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Wyszukujesz frazę ""PRION diseases"" wg kryterium: Temat


Tytuł:
Detection limitations of prion seeding activities in blood samples from patients with sporadic prion disease.
Autorzy:
Nonaka T; Division of Cellular and Molecular Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki City, 852-8501, Japan.
Iwasaki Y; Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Nagakute City, 480-1195, Japan.
Horiuchi H; Laboratory of Immunobiology, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashihiroshima City, Japan.
Satoh K; Department of Health Sciences, Unit of Medical and Dental Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki City, Japan. satoh-prion@nagasaki-u.ac.jp.
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Źródło:
BMC neurology [BMC Neurol] 2024 Mar 11; Vol. 24 (1), pp. 92. Date of Electronic Publication: 2024 Mar 11.
Typ publikacji:
Journal Article
MeSH Terms:
Prions*/metabolism
Prion Diseases*/diagnosis
Prion Diseases*/metabolism
Creutzfeldt-Jakob Syndrome*/diagnosis
Humans ; Prion Proteins ; Brain/metabolism ; Plasma/metabolism
Czasopismo naukowe
Tytuł:
Single nucleotide polymorphisms (SNPs) in the open reading frame (ORF) of prion protein gene (PRNP) in Nigerian livestock species.
Autorzy:
Adeola AC; State Key Laboratory of Genetic Resources and Evolution & Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China. .; Sino-Africa Joint Research Center, Chinese Academy of Sciences, Kunming, China. .
Bello SF; Department of Animal Genetics, Breeding and Reproduction, College of Animal Science, South China Agricultural University, 510642, Guangzhou, China.
Abdussamad AM; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, Bayero University, Kano, Nigeria.
Adedokun RAM; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Olaogun SC; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Abdullahi N; Department of Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, Bayero University, Kano, Nigeria.
Mark AI; Ministry of Agriculture and Rural Development, Secretariat, Ibadan, Nigeria.
Onoja AB; Department of Virology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Sanke OJ; Taraba State Ministry of Agriculture and Natural Resources, Jalingo, Nigeria.
Mangbon GF; Division of Veterinary Office, Serti, Nigeria.
Ibrahim J; Department of Veterinary Surgery and Theriogenology, College of Veterinary Medicine, University of Agriculture Makurdi, Makurdi, Nigeria.
Dawuda PM; Department of Animal Science, Faculty of Agriculture, National University of Lesotho, Maseru, South Africa.
Salako AE; Department of Animal Science, Faculty of Agriculture, University of Ibadan, Ibadan, Nigeria.
Kdidi S; Livestock and Wildlife Laboratory, Institut des Régions Arides, Université de Gabes, Route El Djorf, Km 22.5, 4119, Medenine, Tunisia.
Yahyaoui MH; Livestock and Wildlife Laboratory, Institut des Régions Arides, Université de Gabes, Route El Djorf, Km 22.5, 4119, Medenine, Tunisia.
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Źródło:
BMC genomics [BMC Genomics] 2024 Feb 14; Vol. 25 (1), pp. 177. Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Prions*/genetics
Prions*/metabolism
Prion Diseases*/genetics
Prion Diseases*/veterinary
Scrapie*/genetics
Animals ; Horses/genetics ; Sheep/genetics ; Dogs ; Prion Proteins/genetics ; Polymorphism, Single Nucleotide ; Livestock/genetics ; Open Reading Frames ; Phylogeny ; Camelus/genetics ; Goats/genetics ; Goats/metabolism
Czasopismo naukowe
Tytuł:
Neural cell engraftment therapy for sporadic Creutzfeldt-Jakob disease restores neuroelectrophysiological parameters in a cerebral organoid model.
Autorzy:
Williams K; Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA.
Foliaki ST; Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA.
Race B; Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA.
Smith A; Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA.
Thomas T; Rocky Mountain Veterinary Branch, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA.
Groveman BR; Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA.
Haigh CL; Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA. .
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2023 Dec 05; Vol. 14 (1), pp. 348. Date of Electronic Publication: 2023 Dec 05.
Typ publikacji:
Journal Article
MeSH Terms:
Creutzfeldt-Jakob Syndrome*/therapy
Neurodegenerative Diseases*
Prions*
Prion Diseases*
Animals ; Humans ; Organoids
SCR Disease Name:
Creutzfeldt-Jakob Disease, Sporadic
Czasopismo naukowe
Tytuł:
Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease.
Autorzy:
Vicente-Rodríguez M; Department of Neuroimaging, BRAIN Centre (Biomarker Research and Imaging for Neuroscience), Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK. .; The Wellcome Trust Consortium for the Neuroimmunology of Mood Disorders and Alzheimer's Disease (NIMA), London, UK. .; Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain. .
Mancuso R; The Wellcome Trust Consortium for the Neuroimmunology of Mood Disorders and Alzheimer's Disease (NIMA), London, UK.; Microglia and Inflammation in Neurological Disorders (MIND) Lab, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Biological Sciences, Southampton General Hospital, University of Southampton, Southampton, UK.
Peris-Yague A; Department of Neuroimaging, BRAIN Centre (Biomarker Research and Imaging for Neuroscience), Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Simmons C; Department of Neuroimaging, BRAIN Centre (Biomarker Research and Imaging for Neuroscience), Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; The Wellcome Trust Consortium for the Neuroimmunology of Mood Disorders and Alzheimer's Disease (NIMA), London, UK.
Gómez-Nicola D; The Wellcome Trust Consortium for the Neuroimmunology of Mood Disorders and Alzheimer's Disease (NIMA), London, UK.; Biological Sciences, Southampton General Hospital, University of Southampton, Southampton, UK.
Perry VH; The Wellcome Trust Consortium for the Neuroimmunology of Mood Disorders and Alzheimer's Disease (NIMA), London, UK.; Biological Sciences, Southampton General Hospital, University of Southampton, Southampton, UK.
Turkheimer F; Department of Neuroimaging, BRAIN Centre (Biomarker Research and Imaging for Neuroscience), Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; The Wellcome Trust Consortium for the Neuroimmunology of Mood Disorders and Alzheimer's Disease (NIMA), London, UK.
Lovestone S; The Wellcome Trust Consortium for the Neuroimmunology of Mood Disorders and Alzheimer's Disease (NIMA), London, UK.; Janssen Medical Ltd, High Wycombe, UK.
Parker CA; Department of Neuroimaging, BRAIN Centre (Biomarker Research and Imaging for Neuroscience), Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; The Wellcome Trust Consortium for the Neuroimmunology of Mood Disorders and Alzheimer's Disease (NIMA), London, UK.; GlaxoSmithKline, Stevenage, London, UK.
Cash D; Department of Neuroimaging, BRAIN Centre (Biomarker Research and Imaging for Neuroscience), Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; The Wellcome Trust Consortium for the Neuroimmunology of Mood Disorders and Alzheimer's Disease (NIMA), London, UK.
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Corporate Authors:
NIMA Consortium
Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2023 Apr 09; Vol. 20 (1), pp. 92. Date of Electronic Publication: 2023 Apr 09.
Typ publikacji:
Journal Article
MeSH Terms:
Neurodegenerative Diseases*/metabolism
Prion Diseases*/metabolism
Mice ; Animals ; Microglia/metabolism ; Neuroinflammatory Diseases ; Endothelial Cells/metabolism ; Receptors, GABA/metabolism ; Positron-Emission Tomography/methods ; Macrophages/metabolism ; Brain/diagnostic imaging ; Brain/metabolism ; Neurons/metabolism ; Biomarkers/metabolism
Czasopismo naukowe
Tytuł:
Sporadic Creutzfeldt-Jakob disease infected human cerebral organoids retain the original human brain subtype features following transmission to humanized transgenic mice.
Autorzy:
Groveman BR; Laboratory of Persistent Viral Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT, 59840, USA.
Race B; Laboratory of Persistent Viral Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT, 59840, USA.
Foliaki ST; Laboratory of Persistent Viral Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT, 59840, USA.
Williams K; Laboratory of Persistent Viral Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT, 59840, USA.
Hughson AG; Laboratory of Persistent Viral Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT, 59840, USA.
Baune C; Laboratory of Persistent Viral Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT, 59840, USA.
Zanusso G; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Haigh CL; Laboratory of Persistent Viral Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT, 59840, USA. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Feb 14; Vol. 11 (1), pp. 28. Date of Electronic Publication: 2023 Feb 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Creutzfeldt-Jakob Syndrome*/metabolism
Neurodegenerative Diseases*/metabolism
Prions*/metabolism
Prion Diseases*/metabolism
Humans ; Mice ; Animals ; Mice, Transgenic ; Prion Proteins/genetics ; Prion Proteins/metabolism ; Brain/metabolism ; Organoids/metabolism
SCR Disease Name:
Creutzfeldt-Jakob Disease, Sporadic
Czasopismo naukowe
Tytuł:
Dysregulation of neuroprotective astrocytes, a spectrum of microglial activation states, and altered hippocampal neurogenesis are revealed by single-cell RNA sequencing in prion disease.
Autorzy:
Slota JA; One Health Division, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Sajesh BV; One Health Division, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
Frost KF; One Health Division, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
Medina SJ; One Health Division, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
Booth SA; One Health Division, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada. .; Department of Medical Microbiology and Infectious Diseases, Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2022 Nov 09; Vol. 10 (1), pp. 161. Date of Electronic Publication: 2022 Nov 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Astrocytes*/metabolism
Prion Diseases*/genetics
Prion Diseases*/metabolism
Animals ; Mice ; Microglia/metabolism ; Hippocampus/metabolism ; Neurogenesis ; Sequence Analysis, RNA
Czasopismo naukowe
Tytuł:
Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model.
Autorzy:
Vidal E; Unitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Catalonia, Spain.; IRTA Programa de Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Catalonia, Spain.
Sánchez-Martín MA; Transgenic Facility. Department of Medicine, University of Salamanca, 37007, Salamanca, Spain.
Eraña H; Centro de Investigación Cooperativa en Biociencias (CIC BioGUNE), Laboratorio de Investigación de Priones, Basque Research and Technology Alliance (BRTA), Derio, Bizkaia, Spain.; ATLAS Molecular Pharma S. L., Derio, Bizkaia, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain.
Lázaro SP; Centro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Universidad de Zaragoza-IA2, Zaragoza, Spain.
Pérez-Castro MA; Centro de Investigación Cooperativa en Biociencias (CIC BioGUNE), Laboratorio de Investigación de Priones, Basque Research and Technology Alliance (BRTA), Derio, Bizkaia, Spain.
Otero A; Centro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Universidad de Zaragoza-IA2, Zaragoza, Spain.
Charco JM; Centro de Investigación Cooperativa en Biociencias (CIC BioGUNE), Laboratorio de Investigación de Priones, Basque Research and Technology Alliance (BRTA), Derio, Bizkaia, Spain.; ATLAS Molecular Pharma S. L., Derio, Bizkaia, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain.
Marín B; Centro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Universidad de Zaragoza-IA2, Zaragoza, Spain.
López-Moreno R; Centro de Investigación Cooperativa en Biociencias (CIC BioGUNE), Laboratorio de Investigación de Priones, Basque Research and Technology Alliance (BRTA), Derio, Bizkaia, Spain.
Díaz-Domínguez CM; Centro de Investigación Cooperativa en Biociencias (CIC BioGUNE), Laboratorio de Investigación de Priones, Basque Research and Technology Alliance (BRTA), Derio, Bizkaia, Spain.
Geijo M; Animal Health Department, NEIKER-Basque Institute for Agricultural Research and Development, Basque Research and Technology Alliance (BRTA), Derio, Spain.
Ordóñez M; Unitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Catalonia, Spain.; IRTA Programa de Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Catalonia, Spain.
Cantero G; Unitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Catalonia, Spain.; IRTA Programa de Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Catalonia, Spain.
di Bari M; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore Di Sanità, 00161, Rome, Italy.
Lorenzo NL; CIMUS Biomedical Research Institute, University of Santiago de Compostela-IDIS, Santiago, Spain.
Pirisinu L; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore Di Sanità, 00161, Rome, Italy.
d'Agostino C; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore Di Sanità, 00161, Rome, Italy.
Torres JM; Centro de Investigación en Sanidad Animal (CISA), Centro Superior de Investigaciones Científicas (CSIC) Valdeolmos, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), 28130, Madrid, Spain.
Béringue V; Molecular Virology and Immunology, Institut National de La Recherche Agronomique (INRA), Université Paris-Saclay, Jouy-en-Josas, France.
Telling G; Prion Research Center (PRC) and the Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, USA.
Badiola JJ; Centro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Universidad de Zaragoza-IA2, Zaragoza, Spain.
Pumarola M; Departament de Medicina i Cirurgia Animals, Facultat de Veterinària, Campus de UAB, Bellaterra, 08193, Barcelona, Catalonia, Spain.
Bolea R; Centro de Encefalopatías y Enfermedades Transmisibles Emergentes, Facultad de Veterinaria, Universidad de Zaragoza-IA2, Zaragoza, Spain.
Nonno R; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore Di Sanità, 00161, Rome, Italy.
Requena JR; CIMUS Biomedical Research Institute, University of Santiago de Compostela-IDIS, Santiago, Spain.
Castilla J; Centro de Investigación Cooperativa en Biociencias (CIC BioGUNE), Laboratorio de Investigación de Priones, Basque Research and Technology Alliance (BRTA), Derio, Bizkaia, Spain. .; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain. .; IKERBASQUE, Basque Foundation for Science, Bilbao, Bizkaia, Spain. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2022 Dec 13; Vol. 10 (1), pp. 179. Date of Electronic Publication: 2022 Dec 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Scrapie*/metabolism
Prions*/metabolism
Prion Diseases*
Mice ; Animals ; Sheep ; Humans ; Rodentia/metabolism ; Mice, Transgenic ; Arvicolinae/metabolism
Czasopismo naukowe
Tytuł:
Sporadic Creutzfeldt-Jakob disease VM1: phenotypic and molecular characterization of a novel subtype of human prion disease.
Autorzy:
Gelpi E; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna and Austrian Reference Center for Human Prion Diseases (ÖRPE), AKH Leitstelle 4J, Waehringer Guertel 18-20, 1090, Vienna, Austria. .; Neurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Barcelona, Spain. .
Baiardi S; IRCCS Istituto delle Scienze Neurologiche di Bologna, Via Altura 1/8, 40139, Bologna, Italy.; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
Nos C; General Subdirectorate of Surveillance and Response to Emergencies in Public Health, Department of Public Health in Catalonia, Barcelona, Spain.
Dellavalle S; IRCCS Istituto delle Scienze Neurologiche di Bologna, Via Altura 1/8, 40139, Bologna, Italy.
Aldecoa I; Neurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Barcelona, Spain.; Department of Pathology, Center for Biomedical Diagnosis, Hospital Clinic de Barcelona, University of Barcelona, Barcelona, Spain.
Ruiz-Garcia R; Department of Immunology, Center for Biomedical Diagnosis, Hospital Clinic de Barcelona, Barcelona, Spain.
Ispierto L; Cognitive and Movement Disorders Unit, Hospital Germans Trias I Pujol de Badalona, Barcelona, Spain.
Escudero D; Cognitive and Movement Disorders Unit, Hospital Germans Trias I Pujol de Badalona, Barcelona, Spain.; Neurology Department, Alzheimer Disease and Other Cognitive Disorders Unit, Hospital Clinic de Barcelona, Barcelona, Spain.
Casado V; Neurology Department, Hospital de Mataró, Barcelona, Spain.
Barranco E; Department of Geriatrics, Hospital General de Granollers, Barcelona, Spain.
Boltes A; Department of Neurology, Hospital General de Granollers, Barcelona, Spain.
Molina-Porcel L; Neurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Barcelona, Spain.; Neurology Department, Alzheimer Disease and Other Cognitive Disorders Unit, Hospital Clinic de Barcelona, Barcelona, Spain.
Bargalló N; Radiology Department, Image Diagnosis Center, Hospital Clínic de Barcelona, Spain and Magnetic Resonance Image Core Facility of IDIBAPS, Barcelona, Spain.
Rossi M; IRCCS Istituto delle Scienze Neurologiche di Bologna, Via Altura 1/8, 40139, Bologna, Italy.
Mammana A; IRCCS Istituto delle Scienze Neurologiche di Bologna, Via Altura 1/8, 40139, Bologna, Italy.
Tiple D; Department of Neuroscience, Istituto Superiore di Sanità, 00161, Rome, Italy.
Vaianella L; Department of Neuroscience, Istituto Superiore di Sanità, 00161, Rome, Italy.
Stoegmann E; Department of Neurology, Medical University of Vienna, Vienna, Austria.
Simonitsch-Klupp I; Department of Pathology, Medical University of Vienna, Vienna, Austria.
Kasprian G; Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Klotz S; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna and Austrian Reference Center for Human Prion Diseases (ÖRPE), AKH Leitstelle 4J, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Höftberger R; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna and Austrian Reference Center for Human Prion Diseases (ÖRPE), AKH Leitstelle 4J, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Budka H; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna and Austrian Reference Center for Human Prion Diseases (ÖRPE), AKH Leitstelle 4J, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Kovacs GG; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology and Department of Medicine, University of Toronto, Toronto, ON, Canada.; Laboratory Medicine Program & Krembil Brain Institute, University Health Network, Toronto, ON, Canada.
Ferrer I; Department of Pathology and Experimental Therapeutics, University of BarcelonaBellvitge University Hospital-IDIBELLCIBERNED, Barcelona, Spain.
Capellari S; IRCCS Istituto delle Scienze Neurologiche di Bologna, Via Altura 1/8, 40139, Bologna, Italy.; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
Sanchez-Valle R; Neurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Barcelona, Spain.; Neurology Department, Alzheimer Disease and Other Cognitive Disorders Unit, Hospital Clinic de Barcelona, Barcelona, Spain.
Parchi P; IRCCS Istituto delle Scienze Neurologiche di Bologna, Via Altura 1/8, 40139, Bologna, Italy. .; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2022 Aug 17; Vol. 10 (1), pp. 114. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Creutzfeldt-Jakob Syndrome*/pathology
Prion Diseases*/pathology
Prions*/genetics
Prions*/metabolism
Animals ; Brain/pathology ; Codon/metabolism ; Humans ; Mice ; Prion Proteins/genetics ; Prion Proteins/metabolism
SCR Disease Name:
Creutzfeldt-Jakob Disease, Sporadic
Czasopismo naukowe
Tytuł:
RT-QuIC detection of pathological prion protein in subclinical goats following experimental oral transmission of L-type BSE.
Autorzy:
Favole A; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy. .
Mazza M; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy.
D'Angelo A; University of Turin, Grugliasco (Turin), Italy.
Lombardi G; Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia-Romagna, Brescia, Italy.
Palmitessa C; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy.
Dell'Atti L; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy.
Cagnotti G; University of Turin, Grugliasco (Turin), Italy.
Berrone E; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy.
Gallo M; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy.
Avanzato T; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy.
Messana E; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy.
Masoero L; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy.
Acutis PL; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy.
Meloni D; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy.
Cardone F; Istituto Superiore di Sanità, Rome, Italy.
Caramelli M; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy.
Casalone C; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy.
Corona C; S.C. Neuroscienze, Lab. di Neurobiologia Sperimentale, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Turin, Italy. .
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Źródło:
BMC research notes [BMC Res Notes] 2021 Dec 07; Vol. 14 (1), pp. 442. Date of Electronic Publication: 2021 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Encephalopathy, Bovine Spongiform*/diagnosis
Prion Diseases*/diagnosis
Prion Diseases*/veterinary
Prions*
Animals ; Brain/metabolism ; Cattle ; Goats ; Prion Proteins/metabolism ; Sheep
Czasopismo naukowe
Tytuł:
Prion type 2 selection in sporadic Creutzfeldt-Jakob disease affecting peripheral ganglia.
Autorzy:
Hofmann A; Prion and Dementia Research Unit, Institute of Neuropathology, University Medical Center, Göttingen, Germany.; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University Hospital Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Tübingen, Germany.
Wrede A; Institute of Neuropathology, Medical Faculty, Saarland University, Building 90.3, 66421, Homburg/Saar, Germany.
Jürgens-Wemheuer WM; Institute of Neuropathology, Medical Faculty, Saarland University, Building 90.3, 66421, Homburg/Saar, Germany.
Schulz-Schaeffer WJ; Institute of Neuropathology, Medical Faculty, Saarland University, Building 90.3, 66421, Homburg/Saar, Germany. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2021 Nov 24; Vol. 9 (1), pp. 187. Date of Electronic Publication: 2021 Nov 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Creutzfeldt-Jakob Syndrome/*metabolism
Prion Diseases/*metabolism
Prions/*metabolism
Trigeminal Ganglion/*metabolism
Creutzfeldt-Jakob Syndrome/pathology ; Ganglia, Spinal/metabolism ; Ganglia, Spinal/pathology ; Ganglia, Sympathetic/metabolism ; Ganglia, Sympathetic/pathology ; Humans ; Peripheral Nerves/metabolism ; Peripheral Nerves/pathology ; Prion Diseases/pathology ; Trigeminal Ganglion/pathology
SCR Disease Name:
Creutzfeldt-Jakob Disease, Sporadic
Czasopismo naukowe
Tytuł:
Absence of Apolipoprotein E is associated with exacerbation of prion pathology and promotes microglial neurodegenerative phenotype.
Autorzy:
Pankiewicz JE; Department of Neurology, New York University Grossman School of Medicine, 550 First Avenue, Science Building, Room 10-07, New York, NY, 10016, USA.; Department of Biochemistry and Molecular Pharmacology , New York University Grossman School of Medicine, New York, NY, 10016, USA.
Lizińczyk AM; Department of Neurology, New York University Grossman School of Medicine, 550 First Avenue, Science Building, Room 10-07, New York, NY, 10016, USA.
Franco LA; Department of Neurology, New York University Grossman School of Medicine, 550 First Avenue, Science Building, Room 10-07, New York, NY, 10016, USA.
Diaz JR; Department of Neurology, New York University Grossman School of Medicine, 550 First Avenue, Science Building, Room 10-07, New York, NY, 10016, USA.
Martá-Ariza M; Department of Neurology, New York University Grossman School of Medicine, 550 First Avenue, Science Building, Room 10-07, New York, NY, 10016, USA.
Sadowski MJ; Department of Neurology, New York University Grossman School of Medicine, 550 First Avenue, Science Building, Room 10-07, New York, NY, 10016, USA. .; Department of Psychiatry , New York University Grossman School of Medicine, New York, NY, 10016, USA. .; Department of Biochemistry and Molecular Pharmacology , New York University Grossman School of Medicine, New York, NY, 10016, USA. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2021 Sep 26; Vol. 9 (1), pp. 157. Date of Electronic Publication: 2021 Sep 26.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Apolipoproteins E/*metabolism
Microglia/*pathology
Nerve Degeneration/*pathology
Prion Diseases/*pathology
Animals ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Microglia/metabolism ; Nerve Degeneration/metabolism ; Phenotype ; Prion Diseases/metabolism
Czasopismo naukowe
Tytuł:
The degree of astrocyte activation is predictive of the incubation time to prion disease.
Autorzy:
Makarava N; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, 111 S. Penn St, Baltimore, MD, 21201, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Mychko O; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, 111 S. Penn St, Baltimore, MD, 21201, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Chang JC; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, 111 S. Penn St, Baltimore, MD, 21201, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Molesworth K; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, 111 S. Penn St, Baltimore, MD, 21201, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Baskakov IV; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, 111 S. Penn St, Baltimore, MD, 21201, USA. .; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2021 May 12; Vol. 9 (1), pp. 87. Date of Electronic Publication: 2021 May 12.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Astrocytes/*metabolism
Astrocytes/*pathology
Brain/*metabolism
Prion Diseases/*metabolism
Prion Diseases/*pathology
Transcriptome/*physiology
Animals ; Brain/pathology ; Female ; Forecasting ; Male ; Mice ; Mice, Inbred C57BL ; Prion Diseases/genetics ; Time Factors
Czasopismo naukowe
Tytuł:
Bovine adapted transmissible mink encephalopathy is similar to L-BSE after passage through sheep with the VRQ/VRQ genotype but not VRQ/ARQ.
Autorzy:
Cassmann E; Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, 1920 Dayton Avenue, P.O. Box 70, Ames, IA, 50010, USA.; Oak Ridge Institute for Science and Education (ORISE) through an interagency agreement between the U.S. Department of Energy (DOE) and the U.S. Department of Agriculture (USDA). ORISE is managed by ORAU under DOE contract number DE-SC0014664, Oak Ridge, USA.
Moore SJ; Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, 1920 Dayton Avenue, P.O. Box 70, Ames, IA, 50010, USA.; Oak Ridge Institute for Science and Education (ORISE) through an interagency agreement between the U.S. Department of Energy (DOE) and the U.S. Department of Agriculture (USDA). ORISE is managed by ORAU under DOE contract number DE-SC0014664, Oak Ridge, USA.
Kokemuller R; Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, 1920 Dayton Avenue, P.O. Box 70, Ames, IA, 50010, USA.
Balkema-Buschmann A; Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, -Isle of Riems, Greifswald, Germany.
Groschup M; Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, -Isle of Riems, Greifswald, Germany.
Nicholson E; Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, 1920 Dayton Avenue, P.O. Box 70, Ames, IA, 50010, USA.
Greenlee J; Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, 1920 Dayton Avenue, P.O. Box 70, Ames, IA, 50010, USA. .
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Źródło:
BMC veterinary research [BMC Vet Res] 2020 Oct 08; Vol. 16 (1), pp. 383. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji:
Journal Article
MeSH Terms:
Prion Diseases/*genetics
Prion Diseases/*transmission
Prion Proteins/*genetics
Prions/*genetics
Animals ; Brain/pathology ; Cattle ; Encephalopathy, Bovine Spongiform/genetics ; Encephalopathy, Bovine Spongiform/pathology ; Encephalopathy, Bovine Spongiform/transmission ; Mice, Transgenic ; PrPC Proteins/genetics ; Prion Diseases/pathology
Czasopismo naukowe
Tytuł:
Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease.
Autorzy:
Vallabh SM; Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, 02114, USA. .; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA. .; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 415 Main St., Cambridge, MA, 02142, USA. .; Prion Alliance, Cambridge, MA, 02139, USA. .
Minikel EV; Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, 02114, USA.; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 415 Main St., Cambridge, MA, 02142, USA.; Prion Alliance, Cambridge, MA, 02139, USA.
Williams VJ; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Carlyle BC; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.
McManus AJ; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Wennick CD; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Bolling A; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Trombetta BA; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Urick D; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Nobuhara CK; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Gerber J; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Duddy H; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Lachmann I; AJ Roboscreen GmbH, 04129, Leipzig, Germany.
Stehmann C; Australian National CJD Registry, University of Melbourne, Parkville, 3010, Australia.
Collins SJ; Australian National CJD Registry, University of Melbourne, Parkville, 3010, Australia.
Blennow K; Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, S-431 80, Mölndal, Sweden.
Zetterberg H; Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, S-431 80, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, S-431 80, Mölndal, Sweden.; UK Dementia Research Institute, University College London, London, WC1N 3BG, UK.; Department of Molecular Neuroscience, UCL Institute of Neurology, London, WC1N 3BG, UK.
Arnold SE; Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, 02114, USA. .; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA. .
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Źródło:
BMC medicine [BMC Med] 2020 Jun 18; Vol. 18 (1), pp. 140. Date of Electronic Publication: 2020 Jun 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers/*metabolism
Neurodegenerative Diseases/*diagnosis
Prion Diseases/*diagnosis
Adult ; Cohort Studies ; Female ; Humans ; Longitudinal Studies ; Male ; Neurodegenerative Diseases/blood ; Neurodegenerative Diseases/cerebrospinal fluid ; Prion Diseases/blood ; Prion Diseases/cerebrospinal fluid ; Reproducibility of Results ; Risk Factors
Czasopismo naukowe
Tytuł:
RNA-seq and network analysis reveal unique glial gene expression signatures during prion infection.
Autorzy:
Carroll JA; Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South Fourth Street, Hamilton, MT, 59840, USA. .
Race B; Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South Fourth Street, Hamilton, MT, 59840, USA.
Williams K; Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South Fourth Street, Hamilton, MT, 59840, USA.
Striebel J; Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South Fourth Street, Hamilton, MT, 59840, USA.
Chesebro B; Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South Fourth Street, Hamilton, MT, 59840, USA.
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Źródło:
Molecular brain [Mol Brain] 2020 May 07; Vol. 13 (1), pp. 71. Date of Electronic Publication: 2020 May 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Astrocytes/*metabolism
Brain/*metabolism
Microglia/*metabolism
Neurodegenerative Diseases/*metabolism
Organic Chemicals/*administration & dosage
Prion Diseases/*metabolism
Prions/*metabolism
Transcriptome/*genetics
Animals ; Apoptosis/genetics ; Brain/drug effects ; Brain/pathology ; CD11c Antigen/metabolism ; CD18 Antigens/metabolism ; Cluster Analysis ; Female ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/genetics ; Gene Ontology ; Gliosis ; Immunohistochemistry ; In Situ Hybridization ; Male ; Mice ; Mice, Inbred C57BL ; Neuroglia/metabolism ; Prion Diseases/drug therapy ; Prions/pathogenicity ; RNA-Seq ; Scrapie/metabolism ; Signal Transduction/drug effects ; Signal Transduction/genetics ; Transcriptome/drug effects
Czasopismo naukowe
Tytuł:
Core transcriptional regulatory circuits in prion diseases.
Autorzy:
Kim TK; Institute for Systems Biology, Seattle, WA, 98109, USA.
Lee I; Institute for Systems Biology, Seattle, WA, 98109, USA.
Cho JH; Institute for Systems Biology, Seattle, WA, 98109, USA.; Department of Structural Biology and Developmental Neurobiology, Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Canine B; McLaughlin Research Institute, Great Falls, MT, 59405, USA.
Keller A; Institute for Systems Biology, Seattle, WA, 98109, USA.
Price ND; Institute for Systems Biology, Seattle, WA, 98109, USA.
Hwang D; Center for Plant Aging Research, Institute for Basic Science, Daegu Gyeongbuk Institute of Science and Technology, Daegu, 42988, Republic of Korea. .; Department of Biological Sciences, Seoul National University, Seoul, 08826, Republic of Korea. .
Carlson G; McLaughlin Research Institute, Great Falls, MT, 59405, USA. .; Institute for Neurodegenerative Diseases, Weill Institute for Neurosciences, University of California, San Francisco, CA, 94158, USA. .
Hood L; Institute for Systems Biology, Seattle, WA, 98109, USA. .
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Źródło:
Molecular brain [Mol Brain] 2020 Jan 20; Vol. 13 (1), pp. 10. Date of Electronic Publication: 2020 Jan 20.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Gene Regulatory Networks/*genetics
Prion Diseases/*genetics
Animals ; Brain/metabolism ; Brain/pathology ; Endothelial Cells/metabolism ; Gene Ontology ; Mice ; Mice, Inbred C57BL ; Mice, Inbred Strains ; Neuroglia/metabolism ; Neurons/metabolism ; PrPC Proteins/metabolism ; PrPSc Proteins/metabolism ; Prion Diseases/pathology ; Prion Proteins/metabolism
Czasopismo naukowe
Tytuł:
Genetic prion diseases presenting as frontotemporal dementia: clinical features and diagnostic challenge.
Autorzy:
Chen, Zhongyun (AUTHOR)
Chu, Min (AUTHOR)
Liu, Li (AUTHOR)
Zhang, Jing (AUTHOR)
Kong, Yu (AUTHOR)
Xie, Kexin (AUTHOR)
Cui, Yue (AUTHOR)
Ye, Hong (AUTHOR)
Li, Junjie (AUTHOR)
Wang, Lin (AUTHOR)
Wu, Liyong (AUTHOR)
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Źródło:
Alzheimer's Research & Therapy. 6/29/2022, Vol. 14 Issue 1, p1-11. 11p.
Czasopismo naukowe
Tytuł:
Co-occurrence of chronic traumatic encephalopathy and prion disease.
Autorzy:
Nemani SK; Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA.
Notari S; Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA. .
Cali I; Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA.
Alvarez VE; VA Boston Healthcare System, Boston, MA, 02130, USA.; Department of Neurology and Pathology, Boston University School of Medicine, Boston, MA, 02118, USA.; Alzheimer's Disease Center and CTE Program, Boston University School of Medicine, Boston, MA, 02118, USA.
Kofskey D; National Prion Disease Pathology Surveillance Center, Case Western Reserve University, Cleveland, OH, 44106, USA.
Cohen M; Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA.; National Prion Disease Pathology Surveillance Center, Case Western Reserve University, Cleveland, OH, 44106, USA.
Stern RA; Alzheimer's Disease Center and CTE Program, Boston University School of Medicine, Boston, MA, 02118, USA.; Departments of Neurology, Neurosurgery, and Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, 02118, USA.
Appleby B; National Prion Disease Pathology Surveillance Center, Case Western Reserve University, Cleveland, OH, 44106, USA.; Departments of Neurology and Psychiatry, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA.
Abrams J; Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Center for Disease Control and Prevention, Atlanta, GA, 30333, USA.
Schonberger L; Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Center for Disease Control and Prevention, Atlanta, GA, 30333, USA.
McKee A; VA Boston Healthcare System, Boston, MA, 02130, USA.; Department of Neurology and Pathology, Boston University School of Medicine, Boston, MA, 02118, USA.; Alzheimer's Disease Center and CTE Program, Boston University School of Medicine, Boston, MA, 02118, USA.
Gambetti P; Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2018 Dec 18; Vol. 6 (1), pp. 140. Date of Electronic Publication: 2018 Dec 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Brain/*pathology
Chronic Traumatic Encephalopathy/*complications
Prion Diseases/*complications
Aged ; Aged, 80 and over ; Brain/metabolism ; Chronic Traumatic Encephalopathy/diagnostic imaging ; Humans ; Male ; Neurofibrillary Tangles/metabolism ; Neurofibrillary Tangles/pathology ; Prion Diseases/diagnostic imaging ; Prion Proteins/metabolism ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł:
Chronic wasting disease in Europe: new strains on the horizon.
Autorzy:
Tranulis, Michael Andreas (AUTHOR)
Gavier-Widén, Dolores (AUTHOR)
Våge, Jørn (AUTHOR)
Nöremark, Maria (AUTHOR)
Korpenfelt, Sirkka-Liisa (AUTHOR)
Hautaniemi, Maria (AUTHOR)
Pirisinu, Laura (AUTHOR)
Nonno, Romolo (AUTHOR)
Benestad, Sylvie Lafond (AUTHOR)
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Źródło:
Acta Veterinaria Scandinavica. 11/25/2021, Vol. 63 Issue 1, p1-15. 15p.
Czasopismo naukowe
Tytuł:
Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods.
Autorzy:
Tarutani A; Department of Dementia and Higher Brain Function, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan.; Department of Biological Science, Tokyo Metropolitan University, Minami-osawa, Hachioji, Tokyo, 192-0397, Japan.
Arai T; Department of Neuropsychiatry, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-8576, Japan.
Murayama S; Department of Neuropathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, 35-2 Sakaecho, Itabashi-ku, Tokyo, 173-0015, Japan.
Hisanaga SI; Department of Biological Science, Tokyo Metropolitan University, Minami-osawa, Hachioji, Tokyo, 192-0397, Japan.
Hasegawa M; Department of Dementia and Higher Brain Function, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2018 Apr 18; Vol. 6 (1), pp. 29. Date of Electronic Publication: 2018 Apr 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain/*metabolism
Prion Diseases/*pathology
Prion Diseases/*physiopathology
alpha-Synuclein/*metabolism
alpha-Synuclein/*toxicity
Amyloid ; Animals ; Brain/drug effects ; Brain/ultrastructure ; Cell Line, Tumor ; Dose-Response Relationship, Drug ; Gene Expression Regulation/drug effects ; Humans ; Lewy Body Disease/pathology ; Mice ; Mice, Inbred C57BL ; Microscopy, Immunoelectron ; Multiple System Atrophy/pathology ; Neuroblastoma/pathology ; Peptide Fragments/pharmacology ; Prion Diseases/metabolism ; Transfection ; alpha-Synuclein/genetics ; alpha-Synuclein/ultrastructure
Czasopismo naukowe

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