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Tytuł:
Intraoperative electrochemotherapy of the posterior resection surface after pancreaticoduodenectomy: Preliminary results of a hybrid approach treatment of pancreatic cancer.
Autorzy:
Čebron Ž; University Medical Centre Ljubljana, Department of Abdominal Surgery, Zaloska 7, SI-1000 Ljubljana, Slovenia; University of Ljubljana, Medical Faculty, Vrazov trg 2, 1000 Ljubljana, Slovenia.
Djokić M; University Medical Centre Ljubljana, Department of Abdominal Surgery, Zaloska 7, SI-1000 Ljubljana, Slovenia; University of Ljubljana, Medical Faculty, Vrazov trg 2, 1000 Ljubljana, Slovenia.
Petrič M; University Medical Centre Ljubljana, Department of Abdominal Surgery, Zaloska 7, SI-1000 Ljubljana, Slovenia; University of Ljubljana, Medical Faculty, Vrazov trg 2, 1000 Ljubljana, Slovenia.
Čemažar M; Institute of Oncology Ljubljana, Department of Experimental Oncology, Zaloska 2, SI-1000 Ljubljana, Slovenia; University of Primorska, Faculty of Health Sciences, Polje 42, SI-6310 Izola, Slovenia.
Bošnjak M; Institute of Oncology Ljubljana, Department of Experimental Oncology, Zaloska 2, SI-1000 Ljubljana, Slovenia.
Serša G; Institute of Oncology Ljubljana, Department of Experimental Oncology, Zaloska 2, SI-1000 Ljubljana, Slovenia; University of Ljubljana, Faculty of Health Sciences, Zdravstvena pot 5, SI-1000 Ljubljana, Slovenia. Electronic address: .
Trotovšek B; University Medical Centre Ljubljana, Department of Abdominal Surgery, Zaloska 7, SI-1000 Ljubljana, Slovenia; University of Ljubljana, Medical Faculty, Vrazov trg 2, 1000 Ljubljana, Slovenia. Electronic address: .
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Źródło:
Bioelectrochemistry (Amsterdam, Netherlands) [Bioelectrochemistry] 2024 Feb; Vol. 155, pp. 108576. Date of Electronic Publication: 2023 Sep 22.
Typ publikacji:
Journal Article
MeSH Terms:
Electrochemotherapy*/methods
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/surgery
Adenocarcinoma*
Humans ; Pancreaticoduodenectomy/adverse effects ; Pancreaticoduodenectomy/methods ; Prospective Studies ; Pilot Projects ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
No changes in clinical presentation, treatment strategies and survival of pancreatic cancer cases during the SARS-COV-2 outbreak: A retrospective multicenter cohort study on real-world data.
Autorzy:
Kempf E; Laboratoire d'Informatique Médicale et d'Ingénierie des Connaissances pour la e-Santé (LIMICS), Université Sorbonne Paris Nord, Sorbonne Université, Inserm, Paris, France.; Department of Medical Oncology, Assistance Publique - Hôpitaux de Paris, Henri Mondor and Albert Chenevier Teaching Hospital, Université Paris Est Créteil, Créteil, France.
Priou S; IT Department, Assistance Publique - Hôpitaux de Paris, Innovation and Data, Paris, France.; Université Paris-Saclay, CentraleSupélec, Laboratoire Génie Industriel, Gif-sur-Yvette, France.
Lamé G; Université Paris-Saclay, CentraleSupélec, Laboratoire Génie Industriel, Gif-sur-Yvette, France.
Laurent A; Department of Digestive Surgery, Assistance Publique - Hôpitaux de Paris, Henri Mondor and Albert Chenevier Teaching Hospital, Université Paris Est Créteil, Créteil, France.
Guével E; IT Department, Assistance Publique - Hôpitaux de Paris, Innovation and Data, Paris, France.
Tzedakis S; Department of Digestive Surgery, Assistance Publique - Hôpitaux de Paris, Cochin Teaching Hospital, Université Paris City, Paris, France.
Bey R; IT Department, Assistance Publique - Hôpitaux de Paris, Innovation and Data, Paris, France.
Fuks D; Department of Digestive Surgery, Assistance Publique - Hôpitaux de Paris, Cochin Teaching Hospital, Université Paris City, Paris, France.
Chatellier G; Department of Medical Informatics, Assistance Publique - Hôpitaux de Paris, Centre-Université de Paris (APHP-CUP), Université de Paris, Paris, France.
Tannier X; Laboratoire d'Informatique Médicale et d'Ingénierie des Connaissances pour la e-Santé (LIMICS), Université Sorbonne Paris Nord, Sorbonne Université, Inserm, Paris, France.
Galula G; Department of Medical Oncology, Assistance Publique - Hôpitaux de Paris, Tenon Teaching Hospital, Université Sorbonne, Paris, France.
Flicoteaux R; Department of Medical Information, Assistance Publique - Hôpitaux de Paris, Paris, France.
Daniel C; IT Department, Assistance Publique - Hôpitaux de Paris, Innovation and Data, Paris, France.
Tournigand C; Department of Medical Oncology, Assistance Publique - Hôpitaux de Paris, Henri Mondor and Albert Chenevier Teaching Hospital, Université Paris Est Créteil, Créteil, France.
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Corporate Authors:
Assistance Publique - Hôpitaux de Paris (AP-HP) Cancer Group, a Cancer Research Application on Big Data (CRAB) Initiative
Źródło:
International journal of cancer [Int J Cancer] 2023 Dec 15; Vol. 153 (12), pp. 1988-1996. Date of Electronic Publication: 2023 Aug 04.
Typ publikacji:
Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*/epidemiology
Pancreatic Neoplasms*/epidemiology
Pancreatic Neoplasms*/therapy
Humans ; SARS-CoV-2 ; Cohort Studies ; Communicable Disease Control ; Retrospective Studies ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Transcriptomics and molecular docking reveal the potential mechanism of lycorine against pancreatic cancer.
Autorzy:
Zhou X; The Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Ministry of Education, Shihezi University Medical College, Shihezi 832002, China; NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, Shihezi 832002, China; Department of Physiology, Shihezi University Medical College, Shihezi 832002, China.
Guo Z; The Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Ministry of Education, Shihezi University Medical College, Shihezi 832002, China; NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, Shihezi 832002, China; Department of Physiology, Shihezi University Medical College, Shihezi 832002, China.
Liu S; The Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Ministry of Education, Shihezi University Medical College, Shihezi 832002, China; NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, Shihezi 832002, China; Department of Physiology, Shihezi University Medical College, Shihezi 832002, China.
Chen Z; The Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Ministry of Education, Shihezi University Medical College, Shihezi 832002, China; NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, Shihezi 832002, China; Department of Pathophysiology, Shihezi University Medical College, Shihezi 832002, China.
Wang Y; The Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Ministry of Education, Shihezi University Medical College, Shihezi 832002, China; NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, Shihezi 832002, China.
Yang R; The Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Ministry of Education, Shihezi University Medical College, Shihezi 832002, China; NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, Shihezi 832002, China; Department of Physiology, Shihezi University Medical College, Shihezi 832002, China. Electronic address: .
Li X; The Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Ministry of Education, Shihezi University Medical College, Shihezi 832002, China; NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, Shihezi 832002, China; Department of Pathophysiology, Shihezi University Medical College, Shihezi 832002, China. Electronic address: .
Ma K; The Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Ministry of Education, Shihezi University Medical College, Shihezi 832002, China; NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, Shihezi 832002, China; Department of Physiology, Shihezi University Medical College, Shihezi 832002, China. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jan; Vol. 122, pp. 155128. Date of Electronic Publication: 2023 Oct 04.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/pharmacology
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/pathology
Animals ; Mice ; Molecular Docking Simulation ; Cell Line, Tumor ; Transcriptome ; Cell Proliferation ; Apoptosis ; RNA, Small Interfering/pharmacology ; Fatty Acids ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Cancer-associated fibroblasts drive early pancreatic cancer cell invasion via the SOX4/MMP11 signalling axis.
Autorzy:
Ge F; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Zeng C; College of Agriculture & Biotechnology, Zhejiang University, Hangzhou, China; Innovation Institute for Artificial Intelligence in Medicine, Zhejiang University, Hangzhou, China.
Wang J; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Liu X; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Zheng C; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Zhang H; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Yang L; Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Zhejiang Provincial People's Hospital, Hangzhou, China.
Yang B; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Zhu H; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China. Electronic address: .
He Q; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, China.
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Źródło:
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2024 Jan; Vol. 1870 (1), pp. 166852. Date of Electronic Publication: 2023 Aug 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cancer-Associated Fibroblasts*/pathology
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/pathology
Carcinoma, Pancreatic Ductal*/genetics
Humans ; Matrix Metalloproteinase 11 ; Neoplasm Invasiveness/pathology ; SOXC Transcription Factors/genetics ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
A co-carrier for plasmid DNA and curcumin delivery to treat pancreatic cancer via dendritic poly(l-lysine) modified amylose.
Autorzy:
Pang J; DSAPM Lab and PCFM Lab, School of Materials Science and Engineering, Sun Yat-sen University, Guangzhou 510275, China; Medical Intelligence and Innovation Academy, South University of Science and Technology Hospital, Shenzhen 518000, China.
Zhuang B; Department of General Surgery & Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Zhang LM; DSAPM Lab and PCFM Lab, School of Materials Science and Engineering, Sun Yat-sen University, Guangzhou 510275, China. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Dec 31; Vol. 253 (Pt 7), pp. 127467. Date of Electronic Publication: 2023 Oct 19.
Typ publikacji:
Journal Article
MeSH Terms:
Curcumin*/pharmacology
Dendrimers*/chemistry
Antineoplastic Agents*
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Humans ; Amylose/chemistry ; Polylysine/chemistry ; Tumor Necrosis Factor-alpha ; Gene Transfer Techniques ; Plasmids/genetics ; DNA/genetics ; DNA/chemistry ; Polymers/chemistry ; Drug Carriers ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Dysregulation of the circ_0087502/miR-1179/TGFBR2 pathway supports gemcitabine resistance in pancreatic cancer.
Autorzy:
Chen M; Department of hepatobiliary and pancreatic surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.; Department of hepatobiliary and pancreatic surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Liu X; Department of ultrasound, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Lu J; Department of hepatobiliary and pancreatic surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Teng H; Department of hepatobiliary and pancreatic surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Yu C; Department of hepatobiliary and pancreatic surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Liu Y; Department of Cell Biology and Genetics, Fujian Medical University, Fuzhou, China.
Zheng Y; Department of hepatobiliary and pancreatic surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
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Źródło:
Cancer biology & therapy [Cancer Biol Ther] 2023 Dec 31; Vol. 24 (1), pp. 2258566. Date of Electronic Publication: 2023 Oct 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
MicroRNAs*/genetics
MicroRNAs*/metabolism
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Humans ; RNA, Circular/genetics ; Gemcitabine ; Receptor, Transforming Growth Factor-beta Type II/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Pancreatic Cancer: A Review of Current Treatment and Novel Therapies.
Autorzy:
Kolbeinsson HM; Spectrum Health General Surgery Residency, Grand Rapids, Michigan, USA.; Department of Surgery, Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA.
Chandana S; Department of Surgery, Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA.; Cancer and Hematology Centers of Western Michigan, PC, Grand Rapids, Michigan, USA.
Wright GP; Spectrum Health General Surgery Residency, Grand Rapids, Michigan, USA.; Department of Surgery, Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA.; Division of Surgical Oncology, Spectrum Health Medical Group, Grand Rapids, Michigan, USA.
Chung M; Spectrum Health General Surgery Residency, Grand Rapids, Michigan, USA.; Department of Surgery, Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA.; Division of Surgical Oncology, Spectrum Health Medical Group, Grand Rapids, Michigan, USA.
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Źródło:
Journal of investigative surgery : the official journal of the Academy of Surgical Research [J Invest Surg] 2023 Dec 31; Vol. 36 (1), pp. 2129884. Date of Electronic Publication: 2022 Oct 03.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pancreatic Neoplasms*/therapy
Pancreatic Neoplasms*/drug therapy
Antineoplastic Agents*/therapeutic use
Humans ; United States ; Combined Modality Therapy ; Neoadjuvant Therapy ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Timing of start of systemic treatment in patients with asymptomatic metastasized pancreatic cancer (TIMEPAN): a protocol of a multicenter prospective patient preference non-randomized trial.
Autorzy:
Augustinus S; Amsterdam UMC, Department of Surgery, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Amsterdam, The Netherlands.
Broekman T; Cancer Center Amsterdam, Amsterdam, The Netherlands.; Amsterdam UMC, Department of Medical Oncology, University of Amsterdam, Amsterdam, The Netherlands.
Creemers GJ; Department of Medical Oncology, Catherina Hospital, Eindhoven, The Netherlands.
Daamen LA; Division of Imaging & Oncology, University Medical Center Utrecht Cancer Center, Utrecht University, Utrecht, The Netherlands.; Department of Surgery, University Medical Center Utrecht Cancer Center, St Antonius Hospital Nieuwegein, Regional Academic Cancer Center Utrecht, University of Utrecht, Utrecht, The Netherlands.
van Dieren S; Amsterdam UMC, Department of Surgery, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Amsterdam, The Netherlands.
de Groot JB; Department of Medical Oncology, Oncology Center Isala, Zwolle, The Netherlands.
Cirkel GA; Department of Medical Oncology, Regional Academic Cancer Center Utrecht, Meander Medisch Centrum, Amersfoort, The Netherlands.
Homs MYV; Department of Medical Oncology, Erasmus Medical Center, Rotterdam, The Netherlands.
van Laarhoven HWM; Cancer Center Amsterdam, Amsterdam, The Netherlands.; Amsterdam UMC, Department of Medical Oncology, University of Amsterdam, Amsterdam, The Netherlands.
van Leeuwen L; Department of Medical Oncology, Regional Academic Cancer Center Utrecht, Diakonessenhuis, Utrecht, The Netherlands.
Los M; Department of Medical Oncology, Regional Academic Cancer Center Utrecht, St. Antonius Ziekenhuis, Nieuwegein, The Netherlands.
Luelmo SAC; Department of Medical Oncology, Leids Universitair Medisch Centrum, Leiden, The Netherlands.
van Oijen MGH; Cancer Center Amsterdam, Amsterdam, The Netherlands.; Amsterdam UMC, Department of Medical Oncology, University of Amsterdam, Amsterdam, The Netherlands.
Spierings LEAM; Department of Medical Oncology, Alrijne Ziekenhuis, Leiderdorp, The Netherlands.
de Vos-Geelen J; Department of Medical Oncology, GROW, Maastricht UMC, Maastsricht, The Netherlands.
Besselink MG; Amsterdam UMC, Department of Surgery, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Amsterdam, The Netherlands.
Wilmink JW; Cancer Center Amsterdam, Amsterdam, The Netherlands.; Amsterdam UMC, Department of Medical Oncology, University of Amsterdam, Amsterdam, The Netherlands.
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Corporate Authors:
Dutch Pancreatic Cancer Group
Źródło:
Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2023 Dec; Vol. 62 (12), pp. 1973-1978. Date of Electronic Publication: 2023 Nov 25.
Typ publikacji:
Journal Article
MeSH Terms:
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/pathology
Patient Preference*
Humans ; Multicenter Studies as Topic ; Pancreas/pathology ; Prospective Studies ; Clinical Trials as Topic ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
IGF2 is upregulated by its antisense RNA to potentiate pancreatic cancer progression.
Autorzy:
Tian Y; Department of General Surgery, Ningbo Medical Center Lihuili Hospital, The Affiliated Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, 315100, China.
Han W; Department of Emergency, Ningbo Medical Center Lihuili Hospital, The Affiliated Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, 315100, China.
Fu L; Department of General Surgery, Ningbo Medical Center Lihuili Hospital, The Affiliated Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, 315100, China.
Zhang J; Department of General Surgery, Ningbo Medical Center Lihuili Hospital, The Affiliated Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, 315100, China.
Zhou X; Department of General Surgery, Ningbo Medical Center Lihuili Hospital, The Affiliated Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, 315100, China. .
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Źródło:
Functional & integrative genomics [Funct Integr Genomics] 2023 Dec 01; Vol. 23 (4), pp. 348. Date of Electronic Publication: 2023 Dec 01.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/genetics
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/metabolism
Pancreatic Neoplasms*/pathology
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Animals ; Mice ; Cell Line, Tumor ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; RNA, Antisense/genetics ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
CA9 and PRELID2; hypoxia-responsive potential therapeutic targets for pancreatic ductal adenocarcinoma as per bioinformatics analyses.
Autorzy:
Imanishi M; Department of Medical Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, Japan. Electronic address: .
Inoue T; Department of Medical Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, Japan; Department of Pharmacy, Tokushima University Hospital, Japan.
Fukushima K; Department of Pharmacology for Life Sciences, Graduate School of Biomedical Sciences, Tokushima University, Japan. Electronic address: .
Yamashita R; Department of Medical Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, Japan.
Nakayama R; Department of Medical Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, Japan.
Nojima M; Department of Medical Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, Japan.
Kondo K; Department of Medical Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, Japan.
Gomi Y; Department of Medical Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, Japan.
Tsunematsu H; Department of Medical Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, Japan.
Goto K; Department of Medical Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, Japan.
Miyamoto L; Laboratory of Pharmacology and Food Science, Department of Nutrition and Life Science, Faculty of Health and Medical Sciences, Kanagawa Institute of Technology, Japan.
Funamoto M; Department of Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, Japan.
Denda M; Department of Bioorganic Synthetic Chemistry, Graduate School of Biomedical Sciences, Tokushima University, Japan.
Ishizawa K; Department of Pharmacy, Tokushima University Hospital, Japan; Department of Clinical Pharmacology and Therapeutics, Graduate School of Biomedical Sciences, Tokushima University, Japan; Clinical Research Center for Developmental Therapeutics, Tokushima University Hospital, Japan.
Otaka A; Department of Bioorganic Synthetic Chemistry, Graduate School of Biomedical Sciences, Tokushima University, Japan.
Fujino H; Department of Pharmacology for Life Sciences, Graduate School of Biomedical Sciences, Tokushima University, Japan.
Ikeda Y; Department of Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, Japan.
Tsuchiya K; Department of Medical Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, Japan.
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Źródło:
Journal of pharmacological sciences [J Pharmacol Sci] 2023 Dec; Vol. 153 (4), pp. 232-242. Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Pancreatic Ductal*/drug therapy
Carcinoma, Pancreatic Ductal*/genetics
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Humans ; Carbonic Anhydrase IX/genetics ; Carbonic Anhydrase IX/metabolism ; Antigens, Neoplasm/genetics ; Antigens, Neoplasm/metabolism ; Antigens, Neoplasm/therapeutic use ; Hypoxia/metabolism ; RNA, Small Interfering ; Computational Biology ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Organic Selenium induces ferroptosis in pancreatic cancer cells.
Autorzy:
Noè R; Veneto Institute of Molecular Medicine (VIMM), 35129, Padova, Italy; Department of Biology, University of Padova, 35126, Padova, Italy.
Inglese N; Veneto Institute of Molecular Medicine (VIMM), 35129, Padova, Italy; Department of Biology, University of Padova, 35126, Padova, Italy.
Romani P; Department of Molecular Medicine, University of Padova, 35126, Padova, Italy.
Serafini T; Veneto Institute of Molecular Medicine (VIMM), 35129, Padova, Italy.
Paoli C; Veneto Institute of Molecular Medicine (VIMM), 35129, Padova, Italy; Department of Biology, University of Padova, 35126, Padova, Italy.
Calciolari B; Veneto Institute of Molecular Medicine (VIMM), 35129, Padova, Italy; Department of Biology, University of Padova, 35126, Padova, Italy.
Fantuz M; Veneto Institute of Molecular Medicine (VIMM), 35129, Padova, Italy; Department of Biology, University of Padova, 35126, Padova, Italy.
Zamborlin A; NEST-Scuola Normale Superiore, 56127, Pisa, Italy; Center for Nanotechnology Innovation, Istituto Italiano di Tecnologia, 56127, Pisa, Italy.
Surdo NC; Veneto Institute of Molecular Medicine (VIMM), 35129, Padova, Italy; Neuroscience Institute, National Research Council (CNR), 35121, Padova, Italy.
Spada V; Veneto Institute of Molecular Medicine (VIMM), 35129, Padova, Italy.
Spacci M; Veneto Institute of Molecular Medicine (VIMM), 35129, Padova, Italy; Department of Biology, University of Padova, 35126, Padova, Italy.
Volta S; Veneto Institute of Molecular Medicine (VIMM), 35129, Padova, Italy.
Ermini ML; Center for Nanotechnology Innovation, Istituto Italiano di Tecnologia, 56127, Pisa, Italy.
Di Benedetto G; Veneto Institute of Molecular Medicine (VIMM), 35129, Padova, Italy; Neuroscience Institute, National Research Council (CNR), 35121, Padova, Italy.
Frusca V; Center for Nanotechnology Innovation, Istituto Italiano di Tecnologia, 56127, Pisa, Italy; Scuola Superiore Sant'Anna, Piazza Martiri della Libertà 33, 56127, Pisa, Italy.
Santi C; Group of Catalysis and Green Organic Chemistry, Department of Pharmaceutical Sciences, University of Perugia, 06122, Perugia, PG, Italy.
Lefkimmiatis K; Veneto Institute of Molecular Medicine (VIMM), 35129, Padova, Italy; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Dupont S; Department of Molecular Medicine, University of Padova, 35126, Padova, Italy.
Voliani V; Center for Nanotechnology Innovation, Istituto Italiano di Tecnologia, 56127, Pisa, Italy; Department of Pharmacy, School of Medical and Pharmaceutical Sciences, University of Genova, 16148, Genoa, Italy. Electronic address: .
Sancineto L; Group of Catalysis and Green Organic Chemistry, Department of Pharmaceutical Sciences, University of Perugia, 06122, Perugia, PG, Italy. Electronic address: .
Carrer A; Veneto Institute of Molecular Medicine (VIMM), 35129, Padova, Italy; Department of Biology, University of Padova, 35126, Padova, Italy. Electronic address: .
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Źródło:
Redox biology [Redox Biol] 2023 Dec; Vol. 68, pp. 102962. Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article
MeSH Terms:
Ferroptosis*
Selenium*
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/pathology
Humans ; Pancreas ; Lipid Peroxidation ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Health Disparities in Presentation, Treatment, Genomic Testing, and Outcomes of Pancreatic Cancer in Hispanic and Non-Hispanic Patients.
Autorzy:
Halder R; University of Arizona Internal Medicine Residency Program, Tucson, AZ, USA. .; Tecnológico de Monterrey Escuela de Medicina y Ciencias de la Salud, Monterrey, N.L., Mexico. .; University of Arizona Cancer Center, Tucson, AZ, USA. .
Veeravelli S; University of Arizona Internal Medicine Residency Program, Tucson, AZ, USA.; Tecnológico de Monterrey Escuela de Medicina y Ciencias de la Salud, Monterrey, N.L., Mexico.; University of Arizona Cancer Center, Tucson, AZ, USA.
Cheng C; University of Arizona Internal Medicine Residency Program, Tucson, AZ, USA.; Tecnológico de Monterrey Escuela de Medicina y Ciencias de la Salud, Monterrey, N.L., Mexico.; University of Arizona Cancer Center, Tucson, AZ, USA.
Estrada-Mendizabal RJ; University of Arizona Internal Medicine Residency Program, Tucson, AZ, USA.; Tecnológico de Monterrey Escuela de Medicina y Ciencias de la Salud, Monterrey, N.L., Mexico.; University of Arizona Cancer Center, Tucson, AZ, USA.
Recio-Boiles A; University of Arizona Internal Medicine Residency Program, Tucson, AZ, USA.; Tecnológico de Monterrey Escuela de Medicina y Ciencias de la Salud, Monterrey, N.L., Mexico.; University of Arizona Cancer Center, Tucson, AZ, USA.
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Źródło:
Journal of racial and ethnic health disparities [J Racial Ethn Health Disparities] 2023 Dec; Vol. 10 (6), pp. 3131-3139. Date of Electronic Publication: 2023 Apr 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/therapy
Adenocarcinoma*/genetics
Adenocarcinoma*/therapy
Humans ; Middle Aged ; Ethnicity ; Retrospective Studies ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Clinical outcomes and response to chemotherapy in a cohort of pancreatic cancer patients with germline variants of unknown significance (VUS) in BRCA1 and BRCA2 genes.
Autorzy:
Militello AM; Department of Medical Oncology, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20123, Milan, Italy.; Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy.
Orsi G; Department of Medical Oncology, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20123, Milan, Italy.; Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy.
Cavaliere A; Department of Oncology, University of Torino, Candiolo, Italy.; Candiolo Cancer Institute, FPO - IRCCS Candiolo, Candiolo, Italy.
Niger M; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori Di Milano, Milan, Italy.
Avallone A; Biologia Cellulare e Bioterapie, Istituto Nazionale per lo Studio e la Cura dei Tumori ''Fondazione Giovanni Pascale'' - IRCCS, Naples, Italy.
Salvatore L; Unit of Medical Oncology, Comprehensive Cancer Center, Fondazione Policlinico Universitario, Agostino Gemelli IRCCS, Rome, Italy.; Università Cattolica del Sacro Cuore, Rome, Italy.
Tortora G; Unit of Medical Oncology, Comprehensive Cancer Center, Fondazione Policlinico Universitario, Agostino Gemelli IRCCS, Rome, Italy.; Università Cattolica del Sacro Cuore, Rome, Italy.
Rapposelli IG; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) ''Dino Amadori'', Meldola, Italy.
Giordano G; Unit of Medical Oncology and Biomolecular Therapy, Policlinico Riuniti, Foggia, Italy.; Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Noventa S; Department of Medical Oncology, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.
Giommoni E; Medical Oncology Division, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Bozzarelli S; Department of Medical Oncology and Hematology, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Milan, Italy.
Macchini M; Department of Medical Oncology, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20123, Milan, Italy.; Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy.
Peretti U; Department of Medical Oncology, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20123, Milan, Italy.; Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy.
Procaccio L; Medical Oncology 1 Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.
Puccini A; University of Genoa, Ospedale Policlinico San Martino IRCCS, Genoa, Italy.
Cascinu S; Department of Medical Oncology, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20123, Milan, Italy.; Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy.
Montagna C; Department of Radiation Oncology and Genomic Instability and Cancer Genetics, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
Milella M; Section of Oncology, Department of Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy.
Reni M; Department of Medical Oncology, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20123, Milan, Italy. .; Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy. .
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Źródło:
Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2023 Dec; Vol. 92 (6), pp. 501-510. Date of Electronic Publication: 2023 Sep 19.
Typ publikacji:
Journal Article
MeSH Terms:
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/pathology
Humans ; Genes, BRCA2 ; BRCA1 Protein/genetics ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Retrospective Studies ; BRCA2 Protein/genetics ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Single-cell sequencing in pancreatic cancer research: A deeper understanding of heterogeneity and therapy.
Autorzy:
Liu Z; Department of Radiation Oncology, the Fourth Affiliated Hospital of China Medical University, Shenyang, China.
Zhang Y; Department of Radiation Oncology, the Fourth Affiliated Hospital of China Medical University, Shenyang, China.
Wu C; Department of Radiation Oncology, the Fourth Affiliated Hospital of China Medical University, Shenyang, China. Electronic address: .
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Dec; Vol. 168, pp. 115664. Date of Electronic Publication: 2023 Oct 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Carcinoma, Pancreatic Ductal*/drug therapy
Carcinoma, Pancreatic Ductal*/genetics
Humans ; Tumor Microenvironment/genetics ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Highly Reproducible Quantitative Proteomics Analysis of Pancreatic Cancer Cells Reveals Proteome-Level Effects of a Novel Combination Drug Therapy That Induces Cancer Cell Death via Metabolic Remodeling and Activation of the Extrinsic Apoptosis Pathway.
Autorzy:
Rasam S; Department of Biochemistry, University at Buffalo, Buffalo, New York 14260, United States.; New York State Center of Excellence in Bioinformatics and Life Sciences, 701 Ellicott Street, Buffalo, New York 14203, United States.
Lin Q; Department of Pharmaceutical Sciences, University at Buffalo, Buffalo, New York 14260, United States.; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, New York 14203, United States.
Shen S; New York State Center of Excellence in Bioinformatics and Life Sciences, 701 Ellicott Street, Buffalo, New York 14203, United States.
Straubinger RM; New York State Center of Excellence in Bioinformatics and Life Sciences, 701 Ellicott Street, Buffalo, New York 14203, United States.; Department of Pharmaceutical Sciences, University at Buffalo, Buffalo, New York 14260, United States.; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, New York 14203, United States.
Qu J; Department of Biochemistry, University at Buffalo, Buffalo, New York 14260, United States.; New York State Center of Excellence in Bioinformatics and Life Sciences, 701 Ellicott Street, Buffalo, New York 14203, United States.; Department of Pharmaceutical Sciences, University at Buffalo, Buffalo, New York 14260, United States.; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, New York 14203, United States.
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Źródło:
Journal of proteome research [J Proteome Res] 2023 Dec 01; Vol. 22 (12), pp. 3780-3792. Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Proteome*/analysis
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/metabolism
Humans ; Proteomics/methods ; Gemcitabine ; Peptides/analysis ; Apoptosis ; Drug Therapy, Combination ; Drug Combinations ; Cell Line, Tumor ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
The results of pancreatic surgery in Inuit patients from Greenland 1999-2022.
Autorzy:
Almdal K; Department of Surgery, Dronning Ingrid's Hospital, Nuuk, Greenland.
Storkholm J; Department of Surgery and Transplantation, Rigshospitalet, Copenhagen, Denmark.
Bernth-Andersen S; Department of Surgery, Dronning Ingrid's Hospital, Nuuk, Greenland.
Hansen CP; Department of Surgery and Transplantation, Rigshospitalet, Copenhagen, Denmark.
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Źródło:
International journal of circumpolar health [Int J Circumpolar Health] 2023 Dec; Vol. 82 (1), pp. 2208392.
Typ publikacji:
Journal Article
MeSH Terms:
Pancreatic Neoplasms*/surgery
Pancreatic Neoplasms*/pathology
Carcinoma, Pancreatic Ductal*/surgery
Carcinoma, Pancreatic Ductal*/pathology
Humans ; Greenland/epidemiology ; Inuit ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
High overall copy number variation burden by genome-wide methylation profiling holds negative prognostic value in surgically treated pancreatic ductal adenocarcinoma.
Autorzy:
Detlefsen S; Department of Pathology, Odense University Hospital, Odense, Denmark; Odense Pancreas Center (OPAC), Odense University Hospital, Odense, Denmark; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark. Electronic address: .
Boldt HB; Department of Pathology, Odense University Hospital, Odense, Denmark; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Burton M; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.
Thomsen MM; Department of Pathology, Odense University Hospital, Odense, Denmark; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Rasmussen LG; Department of Pathology, Odense University Hospital, Odense, Denmark; Odense Pancreas Center (OPAC), Odense University Hospital, Odense, Denmark.
Ørbeck SV; Department of Pathology, Odense University Hospital, Odense, Denmark; Odense Pancreas Center (OPAC), Odense University Hospital, Odense, Denmark; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Pfeiffer P; Odense Pancreas Center (OPAC), Odense University Hospital, Odense, Denmark; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark; Department of Oncology, Odense University Hospital, Odense, Denmark.
Mortensen MB; Odense Pancreas Center (OPAC), Odense University Hospital, Odense, Denmark; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark; Department of Surgery, Upper GI and HPB Section, Odense University Hospital, Odense, Denmark.
de Stricker K; Department of Pathology, Odense University Hospital, Odense, Denmark.
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Źródło:
Human pathology [Hum Pathol] 2023 Dec; Vol. 142, pp. 68-80. Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/surgery
Carcinoma, Pancreatic Ductal*/genetics
Carcinoma, Pancreatic Ductal*/surgery
Adenocarcinoma*/pathology
Humans ; DNA Copy Number Variations ; Prognosis ; Proto-Oncogene Proteins p21(ras)/genetics ; Chromosome Aberrations ; Mutation ; DNA Methylation ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Differentiation of autoimmune pancreatitis from pancreatic adenocarcinoma using CT characteristics: a systematic review and meta-analysis.
Autorzy:
Yoon SB; Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Jeon TY; Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Moon SH; Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, 22 Gwanpyeong-ro 170 beon-gil, Dongan-gu, Anyang, Gyeonggi-do, 14068, South Korea. .
Shin DW; Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, 22 Gwanpyeong-ro 170 beon-gil, Dongan-gu, Anyang, Gyeonggi-do, 14068, South Korea.
Lee SM; Department of Radiology, Cha Gangnam Medical Center, Seoul, South Korea.
Choi MH; Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Min JH; Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Kim MJ; Department of Radiology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, South Korea.
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Źródło:
European radiology [Eur Radiol] 2023 Dec; Vol. 33 (12), pp. 9010-9021. Date of Electronic Publication: 2023 Jul 19.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:
Pancreatic Neoplasms*/diagnosis
Autoimmune Pancreatitis*/diagnostic imaging
Pancreatitis*/diagnosis
Adenocarcinoma*/pathology
Autoimmune Diseases*/diagnostic imaging
Carcinoma, Pancreatic Ductal*/diagnostic imaging
Humans ; Tomography, X-Ray Computed/methods ; Diagnosis, Differential ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Metabolomic, Proteomic, and Single-Cell Proteomic Analysis of Cancer Cells Treated with the KRAS Inhibitor MRTX1133.
Autorzy:
Orsburn BC; The Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
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Źródło:
Journal of proteome research [J Proteome Res] 2023 Dec 01; Vol. 22 (12), pp. 3703-3713. Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Proto-Oncogene Proteins p21(ras)*/genetics
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/metabolism
Humans ; Proteomics ; Mutation ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
PET/MRI for evaluation of patients with pancreatic cancer.
Autorzy:
Duncan ZN; University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Summerlin D; Department of Radiology, University of Alabama at Birmingham Medical Center, Birmingham, AL, USA.
West JT; Department of Radiology, University of Alabama at Birmingham Medical Center, Birmingham, AL, USA.
Packard AT; Department of Radiology, Mayo Clinic, Rochester, MN, USA.
Morgan DE; Department of Radiology, University of Alabama at Birmingham Medical Center, Birmingham, AL, USA.
Galgano SJ; Department of Radiology, University of Alabama at Birmingham Medical Center, Birmingham, AL, USA. .
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Źródło:
Abdominal radiology (New York) [Abdom Radiol (NY)] 2023 Dec; Vol. 48 (12), pp. 3601-3609. Date of Electronic Publication: 2023 May 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Radiopharmaceuticals*
Pancreatic Neoplasms*/diagnostic imaging
Pancreatic Neoplasms*/pathology
Humans ; Positron-Emission Tomography/methods ; Positron Emission Tomography Computed Tomography/methods ; Magnetic Resonance Imaging ; Neoplasm Staging ; Fluorodeoxyglucose F18 ; Pancreatic Neoplasms
Czasopismo naukowe

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