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Wyszukujesz frazę ""Parkinson Disease, Secondary"" wg kryterium: Temat


Tytuł :
TRPV4 contributes to ER stress: Relation to apoptosis in the MPP -induced cell model of Parkinson's disease.
Autorzy :
Liu N; Faculty of Life science and Technology, Kunming University of Science and Technology, Kunming 650500, China; Department of Anesthesiology, The First People's Hospital of Yunnan Province, Kunming 650032, China.
Liu J; Medical School, Kunming University of Science and Technology, Kunming 650500, China.
Wen X; Medical School, Kunming University of Science and Technology, Kunming 650500, China.
Bai L; Faculty of Life science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Shao R; Medical School, Kunming University of Science and Technology, Kunming 650500, China.
Bai J; Medical School, Kunming University of Science and Technology, Kunming 650500, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Nov 15; Vol. 261, pp. 118461. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Endoplasmic Reticulum Stress*
Parkinson Disease, Secondary/*pathology
TRPV Cation Channels/*metabolism
1-Methyl-4-phenylpyridinium ; Animals ; Cell Survival ; PC12 Cells ; Parkinson Disease, Secondary/genetics ; Parkinson Disease, Secondary/metabolism ; Rats ; TRPV Cation Channels/analysis ; TRPV Cation Channels/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
Case Report: Dengue Virus-Triggered Parkinsonism in an Adolescent.
Autorzy :
Panda PK; Pediatric Neurology Division, Department of Pediatrics, All India Institute of Medical Sciences, Rishikesh, India.
Sharawat IK; Pediatric Neurology Division, Department of Pediatrics, All India Institute of Medical Sciences, Rishikesh, India.
Bolia R; Department of Pediatrics, All India Institute of Medical Sciences, Rishikesh, India.
Shrivastava Y; Department of Pediatrics, All India Institute of Medical Sciences, Rishikesh, India.
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Źródło :
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2020 Aug; Vol. 103 (2), pp. 851-854. Date of Electronic Publication: 2020 Apr 30.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Dengue/*complications
Parkinson Disease, Secondary/*etiology
Adolescent ; Antiparkinson Agents/therapeutic use ; Brain/diagnostic imaging ; Carbidopa/therapeutic use ; Diffusion Magnetic Resonance Imaging ; Drug Combinations ; Electroencephalography ; Humans ; India ; Levodopa/therapeutic use ; Magnetic Resonance Imaging ; Male ; Parkinson Disease, Secondary/diagnostic imaging ; Parkinson Disease, Secondary/drug therapy ; Parkinson Disease, Secondary/physiopathology ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Psychotropic medications induced parkinsonism and akathisia in people attending follow-up treatment at Jimma Medical Center, Psychiatry Clinic.
Autorzy :
Kumsa A; Department of Psychiatry, Institute of Health, Jimma University, Jimma, Ethiopia.
Agenagnew L; Department of Psychiatry, Institute of Health, Jimma University, Jimma, Ethiopia.
Alemu B; Department of Psychiatry, Institute of Health, Jimma University, Jimma, Ethiopia.
Girma S; Department of Psychiatry, Institute of Health, Jimma University, Jimma, Ethiopia.
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Źródło :
PloS one [PLoS One] 2020 Jul 02; Vol. 15 (7), pp. e0235365. Date of Electronic Publication: 2020 Jul 02 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Parkinson Disease, Secondary*/chemically induced
Parkinson Disease, Secondary*/epidemiology
Akathisia, Drug-Induced/*epidemiology
Antipsychotic Agents/*adverse effects
Schizophrenia/*drug therapy
Substance-Related Disorders/*epidemiology
Adolescent ; Adult ; Aftercare ; Ambulatory Care Facilities ; Antipsychotic Agents/therapeutic use ; Cross-Sectional Studies ; Ethiopia/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Prevalence ; Psychiatry ; Schizophrenia/epidemiology ; Young Adult
Czasopismo naukowe
Tytuł :
Drp1, a potential therapeutic target for Parkinson's disease, is involved in olfactory bulb pathological alteration in the Rotenone-induced rat model.
Autorzy :
Zhang X; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, PR China; Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou University, Yangzhou 225001, PR China; Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, PR China. Electronic address: .
Huang W; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, PR China.
Shao Q; Department of Pharmacy, Peking University People's Hospital, Beijing 100044, PR China.
Yang Y; Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou 730000, PR China; key Laboratory for Gastrointestinal Diseases of Gansu Province, Lanzhou University, Lanzhou, PR China.
Xu Z; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, PR China.
Chen J; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, PR China.
Zhang X; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, PR China.
Ge X; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, PR China; Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou University, Yangzhou 225001, PR China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Jun 01; Vol. 325, pp. 1-13. Date of Electronic Publication: 2020 Feb 20.
Typ publikacji :
Journal Article
MeSH Terms :
Dynamins/*genetics
Olfactory Bulb/*pathology
Parkinson Disease, Secondary/*genetics
Parkinson Disease, Secondary/*pathology
Rotenone/*toxicity
Uncoupling Agents/*toxicity
Animals ; Dynamins/drug effects ; Inflammasomes/genetics ; Male ; Mitochondria/drug effects ; Mitochondria/pathology ; Movement Disorders/pathology ; Movement Disorders/psychology ; NF-kappa B/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Neurons/pathology ; Nitric Oxide Synthase Type II/biosynthesis ; Nitric Oxide Synthase Type II/genetics ; Parkinson Disease, Secondary/chemically induced ; Rats ; Rats, Sprague-Dawley ; Smell/genetics ; Tyrosine 3-Monooxygenase/metabolism
Czasopismo naukowe
Tytuł :
Predicting Early Stage Drug Induced Parkinsonism using Unsupervised and Supervised Machine Learning.
Autorzy :
Nair P
Trisno R
Baghini MS
Pendharkar G
Chung H
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Źródło :
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference [Annu Int Conf IEEE Eng Med Biol Soc] 2020 Jul; Vol. 2020, pp. 776-779.
Typ publikacji :
Journal Article
MeSH Terms :
Parkinson Disease, Secondary*
Supervised Machine Learning*
Algorithms ; Humans ; Logistic Models ; Tremor
Czasopismo naukowe
Tytuł :
D1-mGlu5 heteromers mediate noncanonical dopamine signaling in Parkinson's disease.
Autorzy :
Sebastianutto I; Basal Ganglia Pathophysiology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Goyet E; Institut de Génomique Fonctionnelle (IGF), University of Montpellier, CNRS, INSERM, Montpellier, France.
Andreoli L; Basal Ganglia Pathophysiology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Font-Ingles J; Institut de Génomique Fonctionnelle (IGF), University of Montpellier, CNRS, INSERM, Montpellier, France.
Moreno-Delgado D; Institut de Génomique Fonctionnelle (IGF), University of Montpellier, CNRS, INSERM, Montpellier, France.; Department of Neuroscience Research, UCB Pharma, Braine l'Alleud, Belgium.
Bouquier N; Institut de Génomique Fonctionnelle (IGF), University of Montpellier, CNRS, INSERM, Montpellier, France.
Jahannault-Talignani C; Institut de Génomique Fonctionnelle (IGF), University of Montpellier, CNRS, INSERM, Montpellier, France.
Moutin E; Institut de Génomique Fonctionnelle (IGF), University of Montpellier, CNRS, INSERM, Montpellier, France.
Di Menna L; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Neuromed, Pozzilli, Italy.
Maslava N; Basal Ganglia Pathophysiology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Pin JP; Institut de Génomique Fonctionnelle (IGF), University of Montpellier, CNRS, INSERM, Montpellier, France.
Fagni L; Institut de Génomique Fonctionnelle (IGF), University of Montpellier, CNRS, INSERM, Montpellier, France.
Nicoletti F; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Neuromed, Pozzilli, Italy.; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy.
Ango F; Institut de Génomique Fonctionnelle (IGF), University of Montpellier, CNRS, INSERM, Montpellier, France.
Cenci MA; Basal Ganglia Pathophysiology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Perroy J; Institut de Génomique Fonctionnelle (IGF), University of Montpellier, CNRS, INSERM, Montpellier, France.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2020 Mar 02; Vol. 130 (3), pp. 1168-1184.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
MAP Kinase Signaling System*
Corpus Striatum/*metabolism
Neurons/*metabolism
Parkinson Disease, Secondary/*metabolism
Receptor, Metabotropic Glutamate 5/*metabolism
Receptors, Dopamine D1/*metabolism
Animals ; Corpus Striatum/pathology ; HEK293 Cells ; Humans ; Mice ; Mice, Knockout ; Multiprotein Complexes/agonists ; Multiprotein Complexes/genetics ; Multiprotein Complexes/metabolism ; Neurons/pathology ; Parkinson Disease, Secondary/drug therapy ; Parkinson Disease, Secondary/genetics ; Parkinson Disease, Secondary/pathology ; Rats ; Receptor, Metabotropic Glutamate 5/genetics ; Receptors, Dopamine D1/agonists ; Receptors, Dopamine D1/genetics
Czasopismo naukowe
Tytuł :
Human autologous iPSC-derived dopaminergic progenitors restore motor function in Parkinson's disease models.
Autorzy :
Song B; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.
Cha Y; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.
Ko S; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.
Jeon J; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.
Lee N; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.
Seo H; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.; Department of Molecular and Life Sciences, Hanyang University, Ansan, Korea.
Park KJ; Department of Psychiatry and.
Lee IH; Department of Pediatrics.; Computational Health Informatics Program, Boston Children's Hospital, and.
Lopes C; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.
Feitosa M; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.
Luna MJ; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.
Jung JH; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.
Kim J; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.; Department of Molecular and Life Sciences, Hanyang University, Ansan, Korea.
Hwang D; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.
Cohen BM; Department of Psychiatry and.
Teicher MH; Department of Psychiatry and.
Leblanc P; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.
Carter BS; Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Kordower JH; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.
Bolshakov VY; Department of Psychiatry and.
Kong SW; Department of Pediatrics.; Computational Health Informatics Program, Boston Children's Hospital, and.
Schweitzer JS; Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Kim KS; Department of Psychiatry and.; Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2020 Feb 03; Vol. 130 (2), pp. 904-920.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Induced Pluripotent Stem Cells*/metabolism
Induced Pluripotent Stem Cells*/pathology
Induced Pluripotent Stem Cells*/transplantation
Motor Activity*
Parkinson Disease, Secondary*/metabolism
Parkinson Disease, Secondary*/pathology
Parkinson Disease, Secondary*/therapy
Recovery of Function*
Stem Cell Transplantation*
Animals ; Autografts ; Humans ; Male ; Rats ; Rats, Nude
Czasopismo naukowe
Tytuł :
Severe parkinsonism under treatment with antipsychotic drugs.
Autorzy :
Druschky K; Department of Neurology, University of Erlangen-Nuremberg, Schwabachanlage 6, 90451, Erlangen, Germany. .
Bleich S; Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Grohmann R; Department of Psychiatry and Psychotherapy, Ludwig Maximilian University of Munich, Nussbaumstraße 7, 80336, Munich, Germany.
Engel RR; Department of Psychiatry and Psychotherapy, Ludwig Maximilian University of Munich, Nussbaumstraße 7, 80336, Munich, Germany.
Toto S; Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Neyazi A; Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Däubl B; KRH Psychiatrie Wunstorf, Südstr. 25, 31515, Wunstorf, Germany.; KRH Psychiatrie Langenhagen, Langenhagen, Germany.
Stübner S; Department of Psychiatry and Psychotherapy, Ludwig Maximilian University of Munich, Nussbaumstraße 7, 80336, Munich, Germany.
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Źródło :
European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2020 Feb; Vol. 270 (1), pp. 35-47. Date of Electronic Publication: 2019 Aug 23.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Pharmacovigilance*
Antipsychotic Agents/*adverse effects
Drug Monitoring/*statistics & numerical data
Drug-Related Side Effects and Adverse Reactions/*epidemiology
Parkinson Disease, Secondary/*chemically induced
Parkinson Disease, Secondary/*epidemiology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Austria/epidemiology ; Drug Utilization/statistics & numerical data ; Drug-Related Side Effects and Adverse Reactions/physiopathology ; Female ; Germany/epidemiology ; Humans ; Male ; Middle Aged ; Parkinson Disease, Secondary/physiopathology ; Severity of Illness Index ; Switzerland/epidemiology ; Young Adult
Czasopismo naukowe
Tytuł :
Regular Aerobic Exercise-Alleviated Dysregulation of CAMKIIα Carbonylation to Mitigate Parkinsonism via Homeostasis of Apoptosis With Autophagy.
Autorzy :
Liu W; Hunan Provincial Key Laboratory of Physical Fitness and Sports Rehabilitation, Hunan Normal University, Changsha, Hunan, China (WL, RF, ZW, SL, CT, LL, DY); Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota (WL); School of Health & Kinesiology, Georgia Southern University, Statesboro, Georgia (LL); and Qingyuan People's Hospital, The Sixth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China (DY).
Fu R; Hunan Provincial Key Laboratory of Physical Fitness and Sports Rehabilitation, Hunan Normal University, Changsha, Hunan, China (WL, RF, ZW, SL, CT, LL, DY); Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota (WL); School of Health & Kinesiology, Georgia Southern University, Statesboro, Georgia (LL); and Qingyuan People's Hospital, The Sixth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China (DY).
Wang Z; Hunan Provincial Key Laboratory of Physical Fitness and Sports Rehabilitation, Hunan Normal University, Changsha, Hunan, China (WL, RF, ZW, SL, CT, LL, DY); Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota (WL); School of Health & Kinesiology, Georgia Southern University, Statesboro, Georgia (LL); and Qingyuan People's Hospital, The Sixth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China (DY).
Liu S; Hunan Provincial Key Laboratory of Physical Fitness and Sports Rehabilitation, Hunan Normal University, Changsha, Hunan, China (WL, RF, ZW, SL, CT, LL, DY); Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota (WL); School of Health & Kinesiology, Georgia Southern University, Statesboro, Georgia (LL); and Qingyuan People's Hospital, The Sixth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China (DY).
Tang C; Hunan Provincial Key Laboratory of Physical Fitness and Sports Rehabilitation, Hunan Normal University, Changsha, Hunan, China (WL, RF, ZW, SL, CT, LL, DY); Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota (WL); School of Health & Kinesiology, Georgia Southern University, Statesboro, Georgia (LL); and Qingyuan People's Hospital, The Sixth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China (DY).
Li L; Hunan Provincial Key Laboratory of Physical Fitness and Sports Rehabilitation, Hunan Normal University, Changsha, Hunan, China (WL, RF, ZW, SL, CT, LL, DY); Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota (WL); School of Health & Kinesiology, Georgia Southern University, Statesboro, Georgia (LL); and Qingyuan People's Hospital, The Sixth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China (DY).
Yin D; Hunan Provincial Key Laboratory of Physical Fitness and Sports Rehabilitation, Hunan Normal University, Changsha, Hunan, China (WL, RF, ZW, SL, CT, LL, DY); Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota (WL); School of Health & Kinesiology, Georgia Southern University, Statesboro, Georgia (LL); and Qingyuan People's Hospital, The Sixth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China (DY).
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Źródło :
Journal of neuropathology and experimental neurology [J Neuropathol Exp Neurol] 2020 Jan 01; Vol. 79 (1), pp. 46-61.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Autophagy*
Physical Conditioning, Animal*
Protein Carbonylation*
Calcium-Binding Proteins/*metabolism
Parkinson Disease, Secondary/*metabolism
Parkinson Disease, Secondary/*therapy
Aging/physiology ; Animals ; Beclin-1/metabolism ; Behavior, Animal ; Corpus Striatum/growth & development ; Corpus Striatum/metabolism ; Exercise Therapy ; Homeostasis ; Microtubule-Associated Proteins/genetics ; Microtubule-Associated Proteins/metabolism ; Oxidopamine ; Parkinson Disease, Secondary/psychology ; Rats ; alpha-Synuclein/genetics ; alpha-Synuclein/metabolism
Czasopismo naukowe
Tytuł :
Focused ultrasound enhanced intranasal delivery of brain derived neurotrophic factor produces neurorestorative effects in a Parkinson's disease mouse model.
Autorzy :
Ji R; Department of Biomedical Engineering, Columbia University, New York, New York, USA.
Smith M; Department of Biomedical Engineering, Columbia University, New York, New York, USA.
Niimi Y; Department of Biomedical Engineering, Columbia University, New York, New York, USA.
Karakatsani ME; Department of Biomedical Engineering, Columbia University, New York, New York, USA.
Murillo MF; Department of Biomedical Engineering, Columbia University, New York, New York, USA.
Jackson-Lewis V; Department of Pathology & Cell Biology, Columbia University, New York, New York, USA.; Department of the Center for Motor Neuron Biology and Disease, Columbia University, New York, New York, USA.; Department of the Columbia Translational Neuroscience Initiative, Columbia University, New York, New York, USA.
Przedborski S; Department of Pathology & Cell Biology, Columbia University, New York, New York, USA.; Department of Neurology, Columbia University, New York, New York, USA.; Department of the Center for Motor Neuron Biology and Disease, Columbia University, New York, New York, USA.; Department of the Columbia Translational Neuroscience Initiative, Columbia University, New York, New York, USA.
Konofagou EE; Department of Biomedical Engineering, Columbia University, New York, New York, USA. .; Department of Radiology, Columbia University, New York, New York, USA. .
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Źródło :
Scientific reports [Sci Rep] 2019 Dec 18; Vol. 9 (1), pp. 19402. Date of Electronic Publication: 2019 Dec 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Brain-Derived Neurotrophic Factor/*pharmacology
Dopamine/*genetics
Parkinson Disease/*therapy
Parkinson Disease, Secondary/*therapy
Tyrosine 3-Monooxygenase/*genetics
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/adverse effects ; Administration, Intranasal ; Animals ; Basal Ganglia/drug effects ; Basal Ganglia/pathology ; Basal Ganglia/radiation effects ; Blood-Brain Barrier/diagnostic imaging ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/radiation effects ; Brain/drug effects ; Brain/pathology ; Brain/radiation effects ; Corpus Striatum/diagnostic imaging ; Corpus Striatum/drug effects ; Corpus Striatum/radiation effects ; Disease Models, Animal ; Dopamine/biosynthesis ; Humans ; Mice ; Neuroprotective Agents/pharmacology ; Parkinson Disease/genetics ; Parkinson Disease/pathology ; Parkinson Disease, Secondary/chemically induced ; Parkinson Disease, Secondary/genetics ; Parkinson Disease, Secondary/pathology ; Substantia Nigra/diagnostic imaging ; Substantia Nigra/drug effects ; Substantia Nigra/radiation effects ; Ultrasonic Waves
Czasopismo naukowe
Tytuł :
Systems pharmacology based approach to investigate the in-vivo therapeutic efficacy of Albizia lebbeck (L.) in experimental model of Parkinson's disease.
Autorzy :
Saleem U; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan. .
Raza Z; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.
Anwar F; Riphah Institute of Pharmaceutical sciences, Riphah International University, Lahore, Pakistan.
Chaudary Z; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.
Ahmad B; Riphah Institute of Pharmaceutical sciences, Riphah International University, Lahore, Pakistan.
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Źródło :
BMC complementary and alternative medicine [BMC Complement Altern Med] 2019 Dec 05; Vol. 19 (1), pp. 352. Date of Electronic Publication: 2019 Dec 05.
Typ publikacji :
Journal Article
MeSH Terms :
Parkinson Disease, Secondary*/chemically induced
Parkinson Disease, Secondary*/drug therapy
Parkinson Disease, Secondary*/physiopathology
Plant Extracts*/administration & dosage
Plant Extracts*/pharmacology
Plant Extracts*/therapeutic use
Albizzia/*chemistry
Animals ; Behavior, Animal/drug effects ; Cerebral Cortex/drug effects ; Cerebral Cortex/pathology ; Disease Models, Animal ; Haloperidol/adverse effects ; Motor Skills/drug effects ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Novel application of the gray-level co-occurrence matrix analysis in the parvalbumin stained hippocampal gyrus dentatus in distinct rat models of Parkinson's disease.
Autorzy :
Rajkovic N; University of Belgrade, School of Medicine, Department of Biophysics, Belgrade, Serbia. Electronic address: .
Ciric J; University of Belgrade, Department of Neurobiology, Institute for Biological Research - Sinisa Stankovic, Belgrade, Serbia.
Milosevic N; University of Belgrade, School of Medicine, Department of Biophysics, Belgrade, Serbia.
Saponjic J; University of Belgrade, Department of Neurobiology, Institute for Biological Research - Sinisa Stankovic, Belgrade, Serbia.
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Źródło :
Computers in biology and medicine [Comput Biol Med] 2019 Dec; Vol. 115, pp. 103482. Date of Electronic Publication: 2019 Oct 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dentate Gyrus*/metabolism
Dentate Gyrus*/pathology
Image Processing, Computer-Assisted*
Interneurons*/metabolism
Interneurons*/pathology
Parkinson Disease, Secondary*/metabolism
Parkinson Disease, Secondary*/pathology
Parvalbumins/*metabolism
Animals ; Male ; Rats ; Rats, Wistar ; Staining and Labeling
Czasopismo naukowe
Tytuł :
Immature mDA neurons ameliorate motor deficits in a 6-OHDA Parkinson's disease mouse model and are functional after cryopreservation.
Autorzy :
Leitner D; Department of Cell, Developmental, and Regenerative Biology, Mount Sinai Icahn School of Medicine, New York, NY 10029, United States; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States; Huffington Foundation Center for Cell-Based Research in Parkinson's Disease, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.
Ramamoorthy M; Department of Cell, Developmental, and Regenerative Biology, Mount Sinai Icahn School of Medicine, New York, NY 10029, United States; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States; Huffington Foundation Center for Cell-Based Research in Parkinson's Disease, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.
Dejosez M; Department of Cell, Developmental, and Regenerative Biology, Mount Sinai Icahn School of Medicine, New York, NY 10029, United States; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States; Huffington Foundation Center for Cell-Based Research in Parkinson's Disease, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.
Zwaka TP; Department of Cell, Developmental, and Regenerative Biology, Mount Sinai Icahn School of Medicine, New York, NY 10029, United States; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States; Huffington Foundation Center for Cell-Based Research in Parkinson's Disease, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States. Electronic address: .
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Źródło :
Stem cell research [Stem Cell Res] 2019 Dec; Vol. 41, pp. 101617. Date of Electronic Publication: 2019 Oct 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Cryopreservation*
Dopaminergic Neurons*/metabolism
Dopaminergic Neurons*/pathology
Dopaminergic Neurons*/transplantation
Induced Pluripotent Stem Cells*/metabolism
Induced Pluripotent Stem Cells*/pathology
Mesencephalon*/metabolism
Mesencephalon*/pathology
Parkinson Disease, Secondary*/chemically induced
Parkinson Disease, Secondary*/metabolism
Parkinson Disease, Secondary*/pathology
Parkinson Disease, Secondary*/therapy
Animals ; Cell Line ; Heterografts ; Humans ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Oxidopamine/pharmacology
Czasopismo naukowe
Tytuł :
Effects of bromelain on motor responses following intra-medial forebrain bundle 6-OHDA injection in rat model of parkinsonism.
Autorzy :
Adu TS; Discipline of Human Physiology, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Private Bag X54001, Durban, South Africa. .
Mabandla MV; Discipline of Human Physiology, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Private Bag X54001, Durban, South Africa.
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Źródło :
Metabolic brain disease [Metab Brain Dis] 2019 Dec; Vol. 34 (6), pp. 1557-1564. Date of Electronic Publication: 2019 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*therapeutic use
Bromelains/*therapeutic use
Medial Forebrain Bundle/*drug effects
Motor Activity/*drug effects
Parkinson Disease, Secondary/*drug therapy
Animals ; Anti-Inflammatory Agents/pharmacology ; Behavior, Animal/drug effects ; Bromelains/pharmacology ; Cerebral Cortex/metabolism ; Corpus Striatum/metabolism ; Disease Models, Animal ; Dopaminergic Neurons/drug effects ; Dopaminergic Neurons/metabolism ; Male ; Medial Forebrain Bundle/metabolism ; Medial Forebrain Bundle/physiopathology ; Oxidopamine ; Parkinson Disease, Secondary/chemically induced ; Parkinson Disease, Secondary/metabolism ; Parkinson Disease, Secondary/physiopathology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
TLR4 deficiency has a protective effect in the MPTP/probenecid mouse model of Parkinson's disease.
Autorzy :
Shao QH; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Chen Y; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Li FF; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Wang S; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Zhang XL; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Yuan YH; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. .
Chen NH; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. .; College of Pharmacy, Hunan University of Chinese Medicine, Changsha, 410208, China. .
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Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2019 Dec; Vol. 40 (12), pp. 1503-1512. Date of Electronic Publication: 2019 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Parkinson Disease, Secondary/*physiopathology
Toll-Like Receptor 4/*physiology
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine ; Animals ; Astrocytes/metabolism ; Astrocytes/pathology ; Corpus Striatum/metabolism ; Corpus Striatum/pathology ; Dopaminergic Neurons/metabolism ; Dopaminergic Neurons/pathology ; Inflammasomes/metabolism ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Microglia/metabolism ; Microglia/pathology ; NF-kappa B p50 Subunit/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Parkinson Disease, Secondary/chemically induced ; Parkinson Disease, Secondary/genetics ; Pars Compacta/metabolism ; Pars Compacta/pathology ; Probenecid ; Signal Transduction/physiology ; Toll-Like Receptor 4/genetics ; Tyrosine 3-Monooxygenase/metabolism ; alpha-Synuclein/metabolism
Czasopismo naukowe
Tytuł :
Striatal overexpression of β-arrestin2 counteracts L-dopa-induced dyskinesia in 6-hydroxydopamine lesioned Parkinson's disease rats.
Autorzy :
Zhang ZR; Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
Zhang XR; Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
Luan XQ; Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
Wang XS; Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
Wang WW; The center of Traditional Chinese Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 325027, Wenzhou, China.
Wang XY; Department of Nephrology, The First People's Hospital of Huzhou, Zhejiang, 313000, PR China.
Shao B; Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China. Electronic address: .
Xie CL; Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China. Electronic address: .
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Źródło :
Neurochemistry international [Neurochem Int] 2019 Dec; Vol. 131, pp. 104543. Date of Electronic Publication: 2019 Sep 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiparkinson Agents*
Levodopa*
Dyskinesia, Drug-Induced/*therapy
Neostriatum/*metabolism
Parkinson Disease, Secondary/*therapy
beta-Arrestin 2/*biosynthesis
beta-Arrestin 2/*genetics
Adenoviridae/genetics ; Animals ; Dopamine and cAMP-Regulated Phosphoprotein 32/metabolism ; Dyskinesia, Drug-Induced/psychology ; Gene Deletion ; Genetic Therapy ; Genetic Vectors ; MAP Kinase Signaling System/drug effects ; Male ; Neostriatum/drug effects ; Parkinson Disease, Secondary/chemically induced ; Parkinson Disease, Secondary/psychology ; Phosphoproteins/drug effects ; Rats ; Rats, Sprague-Dawley ; Recovery of Function ; Transcription Factors/drug effects
Czasopismo naukowe
Tytuł :
Reciprocal cross-sensitization of D1 and D3 receptors following pharmacological stimulation in the hemiparkinsonian rat.
Autorzy :
Lanza K; Behavioral Neuroscience Program, Department of Psychology, Binghamton University, 4400 Vestal Parkway East, Binghamton, NY, 13902, USA.
Chemakin K; Behavioral Neuroscience Program, Department of Psychology, Binghamton University, 4400 Vestal Parkway East, Binghamton, NY, 13902, USA.
Lefkowitz S; Behavioral Neuroscience Program, Department of Psychology, Binghamton University, 4400 Vestal Parkway East, Binghamton, NY, 13902, USA.
Saito C; Behavioral Neuroscience Program, Department of Psychology, Binghamton University, 4400 Vestal Parkway East, Binghamton, NY, 13902, USA.
Chambers N; Behavioral Neuroscience Program, Department of Psychology, Binghamton University, 4400 Vestal Parkway East, Binghamton, NY, 13902, USA.
Bishop C; Behavioral Neuroscience Program, Department of Psychology, Binghamton University, 4400 Vestal Parkway East, Binghamton, NY, 13902, USA. .
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2020 Jan; Vol. 237 (1), pp. 155-165. Date of Electronic Publication: 2019 Aug 21.
Typ publikacji :
Journal Article
MeSH Terms :
Corpus Striatum/*metabolism
Dopamine Agonists/*pharmacology
Dyskinesia, Drug-Induced/*metabolism
Parkinson Disease, Secondary/*metabolism
Receptors, Dopamine D1/*metabolism
Receptors, Dopamine D3/*metabolism
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/pharmacology ; Animals ; Benzopyrans/pharmacology ; Corpus Striatum/drug effects ; Dopamine/metabolism ; Female ; Oxazines/pharmacology ; Oxidopamine ; Parkinson Disease, Secondary/chemically induced ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Vascular Parkinsonism by Infarctions at Different Locations on 18F-FP-CIT PET/CT.
Autorzy :
Kim C; From the Department of Medicine, Graduate School.
Kim DY; Department of Nuclear Medicine, Kyung Hee University Hospital, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Hong IK; Department of Nuclear Medicine, Kyung Hee University Hospital, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
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Źródło :
Clinical nuclear medicine [Clin Nucl Med] 2019 Nov; Vol. 44 (11), pp. e627-e628.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Positron Emission Tomography Computed Tomography*
Tropanes*
Brain Infarction/*complications
Parkinson Disease, Secondary/*diagnostic imaging
Parkinson Disease, Secondary/*etiology
Aged ; Female ; Humans ; Parkinson Disease, Secondary/pathology ; Parkinson Disease, Secondary/physiopathology
Czasopismo naukowe
Tytuł :
The effect of dextromethorphan use in Parkinson's disease: A 6-hydroxydopamine rat model and population-based study.
Autorzy :
Liu CT; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan; Department of Pharmacy Practice, Tri-Service General Hospital, Taipei, Taiwan; School of Pharmacy, National Defense Medical Center, Taipei, Taiwan.
Kao LT; Department of Pharmacy Practice, Tri-Service General Hospital, Taipei, Taiwan; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan; School of Public Health, National Defense Medical Center, Taipei, Taiwan.
Shih JH; Department of Pharmacy Practice, Tri-Service General Hospital, Taipei, Taiwan; School of Pharmacy, National Defense Medical Center, Taipei, Taiwan.
Chien WC; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan; School of Public Health, National Defense Medical Center, Taipei, Taiwan; Department of Medical Research, Tri-Service General Hospital, Taipei, Taiwan.
Chiu CH; Department of Nuclear Medicine, Tri-Service General Hospital, Taipei, Taiwan.
Ma KH; Department of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan.
Huang YS; Department of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan.
Cheng CY; Department of Nuclear Medicine, Tri-Service General Hospital, Taipei, Taiwan.
Shiue CY; Department of Nuclear Medicine, Tri-Service General Hospital, Taipei, Taiwan.
Li IH; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan; Department of Pharmacy Practice, Tri-Service General Hospital, Taipei, Taiwan; School of Pharmacy, National Defense Medical Center, Taipei, Taiwan; Department of Pharmacology, National Defense Medical Center, Taipei, Taiwan. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2019 Nov 05; Vol. 862, pp. 172639. Date of Electronic Publication: 2019 Sep 03.
Typ publikacji :
Journal Article
MeSH Terms :
Dextromethorphan/*administration & dosage
Parkinson Disease/*prevention & control
Parkinson Disease, Secondary/*prevention & control
Protective Agents/*administration & dosage
Aged ; Aged, 80 and over ; Animals ; Behavior Observation Techniques ; Behavior, Animal/drug effects ; Case-Control Studies ; Corpus Striatum/diagnostic imaging ; Corpus Striatum/metabolism ; Disease Models, Animal ; Dopamine Plasma Membrane Transport Proteins/analysis ; Dopamine Plasma Membrane Transport Proteins/metabolism ; Dose-Response Relationship, Drug ; Female ; Humans ; Male ; Oxidopamine/toxicity ; Parkinson Disease/epidemiology ; Parkinson Disease, Secondary/chemically induced ; Parkinson Disease, Secondary/pathology ; Positron-Emission Tomography ; Rats ; Rats, Sprague-Dawley ; Serotonin Plasma Membrane Transport Proteins/analysis ; Serotonin Plasma Membrane Transport Proteins/metabolism ; Taiwan/epidemiology ; X-Ray Microtomography
Czasopismo naukowe
Tytuł :
Psychostimulant use and the brain.
Autorzy :
Lappin JM; National Drug and Alcohol Research Centre (NDARC), University of New South Wales, Sydney, Australia.; School of Psychiatry, University of New South Wales, Sydney, Australia.
Sara GE; InforMH, NSW Ministry of Health, North Ryde, NSW, Australia.; Northern Clinical School, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.
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Źródło :
Addiction (Abingdon, England) [Addiction] 2019 Nov; Vol. 114 (11), pp. 2065-2077. Date of Electronic Publication: 2019 Jul 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Central Nervous System Stimulants/*adverse effects
Cognitive Dysfunction/*chemically induced
Parkinson Disease, Secondary/*chemically induced
Psychoses, Substance-Induced/*etiology
Seizures/*chemically induced
Stroke/*chemically induced
Amphetamine/adverse effects ; Amphetamine-Related Disorders/metabolism ; Amphetamine-Related Disorders/physiopathology ; Brain/metabolism ; Brain/physiopathology ; Cocaine/adverse effects ; Cocaine-Related Disorders/metabolism ; Cocaine-Related Disorders/physiopathology ; Cognitive Dysfunction/metabolism ; Cognitive Dysfunction/physiopathology ; Humans ; Methamphetamine/adverse effects ; N-Methyl-3,4-methylenedioxyamphetamine/adverse effects ; Parkinson Disease, Secondary/metabolism ; Parkinson Disease, Secondary/physiopathology ; Psychoses, Substance-Induced/metabolism ; Psychoses, Substance-Induced/physiopathology ; Seizures/metabolism ; Seizures/physiopathology ; Stroke/metabolism ; Stroke/physiopathology
Czasopismo naukowe

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