Using the concordance of in vitro and in vivo data to evaluate extrapolation assumptions.
Autorzy:
Honda GS; National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America.; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America. PearceRG; National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America.; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America. Pham LL; National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America.; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America. Setzer RW; National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America. Wetmore BA; National Exposure Research Laboratory, U.S. EPA, Research Triangle Park, North Carolina, United States of America. Sipes NS; Division of the National Toxicology Program, NIEHS, Research Triangle Park, North Carolina, United States of America. Gilbert J; Cyprotex, Watertown, MA, United States of America. Franz B; Cyprotex, Watertown, MA, United States of America. Thomas RS; National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America. Wambaugh JF; National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America.
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Źródło:
PloS one [PLoS One] 2019 May 28; Vol. 14 (5), pp. e0217564. Date of Electronic Publication: 2019 May 28 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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