Temat: "Peptidases" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Identification of an Additional Metal-Binding Site in Human Dipeptidyl Peptidase III.
Autorzy:: Matić A; Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.
Šupljika F; Department of Chemistry and Biochemistry, Faculty of Food Technology and Biotechnology, Pierottijeva 6, 10000 Zagreb, Croatia.
Brkić H; Faculty of Medicine, J. J. Strossmayer University of Osijek, 31000 Osijek, Croatia.; Faculty of Dental Medicine and Health, J. J. Strossmayer University of Osijek, 31000 Osijek, Croatia.
Jurasović J; Analytical Toxicology and Mineral Metabolism Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Karačić Z; Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.
Tomić S; Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 13; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 13.
Typ publikacji:: Journal Article
MeSH Terms:: Dipeptidyl-Peptidases and Tripeptidyl-Peptidases*
Humans ; Binding Sites ; Catalytic Domain ; Protein Domains

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Skocz do pozycji: 2.

Tytuł:: Prostaglandin Transporter and Dipeptidyl Peptidase-4 as New Pharmacological Targets in the Prevention of Acute Kidney Injury in Diabetes: An In Vitro Study.
Autorzy:: Gallego-Tamayo B; Universidad de Alcalá, Departamento de Biología de Sistemas, Facultad de Medicina y Ciencias de la Salud, Campus Universitario, Crtra A2, Km. 33,600, 28805 Alcalá de Henares, Spain.
Santos-Aparicio Á; Universidad de Alcalá, Departamento de Biología de Sistemas, Facultad de Medicina y Ciencias de la Salud, Campus Universitario, Crtra A2, Km. 33,600, 28805 Alcalá de Henares, Spain.
Yago-Ibáñez J; Departamento de Biología, Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Muñoz-Moreno L; Universidad de Alcalá, Departamento de Biología de Sistemas, Facultad de Medicina y Ciencias de la Salud, Campus Universitario, Crtra A2, Km. 33,600, 28805 Alcalá de Henares, Spain.
Lucio-Cazaña FJ; Universidad de Alcalá, Departamento de Biología de Sistemas, Facultad de Medicina y Ciencias de la Salud, Campus Universitario, Crtra A2, Km. 33,600, 28805 Alcalá de Henares, Spain.
Fernández-Martínez AB; Departamento de Biología, Universidad Autónoma de Madrid, 28049 Madrid, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 15; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus*/drug therapy
Acute Kidney Injury*/drug therapy
Acute Kidney Injury*/etiology
Acute Kidney Injury*/prevention & control
Dipeptidyl-Peptidase IV Inhibitors*/pharmacology
Dipeptidyl-Peptidase IV Inhibitors*/therapeutic use
Humans ; Cyclooxygenase 2/metabolism ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases ; Prostaglandins ; Dipeptidyl Peptidase 4

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Skocz do pozycji: 3.

Tytuł:: Healthcare resource utilization and healthcare costs in patients with type 2 diabetes mellitus initiating sodium-glucose cotransporter 2 inhibitors vs dipeptidyl peptidase-4 inhibitors in Japan: A real-world administrative database analysis.
Autorzy:: Kashiwagi A; Department of Diabetes and Endocrinology, Omi Medical Center, Kusatsu, Shiga, Japan.
Shoji S; Medical Affairs, Astellas Pharma Inc., Tokyo, Japan.
Kosakai Y; Medical Affairs, Astellas Pharma Inc., Tokyo, Japan.
Yoshinaga Y; Data Science, Astellas Pharma Inc., Tokyo, Japan.
Rokuda M; Medical Affairs, Astellas Pharma Inc., Tokyo, Japan.; Pokaż więcej
Źródło:: Journal of diabetes investigation [J Diabetes Investig] 2024 Mar; Vol. 15 (3), pp. 374-387. Date of Electronic Publication: 2023 Dec 19.
Typ publikacji:: Journal Article
MeSH Terms:: Dipeptidyl-Peptidase IV Inhibitors*/therapeutic use
Diabetes Mellitus, Type 2*/drug therapy
Humans ; Japan/epidemiology ; Retrospective Studies ; Health Care Costs ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases ; Glucose ; Sodium

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Skocz do pozycji: 4.

Tytuł:: Efficacy and Safety of Omarigliptin, a Novel Once-Weekly Dipeptidyl Peptidase-4 Inhibitor, in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.
Autorzy:: Kamrul-Hasan ABM; Department of Endocrinology, Mymensingh Medical College, Mymensingh, Bangladesh.
Alam MS; Department of Medicine, Army Medical College Cumilla, Cumilla, Bangladesh.
Talukder SK; Department of Endocrinology, Rangpur Medical College, Rangpur, Bangladesh.
Dutta D; Department of Endocrinology, Center for Endocrinology, Diabetes, Arthritis and Rheumatism (CEDAR) Superspeciality Healthcare, New Delhi, India.
Selim S; Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.; Pokaż więcej
Źródło:: Endocrinology and metabolism (Seoul, Korea) [Endocrinol Metab (Seoul)] 2024 Feb; Vol. 39 (1), pp. 109-126. Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:: Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:: Dipeptidyl-Peptidase IV Inhibitors*/adverse effects
Diabetes Mellitus, Type 2*/complications
Hypoglycemia*/chemically induced
Hypoglycemia*/epidemiology
Heterocyclic Compounds, 2-Ring*
Pyrans*
Humans ; Glycated Hemoglobin ; Blood Glucose/analysis ; Hypoglycemic Agents/adverse effects ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/therapeutic use

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Skocz do pozycji: 5.

Tytuł:: Use of dipeptidyl peptidase-4 inhibitors was associated with a lower risk of Parkinson's disease in diabetic patients.
Autorzy:: Lin YH; Division of Neurology, Neurological Institute, Taichung Veterans General Hospital, 1650 Taiwan Boulevard Sect. 4, Taichung, 40705, Taiwan.
Hsu CC; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan.; National Center for Geriatrics and Welfare Research, National Health Research Institutes, Yunlin, Taiwan.; Department of Family Medicine, Min-Sheng General Hospital, Taoyuan, 33044, Taiwan.
Liu JS; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan.; National Center for Geriatrics and Welfare Research, National Health Research Institutes, Yunlin, Taiwan.
Chang KC; Division of Neurology, Neurological Institute, Taichung Veterans General Hospital, 1650 Taiwan Boulevard Sect. 4, Taichung, 40705, Taiwan. .
Huang JA; Division of Neurology, Neurological Institute, Taichung Veterans General Hospital, 1650 Taiwan Boulevard Sect. 4, Taichung, 40705, Taiwan. .; Department of Health Business Administration, Hungkuang University, Taichung, 43302, Taiwan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Dec 15; Vol. 13 (1), pp. 22489. Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:: Journal Article
MeSH Terms:: Dipeptidyl-Peptidase IV Inhibitors*/therapeutic use
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/epidemiology
Parkinson Disease*/drug therapy
Parkinson Disease*/epidemiology
Parkinson Disease*/complications
Metformin*/therapeutic use
Humans ; Cohort Studies ; Hypoglycemic Agents/therapeutic use ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases ; Dipeptidyl Peptidase 4

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Skocz do pozycji: 6.

Tytuł:: Dipeptidyl peptidase-4 inhibitors alleviate cognitive dysfunction in type 2 diabetes mellitus.
Autorzy:: Meng J; Department of Pathology, Beijing TongRen Hospital, Capital Medical University, Beijing, China.; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Yan R; Center for Movement Disorders, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhang C; National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Bai X; Department of Hemotology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yang X; Department of Cardiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yang Y; Department of Cardiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Feng T; Center for Movement Disorders, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. .; National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. .
Liu X; Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. .; Pokaż więcej
Źródło:: Lipids in health and disease [Lipids Health Dis] 2023 Dec 11; Vol. 22 (1), pp. 219. Date of Electronic Publication: 2023 Dec 11.
Typ publikacji:: Systematic Review; Journal Article
MeSH Terms:: Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/drug therapy
Dipeptidyl-Peptidase IV Inhibitors*/pharmacology
Dipeptidyl-Peptidase IV Inhibitors*/therapeutic use
Cognitive Dysfunction*/drug therapy
Humans ; Activities of Daily Living ; Hypoglycemic Agents/therapeutic use ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/therapeutic use

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Skocz do pozycji: 7.

Tytuł:: Once-weekly glucagon-like peptide-1 receptor agonists vs dipeptidyl peptidase-4 inhibitors: cardiovascular effects in people with diabetes and cardiovascular disease.
Autorzy:: Tan X; Novo Nordisk Inc., Plainsboro, NJ, USA.
Liang Y; Novo Nordisk Inc., Plainsboro, NJ, USA.
Rajpura JR; Novo Nordisk Inc., Plainsboro, NJ, USA.
Yedigarova L; Novo Nordisk Inc., Plainsboro, NJ, USA.
Noone J; Novo Nordisk Inc., Plainsboro, NJ, USA.
Xie L; Novo Nordisk Inc., Plainsboro, NJ, USA.
Inzucchi S; Department of Endocrinology, Yale University, New Haven, CT, USA.
de Havenon A; Department of Neurology, Center for Brain and Mind Health, Yale School of Medicine, Yale University, 15 York St, New Haven, CT, 06510, USA. .; Pokaż więcej
Źródło:: Cardiovascular diabetology [Cardiovasc Diabetol] 2023 Nov 20; Vol. 22 (1), pp. 319. Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:: Observational Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dipeptidyl-Peptidase IV Inhibitors*/adverse effects
Diabetes Mellitus, Type 2*/diagnosis
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/epidemiology
Cardiovascular Diseases*/diagnosis
Cardiovascular Diseases*/epidemiology
Cardiovascular Diseases*/prevention & control
Myocardial Infarction*/diagnosis
Myocardial Infarction*/epidemiology
Myocardial Infarction*/complications
Ischemic Stroke*
Adult ; Humans ; Glucagon-Like Peptide-1 Receptor/agonists ; Risk Factors ; Glucagon-Like Peptide 1/therapeutic use ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/therapeutic use ; Hypoglycemic Agents/adverse effects

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Skocz do pozycji: 8.

Tytuł:: Effect of dipeptidyl peptidase-4 inhibitor on the progression of coronary artery disease evaluated by computed tomography in patients receiving insulin therapy for type 2 diabetes mellitus.
Autorzy:: Choi Y; Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.; Cardiovascular Research Institute for Intractable Disease, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Ko SH; Division of Endocrinology and Metabolism, Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Chang K; Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.; Cardiovascular Research Institute for Intractable Disease, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Yoo KD; Cardiovascular Research Institute for Intractable Disease, College of Medicine, The Catholic University of Korea, Seoul, South Korea.; Division of Cardiology, Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Ihm SH; Cardiovascular Research Institute for Intractable Disease, College of Medicine, The Catholic University of Korea, Seoul, South Korea.; Division of Cardiology, Department of Internal Medicine, Bucheon St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea.; Pokaż więcej
Źródło:: Journal of diabetes [J Diabetes] 2023 Nov; Vol. 15 (11), pp. 944-954. Date of Electronic Publication: 2023 Aug 01.
Typ publikacji:: Multicenter Study; Journal Article
MeSH Terms:: Diabetes Mellitus, Type 2*/epidemiology
Dipeptidyl-Peptidase IV Inhibitors*/therapeutic use
Coronary Artery Disease*/diagnostic imaging
Coronary Artery Disease*/drug therapy
Humans ; Insulin/therapeutic use ; Hypoglycemic Agents/therapeutic use ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/therapeutic use ; Tomography

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Skocz do pozycji: 9.

Tytuł:: Integration of Deep Learning and Sequential Metabolism to Rapidly Screen Dipeptidyl Peptidase (DPP)-IV Inhibitors from Gardenia jasminoides Ellis .
Autorzy:: Liu H; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Yu S; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Li X; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Wang X; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Qi D; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Pan F; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Chai X; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Wang Q; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Pan Y; Institute of Information on Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Zhang L; Institute of Medical Innovation and Research, Peking University Third Hospital, Beijing 100191, China.
Liu Y; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Nov 01; Vol. 28 (21). Date of Electronic Publication: 2023 Nov 01.
Typ publikacji:: Journal Article
MeSH Terms:: Dipeptidyl-Peptidase IV Inhibitors*/pharmacology
Gardenia*/chemistry
Deep Learning*
Iridoid Glycosides/chemistry ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases ; Dipeptidyl Peptidase 4 ; Molecular Docking Simulation

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Skocz do pozycji: 10.

Tytuł:: Neuronal Roles of the Multifunctional Protein Dipeptidyl Peptidase-like 6 (DPP6).
Autorzy:: Malloy C; Molecular Neurophysiology and Biophysics Section, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Ahern M; Molecular Neurophysiology and Biophysics Section, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Lin L; Molecular Neurophysiology and Biophysics Section, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Hoffman DA; Molecular Neurophysiology and Biophysics Section, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Aug 16; Vol. 23 (16). Date of Electronic Publication: 2022 Aug 16.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Dipeptidyl-Peptidases and Tripeptidyl-Peptidases*/genetics
Dipeptidyl-Peptidases and Tripeptidyl-Peptidases*/metabolism
Shal Potassium Channels*/metabolism
Kv Channel-Interacting Proteins/metabolism ; Nerve Tissue Proteins/metabolism ; Neurons/metabolism

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Skocz do pozycji: 11.

Tytuł:: Empagliflozin is associated with lower cardiovascular risk compared with dipeptidyl peptidase-4 inhibitors in adults with and without cardiovascular disease: EMPagliflozin compaRative effectIveness and SafEty (EMPRISE) study results from Europe and Asia.
Autorzy:: Vistisen D; Steno Diabetes Center Copenhagen, Copenhagen, Denmark.; Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Carstensen B; Steno Diabetes Center Copenhagen, Copenhagen, Denmark.
Elisabetta P; Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Lanzinger S; Institute for Epidemiology and Medical Biometry, ZIBMT, Ulm University, Ulm, Germany.; German Centre for Diabetes Research (DZD), Munich-Neuherberg, Germany.
Tan EC; Department of Health Service Administration, China Medical University, Taichung, Taiwan.
Yabe D; Yutaka Seino Distinguished Centre for Diabetes Research, Kansai Electric Power Medical Research Institute, Kobe, Japan.; Department of Diabetes, Metabolism and Endocrinology/Department of Rheumatology and Clinical Immunology, Gifu University Graduate School of Medicine, Gifu, Japan.; Center for Healthcare Information Technology, Tokai National Higher Education and Research System, Nagoya, Japan.; Preemptive Food Research Centre, Gifu University Institute for Advanced Study, Gifu, Japan.
Kim DJ; Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, South Korea.
Sheu WH; Insititute of Molecular and Genomic Medicine, National Health Research Institutes, Taipei City, Taiwan.
Melzer-Cohen C; Maccabi Institute for Research and Innovation, Maccabi Healthcare Services, Tel-Aviv, Israel.
Holl RW; Institute for Epidemiology and Medical Biometry, ZIBMT, Ulm University, Ulm, Germany.
Núñez J; Department of Cardiology, Hospital Clínico Universitario de Valencia, INCLIVA, Universidad de Valencia, CIBER Cardiovascular, Valencia, Spain.
Ha KH; Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, South Korea.
Halvorsen S; Department of Cardiology, Oslo University Hospital Ullevål, University of Oslo, Oslo, Norway.
Langslet G; Department of Endocrinology, Morbid Obesity and Preventive Medicine, Lipid Clinic, Oslo University Hospital, Oslo, Norway.
Karasik A; Maccabi Institute for Research and Innovation, Maccabi Healthcare Services, Tel-Aviv, Israel.
Nyström T; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Niskanen L; Päijät-Häme Joint Authority for Health and Wellbeing, Päijät-Häme Central Hospital, Lahti, Finland.; University of Eastern Finland, Kuopio, Finland.
Guleria S; IQVIA, Goteborg, Sweden.
Klement R; IQVIA, Tartu, Estonia.
Carrasco M; Boehringer Ingelheim Pharmaceuticals, Inc., Barcelona, Spain.
Foersch J; Boehringer Ingelheim International GmbH, Ingelheim, Germany.
Shay C; Boehringer Ingelheim Pharmaceuticals USA, 00 Ridgebury Road, Ridgefield, CT, 06877, USA. .
Koeneman L; Lilly Deutschland GmbH, Bad Homburg, Germany.
Hoti F; IQVIA, Espoo, Finland.
Farsani SF; Boehringer Ingelheim International GmbH, Ingelheim, Germany.
Khunti K; Leicester Real World Evidence Unit, Leicester Diabetes Centre, University of Leicester, Leicester, UK.
Zaccardi F; Leicester Real World Evidence Unit, Leicester Diabetes Centre, University of Leicester, Leicester, UK.
Subramanian A; Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
Nirantharakumar K; Institute of Applied Health Research, University of Birmingham, Birmingham, UK.; Midlands Health Data Research UK, Birmingham, UK.; DEMAND Hub, University of Birmingham, Birmingham, UK.; Pokaż więcej
Corporate Authors:: EMPRISE EU
East Asia Study Group
Źródło:: Cardiovascular diabetology [Cardiovasc Diabetol] 2023 Aug 31; Vol. 22 (1), pp. 233. Date of Electronic Publication: 2023 Aug 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cardiovascular Diseases*/diagnosis
Cardiovascular Diseases*/epidemiology
Cardiovascular Diseases*/prevention & control
Diabetes Mellitus, Type 2*/diagnosis
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/epidemiology
Dipeptidyl-Peptidase IV Inhibitors*/adverse effects
Sodium-Glucose Transporter 2 Inhibitors*/adverse effects
Heart Failure*
Myocardial Infarction*
Stroke*/diagnosis
Stroke*/epidemiology
Stroke*/prevention & control
Humans ; Adult ; Risk Factors ; Asia/epidemiology ; Europe/epidemiology ; Heart Disease Risk Factors ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases

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Skocz do pozycji: 12.

Tytuł:: Contribution of dipeptidyl peptidase 10 to airway dysfunction in patients with NSAID-exacerbated respiratory disease.
Autorzy:: Sim S; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.; Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Korea.
Choi Y; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
Lee DH; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
Lee HR; MD Healthcare Inc, Seoul, Korea.
Seob Shin Y; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
Park HS; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.; Pokaż więcej
Źródło:: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2022 Jan; Vol. 52 (1), pp. 115-126. Date of Electronic Publication: 2021 Aug 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Asthma*/metabolism
Respiratory Tract Diseases*/pathology
Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/*metabolism
Animals ; Anti-Inflammatory Agents, Non-Steroidal ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/genetics ; Humans ; Lung/metabolism ; Mice ; Transforming Growth Factor beta1

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Skocz do pozycji: 13.

Tytuł:: Molecular Dynamics Simulations Study of the Interactions between Human Dipeptidyl-Peptidase III and Two Substrates.
Autorzy:: Zhang S; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
Lv S; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
Fu X; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
Han L; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
Han W; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
Li W; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Oct 27; Vol. 26 (21). Date of Electronic Publication: 2021 Oct 27.
Typ publikacji:: Journal Article
MeSH Terms:: Molecular Docking Simulation*
Molecular Dynamics Simulation*
Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/*chemistry
Binding Sites ; Catalysis ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/metabolism ; Humans ; Hydrogen Bonding ; Hydrophobic and Hydrophilic Interactions ; Ligands ; Protease Inhibitors/chemistry ; Protease Inhibitors/pharmacology ; Protein Binding ; Protein Conformation ; Structure-Activity Relationship ; Substrate Specificity

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Skocz do pozycji: 14.

Tytuł:: Dose selection for intracerebroventricular cerliponase alfa in children with CLN2 disease, translation from animal to human in a rare genetic disease.
Autorzy:: Hammon K; BioMarin Pharmaceutical Inc., Novato, California, USA.
de Hart G; BioMarin Pharmaceutical Inc., Novato, California, USA.
Vuillemenot BR; BioMarin Pharmaceutical Inc., Novato, California, USA.
Kennedy D; BioMarin Pharmaceutical Inc., Novato, California, USA.
Musson D; BioMarin Pharmaceutical Inc., Novato, California, USA.
O'Neill CA; BioMarin Pharmaceutical Inc., Novato, California, USA.
Katz ML; Mason Eye Institute, University of Missouri School of Medicine, Columbia, Missouri, USA.; Department of Bioengineering, University of Missouri, Columbia, Missouri, USA.
Henshaw JW; BioMarin Pharmaceutical Inc., Novato, California, USA.; Pokaż więcej
Źródło:: Clinical and translational science [Clin Transl Sci] 2021 Sep; Vol. 14 (5), pp. 1810-1821. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji:: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/*administration & dosage
Enzyme Replacement Therapy/*methods
Neuronal Ceroid-Lipofuscinoses/*drug therapy
Rare Diseases/*drug therapy
Recombinant Proteins/*administration & dosage
Tripeptidyl-Peptidase 1/*deficiency
Animals ; Child ; Child, Preschool ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/pharmacokinetics ; Disease Models, Animal ; Disease Progression ; Dogs ; Drug Administration Schedule ; Drug Dosage Calculations ; Female ; Humans ; Infusions, Intraventricular ; Macaca fascicularis ; Male ; Neuronal Ceroid-Lipofuscinoses/cerebrospinal fluid ; Neuronal Ceroid-Lipofuscinoses/genetics ; Rare Diseases/genetics ; Recombinant Proteins/pharmacokinetics ; Treatment Outcome ; Tripeptidyl-Peptidase 1/genetics
SCR Disease Name:: Ceroid Lipofuscinosis, Neuronal, 2

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Skocz do pozycji: 15.

Tytuł:: Risk heterogeneity of bullous pemphigoid among dipeptidyl peptidase-4 inhibitors: A population-based cohort study using Japanese Latter-Stage Elderly Healthcare Database.
Autorzy:: Harano Y; Department of Health Care Administration and Management, Graduate School of Medical Sciences, Kyushu University, Fukuoka City, Fukuoka, Japan.; Department of General Internal Medicine, Local Incorporated Administrative Agency Saga-Ken Medical Centre Koseikan, Saga, Japan.
Mitamura Y; Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka City, Fukuoka, Japan.
Jiang P; Department of Health Care Administration and Management, Graduate School of Medical Sciences, Kyushu University, Fukuoka City, Fukuoka, Japan.
Fujita T; Department of Health Care Administration and Management, Graduate School of Medical Sciences, Kyushu University, Fukuoka City, Fukuoka, Japan.; Department of Health Sciences, Faculty of Medical Sciences, Kyushu University, Fukuoka City, Fukuoka, Japan.
Babazono A; Department of Health Care Administration and Management, Graduate School of Medical Sciences, Kyushu University, Fukuoka City, Fukuoka, Japan.; Pokaż więcej
Źródło:: Journal of diabetes investigation [J Diabetes Investig] 2023 Jun; Vol. 14 (6), pp. 756-766. Date of Electronic Publication: 2023 Mar 10.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Dipeptidyl-Peptidase IV Inhibitors*/adverse effects
Dipeptidyl-Peptidase IV Inhibitors*/therapeutic use
Pemphigoid, Bullous*/chemically induced
Pemphigoid, Bullous*/epidemiology
Aged ; Humans ; Cohort Studies ; Delivery of Health Care ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/therapeutic use ; East Asian People ; Hypoglycemic Agents/therapeutic use ; Linagliptin/adverse effects ; Retrospective Studies ; Sitagliptin Phosphate/adverse effects ; Vildagliptin

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Skocz do pozycji: 16.

Tytuł:: Extracellular Vesicles Released by Genetically Modified Macrophages Activate Autophagy and Produce Potent Neuroprotection in Mouse Model of Lysosomal Storage Disorder, Batten Disease.
Autorzy:: El-Hage N; Department of Immunology and Nanomedicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Haney MJ; Center for Nanotechnology in Drug Delivery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Zhao Y; Center for Nanotechnology in Drug Delivery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Rodriguez M; Department of Immunology and Nanomedicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Wu Z; Department of Radiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
Liu M; Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Swain CJ; Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Yuan H; Department of Radiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
Batrakova EV; Center for Nanotechnology in Drug Delivery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2023 May 29; Vol. 12 (11). Date of Electronic Publication: 2023 May 29.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Neuronal Ceroid-Lipofuscinoses*/metabolism
Lysosomal Storage Diseases*/metabolism
Extracellular Vesicles*/metabolism
Mice ; Animals ; Serine Proteases/genetics ; Aminopeptidases/genetics ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/metabolism ; Lipofuscin/metabolism ; Lipofuscin/therapeutic use ; Neuroprotection ; Tripeptidyl-Peptidase 1 ; Lysosomes/metabolism ; Autophagy
SCR Disease Name:: Ceroid Lipofuscinosis, Neuronal, 2

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Skocz do pozycji: 17.

Tytuł:: Dipeptidyl peptidase-1 inhibition with brensocatib reduces the activity of all major neutrophil serine proteases in patients with bronchiectasis: results from the WILLOW trial.
Autorzy:: Cipolla D; Insmed Incorporated, 700 US Highway 202/206, Bridgewater, NJ, 08807, USA. .
Zhang J; Insmed Incorporated, 700 US Highway 202/206, Bridgewater, NJ, 08807, USA.
Korkmaz B; INSERM UMR-1100, 'Research Center for Respiratory Diseases' and University of Tours, Tours, France.
Chalmers JD; Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
Basso J; Insmed Incorporated, 700 US Highway 202/206, Bridgewater, NJ, 08807, USA.
Lasala D; Insmed Incorporated, 700 US Highway 202/206, Bridgewater, NJ, 08807, USA.
Fernandez C; Insmed Incorporated, 700 US Highway 202/206, Bridgewater, NJ, 08807, USA.
Teper A; Insmed Incorporated, 700 US Highway 202/206, Bridgewater, NJ, 08807, USA.
Mange KC; Insmed Incorporated, 700 US Highway 202/206, Bridgewater, NJ, 08807, USA.
Perkins WR; Insmed Incorporated, 700 US Highway 202/206, Bridgewater, NJ, 08807, USA.
Sullivan EJ; Insmed Incorporated, 700 US Highway 202/206, Bridgewater, NJ, 08807, USA.; Pokaż więcej
Źródło:: Respiratory research [Respir Res] 2023 May 17; Vol. 24 (1), pp. 133. Date of Electronic Publication: 2023 May 17.
Typ publikacji:: Randomized Controlled Trial; Journal Article
MeSH Terms:: Salix*
Bronchiectasis*/diagnosis
Bronchiectasis*/drug therapy
Cystic Fibrosis*
Humans ; Serine Proteases/pharmacology ; Serine Proteases/therapeutic use ; Neutrophils ; Leukocyte Elastase ; Myeloblastin ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/pharmacology ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/therapeutic use

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Skocz do pozycji: 18.

Tytuł:: Dipeptidyl peptidase III as a DNA marker to investigate epidemiology and taxonomy of Old World Leishmania species.
Autorzy:: Bel Hadj Ali I; Laboratory of Molecular Epidemiology and Experimental Pathology, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunisia.
Chouaieb H; Laboratory of Molecular Epidemiology and Experimental Pathology, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunisia.; Service de parasitologie, EPS Farhat Hached, Faculté de Médecine de Sousse, Université de Sousse, Sousse, Tunisia.
Saadi Ben Aoun Y; Laboratory of Molecular Epidemiology and Experimental Pathology, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunisia.
Harigua-Souiai E; Laboratory of Molecular Epidemiology and Experimental Pathology, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunisia.
Souguir H; Laboratory of Molecular Epidemiology and Experimental Pathology, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunisia.
Yaacoub A; Laboratory of Molecular Epidemiology and Experimental Pathology, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunisia.; Service de parasitologie, EPS Farhat Hached, Faculté de Médecine de Sousse, Université de Sousse, Sousse, Tunisia.
El Dbouni O; Department of Infectious Diseases, Rafik Hariri Hospital, Beirut, Lebanon.
Harrat Z; Laboratoire d'Eco-épidémiologie Parasitaire et Génétique des Populations, Institut Pasteur d'Algérie, Algiers, Algeria.
Mukhtar MM; Bioscience Research Institute, Ibn Sina University, Khartoum, Sudan.
Ben Said M; Service de parasitologie, EPS Farhat Hached, Faculté de Médecine de Sousse, Université de Sousse, Sousse, Tunisia.
Haddad N; Laboratory of Immunology and Vector-Borne Diseases, Faculty of Public Health Lebanese University, Hadath, Lebanon.
Fathallah-Mili A; Laboratory of Molecular Epidemiology and Experimental Pathology, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunisia.; Service de parasitologie, EPS Farhat Hached, Faculté de Médecine de Sousse, Université de Sousse, Sousse, Tunisia.
Guizani I; Laboratory of Molecular Epidemiology and Experimental Pathology, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunisia.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Jul 26; Vol. 15 (7), pp. e0009530. Date of Electronic Publication: 2021 Jul 26 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/*genetics
Leishmania/*enzymology
Leishmaniasis, Cutaneous/*parasitology
Protozoan Proteins/*genetics
DNA Primers/genetics ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/metabolism ; Genetic Markers ; Humans ; Leishmania/classification ; Leishmania/genetics ; Leishmania/isolation & purification ; Leishmaniasis, Cutaneous/epidemiology ; Phylogeny ; Polymerase Chain Reaction ; Protozoan Proteins/metabolism

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Skocz do pozycji: 19.

Tytuł:: Identification and heterologous expression of the globomycin biosynthetic gene cluster.
Autorzy:: Oves-Costales, Daniel
Gren, Tetiana
Sterndorff, Eva Baggesgaard
Martín, Jesús
Ortiz-López, Francisco Javier
Jørgensen, Tue S.
Xinglin Jiang
Román-Hurtado, Fernando
Reyes, Fernando
Genilloud, Olga
Weber, Tilmann; Pokaż więcej
Źródło:: Synthetic & Systems Biotechnology. Jun2023, Vol. 8 Issue 2, p206-212. 7p.

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Skocz do pozycji: 20.

Tytuł:: Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7.
Autorzy:: Nakamura A; Department of Science of Technology Innovation, Nagaoka University of Technology, 1603-1 Kamitomioka, Nagaoka, Niigata, 940-2188, Japan.
Suzuki Y; National Institute of Technology (KOSEN), Nagaoka College, 888 Nishikatakai, Nagaoka, Niigata, 940-8532, Japan.
Sakamoto Y; School of Pharmacy, Iwate Medical University, 1-1-1 Idaidori, Yahaba, Iwate, 028-3694, Japan.
Roppongi S; School of Medicine, Iwate Medical University, 1-1-1 Idaidori, Yahaba, Iwate, 028-3694, Japan.
Kushibiki C; School of Pharmacy, Iwate Medical University, 1-1-1 Idaidori, Yahaba, Iwate, 028-3694, Japan.
Yonezawa N; School of Pharmacy, Iwate Medical University, 1-1-1 Idaidori, Yahaba, Iwate, 028-3694, Japan.; School of Pharmacy, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.
Takahashi M; School of Pharmacy, Iwate Medical University, 1-1-1 Idaidori, Yahaba, Iwate, 028-3694, Japan.
Shida Y; Department of Bioengineering, Nagaoka University of Technology, 1603-1 Kamitomioka, Nagaoka, Niigata, 940-2188, Japan.
Gouda H; School of Pharmacy, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.
Nonaka T; School of Pharmacy, Iwate Medical University, 1-1-1 Idaidori, Yahaba, Iwate, 028-3694, Japan.
Tanaka N; School of Pharmacy, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan. .; School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan. .
Ogasawara W; Department of Science of Technology Innovation, Nagaoka University of Technology, 1603-1 Kamitomioka, Nagaoka, Niigata, 940-2188, Japan. .; Department of Bioengineering, Nagaoka University of Technology, 1603-1 Kamitomioka, Nagaoka, Niigata, 940-2188, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Apr 12; Vol. 11 (1), pp. 7929. Date of Electronic Publication: 2021 Apr 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Asparagine/*chemistry
Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/*chemistry
Stenotrophomonas maltophilia/*enzymology
Amino Acid Sequence ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/antagonists & inhibitors ; Hydrophobic and Hydrophilic Interactions ; Kinetics ; Models, Molecular ; Mutagenesis, Site-Directed ; Substrate Specificity ; Thermodynamics

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