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Wyświetlanie 1-7 z 7
Tytuł:
Insights into the Genetic Profile of Two Siblings Affected by Unverricht-Lundborg Disease Using Patient-Derived hiPSCs.
Autorzy:
Lucchino V; Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Scaramuzzino L; Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Scalise S; Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Lo Conte M; Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Zannino C; Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Benedetto GL; Department of Medical and Surgical Sciences, University Magna Graecia, 88100 Catanzaro, Italy.
Aguglia U; Department of Medical and Surgical Sciences, University Magna Graecia, 88100 Catanzaro, Italy.
Ferlazzo E; Department of Medical and Surgical Sciences, University Magna Graecia, 88100 Catanzaro, Italy.
Cuda G; Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Parrotta EI; Department of Medical and Surgical Sciences, University Magna Graecia, 88100 Catanzaro, Italy.
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Źródło:
Cells [Cells] 2022 Nov 04; Vol. 11 (21). Date of Electronic Publication: 2022 Nov 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Unverricht-Lundborg Syndrome*/genetics
Humans ; Cystatin B/genetics ; Siblings ; Genetic Profile ; Cathepsins/genetics
Czasopismo naukowe
Tytuł:
In vitro CSC-derived cardiomyocytes exhibit the typical microRNA-mRNA blueprint of endogenous cardiomyocytes.
Autorzy:
Scalise M; Department of Experimental and Clinical Medicine, Magna Graecia University, Catanzaro, Italy.
Marino F; Department of Experimental and Clinical Medicine, Magna Graecia University, Catanzaro, Italy.
Salerno L; Department of Experimental and Clinical Medicine, Magna Graecia University, Catanzaro, Italy.
Mancuso T; Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Cappetta D; Department of Experimental Medicine, University of Campania 'L. Vanvitelli', Naples, Italy.
Barone A; Department of Experimental and Clinical Medicine, Magna Graecia University, Catanzaro, Italy.
Parrotta EI; Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Torella A; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy.
Palumbo D; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Salerno, Italy.; Clinical Research and Innovation, Clinica Montevergine, Mercogliano, Italy.
Veltri P; Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
De Angelis A; Department of Experimental Medicine, University of Campania 'L. Vanvitelli', Naples, Italy.
Berrino L; Department of Experimental Medicine, University of Campania 'L. Vanvitelli', Naples, Italy.
Rossi F; Department of Experimental Medicine, University of Campania 'L. Vanvitelli', Naples, Italy.
Weisz A; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Salerno, Italy.
Rota M; Department of Physiology, New York Medical College, Valhalla, NY, USA.
Urbanek K; Department of Experimental and Clinical Medicine, Magna Graecia University, Catanzaro, Italy.
Nadal-Ginard B; Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Torella D; Department of Experimental and Clinical Medicine, Magna Graecia University, Catanzaro, Italy. .
Cianflone E; Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy. .; Department of Physiology, New York Medical College, Valhalla, NY, USA. .
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Źródło:
Communications biology [Commun Biol] 2021 Sep 30; Vol. 4 (1), pp. 1146. Date of Electronic Publication: 2021 Sep 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation/*genetics
MicroRNAs/*genetics
Myocytes, Cardiac/*metabolism
RNA, Messenger/*genetics
Stem Cells/*metabolism
Animals ; Cell Cycle ; Mice ; MicroRNAs/metabolism ; Muscle Development/genetics ; RNA, Messenger/metabolism ; Transcriptome ; Up-Regulation
Czasopismo naukowe
Tytuł:
Uncovering the Metabolic and Stress Responses of Human Embryonic Stem Cells to FTH1 Gene Silencing.
Autorzy:
Scaramuzzino L; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Lucchino V; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Scalise S; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Lo Conte M; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Zannino C; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Sacco A; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
Biamonte F; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.; Center of Interdepartmental Services (CIS), 'Magna Graecia' University of Catanzaro, 88100 Catanzaro, Italy.
Parrotta EI; Department of Medical and Surgical Sciences, University Magna Graecia, 88100 Catanzaro, Italy.
Costanzo FS; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.; Center of Interdepartmental Services (CIS), 'Magna Graecia' University of Catanzaro, 88100 Catanzaro, Italy.
Cuda G; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, University Magna Graecia, 88100 Catanzaro, Italy.
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Źródło:
Cells [Cells] 2021 Sep 15; Vol. 10 (9). Date of Electronic Publication: 2021 Sep 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Stress*
Ferritins/*genetics
Human Embryonic Stem Cells/*metabolism
NF-E2-Related Factor 2/*metabolism
Oxidoreductases/*genetics
Antioxidant Response Elements ; Apoptosis ; Cell Differentiation ; Cells, Cultured ; Ferritins/pharmacology ; Gene Silencing ; Humans ; Oxidation-Reduction ; Oxidoreductases/metabolism ; Pentose Phosphate Pathway ; Signal Transduction
Czasopismo naukowe
Tytuł:
Deciphering the Role of Wnt and Rho Signaling Pathway in iPSC-Derived ARVC Cardiomyocytes by In Silico Mathematical Modeling.
Autorzy:
Parrotta EI; Department of Medical and Surgical Sciences, Magna Græcia University, 88100 Catanzaro, Italy.
Procopio A; Department of Clinical and Experimental Medicine, Magna Græcia University, 88100 Catanzaro, Italy.
Scalise S; Department of Clinical and Experimental Medicine, Magna Græcia University, 88100 Catanzaro, Italy.
Esposito C; Department of Clinical and Experimental Medicine, Magna Græcia University, 88100 Catanzaro, Italy.
Nicoletta G; Department of Clinical and Experimental Medicine, Magna Græcia University, 88100 Catanzaro, Italy.
Santamaria G; Department of Clinical and Experimental Medicine, Magna Græcia University, 88100 Catanzaro, Italy.; Klinik und Poliklinik Innere Medizin I, Klinikum Rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
De Angelis MT; Department of Clinical and Experimental Medicine, Magna Græcia University, 88100 Catanzaro, Italy.; Klinik und Poliklinik Innere Medizin I, Klinikum Rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
Dorn T; Klinik und Poliklinik Innere Medizin I, Klinikum Rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
Moretti A; Klinik und Poliklinik Innere Medizin I, Klinikum Rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, 80802 Munich, Germany.
Laugwitz KL; Klinik und Poliklinik Innere Medizin I, Klinikum Rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, 80802 Munich, Germany.
Montefusco F; Department of Chemistry and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Cosentino C; Department of Clinical and Experimental Medicine, Magna Græcia University, 88100 Catanzaro, Italy.
Cuda G; Department of Clinical and Experimental Medicine, Magna Græcia University, 88100 Catanzaro, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 18; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 18.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*
Induced Pluripotent Stem Cells/*metabolism
Myocytes, Cardiac/*metabolism
beta Catenin/*metabolism
rho-Associated Kinases/*metabolism
rhoA GTP-Binding Protein/*metabolism
Adipogenesis/genetics ; Algorithms ; Arrhythmogenic Right Ventricular Dysplasia/genetics ; Arrhythmogenic Right Ventricular Dysplasia/metabolism ; Arrhythmogenic Right Ventricular Dysplasia/pathology ; Cells, Cultured ; Computer Simulation ; Gene Expression Regulation ; Humans ; Induced Pluripotent Stem Cells/cytology ; Models, Theoretical ; PPAR gamma/genetics ; PPAR gamma/metabolism ; gamma Catenin/metabolism
Czasopismo naukowe
Tytuł:
Statins Stimulate New Myocyte Formation After Myocardial Infarction by Activating Growth and Differentiation of the Endogenous Cardiac Stem Cells.
Autorzy:
Cianflone E; Department of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Cappetta D; Department of Experimental Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.
Mancuso T; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
Sabatino J; Department of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Marino F; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
Scalise M; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
Albanese M; Department of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Salatino A; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
Parrotta EI; Department of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Cuda G; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
De Angelis A; Department of Experimental Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.
Berrino L; Department of Experimental Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.
Rossi F; Department of Experimental Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.
Nadal-Ginard B; Department of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Torella D; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
Urbanek K; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 26; Vol. 21 (21). Date of Electronic Publication: 2020 Oct 26.
Typ publikacji:
Journal Article
MeSH Terms:
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage
Muscle Cells/*cytology
Myocardial Infarction/*drug therapy
Myocardium/*cytology
Stem Cells/*drug effects
Animals ; Cell Differentiation/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Disease Models, Animal ; Female ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology ; Mice ; Muscle Cells/drug effects ; Muscle Cells/metabolism ; Myocardial Infarction/etiology ; Myocardial Infarction/metabolism ; Myocardium/metabolism ; Phosphorylation/drug effects ; Pravastatin/administration & dosage ; Pravastatin/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rosuvastatin Calcium/administration & dosage ; Rosuvastatin Calcium/pharmacology ; Simvastatin/administration & dosage ; Simvastatin/pharmacology ; Stem Cells/cytology ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł:
Modeling Cardiac Disease Mechanisms Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Progress, Promises and Challenges.
Autorzy:
Parrotta EI; Department of Experimental and Clinical Medicine, Research Center for Advanced Biochemistry and Molecular Biology, University 'Magna Graecia' of Catanzaro, 88100 Loc. Germaneto, Catanzaro, Italy.
Lucchino V; Department of Experimental and Clinical Medicine, Research Center for Advanced Biochemistry and Molecular Biology, University 'Magna Graecia' of Catanzaro, 88100 Loc. Germaneto, Catanzaro, Italy.
Scaramuzzino L; Department of Experimental and Clinical Medicine, Research Center for Advanced Biochemistry and Molecular Biology, University 'Magna Graecia' of Catanzaro, 88100 Loc. Germaneto, Catanzaro, Italy.
Scalise S; Department of Experimental and Clinical Medicine, Research Center for Advanced Biochemistry and Molecular Biology, University 'Magna Graecia' of Catanzaro, 88100 Loc. Germaneto, Catanzaro, Italy.
Cuda G; Department of Experimental and Clinical Medicine, Research Center for Advanced Biochemistry and Molecular Biology, University 'Magna Graecia' of Catanzaro, 88100 Loc. Germaneto, Catanzaro, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Jun 19; Vol. 21 (12). Date of Electronic Publication: 2020 Jun 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Heart Diseases/*pathology
Induced Pluripotent Stem Cells/*cytology
Cell Differentiation ; Disease Progression ; Heart Diseases/metabolism ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Induced Pluripotent Stem Cells/pathology ; Models, Biological ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; Signal Transduction
Czasopismo naukowe
Tytuł:
Stem Cells: The Game Changers of Human Cardiac Disease Modelling and Regenerative Medicine.
Autorzy:
Parrotta EI; Department of Experimental and Clinical Medicine, Research Center for Advanced Biochemistry and Molecular Biology, University 'Magna Graecia' of Catanzaro, 88100 Loc., Germaneto, Catanzaro, Italy.
Scalise S; Department of Experimental and Clinical Medicine, Research Center for Advanced Biochemistry and Molecular Biology, University 'Magna Graecia' of Catanzaro, 88100 Loc., Germaneto, Catanzaro, Italy.
Scaramuzzino L; Department of Experimental and Clinical Medicine, Research Center for Advanced Biochemistry and Molecular Biology, University 'Magna Graecia' of Catanzaro, 88100 Loc., Germaneto, Catanzaro, Italy.
Cuda G; Department of Experimental and Clinical Medicine, Research Center for Advanced Biochemistry and Molecular Biology, University 'Magna Graecia' of Catanzaro, 88100 Loc., Germaneto, Catanzaro, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Nov 16; Vol. 20 (22). Date of Electronic Publication: 2019 Nov 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Regenerative Medicine*
Stem Cell Transplantation*
Heart Diseases/*therapy
Cell Culture Techniques ; Cell- and Tissue-Based Therapy ; Embryonic Stem Cells/cytology ; Embryonic Stem Cells/metabolism ; Humans ; Induced Pluripotent Stem Cells/cytology ; Induced Pluripotent Stem Cells/metabolism ; Pluripotent Stem Cells/cytology ; Pluripotent Stem Cells/metabolism ; Tissue Scaffolds/chemistry
Czasopismo naukowe
    Wyświetlanie 1-7 z 7

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