Tertiary Center for Primary Immunodeficiency, Strasbourg University Hospital, Strasbourg, France.
Hamidou M; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.; Department of Internal Medicine, CHU de Nantes, Nantes, France.
Hunault M; CRCINA CHU d'Angers, Angers, France.
Lengline E; Department of Hematology, Saint Louis hospital, Paris, France.
Lhomme F; Department of Hematology, CHU Pontchaillou, Rennes, France.
Lhermitte L; University of Paris, Institut National de Recherche Médicale U1151, Laboratory of Onco-Hematology, Hôpital Necker Enfants-Malades, Paris, France.
Machelart I; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.; Department of Internal Medicine, CHU de Bordeaux, Bordeaux, France.
Mauvieux L; Université de Strasbourg, INSERM U1113 Interface de Recherche Fondamentale et Appliquée en Cancérologie, Laboratoire d'hématologie du CHRU Strasbourg, Faculté de Médecine de Strasbourg, Strasbourg, France.
Mohr C; Service d'Hématologie Oncologie, CHU, Groupe Hospitalier Sud Réunion, Saint Pierre, Reunion, France.
Mozicconacci MJ; Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille, Biopathologie, Marseille, France.
Naguib D; Laboratory of Hematology, CHU Caen, Caen, France.
Nicolini FE; Department of Hematology, INSERM U 1052, CRCL, Centre Léon Bérard, Lyon, France.
Rey J; Department of Hematology, Institut Paoli-Calmettes, Marseille, France.
Rousselot P; Hematology Department, Versailles André Mignot Hospital, University Paris-Saclay, Le Chesnay, France.
Tavitian S; Service d'Hématologie, Institut Universitaire du Cancer de Toulouse-Oncopole, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.
Terriou L; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.; Université de Lille, CHU Lille, Département de Médecine Interne et Immunologie Clinique, Centre de Référence des Maladies Auto-immunes Systémiques Rares du Nord et Nord-Ouest de France (CeRAINO), Lille, France.
Lefèvre G; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.; Université de Lille, CHU Lille, Département de Médecine Interne et Immunologie Clinique, Centre de Référence des Maladies Auto-immunes Systémiques Rares du Nord et Nord-Ouest de France (CeRAINO), Lille, France.
Preudhomme C; Laboratory of Hematology, CHU de Lille, Lille, France.
Kahn JE; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.; Université Paris-Saclay, Department of Internal Medicine, Ambroise Paré hospital, Boulogne Billancourt Cedex, France.
Groh M; National Reference Center for Hypereosinophilic syndromes (CEREO), Suresnes, France.; Department of Internal Medicine, Hôpital Foch, Suresnes, France.
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Corporate Authors :
CEREO and GBMHM collaborators
Źródło :
American journal of hematology [Am J Hematol] 2020 Nov; Vol. 95 (11), pp. 1314-1323. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Clinical Trial; Journal Article; Multicenter Study
MeSH Terms :
Eosinophilia*/blood
Eosinophilia*/drug therapy
Eosinophilia*/genetics
Eosinophilia*/mortality
Hematologic Neoplasms*/blood
Hematologic Neoplasms*/drug therapy
Hematologic Neoplasms*/genetics
Hematologic Neoplasms*/mortality
Myeloproliferative Disorders*/blood
Myeloproliferative Disorders*/drug therapy
Myeloproliferative Disorders*/genetics
Myeloproliferative Disorders*/mortality
Oncogene Proteins, Fusion*/blood
Oncogene Proteins, Fusion*/genetics
Receptor, Platelet-Derived Growth Factor alpha*/blood
Receptor, Platelet-Derived Growth Factor alpha*/genetics
mRNA Cleavage and Polyadenylation Factors*/blood
mRNA Cleavage and Polyadenylation Factors*/genetics
Adrenal Cortex Hormones/*administration & dosage
Adult ; Disease-Free Survival ; Female ; France/epidemiology ; Humans ; Incidence ; Male ; Middle Aged ; Retrospective Studies ; Survival Rate ; Tryptases/blood ; Vitamin B 12/blood
Czasopismo naukowe

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