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    Wyświetlanie 1-5 z 5
    Tytuł:
    IPSE, a urogenital parasite-derived immunomodulatory molecule, suppresses bladder pathogenesis and anti-microbial peptide gene expression in bacterial urinary tract infection.
    Autorzy:
    Mbanefo EC; Division of Urology, Department of Surgery, Children's National Hospital, West Wing, 4th Floor, 111 Michigan Avenue NW, Washington, DC, 20010, USA.; National Institutes of Health, Bethesda, MD, USA.
    Le L; Biomedical Research Institute, Rockville, MD, USA.; A-TEK, Baltimore, MD, USA.
    Pennington LF; Department of Structural Biology, Stanford University, Stanford, CA, USA.
    Hsieh YJ; Biomedical Research Institute, Rockville, MD, USA.; Fountain Biopharma, Taipei, Taiwan.
    Odegaard JI; Guardant Health, Redwood City, CA, USA.
    Lapira K; University of California San Diego, La Jolla, USA.
    Jardetzky TS; Department of Structural Biology, Stanford University, Stanford, CA, USA.
    Falcone FH; Institute of Parasitology, Justus-Liebig-Universität Gießen, Gießen, Germany.
    Hsieh MH; Division of Urology, Department of Surgery, Children's National Hospital, West Wing, 4th Floor, 111 Michigan Avenue NW, Washington, DC, 20010, USA. .
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    Źródło:
    Parasites & vectors [Parasit Vectors] 2020 Dec 09; Vol. 13 (1), pp. 615. Date of Electronic Publication: 2020 Dec 09.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Gene Expression*
    Immunomodulation*
    Urinary Bladder/*parasitology
    Urinary Tract Infections/*immunology
    Urinary Tract Infections/*parasitology
    Animals ; Basophils ; Coinfection ; Egg Proteins ; Escherichia coli ; Female ; Helminth Proteins/genetics ; Interleukin-4 ; Male ; Mice ; Mice, Inbred BALB C ; Schistosoma mansoni ; Schistosomiasis haematobia ; Urinary Bladder/microbiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    IPSE, an abundant egg-secreted protein of the carcinogenic helminth Schistosoma haematobium , promotes proliferation of bladder cancer cells and angiogenesis.
    Autorzy:
    Mbanefo EC; Division of Urology, Department of Surgery, Children's National Hospital, West Wing, 4th Floor, 111 Michigan Avenue NW, Washington, DC 20010 USA.
    Agbo CT; Carney Hospital, Boston, MA USA.
    Zhao Y; Mountainview Hospital, Las Vegas, NV USA.
    Lamanna OK; Division of Urology, Department of Surgery, Children's National Hospital, West Wing, 4th Floor, 111 Michigan Avenue NW, Washington, DC 20010 USA.
    Thai KH; Baylor Scott and White Health, Temple, TX USA.
    Karinshak SE; Department of Microbiology, Immunology, and Tropical Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, DC USA.
    Khan MA; King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia.
    Fu CL; Abbvie, Sunnyvale, CA USA.
    Odegaard JI; Guardant Health, Redwood City, CA USA.
    Saltikova IV; Guardant Health, Redwood City, CA USA.; Siberian State Medical University, Tomsk, Russian Federation.
    Smout MJ; James Cook University, Townsville, Australia.
    Pennington LF; Department of Structural Biology, Stanford University, Stanford, CA USA.
    Nicolls MR; Division of Pulmonology, Allergy, and Critical Care Medicine, Stanford University, Stanford, CA USA.
    Jardetzky TS; Department of Structural Biology, Stanford University, Stanford, CA USA.
    Loukas A; James Cook University, Townsville, Australia.
    Brindley PJ; Department of Microbiology, Immunology, and Tropical Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, DC USA.
    Falcone FH; Institute of Parasitology, Justus-Liebig-Universität Gießen, Gießen, Germany.
    Hsieh MH; Division of Urology, Department of Surgery, Children's National Hospital, West Wing, 4th Floor, 111 Michigan Avenue NW, Washington, DC 20010 USA.
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    Źródło:
    Infectious agents and cancer [Infect Agent Cancer] 2020 Oct 22; Vol. 15, pp. 63. Date of Electronic Publication: 2020 Oct 22 (Print Publication: 2020).
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    IPSE, a parasite-derived, host immunomodulatory infiltrin protein, alleviates resiniferatoxin-induced bladder pain.
    Autorzy:
    Ishida K; Division of Urology, Department of Surgery, Children's National Hospital, Washington, DC, USA.
    Mbanefo EC; Division of Urology, Department of Surgery, Children's National Hospital, Washington, DC, USA.
    Le L; Biomedical Research Institute, Rockville, MD, USA.
    Lamanna O; Division of Urology, Department of Surgery, Children's National Hospital, Washington, DC, USA.
    Pennington LF; Department of Structural Biology, Stanford University, Stanford, CA, USA.
    Finkel JC; Department of Anesthesiology, Pain and Perioperative Medicine, Children's National Hospital, Washington, DC, USA.
    Jardetzky TS; Department of Structural Biology, Stanford University, Stanford, CA, USA.
    Falcone FH; Institute of Parasitology, Justus-Liebig-Universität Gießen, Gießen, Germany.
    Hsieh MH; Division of Urology, Department of Surgery, Children's National Hospital, Washington, DC, USA.
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    Źródło:
    Molecular pain [Mol Pain] 2020 Jan-Dec; Vol. 16, pp. 1744806920970099.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Diterpenes/*adverse effects
    Egg Proteins/*therapeutic use
    Helminth Proteins/*therapeutic use
    Host-Parasite Interactions/*immunology
    Immunologic Factors/*therapeutic use
    Pain/*drug therapy
    Parasites/*chemistry
    Urinary Bladder/*pathology
    Animals ; Cell Nucleus/drug effects ; Cell Nucleus/metabolism ; Egg Proteins/pharmacology ; Endocytosis/drug effects ; Female ; Gene Expression Profiling ; Gene Expression Regulation/drug effects ; Helminth Proteins/pharmacology ; Humans ; Immunologic Factors/pharmacology ; Interleukin-4/metabolism ; Mice, Inbred C57BL ; NF-kappa B/metabolism ; Neurons/drug effects ; Neurons/metabolism ; Nuclear Localization Signals/metabolism ; Pain/genetics ; Principal Component Analysis ; Protein Transport/drug effects ; Signal Transduction/drug effects ; Tumor Necrosis Factor-alpha/metabolism ; Urinary Bladder/drug effects ; Urothelium/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    IPSE, a urogenital parasite-derived immunomodulatory protein, ameliorates ifosfamide-induced hemorrhagic cystitis through downregulation of pro-inflammatory pathways.
    Autorzy:
    Mbanefo EC; Bladder Immunology Group, Biomedical Research Institute, Rockville, MD, USA.; Division of Urology, Children's National Medical Center, Washington, DC, USA.
    Le L; Bladder Immunology Group, Biomedical Research Institute, Rockville, MD, USA.
    Zee R; Bladder Immunology Group, Biomedical Research Institute, Rockville, MD, USA.; Division of Urology, Children's National Medical Center, Washington, DC, USA.
    Banskota N; Bladder Immunology Group, Biomedical Research Institute, Rockville, MD, USA.
    Ishida K; Bladder Immunology Group, Biomedical Research Institute, Rockville, MD, USA.
    Pennington LF; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
    Odegaard JI; Guardant Health, Redwood City, CA, USA.
    Jardetzky TS; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
    Alouffi A; Life Science & Environment Sector, King Abdulaziz City for Science & Technology (KACST), Riyadh, Saudi Arabia.
    Falcone FH; Division of Molecular Therapeutics and Formulation, School of Pharmacy, University of Nottingham, Nottingham, UK.
    Hsieh MH; Bladder Immunology Group, Biomedical Research Institute, Rockville, MD, USA. .; Division of Urology, Children's National Medical Center, Washington, DC, USA. .; Department of Urology, The George Washington University, Washington, DC, USA. .
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    Źródło:
    Scientific reports [Sci Rep] 2019 Feb 07; Vol. 9 (1), pp. 1586. Date of Electronic Publication: 2019 Feb 07.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antineoplastic Agents, Alkylating/*adverse effects
    Cystitis/*etiology
    Cystitis/*metabolism
    Egg Proteins/*immunology
    Helminth Proteins/*immunology
    Hemorrhage/*etiology
    Hemorrhage/*metabolism
    Ifosfamide/*adverse effects
    Signal Transduction/*drug effects
    Cystitis/diagnosis ; Cytokines/metabolism ; Gene Expression Profiling ; Hemorrhage/diagnosis ; Inflammation Mediators/metabolism ; Oxidative Stress ; Transcriptome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A new mouse model for female genital schistosomiasis.
    Autorzy:
    Richardson ML; Departments of Ob/Gyn and Urology, Female Pelvic Medicine and Reconstructive Surgery, Stanford University School of Medicine, Palo Alto, California, United States of America.
    Fu CL; Department of Urology, Stanford University School of Medicine, Palo Alto, California, United States of America.
    Pennington LF; Department of Urology, Stanford University School of Medicine, Palo Alto, California, United States of America.
    Honeycutt JD; Department of Urology, Stanford University School of Medicine, Palo Alto, California, United States of America.
    Odegaard JI
    Hsieh YJ; Department of Urology, Stanford University School of Medicine, Palo Alto, California, United States of America.
    Hammam O; Department of Urology, Stanford University School of Medicine, Palo Alto, California, United States of America.
    Conti SL; Department of Urology, Stanford University School of Medicine, Palo Alto, California, United States of America.
    Hsieh MH; Department of Urology, Stanford University School of Medicine, Palo Alto, California, United States of America.
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    Źródło:
    PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2014 May 01; Vol. 8 (5), pp. e2825. Date of Electronic Publication: 2014 May 01 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Disease Models, Animal*
    Schistosomiasis haematobia/*immunology
    Schistosomiasis haematobia/*parasitology
    Vagina/*parasitology
    Animals ; Chemokine CCL5/blood ; Cytokines/blood ; Female ; Granuloma/immunology ; Granuloma/parasitology ; Mice ; Mice, Inbred BALB C ; Oocysts/immunology ; Schistosoma haematobium/immunology ; Vagina/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-5 z 5

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