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Tytuł :
Electroacupuncture alleviates Parkinson disease and regulates the expression of brain-gut peptides.
Autorzy :
Yu J; Department of Massage, Heilongjiang Academy of Chinese Medical Sciences, 72-78 Xiang'an Street, Harbin 150036, People's Republic of China.
Min D; Department of Rehabilitation Medicine, Heilongjiang Provincial Hospital, No. 82 Zhongshan Road, Xiangfang District, Harbin 150036, People's Republic of China.
Bai Y; Department of Acupuncture, Heilongjiang Academy of Chinese Medical Sciences, 72-78 Xiang'an Street, Harbin 150036, People's Republic of China.
Qu L; Department of Massage, Heilongjiang Academy of Chinese Medical Sciences, 72-78 Xiang'an Street, Harbin 150036, People's Republic of China.
Zou T; Department of Acupuncture, Heilongjiang Academy of Chinese Medical Sciences, 72-78 Xiang'an Street, Harbin 150036, People's Republic of China.
Wang S; Department of Acupuncture, Heilongjiang Academy of Chinese Medical Sciences, 72-78 Xiang'an Street, Harbin 150036, People's Republic of China.
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Źródło :
Experimental animals [Exp Anim] 2020 Nov 12; Vol. 69 (4), pp. 448-460. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Electroacupuncture*
Gene Expression Regulation*
Brain/*metabolism
Neuropeptides/*genetics
Neuropeptides/*metabolism
Parkinson Disease/*genetics
Parkinson Disease/*therapy
Animals ; Anxiety ; Disease Models, Animal ; Dyskinesias ; Male ; Oxidative Stress ; Parkinson Disease/metabolism ; Parkinson Disease/psychology ; Rats, Sprague-Dawley ; Spatial Memory
Czasopismo naukowe
Tytuł :
In vivo distribution of α-synuclein in multiple tissues and biofluids in Parkinson disease.
Autorzy :
Chahine LM; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany. .
Beach TG; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Brumm MC; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Adler CH; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Coffey CS; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Mosovsky S; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Caspell-Garcia C; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Serrano GE; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Munoz DG; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
White CL 3rd; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Crary JF; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Jennings D; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Taylor P; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Foroud T; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Arnedo V; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Kopil CM; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Riley L; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Dave KD; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
Mollenhauer B; From the Department of Neurology (L.M.C., S.M.), University of Pittsburgh, PA; Banner Sun Health Research Institute (T.G.B., G.E.S.), Sun City, AZ; University of Iowa (M.C.B., C.S.C., C.C.-G.), Iowa City; Department of Neurology (C.H.A.), Mayo Clinic College of Medicine, Scottsdale, AZ; St. Michael's Hospital (D.G.M.), Toronto, Canada; University of Texas Southwestern Medical School (C.L.W.), Dallas; Icahn School of Medicine at Mount Sinai (J.F.C.), New York, NY; Institute for Neurodegenerative Disorders (D.J.), New Haven, CT; BioLegend Inc. (P.T.), Dedham, MA; Indiana University (T.F.), Indianapolis; The Michael J. Fox Foundation for Parkinson's Research (V.A., C.M.K., L.R., K.D.D.), New York, NY; and Department of Neurology (B.M.), Center of Parkinsonism and Movement Disorders Paracelsus-Elena Klinik Kassel and University Medical Center Göttingen, Germany.
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Corporate Authors :
Systemic Synuclein Sampling Study
Źródło :
Neurology [Neurology] 2020 Sep 01; Vol. 95 (9), pp. e1267-e1284. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*diagnostic imaging
Colon/*metabolism
Parkinson Disease/*metabolism
Saliva/*metabolism
Skin/*metabolism
Submandibular Gland/*metabolism
alpha-Synuclein/*metabolism
Adult ; Aged ; Aged, 80 and over ; Biopsy ; Brain/metabolism ; Case-Control Studies ; Dopamine Plasma Membrane Transport Proteins ; Female ; Humans ; Male ; Middle Aged ; Parkinson Disease/diagnosis ; Sensitivity and Specificity ; Tomography, Emission-Computed, Single-Photon ; alpha-Synuclein/blood ; alpha-Synuclein/cerebrospinal fluid
Czasopismo naukowe
Tytuł :
The Application of Resting Magnetic Resonance Imaging in the Cognitive Judgment of Parkinson.
Autorzy :
Mu L; Department of Radiology, The First Hospital of Jilin University, Changchun, Jilin, China.
Zhou Q; Cadre's Ward, The First Hospital of Jilin University, Changchun, Jilin, China.
Sun D; Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, Changchun, Jilin, China.
Wang M; Department of Pathology, Jilin Provincial Cancer Hospital, Changchun, China.
Chai X; Department of Breast Surgery, Jilin Cancer Hospital, Changchun, China.
Wang M; Center of Reproductive Medicine, Center of Prenatal Diagnosis, The First Hospital of Jilin University, Changchun, Jilin, China. Electronic address: .
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Źródło :
World neurosurgery [World Neurosurg] 2020 Jun; Vol. 138, pp. 672-679.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*diagnostic imaging
Cognitive Dysfunction/*diagnostic imaging
Parkinson Disease/*diagnostic imaging
Aged ; Case-Control Studies ; Cognition ; Cognitive Dysfunction/physiopathology ; Cognitive Dysfunction/psychology ; Female ; Functional Neuroimaging ; Gait Disorders, Neurologic/physiopathology ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Parkinson Disease/physiopathology ; Parkinson Disease/psychology ; Rest ; Tremor/physiopathology
Czasopismo naukowe
Tytuł :
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.
Autorzy :
Bryois J; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Skene NG; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.; UCL Institute of Neurology, Queen Square, London, UK.; Division of Brain Sciences, Department of Medicine, Imperial College, London, UK.; UK Dementia Research Institute at Imperial College, London, UK.
Hansen TF; Danish Headache Center, Dept of Neurology, Copenhagen University Hospital, Glostrup, Denmark.; Institute of Biological Psychiatry, Copenhagen University Hospital MHC Sct Hans, Roskilde, Denmark.; Novo Nordic Foundations Center for Protein Research, Copenhagen University, Copenhagen, Denmark.
Kogelman LJA; Danish Headache Center, Dept of Neurology, Copenhagen University Hospital, Glostrup, Denmark.
Watson HJ; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; School of Psychology, Curtin University, Perth, Western Australia, Australia.; Division of Paediatrics, School of Medicine, The University of Western Australia, Perth, Western Australia, Australia.
Liu Z; Division of Brain Sciences, Department of Medicine, Imperial College, London, UK.; UK Dementia Research Institute at Imperial College, London, UK.
Brueggeman L; Department of Psychiatry, University of Iowa Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Breen G; Institute of Psychiatry, MRC Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK.; National Institute for Health Research Biomedical Research Centre, South London and Maudsley National Health Service Trust, London, UK.
Bulik CM; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Nutrition, University of North Carolina, Chapel Hill, NC, USA.
Arenas E; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Hjerling-Leffler J; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden. .
Sullivan PF; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. .; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA. .
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Corporate Authors :
Eating Disorders Working Group of the Psychiatric Genomics Consortium
International Headache Genetics Consortium
23andMe Research Team
Źródło :
Nature genetics [Nat Genet] 2020 May; Vol. 52 (5), pp. 482-493. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*pathology
Parkinson Disease/*etiology
Parkinson Disease/*genetics
Animals ; Genome-Wide Association Study/methods ; Humans ; Mice ; Neurons/pathology ; Parkinson Disease/pathology ; Transcriptome/genetics
Czasopismo naukowe
Tytuł :
Brain iron deposition is linked with cognitive severity in Parkinson's disease.
Autorzy :
Thomas GEC; Dementia Research Centre, UCL Institute of Neurology, London, UK.
Leyland LA; Dementia Research Centre, UCL Institute of Neurology, London, UK.
Schrag AE; Department of Clinical Neuroscience, UCL Institute of Neurology, London, UK.; Movement Disorders Consortium, University College London, London, UK.
Lees AJ; Reta Lila Institute for Brain Studies, University College London, London, UK.
Acosta-Cabronero J; Tenoke Ltd, Cambridge, UK.
Weil RS; Dementia Research Centre, UCL Institute of Neurology, London, UK .; Wellcome Centre for Human Neuroimaging, University College London, London, UK.
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Źródło :
Journal of neurology, neurosurgery, and psychiatry [J Neurol Neurosurg Psychiatry] 2020 Apr; Vol. 91 (4), pp. 418-425. Date of Electronic Publication: 2020 Feb 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*diagnostic imaging
Cognition Disorders/*diagnostic imaging
Iron/*metabolism
Parkinson Disease/*diagnostic imaging
Aged ; Brain/metabolism ; Brain/pathology ; Cognition Disorders/metabolism ; Cognition Disorders/pathology ; Disease Progression ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Mental Status and Dementia Tests ; Middle Aged ; Parkinson Disease/metabolism ; Parkinson Disease/pathology ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
The function of bacterial HtrA is evolutionally conserved in mammalian HtrA2/Omi.
Autorzy :
Chung HJ; Department of Biomedical Sciences and Institute for Medical Science, Chonbuk National University Medical School, Jeonju, Chonbuk, 54907, South Korea.; Gwangju Center, Korea Basic Science Institute, Gwangju, South Korea.
Jamal MAHM; Department of Biomedical Sciences and Institute for Medical Science, Chonbuk National University Medical School, Jeonju, Chonbuk, 54907, South Korea.; Department of Biotechnology and Genetic Engineering, Islamic University, Kushtia, 7003, Bangladesh.
Hong ST; Department of Biomedical Sciences and Institute for Medical Science, Chonbuk National University Medical School, Jeonju, Chonbuk, 54907, South Korea. .
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Źródło :
Scientific reports [Sci Rep] 2020 Mar 24; Vol. 10 (1), pp. 5284. Date of Electronic Publication: 2020 Mar 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*metabolism
High-Temperature Requirement A Serine Peptidase 2/*metabolism
Neurons/*metabolism
Parkinson Disease/*prevention & control
alpha-Synuclein/*metabolism
Animals ; Animals, Genetically Modified ; Brain/pathology ; Disease Models, Animal ; Drosophila melanogaster ; Female ; High-Temperature Requirement A Serine Peptidase 2/genetics ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Neurons/pathology ; Parkinson Disease/metabolism ; Parkinson Disease/pathology ; alpha-Synuclein/genetics
Czasopismo naukowe
Tytuł :
The neuroprotective effect of fullerenols on a model of Parkinson's disease in Drosophila melanogaster.
Autorzy :
Golomidov I; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre, Kurchatov Institute, Gatchina, Russia.
Bolshakova O; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre, Kurchatov Institute, Gatchina, Russia.
Komissarov A; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre, Kurchatov Institute, Gatchina, Russia.
Sharoyko V; Institute of Chemistry, Saint-Petersburg State University, Saint-Petersburg, Russia.
Slepneva Е; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre, Kurchatov Institute, Gatchina, Russia.
Slobodina A; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre, Kurchatov Institute, Gatchina, Russia.
Latypova E; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre, Kurchatov Institute, Gatchina, Russia.
Zherebyateva O; The Orenburg State Medical University, Orenburg, Russia.
Tennikova T; Institute of Chemistry, Saint-Petersburg State University, Saint-Petersburg, Russia.
Sarantseva S; Petersburg Nuclear Physics Institute Named By B.P. Konstantinov of National Research Centre, Kurchatov Institute, Gatchina, Russia. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Mar 05; Vol. 523 (2), pp. 446-451. Date of Electronic Publication: 2019 Dec 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*drug effects
Drosophila melanogaster/*genetics
Fullerenes/*pharmacology
Neuroprotective Agents/*pharmacology
Parkinson Disease/*drug therapy
Animals ; Animals, Genetically Modified ; Brain/metabolism ; Brain/pathology ; Disease Models, Animal ; Dopamine/metabolism ; Dopaminergic Neurons/drug effects ; Dopaminergic Neurons/pathology ; Humans ; Oxidative Stress/drug effects ; Parkinson Disease/metabolism ; Parkinson Disease/pathology ; alpha-Synuclein/metabolism
Czasopismo naukowe
Tytuł :
Extrastriatal I-FP-CIT SPECT impairment in Parkinson's disease - the PPMI cohort.
Autorzy :
Nicastro N; Department of Psychiatry, University of Cambridge, Cambridge, UK. .; Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospitals, 4, rue G. Perret-Gentil, 1205, Geneva, Switzerland. .
Garibotto V; Department of Nuclear Medicine, Geneva University Hospitals, Geneva, Switzerland.; Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Burkhard PR; Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospitals, 4, rue G. Perret-Gentil, 1205, Geneva, Switzerland.; Faculty of Medicine, University of Geneva, Geneva, Switzerland.
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Źródło :
BMC neurology [BMC Neurol] 2020 May 16; Vol. 20 (1), pp. 192. Date of Electronic Publication: 2020 May 16.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*diagnostic imaging
Parkinson Disease/*diagnostic imaging
Serotonin Plasma Membrane Transport Proteins/*metabolism
Tomography, Emission-Computed, Single-Photon/*methods
Adult ; Aged ; Brain/metabolism ; Case-Control Studies ; Cohort Studies ; Disease Progression ; Female ; Humans ; Image Interpretation, Computer-Assisted/methods ; Iodine Radioisotopes ; Male ; Middle Aged ; Parkinson Disease/metabolism ; Serotonin Plasma Membrane Transport Proteins/analysis ; Tropanes
Czasopismo naukowe
Tytuł :
Abnormalities in the white matter tracts in patients with Parkinson disease and psychosis.
Autorzy :
Lenka A; From the Department of Clinical Neurosciences (A.L.); Department of Neurology (A.L., L.G., R.Y., P.K.P.); Department of Neuroimaging and Interventional Radiology (J.S.); Department of Psychiatry (S.S.A.); Department of Clinical Psychology (S.H.), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India; Symbiosis Center for Medical Image Analysis (M.I., A.S.), Symbiosis Institute of Technology (M.I.), Symbiosis International (Deemed University), Lavale, India; and Department of Neurology (A.L.), MedStar Georgetown University Hospital, Washington, DC.
Ingalhalikar M; From the Department of Clinical Neurosciences (A.L.); Department of Neurology (A.L., L.G., R.Y., P.K.P.); Department of Neuroimaging and Interventional Radiology (J.S.); Department of Psychiatry (S.S.A.); Department of Clinical Psychology (S.H.), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India; Symbiosis Center for Medical Image Analysis (M.I., A.S.), Symbiosis Institute of Technology (M.I.), Symbiosis International (Deemed University), Lavale, India; and Department of Neurology (A.L.), MedStar Georgetown University Hospital, Washington, DC.
Shah A; From the Department of Clinical Neurosciences (A.L.); Department of Neurology (A.L., L.G., R.Y., P.K.P.); Department of Neuroimaging and Interventional Radiology (J.S.); Department of Psychiatry (S.S.A.); Department of Clinical Psychology (S.H.), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India; Symbiosis Center for Medical Image Analysis (M.I., A.S.), Symbiosis Institute of Technology (M.I.), Symbiosis International (Deemed University), Lavale, India; and Department of Neurology (A.L.), MedStar Georgetown University Hospital, Washington, DC.
Saini J; From the Department of Clinical Neurosciences (A.L.); Department of Neurology (A.L., L.G., R.Y., P.K.P.); Department of Neuroimaging and Interventional Radiology (J.S.); Department of Psychiatry (S.S.A.); Department of Clinical Psychology (S.H.), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India; Symbiosis Center for Medical Image Analysis (M.I., A.S.), Symbiosis Institute of Technology (M.I.), Symbiosis International (Deemed University), Lavale, India; and Department of Neurology (A.L.), MedStar Georgetown University Hospital, Washington, DC.
Arumugham SS; From the Department of Clinical Neurosciences (A.L.); Department of Neurology (A.L., L.G., R.Y., P.K.P.); Department of Neuroimaging and Interventional Radiology (J.S.); Department of Psychiatry (S.S.A.); Department of Clinical Psychology (S.H.), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India; Symbiosis Center for Medical Image Analysis (M.I., A.S.), Symbiosis Institute of Technology (M.I.), Symbiosis International (Deemed University), Lavale, India; and Department of Neurology (A.L.), MedStar Georgetown University Hospital, Washington, DC.
Hegde S; From the Department of Clinical Neurosciences (A.L.); Department of Neurology (A.L., L.G., R.Y., P.K.P.); Department of Neuroimaging and Interventional Radiology (J.S.); Department of Psychiatry (S.S.A.); Department of Clinical Psychology (S.H.), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India; Symbiosis Center for Medical Image Analysis (M.I., A.S.), Symbiosis Institute of Technology (M.I.), Symbiosis International (Deemed University), Lavale, India; and Department of Neurology (A.L.), MedStar Georgetown University Hospital, Washington, DC.
George L; From the Department of Clinical Neurosciences (A.L.); Department of Neurology (A.L., L.G., R.Y., P.K.P.); Department of Neuroimaging and Interventional Radiology (J.S.); Department of Psychiatry (S.S.A.); Department of Clinical Psychology (S.H.), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India; Symbiosis Center for Medical Image Analysis (M.I., A.S.), Symbiosis Institute of Technology (M.I.), Symbiosis International (Deemed University), Lavale, India; and Department of Neurology (A.L.), MedStar Georgetown University Hospital, Washington, DC.
Yadav R; From the Department of Clinical Neurosciences (A.L.); Department of Neurology (A.L., L.G., R.Y., P.K.P.); Department of Neuroimaging and Interventional Radiology (J.S.); Department of Psychiatry (S.S.A.); Department of Clinical Psychology (S.H.), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India; Symbiosis Center for Medical Image Analysis (M.I., A.S.), Symbiosis Institute of Technology (M.I.), Symbiosis International (Deemed University), Lavale, India; and Department of Neurology (A.L.), MedStar Georgetown University Hospital, Washington, DC.
Pal PK; From the Department of Clinical Neurosciences (A.L.); Department of Neurology (A.L., L.G., R.Y., P.K.P.); Department of Neuroimaging and Interventional Radiology (J.S.); Department of Psychiatry (S.S.A.); Department of Clinical Psychology (S.H.), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India; Symbiosis Center for Medical Image Analysis (M.I., A.S.), Symbiosis Institute of Technology (M.I.), Symbiosis International (Deemed University), Lavale, India; and Department of Neurology (A.L.), MedStar Georgetown University Hospital, Washington, DC. .
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Źródło :
Neurology [Neurology] 2020 May 05; Vol. 94 (18), pp. e1876-e1884. Date of Electronic Publication: 2020 Apr 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*pathology
Parkinson Disease/*pathology
Psychotic Disorders/*pathology
White Matter/*pathology
Aged ; Cross-Sectional Studies ; Diffusion Tensor Imaging ; Female ; Humans ; Male ; Middle Aged ; Parkinson Disease/complications ; Psychotic Disorders/etiology
Czasopismo naukowe
Tytuł :
Functional MRI Signature of Chronic Pain Relief From Deep Brain Stimulation in Parkinson Disease Patients.
Autorzy :
DiMarzio M; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York.
Rashid T; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York.
Hancu I; GE Global Research Center, Niskayuna, New York.
Fiveland E; GE Global Research Center, Niskayuna, New York.
Prusik J; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York.; Department of Neurosurgery, Albany Medical Center, Albany, New York.
Gillogly M; Department of Neurosurgery, Albany Medical Center, Albany, New York.
Madhavan R; GE Global Research Center, Bangalore, India.
Joel S; GE Global Research Center, Bangalore, India.
Durphy J; Department of Neurology, Albany Medical Center, Albany, New York.
Molho E; Department of Neurology, Albany Medical Center, Albany, New York.
Hanspal E; Department of Neurology, Albany Medical Center, Albany, New York.
Shin D; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York.; Department of Neurology, Albany Medical Center, Albany, New York.
Pilitsis JG; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York.; Department of Neurosurgery, Albany Medical Center, Albany, New York.
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Źródło :
Neurosurgery [Neurosurgery] 2019 Dec 01; Vol. 85 (6), pp. E1043-E1049.
Typ publikacji :
Journal Article
MeSH Terms :
Chronic Pain*/etiology
Chronic Pain*/therapy
Deep Brain Stimulation*
Magnetic Resonance Imaging*
Parkinson Disease*/complications
Parkinson Disease*/diagnostic imaging
Parkinson Disease*/therapy
Brain/*diagnostic imaging
Cohort Studies ; Humans
Czasopismo naukowe
Tytuł :
Long-standing multiple sclerosis neurodegeneration: volumetric magnetic resonance imaging comparison to Parkinson's disease, mild cognitive impairment, Alzheimer's disease, and elderly healthy controls.
Autorzy :
Jakimovski D; Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
Bergsland N; Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA; IRCCS, Fondazione Don Carlo Gnocchi, Milan, Italy.
Dwyer MG; Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
Hagemeier J; Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
Ramasamy DP; Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
Szigeti K; Jacobs Multiple Sclerosis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA.
Guttuso T; Jacobs Multiple Sclerosis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA.
Lichter D; Jacobs Multiple Sclerosis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA.
Hojnacki D; Jacobs Multiple Sclerosis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA; Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA.
Weinstock-Guttman B; Jacobs Multiple Sclerosis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA; Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA.
Benedict RHB; Jacobs Multiple Sclerosis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA; Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA.
Zivadinov R; Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA; Jacobs Multiple Sclerosis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA; Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA; Center for Biomedical Imaging at Clinical Translational Science Institute, University at Buffalo, State University of New York, Buffalo, NY, USA. Electronic address: .
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Źródło :
Neurobiology of aging [Neurobiol Aging] 2020 Jun; Vol. 90, pp. 84-92. Date of Electronic Publication: 2020 Feb 08.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Alzheimer Disease/*diagnostic imaging
Alzheimer Disease/*pathology
Brain/*diagnostic imaging
Brain/*physiology
Healthy Aging/*pathology
Magnetic Resonance Imaging/*methods
Multiple Sclerosis/*diagnostic imaging
Multiple Sclerosis/*pathology
Parkinson Disease/*diagnostic imaging
Parkinson Disease/*pathology
Aged ; Aged, 80 and over ; Atrophy ; Female ; Humans ; Male ; Middle Aged ; Organ Size ; Thalamus/diagnostic imaging ; Thalamus/pathology
Czasopismo naukowe
Tytuł :
Oral Supplements of Ginkgo biloba Extract Alleviate Neuroinflammation, Oxidative Impairments and Neurotoxicity in Rotenone-Induced Parkinsonian Rats.
Autorzy :
Mohammed NA; Department of Zoology, Faculty of Science, Alexandria University, Alexandria, Egypt.
Abdou HM; Department of Zoology, Faculty of Science, Alexandria University, Alexandria, Egypt.
Tass MA; Faculty of Art and Science- Badr, Al-Jabal Al-Gharbi University, Gherian, Libya.
Alfwuaires M; Department of Biological Sciences, Faculty of Science, King Faisal University, Hofuf-31982, Al-Ahsa, Saudi Arabia.
Abdel-Moneim AM; Department of Zoology, Faculty of Science, Alexandria University, Alexandria, Egypt.
Essawy AE; Department of Zoology, Faculty of Science, Alexandria University, Alexandria, Egypt.
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Źródło :
Current pharmaceutical biotechnology [Curr Pharm Biotechnol] 2020; Vol. 21 (12), pp. 1259-1268.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*drug effects
Neuroprotective Agents/*therapeutic use
Neurotoxicity Syndromes/*drug therapy
Oxidative Stress/*drug effects
Parkinson Disease/*drug therapy
Plant Extracts/*therapeutic use
Administration, Oral ; Animals ; Antioxidants/metabolism ; Brain/metabolism ; Brain/pathology ; Cytokines/metabolism ; Dietary Supplements ; Disease Models, Animal ; Dopamine/metabolism ; Dopaminergic Neurons/drug effects ; Dopaminergic Neurons/metabolism ; Dopaminergic Neurons/pathology ; Glutathione/metabolism ; Lipid Peroxidation/drug effects ; Male ; Neuroprotective Agents/administration & dosage ; Neurotoxicity Syndromes/metabolism ; Neurotoxicity Syndromes/pathology ; Parkinson Disease/metabolism ; Parkinson Disease/pathology ; Plant Extracts/administration & dosage ; Random Allocation ; Rats ; Rotenone/toxicity ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Interconnections and Modeling Schemes of Kinesia Paradoxa.
Autorzy :
Banou E; Department of Informatics, Ionian University, Corfu, Greece. .
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Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2020; Vol. 1194, pp. 173-180.
Typ publikacji :
Journal Article
MeSH Terms :
Brain*/physiopathology
Gait Disorders, Neurologic*/etiology
Gait Disorders, Neurologic*/physiopathology
Parkinson Disease*/complications
Parkinson Disease*/physiopathology
Gait ; Humans ; Kinetics ; Range of Motion, Articular
Czasopismo naukowe
Tytuł :
Freezing of gait: understanding the complexity of an enigmatic phenomenon.
Autorzy :
Weiss D; Centre for Neurology, Department for Neurodegenerative Diseases, and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Schoellmann A; Centre for Neurology, Department for Neurodegenerative Diseases, and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Fox MD; Berenson-Allen Center, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical Center, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Bohnen NI; Departments of Radiology and Neurology, University of Michigan, Ann Arbor, MI, USA; Veterans Administration Ann Arbor Healthcare System, Ann Arbor, MI, USA; Morris K. Udall Center of Excellence for Parkinson's Disease Research, University of Michigan, Ann Arbor, MI, USA.
Factor SA; Department of Neurology, Emory School of Medicine, Atlanta, GA, USA.
Nieuwboer A; Neuromotor Rehabilitation Research Group, Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.
Hallett M; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Lewis SJG; Parkinson's Disease Research Clinic, Brain and Mind Centre, University of Sydney, Australia.
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Źródło :
Brain : a journal of neurology [Brain] 2020 Jan 01; Vol. 143 (1), pp. 14-30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Brain/*physiopathology
Gait Disorders, Neurologic/*physiopathology
Parkinson Disease/*physiopathology
Apolipoprotein E4/genetics ; Brain/diagnostic imaging ; Brain Mapping ; Cytochrome P-450 CYP2D6/genetics ; Functional Neuroimaging ; Gait Disorders, Neurologic/diagnostic imaging ; Gait Disorders, Neurologic/genetics ; Glucosylceramidase/genetics ; Humans ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/genetics ; Magnetic Resonance Imaging ; Mutation ; Neural Pathways/physiopathology ; Parkinson Disease/diagnostic imaging ; Parkinson Disease/genetics ; Positron-Emission Tomography ; Receptors, Dopamine D2/genetics ; Tomography, Emission-Computed, Single-Photon
Czasopismo naukowe
Tytuł :
Systemic Exosomal Delivery of shRNA Minicircles Prevents Parkinsonian Pathology.
Autorzy :
Izco M; Laboratory of Molecular Neurobiology, Center for Biomedical Research of La Rioja (CIBIR), Logroño 26006, La Rioja, Spain.
Blesa J; HM CINAC, Hospital Universitario HM Puerta del Sur, Mostoles 28938, Madrid, Spain.
Schleef M; PlasmidFactory GmbH & Co. KG, Bielefeld 33607, Germany.
Schmeer M; PlasmidFactory GmbH & Co. KG, Bielefeld 33607, Germany.
Porcari R; Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, University College London, London NW3 2PF, UK.
Al-Shawi R; Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, University College London, London NW3 2PF, UK; Centre for Biomedical Science, Division of Medicine, University College London, London NW3 2PF, UK.
Ellmerich S; Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, University College London, London NW3 2PF, UK.
de Toro M; Genomics and Bioinformatics Core Facility, Center for Biomedical Research of La Rioja (CIBIR), Logroño 26006, La Rioja, Spain.
Gardiner C; Department of Haematology, University College London, London NW3 2PF, UK.
Seow Y; Molecular Engineering Laboratory, Biomedical Sciences Institutes, A*STAR, Singapore 138668, Singapore.
Reinares-Sebastian A; HM CINAC, Hospital Universitario HM Puerta del Sur, Mostoles 28938, Madrid, Spain.
Forcen R; Laboratory of Molecular Neurobiology, Center for Biomedical Research of La Rioja (CIBIR), Logroño 26006, La Rioja, Spain.
Simons JP; Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, University College London, London NW3 2PF, UK; Centre for Biomedical Science, Division of Medicine, University College London, London NW3 2PF, UK.
Bellotti V; Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, University College London, London NW3 2PF, UK.
Cooper JM; Department of Clinical Neuroscience, Institute of Neurology, University College London, London NW3 2PF, UK.
Alvarez-Erviti L; Laboratory of Molecular Neurobiology, Center for Biomedical Research of La Rioja (CIBIR), Logroño 26006, La Rioja, Spain; Department of Clinical Neuroscience, Institute of Neurology, University College London, London NW3 2PF, UK. Electronic address: .
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Źródło :
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2019 Dec 04; Vol. 27 (12), pp. 2111-2122. Date of Electronic Publication: 2019 Aug 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Drug Delivery Systems*
Brain/*metabolism
Exosomes/*genetics
Parkinson Disease/*therapy
RNA, Small Interfering/*genetics
alpha-Synuclein/*administration & dosage
Animals ; Gene Expression Regulation ; Genetic Therapy ; Humans ; Male ; Mice ; Mice, Inbred C3H ; Mice, Inbred C57BL ; Mice, Transgenic ; Parkinson Disease/genetics ; Parkinson Disease/pathology ; alpha-Synuclein/antagonists & inhibitors ; alpha-Synuclein/genetics
Czasopismo naukowe
Tytuł :
Neural bases of impulse control disorders in Parkinson's disease: A systematic review and an ALE meta-analysis.
Autorzy :
Santangelo G; Department of Psychology, University of Campania 'Luigi Vanvitelli', Caserta, Italy. Electronic address: .
Raimo S; Department of Psychology, University of Campania 'Luigi Vanvitelli', Caserta, Italy; Department of Medical and Surgical Sciences, University of 'Magna Graecia', Catanzaro, Italy; Neuropsychology Unit, I.R.C.C.S. Fondazione Santa Lucia of Rome, Rome, Italy.
Cropano M; Department of Psychology, University of Campania 'Luigi Vanvitelli', Caserta, Italy.
Vitale C; Department of Motor Sciences and Wellness, University 'Parthenope', Naples, Italy.
Barone P; Center for Neurodegenerative Diseases (CEMAND), Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Salerno, Italy.
Trojano L; Department of Psychology, University of Campania 'Luigi Vanvitelli', Caserta, Italy.
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Źródło :
Neuroscience and biobehavioral reviews [Neurosci Biobehav Rev] 2019 Dec; Vol. 107, pp. 672-685. Date of Electronic Publication: 2019 Oct 03.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Brain/*physiopathology
Disruptive, Impulse Control, and Conduct Disorders/*etiology
Parkinson Disease/*complications
Brain/diagnostic imaging ; Disruptive, Impulse Control, and Conduct Disorders/diagnostic imaging ; Disruptive, Impulse Control, and Conduct Disorders/physiopathology ; Functional Neuroimaging ; Humans ; Parkinson Disease/diagnostic imaging ; Parkinson Disease/physiopathology ; Parkinson Disease/psychology
Czasopismo naukowe
Tytuł :
Neuroprotective effects of Suhexiang Wan on the in vitro and in vivo models of Parkinson's disease.
Autorzy :
Liu Q; Department of Oriental Medicine, Dongguk University, Gyeogju, 38066, Republic of Korea.; Department of Oriental Neuropsychiatry, Graduate School of Oriental Medicine, Dongguk University, Gyeonggi-do 10326, Republic of Korea.
Sang Heon K; Department of Oriental Neuropsychiatry, Graduate School of Oriental Medicine, Dongguk University, Gyeonggi-do 10326, Republic of Korea.
Yung-Wei S; Department of Oriental Neuropsychiatry, Graduate School of Oriental Medicine, Dongguk University, Gyeonggi-do 10326, Republic of Korea.
Sok Cheon P; School of Biomedical Sciences, Charles Sturt University, Bathurst, New South Wales, 2795, Australia.
Wonwoong L; College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
Jongki H; College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
Jaehwan J; College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
Kyoung Sang C; Department of Biological Sciences, Konkuk University, Seoul 05029, Republic of Korea.
Songhee J; Department of Biomedical Sciences, Center for Creative Biomedical Scientists at Chonnam National University, Gwangju 61469, Korea.
Byung-Soo K; Department of Oriental Medicine, Dongguk University, Gyeogju, 38066, Republic of Korea.; Department of Oriental Neuropsychiatry, Graduate School of Oriental Medicine, Dongguk University, Gyeonggi-do 10326, Republic of Korea.
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Źródło :
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan [J Tradit Chin Med] 2019 Dec; Vol. 39 (6), pp. 800-808.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*metabolism
Neuroprotective Agents/*therapeutic use
Parkinson Disease/*drug therapy
Animals ; Blotting, Western ; Brain/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Disease Models, Animal ; Drugs, Chinese Herbal/therapeutic use ; Humans ; Immunohistochemistry ; Male ; Mice ; Mice, Inbred ICR ; Mitochondria/drug effects ; Mitochondria/metabolism ; Neuroprotective Agents/metabolism ; Parkinson Disease/metabolism ; Reactive Oxygen Species/metabolism ; Substantia Nigra/drug effects ; Substantia Nigra/metabolism
Czasopismo naukowe
Tytuł :
Brain structural correlates of depressive symptoms in Parkinson's disease patients at different disease stage.
Autorzy :
Li Y; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine 310000, Hangzhou, China; Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University 325000, Wenzhou, China.
Huang P; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine 310000, Hangzhou, China.
Guo T; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine 310000, Hangzhou, China.
Guan X; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine 310000, Hangzhou, China.
Gao T; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine 310000, Hangzhou, China.
Sheng W; Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University 325000, Wenzhou, China.
Zhou C; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine 310000, Hangzhou, China.
Wu J; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine 310000, Hangzhou, China.
Song Z; Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, No.88 Jiefang Road, Shangcheng District, Hangzhou 310009, China.
Xuan M; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine 310000, Hangzhou, China.
Gu Q; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine 310000, Hangzhou, China.
Xu X; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine 310000, Hangzhou, China.
Yang Y; Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University 325000, Wenzhou, China. Electronic address: .
Zhang M; Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine 310000, Hangzhou, China. Electronic address: .
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Źródło :
Psychiatry research. Neuroimaging [Psychiatry Res Neuroimaging] 2020 Feb 29; Vol. 296, pp. 111029. Date of Electronic Publication: 2019 Dec 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*pathology
Depression/*pathology
Parkinson Disease/*pathology
Anisotropy ; Brain/diagnostic imaging ; Depression/diagnostic imaging ; Emotions ; Female ; Gray Matter/pathology ; Humans ; Magnetic Resonance Imaging ; Neuropsychological Tests ; Parkinson Disease/diagnostic imaging ; Temporal Lobe/pathology ; White Matter/pathology
Czasopismo naukowe
Tytuł :
α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model.
Autorzy :
Taguchi T; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ikuno M; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hondo M; International Institute for Integrative Sleep Medicine (WPI-IIIS), The University of Tsukuba, Ibaraki, Japan.
Parajuli LK; Department of Cell Biology and Neuroscience, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Taguchi K; Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Ueda J; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Sawamura M; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Okuda S; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Nakanishi E; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hara J; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Uemura N; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hatanaka Y; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ayaki T; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Matsuzawa S; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Tanaka M; Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
El-Agnaf OMA; Neurological Disorders Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation, Doha, Qatar.
Koike M; Department of Cell Biology and Neuroscience, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Yanagisawa M; International Institute for Integrative Sleep Medicine (WPI-IIIS), The University of Tsukuba, Ibaraki, Japan.
Uemura MT; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yamakado H; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Takahashi R; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
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Źródło :
Brain : a journal of neurology [Brain] 2020 Jan 01; Vol. 143 (1), pp. 249-265.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Mice*
Prodromal Symptoms*
Brain/*metabolism
Olfaction Disorders/*genetics
Parkinson Disease/*genetics
REM Sleep Behavior Disorder/*genetics
alpha-Synuclein/*genetics
Animals ; Cell Count ; Chromosomes, Artificial, Bacterial ; Electroencephalography ; Electromyography ; Endopeptidase K/metabolism ; Mice, Transgenic ; Olfaction Disorders/physiopathology ; Parkinson Disease/physiopathology ; Polymorphism, Single Nucleotide ; REM Sleep Behavior Disorder/physiopathology ; Sleep ; alpha-Synuclein/metabolism
Czasopismo naukowe
Tytuł :
A new avenue for treating Parkinson's disease targeted at aggrephagy modulation and neuroinflammation: Insights from in vitro and animal studies.
Autorzy :
Tikhonova MA; Scientific Research Institute of Physiology and Basic Medicine (SRIPhBM), Novosibirsk, Russia. Electronic address: .
Pokaż więcej
Źródło :
EBioMedicine [EBioMedicine] 2020 Jan; Vol. 51, pp. 102575. Date of Electronic Publication: 2019 Dec 31.
Typ publikacji :
Journal Article
MeSH Terms :
Autophagy*
Protein Aggregates*
Brain/*pathology
Inflammation/*pathology
Parkinson Disease/*therapy
Animals ; Clinical Trials as Topic ; Disease Models, Animal ; Humans ; Mice ; Parkinson Disease/drug therapy ; Pyridones/therapeutic use ; Pyrimidines/therapeutic use ; alpha-Synuclein/metabolism
Czasopismo naukowe

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