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Tytuł :
Astrocytic palmitoylethanolamide pre-exposure exerts neuroprotective effects in astrocyte-neuron co-cultures from a triple transgenic mouse model of Alzheimer's disease.
Autorzy :
Beggiato S; Department of Life Sciences and Biotechnology, University of Ferrara, Via Borsari, 36-44121 Ferrara, Italy; Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Via dei Vestini, 31-66100 Chieti, Italy.
Cassano T; Department of Clinical and Experimental Medicine, University of Foggia, viale Pinto, 1-71122 Foggia, Italy.
Ferraro L; Department of Life Sciences and Biotechnology, University of Ferrara, Via Borsari, 36-44121 Ferrara, Italy; Department of Clinical and Experimental Medicine, University of Foggia, viale Pinto, 1-71122 Foggia, Italy; IRET Foundation, Via Tolara di Sopra 41 - 40064 Ozzano dell'Emilia, Bologna, Italy; Technopole of Ferrara, LTTA Laboratory for the Technologies for Advanced Therapies, Via Fossato di Mortara 70, 44121 Ferrara, Italy. Electronic address: .
Tomasini MC; Department of Life Sciences and Biotechnology, University of Ferrara, Via Borsari, 36-44121 Ferrara, Italy.
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Źródło :
Life sciences [Life Sci] 2020 Sep 15; Vol. 257, pp. 118037. Date of Electronic Publication: 2020 Jul 02.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*drug effects
Astrocytes/*metabolism
Ethanolamines/*pharmacology
Palmitic Acids/*pharmacology
Alzheimer Disease/drug therapy ; Alzheimer Disease/metabolism ; Amyloid beta-Peptides/metabolism ; Animals ; Cell Survival/drug effects ; Cerebral Cortex/metabolism ; Coculture Techniques ; Disease Models, Animal ; Ethanolamines/metabolism ; Gliosis ; Humans ; Male ; Mice ; Mice, Transgenic ; Microtubule-Associated Proteins ; Neurons/drug effects ; Neuroprotective Agents/pharmacology ; Palmitic Acids/metabolism ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł :
Effect of 3-O-acetylaleuritolic acid from in vitro-cultured Drosera spatulata on cancer cells survival and migration.
Autorzy :
Toton E; Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355, Poznan, Poland. .
Kedziora I; Department of Pharmaceutical Botany, Poznan University of Medical Sciences, Marii Magdaleny 14, 61-861, Poznan, Poland.
Romaniuk-Drapala A; Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355, Poznan, Poland.
Konieczna N; Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355, Poznan, Poland.
Kaczmarek M; Department of Clinical Immunology, Poznan University of Medical Sciences, Rokietnicka 5D, 60-806, Poznan, Poland.
Lisiak N; Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355, Poznan, Poland.
Paszel-Jaworska A; Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355, Poznan, Poland.
Rybska A; Poznan University of Medical Sciences, Poznan, Poland.
Duszynska W; Poznan University of Medical Sciences, Poznan, Poland.
Budzianowski J; Department of Pharmaceutical Botany, Poznan University of Medical Sciences, Marii Magdaleny 14, 61-861, Poznan, Poland.
Rybczynska M; Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355, Poznan, Poland.
Rubis B; Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355, Poznan, Poland.
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Źródło :
Pharmacological reports : PR [Pharmacol Rep] 2020 Feb; Vol. 72 (1), pp. 166-178. Date of Electronic Publication: 2020 Jan 10.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Cell Proliferation/*drug effects
Drosera/*chemistry
Palmitic Acids/*pharmacology
Antineoplastic Agents, Phytogenic/administration & dosage ; Antineoplastic Agents, Phytogenic/isolation & purification ; Autophagy/drug effects ; Cell Movement/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; HT29 Cells ; HeLa Cells ; Humans ; MCF-7 Cells ; Palmitic Acids/administration & dosage ; Palmitic Acids/isolation & purification
Czasopismo naukowe
Tytuł :
First evidence on the role of palmitoylethanolamide in energy homeostasis in fish.
Autorzy :
Gómez-Boronat M; Departamento de Genética, Fisiología y Microbiología, Unidad Docente de Fisiología Animal, Facultad de Biología, Universidad Complutense de Madrid, Madrid, Spain. Electronic address: .
Isorna E; Departamento de Genética, Fisiología y Microbiología, Unidad Docente de Fisiología Animal, Facultad de Biología, Universidad Complutense de Madrid, Madrid, Spain.
Conde-Sieira M; Laboratorio de Fisioloxía Animal, Departamento de Bioloxía Funcional e Ciencias da Saúde, Facultade de Bioloxía and Centro de Investigación Mariña, Universidade de Vigo, Vigo, Spain.
Delgado MJ; Departamento de Genética, Fisiología y Microbiología, Unidad Docente de Fisiología Animal, Facultad de Biología, Universidad Complutense de Madrid, Madrid, Spain.
Soengas JL; Laboratorio de Fisioloxía Animal, Departamento de Bioloxía Funcional e Ciencias da Saúde, Facultade de Bioloxía and Centro de Investigación Mariña, Universidade de Vigo, Vigo, Spain.
de Pedro N; Departamento de Genética, Fisiología y Microbiología, Unidad Docente de Fisiología Animal, Facultad de Biología, Universidad Complutense de Madrid, Madrid, Spain.
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Źródło :
Hormones and behavior [Horm Behav] 2020 Jan; Vol. 117, pp. 104609. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Energy Metabolism/*drug effects
Ethanolamines/*pharmacology
Goldfish/*metabolism
Homeostasis/*drug effects
Palmitic Acids/*pharmacology
Animals ; Body Weight/drug effects ; CLOCK Proteins/genetics ; CLOCK Proteins/metabolism ; Eating/drug effects ; Eating/physiology ; Ethanolamines/administration & dosage ; Gene Expression Regulation/drug effects ; Hypothalamus/drug effects ; Hypothalamus/metabolism ; Injections, Intraperitoneal ; Leptin/metabolism ; Lipid Metabolism/drug effects ; Liver/drug effects ; Liver/metabolism ; Locomotion/drug effects ; Locomotion/physiology ; Palmitic Acids/administration & dosage ; Peroxisome Proliferator-Activated Receptors/genetics ; Peroxisome Proliferator-Activated Receptors/metabolism ; Weight Gain/drug effects
Czasopismo naukowe
Tytuł :
Sodium chromo-glycate and palmitoylethanolamide: A possible strategy to treat mast cell-induced lung inflammation in COVID-19.
Autorzy :
Gigante A; Department of Clinical and Molecular Science, School of Medicine, Università Politecnica delle Marche, Ancona, Italy. Electronic address: .
Aquili A; Department of Clinical and Molecular Science, School of Medicine, Università Politecnica delle Marche, Ancona, Italy.
Farinelli L; Department of Clinical and Molecular Science, School of Medicine, Università Politecnica delle Marche, Ancona, Italy.
Caraffa A; School of Pharmacy, University of Camerino, Camerino, Italy.
Ronconi G; Clinica dei Pazienti del Territorio, Fondazione Policlinico Gemelli, Rome, Italy.
Enrica Gallenga C; Department of Biomedical Sciences and Specialist Surgery, Section of Ophthalmology, University of Ferrara, Ferrara, Italy.
Tetè G; Specialization School in Oral Surgery, Vita-Salute San Raffaele University, 20132 Milan, Italy.
Kritas SK; Department of Microbiology and Infectious Diseases, School of Veterinary Medicine, Aristotle University of Thessaloniki, Macedonia, Greece.
Conti P; Postgraduate Medical School, University of Chieti, Chieti, Italy.
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Źródło :
Medical hypotheses [Med Hypotheses] 2020 Oct; Vol. 143, pp. 109856. Date of Electronic Publication: 2020 May 19.
Typ publikacji :
Letter
MeSH Terms :
Coronavirus Infections/*drug therapy
Cromolyn Sodium/*administration & dosage
Ethanolamines/*administration & dosage
Inflammation/*drug therapy
Lung/*drug effects
Mast Cells/*drug effects
Palmitic Acids/*administration & dosage
Pneumonia, Viral/*drug therapy
Animals ; Antiviral Agents/administration & dosage ; Drug Therapy, Combination ; Humans ; Mice ; Models, Theoretical ; Pandemics ; Respiratory Tract Infections/drug therapy
SCR Disease Name :
COVID-19
Opinia redakcyjna
Tytuł :
The Potential Benefits of Palmitoylethanolamide in Palliation: A Qualitative Systematic Review.
Autorzy :
Davis MP; 1 Geisinger Health System, Danville, PA, USA.
Behm B; 1 Geisinger Health System, Danville, PA, USA.
Mehta Z; 1 Geisinger Health System, Danville, PA, USA.
Fernandez C; 1 Geisinger Health System, Danville, PA, USA.
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Źródło :
The American journal of hospice & palliative care [Am J Hosp Palliat Care] 2019 Dec; Vol. 36 (12), pp. 1134-1154. Date of Electronic Publication: 2019 May 21.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Ethanolamines/*therapeutic use
Palmitic Acids/*therapeutic use
Animals ; Ethanolamines/pharmacology ; Humans ; Mental Disorders/drug therapy ; Neurodegenerative Diseases/drug therapy ; Pain/drug therapy ; Palmitic Acids/pharmacology ; Reperfusion Injury/drug therapy ; Stroke/drug therapy
Czasopismo naukowe
Tytuł :
Effect of dietary supplementation with ultramicronized palmitoylethanolamide in maintaining remission in cats with nonflea hypersensitivity dermatitis: a double-blind, multicentre, randomized, placebo-controlled study.
Autorzy :
Noli C; Servizi Dermatologici Veterinari, Strada Bedale della Ressia 2, 12016, Peveragno, CN, Italy.
Della Valle MF; Science Information and Documentation Centre, Innovet Italia Srl, Via Egadi 7, 20144, Milano, Italy.
Miolo A; Science Information and Documentation Centre, Innovet Italia Srl, Via Egadi 7, 20144, Milano, Italy.
Medori C; Science Information and Documentation Centre, Innovet Italia Srl, Via Egadi 7, 20144, Milano, Italy.
Schievano C; Innovative Statistical Research SRL, Prato della Valle 24, 35123, Padova, Italy.
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Corporate Authors :
Skinalia Clinical Research Group
Źródło :
Veterinary dermatology [Vet Dermatol] 2019 Oct; Vol. 30 (5), pp. 387-e117. Date of Electronic Publication: 2019 Jun 24.
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial, Veterinary
MeSH Terms :
Dietary Supplements*
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Cat Diseases/*prevention & control
Dermatitis, Allergic Contact/*veterinary
Ethanolamines/*pharmacology
Palmitic Acids/*pharmacology
Animals ; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage ; Cats ; Dermatitis, Allergic Contact/prevention & control ; Ethanolamines/administration & dosage ; Palmitic Acids/administration & dosage
Czasopismo naukowe
Tytuł :
Therapeutic Efficacy of Palmitoylethanolamide and Its New Formulations in Synergy with Different Antioxidant Molecules Present in Diets.
Autorzy :
Peritore AF; Department of Chemical Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.
Siracusa R; Department of Chemical Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.
Crupi R; Department of Chemical Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.
Cuzzocrea S; Department of Chemical Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy. .; Department of Pharmacological and Physiological Sciences, Saint Louis University School of Medicine, St. Louis, MO 63104, USA. .
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Źródło :
Nutrients [Nutrients] 2019 Sep 11; Vol. 11 (9). Date of Electronic Publication: 2019 Sep 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Diet, Healthy*
Dietary Supplements*/adverse effects
Anti-Inflammatory Agents/*therapeutic use
Antioxidants/*therapeutic use
Ethanolamines/*therapeutic use
Inflammation/*prevention & control
Palmitic Acids/*therapeutic use
Animals ; Anti-Inflammatory Agents/adverse effects ; Antioxidants/adverse effects ; Drug Synergism ; Ethanolamines/adverse effects ; Ethanolamines/metabolism ; Humans ; Inflammation/metabolism ; Inflammation Mediators/metabolism ; Palmitic Acids/adverse effects ; Palmitic Acids/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Lipid peroxidation inhibition study: A promising case of 1,3-di([1,1'-biphenyl]-3-yl)urea.
Autorzy :
Lazarević J; Department of Chemistry, Faculty of Medicine, University of Niš, Bulevar Dr Zorana Đinđića 81, 18000, Nis, Serbia. Electronic address: .
Šmelcerović A; Department of Chemistry, Faculty of Medicine, University of Niš, Bulevar Dr Zorana Đinđića 81, 18000, Nis, Serbia.
Zvezdanović J; Faculty of Technology, University of Niš, Bulevar oslobođenja 124, 16000, Leskovac, Serbia.
Yancheva D; Institute of Organic Chemistry and Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., Build. 9, 1113, Sofia, Bulgaria.
Casati S; Dipartimento di Scienze Biomediche e Cliniche 'Luigi Sacco', Università degli Studi diMilano, Via G.B. Grassi 74, 20157, Milano, Italy.
Ottria R; Dipartimento di Scienze Biomediche e Cliniche 'Luigi Sacco', Università degli Studi diMilano, Via G.B. Grassi 74, 20157, Milano, Italy.
Ciuffreda P; Dipartimento di Scienze Biomediche e Cliniche 'Luigi Sacco', Università degli Studi diMilano, Via G.B. Grassi 74, 20157, Milano, Italy. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2020 Aug 01; Vol. 326, pp. 109137. Date of Electronic Publication: 2020 May 19.
Typ publikacji :
Journal Article
MeSH Terms :
Biphenyl Compounds/*chemistry
Lipid Peroxidation/*drug effects
Urea/*chemistry
Anilides/chemistry ; Antioxidants/chemistry ; Benzamides/chemistry ; Fatty Acids/chemistry ; Free Radical Scavengers/chemistry ; Free Radicals/chemistry ; Hydrogen/chemistry ; Palmitic Acids/chemistry ; Solvents/chemistry
Czasopismo naukowe
Tytuł :
Increased Anandamide and Decreased Pain and Depression after Exercise in Fibromyalgia.
Autorzy :
Stensson N; Pain and Rehabilitation Centre, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, SWEDEN.
Gerdle B; Pain and Rehabilitation Centre, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, SWEDEN.
Ernberg M; Department of Dental Medicine, Karolinska Institutet, and Scandinavian Centre for Orofacial Neurosciences (SCON), Huddinge, SWEDEN.
Mannerkorpi K; Department of Neuroscience and Physiology, Section of Health and Rehabilitation, Physiotherapy, Sahlgrenska Academy, University of Gothenburg, Göteborg, SWEDEN.; University of Gothenburg Centre for Person Centred Care (GPCC), Sahlgrenska Academy, Göteborg, SWEDEN.
Kosek E; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, SWEDEN.
Ghafouri B; Pain and Rehabilitation Centre, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, SWEDEN.
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Źródło :
Medicine and science in sports and exercise [Med Sci Sports Exerc] 2020 Jul; Vol. 52 (7), pp. 1617-1628.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Pain Management*
Resistance Training*
Arachidonic Acids/*blood
Depression/*therapy
Endocannabinoids/*blood
Exercise Therapy/*methods
Fibromyalgia/*blood
Fibromyalgia/*therapy
Polyunsaturated Alkamides/*blood
Anxiety/therapy ; Ethanolamines/blood ; Fatigue/therapy ; Female ; Fibromyalgia/psychology ; Glycerides/blood ; Humans ; Oleic Acids/blood ; Palmitic Acids/blood ; Stearic Acids/blood
Czasopismo naukowe
Tytuł :
Enzymatic preparation of structured triacylglycerols with arachidonic and palmitic acids at the sn-2 position for infant formula use.
Autorzy :
Wang X; National Engineering Research Center for Functional Food, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, PR China; Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology & Business University (BTBU), 11 Fucheng Road, Beijing 100048, China.
Zou S; National Engineering Research Center for Functional Food, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, PR China.
Miu Z; National Engineering Research Center for Functional Food, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, PR China.
Jin Q; National Engineering Research Center for Functional Food, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, PR China.
Wang X; National Engineering Research Center for Functional Food, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, PR China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2019 Jun 15; Vol. 283, pp. 331-337. Date of Electronic Publication: 2019 Jan 17.
Typ publikacji :
Journal Article
MeSH Terms :
Arachidonic Acid/*metabolism
Infant Formula/*analysis
Palmitic Acids/*metabolism
Triglycerides/*chemistry
Arachidonic Acid/chemistry ; Fatty Acids, Unsaturated/chemistry ; Fatty Acids, Unsaturated/metabolism ; Humans ; Infant ; Lipase/metabolism ; Oleic Acid/chemistry ; Oleic Acid/metabolism ; Palmitic Acids/chemistry ; Triglycerides/metabolism
Czasopismo naukowe
Tytuł :
Metabotropic Glutamate Receptor 5 and 8 Modulate the Ameliorative Effect of Ultramicronized Palmitoylethanolamide on Cognitive Decline Associated with Neuropathic Pain.
Autorzy :
Boccella S; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138 Naples, Italy. .
Marabese I; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138 Naples, Italy. .
Iannotta M; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138 Naples, Italy. .
Belardo C; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138 Naples, Italy. .
Neugebauer V; Department of Pharmacology and Neuroscience, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430-6592, USA. .; Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, TX 79430-6592, USA. .; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430-6592, USA. .
Mazzitelli M; Department of Pharmacology and Neuroscience, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430-6592, USA. .
Pieretti G; Department of Plastic Surgery, University of Campania 'L. Vanvitelli', 80138 Naples, Italy. .
Maione S; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138 Naples, Italy. .
Palazzo E; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138 Naples, Italy. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Apr 09; Vol. 20 (7). Date of Electronic Publication: 2019 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Ethanolamines/*administration & dosage
Neuralgia/*drug therapy
Palmitic Acids/*administration & dosage
Peripheral Nerve Injuries/*drug therapy
Receptor, Metabotropic Glutamate 5/*metabolism
Receptors, Metabotropic Glutamate/*metabolism
Animals ; Dentate Gyrus/drug effects ; Dentate Gyrus/metabolism ; Disease Models, Animal ; Ethanolamines/pharmacology ; Excitatory Postsynaptic Potentials/drug effects ; Humans ; Long-Term Potentiation/drug effects ; Male ; Memory/drug effects ; Mice ; Neuralgia/etiology ; Neuralgia/metabolism ; Olfactory Cortex/drug effects ; Olfactory Cortex/metabolism ; Palmitic Acids/pharmacology ; Peripheral Nerve Injuries/complications ; Peripheral Nerve Injuries/metabolism ; Pyridines/administration & dosage ; Pyridines/pharmacology
Czasopismo naukowe
Tytuł :
N -Palmitoylethanolamide Exerts Antidepressant-Like Effects in Rats: Involvement of PPAR α Pathway in the Hippocampus.
Autorzy :
Li M; Departments of Functional Science (M.L., W.B., Z.-e.J., R.P., H.Y.) and Pharmacology (D.W.), College of Medicine, Yanbian University, Yanji, Jilin, P. R. China.
Wang D; Departments of Functional Science (M.L., W.B., Z.-e.J., R.P., H.Y.) and Pharmacology (D.W.), College of Medicine, Yanbian University, Yanji, Jilin, P. R. China.
Bi W; Departments of Functional Science (M.L., W.B., Z.-e.J., R.P., H.Y.) and Pharmacology (D.W.), College of Medicine, Yanbian University, Yanji, Jilin, P. R. China.
Jiang ZE; Departments of Functional Science (M.L., W.B., Z.-e.J., R.P., H.Y.) and Pharmacology (D.W.), College of Medicine, Yanbian University, Yanji, Jilin, P. R. China.
Piao R; Departments of Functional Science (M.L., W.B., Z.-e.J., R.P., H.Y.) and Pharmacology (D.W.), College of Medicine, Yanbian University, Yanji, Jilin, P. R. China.
Yu H; Departments of Functional Science (M.L., W.B., Z.-e.J., R.P., H.Y.) and Pharmacology (D.W.), College of Medicine, Yanbian University, Yanji, Jilin, P. R. China .
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Źródło :
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2019 Apr; Vol. 369 (1), pp. 163-172. Date of Electronic Publication: 2019 Jan 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antidepressive Agents/*pharmacology
Ethanolamines/*pharmacology
Hippocampus/*drug effects
Hippocampus/*metabolism
PPAR alpha/*metabolism
Palmitic Acids/*pharmacology
Adrenocorticotropic Hormone/blood ; Animals ; Antidepressive Agents/therapeutic use ; Behavior, Animal/drug effects ; Body Weight/drug effects ; Brain-Derived Neurotrophic Factor/metabolism ; Corticosterone/blood ; Ethanolamines/therapeutic use ; Gene Expression Regulation/drug effects ; Glial Cell Line-Derived Neurotrophic Factor/metabolism ; Glutathione/metabolism ; Hippocampus/pathology ; Male ; Malondialdehyde/metabolism ; Organ Size/drug effects ; Palmitic Acids/therapeutic use ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats ; Rats, Sprague-Dawley ; Stress, Psychological/blood ; Stress, Psychological/drug therapy ; Stress, Psychological/metabolism ; Stress, Psychological/pathology ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Hexadecenoic Fatty Acid Positional Isomers and De Novo PUFA Synthesis in Colon Cancer Cells.
Autorzy :
Scanferlato R; Consiglio Nazionale delle Ricerche, ISOF, Area della Ricerca, 40129 Bologna, Italy. .
Bortolotti M; Department of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy. .
Sansone A; Consiglio Nazionale delle Ricerche, ISOF, Area della Ricerca, 40129 Bologna, Italy. .
Chatgilialoglu C; Consiglio Nazionale delle Ricerche, ISOF, Area della Ricerca, 40129 Bologna, Italy. .
Polito L; Department of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy. .
De Spirito M; Istituto di Fisica, Fondazione Policlinico Universitario A.Gemelli IRCSS, 00168 Roma, Italy. .; Istituto di Fisica, Università Cattolica del Sacro Cuore, 00168 Roma, Italy. .
Maulucci G; Istituto di Fisica, Fondazione Policlinico Universitario A.Gemelli IRCSS, 00168 Roma, Italy. .; Istituto di Fisica, Università Cattolica del Sacro Cuore, 00168 Roma, Italy. .
Bolognesi A; Department of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy. .
Ferreri C; Consiglio Nazionale delle Ricerche, ISOF, Area della Ricerca, 40129 Bologna, Italy. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Feb 15; Vol. 20 (4). Date of Electronic Publication: 2019 Feb 15.
Typ publikacji :
Journal Article
MeSH Terms :
Colonic Neoplasms/*metabolism
Fatty Acids, Omega-3/*metabolism
Palmitic Acids/*metabolism
Phospholipids/*chemistry
Caco-2 Cells ; Cell Membrane/chemistry ; Cell Membrane/metabolism ; Cholesterol Esters/biosynthesis ; Cholesterol Esters/chemistry ; Cholesterol Esters/metabolism ; Colonic Neoplasms/chemistry ; Colonic Neoplasms/pathology ; Fatty Acids, Monounsaturated/chemistry ; Fatty Acids, Monounsaturated/pharmacology ; Fatty Acids, Omega-3/biosynthesis ; Humans ; Linoleic Acids/chemistry ; Linoleic Acids/metabolism ; Linoleic Acids/pharmacology ; Linoleoyl-CoA Desaturase/chemistry ; Microscopy, Fluorescence ; Palmitic Acid/chemistry ; Palmitic Acid/metabolism ; Palmitic Acids/chemistry ; Palmitic Acids/pharmacology ; Phospholipids/biosynthesis
Czasopismo naukowe
Tytuł :
N-palmitoylethanolamide Prevents Parkinsonian Phenotypes in Aged Mice.
Autorzy :
Crupi R; Department of Chemical, Biological, Pharmacological and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166, Messina, Italy.
Impellizzeri D; Department of Chemical, Biological, Pharmacological and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166, Messina, Italy.
Cordaro M; Department of Chemical, Biological, Pharmacological and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166, Messina, Italy.
Siracusa R; Department of Chemical, Biological, Pharmacological and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166, Messina, Italy.
Casili G; Department of Chemical, Biological, Pharmacological and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166, Messina, Italy.
Evangelista M; Institute of Anaesthesiology and Reanimation, Catholic University of the Sacred Heart, Rome, Italy.
Cuzzocrea S; Department of Chemical, Biological, Pharmacological and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166, Messina, Italy. .; Department of Pharmacological and Physiological Science, Saint Louis University, Saint Louis, MO, USA. .
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Źródło :
Molecular neurobiology [Mol Neurobiol] 2018 Nov; Vol. 55 (11), pp. 8455-8472. Date of Electronic Publication: 2018 Mar 19.
Typ publikacji :
Journal Article
MeSH Terms :
Aging/*pathology
Ethanolamines/*therapeutic use
Palmitic Acids/*therapeutic use
Parkinson Disease/*drug therapy
Parkinson Disease/*prevention & control
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine ; Animals ; Behavior, Animal/drug effects ; Calcium-Binding Proteins/metabolism ; Cell Membrane/metabolism ; Cell Proliferation/drug effects ; Dentate Gyrus/drug effects ; Dentate Gyrus/metabolism ; Dentate Gyrus/pathology ; Dopamine Plasma Membrane Transport Proteins/metabolism ; Ethanolamines/administration & dosage ; Ethanolamines/pharmacology ; Glial Fibrillary Acidic Protein/metabolism ; Interleukin-1beta/metabolism ; Male ; Mice ; Microfilament Proteins/metabolism ; Palmitic Acids/administration & dosage ; Palmitic Acids/pharmacology ; Parkinson Disease/pathology ; Phenotype ; Protein Aggregates ; Substantia Nigra/drug effects ; Substantia Nigra/metabolism ; Substantia Nigra/pathology ; Tubulin/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Tyrosine 3-Monooxygenase/metabolism ; Up-Regulation/drug effects ; alpha-Synuclein/metabolism
Czasopismo naukowe
Tytuł :
Redox sensitive lipid-camptothecin conjugate encapsulated solid lipid nanoparticles for oral delivery.
Autorzy :
Du Y; School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China.
Ling L; School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China.
Ismail M; School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China.
He W; School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China.
Xia Q; School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China.
Zhou W; School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China.
Yao C; School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China.
Li X; School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China. Electronic address: .
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Źródło :
International journal of pharmaceutics [Int J Pharm] 2018 Oct 05; Vol. 549 (1-2), pp. 352-362. Date of Electronic Publication: 2018 Aug 09.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Carriers*
Nanoparticles*
Camptothecin/*administration & dosage
Lipids/*chemistry
Palmitic Acids/*administration & dosage
Prodrugs/*administration & dosage
Topoisomerase I Inhibitors/*administration & dosage
Administration, Oral ; Animals ; Biological Availability ; Caco-2 Cells ; Camptothecin/chemical synthesis ; Camptothecin/pharmacokinetics ; Camptothecin/toxicity ; Drug Compounding ; Drug Stability ; Female ; HT29 Cells ; Hep G2 Cells ; Humans ; Intestinal Absorption ; MCF-7 Cells ; Mice, Inbred BALB C ; Nanotechnology ; Neoplasms/drug therapy ; Neoplasms/pathology ; Oxidation-Reduction ; Palmitic Acids/chemical synthesis ; Palmitic Acids/pharmacokinetics ; Palmitic Acids/toxicity ; Prodrugs/chemical synthesis ; Prodrugs/pharmacokinetics ; Prodrugs/toxicity ; Technology, Pharmaceutical/methods ; Topoisomerase I Inhibitors/chemical synthesis ; Topoisomerase I Inhibitors/pharmacokinetics ; Topoisomerase I Inhibitors/toxicity
Czasopismo naukowe
Tytuł :
An Optimized Solid-Phase Microextraction and Gas Chromatography-Mass Spectrometry Assay for the Determination of Ethyl Palmitate in Hair.
Autorzy :
Bastiani MF; Laboratory of Analytical Toxicology, Feevale University, Novo Hamburgo, Brazil.; National Institute of Forensic Science and Technology (INCT Forense), Porto Alegre, Brazil.; Graduate Program on Toxicology and Analytical Toxicology, Universidade Feevale, Novo Hamburgo, RS, Brazil.
Lizot LLF; Laboratory of Analytical Toxicology, Feevale University, Novo Hamburgo, Brazil.; National Institute of Forensic Science and Technology (INCT Forense), Porto Alegre, Brazil.; Graduate Program on Toxicology and Analytical Toxicology, Universidade Feevale, Novo Hamburgo, RS, Brazil.
Da Silva ACC; Laboratory of Analytical Toxicology, Feevale University, Novo Hamburgo, Brazil.; Graduate Program on Toxicology and Analytical Toxicology, Universidade Feevale, Novo Hamburgo, RS, Brazil.
Hahn RZ; Laboratory of Analytical Toxicology, Feevale University, Novo Hamburgo, Brazil.
Dries SS; Graduate Program on Toxicology and Analytical Toxicology, Universidade Feevale, Novo Hamburgo, RS, Brazil.
Perassolo MS; Graduate Program on Toxicology and Analytical Toxicology, Universidade Feevale, Novo Hamburgo, RS, Brazil.
Antunes MV; Laboratory of Analytical Toxicology, Feevale University, Novo Hamburgo, Brazil.; Graduate Program on Toxicology and Analytical Toxicology, Universidade Feevale, Novo Hamburgo, RS, Brazil.
Linden R; Laboratory of Analytical Toxicology, Feevale University, Novo Hamburgo, Brazil.; National Institute of Forensic Science and Technology (INCT Forense), Porto Alegre, Brazil.; Graduate Program on Toxicology and Analytical Toxicology, Universidade Feevale, Novo Hamburgo, RS, Brazil.
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Źródło :
Journal of analytical toxicology [J Anal Toxicol] 2020 May 18; Vol. 44 (4), pp. 402-409.
Typ publikacji :
Journal Article
MeSH Terms :
Hair/*chemistry
Palmitic Acids/*analysis
Solid Phase Microextraction/*methods
Esters ; Fatty Acids ; Gas Chromatography-Mass Spectrometry ; Humans ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
Tolerability of Palmitoylethanolamide in a Pediatric Population Suffering from Migraine: A Pilot Study.
Autorzy :
Papetti L; Headache Center, Department of Neuroscience, Bambino Gesù Children Hospital in Rome, Rome, Italy.
Sforza G; Child Neurology Unit, Systems Medicine Department, Tor Vergata University Hospital of Rome, Rome, Italy.
Tullo G; Department of Neurosciences, Mental Health, and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sant'Andrea Hospital, Sapienza University, Rome, Italy.
Alaimo di Loro P; Department of Statistical Sciences, Sapienza University of Rome, Rome, Italy.
Moavero R; Child Neurology Unit, Systems Medicine Department, Tor Vergata University Hospital of Rome, Rome, Italy.
Ursitti F; Headache Center, Department of Neuroscience, Bambino Gesù Children Hospital in Rome, Rome, Italy.
Ferilli MAN; Headache Center, Department of Neuroscience, Bambino Gesù Children Hospital in Rome, Rome, Italy.
Tarantino S; Headache Center, Department of Neuroscience, Bambino Gesù Children Hospital in Rome, Rome, Italy.
Vigevano F; Headache Center, Department of Neuroscience, Bambino Gesù Children Hospital in Rome, Rome, Italy.
Valeriani M; Headache Center, Department of Neuroscience, Bambino Gesù Children Hospital in Rome, Rome, Italy.; Center for Sensory-Motor Interaction, Aalborg University, Denmark Neurology Unit, Aalborg, Denmark.
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Źródło :
Pain research & management [Pain Res Manag] 2020 Apr 24; Vol. 2020, pp. 3938640. Date of Electronic Publication: 2020 Apr 24 (Print Publication: 2020).
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Analgesics/*therapeutic use
Ethanolamines/*therapeutic use
Migraine Disorders/*prevention & control
Palmitic Acids/*therapeutic use
Child ; Female ; Humans ; Male ; Pilot Projects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Satiety Factors Oleoylethanolamide, Stearoylethanolamide, and Palmitoylethanolamide in Mother's Milk Are Strongly Associated with Infant Weight at Four Months of Age-Data from the Odense Child Cohort.
Autorzy :
Bruun S; Strategic Business Unit Pediatric, Arla Foods Ingredients Group P/S, DK-8260 Viby J, Denmark. .; Hans Christian Andersen Children's Hospital, Odense University Hospital, DK-5000 Odense C, Denmark. .; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, DK-5000 Odense C, Denmark. .
Gouveia-Figueira S; Clinical Chemistry, County Council of Västerbotten, SE-901 85 Umeå, Sweden. .
Domellöf M; Department of Clinical Sciences, Pediatrics, Umeå University, SE-901 87 Umeå, Sweden. .
Husby S; Hans Christian Andersen Children's Hospital, Odense University Hospital, DK-5000 Odense C, Denmark. .; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, DK-5000 Odense C, Denmark. .
Neergaard Jacobsen L; Strategic Business Unit Pediatric, Arla Foods Ingredients Group P/S, DK-8260 Viby J, Denmark. .
Michaelsen KF; Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, DK-1958 Frederiksberg C, Denmark. .
Fowler CJ; Department of Pharmacology and Clinical Neuroscience, Umeå University, SE-901 87 Umeå, Sweden. .
Zachariassen G; Hans Christian Andersen Children's Hospital, Odense University Hospital, DK-5000 Odense C, Denmark. .; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, DK-5000 Odense C, Denmark. .
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Źródło :
Nutrients [Nutrients] 2018 Nov 13; Vol. 10 (11). Date of Electronic Publication: 2018 Nov 13.
Typ publikacji :
Journal Article
MeSH Terms :
Body Weight*
Endocannabinoids/*metabolism
Ethanolamines/*metabolism
Milk, Human/*chemistry
Oleic Acids/*metabolism
Palmitic Acids/*metabolism
Stearic Acids/*metabolism
Adult ; Aging ; Breast Feeding ; Cohort Studies ; Denmark ; Endocannabinoids/chemistry ; Ethanolamines/chemistry ; Female ; Humans ; Infant ; Milk, Human/metabolism ; Oleic Acids/chemistry ; Palmitic Acids/chemistry ; Stearic Acids/chemistry
Czasopismo naukowe
Tytuł :
Palmitoylethanolamide counteracts autistic-like behaviours in BTBR T+tf/J mice: Contribution of central and peripheral mechanisms.
Autorzy :
Cristiano C; Department of Pharmacy, University of Naples 'Federico II', 80131 Naples, Italy.
Pirozzi C; Department of Pharmacy, University of Naples 'Federico II', 80131 Naples, Italy.
Coretti L; Task Force on Microbiome Studies, University of Naples 'Federico II', 80131 Naples, Italy; Institute for Experimental Endocrinology and Oncology, IEOS, Consiglio Nazionale delle Ricerche CNR, Via S. Pansini, 5, 80131, Naples, Italy.
Cavaliere G; Department of Biology, University of Naples 'Federico II', 80131 Naples, Italy.
Lama A; Department of Pharmacy, University of Naples 'Federico II', 80131 Naples, Italy; Task Force on Microbiome Studies, University of Naples 'Federico II', 80131 Naples, Italy.
Russo R; Department of Pharmacy, University of Naples 'Federico II', 80131 Naples, Italy.
Lembo F; Department of Pharmacy, University of Naples 'Federico II', 80131 Naples, Italy; Task Force on Microbiome Studies, University of Naples 'Federico II', 80131 Naples, Italy.
Mollica MP; Department of Biology, University of Naples 'Federico II', 80131 Naples, Italy.
Meli R; Department of Pharmacy, University of Naples 'Federico II', 80131 Naples, Italy.
Calignano A; Department of Pharmacy, University of Naples 'Federico II', 80131 Naples, Italy.
Mattace Raso G; Department of Pharmacy, University of Naples 'Federico II', 80131 Naples, Italy; Task Force on Microbiome Studies, University of Naples 'Federico II', 80131 Naples, Italy. Electronic address: .
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Źródło :
Brain, behavior, and immunity [Brain Behav Immun] 2018 Nov; Vol. 74, pp. 166-175. Date of Electronic Publication: 2018 Sep 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autism Spectrum Disorder/*drug therapy
Autism Spectrum Disorder/*metabolism
Ethanolamines/*pharmacology
Palmitic Acids/*pharmacology
Animals ; Autistic Disorder/drug therapy ; Autistic Disorder/metabolism ; Brain/metabolism ; Brain-Derived Neurotrophic Factor/metabolism ; Colon/metabolism ; Cytokines/metabolism ; Disease Models, Animal ; Ethanolamines/metabolism ; Gastrointestinal Microbiome/drug effects ; Hippocampus/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/drug effects ; PPAR alpha/drug effects ; PPAR alpha/metabolism ; Palmitic Acids/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe

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