Lipidomic QTL in Diversity Outbred mice identifies a novel function for α/β hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin.
Autorzy:
Price TR; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, United States of America. Stapleton DS; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, United States of America. Schueler KL; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, United States of America. Norris MK; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, United States of America. ParksBW; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America. Yandell BS; Department of Statistics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America. Churchill GA; The Jackson Laboratory, Bar Harbor, Maine, United States of America. Holland WL; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, United States of America. Keller MP; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, United States of America. Attie AD; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2023 Jul 31; Vol. 19 (7), pp. e1010713. Date of Electronic Publication: 2023 Jul 31 (Print Publication: 2023).
Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis.
Autorzy:
Norheim F; Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway. Chella Krishnan K; Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. Bjellaas T; Vitas AS, Oslo, Norway. Vergnes L; Department of Human Genetics, University of California at Los Angeles, Los Angeles, CA, USA. Pan C; Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. ParksBW; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA. Meng Y; Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. Lang J; Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. Ward JA; Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. Reue K; Department of Human Genetics, University of California at Los Angeles, Los Angeles, CA, USA. Mehrabian M; Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. Gundersen TE; Vitas AS, Oslo, Norway. Péterfy M; Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.; Depatrment of Basic Medical Sciences, Western University of Health Sciences, Pomona, CA, USA. Dalen KT; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway. Drevon CA; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway.; Vitas AS, Oslo, Norway. Hui ST; Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. Lusis AJ; Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, University of California at Los Angeles, Los Angeles, CA, USA. Seldin MM; Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.; Department of Biological Chemistry and Center for Epigenetics and Metabolism, University of California, Irvine, Irvine, CA, USA.
PGC-1a integrates a metabolism and growth network linked to caloric restriction.
Autorzy:
Miller KN; Division of Geriatrics, Department of Medicine, SMPH, University of Wisconsin, Madison, Wisconsin, USA. Clark JP; Division of Geriatrics, Department of Medicine, SMPH, University of Wisconsin, Madison, Wisconsin, USA. Martin SA; Division of Geriatrics, Department of Medicine, SMPH, University of Wisconsin, Madison, Wisconsin, USA. Howell PR; Division of Geriatrics, Department of Medicine, SMPH, University of Wisconsin, Madison, Wisconsin, USA. Burhans MS; Division of Geriatrics, Department of Medicine, SMPH, University of Wisconsin, Madison, Wisconsin, USA. Haws SA; Department of Biomolecular Chemistry, University of Wisconsin, Madison, Wisconsin, USA.; Wisconsin Institute for Discovery, University of Wisconsin, Madison, Wisconsin, USA. Johnson NB; Division of Geriatrics, Department of Medicine, SMPH, University of Wisconsin, Madison, Wisconsin, USA. Rhoads TW; Division of Geriatrics, Department of Medicine, SMPH, University of Wisconsin, Madison, Wisconsin, USA. Pavelec DM; Biotechnology Center, University of Wisconsin, Madison, Wisconsin, USA. Eliceiri KW; Laboratory for Optical and Computational Instrumentation, University of Wisconsin Madison, Wisconsin, USA. Roopra AS; Department of Neuroscience, University of Wisconsin, Madison, Wisconsin, USA. Ntambi JM; Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, USA.; Department of Nutritional Sciences, University of Wisconsin, Madison, Wisconsin, USA. Denu JM; Department of Biomolecular Chemistry, University of Wisconsin, Madison, Wisconsin, USA.; Wisconsin Institute for Discovery, University of Wisconsin, Madison, Wisconsin, USA.; Morgridge Institute for Research, Madison, Wisconsin, USA. ParksBW; Department of Nutritional Sciences, University of Wisconsin, Madison, Wisconsin, USA. Anderson RM; Division of Geriatrics, Department of Medicine, SMPH, University of Wisconsin, Madison, Wisconsin, USA.; Geriatric Research, Education, and Clinical Center, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, USA.
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Źródło:
Aging cell [Aging Cell] 2019 Oct; Vol. 18 (5), pp. e12999. Date of Electronic Publication: 2019 Jul 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Chromatin variation associated with liver metabolism is mediated by transposable elements.
Autorzy:
Du J; Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, CA USA ; Irell & Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA USA. Leung A; Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, CA USA. Trac C; Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, CA USA. Lee M; Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, CA USA ; Irell & Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA USA. ParksBW; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI USA. Lusis AJ; Department of Medicine, University of California, Los Angeles, CA USA. Natarajan R; Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, CA USA ; Irell & Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA USA. Schones DE; Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, CA USA ; Irell & Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA USA.
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Źródło:
Epigenetics & chromatin [Epigenetics Chromatin] 2016 Jul 08; Vol. 9, pp. 28. Date of Electronic Publication: 2016 Jul 08 (Print Publication: 2016).
Bariatric Surgery Induces Disruption in Inflammatory Signaling Pathways Mediated by Immune Cells in Adipose Tissue: A RNA-Seq Study.
Autorzy:
Poitou C; Institute of Cardiometabolism And Nutrition (ICAN), Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Nutrition Department, F-75013, Paris, France; Sorbonne Universités, University Pierre et Marie Curie (UPMC), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR_S 1166, Nutriomics team, F-75005, Paris, France. Perret C; Institute of Cardiometabolism And Nutrition (ICAN), Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Nutrition Department, F-75013, Paris, France; Sorbonne Universités, University Pierre et Marie Curie (UPMC), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR_S 1166, Genomics and Pathophysiology of Cardiovascular Diseases team, F-75013, Paris, France. Mathieu F; Institute of Cardiometabolism And Nutrition (ICAN), Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Nutrition Department, F-75013, Paris, France; Sorbonne Universités, University Pierre et Marie Curie (UPMC), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR_S 1166, Genomics and Pathophysiology of Cardiovascular Diseases team, F-75013, Paris, France. Truong V; Institute of Cardiometabolism And Nutrition (ICAN), Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Nutrition Department, F-75013, Paris, France; Sorbonne Universités, University Pierre et Marie Curie (UPMC), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR_S 1166, Genomics and Pathophysiology of Cardiovascular Diseases team, F-75013, Paris, France. Blum Y; Department of Medicine/Division of Cardiology, University of California Los Angeles, Los Angeles, California 90095, United States of America. Durand H; Institute of Cardiometabolism And Nutrition (ICAN), Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Nutrition Department, F-75013, Paris, France; Sorbonne Universités, University Pierre et Marie Curie (UPMC), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR_S 1166, Genomics and Pathophysiology of Cardiovascular Diseases team, F-75013, Paris, France. Alili R; Institute of Cardiometabolism And Nutrition (ICAN), Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Nutrition Department, F-75013, Paris, France; Sorbonne Universités, University Pierre et Marie Curie (UPMC), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR_S 1166, Nutriomics team, F-75005, Paris, France. Chelghoum N; Sorbonne Universités, University Pierre et Marie Curie (UPMC), Post-Genomic Platform of Pitié-Salpêtrière (P3S), F-75013, Paris, France. Pelloux V; Institute of Cardiometabolism And Nutrition (ICAN), Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Nutrition Department, F-75013, Paris, France; Sorbonne Universités, University Pierre et Marie Curie (UPMC), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR_S 1166, Nutriomics team, F-75005, Paris, France. Aron-Wisnewsky J; Institute of Cardiometabolism And Nutrition (ICAN), Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Nutrition Department, F-75013, Paris, France; Sorbonne Universités, University Pierre et Marie Curie (UPMC), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR_S 1166, Nutriomics team, F-75005, Paris, France. Torcivia A; Assistance Publique-Hôpitaux de Paris, Department of Visceral Surgery, Pitié-Salpêtrière Hospital, F-75013, Paris, France. Bouillot JL; Assistance Publique-Hôpitaux de Paris, Department of General, Digestive and Metabolic Surgery, Ambroise-Paré Hospital, F- 92100, Boulogne-Billancourt, France. ParksBW; Department of Medicine/Division of Cardiology, University of California Los Angeles, Los Angeles, California 90095, United States of America. Ninio E; Institute of Cardiometabolism And Nutrition (ICAN), Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Nutrition Department, F-75013, Paris, France; Sorbonne Universités, University Pierre et Marie Curie (UPMC), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR_S 1166, Genomics and Pathophysiology of Cardiovascular Diseases team, F-75013, Paris, France. Clément K; Institute of Cardiometabolism And Nutrition (ICAN), Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Nutrition Department, F-75013, Paris, France; Sorbonne Universités, University Pierre et Marie Curie (UPMC), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR_S 1166, Nutriomics team, F-75005, Paris, France. Tiret L; Institute of Cardiometabolism And Nutrition (ICAN), Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Nutrition Department, F-75013, Paris, France; Sorbonne Universités, University Pierre et Marie Curie (UPMC), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR_S 1166, Genomics and Pathophysiology of Cardiovascular Diseases team, F-75013, Paris, France.
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Źródło:
PloS one [PLoS One] 2015 May 04; Vol. 10 (5), pp. e0125718. Date of Electronic Publication: 2015 May 04 (Print Publication: 2015).
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