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    Wyświetlanie 1-13 z 13
    Tytuł:
    Additional Genetic Alterations and Clonal Evolution of MPNs with Double Mutations on the MPL Gene: Two Case Reports.
    Autorzy:
    Pennisi MS; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.
    Di Gregorio S; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.
    Tirrò E; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.
    Romano C; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.
    Duminuco A; Postgraduate School of Hematology, University of Catania, 95123 Catania, Italy.
    Garibaldi B; Postgraduate School of Hematology, University of Catania, 95123 Catania, Italy.
    Giuffrida G; Hematology Unit and Bone Marrow Transplant, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.
    Manzella L; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.
    Vigneri P; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.
    Palumbo GA; Department of Medical, Surgical Sciences and Advanced Technologies, 'G.F. Ingrassia', University of Catania, 95123 Catania, Italy.
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    Źródło:
    Hematology reports [Hematol Rep] 2023 May 23; Vol. 15 (2), pp. 317-324. Date of Electronic Publication: 2023 May 23.
    Typ publikacji:
    Case Reports
    Raport
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Impact of Different Cell Counting Methods in Molecular Monitoring of Chronic Myeloid Leukemia Patients.
    Autorzy:
    Stella S; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Vitale SR; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Stagno F; Division of Hematology and Bone Marrow Transplant, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Massimino M; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Puma A; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Tomarchio C; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Pennisi MS; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Tirrò E; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.; Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, 90127 Palermo, Italy.
    Romano C; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Di Raimondo F; Division of Hematology and Bone Marrow Transplant, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.; Department of Surgery, Medical and Surgical Specialities, Section of Hematology, University of Catania, 95123 Catania, Italy.
    Cacciola E; Department of Medical, Surgical Sciences and Advanced Technologies 'G.F. Ingrassia', University of Catania, 95123 Catania, Italy.; Hemostasis/Hematology Unit, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Cacciola R; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Hemostasis/Hematology Unit, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Manzella L; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
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    Źródło:
    Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2022 Apr 22; Vol. 12 (5). Date of Electronic Publication: 2022 Apr 22.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Combined Inhibition of Bcl2 and Bcr-Abl1 Exercises Anti-Leukemia Activity but Does Not Eradicate the Primitive Leukemic Cells.
    Autorzy:
    Massimino M; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-S. Marco', 95123 Catania, Italy.
    Vigneri P; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-S. Marco', 95123 Catania, Italy.
    Stella S; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-S. Marco', 95123 Catania, Italy.
    Tirrò E; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-S. Marco', 95123 Catania, Italy.
    Pennisi MS; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-S. Marco', 95123 Catania, Italy.
    Parrinello LN; Division of Hematology, A.O.U. Policlinico 'G. Rodolico-S. Marco', 95123 Catania, Italy.
    Vetro C; Division of Hematology, A.O.U. Policlinico 'G. Rodolico-S. Marco', 95123 Catania, Italy.
    Manzella L; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-S. Marco', 95123 Catania, Italy.
    Stagno F; Division of Hematology, A.O.U. Policlinico 'G. Rodolico-S. Marco', 95123 Catania, Italy.
    Di Raimondo F; Division of Hematology, A.O.U. Policlinico 'G. Rodolico-S. Marco', 95123 Catania, Italy.
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    Źródło:
    Journal of clinical medicine [J Clin Med] 2021 Nov 29; Vol. 10 (23). Date of Electronic Publication: 2021 Nov 29.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A Novel System for Semiautomatic Sample Processing in Chronic Myeloid Leukaemia: Increasing Throughput without Impacting on Molecular Monitoring at Time of SARS-CoV-2 Pandemic.
    Autorzy:
    Stella S; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Vitale SR; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Massimino M; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Puma A; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Tomarchio C; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Pennisi MS; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Tirrò E; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.; Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, 90121 Palermo, Italy.
    Romano C; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Martorana F; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Stagno F; Division of Hematology and Bone Marrow Transplant, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Di Raimondo F; Division of Hematology and Bone Marrow Transplant, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.; Hematology Department of Surgery, Medical and Surgical Specialities, University of Catania, 95123 Catania, Italy.
    Manzella L; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
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    Źródło:
    Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2021 Aug 20; Vol. 11 (8). Date of Electronic Publication: 2021 Aug 20.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Opportunities and Challenges of Liquid Biopsy in Thyroid Cancer.
    Autorzy:
    Romano C; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
    Martorana F; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
    Pennisi MS; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
    Stella S; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
    Massimino M; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
    Tirrò E; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.; Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, 90127 Palermo, Italy.
    Vitale SR; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
    Di Gregorio S; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
    Puma A; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
    Tomarchio C; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
    Manzella L; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G. Rodolico-San Marco', 95123 Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2021 Jul 19; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 19.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Liquid Biopsy/*methods
    Thyroid Neoplasms/*blood
    Thyroid Neoplasms/*pathology
    Biomarkers, Tumor/blood ; Cell-Free Nucleic Acids/blood ; Extracellular Vesicles/pathology ; Humans ; Liquid Biopsy/trends ; Neoplastic Cells, Circulating/pathology ; Prognosis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Molecular Pathogenesis and Treatment Perspectives for Hypereosinophilia and Hypereosinophilic Syndromes.
    Autorzy:
    Stella S; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Massimino M; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Manzella L; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Pennisi MS; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Tirrò E; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Romano C; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Vitale SR; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Puma A; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Tomarchio C; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Gregorio SD; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
    Palumbo GA; Department of Scienze Mediche Chirurgiche e Tecnologie Avanzate 'G.F. Ingrassia', University of Catania, 95123 Catania, Italy.
    Vigneri P; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico 'G.Rodolico-San Marco', 95123 Catania, Italy.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2021 Jan 06; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 06.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Hypereosinophilic Syndrome/*pathology
    Receptors, Antigen, T-Cell/*genetics
    Antibodies, Monoclonal/therapeutic use ; Cytokines/metabolism ; Eosinophils/cytology ; Eosinophils/metabolism ; Gene Rearrangement ; Humans ; Hypereosinophilic Syndrome/drug therapy ; Hypereosinophilic Syndrome/genetics ; Protein Kinase Inhibitors/therapeutic use ; Receptor, Platelet-Derived Growth Factor alpha/genetics ; Receptor, Platelet-Derived Growth Factor beta/genetics ; Receptor, Platelet-Derived Growth Factor beta/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Rapid decline of Philadelphia-positive metaphases after nilotinib treatment in a CML patient expressing a rare e14a3 BCR-ABL1 fusion transcript: A case report.
    Autorzy:
    Massimino M; Department of Clinical and Experimental Medicine, University of Catania, Catania I-95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, Catania I-95123, Italy.
    Stella S; Department of Clinical and Experimental Medicine, University of Catania, Catania I-95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, Catania I-95123, Italy.
    Tirrò E; Department of Clinical and Experimental Medicine, University of Catania, Catania I-95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, Catania I-95123, Italy.
    Consoli ML; Division of Hematology and Bone Marrow Transplant, A.O.U. Policlinico-Vittorio Emanuele, Catania I-95123, Italy.
    Pennisi MS; Department of Clinical and Experimental Medicine, University of Catania, Catania I-95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, Catania I-95123, Italy.
    Puma A; Department of Clinical and Experimental Medicine, University of Catania, Catania I-95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, Catania I-95123, Italy.
    Vitale SR; Department of Clinical and Experimental Medicine, University of Catania, Catania I-95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, Catania I-95123, Italy.
    Romano C; Department of Clinical and Experimental Medicine, University of Catania, Catania I-95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, Catania I-95123, Italy.
    Zammit V; Division of Hematology and Bone Marrow Transplant, A.O.U. Policlinico-Vittorio Emanuele, Catania I-95123, Italy.
    Stagno F; Division of Hematology and Bone Marrow Transplant, A.O.U. Policlinico-Vittorio Emanuele, Catania I-95123, Italy.
    Di Raimondo F; Division of Hematology and Bone Marrow Transplant, A.O.U. Policlinico-Vittorio Emanuele, Catania I-95123, Italy.; Department of Surgery, Medical and Surgical Specialties, University of Catania, Catania I-95123, Italy.
    Manzella L; Department of Clinical and Experimental Medicine, University of Catania, Catania I-95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, Catania I-95123, Italy.
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    Źródło:
    Oncology letters [Oncol Lett] 2019 Sep; Vol. 18 (3), pp. 2648-2653. Date of Electronic Publication: 2019 Jul 04.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Activation of the IGF Axis in Thyroid Cancer: Implications for Tumorigenesis and Treatment.
    Autorzy:
    Manzella L; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy. .; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy. .
    Massimino M; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy.
    Stella S; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy.
    Tirrò E; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy.
    Pennisi MS; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy.
    Martorana F; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy.; Department of Medical Oncology A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy.
    Motta G; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy.; Department of Medical Oncology A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy.
    Vitale SR; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy.
    Puma A; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy.
    Romano C; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy.
    Di Gregorio S; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy.
    Russo M; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Medical Center, University of Catania, 95122, Italy.
    Malandrino P; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Medical Center, University of Catania, 95122, Italy.
    Vigneri P; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico-Vittorio Emanuele, 95123 Catania, Italy.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2019 Jul 02; Vol. 20 (13). Date of Electronic Publication: 2019 Jul 02.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Signal Transduction*/drug effects
    Carcinogenesis/*metabolism
    Somatomedins/*metabolism
    Thyroid Neoplasms/*metabolism
    Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Carcinogenesis/drug effects ; Carcinogenesis/pathology ; Humans ; Molecular Targeted Therapy ; Thyroid Neoplasms/drug therapy ; Thyroid Neoplasms/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Clinical Implications of Discordant Early Molecular Responses in CML Patients Treated with Imatinib.
    Autorzy:
    Stella S; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy. .; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, 95123 Catania, Italy. .
    Zammit V; Division of Hematology and Bone Marrow Transplant, AOU Policlinico - V. Emanuele, 95123 Catania, Italy. .
    Vitale SR; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy. .; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, 95123 Catania, Italy. .
    Pennisi MS; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy. .; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, 95123 Catania, Italy. .
    Massimino M; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy. .; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, 95123 Catania, Italy. .
    Tirrò E; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy. ele_.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, 95123 Catania, Italy. ele_.
    Forte S; Mediterranean Institute of Oncology, 95029 Viagrande, Italy. .
    Spitaleri A; Division of Hematology and Bone Marrow Transplant, AOU Policlinico - V. Emanuele, 95123 Catania, Italy. .
    Antolino A; Department of Transfusional Medicine, Maria Paternò-Arezzo Hospital, 97100 Ragusa, Italy. .
    Siracusa S; Division of Hematology, A.O.U. Policlinico 'P. Giaccone', University of Palermo, 90127 Palermo, Italy. .
    Accurso V; Division of Hematology, A.O.U. Policlinico 'P. Giaccone', University of Palermo, 90127 Palermo, Italy. .
    Mannina D; Division of Hematology, Papardo Hospital, 98158 Messina, Italy. .
    Impera S; Division of Oncology and Hematology, ARNAS Garibaldi-Nesima, 95122 Catania, Italy. .
    Musolino C; Division of Hematology, University of Messina, 98125 Messina, Italy. .
    Russo S; Division of Hematology, University of Messina, 98125 Messina, Italy. .
    Malato A; Division of Hematology and Bone Marrow Transplant, Villa Sofia-Cervello Hospital, 90146 Palermo, Italy. .
    Mineo G; Division of Hematology, San Vincenzo Hospital, 98039 Taormina, Italy. .
    Musso M; Division of Hematology, La Maddalena Hospital, 90146 Palermo, Italy. .
    Porretto F; Division of Hematology, La Maddalena Hospital, 90146 Palermo, Italy. .
    Martino B; Hematology Department, Grande Ospedale Metropolitano, Reggio Calabria, 89124 Reggio Calabria, Italy. .
    Di Raimondo F; Division of Hematology and Bone Marrow Transplant, AOU Policlinico - V. Emanuele, 95123 Catania, Italy. .; Department of Surgery, Medical and Surgical Specialities, University of Catania, 95123 Catania, Italy. .
    Manzella L; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy. .; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, 95123 Catania, Italy. .
    Vigneri P; Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy. .; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, 95123 Catania, Italy. .
    Stagno F; Division of Hematology and Bone Marrow Transplant, AOU Policlinico - V. Emanuele, 95123 Catania, Italy. .
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2019 May 06; Vol. 20 (9). Date of Electronic Publication: 2019 May 06.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Antineoplastic Agents/*therapeutic use
    Biomarkers, Tumor/*genetics
    Fusion Proteins, bcr-abl/*genetics
    Imatinib Mesylate/*therapeutic use
    Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
    Protein Kinase Inhibitors/*therapeutic use
    Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/metabolism ; Female ; Fusion Proteins, bcr-abl/antagonists & inhibitors ; Fusion Proteins, bcr-abl/metabolism ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Male ; Middle Aged ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Non ABL-directed inhibitors as alternative treatment strategies for chronic myeloid leukemia.
    Autorzy:
    Massimino M; Department of Clinical and Experimental Medicine, University of Catania, Via Santa Sofia, 78, Catania, 95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, Via Santa Sofia, 78, 95123, Catania, Italy.
    Stella S; Department of Clinical and Experimental Medicine, University of Catania, Via Santa Sofia, 78, Catania, 95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, Via Santa Sofia, 78, 95123, Catania, Italy.
    Tirrò E; Department of Clinical and Experimental Medicine, University of Catania, Via Santa Sofia, 78, Catania, 95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, Via Santa Sofia, 78, 95123, Catania, Italy.
    Romano C; Department of Clinical and Experimental Medicine, University of Catania, Via Santa Sofia, 78, Catania, 95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, Via Santa Sofia, 78, 95123, Catania, Italy.
    Pennisi MS; Department of Clinical and Experimental Medicine, University of Catania, Via Santa Sofia, 78, Catania, 95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, Via Santa Sofia, 78, 95123, Catania, Italy.
    Puma A; Department of Clinical and Experimental Medicine, University of Catania, Via Santa Sofia, 78, Catania, 95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, Via Santa Sofia, 78, 95123, Catania, Italy.
    Manzella L; Department of Clinical and Experimental Medicine, University of Catania, Via Santa Sofia, 78, Catania, 95123, Italy.; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, Via Santa Sofia, 78, 95123, Catania, Italy.
    Zanghì A; Department of Surgical Medical Sciences and Advanced Technologies, University of Catania, Via Santa Sofia, 78, Catania, 95123, Italy.
    Stagno F; Division of Hematology and Bone Marrow Transplant, University of Catania, Via Santa Sofia, 78, Catania, 95123, Italy.
    Di Raimondo F; Division of Hematology and Bone Marrow Transplant, University of Catania, Via Santa Sofia, 78, Catania, 95123, Italy.; Department of Surgery, Medical and Surgical Specialties, University of Catania, Via Santa Sofia, 78, Catania, 95123, Italy.
    Vigneri P; Department of Clinical and Experimental Medicine, University of Catania, Via Santa Sofia, 78, Catania, 95123, Italy. .; Center of Experimental Oncology and Hematology, A.O.U. Policlinico Vittorio Emanuele, Via Santa Sofia, 78, 95123, Catania, Italy. .
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    Źródło:
    Molecular cancer [Mol Cancer] 2018 Feb 19; Vol. 17 (1), pp. 56. Date of Electronic Publication: 2018 Feb 19.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Review
    MeSH Terms:
    Biomarkers, Tumor*
    Molecular Targeted Therapy*
    Antineoplastic Agents/*pharmacology
    Antineoplastic Agents/*therapeutic use
    Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
    Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*metabolism
    Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Combined Modality Therapy ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology ; Signal Transduction/drug effects ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    New Insights in Thyroid Cancer and p53 Family Proteins.
    Autorzy:
    Manzella L; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy. .
    Stella S; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy. .
    Pennisi MS; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy. .
    Tirrò E; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy. ele_.
    Massimino M; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy. .
    Romano C; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy. .
    Puma A; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy. .
    Tavarelli M; Endocrinology, Department of Clinical and Experimental Medicine, Garibaldi Nesima Medical Center, University of Catania, 95122 Catania, Italy. .
    Vigneri P; Department of Clinical and Experimental Medicine, University of Catania, 95124 Catania, Italy. .
    Pokaż więcej
    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2017 Jun 21; Vol. 18 (6). Date of Electronic Publication: 2017 Jun 21.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Thyroid Neoplasms/*genetics
    Tumor Suppressor Protein p53/*genetics
    Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Humans ; Molecular Targeted Therapy/methods ; Mutation/drug effects ; Signal Transduction/drug effects ; Thyroid Gland/drug effects ; Thyroid Gland/metabolism ; Thyroid Gland/pathology ; Thyroid Neoplasms/drug therapy ; Thyroid Neoplasms/metabolism ; Thyroid Neoplasms/pathology ; Tumor Suppressor Protein p53/analysis ; Tumor Suppressor Protein p53/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Concomitant and feasible treatment with dasatinib and the anti-EGFR antibody cetuximab plus radiotherapy in a CML patient with multiple squamous neoplasias.
    Autorzy:
    Stagno F; Department of Biomedical Sciences, Section of Hematology, University of Catania, Italy. />Vigneri P
    Del Fabro V
    Stella S
    Restuccia N
    Giallongo C
    Massimino M
    Berretta S
    Pennisi MS
    Tibullo D
    Tirrò E
    Buscarino C
    Messina A
    Di Raimondo F
    Pokaż więcej
    Źródło:
    Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2010; Vol. 49 (1), pp. 109-10.
    Typ publikacji:
    Case Reports; Journal Article
    MeSH Terms:
    Radiotherapy*
    Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
    Carcinoma, Squamous Cell/*therapy
    Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*therapy
    Neoplasms, Second Primary/*therapy
    Adult ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Monoclonal, Humanized ; Carcinoma/pathology ; Carcinoma/therapy ; Carcinoma, Squamous Cell/pathology ; Cetuximab ; Combined Modality Therapy ; Dasatinib ; Ear Diseases/pathology ; Ear Diseases/therapy ; Fusion Proteins, bcr-abl/genetics ; Humans ; Keratoacanthoma/pathology ; Keratoacanthoma/therapy ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology ; Male ; Neoplasms, Second Primary/pathology ; Pyrimidines/administration & dosage ; Scalp/pathology ; Thiazoles/administration & dosage ; Tongue Neoplasms/pathology ; Vocal Cords/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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