Temat: "Penicillin Amidase" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Enhanced catalytic performance of penicillin G acylase by covalent immobilization onto functionally-modified magnetic Ni0.4Cu0.5Zn0.1Fe2O4 nanoparticles.
Autorzy:: Lv Z; The People's Hospital of Danyang, Affiliated Danyang Hospital of Nantong University, Zhenjiang, 212300, P.R. China.
Wang Z; Vanadium and Titanium Resource Comprehensive Utilization Key Laboratory of Sichuan Province, College of Vanadium and Titanium, Panzhihua University, Panzhihua, 617000, P.R. China.
Wu S; Zhenjiang Hospital of Chinese Traditional and Western Medicine, Zhenjiang, 212013, P.R. China.
Yu X; Vanadium and Titanium Resource Comprehensive Utilization Key Laboratory of Sichuan Province, College of Vanadium and Titanium, Panzhihua University, Panzhihua, 617000, P.R. China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Jan 19; Vol. 19 (1), pp. e0297149. Date of Electronic Publication: 2024 Jan 19 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Penicillin Amidase*/chemistry
Penicillin Amidase*/metabolism
Nanoparticles*/chemistry
Glutaral/chemistry ; Silicon Dioxide/chemistry ; Enzymes, Immobilized/chemistry ; Catalysis ; Penicillins ; Magnetic Phenomena ; Hydrogen-Ion Concentration ; Temperature ; Enzyme Stability

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Skocz do pozycji: 2.

Tytuł:: Self-Assembling Enzymatic Nanocomplexes with Polypeptides and Low-Weight Organic Compounds: Preparation, Characterization, and Application of New Antibacterials.
Autorzy:: Lyagin I; Faculty of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.
Stepanov N; Faculty of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.
Presnov D; Skobeltsyn Institute of Nuclear Physics, Lomonosov Moscow State University, 119991 Moscow, Russia.
Trifonov A; Faculty of Physics, Lomonosov Moscow State University, 119991 Moscow, Russia.
Efremenko E; Faculty of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 17; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 17.
Typ publikacji:: Journal Article
MeSH Terms:: Penicillin Amidase*
Emodin*
Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Peptides/chemistry ; Aryldialkylphosphatase/chemistry ; Organic Chemicals

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Skocz do pozycji: 3.

Tytuł:: Immobilization of Penicillin G Acylase on Vinyl Sulfone-Agarose: An Unexpected Effect of the Ionic Strength on the Performance of the Immobilization Process.
Autorzy:: da Rocha TN; Departamento de Biocatálisis, ICP-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain.; Chemical Engineering Department, Campus do Pici, Federal University of Ceará, Bloco 709, Fortaleza CEP 60440-900, CE, Brazil.
Morellon-Sterlling R; Departamento de Biocatálisis, ICP-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain.; Departamento de Biología Molecular, Campus UAM-CSIC, Universidad Autónoma de Madrid, Darwin 2, Cantoblanco, 28049 Madrid, Spain.
Rocha-Martin J; Department of Biochemistry and Molecular Biology, Faculty of Biology, Complutense University of Madrid, José Antonio Novais 12, 28040 Madrid, Spain.
Bolivar JM; FQPIMA Group, Chemical and Materials Engineering Department, Faculty of Chemical Sciences, Complutense University of Madrid, Complutense Ave., 28040 Madrid, Spain.
Gonçalves LRB; Chemical Engineering Department, Campus do Pici, Federal University of Ceará, Bloco 709, Fortaleza CEP 60440-900, CE, Brazil.
Fernandez-Lafuente R; Departamento de Biocatálisis, ICP-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain.; Center of Excellence in Bionanoscience Research, Member of the External Scientific Advisory Board, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Nov 05; Vol. 27 (21). Date of Electronic Publication: 2022 Nov 05.
Typ publikacji:: Journal Article
MeSH Terms:: Penicillin Amidase*/chemistry
Enzyme Stability ; Enzymes, Immobilized/chemistry ; Escherichia coli/metabolism ; Hydrogen-Ion Concentration ; Osmolar Concentration ; Sepharose/chemistry

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Skocz do pozycji: 4.

Tytuł:: Modifying insulin to improve performance.
Autorzy:: Lin NP; Stanford University, School of Medicine, Palo Alto, CA, USA.
Chou DH; Stanford University, School of Medicine, Palo Alto, CA, USA.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2022 Jun 17; Vol. 376 (6599), pp. 1270-1271. Date of Electronic Publication: 2022 Jun 16.
Typ publikacji:: Journal Article; Comment
MeSH Terms:: Insulin*/analogs & derivatives
Insulin*/chemistry
Insulin*/therapeutic use
Penicillin Amidase*/chemistry
Penicillin Amidase*/genetics
Protein Engineering*/methods
Biocatalysis ; Humans

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Skocz do pozycji: 5.

Tytuł:: A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins.
Autorzy:: Fryszkowska A; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
An C; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Alvizo O; Codexis Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA.
Banerjee G; Codexis Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA.
Canada KA; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Cao Y; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
DeMong D; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Devine PN; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Duan D; Codexis Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA.
Elgart DM; Codexis Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA.
Farasat I; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Gauthier DR; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Guidry EN; Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
Jia X; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Kong J; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Kruse N; Codexis Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA.
Lexa KW; Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
Makarov AA; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Mann BF; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Milczek EM; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Mitchell V; Codexis Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA.
Nazor J; Codexis Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA.
Neri C; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Orr RK; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Orth P; Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA.
Phillips EM; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Riggins JN; Codexis Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA.
Schafer WA; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Silverman SM; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Strulson CA; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Subramanian N; Codexis Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA.
Voladri R; Codexis Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA.
Yang H; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.
Yang J; Codexis Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA.
Yi X; Codexis Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA.
Zhang X; Codexis Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA.
Zhong W; Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2022 Jun 17; Vol. 376 (6599), pp. 1321-1327. Date of Electronic Publication: 2022 Jun 16.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin*/analogs & derivatives
Insulin*/biosynthesis
Penicillin Amidase*/chemistry
Penicillin Amidase*/genetics
Peptides*/chemistry
Peptides*/genetics
Protein Engineering*/methods
Amino Acid Sequence ; Humans ; Lysine/chemistry

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Skocz do pozycji: 6.

Tytuł:: Comparative study of poly tannic acid functionalized magnetic particles before and after modification for immobilized penicillin G acylase.
Autorzy:: Tu H; School of Materials Science and Engineering, Lanzhou University of Technology, Lanzhou, China.; State Key Laboratory of Advanced progressing and Recycling of Nonferrous Metal Materials, Lanzhou University of Technology, Lanzhou, China.
Gao K; School of Materials Science and Engineering, Lanzhou University of Technology, Lanzhou, China.; State Key Laboratory of Advanced progressing and Recycling of Nonferrous Metal Materials, Lanzhou University of Technology, Lanzhou, China.
Zhang B; School of Materials Science and Engineering, Lanzhou University of Technology, Lanzhou, China.; State Key Laboratory of Advanced progressing and Recycling of Nonferrous Metal Materials, Lanzhou University of Technology, Lanzhou, China.
Chen Z; School of Materials Science and Engineering, Lanzhou University of Technology, Lanzhou, China.; State Key Laboratory of Advanced progressing and Recycling of Nonferrous Metal Materials, Lanzhou University of Technology, Lanzhou, China.
Wang P; School of Materials Science and Engineering, Lanzhou University of Technology, Lanzhou, China.; State Key Laboratory of Advanced progressing and Recycling of Nonferrous Metal Materials, Lanzhou University of Technology, Lanzhou, China.
Li Z; School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, China.; Pokaż więcej
Źródło:: Journal of biomaterials science. Polymer edition [J Biomater Sci Polym Ed] 2022 May; Vol. 33 (7), pp. 823-846. Date of Electronic Publication: 2021 Dec 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Magnetite Nanoparticles*/chemistry
Penicillin Amidase*/chemistry
Enzymes, Immobilized/chemistry ; Glutaral/chemistry ; Magnetic Phenomena ; Tannins/chemistry

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Skocz do pozycji: 7.

Tytuł:: Production and secretion dynamics of prokaryotic Penicillin G acylase in Pichia pastoris.
Autorzy:: Borčinová M; Institute of Chemistry and Biotechnology, Zurich University of Applied Sciences, Campus Grüental, CH-8820, Wädenswil, Switzerland. .; Department of Genetics and Microbiology, Faculty of Science, Charles University in Prague, Viničná 5, 12840, Prague, Czech Republic. .
Raschmanová H; Institute of Chemistry and Biotechnology, Zurich University of Applied Sciences, Campus Grüental, CH-8820, Wädenswil, Switzerland.; Department of Biotechnology, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Technická 5, 16628, Prague, Czech Republic.
Zamora I; Institute of Chemistry and Biotechnology, Zurich University of Applied Sciences, Campus Grüental, CH-8820, Wädenswil, Switzerland.; Infors AG, Rittergasse 27, CH-4103, Bottmingen, Switzerland.
Looser V; Institute of Chemistry and Biotechnology, Zurich University of Applied Sciences, Campus Grüental, CH-8820, Wädenswil, Switzerland.; Department of Biotechnology, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Technická 5, 16628, Prague, Czech Republic.
Marešová H; Institute of Microbiology, Czech Academy of Sciences, Videňská 1083, 14220, Prague, Czech Republic.
Hirsch S; Institute of Applied Simulation, Zurich University of Applied Sciences, Schloss 1, CH-8820, Wädenswil, Switzerland.
Kyslík P; Institute of Microbiology, Czech Academy of Sciences, Videňská 1083, 14220, Prague, Czech Republic.
Kovar K; Institute of Chemistry and Biotechnology, Zurich University of Applied Sciences, Campus Grüental, CH-8820, Wädenswil, Switzerland.; Daspool, Gerberacherweg 24, CH-8820, Wädenswil, Switzerland.; Pokaż więcej
Źródło:: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2020 Jul; Vol. 104 (13), pp. 5787-5800. Date of Electronic Publication: 2020 May 18.
Typ publikacji:: Journal Article
MeSH Terms:: Bacterial Proteins/*metabolism
Penicillin Amidase/*metabolism
Saccharomycetales/*metabolism
Bacterial Proteins/genetics ; Batch Cell Culture Techniques ; Biomass ; Bioreactors ; Extracellular Space/metabolism ; Intracellular Space/metabolism ; Kinetics ; Models, Theoretical ; Penicillin Amidase/genetics ; Promoter Regions, Genetic ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Saccharomycetales/genetics ; Saccharomycetales/growth & development
SCR Organism:: Komagataella pastoris

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Skocz do pozycji: 8.

Tytuł:: Modelling of substrate access and substrate binding to cephalosporin acylases.
Autorzy:: Ferrario V; Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, Allmandring 31, 70569, Stuttgart, Germany.
Fischer M; Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, Allmandring 31, 70569, Stuttgart, Germany.
Zhu Y; Department of Chemical Engineering, Tsinghua University, Beijing, 100084, China.
Pleiss J; Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, Allmandring 31, 70569, Stuttgart, Germany. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Aug 27; Vol. 9 (1), pp. 12402. Date of Electronic Publication: 2019 Aug 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bacterial Proteins/*metabolism
Penicillin Amidase/*metabolism
Pseudomonas/*enzymology
Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Binding Sites ; Biocatalysis ; Catalytic Domain ; Cephalosporins/chemistry ; Cephalosporins/metabolism ; Kinetics ; Molecular Dynamics Simulation ; Penicillin Amidase/chemistry ; Penicillin Amidase/genetics ; Protein Engineering ; Substrate Specificity ; Thermodynamics

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Skocz do pozycji: 9.

Tytuł:: Crystal structures and protein engineering of three different penicillin G acylases from Gram-positive bacteria with different thermostability.
Autorzy:: Mayer J; Institute of Microbiology and Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Rebenring 56, 38106, Braunschweig, Germany.
Pippel J; HZI - Helmholtz Centre for Infection Research, Structure and Function of Proteins, Inhoffenstraße 7, 38124, Braunschweig, Germany.
Günther G; Institute of Microbiology and Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Rebenring 56, 38106, Braunschweig, Germany.
Müller C; Institute of Microbiology and Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Rebenring 56, 38106, Braunschweig, Germany.
Lauermann A; Institute of Microbiology and Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Rebenring 56, 38106, Braunschweig, Germany.
Knuuti T; Institute of Microbiology and Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Rebenring 56, 38106, Braunschweig, Germany.
Blankenfeldt W; HZI - Helmholtz Centre for Infection Research, Structure and Function of Proteins, Inhoffenstraße 7, 38124, Braunschweig, Germany.; Institute of Biotechnology, Biochemistry and Bioinformatics, Technische Universität Braunschweig, Spielmannstr. 7, 38106, Braunschweig, Germany.
Jahn D; Institute of Microbiology and Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Rebenring 56, 38106, Braunschweig, Germany.
Biedendieck R; Institute of Microbiology and Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Rebenring 56, 38106, Braunschweig, Germany. .; Pokaż więcej
Źródło:: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2019 Sep; Vol. 103 (18), pp. 7537-7552. Date of Electronic Publication: 2019 Jun 21.
Typ publikacji:: Journal Article
MeSH Terms:: Bacillus megaterium/*enzymology
Penicillin Amidase/*chemistry
Protein Engineering/*methods
Bacillus megaterium/genetics ; Biochemical Phenomena ; Biotechnology ; Crystallization ; Enzyme Stability ; Hydrolysis ; Penicillin Amidase/genetics

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Skocz do pozycji: 10.

Tytuł:: Efficient synthesis of β-lactam antibiotics with very low product hydrolysis by a mutant Providencia rettgeri penicillin G acylase.
Autorzy:: Pan X; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, Jiangsu, 211816, China.
Wang L; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, Jiangsu, 211816, China.
Ye J; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, Jiangsu, 211816, China.
Qin S; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, Jiangsu, 211816, China.
He B; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, Jiangsu, 211816, China. .; Pokaż więcej
Źródło:: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2018 Feb; Vol. 102 (4), pp. 1749-1758. Date of Electronic Publication: 2018 Jan 06.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Bacterial Agents/*metabolism
Mutant Proteins/*metabolism
Penicillin Amidase/*metabolism
Providencia/*enzymology
Providencia/*metabolism
beta-Lactams/*metabolism
Amoxicillin/metabolism ; Cefadroxil/metabolism ; Glycine/analogs & derivatives ; Glycine/metabolism ; Hydrolysis ; Kinetics ; Molecular Docking Simulation ; Mutagenesis, Site-Directed ; Mutant Proteins/genetics ; Penicillin Amidase/genetics ; Penicillin Amidase/isolation & purification ; Time Factors

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Skocz do pozycji: 11.

Tytuł:: Penicillin V acylases from gram-negative bacteria degrade N-acylhomoserine lactones and attenuate virulence in Pseudomonas aeruginosa.
Autorzy:: Sunder AV; Division of Biochemical Sciences, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, 411008, India.
Utari PD; Department of Pharmaceutical Biology, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
Ramasamy S; Division of Biochemical Sciences, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, 411008, India.
van Merkerk R; Department of Pharmaceutical Biology, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
Quax W; Department of Pharmaceutical Biology, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
Pundle A; Division of Biochemical Sciences, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, 411008, India. .; Pokaż więcej
Źródło:: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2017 Mar; Vol. 101 (6), pp. 2383-2395. Date of Electronic Publication: 2016 Dec 08.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Bacterial*
Acyl-Butyrolactones/*chemistry
Bacterial Proteins/*chemistry
Penicillin Amidase/*chemistry
Pseudomonas aeruginosa/*genetics
Pseudomonas aeruginosa/*pathogenicity
Acyl-Butyrolactones/metabolism ; Agrobacterium tumefaciens/enzymology ; Agrobacterium tumefaciens/genetics ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Biofilms/growth & development ; Catalytic Domain ; Cloning, Molecular ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Hydrolysis ; Models, Molecular ; Pancreatic Elastase/biosynthesis ; Pectobacterium/enzymology ; Pectobacterium/genetics ; Penicillin Amidase/genetics ; Penicillin Amidase/metabolism ; Protein Conformation ; Pseudomonas aeruginosa/metabolism ; Pyocyanine/biosynthesis ; Quorum Sensing ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Substrate Specificity ; Virulence

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Skocz do pozycji: 12.

Tytuł:: Computational design of variants for cephalosporin C acylase from Pseudomonas strain N176 with improved stability and activity.
Autorzy:: Tian Y; Department of Chemical Engineering, Tsinghua University, Beijing, 100084, People's Republic of China.
Huang X; Department of Chemical Engineering, Tsinghua University, Beijing, 100084, People's Republic of China.
Li Q; Department of Chemical Engineering, Tsinghua University, Beijing, 100084, People's Republic of China.
Zhu Y; Department of Chemical Engineering, Tsinghua University, Beijing, 100084, People's Republic of China. .; MOE Key Lab of Industrial Biocatalysis, Tsinghua University, Beijing, 100084, People's Republic of China. .; Pokaż więcej
Źródło:: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2017 Jan; Vol. 101 (2), pp. 621-632. Date of Electronic Publication: 2016 Aug 24.
Typ publikacji:: Journal Article
MeSH Terms:: Cephalosporins/*metabolism
Penicillin Amidase/*chemistry
Penicillin Amidase/*metabolism
Protein Engineering/*methods
Pseudomonas/*enzymology
Enzyme Stability ; Kinetics ; Mutant Proteins/chemistry ; Mutant Proteins/genetics ; Mutant Proteins/metabolism ; Penicillin Amidase/genetics ; Point Mutation ; Temperature

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Skocz do pozycji: 13.

Tytuł:: Effect of Concentrated Salts Solutions on the Stability of Immobilized Enzymes: Influence of Inactivation Conditions and Immobilization Protocol.
Autorzy:: Braham SA; Departamento de Biocatálisis, ICP-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain.; Laboratoire de Biotechnologies Végétales et Ethnobotanique, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, Bejaia 06000, Algeria.
Siar EH; Departamento de Biocatálisis, ICP-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain.; Transformation and Food Product Elaboration Laboratory, Nutrition and Food Technology Institute (INATAA), University of Brothers Mentouri Constantine 1, Constantine 25017, Algeria.
Arana-Peña S; Departamento de Biocatálisis, ICP-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain.
Carballares D; Departamento de Biocatálisis, ICP-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain.
Morellon-Sterling R; Departamento de Biocatálisis, ICP-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain.
Bavandi H; Departamento de Biocatálisis, ICP-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain.; Department of Pure Chemistry, Faculty of Chemistry, Shahid Beheshti University, G.C., Tehran 1983969411, Iran.
de Andrades D; Departamento de Biocatálisis, ICP-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain.; Biotechnology, Bioprocess, and Biocatalysis Group, Food Science and Technology Institute, Federal University of Rio Grande do Sul, Porto Alegre 90040-060, RS, Brazil.
Kornecki JF; Departamento de Biocatálisis, ICP-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain.
Fernandez-Lafuente R; Departamento de Biocatálisis, ICP-CSIC, Campus UAM-CSIC, 28049 Madrid, Spain.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Feb 12; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 12.
Typ publikacji:: Journal Article
MeSH Terms:: Enzyme Stability/*drug effects
Enzymes, Immobilized/*chemistry
Salts/*chemistry
Catalase/chemistry ; Enzymes, Immobilized/antagonists & inhibitors ; Glycoside Hydrolases/chemistry ; Hydrogen-Ion Concentration ; Kinetics ; Laccase/chemistry ; Lipase/chemistry ; Organic Chemicals/chemistry ; Penicillin Amidase/chemistry ; Peptide Hydrolases/chemistry ; Salts/pharmacology ; Solutions/chemistry ; Solutions/pharmacology ; Temperature

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Skocz do pozycji: 14.

Tytuł:: Penicillin acylases revisited: importance beyond their industrial utility.
Autorzy:: Avinash VS; a Division of Biochemical Sciences, CSIR-National , National Chemical Laboratory , Pune , India.
Pundle AV; a Division of Biochemical Sciences, CSIR-National , National Chemical Laboratory , Pune , India.
Ramasamy S; a Division of Biochemical Sciences, CSIR-National , National Chemical Laboratory , Pune , India.
Suresh CG; a Division of Biochemical Sciences, CSIR-National , National Chemical Laboratory , Pune , India.; Pokaż więcej
Źródło:: Critical reviews in biotechnology [Crit Rev Biotechnol] 2016; Vol. 36 (2), pp. 303-16. Date of Electronic Publication: 2014 Nov 28.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Bacterial Proteins*
Penicillin Amidase*
Models, Molecular

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Skocz do pozycji: 15.

Tytuł:: Engineering of a CPC acylase using a facile pH indicator assay.
Autorzy:: Xiao Y; Department of Chemical Engineering, National Engineering Laboratory for Industrial Enzymes, Tsinghua University, One Tsinghua Garden Road, Beijing, 100084, China.
Huo X
Qian Y
Zhang Y
Chen G
Ouyang P
Lin Z; Pokaż więcej
Źródło:: Journal of industrial microbiology & biotechnology [J Ind Microbiol Biotechnol] 2014 Nov; Vol. 41 (11), pp. 1617-25. Date of Electronic Publication: 2014 Sep 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Protein Engineering*
Cephalosporins/*biosynthesis
Cephalosporins/*metabolism
Penicillin Amidase/*genetics
Penicillin Amidase/*metabolism
Catalytic Domain ; Cephalosporins/chemistry ; Enzyme Assays ; Hydrogen-Ion Concentration ; Models, Molecular ; Mutagenesis, Site-Directed ; Penicillin Amidase/chemistry ; Pseudomonas/enzymology

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Skocz do pozycji: 16.

Tytuł:: Computational design of a pH stable enzyme: understanding molecular mechanism of penicillin acylase's adaptation to alkaline conditions.
Autorzy:: Suplatov D; Lomonosov Moscow State University, Belozersky Institute of Physicochemical Biology and Faculty of Bioengineering and Bioinformatics, Moscow, Russia.
Panin N; Lomonosov Moscow State University, Belozersky Institute of Physicochemical Biology and Faculty of Bioengineering and Bioinformatics, Moscow, Russia.
Kirilin E; Lomonosov Moscow State University, Belozersky Institute of Physicochemical Biology and Faculty of Bioengineering and Bioinformatics, Moscow, Russia.
Shcherbakova T; Lomonosov Moscow State University, Belozersky Institute of Physicochemical Biology and Faculty of Bioengineering and Bioinformatics, Moscow, Russia.
Kudryavtsev P; Lomonosov Moscow State University, Belozersky Institute of Physicochemical Biology and Faculty of Bioengineering and Bioinformatics, Moscow, Russia.
Svedas V; Lomonosov Moscow State University, Belozersky Institute of Physicochemical Biology and Faculty of Bioengineering and Bioinformatics, Moscow, Russia.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Jun 24; Vol. 9 (6), pp. e100643. Date of Electronic Publication: 2014 Jun 24 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Penicillin Amidase/*chemistry
Adaptation, Physiological ; Amino Acid Substitution ; Enzyme Activation ; Enzyme Stability ; Hydrogen Bonding ; Hydrogen-Ion Concentration ; Models, Molecular ; Mutation ; Penicillin Amidase/genetics ; Penicillin Amidase/metabolism ; Protein Binding ; Protein Conformation ; Protein Interaction Domains and Motifs ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Temperature