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Wyszukujesz frazę ""Papaverine"" wg kryterium: Temat


Tytuł :
Biotransformation of papaverine and in silico docking studies of the metabolites on human phosphodiesterase 10a.
Autorzy :
Eliwa D; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, MS, 38677, USA; Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, 31527, Egypt.
Albadry MA; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, MS, 38677, USA.
Ibrahim AS; Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, 31527, Egypt.
Kabbash A; Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, 31527, Egypt.
Meepagala K; USDA-ARS, Natural Products Utilization Research Unit, University, MS, USA.
Khan IA; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, MS, 38677, USA; Division of Pharmacognosy, Department of Biomolecular Sciences, School of Pharmacy, University of Mississippi, MS, 38677, USA.
El-Aasr M; Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, 31527, Egypt.
Ross SA; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, MS, 38677, USA; Division of Pharmacognosy, Department of Biomolecular Sciences, School of Pharmacy, University of Mississippi, MS, 38677, USA. Electronic address: .
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Źródło :
Phytochemistry [Phytochemistry] 2021 Mar; Vol. 183, pp. 112598. Date of Electronic Publication: 2020 Dec 25.
Typ publikacji :
Journal Article
MeSH Terms :
Cunninghamella*
Papaverine*
Biotransformation ; Computer Simulation ; Humans ; Phosphoric Diester Hydrolases
Czasopismo naukowe
Tytuł :
Confirmation of maximal hyperemia by the incremental dose of intracoronary papaverine.
Autorzy :
Nakayama M; Department of Cardiology, Tokyo Medical University, Tokyo, Japan. .; Cooperative Major in Advanced Biomedical Sciences, Joint Graduate School of Tokyo Women's Medical University and Waseda University, 2-2 Wakamatsucho, Shinjuku, Tokyo, 162-8480, Japan. .
Tanaka N; Department of Cardiology, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.
Yamashita J; Department of Cardiology, Tokyo Medical University, Tokyo, Japan.
Iwasaki K; Cooperative Major in Advanced Biomedical Sciences, Joint Graduate School of Tokyo Women's Medical University and Waseda University, 2-2 Wakamatsucho, Shinjuku, Tokyo, 162-8480, Japan.; Department of Modern Mechanical Engineering, Waseda University, Tokyo, Japan.
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Źródło :
Cardiovascular intervention and therapeutics [Cardiovasc Interv Ther] 2020 Oct; Vol. 35 (4), pp. 371-378. Date of Electronic Publication: 2020 Jan 14.
Typ publikacji :
Journal Article
MeSH Terms :
Myocardial Ischemia*/diagnostic imaging
Myocardial Ischemia*/drug therapy
Myocardial Ischemia*/physiopathology
Coronary Vessels/*drug effects
Fractional Flow Reserve, Myocardial/*drug effects
Hyperemia/*chemically induced
Papaverine/*administration & dosage
Vasodilator Agents/*administration & dosage
Aged ; Coronary Angiography ; Coronary Stenosis/diagnostic imaging ; Coronary Stenosis/physiopathology ; Coronary Vessels/diagnostic imaging ; Coronary Vessels/physiopathology ; Dose-Response Relationship, Drug ; Electrocardiography ; Female ; Fractional Flow Reserve, Myocardial/physiology ; Hemodynamics ; Humans ; Hyperemia/physiopathology ; Injections, Intra-Arterial/adverse effects ; Male ; Middle Aged ; Papaverine/adverse effects ; Papaverine/therapeutic use ; Percutaneous Coronary Intervention/methods ; Risk Assessment ; Tachycardia, Ventricular/chemically induced ; Tachycardia, Ventricular/diagnosis ; Vasodilator Agents/adverse effects ; Vasodilator Agents/therapeutic use
Czasopismo naukowe
Tytuł :
Papaverine inhibits α-synuclein aggregation by modulating neuroinflammation and matrix metalloproteinase-3 expression in the subacute MPTP/P mouse model of Parkinson's disease.
Autorzy :
Leem YH; Department of Molecular Medicine and Medical Research Institute, School of Medicine, Ewha Womans University, Seoul, South Korea.
Park JS; Department of Molecular Medicine and Medical Research Institute, School of Medicine, Ewha Womans University, Seoul, South Korea.
Park JE; Department of Molecular Medicine and Medical Research Institute, School of Medicine, Ewha Womans University, Seoul, South Korea.
Kim DY; Department of Molecular Medicine and Medical Research Institute, School of Medicine, Ewha Womans University, Seoul, South Korea.
Kang JL; Department of Physiology and Inflammation-Cancer Microenvironment Research Center, School of Medicine, Ewha Womans University, Seoul, South Korea.
Kim HS; Department of Molecular Medicine and Medical Research Institute, School of Medicine, Ewha Womans University, Seoul, South Korea; Department of Brain & Cognitive Sciences, Ewha Womans University, Seoul, South Korea. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Oct; Vol. 130, pp. 110576. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article
MeSH Terms :
MPTP Poisoning/*drug therapy
Matrix Metalloproteinase 3/*metabolism
Neuroprotective Agents/*therapeutic use
Papaverine/*therapeutic use
Protein Aggregation, Pathological/*drug therapy
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine ; Animals ; Astrocytes/drug effects ; Disease Models, Animal ; Dopaminergic Neurons/drug effects ; MPTP Poisoning/metabolism ; Male ; Mice, Inbred C57BL ; Microglia/drug effects ; Neuroprotective Agents/pharmacology ; Neurotoxins ; Papaverine/pharmacology ; Protein Aggregation, Pathological/metabolism ; alpha-Synuclein/metabolism
Czasopismo naukowe
Tytuł :
Comparison of the Apoptotic Effects of Topically Applied Papaverine, Diltiazem, and Nitroprusside to Internal Thoracic Artery.
Autorzy :
Unal O; Eskisehir Osmangazi University Medical Faculty Department of Cardiovascular Surgery Eskisehir Turkey Department of Cardiovascular Surgery, Eskisehir Osmangazi University Medical Faculty, Eskisehir, Turkey.; Yedikule Hospital of Pulmonary Diseases and Thoracic Surgery Department of Cardiovascular Surgery Istanbul Turkey Department of Cardiovascular Surgery, Yedikule Hospital of Pulmonary Diseases and Thoracic Surgery, Istanbul, Turkey.
Ulukan MO; Eskisehir Osmangazi University Medical Faculty Department of Cardiovascular Surgery Eskisehir Turkey Department of Cardiovascular Surgery, Eskisehir Osmangazi University Medical Faculty, Eskisehir, Turkey.; Istanbul Medipol University Medical Faculty Department of Cardiovascular Surgery Istanbul Turkey Department of Cardiovascular Surgery, Istanbul Medipol University Medical Faculty, Istanbul, Turkey.
Bakuy V; Baskent University Medical Faculty Department of Cardiovascular Surgery Ankara Turkey Department of Cardiovascular Surgery, Baskent University Medical Faculty, Ankara, Turkey.
Kaytaz B; Eskisehir Osmangazi University Medical Faculty Department of Genetics Eskisehir Turkey Department of Genetics, Eskisehir Osmangazi University Medical Faculty, Eskisehir, Turkey.
Artan S; Eskisehir Osmangazi University Medical Faculty Department of Genetics Eskisehir Turkey Department of Genetics, Eskisehir Osmangazi University Medical Faculty, Eskisehir, Turkey.
Aral E; Eskisehir Osmangazi University Medical Faculty Department of Histology and Embryology Eskisehir Turkey Department of Histology and Embryology, Eskisehir Osmangazi University Medical Faculty, Eskisehir, Turkey.
Oztas DM; Bagcilar Education and Research Hospital Cardiovascular Surgery Clinic Istanbul Turkey Cardiovascular Surgery Clinic, Bagcilar Education and Research Hospital, Istanbul, Turkey.
Beyaz MO; Istanbul Medipol University Medical Faculty Department of Cardiovascular Surgery Istanbul Turkey Department of Cardiovascular Surgery, Istanbul Medipol University Medical Faculty, Istanbul, Turkey.
Ugurlucan M; Istanbul Medipol University Medical Faculty Department of Cardiovascular Surgery Istanbul Turkey Department of Cardiovascular Surgery, Istanbul Medipol University Medical Faculty, Istanbul, Turkey.
Sevin B; Eskisehir Osmangazi University Medical Faculty Department of Cardiovascular Surgery Eskisehir Turkey Department of Cardiovascular Surgery, Eskisehir Osmangazi University Medical Faculty, Eskisehir, Turkey.
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Źródło :
Brazilian journal of cardiovascular surgery [Braz J Cardiovasc Surg] 2020 Oct 01; Vol. 35 (5), pp. 626-633. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mammary Arteries*
Diltiazem/*therapeutic use
Nitroprusside/*therapeutic use
Papaverine/*therapeutic use
Vasodilator Agents/*therapeutic use
Diltiazem/pharmacology ; Humans ; Nitroprusside/pharmacology ; Papaverine/pharmacology ; Vasodilator Agents/pharmacology
Czasopismo naukowe
Tytuł :
Local Intra-arterial Vasodilator Infusion in Non-Occlusive Mesenteric Ischemia Significantly Increases Survival Rate.
Autorzy :
Winzer R; Institute and Policlinic for Diagnostic and Interventional Radiology, University Hospital, Carl Gustav Carus University, TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany. .
Fedders D; Institute and Policlinic for Diagnostic and Interventional Radiology, University Hospital, Carl Gustav Carus University, TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Backes M; Institute and Policlinic for Diagnostic and Interventional Radiology, University Hospital, Carl Gustav Carus University, TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Ittermann T; Institute for Community Medicine, University Medicine Greifswald, Domstraße 11, 17489, Greifswald, Germany.
Gründling M; Department of Anesthesia and Intensive Care, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, 17475, Greifswald, Germany.
Mensel B; Zentrum für Diagnostische/Interventionelle Radiologie Und Neuroradiologie, Zentralklinik Bad Berka, Robert-Koch-Allee 9, 99438, Bad Berka, Germany.
Held HC; Visceral, Thoracic and Vascular Surgery, Carl Gustav Carus University, TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Kromrey ML; Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, 17475, Greifswald, Germany.
Weitz J; Visceral, Thoracic and Vascular Surgery, Carl Gustav Carus University, TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Hoffmann RT; Institute and Policlinic for Diagnostic and Interventional Radiology, University Hospital, Carl Gustav Carus University, TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Bülow R; Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, 17475, Greifswald, Germany.
Kühn JP; Institute and Policlinic for Diagnostic and Interventional Radiology, University Hospital, Carl Gustav Carus University, TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
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Źródło :
Cardiovascular and interventional radiology [Cardiovasc Intervent Radiol] 2020 Aug; Vol. 43 (8), pp. 1148-1155. Date of Electronic Publication: 2020 May 22.
Typ publikacji :
Journal Article
MeSH Terms :
Mesenteric Ischemia/*drug therapy
Papaverine/*administration & dosage
Vasodilator Agents/*administration & dosage
Aged ; Female ; Humans ; Infusions, Intra-Arterial ; Kaplan-Meier Estimate ; Male ; Papaverine/therapeutic use ; Retrospective Studies ; Survival Rate ; Treatment Outcome ; Vasodilator Agents/therapeutic use
Czasopismo naukowe
Tytuł :
Combined effect of left stellate ganglion blockade and topical administration of papaverine on left internal thoracic artery blood flow in patients undergoing coronary revascularization.
Autorzy :
Chandran R; Department of Cardiac Anaesthesia, Freeman Hospital, Newcastle Upon Tyne, UK.
Sreedhar R; Department of Anesthesia, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.
Gadhinglajkar S; Department of Anesthesia, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.
Dash P; Department of Anesthesia, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.
Karunakaran J; Department of CVTS, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.
Pillai V; Department of CVTS, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.
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Źródło :
Annals of cardiac anaesthesia [Ann Card Anaesth] 2020 Apr-Jun; Vol. 23 (2), pp. 170-176.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Stellate Ganglion*
Coronary Artery Bypass/*methods
Mammary Arteries/*drug effects
Nerve Block/*methods
Papaverine/*pharmacology
Vasodilator Agents/*pharmacology
Administration, Topical ; Adult ; Aged ; Blood Flow Velocity/drug effects ; Cardiopulmonary Bypass ; Coronary Circulation/drug effects ; Female ; Humans ; Male ; Middle Aged ; Papaverine/administration & dosage ; Prospective Studies ; Vascular Patency/drug effects ; Vasodilator Agents/administration & dosage
Czasopismo naukowe
Tytuł :
The phosphodiesterase 10 inhibitor papaverine exerts anti-inflammatory and neuroprotective effects via the PKA signaling pathway in neuroinflammation and Parkinson's disease mouse models.
Autorzy :
Lee YY; Department of Molecular Medicine and Tissue Injury Defense Research Center, School of Medicine, Ewha Womans University, 808-1 Magok-dong, Gangseo-gu, Seoul, 07804, South Korea.
Park JS; Department of Molecular Medicine and Tissue Injury Defense Research Center, School of Medicine, Ewha Womans University, 808-1 Magok-dong, Gangseo-gu, Seoul, 07804, South Korea.
Leem YH; Department of Molecular Medicine and Tissue Injury Defense Research Center, School of Medicine, Ewha Womans University, 808-1 Magok-dong, Gangseo-gu, Seoul, 07804, South Korea.
Park JE; Department of Molecular Medicine and Tissue Injury Defense Research Center, School of Medicine, Ewha Womans University, 808-1 Magok-dong, Gangseo-gu, Seoul, 07804, South Korea.
Kim DY; Department of Molecular Medicine and Tissue Injury Defense Research Center, School of Medicine, Ewha Womans University, 808-1 Magok-dong, Gangseo-gu, Seoul, 07804, South Korea.
Choi YH; Department of Physiology and Tissue Injury Defense Research Center, School of Medicine, Ewha Womans University, Seoul, South Korea.
Park EM; Department of Pharmacology and Tissue Injury Defense Research Center, School of Medicine, Ewha Womans University, Seoul, South Korea.; Department of Brain & Cognitive Sciences, Ewha Womans University, Seoul, South Korea.
Kang JL; Department of Physiology and Tissue Injury Defense Research Center, School of Medicine, Ewha Womans University, Seoul, South Korea.
Kim HS; Department of Molecular Medicine and Tissue Injury Defense Research Center, School of Medicine, Ewha Womans University, 808-1 Magok-dong, Gangseo-gu, Seoul, 07804, South Korea. .; Department of Brain & Cognitive Sciences, Ewha Womans University, Seoul, South Korea. .
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Źródło :
Journal of neuroinflammation [J Neuroinflammation] 2019 Dec 02; Vol. 16 (1), pp. 246. Date of Electronic Publication: 2019 Dec 02.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*therapeutic use
Cyclic AMP-Dependent Protein Kinases/*metabolism
Neuroprotective Agents/*therapeutic use
Papaverine/*therapeutic use
Parkinsonian Disorders/*prevention & control
Phosphodiesterase Inhibitors/*therapeutic use
Animals ; Anti-Inflammatory Agents/pharmacology ; Cell Line, Transformed ; Cyclic AMP-Dependent Protein Kinases/antagonists & inhibitors ; Lipopolysaccharides/toxicity ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Inbred ICR ; Neuroprotective Agents/pharmacology ; Papaverine/pharmacology ; Parkinsonian Disorders/chemically induced ; Parkinsonian Disorders/enzymology ; Phosphodiesterase Inhibitors/pharmacology ; Phosphoric Diester Hydrolases/metabolism ; Random Allocation ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Vasodilation by Verapamil-Nitroglycerin Solution in Microvascular Surgery.
Autorzy :
Seth R; Department of Otolaryngology-Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.
Badran KW; Department of Otolaryngology-Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.; Department of Otolaryngology-Head and Neck Surgery, University of California-Los Angeles, Los Angeles, California, USA.
Cedars E; Department of Otolaryngology-Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.
Plonowska K; Department of Otolaryngology-Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.
Benjamin T; Department of Otolaryngology-Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.
Saggi S; Department of Otolaryngology-Head and Neck Surgery, University of California-Los Angeles, Los Angeles, California, USA.
Knott PD; Department of Otolaryngology-Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.
Heaton CM; Department of Otolaryngology-Head and Neck Surgery, University of California-San Francisco, San Francisco, California, USA.
Blackwell KE; Department of Otolaryngology-Head and Neck Surgery, University of California-Los Angeles, Los Angeles, California, USA.
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Źródło :
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery [Otolaryngol Head Neck Surg] 2021 Jan; Vol. 164 (1), pp. 104-109. Date of Electronic Publication: 2020 Jul 07.
Typ publikacji :
Journal Article
MeSH Terms :
Microsurgery*
Vascular Surgical Procedures*
Head and Neck Neoplasms/*surgery
Nitroglycerin/*pharmacology
Surgical Flaps/*blood supply
Vasodilation/*drug effects
Verapamil/*pharmacology
Administration, Topical ; Graft Rejection ; Humans ; Nitroglycerin/administration & dosage ; Papaverine/pharmacology ; Retrospective Studies ; Solutions ; Verapamil/administration & dosage
Czasopismo naukowe
Tytuł :
Trimebutine attenuates high mobility group box 1-receptor for advanced glycation end-products inflammatory signaling pathways.
Autorzy :
Nakajima S; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan.
Ogawa N; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan.
Yokoue N; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan.
Tachibana H; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan.
Tamada K; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan.
Okazawa M; Department of Genomic Medicinal Science, Research Institute for Science and Technology, Organization for Research Advancement, Tokyo University of Science, Noda, Chiba, 278-8510, Japan.
Sato A; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan.
Oyama T; Hinoki Shinyaku Co. Ltd., Chiyoda-ku, Tokyo, 102-0084, Japan.
Abe H; Hinoki Shinyaku Co. Ltd., Chiyoda-ku, Tokyo, 102-0084, Japan.
Kamiya T; Hinoki Shinyaku Co. Ltd., Chiyoda-ku, Tokyo, 102-0084, Japan.
Yoshimori A; Institute for Theoretical Medicine Inc., Fujisawa, Kanagawa, 251-0012, Japan.
Yoshizawa K; Laboratory of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan.
Inoue S; Department of Emergency and Critical Care Medicine, Tokai University School of Medicine, Isehara, Kanagawa, 259-1193, Japan.
Yokomizo T; Department of Biochemistry, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, 113-8421, Japan.
Uchiumi F; Department of Gene Regulation, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan.
Abe T; Hinoki Shinyaku Co. Ltd., Chiyoda-ku, Tokyo, 102-0084, Japan.
Tanuma SI; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, 278-8510, Japan; Department of Genomic Medicinal Science, Research Institute for Science and Technology, Organization for Research Advancement, Tokyo University of Science, Noda, Chiba, 278-8510, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Dec 17; Vol. 533 (4), pp. 1155-1161. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
HMGB1 Protein/*metabolism
MAP Kinase Signaling System/*drug effects
Receptor for Advanced Glycation End Products/*metabolism
Trimebutine/*pharmacology
Animals ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation/pathology ; Interleukin-6/metabolism ; Janus Kinases/antagonists & inhibitors ; Macrophages ; Mice ; Papaverine/chemistry ; Papaverine/pharmacology ; RAW 264.7 Cells ; Trimebutine/chemistry ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Reaction of Papaverine with Baran Diversinates .
Autorzy :
Egbewande FA; Griffith Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia. .
Coster MJ; Griffith Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia. .
Jenkins ID; Griffith Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia. .
Davis RA; Griffith Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia. .
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2019 Oct 31; Vol. 24 (21). Date of Electronic Publication: 2019 Oct 31.
Typ publikacji :
Journal Article
MeSH Terms :
Papaverine/*chemistry
Sulfinic Acids/*chemistry
Carbon-13 Magnetic Resonance Spectroscopy ; Electrons ; Models, Molecular ; Papaverine/analogs & derivatives ; Proton Magnetic Resonance Spectroscopy
Czasopismo naukowe
Tytuł :
Effectiveness and safety of intracoronary papaverine, alprostadil, and high dosages of nicorandil and adenosine triphosphate for measurement of the index of coronary microcirculatory resistance in a pig model.
Autorzy :
Duan T; Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; Department of Cardiology, Guangzhou General Hospital of Guangzhou Military Command, China.
Zhang J; Department of Cardiology, Guangzhou General Hospital of Guangzhou Military Command, China.
Xiang D; Department of Cardiology, Guangzhou General Hospital of Guangzhou Military Command, China.
Song R; Department of Cardiology, Guangzhou General Hospital of Guangzhou Military Command, China.
Kong R; Department of Cardiology, Guangzhou General Hospital of Guangzhou Military Command, China.
Xu D; Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
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Źródło :
Advances in clinical and experimental medicine : official organ Wroclaw Medical University [Adv Clin Exp Med] 2019 Oct; Vol. 28 (10), pp. 1409-1418.
Typ publikacji :
Journal Article
MeSH Terms :
Adenosine Triphosphate/*administration & dosage
Alprostadil/*administration & dosage
Coronary Circulation/*drug effects
Microcirculation/*drug effects
Nicorandil/*administration & dosage
Papaverine/*administration & dosage
Vasodilator Agents/*administration & dosage
Adenosine Triphosphate/pharmacology ; Alprostadil/pharmacology ; Animals ; Papaverine/pharmacology ; Swine ; Vasodilator Agents/pharmacology
Czasopismo naukowe
Tytuł :
A SARS-CoV-2 cytopathicity dataset generated by high-content screening of a large drug repurposing collection.
Autorzy :
Ellinger B; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg, 22525, Germany. .
Bojkova D; University Hospital Frankfurt, 60590, Frankfurt am Main, Germany.
Zaliani A; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg, 22525, Germany.
Cinatl J; University Hospital Frankfurt, 60590, Frankfurt am Main, Germany.
Claussen C; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg, 22525, Germany.; Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, 60596, Germany.
Westhaus S; University Hospital Frankfurt, 60590, Frankfurt am Main, Germany.
Keminer O; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg, 22525, Germany.
Reinshagen J; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg, 22525, Germany.
Kuzikov M; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg, 22525, Germany.
Wolf M; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg, 22525, Germany.
Geisslinger G; Pharmazentrum Frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, 60590, Frankfurt am Main, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, 60596, Frankfurt am Main, Germany.; Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, 60596, Germany.
Gribbon P; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg, 22525, Germany.; Fraunhofer Cluster of Excellence for Immune Mediated Diseases CIMD, Frankfurt am Main, 60596, Germany.
Ciesek S; University Hospital Frankfurt, 60590, Frankfurt am Main, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, 60596, Frankfurt am Main, Germany.; DZIF, German Centre for Infection Research, External partner site, 60596, Frankfurt am Main, Germany.
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Źródło :
Scientific data [Sci Data] 2021 Feb 26; Vol. 8 (1), pp. 70. Date of Electronic Publication: 2021 Feb 26.
Typ publikacji :
Dataset; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Repositioning*
Antiviral Agents/*pharmacology
SARS-CoV-2/*drug effects
COVID-19 ; Caco-2 Cells ; Cetylpyridinium ; Drug Evaluation, Preclinical ; Esters ; Guanidines ; Humans ; Lopinavir ; Mefloquine ; Papaverine
Czasopismo naukowe
Tytuł :
Pluripotent anti-inflammatory immunomodulatory effects of papaverine against cerebral ischemic-reperfusion injury.
Autorzy :
Guan S; Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Liu Q; Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Gu H; Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Zhang YY; Geriatric Department, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Dongzhimen, Beijing 100007, China.
Wei PL; Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Qi YF; Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Liu J; Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address: .
Wang Z; Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address: .
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2020 Oct; Vol. 144 (2), pp. 69-75. Date of Electronic Publication: 2020 Jul 17.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents*
Immunologic Factors*
Brain Ischemia/*drug therapy
Brain Ischemia/*genetics
Papaverine/*pharmacology
Papaverine/*therapeutic use
Reperfusion Injury/*drug therapy
Reperfusion Injury/*genetics
Animals ; Cytokines/genetics ; Cytokines/metabolism ; Disease Models, Animal ; Gene Expression/drug effects ; Gene Expression/genetics ; HMGB1 Protein/genetics ; HMGB1 Protein/metabolism ; Inflammation ; Interleukin-17/genetics ; Interleukin-17/metabolism ; Male ; Mice, Inbred Strains ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Signal Transduction/drug effects ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
The Impact of Intra-Arterial Papaverine-Hydrochloride on Cerebral Metabolism and Oxygenation for Treatment of Delayed-Onset Post-Subarachnoid Hemorrhage Vasospasm.
Autorzy :
Hosmann A; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Wang WT; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Dodier P; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Bavinzski G; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Engel A; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Herta J; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Plöchl W; Department of Anesthesia, General Intensive Care Medicine and Pain Management, Medical University of Vienna, Vienna, Austria.
Reinprecht A; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Gruber A; Department of Neurosurgery, Kepler Universitätsklinikum, Johannes Kepler University Linz, Linz, Austria.
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Źródło :
Neurosurgery [Neurosurgery] 2020 Sep 15; Vol. 87 (4), pp. 712-719.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*drug effects
Brain/*metabolism
Papaverine/*administration & dosage
Subarachnoid Hemorrhage/*complications
Vasodilator Agents/*administration & dosage
Vasospasm, Intracranial/*etiology
Adult ; Cerebrovascular Circulation ; Endovascular Procedures/adverse effects ; Endovascular Procedures/methods ; Female ; Humans ; Injections, Intra-Arterial ; Male ; Microdialysis ; Middle Aged ; Subarachnoid Hemorrhage/surgery
Czasopismo naukowe
Tytuł :
Using Papaverine and Its Metabolites, 6-Desmethyl Papaverine and 4',6-Didesmethyl Papaverine as Biomarkers to Improve the Detection Time of Heroin Use.
Autorzy :
Wolf CE; Pathology.
Pierce KL; Clinical Laboratory Sciences.
Goldfine BL; Clinical Laboratory Sciences.
Nanco CR; Pathology.
Poklis JL; Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA.
Korzun WJ; Clinical Laboratory Sciences.
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Źródło :
Journal of analytical toxicology [J Anal Toxicol] 2019 Sep 10; Vol. 43 (8), pp. 600-606.
Typ publikacji :
Journal Article
MeSH Terms :
Heroin Dependence/*urine
Papaverine/*analogs & derivatives
Substance Abuse Detection/*methods
Biomarkers/urine ; Chromatography, High Pressure Liquid ; Humans ; Limit of Detection ; Papaverine/urine ; Reproducibility of Results ; Substance Abuse Detection/instrumentation ; Substance Abuse Detection/standards ; Tandem Mass Spectrometry ; Time Factors
Czasopismo naukowe
Tytuł :
Novel Papaverine Metal Complexes with Potential Anticancer Activities.
Autorzy :
Gaber A; Department of Biology, College of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Alsanie WF; Department of Clinical Laboratories, College of Applied Medical Sciences, P.O. Box 11099, Taif 21944, Saudi Arabia.
Kumar DN; Department of Chemistry, Deshbandhu College, University of Delhi, Delhi 110019, India.
Refat MS; Department of Chemistry, College of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.; Department of Chemistry, Faculty of Science, Port Said University, Port Said 42511, Egypt.
Saied EM; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.; Institute for Chemistry, Humboldt Universität zu Berlin, Brook-Taylor-Str. 2, 12489 Berlin, Germany.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Nov 20; Vol. 25 (22). Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*chemistry
Antineoplastic Agents/*pharmacology
Coordination Complexes/*chemistry
Papaverine/*chemistry
Animals ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Anti-Infective Agents/chemistry ; Anti-Infective Agents/pharmacology ; Antineoplastic Agents/chemical synthesis ; Cell Line, Tumor ; Cell Survival/drug effects ; Chemistry Techniques, Synthetic ; Humans ; Magnetic Resonance Spectroscopy ; Microbial Sensitivity Tests ; Molecular Structure ; Nanostructures/chemistry ; Nanostructures/ultrastructure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Identification and characterization of cytochrome P450 1232A24 and 1232F1 from Arthrobacter sp. and their role in the metabolic pathway of papaverine.
Autorzy :
Klenk JM; Department of Technical Biochemistry, Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, Allmandring 31, Stuttgart, Germany.
Fischer MP; Department of Technical Biochemistry, Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, Allmandring 31, Stuttgart, Germany.
Dubiel P; Department of Chemistry, University of York, Heslington, York, UK.
Sharma M; Department of Chemistry, University of York, Heslington, York, UK.
Rowlinson B; Department of Chemistry, University of York, Heslington, York, UK.
Grogan G; Department of Chemistry, University of York, Heslington, York, UK.
Hauer B; Department of Technical Biochemistry, Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, Allmandring 31, Stuttgart, Germany.
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Źródło :
Journal of biochemistry [J Biochem] 2019 Jul 01; Vol. 166 (1), pp. 51-66.
Typ publikacji :
Journal Article
MeSH Terms :
Arthrobacter/*enzymology
Cytochrome P-450 Enzyme System/*metabolism
Papaverine/*metabolism
Biocatalysis ; Cytochrome P-450 Enzyme System/analysis ; Molecular Structure ; Oxidation-Reduction ; Papaverine/chemistry
Czasopismo naukowe
Tytuł :
Papaverine use for radial artery sheath entrapment.
Autorzy :
Sciahbasi A; Department of Interventional Cardiology, Sandro Pertini Hospital; Rome-Italy.
Cuono A; Department of Cardiovascular Diseases, Sant'Andrea Hospital of Rome; Rome-Italy.
Marrangoni A; University of L'Aquila; L'Aquila-Italy.
Rigattieri S; Department of Cardiovascular Diseases, Sant'Andrea Hospital of Rome; Rome-Italy.
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Źródło :
Anatolian journal of cardiology [Anatol J Cardiol] 2019 Jun; Vol. 22 (1), pp. 44-45.
Typ publikacji :
Journal Article
MeSH Terms :
Papaverine/*therapeutic use
Percutaneous Coronary Intervention/*adverse effects
Peripheral Arterial Disease/*complications
Radial Artery/*drug effects
Spasm/*complications
Vasodilator Agents/*therapeutic use
Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Papaverine/administration & dosage ; Peripheral Arterial Disease/drug therapy ; Retrospective Studies ; Spasm/drug therapy ; Vasodilator Agents/administration & dosage
Czasopismo naukowe
Tytuł :
Coupling of micro-solid-phase extraction and internal extractive electrospray ionization mass spectrometry for ultra-sensitive detection of 1-hydroxypyrene and papaverine in human urine samples.
Autorzy :
Han J; State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, 130012, China.; Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China University of Technology, Nanchang, 330013, China.
Liu W; Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China University of Technology, Nanchang, 330013, China.
Su R; State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, 130012, China.
Zhu L; State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, 130012, China.
Wu D; Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China University of Technology, Nanchang, 330013, China. .
Xu J; Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China University of Technology, Nanchang, 330013, China.
Liu A; State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, 130012, China.
Zhang H; State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, 130012, China.
Kou W; State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, 130012, China.
Zhang X; Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China University of Technology, Nanchang, 330013, China.
Yang S; Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China University of Technology, Nanchang, 330013, China.
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Źródło :
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2019 Jun; Vol. 411 (15), pp. 3281-3290. Date of Electronic Publication: 2019 Apr 15.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Papaverine/*urine
Pyrenes/*urine
Solid Phase Microextraction/*instrumentation
Spectrometry, Mass, Electrospray Ionization/*instrumentation
Vasodilator Agents/*urine
Adsorption ; Biomarkers/urine ; Equipment Design ; Humans ; Limit of Detection ; Papaverine/isolation & purification ; Pyrenes/isolation & purification ; Reproducibility of Results ; Solid Phase Microextraction/methods ; Spectrometry, Mass, Electrospray Ionization/methods ; Tandem Mass Spectrometry/instrumentation ; Tandem Mass Spectrometry/methods ; Vasodilator Agents/isolation & purification
Czasopismo naukowe
Tytuł :
Anticancer effects of a non-narcotic opium alkaloid medicine, papaverine, in human glioblastoma cells.
Autorzy :
Inada M; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, Japan.
Shindo M; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, Japan.; National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.
Kobayashi K; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, Japan.
Sato A; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, Japan.
Yamamoto Y; Department of Neurosurgery, Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Akasaki Y; Department of Neurosurgery, Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Ichimura K; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.
Tanuma SI; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba, Japan.; Department of Genomic Medicinal Science, Research Institute for Science and Technology, Organization for Research Advancement, Tokyo University of Science, Noda, Chiba, Japan.
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Źródło :
PloS one [PLoS One] 2019 May 17; Vol. 14 (5), pp. e0216358. Date of Electronic Publication: 2019 May 17 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Glioblastoma/*drug therapy
Papaverine/*therapeutic use
Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Glioblastoma/pathology ; HMGB1 Protein/metabolism ; Heterografts ; Humans ; Mice ; Opiate Alkaloids ; Papaverine/pharmacology ; Receptor for Advanced Glycation End Products/metabolism ; Temozolomide/pharmacology
Czasopismo naukowe

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