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Tytuł :
Recrudescence of a high parasitaemia, severe Plasmodium falciparum malaria episode, treated by artesunate monotherapy.
Autorzy :
Landre S; Service des Maladies Infectieuses et Tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France.
Bienvenu AL; Service Pharmacie, Groupement Hospitalier Nord, Hospices Civils de Lyon, 69004 Lyon, France.
Miailhes P; Service des Maladies Infectieuses et Tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France.
Abraham P; Anesthesiology and Critical Care Medicine, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.
Simon M; Service de Médecine Intensive-Réanimation, Hôpital Edouard Herriot, Hospices Civils de Lyon, 69437 Lyon Cedex 03, France.
Becker A; Service des Maladies Infectieuses et Tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France.
Conrad A; Service des Maladies Infectieuses et Tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France.
Bonnot G; Univ Lyon, Malaria Research Unit, UMR 5246 CNRS-INSA-CPE-University Lyon1, 69100 Villeurbanne, France.
Kouakou YI; Univ Lyon, Malaria Research Unit, UMR 5246 CNRS-INSA-CPE-University Lyon1, 69100 Villeurbanne, France; Institute of Parasitology and Medical Mycology, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France.
Chidiac C; Service des Maladies Infectieuses et Tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France.
Leboucher G; Service Pharmacie, Groupement Hospitalier Nord, Hospices Civils de Lyon, 69004 Lyon, France.
Rimmelé T; Anesthesiology and Critical Care Medicine, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.
Argaud L; Service de Médecine Intensive-Réanimation, Hôpital Edouard Herriot, Hospices Civils de Lyon, 69437 Lyon Cedex 03, France.
Picot S; Univ Lyon, Malaria Research Unit, UMR 5246 CNRS-INSA-CPE-University Lyon1, 69100 Villeurbanne, France; Institute of Parasitology and Medical Mycology, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France. Electronic address: .
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Źródło :
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2021 Apr; Vol. 105, pp. 345-348. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji :
Case Reports
MeSH Terms :
Antimalarials/*therapeutic use
Artesunate/*therapeutic use
Malaria, Falciparum/*drug therapy
Parasitemia/*drug therapy
Aged ; Humans ; Male ; Recurrence
Raport
Tytuł :
Increased malaria parasitaemia among adults living with HIV who have discontinued cotrimoxazole prophylaxis in Kitgum district, Uganda.
Autorzy :
Orishaba P; Clinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.
Kalyango JN; Clinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.; Department of Pharmacy, College of Health Sciences, Makerere University, Kampala, Uganda.
Byakika-Kibwika P; Department of Internal Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Arinaitwe E; Infectious Diseases Research Collaboration, Kampala, Uganda.
Wandera B; Infectious Diseases Research Collaboration, Kampala, Uganda.
Katairo T; Clinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.; Infectious Diseases Research Collaboration, Kampala, Uganda.
Muzeyi W; Clinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.
Nansikombi HT; Clinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.
Nakato A; Clinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.
Mutabazi T; Clinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.
Kamya MR; Department of Internal Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.; Infectious Diseases Research Collaboration, Kampala, Uganda.
Dorsey G; Division of Infectious Diseases, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.
Nankabirwa JI; Clinical Epidemiology Unit, College of Health Sciences, Makerere University, Kampala, Uganda.; Infectious Diseases Research Collaboration, Kampala, Uganda.
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Źródło :
PloS one [PLoS One] 2020 Nov 11; Vol. 15 (11), pp. e0240838. Date of Electronic Publication: 2020 Nov 11 (Print Publication: 2020).
Typ publikacji :
Journal Article; Observational Study; Research Support, N.I.H., Extramural
MeSH Terms :
Antimalarials/*therapeutic use
HIV Infections/*immunology
Malaria/*epidemiology
Parasitemia/*epidemiology
Trimethoprim, Sulfamethoxazole Drug Combination/*therapeutic use
Adult ; Cross-Sectional Studies ; Female ; HIV Infections/complications ; Humans ; Malaria/immunology ; Malaria/parasitology ; Malaria/prevention & control ; Male ; Middle Aged ; Parasitemia/immunology ; Parasitemia/parasitology ; Parasitemia/prevention & control ; Plasmodium/immunology ; Plasmodium/isolation & purification ; Prevalence ; Uganda/epidemiology
Czasopismo naukowe
Tytuł :
Intervention of standardized ethanol leaf extract of Annickia polycarpa, (DC.) Setten and Maas ex I.M. Turner. (Annonaceae), in Plasmodium berghei infested mice produced anti-malaria action and normalized gross hematological indices.
Autorzy :
Kumatia EK; Phytochemistry Department, Centre for Plant Medicine Research, Mampong-Akwapim, Ghana. Electronic address: .
Ayertey F; Phytochemistry Department, Centre for Plant Medicine Research, Mampong-Akwapim, Ghana.
Appiah-Opong R; Chemical Pathology Department, Noguchi Memorial Institute for Medical Research, Legon, Accra, Ghana.
Bagyour GK; Chemistry and Applied Biochemistry Department, University of Development Studies, Navrongo-Campus, Tamale, Ghana.
Asare KO; Clinical Resaerch Department, Centre for Plant Medicine Research, Mampong-Akwapim, Ghana.
Mbatcho VC; Chemistry and Applied Biochemistry Department, University of Development Studies, Navrongo-Campus, Tamale, Ghana.
Dabo J; Biodiversity Conservation and Ecoservices Division, Forestry Research Institute of Ghana, Kumasi, Ghana.
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113449. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji :
Journal Article
MeSH Terms :
Annonaceae*/chemistry
Plant Leaves*/chemistry
Antimalarials/*pharmacology
Malaria/*drug therapy
Plant Extracts/*pharmacology
Plasmodium berghei/*drug effects
Anemia/blood ; Anemia/drug therapy ; Anemia/parasitology ; Animals ; Antimalarials/isolation & purification ; Aporphines/pharmacology ; Disease Models, Animal ; Ethanol/chemistry ; Female ; Leukopenia/blood ; Leukopenia/drug therapy ; Leukopenia/parasitology ; Malaria/blood ; Malaria/parasitology ; Mice, Inbred ICR ; Parasite Load ; Parasitemia/blood ; Parasitemia/drug therapy ; Parasitemia/parasitology ; Plant Extracts/isolation & purification ; Plasmodium berghei/growth & development ; Polycythemia/blood ; Polycythemia/drug therapy ; Polycythemia/parasitology ; Solvents/chemistry ; Thrombocytopenia/blood ; Thrombocytopenia/drug therapy ; Thrombocytopenia/parasitology
Czasopismo naukowe
Tytuł :
Antrocaryon micraster (A. Chev. And Guillaumin) stem bark extract demonstrated anti-malaria action and normalized hematological indices in Plasmodium berghei infested mice in the Rane's test.
Autorzy :
Kumatia EK; Department of Phytochemistry, Centre for Plant Medicine Research, Mampong-Akwapim, Ghana. Electronic address: .
Ayertey F; Department of Phytochemistry, Centre for Plant Medicine Research, Mampong-Akwapim, Ghana.
Appiah-Opong R; Department of Chemical Pathology, Noguchi Memorial Institute for Medical Research, Legon, Accra, Ghana.
Bolah P; Department of Phytochemistry, Centre for Plant Medicine Research, Mampong-Akwapim, Ghana.
Ehun E; Department of Phytochemistry, Centre for Plant Medicine Research, Mampong-Akwapim, Ghana.
Dabo J; Division of Biodiversity Conservation and Ecoservices, Forestry Research Institute of Ghana, Kumasi, Ghana.
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Feb 10; Vol. 266, pp. 113427. Date of Electronic Publication: 2020 Oct 03.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Anacardiaceae/*chemistry
Antimalarials/*pharmacology
Malaria/*drug therapy
Plant Extracts/*pharmacology
Plasmodium berghei/*drug effects
Animals ; Antimalarials/administration & dosage ; Dose-Response Relationship, Drug ; Female ; Ghana ; Malaria/parasitology ; Medicine, African Traditional ; Mice ; Mice, Inbred ICR ; Parasitemia/drug therapy ; Parasitemia/parasitology ; Plant Bark ; Plant Extracts/administration & dosage
Czasopismo naukowe
Tytuł :
In vitro and in vivo antiplasmodial activity of hydroethanolic bark extract of Bridelia atroviridis müll. Arg. (Euphorbiaceae) and lc-ms-based phytochemical analysis.
Autorzy :
Djouwoug CN; Laboratory of Animal Physiology, Faculty of Science, University of Yaoundé I, Cameroon.
Gounoue RK; Laboratory of Animal Physiology, Faculty of Science, University of Yaoundé I, Cameroon.
Ngueguim FT; Laboratory of Animal Physiology, Faculty of Science, University of Yaoundé I, Cameroon.
NankapTsakem JM; Laboratory of Animal Physiology, Faculty of Science, University of Yaoundé I, Cameroon.
Gouni CD; Laboratory of Natural Substances, Faculty of Science, University of Yaoundé I, Cameroon.
Kandeda AC; Laboratory of Animal Physiology, Faculty of Science, University of Yaoundé I, Cameroon.
Ngouela S; Laboratory of Natural Substances, Faculty of Science, University of Yaoundé I, Cameroon.
Lenta BN; Laboratory of Natural Substances, High Teaching Training College, University of Yaounde I, Cameroon.
Sewald N; Laboratory of Organic and Bioorganic Chemistry, University of Bielefeld, Germany.
Fekam FB; Laboratory for Phytobiochemistry and Medicinal Plants Studies, Antimicrobial and Biocontrol Agents Unit, Faculty of Science, University of Yaounde I, Cameroon.
Dimo T; Laboratory of Animal Physiology, Faculty of Science, University of Yaoundé I, Cameroon. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Feb 10; Vol. 266, pp. 113424. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Antimalarials/*pharmacology
Euphorbiaceae/*chemistry
Plant Extracts/*pharmacology
Plasmodium berghei/*drug effects
Plasmodium falciparum/*drug effects
Animals ; Antimalarials/administration & dosage ; Antimalarials/isolation & purification ; Chlorocebus aethiops ; Chloroquine/pharmacology ; Chromatography, High Pressure Liquid ; Dose-Response Relationship, Drug ; Female ; Inhibitory Concentration 50 ; Malaria/drug therapy ; Malaria/parasitology ; Male ; Mass Spectrometry ; Parasitemia/drug therapy ; Parasitemia/parasitology ; Plant Extracts/administration & dosage ; Plant Extracts/chemistry ; Rats ; Rats, Wistar ; Vero Cells
Czasopismo naukowe
Tytuł :
IL-4 Treatment Mitigates Experimental Cerebral Malaria by Reducing Parasitemia, Dampening Inflammation, and Lessening the Cytotoxicity of T Cells.
Autorzy :
Wu X; Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA 17033; and.
Thylur RP; Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA 17033; and.
Dayanand KK; Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA 17033; and.
Punnath K; Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA 17033; and.
Norbury CC; Department of Microbiology and Immunology, The Pennsylvania State University College of Medicine, Hershey, PA 17033.
Gowda DC; Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA 17033; and .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Jan 01; Vol. 206 (1), pp. 118-131. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms :
Antimalarials/*therapeutic use
Brain/*pathology
Interleukin-4/*therapeutic use
Malaria, Cerebral/*immunology
Plasmodium falciparum/*physiology
T-Lymphocytes, Cytotoxic/*immunology
Animals ; Cytotoxicity, Immunologic ; Humans ; Inflammation ; Malaria, Cerebral/therapy ; Mice ; Mice, Inbred C57BL ; Models, Animal ; Parasitemia ; Signal Transduction
Czasopismo naukowe
Tytuł :
Therapeutic Efficacy of Artemether-Lumefantrine for Uncomplicated Falciparum Malaria in Northern Zambia.
Autorzy :
Ippolito MM; The Johns Hopkins Malaria Research Institute, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.; Division of Clinical Pharmacology, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Pringle JC; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.
Siame M; Ministry of Health, Government of the Republic of Zambia, Lusaka, Zambia.
Katowa B; Macha Research Trust, Macha, Zambia.
Aydemir O; Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island.
Oluoch PO; Center for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.; Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island.
Huang L; Department of Clinical Pharmacology, University of California San Francisco School of Pharmacy, San Francisco, California.
Aweeka FT; Department of Clinical Pharmacology, University of California San Francisco School of Pharmacy, San Francisco, California.
Bailey JA; Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island.
Juliano JJ; Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Meshnick SR; Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina.
Shapiro TA; The Johns Hopkins Malaria Research Institute, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.; Division of Clinical Pharmacology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Moss WJ; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.; The Johns Hopkins Malaria Research Institute, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.
Thuma PE; Macha Research Trust, Macha, Zambia.; The Johns Hopkins Malaria Research Institute, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.
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Źródło :
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2020 Dec; Vol. 103 (6), pp. 2224-2232. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimalarials/*pharmacology
Artemether, Lumefantrine Drug Combination/*pharmacology
Malaria, Falciparum/*drug therapy
Plasmodium falciparum/*drug effects
Child, Preschool ; Drug Resistance ; Female ; Humans ; Infant ; Malaria, Falciparum/epidemiology ; Malaria, Falciparum/parasitology ; Male ; Parasitemia/drug therapy ; Parasitemia/parasitology ; Zambia/epidemiology
Czasopismo naukowe
Tytuł :
The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network.
Autorzy :
Hossain MS; WorldWide Antimalarial Resistance Network (WWARN), Oxford, United Kingdom.; Global Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; International Centre for Diarrheal Diseases and Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Commons RJ; WorldWide Antimalarial Resistance Network (WWARN), Oxford, United Kingdom.; Global Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia.; Internal Medical Services, Ballarat Health Services, Ballarat, Victoria, Australia.
Douglas NM; Global Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.
Thriemer K; Global Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia.
Alemayehu BH; ICAP at Mailman School of Public Health, Columbia University, New York, New York, United States of America.
Amaratunga C; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America.
Anvikar AR; National Institute of Malaria Research, Dwarka, New Delhi, India.
Ashley EA; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao PDR.
Asih PBS; Eijkman Institute for Molecular Biology, Jakarta, Indonesia.
Carrara VI; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.
Lon C; Department of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok, Thailand.; Armed Forces Research Institute of Medical Sciences, Phnom Penh, Cambodia.
D'Alessandro U; Medical Research Council Unit The Gambia at LSTMH, Fajara, The Gambia.
Davis TME; Medical School, University of Western Australia, Fremantle Hospital, Fremantle, Australia.
Dondorp AM; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Edstein MD; Australian Defence Force Malaria and Infectious Disease Institute, Enoggera, Brisbane, Australia.
Fairhurst RM; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America.
Ferreira MU; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Hwang J; US President's Malaria Initiative, Malaria Branch, US Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.; Global Health Group, University of California San Francisco, San Francisco, California, United States of America.
Janssens B; Médecins Sans Frontieres, Brussels, Belgium.
Karunajeewa H; Melbourne Medical School-Western Health, The University of Melbourne, Melbourne, Australia.; Western Health Chronic Disease Alliance, Sunshine Hospital, St Albans, Melbourne, Australia.
Kiechel JR; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.
Ladeia-Andrade S; Laboratory of Parasitic Diseases, Oswaldo Cruz Institute/Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.; Amazonian Malaria Initiative/Amazon Network for the Surveillance of Antimalarial Drug Resistance, Ministry of Health of Brazil, Cruzeiro do Sul, Brazil.
Laman M; Medical School, University of Western Australia, Fremantle Hospital, Fremantle, Australia.; Papua New Guinea Institute of Medical Research, Madang, Papua New Guinea.
Mayxay M; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao PDR.; Institute of Research and Education Development (IRED), University of Health Sciences, Ministry of Health, Vientiane, Lao PDR.
McGready R; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.
Moore BR; Medical School, University of Western Australia, Fremantle Hospital, Fremantle, Australia.; School of Pharmacy and Biomedical Sciences, Curtin University, Perth, Australia.
Mueller I; Division of Population Health and Immunity, The Walter & Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.; Parasites and Insect Vectors Department, Institut Pasteur, Paris, France.
Newton PN; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao PDR.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Thuy-Nhien NT; Oxford University Clinical Research Unit (OUCRU), Ho Chi Minh City, Vietnam.
Noedl H; MARIB-Malaria Research Initiative Bandarban, Vienna, Austria.
Nosten F; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.
Phyo AP; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.; Myanmar Oxford Clinical Research Unit, Yangon, Myanmar.
Poespoprodjo JR; Mimika District Hospital, Timika, Indonesia.; Timika Malaria Research Programme, Papuan Health and Community Development Foundation, Timika, Indonesia.; Paediatric Research Office, Department of Child Health, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.
Saunders DL; Division of Medicine, United States Army Research Institute of Infectious Diseases, Ft. Detrick, Maryland, United States of America.
Smithuis F; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Myanmar Oxford Clinical Research Unit, Yangon, Myanmar.; Medical Action Myanmar, Yangon, Myanmar.
Spring MD; Department of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok, Thailand.
Stepniewska K; WorldWide Antimalarial Resistance Network (WWARN), Oxford, United Kingdom.; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
Suon S; National Center for Parasitology, Entomology, and Malaria Control, Phnom Penh, Cambodia.
Suputtamongkol Y; Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Syafruddin D; Eijkman Institute for Molecular Biology, Jakarta, Indonesia.; Department of Parasitology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Tran HT; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Oxford University Clinical Research Unit (OUCRU), Ho Chi Minh City, Vietnam.
Valecha N; National Institute of Malaria Research, Dwarka, New Delhi, India.
Van Herp M; Médecins Sans Frontieres, Brussels, Belgium.
Van Vugt M; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Academic Medical Centre, Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands.
White NJ; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Guerin PJ; WorldWide Antimalarial Resistance Network (WWARN), Oxford, United Kingdom.; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
Simpson JA; WorldWide Antimalarial Resistance Network (WWARN), Oxford, United Kingdom.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.
Price RN; WorldWide Antimalarial Resistance Network (WWARN), Oxford, United Kingdom.; Global Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia.; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
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Źródło :
PLoS medicine [PLoS Med] 2020 Nov 19; Vol. 17 (11), pp. e1003393. Date of Electronic Publication: 2020 Nov 19 (Print Publication: 2020).
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimalarials/*therapeutic use
Artemether, Lumefantrine Drug Combination/*therapeutic use
Malaria, Vivax/*drug therapy
Plasmodium vivax/*pathogenicity
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Artemisinins/therapeutic use ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Malaria/drug therapy ; Malaria, Falciparum/drug therapy ; Male ; Middle Aged ; Parasitemia/drug therapy ; Plasmodium vivax/drug effects ; Young Adult
Czasopismo naukowe
Tytuł :
Liver Function Test Abnormalities in Experimental and Clinical Plasmodium vivax Infection.
Autorzy :
Odedra A; QIMR Berghofer Medical Research Institute, Brisbane, Australia.; Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Webb L; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Marquart L; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Britton LJ; School of Medicine, The University of Queensland, Brisbane, Australia.; Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Australia.
Chalon S; Medicines for Malaria Venture, Geneva, Switzerland.
Moehrle JJ; Medicines for Malaria Venture, Geneva, Switzerland.
Anstey NM; Global and Tropical Health Division, Menzies School of Health Research, Darwin, Australia.
William T; Gleneagles Hospital, Kota Kinabalu, Malaysia.; Clinical Research Centre, Queen Elizabeth Hospital, Kota Kinabalu, Malaysia.
Grigg MJ; Global and Tropical Health Division, Menzies School of Health Research, Darwin, Australia.
Lalloo DG; Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Barber BE; Global and Tropical Health Division, Menzies School of Health Research, Darwin, Australia.; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
McCarthy JS; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
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Źródło :
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2020 Nov; Vol. 103 (5), pp. 1910-1917.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adamantane/*analogs & derivatives
Alanine Transaminase/*blood
Antimalarials/*therapeutic use
Liver Diseases/*drug therapy
Malaria, Vivax/*drug therapy
Peroxides/*therapeutic use
Plasmodium vivax/*isolation & purification
Adamantane/therapeutic use ; Adult ; Artemisinins/therapeutic use ; Chloroquine/therapeutic use ; Cohort Studies ; Female ; Humans ; Liver Diseases/blood ; Liver Diseases/parasitology ; Liver Function Tests ; Malaria, Vivax/blood ; Malaria, Vivax/parasitology ; Malaysia ; Male ; Parasitemia/drug therapy ; Thailand ; Young Adult
Czasopismo naukowe
Tytuł :
The efficacy of intermittent preventive therapy in the eradication of peripheral and placental parasitemia in a malaria-endemic environment, as seen in a tertiary hospital in Abuja, Nigeria.
Autorzy :
Umemmuo MU; Department of Obstetrics and Gynecology, National Hospital, Abuja, Nigeria.
Agboghoroma CO; Department of Obstetrics and Gynecology, National Hospital, Abuja, Nigeria.
Iregbu KC; Department of Microbiology, National Hospital, Abuja, Nigeria.
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Źródło :
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics [Int J Gynaecol Obstet] 2020 Mar; Vol. 148 (3), pp. 338-343. Date of Electronic Publication: 2020 Jan 17.
Typ publikacji :
Journal Article
MeSH Terms :
Antimalarials/*therapeutic use
Malaria/*prevention & control
Parasitemia/*prevention & control
Placenta/*microbiology
Pregnancy Complications, Parasitic/*prevention & control
Pyrimethamine/*therapeutic use
Sulfadoxine/*therapeutic use
Adolescent ; Adult ; Birth Weight ; Cross-Sectional Studies ; Drug Combinations ; Female ; Humans ; Infant, Newborn ; Nigeria/epidemiology ; Parasitemia/epidemiology ; Pregnancy ; Pregnancy Complications, Parasitic/epidemiology ; Prevalence ; Tertiary Care Centers
Czasopismo naukowe
Tytuł :
The extended recovery ring-stage survival assay provides a superior association with patient clearance half-life and increases throughput.
Autorzy :
Davis SZ; Eck Institute for Global Health, Dept. of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.; Molecular, Cell, and Systems Biology Department, University of California Riverside, Riverside, CA, USA.
Singh PP; Eck Institute for Global Health, Dept. of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Vendrely KM; Eck Institute for Global Health, Dept. of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Shoue DA; Eck Institute for Global Health, Dept. of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Checkley LA; Eck Institute for Global Health, Dept. of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
McDew-White M; Texas Biomedical Research Institute, San Antonio, TX, USA.
Button-Simons KA; Eck Institute for Global Health, Dept. of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Cassady Z; Eck Institute for Global Health, Dept. of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Sievert MAC; Eck Institute for Global Health, Dept. of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Foster GJ; Eck Institute for Global Health, Dept. of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.
Nosten FH; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Mae Sot, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine Research Building, University of Oxford Old Road Campus, Oxford, UK.
Anderson TJC; Texas Biomedical Research Institute, San Antonio, TX, USA.
Ferdig MT; Eck Institute for Global Health, Dept. of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA. .
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Źródło :
Malaria journal [Malar J] 2020 Jan 31; Vol. 19 (1), pp. 54. Date of Electronic Publication: 2020 Jan 31.
Typ publikacji :
Journal Article
MeSH Terms :
Antimalarials/*pharmacology
Artemisinins/*pharmacology
Malaria, Falciparum/*diagnosis
Parasitemia/*diagnosis
Plasmodium falciparum/*isolation & purification
Drug Resistance ; Erythrocytes/parasitology ; Flow Cytometry ; Fluorescent Dyes ; Half-Life ; Humans ; Malaria, Falciparum/drug therapy ; Organic Chemicals ; Parasitemia/drug therapy ; Plasmodium falciparum/drug effects ; Povidone ; Real-Time Polymerase Chain Reaction/methods ; Silicon Dioxide
Czasopismo naukowe
Tytuł :
In Vivo Antimalarial Activity of Crude Fruit Extract of Capsicum frutescens Var. Minima (Solanaceae) against Plasmodium berghei -Infected Mice.
Autorzy :
Habte G; Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia.; Department of Pharmacy, College of Health Sciences, Mettu University, P.O. Box 318, Mettu, Ethiopia.
Assefa S; Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia.
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Źródło :
BioMed research international [Biomed Res Int] 2020 Aug 25; Vol. 2020, pp. 1320952. Date of Electronic Publication: 2020 Aug 25 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Antimalarials/*pharmacology
Capsicum/*chemistry
Malaria/*drug therapy
Plant Extracts/*pharmacology
Animals ; Antimalarials/chemistry ; Antimalarials/toxicity ; Body Temperature/drug effects ; Body Weight/drug effects ; Fruit/chemistry ; Hematocrit ; Malaria/mortality ; Malaria/parasitology ; Male ; Mice ; Parasitemia/drug therapy ; Parasitemia/parasitology ; Phytochemicals/analysis ; Plant Extracts/chemistry ; Plant Extracts/toxicity ; Plasmodium berghei/pathogenicity ; Toxicity Tests, Acute
Czasopismo naukowe
Tytuł :
A Single-Dose Combination Study with the Experimental Antimalarials Artefenomel and DSM265 To Determine Safety and Antimalarial Activity against Blood-Stage Plasmodium falciparum in Healthy Volunteers.
Autorzy :
McCarthy JS; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Q-Pharm, Pty., Ltd., Brisbane, Queensland, Australia.; The University of Queensland, Brisbane, Queensland, Australia.
Rückle T; Medicines for Malaria Venture, Meyrin, Switzerland.
Elliott SL; Q-Pharm, Pty., Ltd., Brisbane, Queensland, Australia.
Ballard E; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Collins KA; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Marquart L; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Griffin P; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Q-Pharm, Pty., Ltd., Brisbane, Queensland, Australia.; Department of Medicine and Infectious Diseases, Mater Hospital and Mater Research, Raymond Terrace, South Brisbane, Queensland, Australia.; The University of Queensland, Brisbane, Queensland, Australia.
Chalon S; Medicines for Malaria Venture, Meyrin, Switzerland.
Möhrle JJ; Medicines for Malaria Venture, Meyrin, Switzerland .
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2019 Dec 20; Vol. 64 (1). Date of Electronic Publication: 2019 Dec 20 (Print Publication: 2019).
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adamantane/*analogs & derivatives
Antimalarials/*administration & dosage
Malaria, Falciparum/*drug therapy
Parasitemia/*drug therapy
Peroxides/*administration & dosage
Pyrimidines/*administration & dosage
Triazoles/*administration & dosage
Adamantane/administration & dosage ; Adamantane/pharmacokinetics ; Administration, Oral ; Adult ; Antimalarials/pharmacokinetics ; Drug Combinations ; Female ; Healthy Volunteers ; Humans ; Malaria, Falciparum/metabolism ; Malaria, Falciparum/parasitology ; Male ; Middle Aged ; Parasitemia/metabolism ; Parasitemia/parasitology ; Peroxides/pharmacokinetics ; Plasmodium falciparum/drug effects ; Pyrimidines/pharmacokinetics ; Triazoles/pharmacokinetics ; Young Adult
Czasopismo naukowe
Tytuł :
Tafenoquine for preventing relapse in people with Plasmodium vivax malaria.
Autorzy :
Rodrigo C; Department of Pathology, School of Medical Sciences, University of New South Wales, Sydney, Australia.
Rajapakse S; Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Fernando D; Department of Parasitology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
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Źródło :
The Cochrane database of systematic reviews [Cochrane Database Syst Rev] 2020 Sep 06; Vol. 9. Cochrane AN: CD010458. Date of Electronic Publication: 2020 Sep 06.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms :
Secondary Prevention*
Aminoquinolines/*administration & dosage
Antimalarials/*administration & dosage
Malaria, Vivax/*drug therapy
Primaquine/*administration & dosage
Adult ; Aminoquinolines/adverse effects ; Antimalarials/adverse effects ; Chloroquine/administration & dosage ; Chloroquine/adverse effects ; Drug Administration Schedule ; Glucosephosphate Dehydrogenase Deficiency/complications ; Humans ; Parasitemia/drug therapy ; Placebos ; Primaquine/adverse effects ; Randomized Controlled Trials as Topic ; Recurrence
Czasopismo naukowe
Tytuł :
Safety, Pharmacokinetics, and Activity of High-Dose Ivermectin and Chloroquine against the Liver Stage of Plasmodium cynomolgi Infection in Rhesus Macaques.
Autorzy :
Vanachayangkul P; Department of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Im-Erbsin R; Department of Veterinary Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Tungtaeng A; Department of Veterinary Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Kodchakorn C; Department of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Roth A; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Center for Global Health and Infectious Diseases Research, College of Public Health, University of South Florida, Tampa, Florida, USA.
Adams J; Center for Global Health and Infectious Diseases Research, College of Public Health, University of South Florida, Tampa, Florida, USA.
Chaisatit C; Department of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Saingam P; Department of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Sciotti RJ; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Reichard GA; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Nolan CK; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Pybus BS; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Black CC; Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Lugo-Roman LA; Department of Veterinary Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Wegner MD; Department of Veterinary Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Smith PL; Department of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Wojnarski M; Department of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Vesely BA; Department of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Kobylinski KC; Department of Entomology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand .
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2020 Aug 20; Vol. 64 (9). Date of Electronic Publication: 2020 Aug 20 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimalarials/*pharmacology
Chloroquine/*pharmacology
Ivermectin/*pharmacology
Liver/*drug effects
Malaria/*drug therapy
Plasmodium cynomolgi/*drug effects
Animals ; Antimalarials/blood ; Antimalarials/pharmacokinetics ; Biological Availability ; Chloroquine/blood ; Chloroquine/pharmacokinetics ; Drug Administration Schedule ; Drug Combinations ; Drug Synergism ; Female ; Hepatocytes/drug effects ; Hepatocytes/parasitology ; Ivermectin/blood ; Ivermectin/pharmacokinetics ; Liver/parasitology ; Macaca mulatta ; Malaria/parasitology ; Male ; Parasitemia/drug therapy ; Plasmodium cynomolgi/growth & development ; Plasmodium cynomolgi/pathogenicity ; Primary Cell Culture ; Schizonts/drug effects ; Schizonts/growth & development
Czasopismo naukowe
Tytuł :
Assessment of molecular markers of anti-malarial drug resistance among children participating in a therapeutic efficacy study in western Kenya.
Autorzy :
Chebore W; Kenya Medical Research Institute, Centre for Global Health Research, P.O. Box 1578, Kisumu, Kenya.; Maseno University, Kisumu, Kenya.
Zhou Z; Centers for Disease Control and Prevention, Malaria Branch, Atlanta, GA, USA.
Westercamp N; Centers for Disease Control and Prevention, Malaria Branch, Atlanta, GA, USA.
Otieno K; Kenya Medical Research Institute, Centre for Global Health Research, P.O. Box 1578, Kisumu, Kenya.
Shi YP; Centers for Disease Control and Prevention, Malaria Branch, Atlanta, GA, USA.
Sergent SB; Centers for Disease Control and Prevention, Malaria Branch, Atlanta, GA, USA.
Rondini KA; Centers for Disease Control and Prevention, Malaria Branch, Atlanta, GA, USA.; Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Svigel SS; Centers for Disease Control and Prevention, Malaria Branch, Atlanta, GA, USA.
Guyah B; Maseno University, Kisumu, Kenya.
Udhayakumar V; Centers for Disease Control and Prevention, Malaria Branch, Atlanta, GA, USA.
Halsey ES; Centers for Disease Control and Prevention, Malaria Branch, Atlanta, GA, USA.; U.S. President's Malaria Initiative, Atlanta, GA, USA.
Samuels AM; Centers for Disease Control and Prevention, Malaria Branch, Atlanta, GA, USA.; Centers for Disease Control and Prevention, Kisumu, Kenya.
Kariuki S; Kenya Medical Research Institute, Centre for Global Health Research, P.O. Box 1578, Kisumu, Kenya. .
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Źródło :
Malaria journal [Malar J] 2020 Aug 14; Vol. 19 (1), pp. 291. Date of Electronic Publication: 2020 Aug 14.
Typ publikacji :
Journal Article
MeSH Terms :
Antimalarials/*therapeutic use
Drug Resistance/*genetics
Malaria, Falciparum/*epidemiology
Plasmodium falciparum/*drug effects
Protozoan Proteins/*blood
Biomarkers/blood ; Child, Preschool ; Genes, Protozoan ; Humans ; Infant ; Kenya/epidemiology ; Malaria, Falciparum/blood ; Malaria, Falciparum/parasitology ; Parasitemia/drug therapy ; Plasmodium falciparum/genetics ; Prevalence
Czasopismo naukowe
Tytuł :
Speed of action and stage specificity of Bencha-loga-wichian, a Thai traditional antipyretic formulation, against Plasmodium falciparum and the chloroquine-potentiating activity of its active compounds, tiliacorinine and yanangcorinine.
Autorzy :
Nutmakul T; Department of Pharmaceutical Botany, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayuthaya Road, Bangkok, 10400, Thailand. Electronic address: .
Pattanapanyasat K; Office for Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok, 10700, Thailand. Electronic address: .
Soonthornchareonnon N; Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayuthaya Road, Bangkok, 10400, Thailand. Electronic address: .
Shiomi K; Laboratory of Biological Functions, Kitasato Institute for Life Sciences, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan. Electronic address: .
Mori M; Laboratory of Biological Functions, Kitasato Institute for Life Sciences, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan. Electronic address: .
Prathanturarug S; Department of Pharmaceutical Botany, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayuthaya Road, Bangkok, 10400, Thailand. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2020 Aug 10; Vol. 258, pp. 112909. Date of Electronic Publication: 2020 Apr 30.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Antimalarials/*pharmacology
Benzylisoquinolines/*pharmacology
Plant Extracts/*pharmacology
Antimalarials/administration & dosage ; Antimalarials/isolation & purification ; Antipyretics/administration & dosage ; Antipyretics/pharmacology ; Benzylisoquinolines/administration & dosage ; Benzylisoquinolines/isolation & purification ; Chloroquine/administration & dosage ; Chloroquine/pharmacology ; Drug Resistance ; Drug Synergism ; Drug Therapy, Combination ; Medicine, East Asian Traditional ; Parasitemia/drug therapy ; Plant Extracts/administration & dosage ; Plasmodium falciparum/drug effects ; Thailand ; Time Factors
Czasopismo naukowe
Tytuł :
Nanoemulsion composed of 10-(4,5-dihydrothiazol-2-yl)thio)decan-1-ol), a synthetic analog of 3-alkylpiridine marine alkaloid: development, characterization, and antimalarial activity.
Autorzy :
Silva MGD; Federal University of São João del-Rei, Campus Centro Oeste Dona Lindu, Sebastião Gonçalves Coelho 400, Chanadour, 35.501-296, Divinópolis, Minas Gerais, Brazil.
Cardoso JF; School of Pharmacy, Federal University of Ouro Preto, Campus Morro do Cruzeiro w/n, Bauxita, 35.400-000, Ouro Preto, Minas Gerais, Brazil.
Perasoli FB; School of Pharmacy, Federal University of Ouro Preto, Campus Morro do Cruzeiro w/n, Bauxita, 35.400-000, Ouro Preto, Minas Gerais, Brazil.
Branquinho RT; School of Pharmacy, Federal University of Ouro Preto, Campus Morro do Cruzeiro w/n, Bauxita, 35.400-000, Ouro Preto, Minas Gerais, Brazil.
Mourão RS; School of Pharmacy, Federal University of Ouro Preto, Campus Morro do Cruzeiro w/n, Bauxita, 35.400-000, Ouro Preto, Minas Gerais, Brazil.
Tavares HDS; Federal University of São João del-Rei, Campus Centro Oeste Dona Lindu, Sebastião Gonçalves Coelho 400, Chanadour, 35.501-296, Divinópolis, Minas Gerais, Brazil.
Xocaira MLCT; Federal University of São João del-Rei, Campus Centro Oeste Dona Lindu, Sebastião Gonçalves Coelho 400, Chanadour, 35.501-296, Divinópolis, Minas Gerais, Brazil.
Guimarães DSM; Federal University of São João del-Rei, Campus Centro Oeste Dona Lindu, Sebastião Gonçalves Coelho 400, Chanadour, 35.501-296, Divinópolis, Minas Gerais, Brazil.
Viana GHR; Federal University of São João del-Rei, Campus Centro Oeste Dona Lindu, Sebastião Gonçalves Coelho 400, Chanadour, 35.501-296, Divinópolis, Minas Gerais, Brazil.
Varotti FP; Federal University of São João del-Rei, Campus Centro Oeste Dona Lindu, Sebastião Gonçalves Coelho 400, Chanadour, 35.501-296, Divinópolis, Minas Gerais, Brazil.
Silva GRD; School of Pharmacy, Federal University of Ouro Preto, Campus Morro do Cruzeiro w/n, Bauxita, 35.400-000, Ouro Preto, Minas Gerais, Brazil. Electronic address: .
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Źródło :
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2020 Aug 01; Vol. 151, pp. 105382. Date of Electronic Publication: 2020 May 26.
Typ publikacji :
Journal Article
MeSH Terms :
Alkaloids*/pharmacology
Antimalarials*/pharmacology
Antimalarials*/therapeutic use
Malaria*/drug therapy
Animals ; Parasitemia/drug therapy ; Plasmodium berghei ; Plasmodium falciparum
Czasopismo naukowe
Tytuł :
Liver Enzyme Elevations in Plasmodium falciparum Volunteer Infection Studies: Findings and Recommendations.
Autorzy :
Chughlay MF; Medicines for Malaria Venture, Geneva, Switzerland.
Akakpo S; Medicines for Malaria Venture, Geneva, Switzerland.
Odedra A; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Csermak-Renner K; Novartis Pharma AG, Basel, Switzerland.
Djeriou E; Sanofi, Gentilly, France.
Winnips C; Novartis Pharma AG, Basel, Switzerland.
Leboulleux D; Sanofi, Gentilly, France.
Gaur AH; St. Jude Children's Research Hospital, Memphis, Tennessee.
Shanks GD; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
McCarthy J; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Chalon S; Medicines for Malaria Venture, Geneva, Switzerland.
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Źródło :
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2020 Jul; Vol. 103 (1), pp. 378-393. Date of Electronic Publication: 2020 Apr 16.
Typ publikacji :
Journal Article
MeSH Terms :
Healthy Volunteers*
Alanine Transaminase/*metabolism
Antimalarials/*adverse effects
Aspartate Aminotransferases/*metabolism
Chemical and Drug Induced Liver Injury/*epidemiology
Malaria, Falciparum/*drug therapy
Parasitemia/*drug therapy
Acrylamides/adverse effects ; Adamantane/adverse effects ; Adamantane/analogs & derivatives ; Adult ; Aminopyridines/adverse effects ; Aminoquinolines/adverse effects ; Chemical and Drug Induced Liver Injury/etiology ; Chemical and Drug Induced Liver Injury/metabolism ; Erythrocyte Transfusion ; Erythrocytes/parasitology ; Female ; Ferrous Compounds/adverse effects ; Heterocyclic Compounds, 4 or More Rings/adverse effects ; Humans ; Indoles/adverse effects ; Isoquinolines/adverse effects ; Male ; Metallocenes/adverse effects ; Peroxides/adverse effects ; Piperazines/adverse effects ; Plasmodium falciparum ; Primaquine/adverse effects ; Pyrimidines/adverse effects ; Quinolines/adverse effects ; Spiro Compounds/adverse effects ; Sulfones/adverse effects ; Triazoles/adverse effects ; Young Adult
Czasopismo naukowe
Tytuł :
In vitro and in vivo antiplasmodial activity of extracts and isolated constituents of Alstonia congensis root bark.
Autorzy :
Cimanga RK; Department of Medicinal Chemistry and Pharmacognosy, Laboratory of Pharmacognosy and Phytochemistry, University of Kinshasa, P.O. Box 212, Kinshasa XI, Democratic Republic of Congo; Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium. Electronic address: .
Nsaka SL; Department of Medicinal Chemistry and Pharmacognosy, Laboratory of Pharmacognosy and Phytochemistry, University of Kinshasa, P.O. Box 212, Kinshasa XI, Democratic Republic of Congo.
Tshodi ME; Department of Medicinal Chemistry and Pharmacognosy, Laboratory of Pharmacognosy and Phytochemistry, University of Kinshasa, P.O. Box 212, Kinshasa XI, Democratic Republic of Congo.
Mbamu BM; Department of Medicinal Chemistry and Pharmacognosy, Laboratory of Pharmacognosy and Phytochemistry, University of Kinshasa, P.O. Box 212, Kinshasa XI, Democratic Republic of Congo.
Kikweta CM; Department of Medicinal Chemistry and Pharmacognosy, Laboratory of Pharmacognosy and Phytochemistry, University of Kinshasa, P.O. Box 212, Kinshasa XI, Democratic Republic of Congo.
Makila FB; Departement of Pharmacology and Pharmacovigilance, Faculty of Pharmaceutical Sciences, University of Kinshasa, P.O. Box 212, Kinshasa XI, Democratic Republic of Congo.
Cos P; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.
Maes L; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.
Vlietinck AJ; Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.
Exarchou V; Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.
Tuenter E; Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.
Pieters L; Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.
Pokaż więcej
Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2019 Oct 05; Vol. 242, pp. 111736. Date of Electronic Publication: 2019 Feb 11.
Typ publikacji :
Journal Article
MeSH Terms :
Alstonia*
Antimalarials/*therapeutic use
Malaria/*drug therapy
Parasitemia/*drug therapy
Plant Extracts/*therapeutic use
Animals ; Antimalarials/pharmacology ; Cell Line ; Humans ; Malaria/parasitology ; Mice ; Parasitemia/parasitology ; Phytochemicals/analysis ; Phytochemicals/pharmacology ; Phytochemicals/therapeutic use ; Plant Bark ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Plant Roots ; Plasmodium/drug effects
Czasopismo naukowe

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