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Wyszukujesz frazę ""Papillomavirus E7 Proteins"" wg kryterium: Temat


Tytuł:
Evidence for direct interaction between the oncogenic proteins E6 and E7 of high-risk human papillomavirus (HPV).
Autorzy:
Lim J; Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, Tuebingen, Germany.
Lilie H; Institute of Biochemistry and Biotechnology, Martin-Luther-University Halle-Wittemberg, Halle-Wittemberg, Germany.
Kalbacher H; Interfaculty Institute of Biochemistry, Eberhard-Karls-University Tuebingen, Tuebingen, Germany.
Roos N; Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, Tuebingen, Germany.
Frecot DI; Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, Tuebingen, Germany.
Feige M; Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, Tuebingen, Germany.
Conrady M; Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, Tuebingen, Germany.
Votteler T; Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, Tuebingen, Germany.
Cousido-Siah A; Equipe Labellisée Ligue 2015, Department of Integrative Biology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS, INSERM, UdS, Illkirch, France.
Corradini Bartoli G; Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, Tuebingen, Germany.
Iftner T; Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, Tuebingen, Germany. Electronic address: .
Trave G; Equipe Labellisée Ligue 2015, Department of Integrative Biology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS, INSERM, UdS, Illkirch, France.
Simon C; Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, Tuebingen, Germany. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 Aug; Vol. 299 (8), pp. 104954. Date of Electronic Publication: 2023 Jun 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Human papillomavirus 16*/genetics
Human papillomavirus 16*/metabolism
Oncogene Proteins, Viral*/genetics
Oncogene Proteins, Viral*/metabolism
Papillomavirus E7 Proteins*/genetics
Papillomavirus E7 Proteins*/metabolism
Papillomavirus Infections*
Animals ; Humans ; Carcinogenesis ; Human Papillomavirus Viruses ; Neoplasms
Czasopismo naukowe
Tytuł:
MAL expression downregulation through suppressive H3K27me3 marks at the promoter in HPV16-related cervical cancers is prognostically relevant and manifested by the interplay of novel MAL antisense long noncoding RNA AC103563.8, E7 oncoprotein and EZH2.
Autorzy:
Sinha A; National Institute of Biomedical Genomics, P.O.: N.S.S, Kalyani, 741251, West Bengal, India.
Ghosh A; National Institute of Biomedical Genomics, P.O.: N.S.S, Kalyani, 741251, West Bengal, India.
Ghosh A; National Institute of Biomedical Genomics, P.O.: N.S.S, Kalyani, 741251, West Bengal, India.
Mathai S; Tata Medical Center, Kolkata, West Bengal, India.
Bhaumik J; Tata Medical Center, Kolkata, West Bengal, India.
Mukhopadhyay A; Kolkata Gynecological Oncology Trials and Translational Research Group, Kolkata, West Bengal, India.
Maitra A; National Institute of Biomedical Genomics, P.O.: N.S.S, Kalyani, 741251, West Bengal, India.
Biswas NK; National Institute of Biomedical Genomics, P.O.: N.S.S, Kalyani, 741251, West Bengal, India.
Sengupta S; National Institute of Biomedical Genomics, P.O.: N.S.S, Kalyani, 741251, West Bengal, India. .
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Źródło:
Clinical epigenetics [Clin Epigenetics] 2024 Mar 10; Vol. 16 (1), pp. 40. Date of Electronic Publication: 2024 Mar 10.
Typ publikacji:
Journal Article
MeSH Terms:
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Uterine Cervical Neoplasms*/pathology
Oncogene Proteins, Viral*/genetics
Oncogene Proteins, Viral*/metabolism
Female ; Humans ; Histones/metabolism ; Down-Regulation ; Human papillomavirus 16/genetics ; DNA Methylation ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/metabolism ; Chromatin/metabolism ; Enhancer of Zeste Homolog 2 Protein/genetics ; Enhancer of Zeste Homolog 2 Protein/metabolism
Czasopismo naukowe
Tytuł:
Evaluation of the anti-cancer efficacy of lipid nanoparticles containing siRNA against HPV16 E6/E7 combined with cisplatin in a xenograft model of cervical cancer.
Autorzy:
Kang SW; Department of Obstetrics & Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Asan Preclinical Evaluation Center for Cancer TherapeutiX, Asan Medical Center, Seoul, Republic of Korea.
Kang OJ; Department of Obstetrics & Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Asan Preclinical Evaluation Center for Cancer TherapeutiX, Asan Medical Center, Seoul, Republic of Korea.
Lee JY; Department of Obstetrics & Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Asan Preclinical Evaluation Center for Cancer TherapeutiX, Asan Medical Center, Seoul, Republic of Korea.
Kim H; EnhancedBio Inc., Seoul, Republic of Korea.
Jung H; EnhancedBio Inc., Seoul, Republic of Korea.
Kim H; EnhancedBio Inc., Seoul, Republic of Korea.
Lee SW; Department of Obstetrics & Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Asan Preclinical Evaluation Center for Cancer TherapeutiX, Asan Medical Center, Seoul, Republic of Korea.
Kim YM; Department of Obstetrics & Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Asan Preclinical Evaluation Center for Cancer TherapeutiX, Asan Medical Center, Seoul, Republic of Korea.
Choi EK; Asan Preclinical Evaluation Center for Cancer TherapeutiX, Asan Medical Center, Seoul, Republic of Korea.; Department of Radiation Oncology, ASAN Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
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Źródło:
PloS one [PLoS One] 2024 Feb 16; Vol. 19 (2), pp. e0298815. Date of Electronic Publication: 2024 Feb 16 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Uterine Cervical Neoplasms*/drug therapy
Uterine Cervical Neoplasms*/genetics
Uterine Cervical Neoplasms*/pathology
Oncogene Proteins, Viral*/genetics
Oncogene Proteins, Viral*/metabolism
Liposomes*
Nanoparticles*
Female ; Humans ; Animals ; Mice ; RNA, Small Interfering/genetics ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Human papillomavirus 16/genetics ; Human papillomavirus 16/metabolism ; Tumor Suppressor Protein p53/genetics ; Mice, Nude ; Heterografts ; Cell Line, Tumor ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/metabolism ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł:
ErbB2/HER2 receptor tyrosine kinase regulates human papillomavirus promoter activity.
Autorzy:
Mikuličić S; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Shamun M; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Massenberg A; University of Bonn, Faculty of Mathematics and Natural Sciences, Life & Medical Sciences (LIMES) Institute, Bonn, Rheinland-Pfalz, Germany.
Franke AL; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Freitag K; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Döring T; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Strunk J; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Tenzer S; Institute for Immunology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Rheinland-Pfalz, Germany.; Helmholtz Institute for Translational Oncology (HI-TRON) Mainz, Mainz, Rheinland-Pfalz, Germany.
Lang T; University of Bonn, Faculty of Mathematics and Natural Sciences, Life & Medical Sciences (LIMES) Institute, Bonn, Rheinland-Pfalz, Germany.
Florin L; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
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Źródło:
Frontiers in immunology [Front Immunol] 2024 Feb 02; Vol. 15, pp. 1335302. Date of Electronic Publication: 2024 Feb 02 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Oncogene Proteins, Viral*/genetics
Oncogene Proteins, Viral*/metabolism
Papillomavirus Infections*/metabolism
Female ; Humans ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/metabolism ; Human Papillomavirus Viruses ; Cell Line, Tumor ; Proto-Oncogene Proteins c-akt/metabolism ; Proteomics ; Repressor Proteins/metabolism ; Human papillomavirus 16/metabolism ; Papillomaviridae/genetics ; Receptor Protein-Tyrosine Kinases/metabolism
Czasopismo naukowe
Tytuł:
Computational and AI-driven 3D structural analysis of human papillomavirus (HPV) oncoproteins E5, E6, and E7 reveal significant divergence of HPV E5 between low-risk and high-risk genotypes.
Autorzy:
Jones RN; Department of Radiation Medicine and Applied Sciences, University of California, San Diego, La Jolla, CA, 92037, USA.
Miyauchi S; Department of Radiation Medicine and Applied Sciences, University of California, San Diego, La Jolla, CA, 92037, USA.
Roy S; Department of Radiation Medicine and Applied Sciences, University of California, San Diego, La Jolla, CA, 92037, USA.
Boutros N; Department of Radiation Medicine and Applied Sciences, University of California, San Diego, La Jolla, CA, 92037, USA.
Mayadev JS; Department of Radiation Medicine and Applied Sciences, University of California, San Diego, La Jolla, CA, 92037, USA.
Mell LK; Department of Radiation Medicine and Applied Sciences, University of California, San Diego, La Jolla, CA, 92037, USA; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Califano JA; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA; Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of California, San Diego, La Jolla, CA, USA.
Venuti A; HPV-UNIT-UOSD Tumor Immunology and Immunotherapy, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Sharabi AB; Department of Radiation Medicine and Applied Sciences, University of California, San Diego, La Jolla, CA, 92037, USA; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA. Electronic address: .
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Źródło:
Virology [Virology] 2024 Feb; Vol. 590, pp. 109946. Date of Electronic Publication: 2023 Dec 11.
Typ publikacji:
Journal Article
MeSH Terms:
Oncogene Proteins, Viral*/genetics
Oncogene Proteins, Viral*/metabolism
Papillomavirus Infections*
Humans ; Human Papillomavirus Viruses ; Artificial Intelligence ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/metabolism ; Papillomaviridae/genetics ; Genotype
Czasopismo naukowe
Tytuł:
Genetic and epigenetic alterations in DNA repair genes and treatment outcome of chemoradiotherapy in cervical cancer.
Autorzy:
Kushwah AS; Department of Urology and Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Ave, New York 10029, NY, USA; Molecular & Human Genetics Laboratory, Department of Zoology, University of Lucknow, Lucknow 226007, Uttar Pradesh, India; Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi 221005, Uttar Pradesh, India.
Masood S; Molecular & Human Genetics Laboratory, Department of Zoology, University of Lucknow, Lucknow 226007, Uttar Pradesh, India.
Mishra R; Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi 221005, Uttar Pradesh, India.
Banerjee M; Molecular & Human Genetics Laboratory, Department of Zoology, University of Lucknow, Lucknow 226007, Uttar Pradesh, India. Electronic address: .
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Źródło:
Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2024 Feb; Vol. 194, pp. 104240. Date of Electronic Publication: 2023 Dec 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Uterine Cervical Neoplasms*/genetics
Uterine Cervical Neoplasms*/therapy
Uterine Cervical Neoplasms*/pathology
Oncogene Proteins, Viral*/genetics
Oncogene Proteins, Viral*/metabolism
Papillomavirus Infections*/complications
Papillomavirus Infections*/genetics
Papillomavirus Infections*/pathology
Humans ; Female ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/metabolism ; DNA ; DNA Repair/genetics ; Epigenesis, Genetic ; Treatment Outcome
Czasopismo naukowe
Tytuł:
The difference of transcriptome of HPV-infected patients contributes more to the occurrence of cervical cancer than the mutations of E6 and E7 genes in HPV16.
Autorzy:
Zhang L; Department of Gynaecology, The Second Norman Bethune Hospital of Jilin University, Changchun, China.
Li M; Department of Regenerative Medicine, School of Pharmaceutical Science, Jilin University, Changchun, China.
Yuan F; Department of Gynaecology, The Second Norman Bethune Hospital of Jilin University, Changchun, China.
Jiang J; Department of Regenerative Medicine, School of Pharmaceutical Science, Jilin University, Changchun, China.
Zhang X; Department of Regenerative Medicine, School of Pharmaceutical Science, Jilin University, Changchun, China.
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Źródło:
Medicine [Medicine (Baltimore)] 2024 Jan 19; Vol. 103 (3), pp. e36822.
Typ publikacji:
Journal Article
MeSH Terms:
Uterine Cervical Neoplasms*/complications
Papillomavirus Infections*/complications
Papillomavirus Infections*/genetics
Oncogene Proteins, Viral*/genetics
Oncogene Proteins, Viral*/metabolism
Female ; Humans ; Human papillomavirus 16/genetics ; Human Papillomavirus Viruses ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/metabolism ; Transcriptome ; Mutation
Czasopismo naukowe
Tytuł:
Evaluation of the proteomic landscape of HPV E7‑induced alterations in human keratinocytes reveal therapeutically relevant pathways for cervical cancer.
Autorzy:
Gandhi S; Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Mohamad Razif MF; Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Othman S; Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Chakraborty S; Translational System Biology Laboratory, Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka 1000, People's Republic of Bangladesh.
Nor Rashid N; Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2023 Feb; Vol. 27 (2). Date of Electronic Publication: 2023 Jan 12.
Typ publikacji:
Journal Article
MeSH Terms:
Human papillomavirus 16*/metabolism
Human papillomavirus 18*/metabolism
Keratinocytes*/metabolism
Keratinocytes*/virology
Papillomavirus E7 Proteins*/genetics
Papillomavirus E7 Proteins*/metabolism
Papillomavirus Infections*/complications
Papillomavirus Infections*/metabolism
Papillomavirus Infections*/therapy
Uterine Cervical Neoplasms*/metabolism
Uterine Cervical Neoplasms*/therapy
Uterine Cervical Neoplasms*/virology
Protein Interaction Maps*
Female ; Humans ; Chromatography, Liquid ; Proteomics ; Tandem Mass Spectrometry ; Molecular Targeted Therapy ; Immunotherapy
Czasopismo naukowe
Tytuł:
Genetic fusion of CCL11 to antigens enhances antigenicity in nucleic acid vaccines and eradicates tumor mass through optimizing T-cell response.
Autorzy:
Qi H; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science, Beijing, China. .; Newish Biological R&D Center, Wuxi, China. .
Sun Z; State Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin, 300071, China.; Newish Biological R&D Center, Wuxi, China.
Gao T; Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Yao Y; Newish Biological R&D Center, Wuxi, China.
Wang Y; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science, Beijing, China.; Newish Biological R&D Center, Wuxi, China.
Li W; Newish Biological R&D Center, Wuxi, China.
Wang X; Newish Biological R&D Center, Wuxi, China.
Wang X; Newish Biological R&D Center, Wuxi, China.
Liu D; Newish Biological R&D Center, Wuxi, China.
Jiang JD; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science, Beijing, China. .
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Źródło:
Molecular cancer [Mol Cancer] 2024 Mar 08; Vol. 23 (1), pp. 46. Date of Electronic Publication: 2024 Mar 08.
Typ publikacji:
Journal Article
MeSH Terms:
Vaccines, DNA*/genetics
Papillomavirus Vaccines*/genetics
Neoplasms*/genetics
Neoplasms*/therapy
Oncogene Proteins, Viral*/genetics
Cancer Vaccines*
Animals ; Mice ; Nucleic Acid-Based Vaccines ; CD8-Positive T-Lymphocytes ; Papillomavirus E7 Proteins/genetics ; Mice, Inbred C57BL ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Development of novel HPV therapeutic vaccine constructs based on engineered exosomes and tumor cell lysates.
Autorzy:
Rezaei F; Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran.
Bolhassani A; Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran. Electronic address: A_.
Sadat SM; Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran.
Arashkia A; Department of Molecular Virology, Pasteur Institute of Iran, Tehran, Iran.
Fotouhi F; Influenza and Respiratory Viruses Department, Pasteur Institute of Iran, Tehran, Iran.
Milani A; Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran; Iranian Comprehensive Hemophilia Care Center, Tehran, Iran.
Pordanjani PM; Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran.
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Źródło:
Life sciences [Life Sci] 2024 Mar 01; Vol. 340, pp. 122456. Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Journal Article
MeSH Terms:
Papillomavirus Vaccines*/genetics
Exosomes*/metabolism
Papillomavirus Infections*/prevention & control
Neoplasms*
Humans ; Animals ; Mice ; Granzymes/metabolism ; HSP27 Heat-Shock Proteins ; Escherichia coli/metabolism ; Papillomavirus E7 Proteins/genetics ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Evaluation of HPV 16 and HPV 18 Oncoprotein Expression as Alternative Diagnostic Tools in Cervical Lesion.
Autorzy:
Sabri NA; Department of Pathology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.; Department of Pathology, Hospital of Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Shamsuddin SH; Department of Pathology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Mat Zin AA; Department of Pathology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.; Department of Pathology, Hospital of Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
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Źródło:
Asian Pacific journal of cancer prevention : APJCP [Asian Pac J Cancer Prev] 2024 Feb 01; Vol. 25 (2), pp. 521-527. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Papillomavirus Infections*
Uterine Cervical Neoplasms*/pathology
Oncogene Proteins, Viral*/genetics
Female ; Humans ; Human papillomavirus 16/genetics ; Human papillomavirus 18/genetics ; Papillomavirus E7 Proteins/genetics
Czasopismo naukowe
Tytuł:
HIV-1 Reverse Transcriptase Expression in HPV16-Infected Epidermoid Carcinoma Cells Alters E6 Expression and Cellular Metabolism, and Induces a Hybrid Epithelial/Mesenchymal Cell Phenotype.
Autorzy:
Zhitkevich A; Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, 119991 Moscow, Russia.
Bayurova E; Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, 119991 Moscow, Russia.; Gamaleya National Research Center for Epidemiology and Microbiology, 123098 Moscow, Russia.
Avdoshina D; Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, 119991 Moscow, Russia.
Zakirova N; Centre for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, 119991 Moscow, Russia.
Frolova G; Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, 119991 Moscow, Russia.
Jansons J; Biomedical Research and Study Centers, LV-1067 Riga, Latvia.; Institute of Microbiology and Virology, Riga Stradins University, LV-1007 Riga, Latvia.
Chowdhury S; Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, CA 94143, USA.
Ivanov A; Gamaleya National Research Center for Epidemiology and Microbiology, 123098 Moscow, Russia.; Centre for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, 119991 Moscow, Russia.
Gordeychuk I; Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, 119991 Moscow, Russia.; Gamaleya National Research Center for Epidemiology and Microbiology, 123098 Moscow, Russia.
Palefsky JM; Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, CA 94143, USA.
Isaguliants M; Institute of Microbiology and Virology, Riga Stradins University, LV-1007 Riga, Latvia.; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 171 77 Stockholm, Sweden.
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Źródło:
Viruses [Viruses] 2024 Jan 26; Vol. 16 (2). Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:
Journal Article
MeSH Terms:
Oncogene Proteins, Viral*/genetics
Oncogene Proteins, Viral*/metabolism
Carcinoma, Squamous Cell*
Uterine Cervical Neoplasms*
HIV Reverse Transcriptase*
Animals ; Mice ; Humans ; Female ; Papillomavirus E7 Proteins/genetics ; Human papillomavirus 16/physiology ; Mice, Nude ; Repressor Proteins/genetics ; Epithelial Cells/metabolism ; Phenotype
Czasopismo naukowe
Tytuł:
A novel HPV16 splicing enhancer critical for viral oncogene expression and cell immortalization.
Autorzy:
Jönsson J; Department of Medical Biochemistry and Microbiology, Uppsala University, BMC-B9, 751 23 Uppsala, Sweden.
Wang L; Department of Medical Biochemistry and Microbiology, Uppsala University, BMC-B9, 751 23 Uppsala, Sweden.; Center of Translational Medicine, Zibo Central Hospital, 255036 Zibo, China.
Kajitani N; Department of Medical Biochemistry and Microbiology, Uppsala University, BMC-B9, 751 23 Uppsala, Sweden.
Schwartz S; Department of Medical Biochemistry and Microbiology, Uppsala University, BMC-B9, 751 23 Uppsala, Sweden.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Jan 11; Vol. 52 (1), pp. 316-336.
Typ publikacji:
Journal Article
MeSH Terms:
Human papillomavirus 16*/genetics
Human papillomavirus 16*/metabolism
Oncogene Proteins, Viral*/genetics
Oncogene Proteins, Viral*/metabolism
Repressor Proteins*/metabolism
Keratinocytes*/virology
Humans ; Papillomavirus E7 Proteins/genetics ; Papillomavirus Infections/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł:
Mapping the landscape of HPV integration and characterising virus and host genome interactions in HPV-positive oropharyngeal squamous cell carcinoma.
Autorzy:
Xu S; Department of Oral and Maxillofacial-Head Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.; National Center for Stomatology, Shanghai, China.; National Clinical Research Center for Oral Diseases, Shanghai, China.; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai, China.
Shi C; Department of Oral and Maxillofacial-Head Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.; National Center for Stomatology, Shanghai, China.; National Clinical Research Center for Oral Diseases, Shanghai, China.; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai, China.
Zhou R; Department of Oral and Maxillofacial-Head Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.; National Center for Stomatology, Shanghai, China.; National Clinical Research Center for Oral Diseases, Shanghai, China.; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai, China.
Han Y; Department of Oral and Maxillofacial-Head Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.; National Center for Stomatology, Shanghai, China.; National Clinical Research Center for Oral Diseases, Shanghai, China.; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai, China.
Li N; Department of Bioinfomatics, Sequanta, Shanghai, China.
Qu C; College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.; National Center for Stomatology, Shanghai, China.; National Clinical Research Center for Oral Diseases, Shanghai, China.; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai, China.; Department of Oral Pathology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, China.
Xia R; College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.; National Center for Stomatology, Shanghai, China.; National Clinical Research Center for Oral Diseases, Shanghai, China.; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai, China.; Department of Oral Pathology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, China.
Zhang C; College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.; National Center for Stomatology, Shanghai, China.; National Clinical Research Center for Oral Diseases, Shanghai, China.; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai, China.; Department of Oral Pathology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, China.
Hu Y; College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.; National Center for Stomatology, Shanghai, China.; National Clinical Research Center for Oral Diseases, Shanghai, China.; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai, China.; Department of Oral Pathology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, China.
Tian Z; College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.; National Center for Stomatology, Shanghai, China.; National Clinical Research Center for Oral Diseases, Shanghai, China.; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai, China.; Department of Oral Pathology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, China.
Liu S; Department of Oral and Maxillofacial-Head Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.; National Center for Stomatology, Shanghai, China.; National Clinical Research Center for Oral Diseases, Shanghai, China.; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai, China.
Wang L; College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.; National Center for Stomatology, Shanghai, China.; National Clinical Research Center for Oral Diseases, Shanghai, China.; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai, China.; Department of Oral Pathology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, China.
Li J; College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.; National Center for Stomatology, Shanghai, China.; National Clinical Research Center for Oral Diseases, Shanghai, China.; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai, China.; Department of Oral Pathology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, China.
Zhang Z; Department of Oral and Maxillofacial-Head Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; College of Stomatology, Shanghai Jiao Tong University, Shanghai, China.; National Center for Stomatology, Shanghai, China.; National Clinical Research Center for Oral Diseases, Shanghai, China.; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Jan; Vol. 14 (1), pp. e1556.
Typ publikacji:
Journal Article
MeSH Terms:
Papillomavirus Infections*/genetics
Head and Neck Neoplasms*
Humans ; Squamous Cell Carcinoma of Head and Neck ; Human Papillomavirus Viruses ; DNA Copy Number Variations ; Papillomaviridae/genetics ; Papillomavirus E7 Proteins/genetics ; Carcinogenesis/genetics
Czasopismo naukowe
Tytuł:
Immunotherapy that leverages HPV-specific immune responses for precancer lesions of cervical cancer.
Autorzy:
Kobayashi O; Department of Obstetrics and Gynecology, Nihon University School of Medicine, Japan.
Taguchi A; Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Japan.
Nakajima T; Department of Obstetrics and Gynecology, Nihon University School of Medicine, Japan.
Ikeda Y; Department of Obstetrics and Gynecology, Nihon University School of Medicine, Japan.
Saito K; Department of Obstetrics and Gynecology, Nihon University School of Medicine, Japan.
Kawana K; Department of Obstetrics and Gynecology, Nihon University School of Medicine, Japan. Electronic address: .
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Źródło:
Taiwanese journal of obstetrics & gynecology [Taiwan J Obstet Gynecol] 2024 Jan; Vol. 63 (1), pp. 22-28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Uterine Cervical Neoplasms*
Papillomavirus Infections*/complications
Papillomavirus Infections*/therapy
Uterine Cervical Dysplasia*
Oncogene Proteins, Viral*
Female ; Humans ; Human Papillomavirus Viruses ; Papillomavirus E7 Proteins ; Papillomaviridae ; Immunotherapy ; Immunity
Czasopismo naukowe
Tytuł:
Impact of HPV strains on molecular mechanisms of cervix cancer.
Autorzy:
Sharma S; Central University of Himachal Pradesh, Dharamshala, Himachal Pradesh, 176215, India. Electronic address: .
Chauhan D; Central University of Himachal Pradesh, Dharamshala, Himachal Pradesh, 176215, India. Electronic address: .
Kumar S; Central University of Himachal Pradesh, Dharamshala, Himachal Pradesh, 176215, India. Electronic address: .
Kumar R; Nagaland University, Lumami, Nagaland, 798627, India. Electronic address: .
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Źródło:
Microbial pathogenesis [Microb Pathog] 2024 Jan; Vol. 186, pp. 106465. Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Uterine Cervical Neoplasms*
Papillomavirus Infections*
Oncogene Proteins, Viral*/genetics
Female ; Humans ; Human Papillomavirus Viruses ; NF-kappa B ; Papillomavirus E7 Proteins ; Transcription Factor AP-1 ; Papillomaviridae/genetics ; Papillomaviridae/metabolism
Czasopismo naukowe
Tytuł:
HPV16 E7 protein antagonizes TNF-α-induced apoptosis of cervical cancer cells via Daxx/JNK pathway.
Autorzy:
Ding S; Institute of Pathogenic Biology, School of Basic Medicine Sciences, Hengyang Medical College, University of South China, Hengyang, China; Department of Clinical Laboratory, The Seventh Affiliated Hospital, University of South China / Hunan Provincial Veterans Administration Hospital, Changsha, China.
Wang H; Institute of Pathogenic Biology, School of Basic Medicine Sciences, Hengyang Medical College, University of South China, Hengyang, China.
Liao Y; Institute of Pathogenic Biology, School of Basic Medicine Sciences, Hengyang Medical College, University of South China, Hengyang, China.
Chen R; Institute of Pathogenic Biology, School of Basic Medicine Sciences, Hengyang Medical College, University of South China, Hengyang, China.
Hu Y; Institute of Pathogenic Biology, School of Basic Medicine Sciences, Hengyang Medical College, University of South China, Hengyang, China.
Wu H; Institute of Pathogenic Biology, School of Basic Medicine Sciences, Hengyang Medical College, University of South China, Hengyang, China.
Shen H; Institute of Pathogenic Biology, School of Basic Medicine Sciences, Hengyang Medical College, University of South China, Hengyang, China.
Tang S; Institute of Pathogenic Biology, School of Basic Medicine Sciences, Hengyang Medical College, University of South China, Hengyang, China. Electronic address: .
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Źródło:
Microbial pathogenesis [Microb Pathog] 2023 Dec; Vol. 185, pp. 106423. Date of Electronic Publication: 2023 Oct 21.
Typ publikacji:
Journal Article
MeSH Terms:
Uterine Cervical Neoplasms*
Oncogene Proteins, Viral*/genetics
Oncogene Proteins, Viral*/metabolism
Papillomavirus Infections*
Female ; Humans ; Human papillomavirus 16/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; MAP Kinase Signaling System ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/metabolism ; Apoptosis
Czasopismo naukowe
Tytuł:
c-MYC-dependent transcriptional inhibition of autophagy is implicated in cisplatin sensitivity in HPV-positive head and neck cancer.
Autorzy:
Medda A; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, IEO Campus, Via Adamello 16, 20139, Milan, Italy.
Compagnoni M; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, IEO Campus, Via Adamello 16, 20139, Milan, Italy.
Spini G; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, IEO Campus, Via Adamello 16, 20139, Milan, Italy.
Citro S; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, IEO Campus, Via Adamello 16, 20139, Milan, Italy.
Croci O; Center for Genomic Science of IIT, (Istituto Italiano di Tecnologia at European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy.
Campaner S; Center for Genomic Science of IIT, (Istituto Italiano di Tecnologia at European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy.
Tagliabue M; Division of Otolaryngology Head & Neck Surgery, IEO, European Institute of Oncology IRCCS, 20141, Milan, Italy.; Department of Biomedical Sciences, University of Sassari, Sassari, Italy.
Ansarin M; Division of Otolaryngology Head & Neck Surgery, IEO, European Institute of Oncology IRCCS, 20141, Milan, Italy.
Chiocca S; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, IEO Campus, Via Adamello 16, 20139, Milan, Italy. .
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Źródło:
Cell death & disease [Cell Death Dis] 2023 Nov 04; Vol. 14 (11), pp. 719. Date of Electronic Publication: 2023 Nov 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Autophagy*
Head and Neck Neoplasms*/drug therapy
Head and Neck Neoplasms*/genetics
Head and Neck Neoplasms*/virology
Papillomavirus Infections*/drug therapy
Papillomavirus Infections*/genetics
Proto-Oncogene Proteins c-myc*/genetics
Proto-Oncogene Proteins c-myc*/metabolism
Humans ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/metabolism
Czasopismo naukowe
Tytuł:
HPV16E1 downregulation altered the cell characteristics involved in cervical cancer development.
Autorzy:
Sasivimolrattana T; Medical Microbiology Interdisciplinary Program, Graduate School, Chulalongkorn University, Bangkok, 10330, Thailand.; Center of Excellence in Applied Medical Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Chaiwongkot A; Center of Excellence in Applied Medical Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.; Division of Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Bhattarakosol P; Center of Excellence in Applied Medical Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand. .; Division of Virology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 25; Vol. 13 (1), pp. 18217. Date of Electronic Publication: 2023 Oct 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oncogene Proteins, Viral*/genetics
Oncogene Proteins, Viral*/metabolism
Uterine Cervical Neoplasms*/metabolism
Papillomavirus Infections*/complications
Papillomavirus Infections*/genetics
Female ; Humans ; Down-Regulation ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/metabolism ; RNA, Small Interfering/genetics ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
HPV 16 E7 alters translesion synthesis signaling.
Autorzy:
Wendel SO; Division of Biology, Kansas State University, Manhattan, KS, 66506, USA.
Stoltz A; Division of Biology, Kansas State University, Manhattan, KS, 66506, USA.
Xu X; Division of Biology, Kansas State University, Manhattan, KS, 66506, USA.
Snow JA; Division of Biology, Kansas State University, Manhattan, KS, 66506, USA.
Wallace N; Division of Biology, Kansas State University, Manhattan, KS, 66506, USA. .
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Źródło:
Virology journal [Virol J] 2022 Oct 20; Vol. 19 (1), pp. 165. Date of Electronic Publication: 2022 Oct 20.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Uterine Cervical Neoplasms*/virology
Papillomavirus E7 Proteins*/genetics
Female ; Humans ; Human papillomavirus 16/genetics ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe

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