Temat: "PURINES" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Analysis of post-market adverse events of istradefylline: a real-world study base on FAERS database.
Autorzy:: Jiang Y; Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, 214151, Jiangsu, China.
Lu R; Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, 214151, Jiangsu, China.
Zhou Q; Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, 214151, Jiangsu, China.
Shen Y; Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, 214151, Jiangsu, China. .
Zhu H; Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, 214151, Jiangsu, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Apr 01; Vol. 14 (1), pp. 7659. Date of Electronic Publication: 2024 Apr 01.
Typ publikacji:: Journal Article
MeSH Terms:: Compulsive Behavior*
Purines*/adverse effects
United States ; Databases, Factual ; Drug Evaluation, Preclinical ; United States Food and Drug Administration

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Skocz do pozycji: 2.

Tytuł:: Effectiveness and safety of baricitinib in patients with moderate-to-severe refractory alopecia areata in real world: An open-label, single-center study.
Autorzy:: Bi L; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Wang C; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Du Y; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Su T; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Department of Dermatology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Zhao M; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Lin X; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Fan W; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Sun W; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Pokaż więcej
Źródło:: Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Apr; Vol. 23 (4), pp. 1417-1421. Date of Electronic Publication: 2023 Dec 20.
Typ publikacji:: Journal Article
MeSH Terms:: Alopecia Areata*/drug therapy
Janus Kinase Inhibitors*/adverse effects
Azetidines*
Purines*
Pyrazoles*
Sulfonamides*
Male ; Female ; Humans ; Retrospective Studies ; Immunoglobulin A/therapeutic use
SCR Disease Name:: Diffuse alopecia

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Skocz do pozycji: 3.

Tytuł:: IRF1 Mediates Growth Arrest and the Induction of a Secretory Phenotype in Alveolar Epithelial Cells in Response to Inflammatory Cytokines IFNγ/TNFα.
Autorzy:: Recchia Luciani G; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Barilli A; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Visigalli R; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Sala R; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Dall'Asta V; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Rotoli BM; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 19; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:: Journal Article
MeSH Terms:: Azetidines*
Cytokines*/metabolism
Purines*
Pyrazoles*
Sulfonamides*
Tumor Necrosis Factor-alpha*/metabolism
Alveolar Epithelial Cells/metabolism ; Cellular Senescence ; Interleukin-6/metabolism ; Phenotype ; A549 Cells ; Humans

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Skocz do pozycji: 4.

Tytuł:: Comprehensive study on in vitro propagation of some imported peach rootstocks: in vitro explant surface sterilization and bud proliferation.
Autorzy:: Eliwa GI; Horticulture Department, Faculty of Agriculture, Damietta University, New Damietta, Egypt. .
El-Dengawy EF; Horticulture Department, Faculty of Agriculture, Damietta University, New Damietta, Egypt.
Gawish MS; Horticulture Department, Faculty of Agriculture, Damietta University, New Damietta, Egypt.
Yamany MM; Horticulture Department, Faculty of Agriculture, Damietta University, New Damietta, Egypt.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 07; Vol. 14 (1), pp. 5586. Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:: Journal Article
MeSH Terms:: Prunus persica*
Purines*
Humans ; Plant Shoots ; Benzyl Compounds ; Cell Proliferation

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Skocz do pozycji: 5.

Tytuł:: A systematic review of case series and clinical trials investigating systemic oral or injectable therapies for the treatment of vitiligo.
Autorzy:: Jafarzadeh A; Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Pour Mohammad A; Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Khosravi M; Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Amiri S; Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Rasouli A; School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Keramati H; Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Goodarzi A; Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.; Pokaż więcej
Źródło:: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) [Skin Res Technol] 2024 Mar; Vol. 30 (3), pp. e13642.
Typ publikacji:: Systematic Review; Journal Article; Review
MeSH Terms:: Vitiligo*/drug therapy
Vitiligo*/pathology
Hypopigmentation*
Purines*
Pyrazoles*
Sulfonamides*
Azetidines*
Thalidomide/*analogs & derivatives
Humans ; Methotrexate/therapeutic use ; Azathioprine/therapeutic use ; Mycophenolic Acid/therapeutic use ; Minocycline/therapeutic use ; Alefacept/therapeutic use ; Cyclosporine/therapeutic use ; Adrenal Cortex Hormones ; Simvastatin/therapeutic use ; Zinc/therapeutic use

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Skocz do pozycji: 6.

Tytuł:: Machine learning-mediated Passiflora caerulea callogenesis optimization.
Autorzy:: Jafari M; Department of Horticultural Science, College of Agriculture, Shiraz University, Shiraz, Iran.; Department of Horticultural Sciences, Agricultural Sciences and Natural Resources University of Khuzestan, Mollasani, Iran.
Daneshvar MH; Department of Horticultural Sciences, Agricultural Sciences and Natural Resources University of Khuzestan, Mollasani, Iran.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Jan 24; Vol. 19 (1), pp. e0292359. Date of Electronic Publication: 2024 Jan 24 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Passiflora*
Benzyl Compounds*
Purines*
Algorithms ; Machine Learning ; 2,4-Dichlorophenoxyacetic Acid/pharmacology

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Skocz do pozycji: 7.

Tytuł:: Methylglyoxal activates transient receptor potential A1/V1 via reactive oxygen species in the spinal dorsal horn.
Autorzy:: Ueno T; Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan.
Yamanaka M; Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan.
Taniguchi W; Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan.
Nishio N; Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan.
Matsuyama Y; Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan.
Miyake R; Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan.
Kaimochi Y; Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan.
Nakatsuka T; Pain Research Center, Kansai University of Health Sciences, Osaka, Japan.
Yamada H; Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan.; Pokaż więcej
Źródło:: Molecular pain [Mol Pain] 2024 Jan-Dec; Vol. 20, pp. 17448069241233744.
Typ publikacji:: Journal Article
MeSH Terms:: Pyruvaldehyde*/pharmacology
Pyruvaldehyde*/metabolism
Magnesium Oxide*/metabolism
Magnesium Oxide*/pharmacology
Acetanilides*
Purines*
Capsaicin/*analogs & derivatives
Rats ; Animals ; Reactive Oxygen Species/metabolism ; Rats, Sprague-Dawley ; Spinal Cord Dorsal Horn/metabolism ; Posterior Horn Cells/metabolism ; Pain/metabolism ; Synaptic Transmission/physiology

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Skocz do pozycji: 8.

Tytuł:: Glutathione-Mediated Neuroprotective Effect of Purine Derivatives.
Autorzy:: Matsumura N; Department of Pharmacology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi, Tokyo 173-8605, Japan.
Aoyama K; Department of Pharmacology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi, Tokyo 173-8605, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 22; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 22.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Alzheimer Disease*/drug therapy
Alzheimer Disease*/prevention & control
Glutathione*/metabolism
Neuroprotection*
Neuroprotective Agents*/chemistry
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Parkinson Disease*/drug therapy
Parkinson Disease*/prevention & control
Purines*/chemistry
Purines*/pharmacology
Purines*/therapeutic use
Humans ; Adenosine A2 Receptor Antagonists/chemistry ; Adenosine A2 Receptor Antagonists/pharmacology ; Adenosine A2 Receptor Antagonists/therapeutic use ; Brain/metabolism ; Cysteine/metabolism ; Excitatory Amino Acid Transporter 3/metabolism ; Receptor, Adenosine A2A ; Theophylline/chemistry ; Theophylline/pharmacology ; Theophylline/therapeutic use ; Uric Acid/blood ; Caffeine/chemistry ; Caffeine/pharmacology ; Caffeine/therapeutic use

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Skocz do pozycji: 9.

Tytuł:: Purine Biosynthesis Pathways Are Required for Myogenesis in Xenopus laevis .
Autorzy:: Duperray M; Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.
Hardet F; CNRS, IMN, UMR 5293, Université de Bordeaux, F-33000 Bordeaux, France.
Henriet E; CNRS, IMN, UMR 5293, Université de Bordeaux, F-33000 Bordeaux, France.
Saint-Marc C; Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.
Boué-Grabot E; CNRS, IMN, UMR 5293, Université de Bordeaux, F-33000 Bordeaux, France.
Daignan-Fornier B; Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.
Massé K; CNRS, IMN, UMR 5293, Université de Bordeaux, F-33000 Bordeaux, France.
Pinson B; Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Sep 28; Vol. 12 (19). Date of Electronic Publication: 2023 Sep 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Muscle, Skeletal*/metabolism
Purines*/metabolism
Animals ; Xenopus laevis/genetics ; Muscle Development/genetics

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Skocz do pozycji: 10.

Tytuł:: A2BAR Antagonism Decreases the Glomerular Expression and Secretion of Chemoattractants for Monocytes and the Pro-Fibrotic M2 Macrophages Polarization during Diabetic Nephropathy.
Autorzy:: Torres-Arévalo Á; Escuela de Medicina Veterinaria, Facultad de Medicina Veterinaria Y Recursos Naturales, Sede Talca, Universidad Santo Tomás, Talca 347-3620, Chile.
Nahuelpán Y; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Muñoz K; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Jara C; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Cappelli C; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Taracha-Wiśniewska A; Faculty of Biology, Institute of Genetics and Biotechnology, University of Warsaw, 02-106 Warsaw, Poland.
Quezada-Monrás C; Tumor Biology Laboratory, Institute of Biochemistry and Microbiology, Faculty of Sciences, Universidad Austral de Chile, Valdivia 511-0566, Chile.; Millennium Institute on Immunology and Immunotherapy, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Martín RS; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 29; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 29.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetic Nephropathies*/genetics
Diabetic Nephropathies*/immunology
Kidney Glomerulus*/drug effects
Kidney Glomerulus*/metabolism
Chemotactic Factors*/antagonists & inhibitors
Chemotactic Factors*/genetics
Chemotactic Factors*/metabolism
Cell Polarity*/drug effects
Cell Polarity*/immunology
Macrophages*/drug effects
Macrophages*/immunology
Adenosine A2 Receptor Antagonists*/pharmacology
Acetamides*/pharmacology
Purines*/pharmacology
Receptor, Adenosine A2B ; Animals ; Rats ; Cell Movement/drug effects ; Male ; Rats, Sprague-Dawley ; Transcription, Genetic/drug effects ; Protein Biosynthesis/drug effects ; Immunity/drug effects ; Immunity/genetics

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Skocz do pozycji: 11.

Tytuł:: Allopurinol Disrupts Purine Metabolism to Increase Damage in Experimental Colitis.
Autorzy:: Worledge CS; Mucosal Inflammation Program, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Kostelecky RE; Mucosal Inflammation Program, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Zhou L; Mucosal Inflammation Program, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Bhagavatula G; Mucosal Inflammation Program, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Colgan SP; Mucosal Inflammation Program, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.; Rocky Mountain Regional Veterans Affairs Medical Center, Aurora, CO 80045, USA.
Lee JS; Mucosal Inflammation Program, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Feb 21; Vol. 13 (5). Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:: Journal Article
MeSH Terms:: Colitis*/drug therapy
Inflammatory Bowel Diseases*/drug therapy
Humans ; Mice ; Animals ; Allopurinol ; Purines/metabolism ; Hypoxanthine/metabolism

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Skocz do pozycji: 12.

Tytuł:: Transposon sequencing reveals metabolic pathways essential for Mycobacterium tuberculosis infection.
Autorzy:: Block AM; Department of Microbiology and Immunology, University of Minnesota, Twin Cities Campus, Minneapolis, Minnesota, United States of America.
Wiegert PC; Department of Microbiology and Immunology, University of Minnesota, Twin Cities Campus, Minneapolis, Minnesota, United States of America.
Namugenyi SB; Department of Microbiology and Immunology, University of Minnesota, Twin Cities Campus, Minneapolis, Minnesota, United States of America.
Tischler AD; Department of Microbiology and Immunology, University of Minnesota, Twin Cities Campus, Minneapolis, Minnesota, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2024 Mar 18; Vol. 20 (3), pp. e1011663. Date of Electronic Publication: 2024 Mar 18 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Tuberculosis*/genetics
Mycobacterium tuberculosis*/genetics
Animals ; Mice ; Mutation ; Metabolic Networks and Pathways/genetics ; Thiamine ; Purines ; Mammals

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Skocz do pozycji: 13.

Tytuł:: Machine learning identifies fatigue as a key symptom of fibromyalgia reflected in tyrosine, purine, pyrimidine, and glutaminergic metabolism.
Autorzy:: Zetterman T; Department of Anaesthesiology, Intensive Care and Pain Medicine, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.; Wellbeing Services County of Vantaa and Kerava, Vantaa and Kerava, Finland.; Department of General Practice and Primary Health Care, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Nieminen AI; FIMM Metabolomics Unit, Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
Markkula R; Department of Anaesthesiology, Intensive Care and Pain Medicine, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Kalso E; Department of Anaesthesiology, Intensive Care and Pain Medicine, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.; SleepWell Research Programme, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Lötsch J; Institute of Clinical Pharmacology, Goethe-University, Frankfurt am Main, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Frankfurt am Main, Germany.; Pokaż więcej
Źródło:: Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13740.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Fibromyalgia*/diagnosis
Humans ; Tyrosine ; Prospective Studies ; Fatigue/diagnosis ; Fatigue/etiology ; Machine Learning ; Purines ; Pyrimidines

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Skocz do pozycji: 14.

Tytuł:: The PPO family in Nicotiana tabacum is an important regulator to participate in pollination.
Autorzy:: Wei X; School of Engineering, Dali University, Dali, 671000, Yunnan Province, China.
Tao K; School of Life Science, Biocontrol Engineering Research Center of Plant Diseases & Pests, Biocontrol Engineering Research Center of Crop Diseases & Pests, Yunnan University, Kunming, 650091, Yunnan Province, China.
Liu Z; School of Engineering, Dali University, Dali, 671000, Yunnan Province, China.
Qin B; School of Engineering, Dali University, Dali, 671000, Yunnan Province, China.
Su J; School of Life Science, Biocontrol Engineering Research Center of Plant Diseases & Pests, Biocontrol Engineering Research Center of Crop Diseases & Pests, Yunnan University, Kunming, 650091, Yunnan Province, China.
Luo Y; School of Engineering, Dali University, Dali, 671000, Yunnan Province, China.
Zhao C; School of Engineering, Dali University, Dali, 671000, Yunnan Province, China.
Liao J; School of Life Science, Biocontrol Engineering Research Center of Plant Diseases & Pests, Biocontrol Engineering Research Center of Crop Diseases & Pests, Yunnan University, Kunming, 650091, Yunnan Province, China. .
Zhang J; School of Engineering, Dali University, Dali, 671000, Yunnan Province, China. .; Pokaż więcej
Źródło:: BMC plant biology [BMC Plant Biol] 2024 Feb 09; Vol. 24 (1), pp. 102. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:: Journal Article
MeSH Terms:: Nicotiana*/genetics
Pollination*/genetics
Pollen Tube ; Flowers ; Flavonoids/metabolism ; Purines/metabolism

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Skocz do pozycji: 15.

Tytuł:: Comparative overall survival of CDK4/6 inhibitors in combination with endocrine therapy in advanced breast cancer.
Autorzy:: Kappel C; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Elliott MJ; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Kumar V; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Nadler MB; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Desnoyers A; Hôpital Charles-Lemoyne, Greenfield Park, QC, Canada.
Amir E; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada. .; Princess Margaret Cancer Centre, 610 University Ave, 700U, 7-721, Toronto, ON, M5G 2M9, Canada. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 07; Vol. 14 (1), pp. 3129. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:: Journal Article; Meta-Analysis; Systematic Review
MeSH Terms:: Antineoplastic Combined Chemotherapy Protocols*/adverse effects
Breast Neoplasms*/drug therapy
Female ; Humans ; Aminopyridines ; Benzimidazoles ; Cyclin-Dependent Kinase 4 ; Cyclin-Dependent Kinase 6 ; Cyclin-Dependent Kinase Inhibitor Proteins ; Neutropenia/chemically induced ; Purines ; Clinical Trials, Phase III as Topic ; Randomized Controlled Trials as Topic

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Skocz do pozycji: 16.

Tytuł:: Purine Metabolism Dysfunctions: Experimental Methods of Detection and Diagnostic Potential.
Autorzy:: Cicero AFG; Cardiovascular Internal Medicine Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, 40138 Bologna, Italy.; Hypertension and Cardiovascular Risk Research Group, Medical and Surgical Sciences Department, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.
Fogacci F; Hypertension and Cardiovascular Risk Research Group, Medical and Surgical Sciences Department, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.
Di Micoli V; Medical and Surgical Sciences Department, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.
Angeloni C; Department for Life Quality Studies, Alma Mater Studiorum University of Bologna, 47921 Rimini, Italy.
Giovannini M; Hypertension and Cardiovascular Risk Research Group, Medical and Surgical Sciences Department, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.
Borghi C; Cardiovascular Internal Medicine Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, 40138 Bologna, Italy.; Hypertension and Cardiovascular Risk Research Group, Medical and Surgical Sciences Department, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 10; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 10.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Uric Acid*/metabolism
Purines*/metabolism
Animals ; Humans ; Adenine ; Guanine/metabolism ; Xanthine Dehydrogenase/metabolism ; Mammals/metabolism

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Skocz do pozycji: 17.

Tytuł:: Reversine ameliorates hallmarks of cellular senescence in human skeletal myoblasts via reactivation of autophagy.
Autorzy:: Rajabian N; Department of Chemical and Biological Engineering, University at Buffalo, State University of New York, Amherst, New York, USA.
Choudhury D; Department of Chemical and Biological Engineering, University at Buffalo, State University of New York, Amherst, New York, USA.
Ikhapoh I; Department of Chemical and Biological Engineering, University at Buffalo, State University of New York, Amherst, New York, USA.
Saha S; Department of Biomedical Engineering, University at Buffalo, State University of New York, Amherst, New York, USA.
Kalyankar AS; Department of Biomedical Engineering, University at Buffalo, State University of New York, Amherst, New York, USA.
Mehrotra P; Department of Chemical and Biological Engineering, University at Buffalo, State University of New York, Amherst, New York, USA.
Shahini A; Department of Chemical and Biological Engineering, University at Buffalo, State University of New York, Amherst, New York, USA.
Breed K; Department of Chemical and Biological Engineering, University at Buffalo, State University of New York, Amherst, New York, USA.
Andreadis ST; Department of Chemical and Biological Engineering, University at Buffalo, State University of New York, Amherst, New York, USA.; Department of Biomedical Engineering, University at Buffalo, State University of New York, Amherst, New York, USA.; Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo, State University of New York, Amherst, New York, USA.; Cell, Gene and Tissue Engineering (CGTE) Center, School of Engineering and Applied Sciences, University at Buffalo, State University of New York, Amherst, New York, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Mar; Vol. 22 (3), pp. e13764. Date of Electronic Publication: 2023 Jan 10.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Cellular Senescence*/drug effects
Morpholines*/pharmacology
Purines*/pharmacology
Protein Kinase Inhibitors*/pharmacology
Myoblasts, Skeletal*/drug effects
Myoblasts, Skeletal*/physiology
Autophagy*/drug effects
Muscle Development*/drug effects
Humans ; Insulin/metabolism ; AMP-Activated Protein Kinase Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/drug effects ; Glycolysis/drug effects ; Citric Acid Cycle/drug effects ; Insulin Resistance ; Cells, Cultured

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Skocz do pozycji: 18.

Tytuł:: Synthesis of 6-Alkynylated Purine-Containing DNA via On-Column Sonogashira Coupling and Investigation of Their Base-Pairing Properties.
Autorzy:: Okamura H; Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Miyagi, Japan.; Department of Chemistry, Graduate School of Science, Tohoku University, 6-3 Aramaki Aza-Aoba, Aoba-ku, Sendai 980-8577, Miyagi, Japan.
Trinh GH; Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Miyagi, Japan.; Department of Chemistry, Graduate School of Science, Tohoku University, 6-3 Aramaki Aza-Aoba, Aoba-ku, Sendai 980-8577, Miyagi, Japan.
Dong Z; Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Miyagi, Japan.; Department of Chemistry, Graduate School of Science, Tohoku University, 6-3 Aramaki Aza-Aoba, Aoba-ku, Sendai 980-8577, Miyagi, Japan.
Fan W; Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Miyagi, Japan.; Department of Chemistry, Graduate School of Science, Tohoku University, 6-3 Aramaki Aza-Aoba, Aoba-ku, Sendai 980-8577, Miyagi, Japan.
Nagatsugi F; Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Miyagi, Japan.; Department of Chemistry, Graduate School of Science, Tohoku University, 6-3 Aramaki Aza-Aoba, Aoba-ku, Sendai 980-8577, Miyagi, Japan.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Feb 13; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 13.
Typ publikacji:: Journal Article
MeSH Terms:: DNA*/chemistry
Purines*
Base Pairing

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Skocz do pozycji: 19.

Tytuł:: Activation of Purine Biosynthesis Suppresses the Sensitivity of E. coli gmhA Mutant to Antibiotics.
Autorzy:: Seregina TA; Engelhardt Institute of Molecular Biology, Russian Academy of Science, 119991 Moscow, Russia.
Petrushanko IY; Engelhardt Institute of Molecular Biology, Russian Academy of Science, 119991 Moscow, Russia.
Zaripov PI; Engelhardt Institute of Molecular Biology, Russian Academy of Science, 119991 Moscow, Russia.
Shakulov RS; Engelhardt Institute of Molecular Biology, Russian Academy of Science, 119991 Moscow, Russia.
A Sklyarova S; Engelhardt Institute of Molecular Biology, Russian Academy of Science, 119991 Moscow, Russia.
Mitkevich VA; Engelhardt Institute of Molecular Biology, Russian Academy of Science, 119991 Moscow, Russia.
Makarov AA; Engelhardt Institute of Molecular Biology, Russian Academy of Science, 119991 Moscow, Russia.
Mironov AS; Engelhardt Institute of Molecular Biology, Russian Academy of Science, 119991 Moscow, Russia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 08; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 08.
Typ publikacji:: Journal Article
MeSH Terms:: Escherichia coli*/metabolism
Escherichia coli Proteins*/metabolism
Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/metabolism ; NADP/metabolism ; Purines/pharmacology ; Purines/metabolism ; Heptoses/chemistry ; Heptoses/metabolism ; Glutathione/metabolism ; Pentose Phosphate Pathway

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Skocz do pozycji: 20.

Tytuł:: Infrared Spectral Signatures of Nucleobases in Interstellar Ices I: Purines.
Autorzy:: Rosa, Caroline Antunes (AUTHOR)
Bergantini, Alexandre (AUTHOR)
Herczku, Péter (AUTHOR)
Mifsud, Duncan V. (AUTHOR)
Lakatos, Gergő (AUTHOR)
Kovács, Sándor T. S. (AUTHOR)
Sulik, Béla (AUTHOR)
Juhász, Zoltán (AUTHOR)
Ioppolo, Sergio (AUTHOR)
Quitián-Lara, Heidy M. (AUTHOR)
Mason, Nigel J. (AUTHOR)
Lage, Claudia (AUTHOR); Pokaż więcej
Źródło:: Life (2075-1729). Nov2023, Vol. 13 Issue 11, p2208. 15p.

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