Autor: "Peng LF" - OpacWWW

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Tytuł:: HCV induces transforming growth factor β1 through activation of endoplasmic reticulum stress and the unfolded protein response.
Autorzy:: Chusri P; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.; Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Kumthip K; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.; Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Hong J; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Zhu C; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.; Department of Infectious Diseases, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Duan X; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.; Institute of Blood Transfusion, Chinese Academy of Medical Sciences and Peking Union Medical College, Chengdu, China.
Jilg N; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Fusco DN; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Brisac C; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Schaefer EA; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Cai D; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.; Department for infectious diseases, The second affiliated hospital of Chongqing medical university, Chongqing 400010, China.
Peng LF; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Maneekarn N; Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Lin W; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Chung RT; Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Mar 01; Vol. 6, pp. 22487. Date of Electronic Publication: 2016 Mar 01.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Endoplasmic Reticulum Stress/*physiology
Endoribonucleases/*metabolism
Hepacivirus/*metabolism
JNK Mitogen-Activated Protein Kinases/*metabolism
NF-kappa B/*metabolism
Protein Serine-Threonine Kinases/*metabolism
Transforming Growth Factor beta1/*metabolism
Unfolded Protein Response/*physiology
Activating Transcription Factor 6/genetics ; Cell Line, Tumor ; Endoribonucleases/antagonists & inhibitors ; Endoribonucleases/genetics ; Humans ; JNK Mitogen-Activated Protein Kinases/antagonists & inhibitors ; JNK Mitogen-Activated Protein Kinases/genetics ; Oxidative Stress/physiology ; Protein Serine-Threonine Kinases/antagonists & inhibitors ; Protein Serine-Threonine Kinases/genetics ; RNA Interference ; RNA, Small Interfering/genetics ; Reactive Oxygen Species/metabolism ; eIF-2 Kinase/genetics

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