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Tytuł:
Immediate reuse of patch-clamp pipettes after ultrasonic cleaning.
Autorzy:
Jehasse K; Systems Neurophysiology, Institute of Biology II, RWTH-Aachen University, Aachen, Germany. .
Jouhanneau JS; Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; Neuroscience Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Wetz S; Systems Neurophysiology, Institute of Biology II, RWTH-Aachen University, Aachen, Germany.; Research Training Group 2610 InnoRetVision, RWTH-Aachen University, Aachen, Germany.
Schwedt A; Central Facility for Electron Microscopy, RWTH-Aachen University, Aachen, Germany.
Poulet JFA; Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; Neuroscience Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Neumann-Raizel P; Luigs & Neumann GmbH, Ratingen, Germany.
Kampa BM; Systems Neurophysiology, Institute of Biology II, RWTH-Aachen University, Aachen, Germany. .; JARA BRAIN, Institute of Neuroscience and Medicine (INM-10), Forschungszentrum Jülich, Jülich, Germany. .; Research Training Group 2610 InnoRetVision, RWTH-Aachen University, Aachen, Germany. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 18; Vol. 14 (1), pp. 1660. Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Ultrasonics*
Detergents*
Neurons/physiology ; Neurophysiology ; Patch-Clamp Techniques
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MnO2 Nanoflower Integrated Optoelectronic Biointerfaces for Photostimulation of Neurons.
Autorzy:
Kaya, Lokman (AUTHOR)
Karatum, Onuralp (AUTHOR)
Balamur, Rıdvan (AUTHOR)
Kaleli, Hümeyra Nur (AUTHOR)
Önal, Asım (AUTHOR)
Vanalakar, Sharadrao Anandrao (AUTHOR)
Hasanreisoğlu, Murat (AUTHOR)
Nizamoglu, Sedat (AUTHOR)
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Źródło:
Advanced Science. 9/5/2023, Vol. 10 Issue 25, p1-11. 11p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex.
Autorzy:
Lee BR; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Dalley R; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Miller JA; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Chartrand T; Allen Institute for Brain Science, Seattle, WA 98109, USA.; Allen Institute for Neural Dynamics, Seattle, WA 98109, USA.
Close J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Mann R; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Mukora A; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Ng L; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Alfiler L; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Baker K; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Bertagnolli D; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Brouner K; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Casper T; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Csajbok E; MTA-SZTE Research Group for Cortical Microcircuits, Department of Physiology, Anatomy, and Neuroscience, University of Szeged, 6726 Szeged, Hungary.
Donadio N; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Driessens SLW; Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research (CNCR), Vrije Universiteit, Amsterdam, 1081 HV, Netherlands.
Egdorf T; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Enstrom R; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Galakhova AA; Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research (CNCR), Vrije Universiteit, Amsterdam, 1081 HV, Netherlands.
Gary A; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Gelfand E; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Goldy J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Hadley K; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Heistek TS; Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research (CNCR), Vrije Universiteit, Amsterdam, 1081 HV, Netherlands.
Hill D; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Hou WH; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.
Johansen N; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Jorstad N; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Kim L; Allen Institute for Brain Science, Seattle, WA 98109, USA.; Allen Institute for Neural Dynamics, Seattle, WA 98109, USA.
Kocsis AK; MTA-SZTE Research Group for Cortical Microcircuits, Department of Physiology, Anatomy, and Neuroscience, University of Szeged, 6726 Szeged, Hungary.
Kruse L; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Kunst M; Allen Institute for Brain Science, Seattle, WA 98109, USA.
León G; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Long B; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Mallory M; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Maxwell M; Allen Institute for Brain Science, Seattle, WA 98109, USA.
McGraw M; Allen Institute for Brain Science, Seattle, WA 98109, USA.
McMillen D; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Melief EJ; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA.
Molnar G; MTA-SZTE Research Group for Cortical Microcircuits, Department of Physiology, Anatomy, and Neuroscience, University of Szeged, 6726 Szeged, Hungary.
Mortrud MT; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Newman D; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Nyhus J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Opitz-Araya X; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Ozsvár A; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.
Pham T; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Pom A; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Potekhina L; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Rajanbabu R; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Ruiz A; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Sunkin SM; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Szöts I; MTA-SZTE Research Group for Cortical Microcircuits, Department of Physiology, Anatomy, and Neuroscience, University of Szeged, 6726 Szeged, Hungary.
Taskin N; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Thyagarajan B; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Tieu M; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Trinh J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Vargas S; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Vumbaco D; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Waleboer F; Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research (CNCR), Vrije Universiteit, Amsterdam, 1081 HV, Netherlands.
Walling-Bell S; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Weed N; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Williams G; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Wilson J; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Yao S; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Zhou T; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Barzó P; Department of Neurosurgery, University of Szeged, 6725 Szeged, Hungary.
Bakken T; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Cobbs C; Swedish Neuroscience Institute, Seattle, WA 98122, USA.
Dee N; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Ellenbogen RG; Department of Neurological Surgery, University of Washington, Seattle, WA 98195, USA.
Esposito L; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Ferreira M; Department of Neurological Surgery, University of Washington, Seattle, WA 98195, USA.
Gouwens NW; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Grannan B; Department of Neurological Surgery, University of Washington, Seattle, WA 98195, USA.
Gwinn RP; Swedish Neuroscience Institute, Seattle, WA 98122, USA.
Hauptman JS; Department of Neurological Surgery, University of Washington, Seattle, WA 98195, USA.
Hodge R; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Jarsky T; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Keene CD; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA.
Ko AL; Department of Neurological Surgery, University of Washington, Seattle, WA 98195, USA.
Korshoej AR; Department of Neurosurgery, Aarhus University Hospital, 8200 Aarhus, Denmark.
Levi BP; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Meier K; Department of Neurosurgery, Aarhus University Hospital, 8200 Aarhus, Denmark.; Department of Anesthesiology, Aarhus University Hospital, 8200 Aarhus, Denmark.
Ojemann JG; Department of Neurological Surgery, University of Washington, Seattle, WA 98195, USA.
Patel A; Department of Neurological Surgery, University of Washington, Seattle, WA 98195, USA.
Ruzevick J; Department of Neurological Surgery, University of Washington, Seattle, WA 98195, USA.
Silbergeld DL; Department of Neurological Surgery, University of Washington, Seattle, WA 98195, USA.
Smith K; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Sørensen JC; Department of Neurosurgery, Aarhus University Hospital, 8200 Aarhus, Denmark.; Center for Experimental Neuroscience, Aarhus University Hospital, 8200 Aarhus, Denmark.
Waters J; Allen Institute for Brain Science, Seattle, WA 98109, USA.; Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, USA.
Zeng H; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Berg J; Allen Institute for Brain Science, Seattle, WA 98109, USA.; Allen Institute for Neural Dynamics, Seattle, WA 98109, USA.
Capogna M; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.
Goriounova NA; Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research (CNCR), Vrije Universiteit, Amsterdam, 1081 HV, Netherlands.
Kalmbach B; Allen Institute for Brain Science, Seattle, WA 98109, USA.; Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, USA.
de Kock CPJ; Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research (CNCR), Vrije Universiteit, Amsterdam, 1081 HV, Netherlands.
Mansvelder HD; Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research (CNCR), Vrije Universiteit, Amsterdam, 1081 HV, Netherlands.
Sorensen SA; Allen Institute for Brain Science, Seattle, WA 98109, USA.
Tamas G; MTA-SZTE Research Group for Cortical Microcircuits, Department of Physiology, Anatomy, and Neuroscience, University of Szeged, 6726 Szeged, Hungary.
Lein ES; Allen Institute for Brain Science, Seattle, WA 98109, USA.; Department of Neurological Surgery, University of Washington, Seattle, WA 98195, USA.
Ting JT; Allen Institute for Brain Science, Seattle, WA 98109, USA.; Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Oct 13; Vol. 382 (6667), pp. eadf6484. Date of Electronic Publication: 2023 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
GABAergic Neurons*/metabolism
Interneurons*/metabolism
Neocortex*/cytology
Neocortex*/metabolism
Animals ; Humans ; Mice ; Electrophysiological Phenomena ; gamma-Aminobutyric Acid/metabolism ; Patch-Clamp Techniques
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficient sampling-based Bayesian Active Learning for synaptic characterization.
Autorzy:
Gontier C; Department of Physiology, University of Bern, Bern, Switzerland.; Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Surace SC; Department of Physiology, University of Bern, Bern, Switzerland.
Delvendahl I; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich, Zurich, Switzerland.
Müller M; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich, Zurich, Switzerland.; University Research Priority Program (URPP), Adaptive Brain Circuits in Development and Learning (AdaBD), University of Zurich, Zurich, Switzerland.
Pfister JP; Department of Physiology, University of Bern, Bern, Switzerland.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2023 Aug 21; Vol. 19 (8), pp. e1011342. Date of Electronic Publication: 2023 Aug 21 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Problem-Based Learning*
Research Design*
Bayes Theorem ; Action Potentials ; Patch-Clamp Techniques
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Biocytin-Labeling in Whole-Cell Recording: Electrophysiological and Morphological Properties of Pyramidal Neurons in CYLD-Deficient Mice.
Autorzy:
Tan S; School of Life Sciences, Guangzhou University, Guangzhou 510006, China.; School of Life Sciences, South China Normal University, Guangzhou 510631, China.
Mo X; School of Life Sciences, Guangzhou University, Guangzhou 510006, China.
Qin H; School of Life Sciences, Guangzhou University, Guangzhou 510006, China.
Dong B; School of Life Sciences, South China Normal University, Guangzhou 510631, China.
Zhou J; School of Life Sciences, Guangzhou University, Guangzhou 510006, China.
Long C; School of Life Sciences, South China Normal University, Guangzhou 510631, China.
Yang L; School of Life Sciences, Guangzhou University, Guangzhou 510006, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 15; Vol. 28 (10). Date of Electronic Publication: 2023 May 15.
Typ publikacji:
Journal Article
MeSH Terms:
Lysine*
Neurons*
Animals ; Mice ; Patch-Clamp Techniques ; Pyramidal Cells/physiology ; Deubiquitinating Enzyme CYLD
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of patchclamp recordings: model-free multiscale methods and software.
Autorzy:
Pein F; Statistical Laboratory, DPMMS, University of Cambridge, Cambridge, UK. .
Eltzner B; Institute for Mathematical Stochastics, Georg-August-University of Goettingen, Göttingen, Germany.
Munk A; Institute for Mathematical Stochastics, Georg-August-University of Goettingen, Göttingen, Germany.; Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Felix Bernstein Institute for Mathematical Statistics in the Biosciences, Göttingen, Germany.
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Źródło:
European biophysics journal : EBJ [Eur Biophys J] 2021 Mar; Vol. 50 (2), pp. 187-209. Date of Electronic Publication: 2021 Apr 09.
Typ publikacji:
Journal Article
MeSH Terms:
Patch-Clamp Techniques*
Software*
Algorithms ; Ion Channels ; Kinetics ; Markov Chains
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Vivo Whole-Cell Patch-Clamp Methods: Recent Technical Progress and Future Perspectives.
Autorzy:
Noguchi A; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan.
Ikegaya Y; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan.; Institute for AI and Beyond, The University of Tokyo, Tokyo 113-0033, Japan.; Center for Information and Neural Networks, National Institute of Information and Communications Technology, Suita City, Osaka 565-0871, Japan.
Matsumoto N; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan.
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Źródło:
Sensors (Basel, Switzerland) [Sensors (Basel)] 2021 Feb 19; Vol. 21 (4). Date of Electronic Publication: 2021 Feb 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Hippocampus*
Neurons*
Patch-Clamp Techniques*
Action Potentials ; Animals ; Membrane Potentials
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Pharmacologic antagonism of CB1 receptors improves electrophysiological alterations in Purkinje cells exposed to 3-AP.
Autorzy:
Ranjbar H; Neuroscience Research Center, Neuropharmacology Institute, Kerman University of Medical Sciences, Kerman, 76198-13159, Iran.
Soti M; Neuroscience Research Center, Neuropharmacology Institute, Kerman University of Medical Sciences, Kerman, 76198-13159, Iran.
Kohlmeier KA; Department of Drug Design and Pharmacology, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
Janahmadi M; Department of Physiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shabani M; Neuroscience Research Center, Neuropharmacology Institute, Kerman University of Medical Sciences, Kerman, 76198-13159, Iran. .
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Źródło:
BMC neuroscience [BMC Neurosci] 2023 Mar 03; Vol. 24 (1), pp. 18. Date of Electronic Publication: 2023 Mar 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Purkinje Cells*
Brain*
Action Potentials ; Cannabinoid Receptor Antagonists ; Patch-Clamp Techniques ; Receptor, Cannabinoid, CB1
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Application of Machine-Learning Methods to Recognize mitoBK Channels from Different Cell Types Based on the Experimental Patch-Clamp Results.
Autorzy:
Richter-Laskowska M; Institute of Physics, University of Silesia in Katowice, 40-007 Katowice, Poland.
Trybek P; Faculty of Science and Technology, University of Silesia in Katowice, 41-500 Chorzow, Poland.
Bednarczyk P; Department of Physics and Biophysics, Institute of Biology, Warsaw University of Life Sciences-SGGW, 02-787 Warszawa, Poland.
Wawrzkiewicz-Jałowiecka A; Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology, 44-100 Gliwice, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 15; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 15.
Typ publikacji:
Journal Article
MeSH Terms:
Machine Learning*
Patch-Clamp Techniques*
Large-Conductance Calcium-Activated Potassium Channels/*metabolism
Algorithms ; Animals ; Artificial Intelligence ; Endothelium/metabolism ; Female ; Fibroblasts/metabolism ; Hippocampus/metabolism ; Ion Channel Gating ; Kinetics ; Mitochondria/metabolism ; Neural Networks, Computer ; Potassium Channels/metabolism ; Pregnancy ; Pregnancy, Animal ; Protein Conformation ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibitory Effects of Nobiletin on Voltage-Gated Na Channel in Rat Ventricular Myocytes Based on Electrophysiological Analysis and Molecular Docking Method.
Autorzy:
Gu Y; Department of Pharmacology, School of Medicine, Yangzhou University, Yangzhou 225009, China.
Wang J; Department of Pharmacology, School of Medicine, Yangzhou University, Yangzhou 225009, China.
Li M; Department of Pharmacology, School of Medicine, Yangzhou University, Yangzhou 225009, China.
Zhong F; Department of Pharmacology, School of Medicine, Yangzhou University, Yangzhou 225009, China.
Xiang J; Department of Pharmacology, School of Medicine, Yangzhou University, Yangzhou 225009, China.
Xu Z; Department of Pharmacology, School of Medicine, Yangzhou University, Yangzhou 225009, China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China.; Jingsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou 225001, China.; Jiangsu Key Laboratory of Experimental & Translational Non-Coding RNA Research, Yangzhou 225009, China.; Yeda Institute of Gene and Cell Therapy, Taizhou 318000, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 02; Vol. 23 (23). Date of Electronic Publication: 2022 Dec 02.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Arrhythmia Agents*/pharmacology
Myocytes, Cardiac*/metabolism
Animals ; Rats ; Aconitine/metabolism ; Arrhythmias, Cardiac/metabolism ; Molecular Docking Simulation ; Patch-Clamp Techniques ; Sodium/metabolism ; Sodium Channels/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The dependence of acetylcholine on dynamic changes in the membrane potential and an action potential during spike timing-dependent plasticity induction in the hippocampus.
Autorzy:
Sugisaki E; Brain Science Institute, Tamagawa University, Tokyo, Japan.
Fukushima Y; Brain Science Institute, Tamagawa University, Tokyo, Japan.; Kawasaki University of Medical Welfare, Okayama, Japan.
Nakajima N; Graduated School of Engineering, Tamagawa University, Tokyo, Japan.
Aihara T; Brain Science Institute, Tamagawa University, Tokyo, Japan.
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2022 Dec; Vol. 56 (11), pp. 5972-5986. Date of Electronic Publication: 2022 Oct 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcholine*
Neurons*/physiology
Action Potentials/physiology ; Membrane Potentials ; Patch-Clamp Techniques ; Picrotoxin/pharmacology ; Hippocampus/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An in vitro whole-cell electrophysiology dataset of human cortical neurons.
Autorzy:
Howard D; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, M5T 1R8, Canada.
Chameh HM; Krembil Brain Institute, University Health Network, Toronto, ON, M5T 1M8, Canada.
Guet-McCreight A; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, M5T 1R8, Canada.
Hsiao HA; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, M5T 1R8, Canada.
Vuong M; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, M5T 1R8, Canada.
Seo YS; Krembil Brain Institute, University Health Network, Toronto, ON, M5T 1M8, Canada.
Shah P; Krembil Brain Institute, University Health Network, Toronto, ON, M5T 1M8, Canada.
Nigam A; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, M5T 1R8, Canada.; Institute of Medical Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, M5S 1A8, Canada.
Chen Y; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, M5T 1R8, Canada.
Davie M; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, M5T 1R8, Canada.
Hay E; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, M5T 1R8, Canada.; Institute of Medical Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, M5S 1A8, Canada.
Valiante TA; Krembil Brain Institute, University Health Network, Toronto, ON, M5T 1M8, Canada.; Institute of Medical Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, M5S 1A8, Canada.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, M5S 1A4, Canada.; Department of Surgery, Division of Neurosurgery, University of Toronto, Toronto, ON, M5T 1P5, Canada.; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, M5S 3G9, Canada.; Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, M5S 3G8, Canada.; Max Planck-University of Toronto Center for Neural Science and Technology, Toronto, ON, M5S 1A4, Canada.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON , M5S 1A4, Canada.
Tripathy SJ; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, M5T 1R8, Canada.; Institute of Medical Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, M5S 1A8, Canada.; Department of Surgery, Division of Neurosurgery, University of Toronto, Toronto, ON, M5T 1P5, Canada.; Department of Psychiatry, University of Toront, Toronto, ON, M5T 1R8, Canada.
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Źródło:
GigaScience [Gigascience] 2022 Nov 15; Vol. 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Neurons*/physiology
Humans ; Male ; Female ; Mice ; Animals ; Young Adult ; Adult ; Middle Aged ; Patch-Clamp Techniques ; Electrophysiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Studying Synaptic Connectivity and Strength with Optogenetics and Patch-Clamp Electrophysiology.
Autorzy:
Linders, Louisa E. (AUTHOR)
Supiot, Laura. F. (AUTHOR)
Du, Wenjie (AUTHOR)
D'Angelo, Roberto (AUTHOR)
Adan, Roger A. H. (AUTHOR)
Riga, Danai (AUTHOR)
Meye, Frank J. (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Oct2022, Vol. 23 Issue 19, p11612. 31p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Deep-Channel uses deep neural networks to detect single-molecule events from patch-clamp data.
Autorzy:
Celik N; Faculty of Health and Life Science, University of Liverpool, Liverpool, UK.
O'Brien F; Faculty of Health and Life Science, University of Liverpool, Liverpool, UK.
Brennan S; Faculty of Health and Life Science, University of Liverpool, Liverpool, UK.
Rainbow RD; Faculty of Health and Life Science, University of Liverpool, Liverpool, UK.
Dart C; Faculty of Health and Life Science, University of Liverpool, Liverpool, UK.
Zheng Y; Faculty of Health and Life Science, University of Liverpool, Liverpool, UK.
Coenen F; Department of Computer Science, University of Liverpool, Liverpool, UK.
Barrett-Jolley R; Faculty of Health and Life Science, University of Liverpool, Liverpool, UK. .
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Źródło:
Communications biology [Commun Biol] 2020 Jan 07; Vol. 3 (1), pp. 3. Date of Electronic Publication: 2020 Jan 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Electrophysiological Phenomena*
Ion Channel Gating*
Neural Networks, Computer*
Patch-Clamp Techniques*
Single Molecule Imaging*/methods
Ion Channels/*metabolism
Artificial Intelligence ; Humans ; Models, Biological ; ROC Curve ; Supervised Machine Learning ; Workflow
Czasopismo naukowe
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Tytuł:
Block of Voltage-Gated Sodium Channels by Aripiprazole in a State-Dependent Manner.
Autorzy:
Föhr KJ; Department of Anesthesiology and Intensive Care Medicine, University Hospital Ulm, 89081 Ulm, Germany.
Rapp M; Department of Anesthesiology and Intensive Care Medicine, University Hospital Ulm, 89081 Ulm, Germany.
Fauler M; Institute of General Physiology, University of Ulm, 89081 Ulm, Germany.
Zimmer T; Institute of Physiology, University Hospital of Jena, 07747 Jena, Germany.
Jungwirth B; Department of Anesthesiology and Intensive Care Medicine, University Hospital Ulm, 89081 Ulm, Germany.
Messerer DAC; Department of Anesthesiology and Intensive Care Medicine, University Hospital Ulm, 89081 Ulm, Germany.; Department of Transfusion Medicine and Hemostaseology, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, 91052 Erlangen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 25; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 25.
Typ publikacji:
Journal Article
MeSH Terms:
Voltage-Gated Sodium Channels*
Humans ; Aripiprazole/pharmacology ; Kinetics ; Patch-Clamp Techniques ; Myocardium ; Sodium Channel Blockers/pharmacology
Czasopismo naukowe
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Tytuł:
De novo Y1460C missense variant in Na V 1.1 impedes the pore region and results in epileptic encephalopathy.
Autorzy:
Plumereau Q; CERVO Brain Research Center, 2601, de la Canardière, Quebec City, QC, G1J 2G3, Canada.
Ebdalla A; Department of Medical Genetics, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Poulin H; CERVO Brain Research Center, 2601, de la Canardière, Quebec City, QC, G1J 2G3, Canada.
Appendino JP; Department of Medical Genetics, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Scantlebury MH; Neurology Section, Department of Pediatrics, Alberta Children's Hospital, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Au PYB; Neurology Section, Department of Pediatrics, Alberta Children's Hospital, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Chahine M; CERVO Brain Research Center, 2601, de la Canardière, Quebec City, QC, G1J 2G3, Canada. .; Department of Medicine, Faculty of Medicine, Université Laval, Quebec City, QC, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2022 Oct 13; Vol. 12 (1), pp. 17182. Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epilepsy*/genetics
Epilepsy, Generalized*
Action Potentials/physiology ; HEK293 Cells ; Humans ; NAV1.1 Voltage-Gated Sodium Channel/genetics ; NAV1.6 Voltage-Gated Sodium Channel/genetics ; NAV1.6 Voltage-Gated Sodium Channel/metabolism ; Patch-Clamp Techniques ; Seizures ; gamma-Aminobutyric Acid
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Activation of TREK1 Channel in the Anterior Cingulate Cortex Improves Neuropathic Pain in a Rat Model.
Autorzy:
Peng Y; Department of Anesthesiology and SICU, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China.
Zhang Q; Department of Anesthesiology and SICU, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China.
Cheng H; Department of Cardiovascular Surgery, Changhai Hospital, the Navy Medical University, Shanghai 200433, China.
Shen S; Department of Anesthesiology and SICU, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China.
Weng X; Department of Anesthesiology and SICU, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China.
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Źródło:
Computational intelligence and neuroscience [Comput Intell Neurosci] 2022 Sep 30; Vol. 2022, pp. 1372823. Date of Electronic Publication: 2022 Sep 30 (Print Publication: 2022).
Typ publikacji:
Journal Article; Retracted Publication
MeSH Terms:
Gyrus Cinguli*/metabolism
Neuralgia*/metabolism
Animals ; Patch-Clamp Techniques ; Rats ; Rats, Sprague-Dawley ; Sciatic Nerve/injuries ; Sciatic Nerve/metabolism
Czasopismo naukowe
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Tytuł:
A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes.
Autorzy:
Seibertz F; Institute of Pharmacology and Toxicology, University Medical Center Göttingen, Georg-August University Göttingen, Göttingen, Germany.; DZHK (German Center for Cardiovascular Research) partner site Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), Georg-August University Göttingen, Göttingen, Germany.
Rapedius M; Nanion Technologies GmbH, Munich, Germany. .
Fakuade FE; Institute of Pharmacology and Toxicology, University Medical Center Göttingen, Georg-August University Göttingen, Göttingen, Germany.; DZHK (German Center for Cardiovascular Research) partner site Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), Georg-August University Göttingen, Göttingen, Germany.
Tomsits P; Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.; Institute of Surgical Research at the Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, Munich, Germany.; DZHK (German Centre for Cardiovascular Research) Partner Site Munich, Munich Heart Alliance (MHA), Munich, Germany.; Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer (ICONLMU), LMU Munich, Munich, Germany.
Liutkute A; Institute of Pharmacology and Toxicology, University Medical Center Göttingen, Georg-August University Göttingen, Göttingen, Germany.; DZHK (German Center for Cardiovascular Research) partner site Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), Georg-August University Göttingen, Göttingen, Germany.
Cyganek L; DZHK (German Center for Cardiovascular Research) partner site Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), Georg-August University Göttingen, Göttingen, Germany.; Stem Cell Unit, Clinic for Cardiology and Pneumology, University Medical Center Göttingen, Georg-August University Göttingen, Gottingen, Germany.
Becker N; Nanion Technologies GmbH, Munich, Germany.
Majumder R; DZHK (German Center for Cardiovascular Research) partner site Göttingen, Göttingen, Germany.; Biomedical Physics Group, Max Planck Institute for Dynamics and Self Organisation, Gottingen, Germany.
Clauß S; Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.; Institute of Surgical Research at the Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, Munich, Germany.; DZHK (German Centre for Cardiovascular Research) Partner Site Munich, Munich Heart Alliance (MHA), Munich, Germany.; Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer (ICONLMU), LMU Munich, Munich, Germany.
Fertig N; Nanion Technologies GmbH, Munich, Germany. .
Voigt N; Institute of Pharmacology and Toxicology, University Medical Center Göttingen, Georg-August University Göttingen, Göttingen, Germany. .; DZHK (German Center for Cardiovascular Research) partner site Göttingen, Göttingen, Germany. .; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), Georg-August University Göttingen, Göttingen, Germany. .
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Źródło:
Communications biology [Commun Biol] 2022 Sep 15; Vol. 5 (1), pp. 969. Date of Electronic Publication: 2022 Sep 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium*
Myocytes, Cardiac*
Animals ; Electrophysiological Phenomena ; Electrophysiology ; Humans ; Mammals ; Patch-Clamp Techniques ; Swine
Czasopismo naukowe
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Wyświetlanie 1-20 z 6436

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