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Tytuł:
Protective Effect of CP690550 in MPTP-Induced Parkinson's Like Behavioural, Biochemical and Histological Alterations in Mice.
Autorzy:
Alshammari A; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Post Box 2455, Riyadh, 11451, Saudi Arabia.
Alharbi M; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Post Box 2455, Riyadh, 11451, Saudi Arabia.
Albekairi NA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Post Box 2455, Riyadh, 11451, Saudi Arabia.
Albekairi TH; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Post Box 2455, Riyadh, 11451, Saudi Arabia.
Alharbi OO; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Post Box 2455, Riyadh, 11451, Saudi Arabia.
Yeapuri P; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Singh S; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Export Promotion Industrial Park (EPIP) Zandaha Road, Dist: Vaishali, 844102, Bihar, India. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2022 Apr; Vol. 40 (2), pp. 564-572. Date of Electronic Publication: 2022 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Neuroprotective Agents*/pharmacology
Parkinson Disease*/drug therapy
Parkinson Disease*/pathology
Piperidines*/pharmacology
Pyrimidines*/pharmacology
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine ; Animals ; Cytokines ; Disease Models, Animal ; Dopaminergic Neurons ; Mice ; Mice, Inbred C57BL ; Parkinson Disease, Secondary
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Enough vs. More: Neuropsychological testing is more useful than genetic testing in the baseline evaluation of Parkinson disease.
Autorzy:
York MK; Neurology and Psychiatry and Behavioral Sciences, Section Head, Neuropsychology, Baylor College of Medicine, 7200 Cambridge Street, 9th Floor Neurology, Houston, TX, USA. Electronic address: .
Alcalay R; Movement Disorders Division, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Neurology, Member, Movement Disorders Division, Columbia University Irving Medical Center, USA. Electronic address: .
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Źródło:
Parkinsonism & related disorders [Parkinsonism Relat Disord] 2023 Jun; Vol. 111, pp. 105403. Date of Electronic Publication: 2023 May 11.
Typ publikacji:
Journal Article
MeSH Terms:
Parkinson Disease*/diagnosis
Parkinson Disease*/genetics
Parkinson Disease*/psychology
Cognitive Dysfunction*/diagnosis
Humans ; Quality of Life ; Neuropsychological Tests ; Genetic Testing ; Forecasting
Czasopismo naukowe
Szczegóły
Tytuł:
Incidence and outcomes of head injuries in people with and without Parkinson disease.
Autorzy:
Ilmaniemi S; School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
Tolppanen AM; School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
Herukka SK; Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
Hartikainen P; Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
Hartikainen S; School of Pharmacy, University of Eastern Finland, Kuopio, Finland.; Kuopio Research Centre of Geriatric Care, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
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Źródło:
European journal of neurology [Eur J Neurol] 2023 Jun; Vol. 30 (6), pp. 1648-1657. Date of Electronic Publication: 2023 Mar 26.
Typ publikacji:
Journal Article
MeSH Terms:
Parkinson Disease*/complications
Parkinson Disease*/epidemiology
Craniocerebral Trauma*/complications
Craniocerebral Trauma*/epidemiology
Brain Injuries, Traumatic*/epidemiology
Humans ; Incidence ; Comorbidity
Czasopismo naukowe
Szczegóły
Tytuł:
Impact of hepatitis C treatment status on risk of Parkinson's disease and secondary parkinsonism in the era of direct-acting antivirals.
Autorzy:
Selim R; Department of Gastroenterology and Hepatology, Henry Ford Health, Detroit, Michigan, United States.
Gordon SC; Department of Gastroenterology and Hepatology, Henry Ford Health, Detroit, Michigan, United States.; School of Medicine, Wayne State University, Detroit, Michigan, United States.
Zhou Y; Department of Public Health Sciences, Henry Ford Health, Detroit, Michigan, United States.
Zhang T; Center on Aging & Health, Johns Hopkins University, Baltimore, Maryland, United States.
Lu M; Center on Aging & Health, Johns Hopkins University, Baltimore, Maryland, United States.
Daida YG; Center for Integrated Health Care Research, Kaiser Permanente Hawaii, Honolulu, Hawaii, United States.
Boscarino JA; Biomedical Consulting Group LLC, Mahway, New Jersey, United States.
Schmidt MA; Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon, United States.
Trudeau S; Center on Aging & Health, Johns Hopkins University, Baltimore, Maryland, United States.
Rupp LB; Department of Health Policy and Health Systems Research, Henry Ford Health, Detroit, Michigan, United States.
Gonzalez HC; Department of Gastroenterology and Hepatology, Henry Ford Health, Detroit, Michigan, United States.; School of Medicine, Wayne State University, Detroit, Michigan, United States.
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Źródło:
Journal of viral hepatitis [J Viral Hepat] 2023 Jun; Vol. 30 (6), pp. 544-550. Date of Electronic Publication: 2023 Mar 20.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, P.H.S.; Research Support, Non-U.S. Gov't
MeSH Terms:
Parkinson Disease*/epidemiology
Diabetes Mellitus, Type 2*
Hepatitis C, Chronic*/complications
Hepatitis C, Chronic*/drug therapy
Hepatitis C*/drug therapy
Parkinson Disease, Secondary*/chemically induced
Parkinson Disease, Secondary*/complications
Parkinson Disease, Secondary*/drug therapy
Liver Neoplasms*/drug therapy
Carcinoma, Hepatocellular*/drug therapy
Humans ; Antiviral Agents/therapeutic use ; Cohort Studies ; Hepacivirus ; Sustained Virologic Response ; Liver Cirrhosis/complications
Czasopismo naukowe
Szczegóły
Tytuł:
EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation.
Autorzy:
Bademosi AT; VIB-KU Leuven Center for Brain & Disease Research, Leuven 3000, Belgium; KU Leuven, Department of Neurosciences, Leuven Brain Institute, Mission Lucidity, Leuven 3000, Belgium; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, St Lucia Campus, Brisbane, QLD 4072, Australia.
Decet M; VIB-KU Leuven Center for Brain & Disease Research, Leuven 3000, Belgium; KU Leuven, Department of Neurosciences, Leuven Brain Institute, Mission Lucidity, Leuven 3000, Belgium.
Kuenen S; VIB-KU Leuven Center for Brain & Disease Research, Leuven 3000, Belgium; KU Leuven, Department of Neurosciences, Leuven Brain Institute, Mission Lucidity, Leuven 3000, Belgium.
Calatayud C; VIB-KU Leuven Center for Brain & Disease Research, Leuven 3000, Belgium; KU Leuven, Department of Neurosciences, Leuven Brain Institute, Mission Lucidity, Leuven 3000, Belgium.
Swerts J; VIB-KU Leuven Center for Brain & Disease Research, Leuven 3000, Belgium; KU Leuven, Department of Neurosciences, Leuven Brain Institute, Mission Lucidity, Leuven 3000, Belgium.
Gallego SF; VIB-KU Leuven Center for Brain & Disease Research, Leuven 3000, Belgium; KU Leuven, Department of Neurosciences, Leuven Brain Institute, Mission Lucidity, Leuven 3000, Belgium.
Schoovaerts N; VIB-KU Leuven Center for Brain & Disease Research, Leuven 3000, Belgium; KU Leuven, Department of Neurosciences, Leuven Brain Institute, Mission Lucidity, Leuven 3000, Belgium.
Karamanou S; KU Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Leuven 3000, Belgium.
Louros N; VIB-KU Leuven Center for Brain & Disease Research, Leuven 3000, Belgium; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven 3000, Belgium.
Martin E; VIB-VUB Center for Structural Biology, Brussels 1050, Belgium; Department of Structural Biology Brussels, Vrije Universiteit Brussel, Brussels 1050, Belgium.
Sibarita JB; Interdisciplinary Institute for Neuroscience, University of Bordeaux, F-33000 Bordeaux, France.
Vints K; VIB-KU Leuven Center for Brain & Disease Research, Leuven 3000, Belgium; KU Leuven, Department of Neurosciences, Leuven Brain Institute, Mission Lucidity, Leuven 3000, Belgium; VIB Bio Core, KU Leuven, Leuven 3000, Belgium.
Gounko NV; VIB-KU Leuven Center for Brain & Disease Research, Leuven 3000, Belgium; KU Leuven, Department of Neurosciences, Leuven Brain Institute, Mission Lucidity, Leuven 3000, Belgium; VIB Bio Core, KU Leuven, Leuven 3000, Belgium.
Meunier FA; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, St Lucia Campus, Brisbane, QLD 4072, Australia; School of Biomedical Sciences, The University of Queensland, St Lucia Campus, Brisbane, QLD 4072, Australia.
Economou A; KU Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Leuven 3000, Belgium.
Versées W; VIB-VUB Center for Structural Biology, Brussels 1050, Belgium; Department of Structural Biology Brussels, Vrije Universiteit Brussel, Brussels 1050, Belgium.
Rousseau F; VIB-KU Leuven Center for Brain & Disease Research, Leuven 3000, Belgium; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven 3000, Belgium.
Schymkowitz J; VIB-KU Leuven Center for Brain & Disease Research, Leuven 3000, Belgium; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven 3000, Belgium.
Soukup SF; Univ. Bordeaux, CNRS UMR 5293, F-33000 Bordeaux, France. Electronic address: .
Verstreken P; VIB-KU Leuven Center for Brain & Disease Research, Leuven 3000, Belgium; KU Leuven, Department of Neurosciences, Leuven Brain Institute, Mission Lucidity, Leuven 3000, Belgium. Electronic address: .
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Źródło:
Neuron [Neuron] 2023 May 03; Vol. 111 (9), pp. 1402-1422.e13. Date of Electronic Publication: 2023 Feb 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Parkinson Disease*/genetics
Parkinson Disease*/metabolism
Animals ; Humans ; Autophagy/genetics ; Calcium/metabolism ; Dopaminergic Neurons/metabolism ; Drosophila/metabolism ; Mutation/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
Aperiodic subthalamic activity predicts motor severity and stimulation response in Parkinson disease.
Autorzy:
Clark DL; Department of Clinical Neuroscience, Calgary, AB, Canada; Department of Psychiatry, University of Calgary, Calgary, AB, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Khalil T; Department of Clinical Neuroscience, Calgary, AB, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Kim LH; Department of Clinical Neuroscience, Calgary, AB, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Noor MS; Department of Clinical Neuroscience, Calgary, AB, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Luo F; Department of Clinical Neuroscience, Calgary, AB, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Kiss ZH; Department of Clinical Neuroscience, Calgary, AB, Canada; Department of Psychiatry, University of Calgary, Calgary, AB, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada. Electronic address: .
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Źródło:
Parkinsonism & related disorders [Parkinsonism Relat Disord] 2023 May; Vol. 110, pp. 105397. Date of Electronic Publication: 2023 Apr 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Parkinson Disease*/therapy
Parkinson Disease*/complications
Deep Brain Stimulation*
Subthalamic Nucleus*/physiology
Humans ; Treatment Outcome
Czasopismo naukowe
Szczegóły
Tytuł:
The impact of the COVID-19 pandemic on neuropsychiatric and sleep disorders, and quality of life in individuals with neurodegenerative and demyelinating diseases: a systematic review and meta-analysis of observational studies.
Autorzy:
de Oliveira MPB; Healthy Aging Research Laboratory, Department of Physical Therapy, Federal University of São Carlos, Washington Luis Highway, Km 235, São Carlos, São Paulo, Brazil. .
de Castro AEF; Physical Therapy Laboratory, Department of Physical Therapy, State University of Campinas, São Paulo, Campinas, Brazil.
Miri AL; Neurofunctional Physical Therapy Research Group, Department of Physical Therapy, State University of Londrina, Londrina, Paraná, Brazil.
Lima CR; Mechanisms of Spinal Manual Therapy Laboratory, Department of Physical Therapy, The University of Alabama at Birmingham, Birmingham, AL, USA.
Truax BD; Department of Medicine, Division of Pulmonary, Allergy and Critical Care, The University of Alabama at Birmingham, Birmingham, AL, USA.
Probst VS; Neurofunctional Physical Therapy Research Group, Department of Physical Therapy, State University of Londrina, Londrina, Paraná, Brazil.
Smaili SM; Neurofunctional Physical Therapy Research Group, Department of Physical Therapy, State University of Londrina, Londrina, Paraná, Brazil.
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Źródło:
BMC neurology [BMC Neurol] 2023 Apr 12; Vol. 23 (1), pp. 150. Date of Electronic Publication: 2023 Apr 12.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:
COVID-19*/epidemiology
Sleep Initiation and Maintenance Disorders*/epidemiology
Sleep Wake Disorders*/epidemiology
Parkinson Disease*/complications
Parkinson Disease*/epidemiology
Demyelinating Diseases*
Humans ; Pandemics ; Quality of Life ; Cross-Sectional Studies ; Depression/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clozapine: Efficacy for Parkinson Disease psychosis in patients refractory to pimavanserin.
Autorzy:
Thames BH; Houston Methodist Neurological Institute, Houston Methodist Hospital, Houston, TX, USA.
Ondo WG; Weill Cornel Medical College, USA. Electronic address: .
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Źródło:
Parkinsonism & related disorders [Parkinsonism Relat Disord] 2023 Apr; Vol. 109, pp. 105356. Date of Electronic Publication: 2023 Mar 05.
Typ publikacji:
Letter
MeSH Terms:
Clozapine*/therapeutic use
Parkinson Disease*/complications
Parkinson Disease*/drug therapy
Antipsychotic Agents*/therapeutic use
Psychotic Disorders*/etiology
Psychotic Disorders*/complications
Humans ; Female ; Male
Opinia redakcyjna
Szczegóły
Tytuł:
Who is at Risk of Parkinson Disease? Refining the Preclinical Phase of GBA1 and LRRK2 Variant Carriers: a Clinical, Biochemical, and Imaging Approach.
Autorzy:
Menozzi E; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Montgomery County, MD, 20815, USA.
Schapira AHV; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Montgomery County, MD, 20815, USA.
Blandini F; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.; Ca'Granda IRCCS Foundation-Ospedale Maggiore Policlinico, Milan, Italy.
Avenali M; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy. .; IRCCS Mondino Foundation, Neurorehabilitation Unit and Movement Disorder Center, Pavia, Italy. .
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Źródło:
Current neurology and neuroscience reports [Curr Neurol Neurosci Rep] 2023 Apr; Vol. 23 (4), pp. 121-130. Date of Electronic Publication: 2023 Mar 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Parkinson Disease*/diagnostic imaging
Parkinson Disease*/genetics
Humans ; Glucosylceramidase/genetics ; Heterozygote ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/genetics ; Leukocytes, Mononuclear ; Longitudinal Studies ; Mutation ; Prodromal Symptoms
Czasopismo naukowe
Szczegóły
Tytuł:
Timely referral for device-aided therapy in Parkinson's disease. Development of a screening tool.
Autorzy:
Moes HR; University of Groningen, University Medical Center Groningen, Department of Neurology, Groningen, the Netherlands. Electronic address: .
Ten Kate JM; University of Groningen, University Medical Center Groningen, Department of Neurology, Groningen, the Netherlands.
Portman AT; Treant Zorggroep, Department of Neurology, Stadskanaal, the Netherlands.
van Harten B; Medical Center Leeuwarden, Department of Neurology, Leeuwarden, the Netherlands.
van Kesteren ME; Isala, Department of Neurology, Zwolle, the Netherlands.
Mondria T; Antonius Hospital, Department of Neurology, Sneek, the Netherlands.
Lunter G; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, the Netherlands.
Buskens E; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, the Netherlands.
van Laar T; University of Groningen, University Medical Center Groningen, Department of Neurology, Groningen, the Netherlands.
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Źródło:
Parkinsonism & related disorders [Parkinsonism Relat Disord] 2023 Apr; Vol. 109, pp. 105359. Date of Electronic Publication: 2023 Mar 08.
Typ publikacji:
Observational Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Parkinson Disease*/therapy
Parkinson Disease*/drug therapy
Dyskinesias*/drug therapy
Humans ; Cross-Sectional Studies ; Levodopa/therapeutic use ; Referral and Consultation ; Antiparkinson Agents/therapeutic use
Czasopismo naukowe
Szczegóły
Tytuł:
Screening for Fabry disease in a series of Parkinson's disease patients and literature review.
Autorzy:
Perillo S; Department of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Via Pansini 5, 80131, Naples, Italy.
Palmieri GR; Department of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Via Pansini 5, 80131, Naples, Italy.
Del Moral MO; Centogene GmbH, Rostock, Germany.
De Michele G; Department of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Via Pansini 5, 80131, Naples, Italy.
Giglio A; Department of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Via Pansini 5, 80131, Naples, Italy.
Cuomo N; Department of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Via Pansini 5, 80131, Naples, Italy.
Pane C; Department of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Via Pansini 5, 80131, Naples, Italy.
Bauer P; Centogene GmbH, Rostock, Germany.
De Michele G; Department of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Via Pansini 5, 80131, Naples, Italy.
De Rosa A; Department of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Via Pansini 5, 80131, Naples, Italy. .
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Źródło:
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2023 Apr; Vol. 44 (4), pp. 1235-1241. Date of Electronic Publication: 2022 Dec 22.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Fabry Disease*/complications
Fabry Disease*/diagnosis
Fabry Disease*/genetics
Parkinson Disease*/complications
Parkinson Disease*/diagnosis
Parkinson Disease*/genetics
Parkinson Disease, Secondary*
Male ; Humans ; Female ; alpha-Galactosidase/genetics ; Mutation/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
Physiological measures and anatomical correlates of subthalamic deep brain stimulation effect on gait in Parkinson's disease.
Autorzy:
Agharazi H; Louis Stokes Cleveland VA Medical Center, Cleveland, OH, United States of America.
Hardin EC; Louis Stokes Cleveland VA Medical Center, Cleveland, OH, United States of America; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States of America.
Flannery K; Louis Stokes Cleveland VA Medical Center, Cleveland, OH, United States of America.
Beylergil SB; Louis Stokes Cleveland VA Medical Center, Cleveland, OH, United States of America.
Noecker A; Department of Biomedical Engineering, Duke University, Durham, NC, United States of America.
Kilbane C; Neurological Institute, University Hospitals, Cleveland, OH, United States of America; Department of Neurology, Case Western Reserve University, Cleveland, OH, United States of America.
Factor SA; Jean and Paul Amos Parkinson's Disease and Movement Disorder Program, Department of Neurology, Emory University, Atlanta, GA, United States of America.
McIntyre C; Department of Biomedical Engineering, Duke University, Durham, NC, United States of America.
Shaikh AG; Louis Stokes Cleveland VA Medical Center, Cleveland, OH, United States of America; Neurological Institute, University Hospitals, Cleveland, OH, United States of America; Department of Neurology, Case Western Reserve University, Cleveland, OH, United States of America; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States of America. Electronic address: .
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Źródło:
Journal of the neurological sciences [J Neurol Sci] 2023 Jun 15; Vol. 449, pp. 120647. Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Parkinson Disease*/complications
Parkinson Disease*/therapy
Deep Brain Stimulation*/methods
Subthalamic Nucleus*/physiology
Humans ; Gait/physiology ; Walking
Czasopismo naukowe
Szczegóły
Tytuł:
Pallidal activities during sleep and sleep decoding in dystonia, Huntington's, and Parkinson's disease.
Autorzy:
Yin Z; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jiang Y; Department of Functional Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China; Beijing Key Laboratory of Neurostimulation, Beijing, China.
Merk T; Movement Disorder and Neuromodulation Unit, Department of Neurology, Charité - Campus Mitte, Charite - Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany.
Neumann WJ; Movement Disorder and Neuromodulation Unit, Department of Neurology, Charité - Campus Mitte, Charite - Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany.
Ma R; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
An Q; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Bai Y; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhao B; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Xu Y; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Fan H; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhang Q; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Qin G; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhang N; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; Department of Neuropsychiatry, Behavioral Neurology and Sleep Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Ma J; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; Department of Neuropsychiatry, Behavioral Neurology and Sleep Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhang H; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Liu H; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Shi L; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yang A; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Meng F; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhu G; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. Electronic address: .
Zhang J; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; Department of Functional Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China; Beijing Key Laboratory of Neurostimulation, Beijing, China. Electronic address: .
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Źródło:
Neurobiology of disease [Neurobiol Dis] 2023 Jun 15; Vol. 182, pp. 106143. Date of Electronic Publication: 2023 May 03.
Typ publikacji:
Journal Article
MeSH Terms:
Dystonia*
Parkinson Disease*/complications
Parkinson Disease*/therapy
Deep Brain Stimulation*/methods
Dystonic Disorders*
Humans ; Globus Pallidus ; Sleep
Czasopismo naukowe
Szczegóły
Tytuł:
Normalization effect of dopamine replacement therapy on brain functional connectome in Parkinson's disease.
Autorzy:
Wu C; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wu H; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhou C; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Guan X; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Guo T; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Cao Z; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wu J; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Liu X; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Chen J; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wen J; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Qin J; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Tan S; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Duanmu X; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhang B; Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Huang P; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xu X; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhang M; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
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Źródło:
Human brain mapping [Hum Brain Mapp] 2023 Jun 15; Vol. 44 (9), pp. 3845-3858. Date of Electronic Publication: 2023 May 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Parkinson Disease*/diagnostic imaging
Parkinson Disease*/drug therapy
Parkinson Disease*/complications
Connectome*/methods
Humans ; Dopamine ; Levodopa/therapeutic use ; Levodopa/pharmacology ; Retrospective Studies ; Brain ; Magnetic Resonance Imaging/methods
Czasopismo naukowe
Szczegóły
Tytuł:
From Lysosomal Storage Disorders to Parkinson's Disease - Challenges and Opportunities.
Autorzy:
Mächtel R; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany.
Boros FA; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany.
Dobert JP; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany.
Arnold P; Institute of Functional and Clinical Anatomy, Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Germany. Electronic address: .
Zunke F; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany. Electronic address: .
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Źródło:
Journal of molecular biology [J Mol Biol] 2023 Jun 15; Vol. 435 (12), pp. 167932. Date of Electronic Publication: 2022 Dec 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Parkinson Disease*/genetics
Parkinson Disease*/metabolism
Lysosomal Storage Diseases*/genetics
Lysosomal Storage Diseases*/metabolism
Humans ; Hydrolases/metabolism ; Lysosomes/metabolism ; Neurons/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Role of Autophagy Pathway in Parkinson's Disease and Related Genetic Neurological Disorders.
Autorzy:
Themistokleous C; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK of Dundee, Dundee DD1 5EH, UK; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA. Electronic address: https://twitter.com/ChrisTmsk.
Bagnoli E; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK of Dundee, Dundee DD1 5EH, UK; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA. Electronic address: https://twitter.com/EnricoBagnoli2.
Parulekar R; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK of Dundee, Dundee DD1 5EH, UK.
Muqit MMK; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK of Dundee, Dundee DD1 5EH, UK; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA. Electronic address: .
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Źródło:
Journal of molecular biology [J Mol Biol] 2023 Jun 15; Vol. 435 (12), pp. 168144. Date of Electronic Publication: 2023 May 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Parkinson Disease*/genetics
Parkinson Disease*/metabolism
Humans ; Autophagy/genetics ; Mitophagy/genetics ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism ; Protein Kinases/genetics ; Protein Kinases/metabolism ; Central Nervous System
Czasopismo naukowe
Szczegóły
Tytuł:
Structural Mechanisms of Mitochondrial Quality Control Mediated by PINK1 and Parkin.
Autorzy:
Trempe JF; Department of Pharmacology & Therapeutics, McGill University, Montreal, Quebec, Canada; Centre de Recherche en Biologie Structurale, Quebec, Canada. Electronic address: https://twitter.com/jftrempe.
Gehring K; Department of Biochemistry, McGill University, Montreal, Quebec, Canada; Centre de Recherche en Biologie Structurale, Quebec, Canada. Electronic address: https://twitter.com/kalle_gehring.
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Źródło:
Journal of molecular biology [J Mol Biol] 2023 Jun 15; Vol. 435 (12), pp. 168090. Date of Electronic Publication: 2023 Apr 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neurodegenerative Diseases*/metabolism
Parkinson Disease*/genetics
Parkinson Disease*/metabolism
Humans ; Ubiquitin-Protein Ligases/metabolism ; Ubiquitination ; Mitochondria/metabolism ; Protein Kinases/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Short-term plasticity of the motor cortex compensates for bradykinesia in Parkinson's disease.
Autorzy:
Guerra A; IRCCS Neuromed, Pozzilli, IS 86077, Italy; Department of Human Neurosciences, Sapienza University of Rome, Rome 00185, Italy.
Colella D; Department of Human Neurosciences, Sapienza University of Rome, Rome 00185, Italy.
Cannavacciuolo A; IRCCS Neuromed, Pozzilli, IS 86077, Italy.
Giangrosso M; Department of Human Neurosciences, Sapienza University of Rome, Rome 00185, Italy.
Paparella G; IRCCS Neuromed, Pozzilli, IS 86077, Italy.
Fabbrini G; IRCCS Neuromed, Pozzilli, IS 86077, Italy; Department of Human Neurosciences, Sapienza University of Rome, Rome 00185, Italy.
Berardelli A; IRCCS Neuromed, Pozzilli, IS 86077, Italy; Department of Human Neurosciences, Sapienza University of Rome, Rome 00185, Italy.
Bologna M; IRCCS Neuromed, Pozzilli, IS 86077, Italy; Department of Human Neurosciences, Sapienza University of Rome, Rome 00185, Italy. Electronic address: .
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Źródło:
Neurobiology of disease [Neurobiol Dis] 2023 Jun 15; Vol. 182, pp. 106137. Date of Electronic Publication: 2023 Apr 27.
Typ publikacji:
Journal Article
MeSH Terms:
Parkinson Disease*/complications
Parkinson Disease*/therapy
Motor Cortex*
Humans ; Hypokinesia/etiology ; Transcranial Magnetic Stimulation/methods ; Evoked Potentials, Motor ; gamma-Aminobutyric Acid
Czasopismo naukowe
Szczegóły
Tytuł:
Common Mechanisms Underlying α-Synuclein-Induced Mitochondrial Dysfunction in Parkinson's Disease.
Autorzy:
Sohrabi T; Department of Biological Sciences, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan 45137-66731, Iran.
Mirzaei-Behbahani B; Department of Biological Sciences, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan 45137-66731, Iran.
Zadali R; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
Pirhaghi M; Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Morozova-Roche LA; Department of Medical Biochemistry and Biophysics, Umeå University, 90187 Umeå, Sweden.
Meratan AA; Department of Biological Sciences, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan 45137-66731, Iran. Electronic address: .
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Źródło:
Journal of molecular biology [J Mol Biol] 2023 Jun 15; Vol. 435 (12), pp. 167992. Date of Electronic Publication: 2023 Feb 02.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Parkinson Disease*/genetics
Parkinson Disease*/metabolism
Humans ; alpha-Synuclein/genetics ; alpha-Synuclein/metabolism ; Mitochondria/metabolism ; Oxidative Stress/genetics ; Antioxidants/metabolism ; Dopaminergic Neurons/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
α-Synuclein Conformational Strains as Drivers of Phenotypic Heterogeneity in Neurodegenerative Diseases.
Autorzy:
So RWL; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada; Department of Biochemistry, University of Toronto, Toronto, ON, Canada. Electronic address: https://twitter.com/xsakuraphie.
Watts JC; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada; Department of Biochemistry, University of Toronto, Toronto, ON, Canada. Electronic address: https://twitter.com/JoelWattsLab.
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Źródło:
Journal of molecular biology [J Mol Biol] 2023 Jun 15; Vol. 435 (12), pp. 168011. Date of Electronic Publication: 2023 Feb 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Synucleinopathies*/pathology
Parkinson Disease*/genetics
Parkinson Disease*/pathology
Multiple System Atrophy*/genetics
Multiple System Atrophy*/pathology
Animals ; Humans ; alpha-Synuclein/chemistry ; Brain/metabolism
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 55834

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