A mutation in transmembrane protein 135 impairs lipid metabolism in mouse eyecups.
Autorzy:
Landowski M; Department of Medical Genetics, University of Wisconsin-Madison, Madison, WI, USA.; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA. Bhute VJ; Department of Medical Genetics, University of Wisconsin-Madison, Madison, WI, USA.; Department of Chemical Engineering, Imperial College London, South Kensington, London, SW7 2AZ, UK. Takimoto T; Department of Medical Genetics, University of Wisconsin-Madison, Madison, WI, USA. Grindel S; Department of Medical Genetics, University of Wisconsin-Madison, Madison, WI, USA. Shahi PK; Department of Medical Genetics, University of Wisconsin-Madison, Madison, WI, USA.; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA.; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, USA. PattnaikBR; Department of Medical Genetics, University of Wisconsin-Madison, Madison, WI, USA.; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA.; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, USA. Ikeda S; Department of Medical Genetics, University of Wisconsin-Madison, Madison, WI, USA.; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA. Ikeda A; Department of Medical Genetics, University of Wisconsin-Madison, Madison, WI, USA. .; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 14; Vol. 12 (1), pp. 756. Date of Electronic Publication: 2022 Jan 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
The Natural Product β-Escin Targets Cancer and Stromal Cells of the Tumor Microenvironment to Inhibit Ovarian Cancer Metastasis.
Autorzy:
Kenny HA; Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, University of Chicago, Chicago, IL 60637, USA. Hart PC; Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, University of Chicago, Chicago, IL 60637, USA. Kordylewicz K; Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, University of Chicago, Chicago, IL 60637, USA. Lal M; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), NIH, Rockville, MD 20852, USA. Shen M; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), NIH, Rockville, MD 20852, USA. Kara B; Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, University of Chicago, Chicago, IL 60637, USA. Chen YJ; Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, University of Chicago, Chicago, IL 60637, USA. Grassl N; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany. Alharbi Y; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI 53792, USA. PattnaikBR; Department of Pediatrics and Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA. Watters KM; Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, University of Chicago, Chicago, IL 60637, USA. Patankar MS; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI 53792, USA. Ferrer M; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), NIH, Rockville, MD 20852, USA. Lengyel E; Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, University of Chicago, Chicago, IL 60637, USA.
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Źródło:
Cancers [Cancers (Basel)] 2021 Aug 04; Vol. 13 (16). Date of Electronic Publication: 2021 Aug 04.
Hypoxic-ischemic injury causes functional and structural neurovascular degeneration in the juvenile mouse retina.
Autorzy:
Zaitoun IS; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, WIMR 9418, Madison, WI, 53705, USA. .; McPherson Eye Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. . Shahi PK; McPherson Eye Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. Suscha A; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, WIMR 9418, Madison, WI, 53705, USA. Chan K; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, WIMR 9418, Madison, WI, 53705, USA.; McPherson Eye Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. McLellan GJ; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, WIMR 9418, Madison, WI, 53705, USA.; McPherson Eye Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.; Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA. PattnaikBR; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, WIMR 9418, Madison, WI, 53705, USA.; McPherson Eye Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. Sorenson CM; McPherson Eye Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. Sheibani N; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, WIMR 9418, Madison, WI, 53705, USA.; McPherson Eye Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
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Źródło:
Scientific reports [Sci Rep] 2021 Jun 16; Vol. 11 (1), pp. 12670. Date of Electronic Publication: 2021 Jun 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Adhatoda Vasica attenuates inflammatory and hypoxic responses in preclinical mouse models: potential for repurposing in COVID-19-like conditions.
Autorzy:
Gheware A; Genomics and Molecular Medicine, Council of Scientific and Industrial Research -Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, 110007, India.; CSIR's Ayurgenomics Unit-TRISUTRA (Translational Research and Innovative Science ThRoughAyurgenomics) CSIR-IGIB, Delhi, 110007, India.; Centre of Excellence for Applied Development of Ayurveda, Prakriti and Genomics, CSIR's Ayurgenomics Unit-TRISUTRA (Translational Research and Innovative Science ThRoughAyurgenomics), CSIR- IGIB, Delhi, 110007, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Dholakia D; Genomics and Molecular Medicine, Council of Scientific and Industrial Research -Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, 110007, India.; Centre of Excellence for Applied Development of Ayurveda, Prakriti and Genomics, CSIR's Ayurgenomics Unit-TRISUTRA (Translational Research and Innovative Science ThRoughAyurgenomics), CSIR- IGIB, Delhi, 110007, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Kannan S; Center for High Computing, CSIR- Central Leather Research Institute (CLRI), Chennai, 600020, India. Panda L; Center for Translational Research in Lung Disease, CSIR- IGIB, Delhi, 110007, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Rani R; Genomics and Molecular Medicine, Council of Scientific and Industrial Research -Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, 110007, India.; CSIR's Ayurgenomics Unit-TRISUTRA (Translational Research and Innovative Science ThRoughAyurgenomics) CSIR-IGIB, Delhi, 110007, India.; Centre of Excellence for Applied Development of Ayurveda, Prakriti and Genomics, CSIR's Ayurgenomics Unit-TRISUTRA (Translational Research and Innovative Science ThRoughAyurgenomics), CSIR- IGIB, Delhi, 110007, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. PattnaikBR; Center for Translational Research in Lung Disease, CSIR- IGIB, Delhi, 110007, India. Jain V; Center for Translational Research in Lung Disease, CSIR- IGIB, Delhi, 110007, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Parekh Y; CSIR-Center for Cellular and Molecular Biology, Annexe-II, Medical Biotechnology Complex, Uppal Road, Hyderabad, Telangana, 500007, India. Enayathullah MG; CSIR-Center for Cellular and Molecular Biology, Annexe-II, Medical Biotechnology Complex, Uppal Road, Hyderabad, Telangana, 500007, India. Bokara KK; CSIR-Center for Cellular and Molecular Biology, Annexe-II, Medical Biotechnology Complex, Uppal Road, Hyderabad, Telangana, 500007, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Subramanian V; Center for High Computing, CSIR- Central Leather Research Institute (CLRI), Chennai, 600020, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Mukerji M; Genomics and Molecular Medicine, Council of Scientific and Industrial Research -Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, 110007, India.; CSIR's Ayurgenomics Unit-TRISUTRA (Translational Research and Innovative Science ThRoughAyurgenomics) CSIR-IGIB, Delhi, 110007, India.; Centre of Excellence for Applied Development of Ayurveda, Prakriti and Genomics, CSIR's Ayurgenomics Unit-TRISUTRA (Translational Research and Innovative Science ThRoughAyurgenomics), CSIR- IGIB, Delhi, 110007, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Agrawal A; Center for Translational Research in Lung Disease, CSIR- IGIB, Delhi, 110007, India. .; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. . Prasher B; Genomics and Molecular Medicine, Council of Scientific and Industrial Research -Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, 110007, India. .; CSIR's Ayurgenomics Unit-TRISUTRA (Translational Research and Innovative Science ThRoughAyurgenomics) CSIR-IGIB, Delhi, 110007, India. .; Centre of Excellence for Applied Development of Ayurveda, Prakriti and Genomics, CSIR's Ayurgenomics Unit-TRISUTRA (Translational Research and Innovative Science ThRoughAyurgenomics), CSIR- IGIB, Delhi, 110007, India. .; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. .
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Źródło:
Respiratory research [Respir Res] 2021 Apr 06; Vol. 22 (1), pp. 99. Date of Electronic Publication: 2021 Apr 06.
Oxidative stress induced by the anti-cancer agents, plumbagin, and atovaquone, inhibits ion transport through Na -ATPase.
Autorzy:
Alharbi Y; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI, 53792, USA.; Department of Veterinary Medicine, Qassim University, Qassim, Saudi Arabia. Kapur A; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI, 53792, USA. Felder M; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI, 53792, USA. Barroilhet L; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI, 53792, USA. PattnaikBR; Department of Pediatrics, Ophthalmology and Visual Sciences, McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, 53706, USA. pattnaik@wisc.edu. Patankar MS; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI, 53792, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 Nov 11; Vol. 10 (1), pp. 19585. Date of Electronic Publication: 2020 Nov 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Kabra M; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI 53705, USA.; Department of Pediatrics, University of Wisconsin-Madison, Madison, WI 53706, USA. PattnaikBR; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI 53705, USA.; Department of Pediatrics, University of Wisconsin-Madison, Madison, WI 53706, USA.; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI 53705, USA.
Plumbagin-induced oxidative stress leads to inhibition of Na -ATPase (NKA) in canine cancer cells.
Autorzy:
Alharbi Y; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI-53792, USA.; Department of Veterinary Medicine, Qassim University, Qassim, Saudi Arabia. Kapur A; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI-53792, USA. Felder M; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI-53792, USA. Barroilhet L; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI-53792, USA. Stein T; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI-53792, USA.; Austin Veterinary, Austin, TX, 78730, USA. PattnaikBR; Department of Pediatrics and Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI-53706, USA. pattnaik@wisc.edu. Patankar MS; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI-53792, USA. .
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Źródło:
Scientific reports [Sci Rep] 2019 Aug 07; Vol. 9 (1), pp. 11471. Date of Electronic Publication: 2019 Aug 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Pregnancy-adapted uterine artery endothelial cell Ca2+ signaling and its relationship with membrane potential.
Autorzy:
Alvarez RE; Perinatal Research Laboratories, Department of Obstetrics and Gynecology, University of Wisconsin, Madison, Wisconsin. Boeldt DS; Perinatal Research Laboratories, Department of Obstetrics and Gynecology, University of Wisconsin, Madison, Wisconsin. PattnaikBR; Department of Pediatrics, University of Wisconsin, Madison, Wisconsin.; Department of Ophthalmology and Vision Sciences, University of Wisconsin, Madison, Wisconsin. Friedman HL; Perinatal Research Laboratories, Department of Obstetrics and Gynecology, University of Wisconsin, Madison, Wisconsin. Bird IM; Perinatal Research Laboratories, Department of Obstetrics and Gynecology, University of Wisconsin, Madison, Wisconsin .; Department of Pediatrics, University of Wisconsin, Madison, Wisconsin.
Role of the sigma-1 receptor chaperone in rod and cone photoreceptor degenerations in a mouse model of retinitis pigmentosa.
Autorzy:
Yang H; Department of Surgery, Wisconsin Institute for Medical Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA. Fu Y; Department of Surgery, Wisconsin Institute for Medical Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA.; Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 Wanping Nan Road, Shanghai, 200030, People's Republic of China. Liu X; Department of Pediatrics, Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 1300 University Avenue, SMI 112, Madison, WI, 53706, USA. Shahi PK; Department of Pediatrics, Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 1300 University Avenue, SMI 112, Madison, WI, 53706, USA. Mavlyutov TA; Department of Anesthesiology, Wisconsin Institute for Medical Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA. Li J; Department of Surgery, Wisconsin Institute for Medical Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA.; Department of Ophthalmology, the First Hospital of China Medical University, Shenyang, 110001, People's Republic of China.; Department of Ophthalmology, the 3rd People's Hospital of Dalian, Dalian, 116033, People's Republic of China. Yao A; Department of Surgery, Wisconsin Institute for Medical Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA. Guo SZ; Department of Surgery, Wisconsin Institute for Medical Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA. PattnaikBR; Department of Pediatrics, Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 1300 University Avenue, SMI 112, Madison, WI, 53706, USA. pattnaik@wisc.edu.; McPherson Eye Research Institute, University of Wisconsin, Madison, WI, 53705, USA. pattnaik@wisc.edu. Guo LW; Department of Surgery, Wisconsin Institute for Medical Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA. .; McPherson Eye Research Institute, University of Wisconsin, Madison, WI, 53705, USA. .; Department of Surgery and Department of Physiology &Cell Biology, the Ohio State University, Columbus, OH, 43210, USA. .
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Źródło:
Molecular neurodegeneration [Mol Neurodegener] 2017 Sep 19; Vol. 12 (1), pp. 68. Date of Electronic Publication: 2017 Sep 19.
Photoreceptor protection via blockade of BET epigenetic readers in a murine model of inherited retinal degeneration.
Autorzy:
Zhao L; Department of Surgery, 5151 Wisconsin Institute for Medical Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA. Li J; Department of Surgery, 5151 Wisconsin Institute for Medical Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA.; Department of Ophthalmology, The First Hospital of China Medical University, Shenyang, 110001, People's Republic of China.; Department of Ophthalmology, The 3rd People's Hospital of Dalian, Dalian, 116033, People's Republic of China. Fu Y; Department of Surgery, 5151 Wisconsin Institute for Medical Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA.; Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 Wanping Nan Road, Shanghai, 200030, People's Republic of China. Zhang M; Department of Surgery, 5151 Wisconsin Institute for Medical Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA. Wang B; Department of Surgery, 5151 Wisconsin Institute for Medical Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA. Ouellette J; Department of Comparative Biosciences, University of Wisconsin, Madison, WI, 53706, USA. Shahi PK; Department of Pediatrics, University of Wisconsin, Madison, WI, USA.; Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI, USA. PattnaikBR; Department of Pediatrics, University of Wisconsin, Madison, WI, USA.; McPherson Eye Research Institute, University of Wisconsin, Madison, WI, 53705, USA.; Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI, USA. Watters JJ; Department of Comparative Biosciences, University of Wisconsin, Madison, WI, 53706, USA. Wong WT; Unit on Neuron-Glia Interactions in Retinal Disease, National Eye Institute, National Institutes of Health, Bethesda, MD, USA. Guo LW; Department of Surgery, 5151 Wisconsin Institute for Medical Research, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53705, USA. .; McPherson Eye Research Institute, University of Wisconsin, Madison, WI, 53705, USA. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2017 Jan 19; Vol. 14 (1), pp. 14. Date of Electronic Publication: 2017 Jan 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
Snowflake vitreoretinal degeneration (SVD) mutation R162W provides new insights into Kir7.1 ion channel structure and function.
Autorzy:
PattnaikBR; Department of Pediatrics, University of Wisconsin, Madison, Wisconsin, United States of America ; Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin, United States of America ; McPherson Eye Research Institute, University of Wisconsin, Madison, Wisconsin, United States of America. Tokarz S Asuma MP Schroeder T Sharma A Mitchell JC Edwards AO Pillers DA
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Źródło:
PloS one [PLoS One] 2013 Aug 19; Vol. 8 (8), pp. e71744. Date of Electronic Publication: 2013 Aug 19 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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