Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""PYRROLIDINONES"" wg kryterium: Temat


Tytuł :
Reusable fibrous adsorbent prepared via Co-radiation induced graft polymerization for iodine adsorption.
Autorzy :
Ye F; Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Huang C; Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China; School of Petrochemical Engineering, Changzhou University, Changzhou, 213164, China.
Jiang X; Jining University, Qufu, 273155, China.
He W; Qilu Institute of Technology, Jinan, 250200, China.
Gao X; Qilu Institute of Technology, Jinan, 250200, China.
Ma L; Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Ao J; Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Xu L; Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.
Wang Z; Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.
Li Q; Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.
Li J; Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.
Ma H; Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China. Electronic address: .
Pokaż więcej
Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Oct 15; Vol. 203, pp. 111021. Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
Gamma Rays*
Air Pollutants, Radioactive/*analysis
Green Chemistry Technology/*methods
Iodine/*analysis
Polypropylenes/*chemistry
Pyrrolidinones/*chemistry
Adsorption ; Humans ; Kinetics ; Polymerization ; Polypropylenes/radiation effects ; Pyrrolidinones/radiation effects ; Surface Properties
Czasopismo naukowe
Tytuł :
Erlotinib plus tivantinib versus erlotinib alone in patients with previously treated stage IIIb/IV non-small-cell lung cancer: A meta-analysis based on randomized controlled trials.
Autorzy :
Deng H; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University.; Jiangxi Medical College, Nanchang University.
Wang L; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University.; Jiangxi Medical College, Nanchang University.
Chen X; Jiangxi Medical College, Nanchang University.; Department of Oncology, The second affiliated hospital of Nanchang University, Nanchang, China.
Zhang S; Jiangxi Medical College, Nanchang University.; Department of Oncology, The second affiliated hospital of Nanchang University, Nanchang, China.
Yi F; Department of Oncology, The second affiliated hospital of Nanchang University, Nanchang, China.
Wei Y; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University.
Zhang W; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University.
Pokaż więcej
Źródło :
Medicine [Medicine (Baltimore)] 2020 Jun 19; Vol. 99 (25), pp. e20596.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Antineoplastic Agents/*administration & dosage
Antineoplastic Agents/*therapeutic use
Carcinoma, Non-Small-Cell Lung/*drug therapy
Erlotinib Hydrochloride/*administration & dosage
Lung Neoplasms/*drug therapy
Pyrrolidinones/*administration & dosage
Quinolines/*administration & dosage
Antineoplastic Agents/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Erlotinib Hydrochloride/adverse effects ; Humans ; Progression-Free Survival ; Pyrrolidinones/adverse effects ; Quinolines/adverse effects ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł :
Novel pyrrolidinone derivative lacks claimed histamine H 3 receptor stimulation in receptor binding and functional studies.
Autorzy :
Reiner D; Heinrich Heine University Düsseldorf, Institute of Pharmaceutical and Medicinal Chemistry, Universitaetsstr. 1, 40225, Duesseldorf, Germany.
Zivkovic A; Heinrich Heine University Düsseldorf, Institute of Pharmaceutical and Medicinal Chemistry, Universitaetsstr. 1, 40225, Duesseldorf, Germany.
Labeeuw O; Bioprojet Biotech, 4 Rue du Chesnay Beauregard, 35760, Saint-Grégoire, France.
Krief S; Bioprojet Biotech, 4 Rue du Chesnay Beauregard, 35760, Saint-Grégoire, France.
Capet M; Bioprojet Biotech, 4 Rue du Chesnay Beauregard, 35760, Saint-Grégoire, France.
Stark H; Heinrich Heine University Düsseldorf, Institute of Pharmaceutical and Medicinal Chemistry, Universitaetsstr. 1, 40225, Duesseldorf, Germany. Electronic address: .
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2020 Apr 01; Vol. 191, pp. 112150. Date of Electronic Publication: 2020 Feb 14.
Typ publikacji :
Journal Article
MeSH Terms :
Pyrrolidinones/*pharmacology
Receptors, Histamine H3/*metabolism
Dose-Response Relationship, Drug ; Fluorescence Polarization ; HEK293 Cells ; Humans ; Molecular Structure ; Protein Binding/drug effects ; Pyrrolidinones/chemical synthesis ; Pyrrolidinones/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Substituted 1-methyl-4-phenylpyrrolidin-2-ones - Fragment-based design of N-methylpyrrolidone-derived bromodomain inhibitors.
Autorzy :
Hilton-Proctor JP; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria, Australia.
Ilyichova O; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria, Australia.
Zheng Z; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria, Australia.
Jennings IG; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria, Australia.
Johnstone RW; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, Victoria, Australia; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.
Shortt J; Blood Cancer Therapeutics Laboratory, School of Clinical Sciences at Monash Health, Monash University, 246 Clayton Road, Clayton, Victoria, Australia; Monash Haematology, Monash Health, 246 Clayton Road, Clayton, Victoria, Australia.
Mountford SJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria, Australia.
Scanlon MJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria, Australia.
Thompson PE; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria, Australia. Electronic address: .
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2020 Apr 01; Vol. 191, pp. 112120. Date of Electronic Publication: 2020 Feb 12.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Cell Cycle Proteins/*antagonists & inhibitors
Pyrrolidinones/*pharmacology
Transcription Factors/*antagonists & inhibitors
Cell Cycle Proteins/metabolism ; Crystallography, X-Ray ; Dose-Response Relationship, Drug ; Fluorescence Resonance Energy Transfer ; Humans ; Models, Molecular ; Molecular Structure ; Pyrrolidinones/chemistry ; Structure-Activity Relationship ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Microtubule disrupting agent-mediated inhibition of cancer cell growth is associated with blockade of autophagic flux and simultaneous induction of apoptosis.
Autorzy :
Hasanain M; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, India.
Sahai R; Electron Microscopy Unit, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Pandey P; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Maheshwari M; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Choyal K; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Gandhi D; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Singh A; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Singh K; Electron Microscopy Unit, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Mitra K; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, India.; Electron Microscopy Unit, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Datta D; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, India.
Sarkar J; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, India.
Pokaż więcej
Źródło :
Cell proliferation [Cell Prolif] 2020 Apr; Vol. 53 (4), pp. e12749. Date of Electronic Publication: 2020 Mar 13.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Cell Proliferation/*drug effects
Neoplasms/*drug therapy
Pyrrolidinones/*therapeutic use
Tubulin Modulators/*therapeutic use
Animals ; Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Autophagy/drug effects ; Cell Line, Tumor ; Female ; Humans ; Mice ; Mice, Nude ; Microtubules/drug effects ; Microtubules/metabolism ; Microtubules/pathology ; Neoplasms/metabolism ; Neoplasms/pathology ; Pyrrolidinones/pharmacology ; Tubulin Modulators/pharmacology
Czasopismo naukowe
Tytuł :
Effect of heat shock protein 70 modulators on the development of morphine analgesic tolerance in rats.
Autorzy :
Qin W; Department of Pharmacy, China-Japan Friendship Hospital.
Zhang L; Department of Pharmacy, China-Japan Friendship Hospital.
Tang K; Department of Pharmacy, China-Japan Friendship Hospital.
Zhao L; Department of Pharmacy, China-Japan Friendship Hospital.
Mao M; Department of Pharmacy, China-Japan Friendship Hospital.
Wang Y; Department of Pharmacy, Cancer Hospital Chinese Academy of Medical Sciences.
Liang J; Department of Molecular and Cellular Pharmacology, Peking University School of Pharmaceutical Sciences, Beijing, China.
Zhang X; Department of Pharmacy, China-Japan Friendship Hospital.
Li P; Department of Pharmacy, China-Japan Friendship Hospital.
Pokaż więcej
Źródło :
Behavioural pharmacology [Behav Pharmacol] 2020 Apr; Vol. 31 (2&3), pp. 179-185.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Benzhydryl Compounds/*pharmacology
Drug Tolerance/*physiology
HSP70 Heat-Shock Proteins/*metabolism
Pyrrolidinones/*pharmacology
Analgesics/pharmacology ; Analgesics, Opioid/pharmacology ; Animals ; Benzhydryl Compounds/metabolism ; Brain/metabolism ; Female ; Male ; Morphine/pharmacology ; Periaqueductal Gray/metabolism ; Pyrrolidinones/metabolism ; Rats ; Rats, Sprague-Dawley ; Receptors, Opioid, mu/metabolism
Czasopismo naukowe
Tytuł :
Effect of a calcium hydroxide-based intracanal medicament containing N-2-methyl pyrrolidone as a vehicle against Enterococcus faecalis biofilm.
Autorzy :
Kim T; Chonbuk National University, School of Dentistry and Institute of Oral Bioscience, Department of Conservative Dentistry, Jeonju, Korea.
Kim MA; Chonbuk National University, School of Dentistry and Institute of Oral Bioscience, Department of Conservative Dentistry, Jeonju, Korea.
Hwang YC; Chonnam National University, School of Dentistry, Department of Conservative Dentistry, Gwangju, Korea.
Rosa V; National University of Singapore, Faculty of Dentistry, Discipline of Oral Sciences, Singapore.
Del Fabbro M; Università degli Studi di Milano, Dipartimento di Scienze Biomediche, Chirurgiche e Odontoiatriche, Milano, Italia.; IRCCS Istituto Ortopedico Galeazzi, Milano, Italia.
Min KS; Chonbuk National University, School of Dentistry and Institute of Oral Bioscience, Department of Conservative Dentistry, Jeonju, Korea.; Chonbuk National University, Research Institute of Clinical Medicine, Jeonju, Korea.; Chonbuk National University Hospital, Biomedical Research Institute, Jeonju, Korea.
Pokaż więcej
Źródło :
Journal of applied oral science : revista FOB [J Appl Oral Sci] 2020 Mar 27; Vol. 28, pp. e20190516. Date of Electronic Publication: 2020 Mar 27 (Print Publication: 2020).
Typ publikacji :
Comparative Study; Evaluation Study; Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Biofilms/*drug effects
Calcium Hydroxide/*pharmacology
Enterococcus faecalis/*drug effects
Pyrrolidinones/*pharmacology
Root Canal Irrigants/*pharmacology
Analysis of Variance ; Animals ; Calcium Chloride/chemistry ; Calcium Chloride/pharmacology ; Calcium Hydroxide/chemistry ; Cattle ; Colony Count, Microbial ; Drug Combinations ; Materials Testing ; Microscopy, Confocal ; Microscopy, Electron, Scanning ; Potassium Chloride/chemistry ; Potassium Chloride/pharmacology ; Pyrrolidinones/chemistry ; Reproducibility of Results ; Root Canal Irrigants/chemistry ; Sodium Bicarbonate/chemistry ; Sodium Bicarbonate/pharmacology ; Sodium Chloride/chemistry ; Sodium Chloride/pharmacology ; Statistics, Nonparametric
Czasopismo naukowe
Tytuł :
Pharmacological Profile of the Novel Antiepileptic Drug Candidate Padsevonil: Characterization in Rodent Seizure and Epilepsy Models.
Autorzy :
Leclercq K; UCB Pharma, Neurosciences Therapeutic Area, Braine l'Alleud, Belgium .
Matagne A; UCB Pharma, Neurosciences Therapeutic Area, Braine l'Alleud, Belgium.
Provins L; UCB Pharma, Neurosciences Therapeutic Area, Braine l'Alleud, Belgium.
Klitgaard H; UCB Pharma, Neurosciences Therapeutic Area, Braine l'Alleud, Belgium.
Kaminski RM; UCB Pharma, Neurosciences Therapeutic Area, Braine l'Alleud, Belgium.
Pokaż więcej
Źródło :
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2020 Jan; Vol. 372 (1), pp. 11-20. Date of Electronic Publication: 2019 Oct 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anticonvulsants/*therapeutic use
Epilepsy/*drug therapy
Imidazoles/*therapeutic use
Pyrrolidinones/*therapeutic use
Seizures/*drug therapy
Thiadiazoles/*therapeutic use
Amygdala/drug effects ; Amygdala/physiopathology ; Animals ; Anticonvulsants/adverse effects ; Anticonvulsants/pharmacology ; Drug Evaluation, Preclinical ; Female ; Imidazoles/adverse effects ; Imidazoles/pharmacology ; Kindling, Neurologic ; Male ; Maximum Tolerated Dose ; Mice ; Mice, Inbred C57BL ; Mice, Inbred DBA ; Pyrrolidinones/adverse effects ; Pyrrolidinones/pharmacology ; Rats ; Rats, Sprague-Dawley ; Thiadiazoles/adverse effects ; Thiadiazoles/pharmacology
Czasopismo naukowe
Tytuł :
Synthesis and biological evaluation of new multi-target 3-(1H-indol-3-yl)pyrrolidine-2,5-dione derivatives with potential antidepressant effect.
Autorzy :
Wróbel MZ; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Street, 02-097, Warszawa, Poland. Electronic address: .
Chodkowski A; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Street, 02-097, Warszawa, Poland.
Herold F; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Street, 02-097, Warszawa, Poland.
Marciniak M; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Street, 02-097, Warszawa, Poland.
Dawidowski M; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Street, 02-097, Warszawa, Poland.
Siwek A; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688, Kraków, Poland.
Starowicz G; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688, Kraków, Poland.
Stachowicz K; Department of Neurobiology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, 31-343, Kraków, Poland.
Szewczyk B; Department of Neurobiology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, 31-343, Kraków, Poland.
Nowak G; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688, Kraków, Poland; Department of Neurobiology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, 31-343, Kraków, Poland.
Belka M; Department of Pharmaceutical Chemistry, Medical University of Gdańsk, 80-416, Gdańsk, Poland.
Bączek T; Department of Pharmaceutical Chemistry, Medical University of Gdańsk, 80-416, Gdańsk, Poland.
Satała G; Department of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, 31-343, Kraków, Poland.
Bojarski AJ; Department of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, 31-343, Kraków, Poland.
Turło J; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Street, 02-097, Warszawa, Poland.
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2019 Dec 01; Vol. 183, pp. 111736. Date of Electronic Publication: 2019 Sep 26.
Typ publikacji :
Journal Article
MeSH Terms :
Antidepressive Agents*/chemical synthesis
Antidepressive Agents*/pharmacology
Indoles*/chemical synthesis
Indoles*/pharmacology
Pyrrolidinones*/chemical synthesis
Pyrrolidinones*/pharmacology
Animals ; CHO Cells ; Cricetulus ; HEK293 Cells ; Humans ; Male ; Mice ; Receptors, Serotonin/metabolism ; Serotonin Uptake Inhibitors/chemical synthesis ; Serotonin Uptake Inhibitors/metabolism ; Serotonin Uptake Inhibitors/pharmacology
Czasopismo naukowe
Tytuł :
Toxicity of the herbicide flurochloridone to the aquatic plants Ceratophyllum demersum and Lemna minor.
Autorzy :
Zhou J; National Field Station of Freshwater Ecosystem in Liangzi Lake, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China. .
Wu Z; National Field Station of Freshwater Ecosystem in Liangzi Lake, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China. .
Yu D; National Field Station of Freshwater Ecosystem in Liangzi Lake, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China.
Yang L; National Field Station of Freshwater Ecosystem in Liangzi Lake, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China.
Pokaż więcej
Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2020 Feb; Vol. 27 (4), pp. 3923-3932. Date of Electronic Publication: 2019 Dec 10.
Typ publikacji :
Journal Article
MeSH Terms :
Araceae*/drug effects
Herbicides*/toxicity
Pyrrolidinones*/toxicity
Chlorophyll A
Czasopismo naukowe
Tytuł :
A selective androgen receptor modulator SARM-2f activates androgen receptor, increases lean body mass, and suppresses blood lipid levels in cynomolgus monkeys.
Autorzy :
Morimoto M; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan.
Yamaoka M; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan.
Hara T; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan.
Pokaż więcej
Źródło :
Pharmacology research & perspectives [Pharmacol Res Perspect] 2020 Feb; Vol. 8 (1), pp. e00563.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lipid Metabolism/*drug effects
Pyrrolidinones/*administration & dosage
Receptors, Androgen/*metabolism
Administration, Oral ; Animals ; Body Mass Index ; Body Weight/drug effects ; COS Cells ; Chlorocebus aethiops ; Female ; Humans ; Macaca fascicularis ; Male ; Pyrrolidinones/pharmacokinetics ; Rats
Czasopismo naukowe
Tytuł :
Synthesis of novel N-vinylpyrrolidone/acrylic acid nanoparticles as drug delivery carriers of cisplatin to cancer cells.
Autorzy :
Pornpitchanarong C; Pharmaceutical Development of Green Innovations Group (PDGIG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand.
Rojanarata T; Pharmaceutical Development of Green Innovations Group (PDGIG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand.
Opanasopit P; Pharmaceutical Development of Green Innovations Group (PDGIG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand.
Ngawhirunpat T; Pharmaceutical Development of Green Innovations Group (PDGIG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand.
Patrojanasophon P; Pharmaceutical Development of Green Innovations Group (PDGIG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand. Electronic address: .
Pokaż więcej
Źródło :
Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2020 Jan 01; Vol. 185, pp. 110566. Date of Electronic Publication: 2019 Oct 07.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Delivery Systems*
Acrylates/*chemical synthesis
Cisplatin/*administration & dosage
Drug Carriers/*chemistry
Nanoparticles/*chemistry
Pyrrolidinones/*chemical synthesis
Acrylates/chemistry ; Apoptosis/drug effects ; Cell Death/drug effects ; Cell Line ; Cell Line, Tumor ; Cisplatin/pharmacology ; Drug Liberation ; Humans ; Nanoparticles/ultrastructure ; Particle Size ; Pyrrolidinones/chemistry ; Static Electricity
Czasopismo naukowe
Tytuł :
A new human cadaver model for laparoscopic training using N-vinyl-2-pyrrolidone: a feasibility study.
Autorzy :
Nagase M; Department of Anatomy, Kyorin University Faculty of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611, Japan. .
Kimoto Y; Department of Anatomy, Kyorin University Faculty of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611, Japan.
Sunami E; Department of Surgery, Kyorin University Faculty of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611, Japan.
Matsumura G; Department of Anatomy, Kyorin University Faculty of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611, Japan.
Pokaż więcej
Źródło :
Anatomical science international [Anat Sci Int] 2020 Jan; Vol. 95 (1), pp. 156-164. Date of Electronic Publication: 2019 Jul 26.
Typ publikacji :
Journal Article
MeSH Terms :
Cadaver*
Models, Anatomic*
Pyrrolidinones*
Anatomy/*education
Education, Medical/*methods
Laparoscopy/*education
Feasibility Studies ; Humans
Czasopismo naukowe
Tytuł :
Pharmacological Profile of the Novel Antiepileptic Drug Candidate Padsevonil: Interactions with Synaptic Vesicle 2 Proteins and the GABA A Receptor.
Autorzy :
Wood M; UCB Pharma, Neurosciences Therapeutic Area, Braine l'Alleud, Belgium.
Daniels V; UCB Pharma, Neurosciences Therapeutic Area, Braine l'Alleud, Belgium.
Provins L; UCB Pharma, Neurosciences Therapeutic Area, Braine l'Alleud, Belgium.
Wolff C; UCB Pharma, Neurosciences Therapeutic Area, Braine l'Alleud, Belgium.
Kaminski RM; UCB Pharma, Neurosciences Therapeutic Area, Braine l'Alleud, Belgium.
Gillard M; UCB Pharma, Neurosciences Therapeutic Area, Braine l'Alleud, Belgium .
Pokaż więcej
Źródło :
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2020 Jan; Vol. 372 (1), pp. 1-10. Date of Electronic Publication: 2019 Oct 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anticonvulsants/*pharmacokinetics
GABA Agonists/*pharmacokinetics
Imidazoles/*pharmacokinetics
Membrane Glycoproteins/*metabolism
Nerve Tissue Proteins/*metabolism
Pyrrolidinones/*pharmacokinetics
Receptors, GABA-A/*metabolism
Thiadiazoles/*pharmacokinetics
Animals ; Anticonvulsants/chemistry ; COS Cells ; Chlorocebus aethiops ; GABA Agonists/chemistry ; HEK293 Cells ; Humans ; Imidazoles/chemistry ; Kinetics ; Male ; Mice ; Mice, Inbred C57BL ; Protein Binding ; Pyrrolidinones/chemistry ; Rats ; Rats, Sprague-Dawley ; Thiadiazoles/chemistry
Czasopismo naukowe
Tytuł :
Clinical radiotherapy application of N-vinylpyrrolidone-containing 3D polymer gel dosimeters with remote external MR-reading.
Autorzy :
Kozicki M; Department of Mechanical Engineering, Informatics and Chemistry of Polymer Materials, Lodz University of Technology, Lodz, Poland; GeVero Co., Lodz, Poland(1). Electronic address: .
Berg A; High Field MR-Center, Medical University of Vienna, Austria.
Maras P; Medical Physics Department, Copernicus Hospital, Lodz, Poland.
Jaszczak M; Department of Mechanical Engineering, Informatics and Chemistry of Polymer Materials, Lodz University of Technology, Lodz, Poland.
Dudek M; Institute of Materials Science and Engineering, Lodz University of Technology, Lodz, Poland.
Pokaż więcej
Źródło :
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) [Phys Med] 2020 Jan; Vol. 69, pp. 134-146. Date of Electronic Publication: 2020 Jan 03.
Typ publikacji :
Journal Article
MeSH Terms :
Magnetic Resonance Imaging*
Pyrrolidinones*
Lung Neoplasms/*diagnostic imaging
Lung Neoplasms/*radiotherapy
Radiometry/*instrumentation
Radiotherapy/*methods
Calibration ; Gelatin/chemistry ; Humans ; Imaging, Three-Dimensional ; Polymers ; Radiometry/methods ; Software
Czasopismo naukowe
Tytuł :
Efficacy, retention, and safety of brivaracetam in adult patients with genetic generalized epilepsy.
Autorzy :
Fonseca E; Epilepsy Unit, Neurology Department, Hospital Vall d'Hebron, Department of Medicine, Universitat Autònoma de Barcelona, Pg. Vall d'Hebron, 119-129, 08035 Barcelona, Spain. Electronic address: .
Guzmán L; Neurophysiology Department, Hospital Vall d'Hebron, Department of Medicine, Universitat Autònoma de Barcelona, Pg. Vall d'Hebron, 119-129, 08035 Barcelona, Spain.
Quintana M; Epilepsy Unit, Neurology Department, Hospital Vall d'Hebron, Department of Medicine, Universitat Autònoma de Barcelona, Pg. Vall d'Hebron, 119-129, 08035 Barcelona, Spain. Electronic address: .
Abraira L; Epilepsy Unit, Neurology Department, Hospital Vall d'Hebron, Department of Medicine, Universitat Autònoma de Barcelona, Pg. Vall d'Hebron, 119-129, 08035 Barcelona, Spain. Electronic address: .
Santamarina E; Epilepsy Unit, Neurology Department, Hospital Vall d'Hebron, Department of Medicine, Universitat Autònoma de Barcelona, Pg. Vall d'Hebron, 119-129, 08035 Barcelona, Spain. Electronic address: .
Salas-Puig X; Epilepsy Unit, Neurology Department, Hospital Vall d'Hebron, Department of Medicine, Universitat Autònoma de Barcelona, Pg. Vall d'Hebron, 119-129, 08035 Barcelona, Spain.
Toledo M; Epilepsy Unit, Neurology Department, Hospital Vall d'Hebron, Department of Medicine, Universitat Autònoma de Barcelona, Pg. Vall d'Hebron, 119-129, 08035 Barcelona, Spain. Electronic address: .
Pokaż więcej
Źródło :
Epilepsy & behavior : E&B [Epilepsy Behav] 2020 Jan; Vol. 102, pp. 106657. Date of Electronic Publication: 2019 Nov 12.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Medication Adherence*/psychology
Anticonvulsants/*therapeutic use
Epilepsy, Generalized/*drug therapy
Epilepsy, Generalized/*genetics
Pyrrolidinones/*therapeutic use
Adolescent ; Adult ; Anticonvulsants/adverse effects ; Electroencephalography/drug effects ; Electroencephalography/methods ; Epilepsy, Generalized/psychology ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Pyrrolidinones/adverse effects ; Retrospective Studies ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Economic Value of Adjunctive Brivaracetam Treatment Strategy for Focal Onset Seizures in Finland.
Autorzy :
Väätäinen S; ESiOR Oy, Kuopio, Finland.
Soini E; ESiOR Oy, Kuopio, Finland. .
Peltola J; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Neurology, Tampere University Hospital, Tampere, Finland.
Charokopou M; UCB Pharma Belgium, Brussels, Belgium.
Taiha M; UCB Pharma Oy Finland, Espoo, Finland.
Kälviäinen R; Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.; Epilepsy Center, Neurocenter, Kuopio University Hospital, Member of the European Reference Network for Rare and Complex Epilepsies EpiCARE, Kuopio, Finland.
Pokaż więcej
Źródło :
Advances in therapy [Adv Ther] 2020 Jan; Vol. 37 (1), pp. 477-500. Date of Electronic Publication: 2019 Dec 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Quality-Adjusted Life Years*
Anticonvulsants/*economics
Epilepsy/*drug therapy
Pyrrolidinones/*economics
Seizures/*drug therapy
Adolescent ; Adult ; Anticonvulsants/therapeutic use ; Bayes Theorem ; Cost-Benefit Analysis ; Drug Therapy, Combination ; Epilepsy/economics ; Female ; Finland ; Humans ; Pyrrolidinones/therapeutic use ; Seizures/economics ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Synthesis and elaboration of N-methylpyrrolidone as an acetamide fragment substitute in bromodomain inhibition.
Autorzy :
Hilton-Proctor JP; Medicinal Chemistry, Monash Institute of Pharmaceutical Science, Monash University, 381 Royal Parade, Parkville, Victoria, Australia.
Ilyichova O; Medicinal Chemistry, Monash Institute of Pharmaceutical Science, Monash University, 381 Royal Parade, Parkville, Victoria, Australia.
Zheng Z; Medicinal Chemistry, Monash Institute of Pharmaceutical Science, Monash University, 381 Royal Parade, Parkville, Victoria, Australia.
Jennings IG; Medicinal Chemistry, Monash Institute of Pharmaceutical Science, Monash University, 381 Royal Parade, Parkville, Victoria, Australia.
Johnstone RW; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, Victoria, Australia; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.
Shortt J; Blood Cancer Therapeutics Laboratory, School of Clinical Sciences at Monash Health, Monash University, 246 Clayton Road, Clayton, Victoria, Australia; Monash Haematology, Monash Health, 246 Clayton Road, Clayton, Victoria, Australia.
Mountford SJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Science, Monash University, 381 Royal Parade, Parkville, Victoria, Australia.
Scanlon MJ; Medicinal Chemistry, Monash Institute of Pharmaceutical Science, Monash University, 381 Royal Parade, Parkville, Victoria, Australia.
Thompson PE; Medicinal Chemistry, Monash Institute of Pharmaceutical Science, Monash University, 381 Royal Parade, Parkville, Victoria, Australia. Electronic address: .
Pokaż więcej
Źródło :
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2019 Dec 15; Vol. 27 (24), pp. 115157. Date of Electronic Publication: 2019 Oct 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Design*
Cell Cycle Proteins/*chemistry
Pyrrolidinones/*chemical synthesis
Transcription Factors/*chemistry
Binding Sites ; Cell Cycle Proteins/metabolism ; Crystallography, X-Ray ; Fluorescence Resonance Energy Transfer ; Gene Expression Regulation/drug effects ; Humans ; Models, Molecular ; Molecular Structure ; Protein Binding ; Protein Conformation ; Pyrrolidinones/chemistry ; Structure-Activity Relationship ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Adjunctive brivaracetam in focal and generalized epilepsies: A single-center open-label prospective study in patients with psychiatric comorbidities and intellectual disability.
Autorzy :
Foo EC; Department of Neurology, Leeds Teaching Hospitals, Leeds, United Kingdom. Electronic address: .
Geldard J; Department of Neurology, Leeds Teaching Hospitals, Leeds, United Kingdom.
Peacey C; Department of Neurology, Leeds Teaching Hospitals, Leeds, United Kingdom.
Wright E; Department of Neurology, Leeds Teaching Hospitals, Leeds, United Kingdom.
Eltayeb K; Department of Neurology, Leeds Teaching Hospitals, Leeds, United Kingdom.
Maguire M; Department of Neurology, Leeds Teaching Hospitals, Leeds, United Kingdom.
Pokaż więcej
Źródło :
Epilepsy & behavior : E&B [Epilepsy Behav] 2019 Oct; Vol. 99, pp. 106505. Date of Electronic Publication: 2019 Sep 04.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Behavioral Symptoms*/chemically induced
Behavioral Symptoms*/epidemiology
Intellectual Disability*/epidemiology
Mental Disorders*/chemically induced
Mental Disorders*/epidemiology
Anticonvulsants/*pharmacology
Epilepsies, Partial/*drug therapy
Epilepsy, Generalized/*drug therapy
Levetiracetam/*pharmacology
Pyrrolidinones/*pharmacology
Adolescent ; Adult ; Aged ; Anticonvulsants/administration & dosage ; Anticonvulsants/adverse effects ; Comorbidity ; Drug Therapy, Combination ; Epilepsies, Partial/epidemiology ; Epilepsy, Generalized/epidemiology ; Female ; Humans ; Levetiracetam/administration & dosage ; Levetiracetam/adverse effects ; Male ; Middle Aged ; Prospective Studies ; Pyrrolidinones/administration & dosage ; Pyrrolidinones/adverse effects ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Recent advances in the pharmacotherapy of epilepsy: brivaracetam and perampanel as broad-spectrum antiseizure drugs for the treatment of epilepsies and status epilepticus.
Autorzy :
Willems LM; Epilepsy Center Frankfurt Rhine-Main and Department of Neurology, Goethe-University Frankfurt , Frankfurt am Main , Germany.; LOEWE Center for Personalized Translational Epilepsy Research (CePTER), Goethe-University Frankfurt , Frankfurt am Main , Germany.
Bauer S; Epilepsy Center Frankfurt Rhine-Main and Department of Neurology, Goethe-University Frankfurt , Frankfurt am Main , Germany.; LOEWE Center for Personalized Translational Epilepsy Research (CePTER), Goethe-University Frankfurt , Frankfurt am Main , Germany.
Rosenow F; Epilepsy Center Frankfurt Rhine-Main and Department of Neurology, Goethe-University Frankfurt , Frankfurt am Main , Germany.; LOEWE Center for Personalized Translational Epilepsy Research (CePTER), Goethe-University Frankfurt , Frankfurt am Main , Germany.
Strzelczyk A; Epilepsy Center Frankfurt Rhine-Main and Department of Neurology, Goethe-University Frankfurt , Frankfurt am Main , Germany.; LOEWE Center for Personalized Translational Epilepsy Research (CePTER), Goethe-University Frankfurt , Frankfurt am Main , Germany.; Epilepsy Center Hessen and Department of Neurology, Philipps-University Marburg , Marburg (Lahn) , Germany.
Pokaż więcej
Źródło :
Expert opinion on pharmacotherapy [Expert Opin Pharmacother] 2019 Oct; Vol. 20 (14), pp. 1755-1765. Date of Electronic Publication: 2019 Jul 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anticonvulsants/*therapeutic use
Epilepsy/*drug therapy
Pyridones/*therapeutic use
Pyrrolidinones/*therapeutic use
Anticonvulsants/adverse effects ; Anticonvulsants/pharmacokinetics ; Clinical Trials as Topic ; Epilepsy/pathology ; Half-Life ; Humans ; Pyridones/adverse effects ; Pyridones/pharmacokinetics ; Pyrrolidinones/adverse effects ; Pyrrolidinones/pharmacokinetics ; Receptors, AMPA/chemistry ; Receptors, AMPA/metabolism ; Status Epilepticus/drug therapy ; Treatment Outcome
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies