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Tytuł :
Lipopolysaccharide influences the plasma and brain pharmacokinetics of subcutaneously-administered HsTX1[R14A], a K V 1.3-blocking peptide.
Autorzy :
Reddiar SB; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Jin L; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Wai DCC; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Csoti A; Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, Hungary.
Panyi G; Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, Hungary.
Norton RS; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia; ARC Centre for Fragment-Based Design, Monash University, Parkville, Victoria, Australia.
Nicolazzo JA; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia. Electronic address: .
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Źródło :
Toxicon : official journal of the International Society on Toxinology [Toxicon] 2021 May; Vol. 195, pp. 29-36. Date of Electronic Publication: 2021 Mar 06.
Typ publikacji :
Journal Article
MeSH Terms :
Kv1.3 Potassium Channel*/metabolism
Lipopolysaccharides/*toxicity
Scorpion Venoms/*toxicity
Animals ; Brain/metabolism ; Chromatography, Liquid ; Mice ; Mice, Inbred C57BL ; Peptides ; Plasma ; Potassium Channel Blockers ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Involvement of salicylic acid in the response to potassium deficiency revealed by metabolomics.
Autorzy :
Cui J; Research School of Biology, ANU College of Science, Australian National University, 2601, Canberra, ACT, Australia.
Nieves-Cordones M; Departamento de Nutrición Vegetal, Centro de Edafología y Biología Aplicada del Segura, Consejo Superior de Investigaciones Científicas, Campus de Espinardo, 30100, Murcia, Spain.
Rubio F; Departamento de Nutrición Vegetal, Centro de Edafología y Biología Aplicada del Segura, Consejo Superior de Investigaciones Científicas, Campus de Espinardo, 30100, Murcia, Spain.
Tcherkez G; Research School of Biology, ANU College of Science, Australian National University, 2601, Canberra, ACT, Australia; Institut de Recherche en Horticulture et Semences, Université d'Angers, INRAe, 42 rue Georges Morel, 49070, Beaucouzé, France. Electronic address: .
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Źródło :
Plant physiology and biochemistry : PPB [Plant Physiol Biochem] 2021 Jun; Vol. 163, pp. 201-204. Date of Electronic Publication: 2021 Apr 06.
Typ publikacji :
Journal Article
MeSH Terms :
Arabidopsis Proteins*/metabolism
Potassium Deficiency*
Kinetics ; Metabolomics ; Potassium/metabolism ; Potassium Channels/metabolism ; Protein-Serine-Threonine Kinases/metabolism ; Salicylic Acid
Czasopismo naukowe
Tytuł :
Toxicity and physiological actions of biflavones on potassium current in insect neuronal cells.
Autorzy :
Ren Y; Key Laboratory of Coarse Cereal Processing of Ministry of Agriculture and Rural Affairs, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, Sichuan, China; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan, China.
Li Q; Key Laboratory of Coarse Cereal Processing of Ministry of Agriculture and Rural Affairs, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, Sichuan, China; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan, China.
Lu L; Key Laboratory of Coarse Cereal Processing of Ministry of Agriculture and Rural Affairs, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, Sichuan, China; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan, China.
Jin H; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan, China.
Tao K; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan, China. Electronic address: .
Hou T; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan, China. Electronic address: .
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Źródło :
Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2021 Jan; Vol. 171, pp. 104735. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article
MeSH Terms :
Potassium*
Potassium Channels, Voltage-Gated*
Animals ; Insecta ; Patch-Clamp Techniques ; Potassium Channels
Czasopismo naukowe
Tytuł :
Physiological roles of heteromerization: focus on the two-pore domain potassium channels.
Autorzy :
Khoubza L; Université côte d'Azur, IPMC CNRS UMR7275, Laboratory of Excellence ICST, 660 route des Lucioles 06650 Valbonne, France.
Chatelain FC; Université côte d'Azur, IPMC CNRS UMR7275, Laboratory of Excellence ICST, 660 route des Lucioles 06650 Valbonne, France.
Feliciangeli S; Université côte d'Azur, IPMC CNRS UMR7275, Laboratory of Excellence ICST, 660 route des Lucioles 06650 Valbonne, France.; Inserm, 101 rue de Tolbiac, 75013, Paris, France.
Lesage F; Université côte d'Azur, IPMC CNRS UMR7275, Laboratory of Excellence ICST, 660 route des Lucioles 06650 Valbonne, France.; Inserm, 101 rue de Tolbiac, 75013, Paris, France.
Bichet D; Université côte d'Azur, IPMC CNRS UMR7275, Laboratory of Excellence ICST, 660 route des Lucioles 06650 Valbonne, France.
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Źródło :
The Journal of physiology [J Physiol] 2021 Feb; Vol. 599 (4), pp. 1041-1055. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Potassium Channels, Tandem Pore Domain*/genetics
Potassium Channels, Tandem Pore Domain*/metabolism
Neurons/metabolism ; Potassium ; Protein Transport ; Signal Transduction
Czasopismo naukowe
Tytuł :
Potassium voltage-gated channel subfamily D member 2 induces an aggressive phenotype in lung adenocarcinoma.
Autorzy :
Lu X; Department of Emergency, Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Li K; Department of Oncology, Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yang J; Department of General Practice, Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
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Źródło :
Neoplasma [Neoplasma] 2021 Jan; Vol. 68 (1), pp. 135-143. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma of Lung*/genetics
Adenocarcinoma of Lung*/metabolism
Adenocarcinoma of Lung*/pathology
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Lung Neoplasms*/pathology
Shal Potassium Channels*/genetics
Shal Potassium Channels*/metabolism
Cell Movement ; Cell Proliferation/physiology ; Humans ; Phenotype ; Potassium
Czasopismo naukowe
Tytuł :
Cutting out the fat: Site-specific deacylation of an ion channel.
Autorzy :
Del Rivero Morfin PJ; Department of Physiology and Cellular Biophysics, Columbia University, New York, New York, USA.
Ben-Johny M; Department of Physiology and Cellular Biophysics, Columbia University, New York, New York, USA. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Dec 04; Vol. 295 (49), pp. 16497-16498.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Ion Channels*/genetics
Large-Conductance Calcium-Activated Potassium Channels*/metabolism
Acylation ; Mutation ; Potassium
Czasopismo naukowe
Tytuł :
Potassium deficiency decreases the capacity for urea synthesis and markedly increases ammonia in rats.
Autorzy :
Mikkelsen ACD; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Thomsen KL; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.; UCL Institute of Liver and Digestive Health, University College London, London, United Kingdom.
Vilstrup H; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Aamann L; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Jones H; UCL Institute of Liver and Digestive Health, University College London, London, United Kingdom.
Mookerjee RP; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.; UCL Institute of Liver and Digestive Health, University College London, London, United Kingdom.
Hamilton-Dutoit S; Department of Pathology, Aarhus University Hospital, Aarhus, Denmark.
Frystyk J; Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.
Aagaard NK; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
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Źródło :
American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2021 Apr 01; Vol. 320 (4), pp. G474-G483. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ammonia/*blood
Hyperammonemia/*etiology
Hypokalemia/*etiology
Potassium/*blood
Potassium Deficiency/*complications
Urea/*blood
Animals ; Disease Models, Animal ; Female ; Gene Expression Regulation, Enzymologic ; Hyperammonemia/blood ; Hyperammonemia/genetics ; Hypokalemia/blood ; Hypokalemia/genetics ; Kidney/metabolism ; Liver/metabolism ; Muscle, Skeletal/metabolism ; Potassium Deficiency/blood ; Potassium, Dietary/administration & dosage ; Potassium, Dietary/metabolism ; Rats, Wistar
Czasopismo naukowe
Tytuł :
COVID-19 Drugs Chloroquine and Hydroxychloroquine, but Not Azithromycin and Remdesivir, Block hERG Potassium Channels.
Autorzy :
Szendrey M; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Guo J; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Li W; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Yang T; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Zhang S; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada .
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Źródło :
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2021 May; Vol. 377 (2), pp. 265-272. Date of Electronic Publication: 2021 Mar 05.
Typ publikacji :
Journal Article
MeSH Terms :
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Azithromycin/*pharmacology
COVID-19/*drug therapy
Chloroquine/*pharmacology
ERG1 Potassium Channel/*antagonists & inhibitors
Hydroxychloroquine/*pharmacology
Adenosine Monophosphate/pharmacology ; Adenosine Monophosphate/therapeutic use ; Alanine/pharmacology ; Alanine/therapeutic use ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Antimalarials/pharmacology ; Antimalarials/therapeutic use ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Azithromycin/therapeutic use ; COVID-19/metabolism ; Chloroquine/therapeutic use ; Dose-Response Relationship, Drug ; ERG1 Potassium Channel/metabolism ; HEK293 Cells ; Humans ; Hydroxychloroquine/therapeutic use ; Potassium Channel Blockers/pharmacology ; Potassium Channel Blockers/therapeutic use
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Neuromodulation of Astrocytic K Clearance.
Autorzy :
Bellot-Saez A; School of Medicine, Western Sydney University, Campbelltown, NSW 2560, Australia.
Stevenson R; School of Medicine, Western Sydney University, Campbelltown, NSW 2560, Australia.
Kékesi O; School of Medicine, Western Sydney University, Campbelltown, NSW 2560, Australia.
Samokhina E; School of Medicine, Western Sydney University, Campbelltown, NSW 2560, Australia.
Ben-Abu Y; Projects and Physics Section, Sapir Academic College, D.N. Hof Ashkelon, Sderot 79165, Israel.
Morley JW; School of Medicine, Western Sydney University, Campbelltown, NSW 2560, Australia.
Buskila Y; School of Medicine, Western Sydney University, Campbelltown, NSW 2560, Australia.; International Centre for Neuromorphic Systems, The MARCS Institute, Western Sydney University, Penrith, NSW 2751, Australia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 03; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*metabolism
Neurotransmitter Agents/*metabolism
Potassium/*metabolism
Animals ; Gap Junctions/metabolism ; Homeostasis/physiology ; Mice ; Mice, Inbred C57BL ; Neurons/metabolism ; Sodium-Potassium-Exchanging ATPase/metabolism
Czasopismo naukowe
Tytuł :
Effect of Dynamic and Static Load on the Concentration of Myokines in the Blood Plasma and Content of Sodium and Potassium in Mouse Skeletal Muscles.
Autorzy :
Kironenko TA; National Research Tomsk State University, Tomsk, 634050, Russia.
Milovanova KG; National Research Tomsk State University, Tomsk, 634050, Russia.
Zakharova AN; National Research Tomsk State University, Tomsk, 634050, Russia.
Sidorenko SV; Faculty of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.
Klimanova EA; National Research Tomsk State University, Tomsk, 634050, Russia. .; Faculty of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.
Dyakova EY; National Research Tomsk State University, Tomsk, 634050, Russia.
Orlova AA; National Research Tomsk State University, Tomsk, 634050, Russia.
Negodenko ES; National Research Tomsk State University, Tomsk, 634050, Russia.
Kalinnikova YG; National Research Tomsk State University, Tomsk, 634050, Russia.
Orlov SN; National Research Tomsk State University, Tomsk, 634050, Russia.; Faculty of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.
Kapilevich LV; National Research Tomsk State University, Tomsk, 634050, Russia. .
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Źródło :
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2021 Mar; Vol. 86 (3), pp. 370-381.
Typ publikacji :
Journal Article
MeSH Terms :
Physical Conditioning, Animal*
Cytokines/*blood
Muscle, Skeletal/*physiology
Sodium-Potassium-Exchanging ATPase/*metabolism
Animals ; Cations, Monovalent ; Interleukin-15/blood ; Interleukin-6/blood ; Interleukin-8/blood ; Male ; Mice ; Mice, Inbred C57BL ; Muscle, Skeletal/chemistry ; Muscle, Skeletal/enzymology ; Muscle, Skeletal/metabolism ; Plasma/metabolism ; Potassium/analysis ; Potassium/chemistry ; Sodium/analysis ; Sodium/chemistry
Czasopismo naukowe
Tytuł :
A rapid solubility assay of protein domain misfolding for pathogenicity assessment of rare DNA sequence variants.
Autorzy :
Anderson CL; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA. .; Cellular and Molecular Arrhythmias Research Program, University of Wisconsin-Madison, Madison, WI, USA. .
Routes TC; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Cellular and Molecular Arrhythmias Research Program, University of Wisconsin-Madison, Madison, WI, USA.
Eckhardt LL; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Cellular and Molecular Arrhythmias Research Program, University of Wisconsin-Madison, Madison, WI, USA.
Delisle BP; Department of Physiology, University of Kentucky-Lexington, Lexington, KY, USA.
January CT; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Cellular and Molecular Arrhythmias Research Program, University of Wisconsin-Madison, Madison, WI, USA.
Kamp TJ; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA. .; Cellular and Molecular Arrhythmias Research Program, University of Wisconsin-Madison, Madison, WI, USA. .; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, USA. .
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Źródło :
Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2020 Oct; Vol. 22 (10), pp. 1642-1652. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Escherichia coli*/metabolism
Ether-A-Go-Go Potassium Channels*/genetics
Ether-A-Go-Go Potassium Channels*/metabolism
Base Sequence ; ERG1 Potassium Channel ; Humans ; Protein Domains ; Solubility ; Virulence
Czasopismo naukowe
Tytuł :
Intracellular fluoride influences TASK mediated currents in human T cells.
Autorzy :
Herrmann AM; Department of Neurology with Institute of Translational Neurology, Münster University Hospital, Münster, Germany. Electronic address: .
Cerina M; Department of Neurology with Institute of Translational Neurology, Münster University Hospital, Münster, Germany.
Bittner S; Department of Neurology, University of Mainz, Mainz, Germany.
Meuth SG; Department of Neurology with Institute of Translational Neurology, Münster University Hospital, Münster, Germany.
Budde T; Institute of Physiology I, Westfälische-Wilhems Universität Münster, Münster, Germany. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2020 Dec; Vol. 487, pp. 112875. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fluorides/*pharmacology
Membrane Potentials/*drug effects
Potassium Channels, Tandem Pore Domain/*metabolism
Potassium Compounds/*pharmacology
T-Lymphocytes/*drug effects
Cells, Cultured ; Fluorides/metabolism ; Humans ; Kv1.3 Potassium Channel/drug effects ; Kv1.3 Potassium Channel/metabolism ; Magnesium Chloride/metabolism ; Magnesium Chloride/pharmacology ; Patch-Clamp Techniques ; Potassium Channel Blockers/pharmacology ; Potassium Channels, Tandem Pore Domain/drug effects ; Potassium Compounds/metabolism ; T-Lymphocytes/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
Cryo-EM analysis of PIP 2 regulation in mammalian GIRK channels.
Autorzy :
Niu Y; Laboratory of Molecular Neurobiology and Biophysics, The Rockefeller University, Howard Hughes Medical Institute, New York, United States.
Tao X; Laboratory of Molecular Neurobiology and Biophysics, The Rockefeller University, Howard Hughes Medical Institute, New York, United States.
Touhara KK; Laboratory of Molecular Neurobiology and Biophysics, The Rockefeller University, Howard Hughes Medical Institute, New York, United States.
MacKinnon R; Laboratory of Molecular Neurobiology and Biophysics, The Rockefeller University, Howard Hughes Medical Institute, New York, United States.
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Źródło :
ELife [Elife] 2020 Aug 26; Vol. 9. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
G Protein-Coupled Inwardly-Rectifying Potassium Channels*/chemistry
G Protein-Coupled Inwardly-Rectifying Potassium Channels*/metabolism
Phosphatidylinositol 4,5-Diphosphate*/chemistry
Phosphatidylinositol 4,5-Diphosphate*/metabolism
Animals ; Cryoelectron Microscopy ; Humans ; Mice ; Neurons/chemistry ; Potassium Channels, Inwardly Rectifying/chemistry ; Potassium Channels, Inwardly Rectifying/metabolism ; Protein Binding ; Protein Conformation
Czasopismo naukowe
Tytuł :
A role for TASK2 channels in the human immunological synapse.
Autorzy :
Fernández-Orth J; Department of Neurology, Westfälische Wilhelms-Universität, Münster, Germany.
Rolfes L; Department of Neurology, Westfälische Wilhelms-Universität, Münster, Germany.
Gola L; Department of Neurology, Westfälische Wilhelms-Universität, Münster, Germany.
Bittner S; Department of Neurology, University Medical Center, Johannes Gutenberg-University, Mainz, Germany.
Andronic J; Department of Biotechnology and Biophysics, Biocenter, Julius-Maximilians-University Würzburg, Würzburg, Germany.
Sukhorukov VL; Department of Biotechnology and Biophysics, Biocenter, Julius-Maximilians-University Würzburg, Würzburg, Germany.
Sisario D; Department of Biotechnology and Biophysics, Biocenter, Julius-Maximilians-University Würzburg, Würzburg, Germany.
Landgraf P; Neural Plasticity and Communication, Institute for Pharmacology and Toxicology, Otto-von-Guericke-University, Magdeburg, Germany.
Dieterich DC; Neural Plasticity and Communication, Institute for Pharmacology and Toxicology, Otto-von-Guericke-University, Magdeburg, Germany.; Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany.
Cerina M; Department of Neurology, Westfälische Wilhelms-Universität, Münster, Germany.
Smalla KH; Special Lab Molecular Biological Techniques, Leibniz Institute for Neurobiology, Magdeburg, Germany.
Kähne T; Institute of Experimental Internal Medicine, Medical Faculty, Otto-von-Guericke-University, Magdeburg, Germany.
Budde T; Institute of Physiology I, Westfälische Wilhelms-Universität, Münster, Germany.
Kovac S; Department of Neurology, Westfälische Wilhelms-Universität, Münster, Germany.
Ruck T; Department of Neurology, Westfälische Wilhelms-Universität, Münster, Germany.
Sauer M; Department of Biotechnology and Biophysics, Biocenter, Julius-Maximilians-University Würzburg, Würzburg, Germany.
Meuth SG; Department of Neurology, Westfälische Wilhelms-Universität, Münster, Germany.
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Źródło :
European journal of immunology [Eur J Immunol] 2021 Feb; Vol. 51 (2), pp. 342-353. Date of Electronic Publication: 2020 Dec 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunological Synapses/*immunology
Potassium Channels, Tandem Pore Domain/*immunology
Animals ; Autoimmune Diseases/immunology ; CD3 Complex/immunology ; Calcium/immunology ; Cell Line, Tumor ; Cell Membrane/immunology ; Cells, Cultured ; Female ; Gene Expression/immunology ; Humans ; Intermediate-Conductance Calcium-Activated Potassium Channels/immunology ; Jurkat Cells ; Kv1.3 Potassium Channel/immunology ; Male ; Mice ; Mice, Inbred C57BL ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł :
Kir4.1 RNA Interference by In Utero Electroporation Fails to Affect Ictogenesis and Reveals a Possible role of Kir4.1 in Corticogenesis.
Autorzy :
Moroni RF; Epilepsy Unit, Fondazione I.R.C.C.S. Istituto Neurologico 'C. Besta', via Celoria 11, 20133 Milan, Italy. Electronic address: .
Regondi MC; Epilepsy Unit, Fondazione I.R.C.C.S. Istituto Neurologico 'C. Besta', via Celoria 11, 20133 Milan, Italy. Electronic address: .
de Curtis M; Epilepsy Unit, Fondazione I.R.C.C.S. Istituto Neurologico 'C. Besta', via Celoria 11, 20133 Milan, Italy. Electronic address: .
Frassoni C; Epilepsy Unit, Fondazione I.R.C.C.S. Istituto Neurologico 'C. Besta', via Celoria 11, 20133 Milan, Italy. Electronic address: .
Librizzi L; Epilepsy Unit, Fondazione I.R.C.C.S. Istituto Neurologico 'C. Besta', via Celoria 11, 20133 Milan, Italy. Electronic address: .
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Źródło :
Neuroscience [Neuroscience] 2020 Aug 10; Vol. 441, pp. 65-76. Date of Electronic Publication: 2020 Jun 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Potassium Channels, Inwardly Rectifying*/genetics
Potassium Channels, Inwardly Rectifying*/metabolism
Animals ; Astrocytes/metabolism ; Electroporation ; Potassium/metabolism ; RNA Interference ; Rats
Czasopismo naukowe
Tytuł :
BK Channels Regulate LPS-induced CCL-2 Release from Human Pulmonary Endothelial Cells.
Autorzy :
Zyrianova T; Department of Pediatrics.
Lopez B; Department of Pediatrics.
Liao A; Department of Pediatrics.
Gu C; Department of Pediatrics.
Wong L; Department of Pediatrics.
Ottolia M; Department of Anesthesiology and Perioperative Medicine, and.
Olcese R; Department of Anesthesiology and Perioperative Medicine, and.; Department of Physiology, University of California Los Angeles, Los Angeles, California.
Schwingshackl A; Department of Pediatrics.
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Źródło :
American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2021 Feb; Vol. 64 (2), pp. 224-234.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Alveolar Epithelial Cells/*metabolism
Chemokine CCL2/*metabolism
Endothelial Cells/*metabolism
Large-Conductance Calcium-Activated Potassium Channels/*metabolism
Lung/*metabolism
A549 Cells ; Acute Lung Injury/chemically induced ; Acute Lung Injury/metabolism ; Alveolar Epithelial Cells/drug effects ; Calcium/metabolism ; Cell Line ; Cell Line, Tumor ; Cytokines/metabolism ; Endothelial Cells/drug effects ; HEK293 Cells ; Humans ; Hyperoxia/chemically induced ; Hyperoxia/metabolism ; Inflammation/chemically induced ; Inflammation/metabolism ; Interleukin-6/metabolism ; Lipopolysaccharides/pharmacology ; Lung/drug effects ; Membrane Potentials/drug effects ; Membrane Potentials/physiology ; Potassium Channels, Tandem Pore Domain/metabolism
Czasopismo naukowe
Tytuł :
Functional Coupling of Slack Channels and P2X3 Receptors Contributes to Neuropathic Pain Processing.
Autorzy :
Lu R; Institut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Metzner K; Institut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Zhou F; Institut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Flauaus C; Institut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Balzulat A; Institut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Engel P; Institut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Petersen J; Institut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
Ehinger R; Pharmakologie, Toxikologie und Klinische Pharmazie, Institut für Pharmazie, Universität Tübingen, 72076 Tübingen, Baden-Württemberg, Germany.
Bausch A; Pharmakologie, Toxikologie und Klinische Pharmazie, Institut für Pharmazie, Universität Tübingen, 72076 Tübingen, Baden-Württemberg, Germany.
Ruth P; Pharmakologie, Toxikologie und Klinische Pharmazie, Institut für Pharmazie, Universität Tübingen, 72076 Tübingen, Baden-Württemberg, Germany.
Lukowski R; Pharmakologie, Toxikologie und Klinische Pharmazie, Institut für Pharmazie, Universität Tübingen, 72076 Tübingen, Baden-Württemberg, Germany.
Schmidtko A; Institut für Pharmakologie und Klinische Pharmazie, Goethe-Universität Frankfurt am Main, 60438 Frankfurt am Main, Hessen, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 02; Vol. 22 (1). Date of Electronic Publication: 2021 Jan 02.
Typ publikacji :
Journal Article
MeSH Terms :
Adenosine Triphosphate/*analogs & derivatives
Calcium/*pharmacology
Nerve Tissue Proteins/*metabolism
Neuralgia/*metabolism
Potassium Channels, Sodium-Activated/*metabolism
Receptors, Purinergic P2X3/*metabolism
Sensory Receptor Cells/*physiology
Adenosine Triphosphate/pharmacology ; Animals ; Behavior Rating Scale ; Ganglia, Spinal/drug effects ; Ganglia, Spinal/physiology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Nerve Tissue Proteins/genetics ; Patch-Clamp Techniques ; Peripheral Nerves/pathology ; Potassium Channels/metabolism ; Potassium Channels/physiology ; Potassium Channels, Sodium-Activated/genetics ; Receptors, Purinergic P2X3/physiology ; Sensory Receptor Cells/drug effects ; Sensory Receptor Cells/metabolism ; Signal Transduction/drug effects ; Signal Transduction/genetics ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Mechanistic insights into volatile anesthetic modulation of K2P channels.
Autorzy :
Wague A; Department of Anesthesiology, Weill Cornell Medical College, New York City, United States.
Joseph TT; Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, United States.
Woll KA; Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, United States.
Bu W; Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, United States.
Vaidya KA; Department of Anesthesiology, Weill Cornell Medical College, New York City, United States.
Bhanu NV; Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.
Garcia BA; Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.
Nimigean CM; Department of Anesthesiology, Weill Cornell Medical College, New York City, United States.; Department of Physiology and Biophysics, Weill Cornell Medical College, New York City, United States.; Department of Biochemistry, Weill Cornell Medical College, New York City, United States.
Eckenhoff RG; Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, United States.
Riegelhaupt PM; Department of Anesthesiology, Weill Cornell Medical College, New York City, United States.
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Źródło :
ELife [Elife] 2020 Dec 21; Vol. 9. Date of Electronic Publication: 2020 Dec 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anesthetics, Inhalation/*pharmacology
Potassium Channels, Tandem Pore Domain/*drug effects
Anesthetics, Inhalation/metabolism ; Animals ; Binding Sites ; Humans ; Isoflurane/pharmacology ; Mice ; Molecular Docking Simulation ; Potassium Channels/drug effects ; Potassium Channels/metabolism ; Potassium Channels, Tandem Pore Domain/metabolism ; Xenopus laevis ; Zebrafish
Czasopismo naukowe
Tytuł :
The Venus flytrap trigger hair-specific potassium channel KDM1 can reestablish the K+ gradient required for hapto-electric signaling.
Autorzy :
Iosip AL; Institute for Molecular Plant Physiology and Biophysics, University of Würzburg, Würzburg, Germany.; Center for Computational and Theoretical Biology, University of Würzburg, Würzburg, Germany.
Böhm J; Institute for Molecular Plant Physiology and Biophysics, University of Würzburg, Würzburg, Germany.
Scherzer S; Institute for Molecular Plant Physiology and Biophysics, University of Würzburg, Würzburg, Germany.
Al-Rasheid KAS; Zoology Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Dreyer I; Center of Bioinformatics, Simulation and Modeling (CBSM), Faculty of Engineering, Universidad de Talca, Talca, Chile.
Schultz J; Center for Computational and Theoretical Biology, University of Würzburg, Würzburg, Germany.
Becker D; Institute for Molecular Plant Physiology and Biophysics, University of Würzburg, Würzburg, Germany.
Kreuzer I; Institute for Molecular Plant Physiology and Biophysics, University of Würzburg, Würzburg, Germany.
Hedrich R; Institute for Molecular Plant Physiology and Biophysics, University of Würzburg, Würzburg, Germany.
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Źródło :
PLoS biology [PLoS Biol] 2020 Dec 09; Vol. 18 (12), pp. e3000964. Date of Electronic Publication: 2020 Dec 09 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Droseraceae/*genetics
Droseraceae/*metabolism
Potassium Channels/*metabolism
Action Potentials/physiology ; Biological Transport ; Electrophysiological Phenomena ; Gene Expression/genetics ; Gene Expression Regulation, Plant/genetics ; Ions ; Mechanoreceptors/metabolism ; Mechanoreceptors/physiology ; Plant Leaves/physiology ; Potassium/metabolism ; Potassium Channels/physiology ; Signal Transduction ; Transcriptome/genetics
Czasopismo naukowe
Tytuł :
The factors influencing sludge incineration residue (SIR)-based magnesium potassium phosphate cement and the solidification/stabilization characteristics and mechanisms of heavy metals.
Autorzy :
Cao X; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Ma R; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Zhang Q; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Wang W; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Liao Q; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Sun S; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China; Research Center for Water Science and Environmental Engineering, Shenzhen University, 518055, China. Electronic address: .
Zhang P; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Liu X; Shenzhen Engineering Laboratory of Aerospace Detection and Imaging, Department of Materials Science and Engineering, Harbin Institute of Technology (Shenzhen), Shenzhen, 518055, China.
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Źródło :
Chemosphere [Chemosphere] 2020 Dec; Vol. 261, pp. 127789. Date of Electronic Publication: 2020 Jul 26.
Typ publikacji :
Journal Article
MeSH Terms :
Construction Materials*
Incineration/*methods
Metals, Heavy/*chemistry
Phosphates/*chemistry
Potassium Compounds/*chemistry
Compressive Strength ; Magnesium ; Magnesium Compounds ; Minerals/chemistry ; Potassium ; Sewage/chemistry
Czasopismo naukowe

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