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Tytuł :
Generation of Pulmonary Endothelial Progenitor Cells for Cell-based Therapy Using Interspecies Mouse-Rat Chimeras.
Autorzy :
Wang G; Center for Lung Regenerative Medicine.
Wen B; Center for Lung Regenerative Medicine.
Ren X; Center for Lung Regenerative Medicine.
Li E; Center for Lung Regenerative Medicine.
Zhang Y; Center for Lung Regenerative Medicine.
Guo M; Division of Pulmonary Biology, and.
Xu Y; Division of Pulmonary Biology, and.
Whitsett JA; Division of Pulmonary Biology, and.
Kalin TV; Division of Pulmonary Biology, and.
Kalinichenko VV; Center for Lung Regenerative Medicine.; Division of Pulmonary Biology, and.; Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Research Foundation, Cincinnati, Ohio.
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Źródło :
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2021 Aug 01; Vol. 204 (3), pp. 326-338.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Stem Cell Transplantation*
Embryonic Stem Cells/*cytology
Endothelial Progenitor Cells/*cytology
Induced Pluripotent Stem Cells/*cytology
Persistent Fetal Circulation Syndrome/*therapy
Animals ; Animals, Newborn ; CRISPR-Cas Systems ; Chimera ; Disease Models, Animal ; Embryonic Stem Cells/metabolism ; Endothelial Progenitor Cells/metabolism ; Endothelial Progenitor Cells/transplantation ; Forkhead Transcription Factors/genetics ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Infant, Newborn ; Mice ; Persistent Fetal Circulation Syndrome/metabolism ; Persistent Fetal Circulation Syndrome/pathology ; Pluripotent Stem Cells ; RNA-Seq ; Rats ; Single-Cell Analysis
Czasopismo naukowe
Tytuł :
Role of Stromal Cell-Derived Factor-1 in Endothelial Progenitor Cell-Mediated Vascular Repair and Regeneration.
Autorzy :
Li JH; Department of Ultrasonography, China-Japan Union Hospital of Jilin University, Changchun, 130003, People's Republic of China.
Li Y; Department of Ambulatory Ward, China-Japan Union Hospital of Jilin University, Changchun, 130003, People's Republic of China.
Huang D; Department of Neurology, China-Japan Union Hospital of Jilin University, 126 XianTai Street, Changchun, 130003, People's Republic of China.
Yao M; Department of Neurology, China-Japan Union Hospital of Jilin University, 126 XianTai Street, Changchun, 130003, People's Republic of China. .
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Źródło :
Tissue engineering and regenerative medicine [Tissue Eng Regen Med] 2021 Oct; Vol. 18 (5), pp. 747-758. Date of Electronic Publication: 2021 Aug 27.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Endothelial Progenitor Cells*
Animals ; Ischemia ; Neovascularization, Physiologic ; Stem Cells ; Stromal Cells
Czasopismo naukowe
Tytuł :
An evidence that SARS-Cov-2/COVID-19 spike protein (SP) damages hematopoietic stem/progenitor cells in the mechanism of pyroptosis in Nlrp3 inflammasome-dependent manner.
Autorzy :
Kucia M; Stem Cell Institute at James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA. .; Department of Regenerative Medicine, Warsaw Medical University, Warsaw, Poland. .
Ratajczak J; Stem Cell Institute at James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.
Bujko K; Department of Regenerative Medicine, Warsaw Medical University, Warsaw, Poland.
Adamiak M; Department of Regenerative Medicine, Warsaw Medical University, Warsaw, Poland.
Ciechanowicz A; Department of Regenerative Medicine, Warsaw Medical University, Warsaw, Poland.
Chumak V; Department of Regenerative Medicine, Warsaw Medical University, Warsaw, Poland.
Brzezniakiewicz-Janus K; Department of Hematology, University of Zielona Gora, Hospital Gorzow Wlkp., Gorzów Wielkopolski, Poland.
Ratajczak MZ; Stem Cell Institute at James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA. .; Department of Regenerative Medicine, Warsaw Medical University, Warsaw, Poland. .; Department of Hematology, University of Zielona Gora, Hospital Gorzow Wlkp., Gorzów Wielkopolski, Poland. .
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Źródło :
Leukemia [Leukemia] 2021 Oct; Vol. 35 (10), pp. 3026-3029. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Pyroptosis*
Angiotensin-Converting Enzyme 2/*metabolism
Endothelial Progenitor Cells/*pathology
Hematopoietic Stem Cells/*pathology
Inflammasomes/*immunology
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Spike Glycoprotein, Coronavirus/*metabolism
Angiotensin-Converting Enzyme 2/genetics ; Endothelial Progenitor Cells/immunology ; Endothelial Progenitor Cells/metabolism ; Hematopoietic Stem Cells/immunology ; Hematopoietic Stem Cells/metabolism ; Humans ; Spike Glycoprotein, Coronavirus/genetics
Czasopismo naukowe
Tytuł :
Diverse cellular origins of adult blood vascular endothelial cells.
Autorzy :
Aquino JB; CONICET-Universidad Austral, Instituto de Investigaciones en Medicina Traslacional (IIMT), Developmental Biology & Regenerative Medicine Laboratory, Argentina. Electronic address: .
Sierra R; CONICET-Universidad Austral, Instituto de Investigaciones en Medicina Traslacional (IIMT), Developmental Biology & Regenerative Medicine Laboratory, Argentina.
Montaldo LA; CONICET-Universidad Austral, Instituto de Investigaciones en Medicina Traslacional (IIMT), Developmental Biology & Regenerative Medicine Laboratory, Argentina.
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Źródło :
Developmental biology [Dev Biol] 2021 Sep; Vol. 477, pp. 117-132. Date of Electronic Publication: 2021 May 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cell Lineage*
Endothelial Progenitor Cells*
Endothelium, Vascular/*cytology
Mesenchymal Stem Cells/*cytology
Adult ; Adult Stem Cells ; Animals ; Cell Plasticity ; Endothelium, Vascular/embryology ; Humans
Czasopismo naukowe
Tytuł :
Neovascularization and tissue regeneration by endothelial progenitor cells in ischemic stroke.
Autorzy :
Li J; Department of Neurology, Affiliated Hospital of Beihua University, 12 JieFang street, Jilin, 132011, People's Republic of China.
Ma Y; Department of Neurology, Affiliated Hospital of Beihua University, 12 JieFang street, Jilin, 132011, People's Republic of China.
Miao XH; Affiliated Hospital of ChangChun University of Traditional Chinese Medicine, Changchun, 130021, People's Republic of China.
Guo JD; Department of Neurology, Affiliated Hospital of Beihua University, 12 JieFang street, Jilin, 132011, People's Republic of China.
Li DW; Department of Neurology, Affiliated Hospital of Beihua University, 12 JieFang street, Jilin, 132011, People's Republic of China. .
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Źródło :
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2021 Sep; Vol. 42 (9), pp. 3585-3593. Date of Electronic Publication: 2021 Jul 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Brain Ischemia*/therapy
Endothelial Progenitor Cells*
Ischemic Stroke*
Stroke*/therapy
Humans ; Neovascularization, Pathologic ; Neovascularization, Physiologic
Czasopismo naukowe
Tytuł :
The Effect of Platelet-Rich Plasma on Endothelial Progenitor Cell Functionality.
Autorzy :
Sidiropoulou S; Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, School of Sciences, University of Ioannina, Ioannina, Greece.
Papadaki S; Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, School of Sciences, University of Ioannina, Ioannina, Greece.
Tsouka AN; Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, School of Sciences, University of Ioannina, Ioannina, Greece.
Koutsaliaris IK; Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, School of Sciences, University of Ioannina, Ioannina, Greece.
Chantzichristos VG; Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, School of Sciences, University of Ioannina, Ioannina, Greece.
Pantazi D; Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, School of Sciences, University of Ioannina, Ioannina, Greece.
Paschopoulos ME; Department of Obstetrics and Gynecology, School of Medicine, University of Ioannina, Ioannina, Greece.
Hansson KM; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Tselepis AD; Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, School of Sciences, University of Ioannina, Ioannina, Greece.
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Źródło :
Angiology [Angiology] 2021 Sep; Vol. 72 (8), pp. 776-786. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Communication*/drug effects
Blood Platelets/*metabolism
Endothelial Progenitor Cells/*metabolism
Platelet-Rich Plasma/*metabolism
Antigens, CD34/metabolism ; Biomarkers/metabolism ; Blood Platelets/drug effects ; Cells, Cultured ; Chemokine CCL2/metabolism ; Endothelial Progenitor Cells/drug effects ; Epoprostenol/metabolism ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Intercellular Adhesion Molecule-1/metabolism ; Platelet Aggregation/drug effects ; Platelet Aggregation Inhibitors/pharmacology ; Platelet-Rich Plasma/drug effects ; Ticagrelor/pharmacology
Czasopismo naukowe
Tytuł :
CD34+CD133+CD309+ circulating angiogenic cell level is reduced but positively related to hydroxychloroquine use in SLE patients-a case-control study and meta-regression analysis.
Autorzy :
Huang J; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Kow NY; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Division of Rheumatology, University Medicine Cluster, National University Health System, Singapore.
Lee HY; Institute of Molecular and Cell Biology (ICMB), Singapore.
Fairhurst AM; Institute of Molecular and Cell Biology (ICMB), Singapore.
Mak A; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Division of Rheumatology, University Medicine Cluster, National University Health System, Singapore.
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Źródło :
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2021 Aug 02; Vol. 60 (8), pp. 3936-3944.
Typ publikacji :
Journal Article; Meta-Analysis
MeSH Terms :
Endothelial Progenitor Cells/*cytology
Lupus Erythematosus, Systemic/*blood
AC133 Antigen/metabolism ; Adult ; Antigens, CD34/metabolism ; Antirheumatic Agents/therapeutic use ; Case-Control Studies ; Endothelial Progenitor Cells/metabolism ; Female ; Flow Cytometry ; Humans ; Hydroxychloroquine/therapeutic use ; Lupus Erythematosus, Systemic/drug therapy ; Male ; Middle Aged ; Regression Analysis ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Young Adult
Czasopismo naukowe
Tytuł :
Impact of REDV peptide density and its linker structure on the capture, movement, and adhesion of flowing endothelial progenitor cells in microfluidic devices.
Autorzy :
Mahara A; Department of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Kishibe Shim-machi, Suita, Osaka 564-8565, Japan.
Kitagawa K; Department of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Kishibe Shim-machi, Suita, Osaka 564-8565, Japan; Department of Materials Chemistry, Ryukoku University, Seta, Otsu 520-2194, Japan.
Otaka A; Department of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Kishibe Shim-machi, Suita, Osaka 564-8565, Japan.
Nakaoki T; Department of Materials Chemistry, Ryukoku University, Seta, Otsu 520-2194, Japan.
Ishihara K; Department of Materials Engineering, School of Engineering, The University of Tokyo, Tokyo, Japan.
Yamaoka T; Department of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Kishibe Shim-machi, Suita, Osaka 564-8565, Japan. Electronic address: .
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Źródło :
Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2021 Oct; Vol. 129, pp. 112381. Date of Electronic Publication: 2021 Aug 25.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelial Progenitor Cells*
Blood Vessel Prosthesis ; Cell Adhesion ; Lab-On-A-Chip Devices ; Peptides
Czasopismo naukowe
Tytuł :
Circulating Endothelial Progenitor Cells Are Preserved in Female Mice Exposed to Ambient Fine Particulate Matter Independent of Estrogen.
Autorzy :
Liu X; Center for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, School of Medicine, University of Missouri, Columbia, MO 65212, USA.; Department of Medical Pharmacology and Physiology, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Xiao Y; Center for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Zhu Q; Center for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Cui Y; Center for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Hao H; Center for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Wang M; Center for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, School of Medicine, University of Missouri, Columbia, MO 65212, USA.; Department of Medical Pharmacology and Physiology, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Cowan PJ; Immunology Research Centre, Department of Medicine, St. Vincent's Hospital, University of Melbourne, Melbourne 3065, Australia.
Korthuis RJ; Department of Medical Pharmacology and Physiology, School of Medicine, University of Missouri, Columbia, MO 65212, USA.; Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO 65211, USA.
Li G; Department of Surgery and Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Sun Q; College of Public Health, Ohio State University, Columbus, OH 43210, USA.
Liu Z; Center for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 04; Vol. 22 (13). Date of Electronic Publication: 2021 Jul 04.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelial Progenitor Cells/*drug effects
Endothelial Progenitor Cells/*metabolism
Particulate Matter/*toxicity
Acetylcysteine/pharmacology ; Animals ; Antioxidants/pharmacology ; Apoptosis/drug effects ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/metabolism ; Cytokines/blood ; Endothelial Progenitor Cells/pathology ; Estrogens/metabolism ; Female ; Inflammation Mediators/blood ; Male ; Mice ; Mice, Inbred C57BL ; Ovariectomy ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism ; Sex Factors
Czasopismo naukowe
Tytuł :
The in vitro effects of hepatoblastoma cells on the growth and differentiation of blasts in transient abnormal myelopoiesis associated with Down syndrome.
Autorzy :
Miyauchi J; Department of Pathology and Laboratory Medicine, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Chiba-ken, Japan. Electronic address: .
Kawaguchi H; Department of Pediatrics, National Defense Medical College, Tokorozawa, Saitama-ken, Japan.
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Źródło :
Leukemia research [Leuk Res] 2021 Jun; Vol. 105, pp. 106570. Date of Electronic Publication: 2021 Mar 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hepatoblastoma*/metabolism
Hepatoblastoma*/pathology
Hepatocytes*/metabolism
Hepatocytes*/pathology
Megakaryocyte Progenitor Cells*/metabolism
Megakaryocyte Progenitor Cells*/pathology
Down Syndrome/*pathology
Leukemoid Reaction/*pathology
Cell Differentiation/physiology ; Cell Line, Tumor ; Cell Proliferation/physiology ; Coculture Techniques ; Humans ; Intercellular Signaling Peptides and Proteins/metabolism ; Leukemia, Megakaryoblastic, Acute/pathology ; Myelopoiesis/physiology ; Stem Cells/metabolism ; Stem Cells/pathology
SCR Disease Name :
Myeloproliferative Syndrome, Transient
Czasopismo naukowe
Tytuł :
A Novel Relative High-Density Lipoprotein Index to Predict the Structural Changes in High-Density Lipoprotein and Its Ability to Inhibit Endothelial-Mesenchymal Transition.
Autorzy :
Lin FY; Taipei Heart Institute, Taipei Medical University, Taipei 110, Taiwan.; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; Division of Cardiology, Department of Internal Medicine and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan.
Lin YW; Institute of Oral Biology, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.
Shih CM; Taipei Heart Institute, Taipei Medical University, Taipei 110, Taiwan.; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; Division of Cardiology, Department of Internal Medicine and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan.
Lin SJ; Taipei Heart Institute, Taipei Medical University, Taipei 110, Taiwan.; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; Division of Cardiology, Department of Internal Medicine and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan.
Tung YT; Graduate Institute of Biotechnology, National Chung Hsing University, Taichung 238, Taiwan.
Li CY; Department of Anesthesiology and Graduate Institute of Clinical Medical Science, China Medical University and Hospital, Taichung 406, Taiwan.
Chen YH; Graduate Institute of Integrated Medicine, China Medical University, Taichung 406, Taiwan.; Department of Psychology, College of Medical and Health Science, Asia University, Taichung 413, Taiwan.
Lin CY; Healthcare Information and Management Department, Ming Chuan University, Taoyuan 333, Taiwan.
Tsai YT; Taipei Heart Institute, Taipei Medical University, Taipei 110, Taiwan.; Division of Cardiovascular Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 115, Taiwan.
Huang CY; Taipei Heart Institute, Taipei Medical University, Taipei 110, Taiwan.; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; Division of Cardiology, Department of Internal Medicine and Cardiovascular Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 14; Vol. 22 (10). Date of Electronic Publication: 2021 May 14.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelial Progenitor Cells/*metabolism
Lipoproteins, HDL/*chemistry
Lipoproteins, HDL/*metabolism
Aged ; Dyslipidemias/blood ; Endothelial Progenitor Cells/drug effects ; Female ; Gene Expression Regulation/drug effects ; Humans ; Lipoproteins, HDL/pharmacology ; Male ; Middle Aged ; Phosphatidylcholines/blood ; Phosphatidylcholines/chemistry ; Phosphatidylinositols/blood ; Phosphatidylinositols/chemistry ; Smad Proteins/metabolism ; Snail Family Transcription Factors/metabolism ; Transforming Growth Factor beta1/pharmacology ; Triglycerides/blood ; Triglycerides/chemistry ; Young Adult
Czasopismo naukowe
Tytuł :
Upregulating CXCR7 accelerates endothelial progenitor cell-mediated endothelial repair by activating Akt/Keap-1/Nrf2 signaling in diabetes mellitus.
Autorzy :
Jiang C; Department of Interventional Therapy, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University of Medicine, No. 639 Zhi Zao Ju Road, Shanghai, 200233, People's Republic of China.
Li R; Department of Radiology, The Sixth People's Hospital, Affiliated to Shanghai Jiao Tong University, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Xiu C; Department of Radiology, The Sixth People's Hospital, Affiliated to Shanghai Jiao Tong University, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Ma X; Department of Radiology, The Sixth People's Hospital, Affiliated to Shanghai Jiao Tong University, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Hu H; Department of Radiology, The Sixth People's Hospital, Affiliated to Shanghai Jiao Tong University, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Wei L; Department of Radiology, The Sixth People's Hospital, Affiliated to Shanghai Jiao Tong University, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China.
Tang Y; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, 225001, People's Republic of China.
Tao M; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, 225001, People's Republic of China.
Zhao J; Department of Radiology, The Sixth People's Hospital, Affiliated to Shanghai Jiao Tong University, 600 Yi-Shan Road, Shanghai, 200233, People's Republic of China. .
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Źródło :
Stem cell research & therapy [Stem Cell Res Ther] 2021 May 03; Vol. 12 (1), pp. 264. Date of Electronic Publication: 2021 May 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Experimental*
Endothelial Progenitor Cells*/metabolism
Animals ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Receptors, CXCR ; Signal Transduction
Czasopismo naukowe
Tytuł :
MiR-222-3p downregulation prompted the migration, invasion and recruitment of endothelial progenitor cells via ADIPOR1 expression increase-induced AMKP activation.
Autorzy :
Gao L; Department of Cardiovascular Medicine, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuanjiagang, Yuzhong District, Chongqing 400016, China.
Chen M; Department of Heart and Vascular Surgery, Cardiovascular Disease Center, The Third Affiliated Hospital of Chongqing Medical University, No. 1 Shuanghu Branch Road, Huixing Street, Yubei District, Chongqing 401120, China.
Li F; Department of Heart and Vascular Surgery, Cardiovascular Disease Center, The Third Affiliated Hospital of Chongqing Medical University, No. 1 Shuanghu Branch Road, Huixing Street, Yubei District, Chongqing 401120, China. Electronic address: .
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Źródło :
Microvascular research [Microvasc Res] 2021 May; Vol. 135, pp. 104134. Date of Electronic Publication: 2021 Jan 09.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Movement*
Neovascularization, Physiologic*
AMP-Activated Protein Kinases/*metabolism
Aorta, Abdominal/*enzymology
Aortic Aneurysm, Abdominal/*enzymology
Endothelial Progenitor Cells/*enzymology
MicroRNAs/*metabolism
Receptors, Adiponectin/*metabolism
Animals ; Antagomirs/genetics ; Antagomirs/metabolism ; Aorta, Abdominal/pathology ; Aortic Aneurysm, Abdominal/genetics ; Aortic Aneurysm, Abdominal/pathology ; Cells, Cultured ; Disease Models, Animal ; Down-Regulation ; Endothelial Progenitor Cells/pathology ; Enzyme Activation ; Humans ; Male ; MicroRNAs/genetics ; Phosphorylation ; Rats, Sprague-Dawley ; Receptors, Adiponectin/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy.
Autorzy :
Wang L; MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, China.
Shao X; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Zhong T; Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Wu Y; MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, China.
Xu A; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Sun X; MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, China.
Gao H; MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, China.
Liu Y; MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, China.
Lan T; MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, China.
Tong Y; MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, China.
Tao X; Department of Research, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Du W; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Wang W; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Chen Y; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Li T; MOE Key Laboratory of Bioinformatics, Centre for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing, China.; National Center for Protein Science, Tsinghua University, Beijing, China.
Meng X; National Center for Protein Science, Tsinghua University, Beijing, China.
Deng H; MOE Key Laboratory of Bioinformatics, Centre for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing, China.; National Center for Protein Science, Tsinghua University, Beijing, China.
Yang B; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
He Q; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Ying M; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China. .
Rao Y; MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, China. .; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, China. .
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Źródło :
Nature chemical biology [Nat Chem Biol] 2021 May; Vol. 17 (5), pp. 567-575. Date of Electronic Publication: 2021 Mar 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Cell Differentiation/*drug effects
Gene Expression Regulation, Leukemic/*drug effects
Myeloid Progenitor Cells/*drug effects
Proteolysis/*drug effects
Triazoles/*pharmacology
Antineoplastic Agents/chemical synthesis ; Aurora Kinase A/genetics ; Aurora Kinase A/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Cyclin-Dependent Kinase 2/antagonists & inhibitors ; Cyclin-Dependent Kinase 2/genetics ; Cyclin-Dependent Kinase 2/metabolism ; Drug Design ; Drug Discovery ; Humans ; Ikaros Transcription Factor/genetics ; Ikaros Transcription Factor/metabolism ; Inhibitory Concentration 50 ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/enzymology ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/pathology ; Myeloid Progenitor Cells/enzymology ; Myeloid Progenitor Cells/pathology ; Piperazines/pharmacology ; Primary Cell Culture ; Pyridines/pharmacology ; Pyrimidines/pharmacology ; Quinazolines/pharmacology ; Signal Transduction ; Structure-Activity Relationship ; Transcriptome ; Triazoles/chemical synthesis
Czasopismo naukowe
Tytuł :
Quality and quantity culture effectively restores functional and proliferative capacities of endothelial progenitor cell in end-stage renal disease patients.
Autorzy :
Huang TH; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
Lee MS; Department of Orthopedics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
Sung PH; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
Chen YL; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
Chiang JY; Department of Computer Science and Engineering, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan; Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Yang CC; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
Sheu JJ; Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
Yip HK; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan; Department of Nursing, Asia University, Taichung 41354, Taiwan; Division of Cardiology, Department of Internal Medicine, Xiamen Chang Gung Hospital, Xiamen 361028, Fujian, China. Electronic address: .
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Źródło :
Stem cell research [Stem Cell Res] 2021 May; Vol. 53, pp. 102264. Date of Electronic Publication: 2021 Mar 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endothelial Progenitor Cells*
Kidney Failure, Chronic*
Cells, Cultured ; Humans ; Leukocytes, Mononuclear ; Macrophages
Czasopismo naukowe
Tytuł :
Factors Affecting the Re-Endothelialization of Endothelial Progenitor Cell.
Autorzy :
Xia LZ; Key Laboratory for Arteriosclerology of Hunan Province, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang Medical College, University of South China, Hengyang, China.
Tao J; Key Laboratory for Arteriosclerology of Hunan Province, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang Medical College, University of South China, Hengyang, China.
Chen YJ; Key Laboratory for Arteriosclerology of Hunan Province, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang Medical College, University of South China, Hengyang, China.
Liang LL; Key Laboratory for Arteriosclerology of Hunan Province, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang Medical College, University of South China, Hengyang, China.
Luo GF; Department of Gynaecology, The First Affiliated Hospital of University of South China, Hengyang, China.
Cai ZM; Pediatrics Department, The First Affiliated Hospital of University of South China, Hengyang, China.
Wang Z; Key Laboratory for Arteriosclerology of Hunan Province, Institute of Cardiovascular Disease, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang Medical College, University of South China, Hengyang, China.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2021 Jul; Vol. 40 (7), pp. 1009-1025. Date of Electronic Publication: 2021 May 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Endothelial Progenitor Cells/*metabolism
Endothelium, Vascular/*metabolism
Endothelium, Vascular/*physiology
Animals ; Arteries/injuries ; Cell Movement ; Endothelial Progenitor Cells/physiology ; Humans ; Signal Transduction/genetics ; Vascular System Injuries/physiopathology ; Veins/injuries
Czasopismo naukowe
Tytuł :
Exercise Training Improves Functions of Endothelial Progenitor Cells in Patients with Metabolic Syndrome.
Autorzy :
Tan Q; Qinhuangdao First Hospital,Qinhuangdao - China.
Li Y; Qinhuangdao First Hospital,Qinhuangdao - China.
Guo Y; Qinhuangdao First Hospital,Qinhuangdao - China.
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Transliterated Title :
Exercício Físico Melhora as Funções das Células Progenitoras Endoteliais em Pacientes com Síndrome Metabólica.
Źródło :
Arquivos brasileiros de cardiologia [Arq Bras Cardiol] 2021 Jul; Vol. 117 (1), pp. 108-117.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endothelial Progenitor Cells*
Metabolic Syndrome*/therapy
Cells, Cultured ; Exercise ; Humans ; Nitric Oxide ; Nitric Oxide Synthase Type III/metabolism ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł :
Endothelial Progenitor Cells and Exercise: Working Together to Target Endothelial Dysfunction in Metabolic Syndrome.
Autorzy :
Silva CGSE; Clínica de Medicina do Exercício - CLINIMEX,Rio de Janeiro, RJ - Brasil.
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Transliterated Title :
Células Progenitoras Endoteliais e Exercício: Trabalhando Juntos Contra a Disfunção Endotelial na Síndrome Metabólica.
Źródło :
Arquivos brasileiros de cardiologia [Arq Bras Cardiol] 2021 Jul; Vol. 117 (1), pp. 118-119.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Endothelial Progenitor Cells*
Metabolic Syndrome*
Vascular Diseases*
Exercise ; Humans
Opinia redakcyjna
Tytuł :
PGC-1α gene transfer restores adhesion and reendothelialization of endothelial progenitor cells from patients with hypertension.
Autorzy :
Xie W; Department of Hypertension and Vascular Disease, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Wu F; Department of Hypertension and Vascular Disease, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
He J; Department of Hypertension and Vascular Disease, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Su C
Chen L; Department of Hypertension and Vascular Disease, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Zhang X; Department of Hypertension and Vascular Disease, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Sun J; Department of Hypertension and Vascular Disease, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Liu X; Department of Hypertension and Vascular Disease, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China. .
Tao J; Department of Hypertension and Vascular Disease, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China. .
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Źródło :
Journal of human hypertension [J Hum Hypertens] 2021 Jun; Vol. 35 (6), pp. 510-516. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carotid Artery Injuries*
Endothelial Progenitor Cells*
Hypertension*/genetics
Animals ; Cells, Cultured ; Humans ; Mice ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
Isolation of Mouse Megakaryocyte Progenitors.
Autorzy :
Kimmerlin Q; Université de Strasbourg, INSERM UMR S1255, EFS Grand-EST.
Tavian M; UMR-S1113 -IRFAC, Université de Strasbourg.
Gachet C; Université de Strasbourg, INSERM UMR S1255, EFS Grand-EST.
Lanza F; Université de Strasbourg, INSERM UMR S1255, EFS Grand-EST.
Brouard N; Université de Strasbourg, INSERM UMR S1255, EFS Grand-EST; .
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2021 May 20 (171). Date of Electronic Publication: 2021 May 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Megakaryocyte Progenitor Cells*/cytology
Megakaryocytes*/cytology
Animals ; Bone Marrow Cells/cytology ; Cell Differentiation/physiology ; Cell Separation/methods ; Hematopoietic Stem Cells/cytology ; Mice
Czasopismo naukowe

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