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    Wyświetlanie 1-18 z 18
    Tytuł:
    Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals.
    Autorzy:
    Grillo AS; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
    SantaMaria AM; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
    Kafina MD; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
    Cioffi AG; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
    Huston NC; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
    Han M; Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
    Seo YA; Department of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.
    Yien YY; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
    Nardone C; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
    Menon AV; Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
    Fan J; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
    Svoboda DC; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
    Anderson JB; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
    Hong JD; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
    Nicolau BG; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
    Subedi K; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
    Gewirth AA; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
    Wessling-Resnick M; Department of Genetic and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. .
    Kim J; Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA. .
    Paw BH; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. .; Division of Hematology-Oncology, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
    Burke MD; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. .; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.; Carle-Illinois College of Medicine, University of Illinois at Urbana-Champaign, Champaign, IL 61820, USA.
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 2017 May 12; Vol. 356 (6338), pp. 608-616.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Iron/*metabolism
    Animals ; Caco-2 Cells ; Gastrointestinal Absorption ; Hemoglobins/metabolism ; Humans ; Iron-Binding Proteins/metabolism ; Monoterpenes/metabolism ; Rats ; Saccharomyces cerevisiae/metabolism ; Tropolone/analogs & derivatives ; Tropolone/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Distinct neuroblastoma-associated alterations of PHOX2B impair sympathetic neuronal differentiation in zebrafish models.
    Autorzy:
    Pei D; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
    Luther W
    Wang W
    Paw BH
    Stewart RA
    George RE
    Pokaż więcej
    Źródło:
    PLoS genetics [PLoS Genet] 2013 Jun; Vol. 9 (6), pp. e1003533. Date of Electronic Publication: 2013 Jun 06.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Neurogenesis*
    Cell Differentiation/*genetics
    Homeodomain Proteins/*genetics
    Neuroblastoma/*genetics
    Transcription Factors/*genetics
    Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; ELAV Proteins/genetics ; ELAV Proteins/metabolism ; ELAV-Like Protein 3 ; Gene Expression Regulation, Developmental ; Genetic Predisposition to Disease ; Heterozygote ; Homeodomain Proteins/metabolism ; Humans ; Neuroblastoma/metabolism ; Neuroblastoma/pathology ; Neurons/cytology ; Neurons/metabolism ; Sympathetic Nervous System/cytology ; Sympathetic Nervous System/pathology ; Transcription Factors/metabolism ; Zebrafish/genetics ; Zebrafish/growth & development ; Zebrafish Proteins/genetics ; Zebrafish Proteins/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II.
    Autorzy:
    Schwarz K; Institute for Transfusion Medicine, University of Ulm, Ulm, Germany. />Iolascon A
    Verissimo F
    Trede NS
    Horsley W
    Chen W
    Paw BH
    Hopfner KP
    Holzmann K
    Russo R
    Esposito MR
    Spano D
    De Falco L
    Heinrich K
    Joggerst B
    Rojewski MT
    Perrotta S
    Denecke J
    Pannicke U
    Delaunay J
    Pepperkok R
    Heimpel H
    Pokaż więcej
    Źródło:
    Nature genetics [Nat Genet] 2009 Aug; Vol. 41 (8), pp. 936-40. Date of Electronic Publication: 2009 Jun 28.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Anemia, Dyserythropoietic, Congenital/*genetics
    COP-Coated Vesicles/*genetics
    Mutation/*genetics
    Vesicular Transport Proteins/*genetics
    Animals ; Cell Line ; Cell Nucleus/genetics ; DNA Mutational Analysis ; Erythroid Cells/metabolism ; Humans ; Jaw/pathology ; Phenotype ; Zebrafish/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins.
    Autorzy:
    Rajagopal A; Department of Animal & Avian Sciences, University of Maryland, College Park, Maryland 20742, USA.
    Rao AU
    Amigo J
    Tian M
    Upadhyay SK
    Hall C
    Uhm S
    Mathew MK
    Fleming MD
    Paw BH
    Krause M
    Hamza I
    Pokaż więcej
    Źródło:
    Nature [Nature] 2008 Jun 19; Vol. 453 (7198), pp. 1127-31. Date of Electronic Publication: 2008 Apr 16.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Homeostasis*
    Caenorhabditis elegans/*metabolism
    Caenorhabditis elegans Proteins/*metabolism
    Heme/*metabolism
    Hemeproteins/*metabolism
    Zebrafish/*metabolism
    Zebrafish Proteins/*metabolism
    Animals ; Biological Transport/drug effects ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans Proteins/genetics ; Cell Line ; Erythropoiesis ; Heme/pharmacology ; Hemeproteins/genetics ; Humans ; Metalloporphyrins/metabolism ; Zebrafish/embryology ; Zebrafish/genetics ; Zebrafish Proteins/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-18 z 18

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