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Wyszukujesz frazę ""Peptide Fragments"" wg kryterium: Temat


Tytuł :
Detection and quantification of Mycobacterium tuberculosis antigen CFP10 in serum and urine for the rapid diagnosis of active tuberculosis disease.
Autorzy :
Seifert M; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA. .
Vargas E; Department of Nanoengineering, University California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Ruiz-Valdepeñas Montiel V; Department of Nanoengineering, University California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Wang J; Department of Nanoengineering, University California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Rodwell TC; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Catanzaro A; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
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Źródło :
Scientific reports [Sci Rep] 2021 Sep 28; Vol. 11 (1), pp. 19193. Date of Electronic Publication: 2021 Sep 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Peptide Fragments*/blood
Peptide Fragments*/isolation & purification
Peptide Fragments*/urine
Diagnostic Tests, Routine/*methods
Tuberculosis/*diagnosis
Antigens, Bacterial/blood ; Antigens, Bacterial/isolation & purification ; Antigens, Bacterial/urine ; Mycobacterium tuberculosis/immunology ; Sensitivity and Specificity ; Tuberculosis, Pulmonary/diagnosis
Czasopismo naukowe
Tytuł :
An Albumin-Binding Domain Peptide Confers Enhanced Immunoprotection Against Viral Myocarditis by CVB3 VP1 Vaccine.
Autorzy :
Gao Y; Jiangsu Provincial Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Science, Soochow University, Suzhou, China.
Yue Y; Jiangsu Provincial Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Science, Soochow University, Suzhou, China.
Xiong S; Jiangsu Provincial Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Science, Soochow University, Suzhou, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Sep 22; Vol. 12, pp. 666594. Date of Electronic Publication: 2021 Sep 22 (Print Publication: 2021).
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunogenicity, Vaccine*
Bacterial Proteins/*administration & dosage
Capsid Proteins/*administration & dosage
Coxsackievirus Infections/*prevention & control
Enterovirus B, Human/*immunology
Myocarditis/*prevention & control
Peptide Fragments/*administration & dosage
Serum Albumin/*metabolism
Viral Vaccines/*administration & dosage
Animals ; Bacterial Proteins/immunology ; Bacterial Proteins/metabolism ; Capsid Proteins/immunology ; Capsid Proteins/metabolism ; Coxsackievirus Infections/immunology ; Coxsackievirus Infections/metabolism ; Coxsackievirus Infections/virology ; Disease Models, Animal ; HeLa Cells ; Humans ; Immunization ; Male ; Mice, Inbred BALB C ; Myocarditis/immunology ; Myocarditis/metabolism ; Myocarditis/virology ; Peptide Fragments/immunology ; Peptide Fragments/metabolism ; Protein Binding ; Protein Interaction Domains and Motifs ; Vaccines, Synthetic/administration & dosage ; Vaccines, Synthetic/immunology ; Vaccines, Synthetic/metabolism ; Viral Vaccines/immunology ; Viral Vaccines/metabolism
Czasopismo naukowe
Tytuł :
Protective Role of a Donepezil-Huprine Hybrid against the β-Amyloid (1-42) Effect on Human Erythrocytes.
Autorzy :
Zambrano P; Facultad de Ciencias Químicas, Universidad de Concepción, Concepción 4030000, Chile.
Suwalsky M; Facultad de Medicina, Universidad Católica de la Santísima Concepción, Concepción 4030000, Chile.
Jemiola-Rzeminska M; Malopolska Centre of Biotechnology, Jagiellonian University, 30-387 Kraków, Poland.; Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 30-387 Kraków, Poland.
Gallardo-Nelson MJ; School of Medicine, University of Atacama, Copiapó 1530000, Chile.
Strzalka K; Malopolska Centre of Biotechnology, Jagiellonian University, 30-387 Kraków, Poland.; Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 30-387 Kraków, Poland.
Muñoz-Torrero D; Laboratory of Medicinal Chemistry (CSIC Associated Unit), Faculty of Pharmacy and Food, Sciences, University of Barcelona (UB), E-08028 Barcelona, Spain.; Institute of Biomedicine (IBUB), University of Barcelona (UB), E-08028 Barcelona, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 03; Vol. 22 (17). Date of Electronic Publication: 2021 Sep 03.
Typ publikacji :
Journal Article
MeSH Terms :
Amyloid beta-Peptides*/chemistry
Amyloid beta-Peptides*/toxicity
Erythrocyte Membrane*/chemistry
Erythrocyte Membrane*/metabolism
Erythrocyte Membrane*/ultrastructure
Heterocyclic Compounds, 4 or More Rings*/chemistry
Heterocyclic Compounds, 4 or More Rings*/pharmacology
Models, Molecular*
Peptide Fragments*/chemistry
Peptide Fragments*/toxicity
Alzheimer Disease/drug therapy ; Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Humans
Czasopismo naukowe
Tytuł :
Pegylated LyeTx I-b peptide is effective against carbapenem-resistant Acinetobacter baumannii in an in vivo model of pneumonia and shows reduced toxicity.
Autorzy :
César Moreira Brito J; Programa de Inovação Tecnológica e Biofarmacêutica, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Fundação Ezequiel Dias, Belo Horizonte, Minas Gerais, Brazil. Electronic address: .
Gustavo Lima W; Laboratório de Radioisótopos, Departamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Campus Pampulha, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Magalhães Resende J; Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Cristina Sampaio de Assis D; Escola de Veterinária, Departamento de Inspeção Sanitária, Campus Pampulha, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil.
Boff D; Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Nascimento Cardoso V; Laboratório de Radioisótopos, Departamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Campus Pampulha, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Almeida Amaral F; Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Maria Souza-Fagundes E; Programa de Inovação Tecnológica e Biofarmacêutica, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.
Odília Antunes Fernandes S; Laboratório de Radioisótopos, Departamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Campus Pampulha, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Elena de Lima M; Programa de Inovação Tecnológica e Biofarmacêutica, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Faculdade Santa Casa de Belo Horizonte: Programa de Pós-Graduação em Medicina-Biomedicina, Belo Horizonte, Minas Gerais, Brazil. Electronic address: .
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Źródło :
International journal of pharmaceutics [Int J Pharm] 2021 Nov 20; Vol. 609, pp. 121156. Date of Electronic Publication: 2021 Oct 06.
Typ publikacji :
Journal Article
MeSH Terms :
Acinetobacter baumannii*
Antimicrobial Cationic Peptides*
Peptide Fragments*/pharmacology
Pneumonia*
Animals ; Carbapenems ; Drug Resistance, Bacterial ; Drug Synergism ; Gentamicins/pharmacology ; HEK293 Cells ; Humans ; Mice ; Microbial Sensitivity Tests ; Peptides ; Polyethylene Glycols ; Receptors for Activated C Kinase
Czasopismo naukowe
Tytuł :
A Comprehensive Insight into the Mechanisms of Dopamine in Disrupting Aβ Protofibrils and Inhibiting Aβ Aggregation.
Autorzy :
Chen Y; Department of Physics, State Key Laboratory of Surface Physics, and Key Laboratory for Computational Physical Sciences (Ministry of Education), Fudan University, Shanghai 200438, People's Republic of China.
Li X; MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi'an Jiaotong University, Xi'an 710049, People's Republic of China.
Zhan C; Department of Physics, State Key Laboratory of Surface Physics, and Key Laboratory for Computational Physical Sciences (Ministry of Education), Fudan University, Shanghai 200438, People's Republic of China.
Lao Z; Department of Physics, State Key Laboratory of Surface Physics, and Key Laboratory for Computational Physical Sciences (Ministry of Education), Fudan University, Shanghai 200438, People's Republic of China.
Li F; Department of Physics, State Key Laboratory of Surface Physics, and Key Laboratory for Computational Physical Sciences (Ministry of Education), Fudan University, Shanghai 200438, People's Republic of China.
Dong X; Department of Physics, State Key Laboratory of Surface Physics, and Key Laboratory for Computational Physical Sciences (Ministry of Education), Fudan University, Shanghai 200438, People's Republic of China.
Wei G; Department of Physics, State Key Laboratory of Surface Physics, and Key Laboratory for Computational Physical Sciences (Ministry of Education), Fudan University, Shanghai 200438, People's Republic of China.
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Źródło :
ACS chemical neuroscience [ACS Chem Neurosci] 2021 Nov 03; Vol. 12 (21), pp. 4007-4019. Date of Electronic Publication: 2021 Sep 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dopamine*
Peptide Fragments*
Amyloid beta-Peptides ; Molecular Dynamics Simulation ; Protein Conformation, beta-Strand
Czasopismo naukowe
Tytuł :
Small p53 derived peptide suitable for robust nanobodies dimerization.
Autorzy :
Dietsch F; Université de Strasbourg, UMR7242 Biotechnologie et Signalisation Cellulaire, Ecole Supérieure de Biotechnologie Strasbourg, F-67412 Illkirch, France.
Nominé Y; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, F-67412 Illkirch, France.
Stoessel A; Université de Strasbourg, UMR7242 Biotechnologie et Signalisation Cellulaire, Ecole Supérieure de Biotechnologie Strasbourg, F-67412 Illkirch, France.
Kostmann C; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, F-67412 Illkirch, France.
Bonhoure A; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, F-67412 Illkirch, France.
Chatton B; Université de Strasbourg, UMR7242 Biotechnologie et Signalisation Cellulaire, Ecole Supérieure de Biotechnologie Strasbourg, F-67412 Illkirch, France.
Donzeau M; Université de Strasbourg, UMR7242 Biotechnologie et Signalisation Cellulaire, Ecole Supérieure de Biotechnologie Strasbourg, F-67412 Illkirch, France. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2021 Nov; Vol. 498, pp. 113144. Date of Electronic Publication: 2021 Sep 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epitopes*
Green Fluorescent Proteins/*immunology
Peptide Fragments/*immunology
Single-Domain Antibodies/*immunology
Tumor Suppressor Protein p53/*immunology
Animals ; Antibody Affinity ; Antibody Specificity ; Green Fluorescent Proteins/genetics ; HeLa Cells ; Humans ; Mutation ; Peptide Fragments/genetics ; Protein Multimerization ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł :
Influence of in vitro neuronal membranes on the anti-amyloidogenic activity of gallic acid: Implication for the therapy of Alzheimer's disease.
Autorzy :
Andrade S; LEPABE - Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465, Porto, Portugal.
Loureiro JA; LEPABE - Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465, Porto, Portugal. Electronic address: .
Pereira MDC; LEPABE - Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465, Porto, Portugal. Electronic address: .
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2021 Oct 30; Vol. 711, pp. 109022. Date of Electronic Publication: 2021 Aug 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amyloid beta-Peptides/*metabolism
Gallic Acid/*chemistry
Liposomes/*chemistry
Peptide Fragments/*metabolism
Protein Multimerization/*drug effects
Alzheimer Disease/drug therapy ; Amyloid beta-Peptides/chemistry ; Humans ; Kinetics ; Peptide Fragments/chemistry ; Protein Conformation, alpha-Helical/drug effects ; Protein Conformation, beta-Strand/drug effects
Czasopismo naukowe
Tytuł :
EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.
Autorzy :
Chang K; Department of Pathology, School of Basic Medical Sciences, Fudan University, 131 Dongan Road, Shanghai, 200032, China.
Xue R; Department of Pathology, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.
Zhao M; Department of Pathology, School of Basic Medical Sciences, Fudan University, 131 Dongan Road, Shanghai, 200032, China.
Zhao Y; Department of Pathology, School of Basic Medical Sciences, Fudan University, 131 Dongan Road, Shanghai, 200032, China.
Yu W; Department of Pathology, School of Basic Medical Sciences, Fudan University, 131 Dongan Road, Shanghai, 200032, China.
Zhao Z; Department of Pathology, School of Basic Medical Sciences, Fudan University, 131 Dongan Road, Shanghai, 200032, China.
Liu X; Department of Pathology, School of Basic Medical Sciences, Fudan University, 131 Dongan Road, Shanghai, 200032, China; Shanghai Key Laboratory of Kidney Disease and Blood Purification, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2021 Oct 15; Vol. 407 (2), pp. 112825. Date of Electronic Publication: 2021 Sep 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Dedifferentiation*
Cyclic AMP/*metabolism
Cyclic AMP-Dependent Protein Kinases/*metabolism
E1A-Associated p300 Protein/*metabolism
Glomerulosclerosis, Focal Segmental/*pathology
Peptide Fragments/*metabolism
Podocytes/*pathology
Receptor, Notch3/*metabolism
Sialoglycoproteins/*metabolism
Adult ; Animals ; Apoptosis ; Biomarkers/metabolism ; Cell Proliferation ; Cells, Cultured ; E1A-Associated p300 Protein/genetics ; Female ; Gene Expression Regulation ; Glomerulosclerosis, Focal Segmental/genetics ; Glomerulosclerosis, Focal Segmental/metabolism ; Humans ; Male ; Mice ; Peptide Fragments/genetics ; Podocytes/metabolism ; Prognosis ; Rats ; Rats, Sprague-Dawley ; Receptor, Notch3/genetics ; Sialoglycoproteins/genetics
Czasopismo naukowe
Tytuł :
Enhancing Antigen Presentation and Inducing Antigen-Specific Immune Tolerance with Amphiphilic Peptides.
Autorzy :
Li M; Department of Chemical Engineering and Materials Science, Wayne State University, Detroit, MI.
Itoh A; Division of Rheumatology, Allergy, and Clinical Immunology, University of California, Davis, Davis, CA.
Xi J; Department of Chemical Engineering and Materials Science, Wayne State University, Detroit, MI.
Yu C; Department of Chemical Engineering and Materials Science, Wayne State University, Detroit, MI.
Wu Y; Division of Rheumatology, Allergy, and Clinical Immunology, University of California, Davis, Davis, CA.
Ridgway WM; Division of Rheumatology, Allergy, and Clinical Immunology, University of California, Davis, Davis, CA.
Liu H; Department of Chemical Engineering and Materials Science, Wayne State University, Detroit, MI; .; Department of Oncology, Wayne State University, Detroit, MI; and.; Tumor Biology and Microenvironment Program, Barbara Ann Karmanos Cancer Institute, Detroit, MI.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Oct 15; Vol. 207 (8), pp. 2051-2059. Date of Electronic Publication: 2021 Sep 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
CD4-Positive T-Lymphocytes/*immunology
Diabetes Mellitus, Type 1/*immunology
Epitopes, T-Lymphocyte/*metabolism
Insulin/*metabolism
Peptide Fragments/*metabolism
Surface-Active Agents/*metabolism
Albumins ; Animals ; Antigen Presentation ; Female ; Humans ; Immune Tolerance ; Immunization ; Immunomodulation ; Insulin/immunology ; Lymphocyte Activation ; Mice ; Mice, Inbred C57BL ; Mice, Inbred NOD ; Peptide Fragments/immunology
Czasopismo naukowe
Tytuł :
Residual Helicity at the Active Site of the Histidine Phosphocarrier, HPr, Modulates Binding Affinity to Its Natural Partners.
Autorzy :
Neira JL; IDIBE, Universidad Miguel Hernández, 03202 Elche, Spain.; Joint Units IQFR-CSIC-BIFI, and GBsC-CSIC-BIFI, Instituto de Biocomputación y Física de Sistemas Complejos (BIFI), Universidad de Zaragoza, 50018 Zaragoza, Spain.
Ortega-Alarcón D; Joint Units IQFR-CSIC-BIFI, and GBsC-CSIC-BIFI, Instituto de Biocomputación y Física de Sistemas Complejos (BIFI), Universidad de Zaragoza, 50018 Zaragoza, Spain.; Departamento de Bioquímica y Biología Molecular y Celular, Universidad de Zaragoza, 50009 Zaragoza, Spain.
Rizzuti B; Joint Units IQFR-CSIC-BIFI, and GBsC-CSIC-BIFI, Instituto de Biocomputación y Física de Sistemas Complejos (BIFI), Universidad de Zaragoza, 50018 Zaragoza, Spain.; CNR-NANOTEC, SS Rende (CS), Department of Physics, University of Calabria, Via P. Bucci, Cubo 31 C, 87036 Rende, Italy.
Palomino-Schätzlein M; Centro de Investigación Príncipe Felipe, Calle Eduardo Primo Yufera 3, 46022 Valencia, Spain.
Velázquez-Campoy A; Joint Units IQFR-CSIC-BIFI, and GBsC-CSIC-BIFI, Instituto de Biocomputación y Física de Sistemas Complejos (BIFI), Universidad de Zaragoza, 50018 Zaragoza, Spain.; Departamento de Bioquímica y Biología Molecular y Celular, Universidad de Zaragoza, 50009 Zaragoza, Spain.; Instituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.; Centro de Investigación Biomédica en Red en el Área Temática de Enfermedades Hepáticas y Digestivas (CIBERehd), 28029 Madrid, Spain.; Fundacion ARAID, Government of Aragon, 50009 Zaragoza, Spain.
Falcó A; IDIBE, Universidad Miguel Hernández, 03202 Elche, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 06; Vol. 22 (19). Date of Electronic Publication: 2021 Oct 06.
Typ publikacji :
Journal Article
MeSH Terms :
Mutation*
Anti-Bacterial Agents/*pharmacology
Bacterial Proteins/*metabolism
Histidine/*metabolism
Peptide Fragments/*pharmacology
Phosphoenolpyruvate Sugar Phosphotransferase System/*metabolism
Staphylococcus aureus/*drug effects
Anti-Bacterial Agents/chemistry ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Binding Sites ; Catalytic Domain ; Histidine/chemistry ; Peptide Fragments/chemistry ; Phosphoenolpyruvate Sugar Phosphotransferase System/chemistry ; Phosphoenolpyruvate Sugar Phosphotransferase System/genetics ; Staphylococcus aureus/metabolism
Czasopismo naukowe
Tytuł :
Urantide prevents CCl4‑induced acute liver injury in rats by regulating the MAPK signalling pathway.
Autorzy :
Li Y; Department of Pathophysiology, Chengde Medical University, Chengde, Hebei 067000, P.R. China.
Guo Z; Second Department of Trauma, Third Hospital of Shijiazhuang City, Shijiazhuang, Hebei 050000, P.R. China.
Cui H; Department of Pathophysiology, Chengde Medical University, Chengde, Hebei 067000, P.R. China.
Wang T; Department of Pathophysiology, Chengde Medical University, Chengde, Hebei 067000, P.R. China.
Xu Y; Department of Pathophysiology, Chengde Medical University, Chengde, Hebei 067000, P.R. China.
Zhao J; Department of Pathophysiology, Chengde Medical University, Chengde, Hebei 067000, P.R. China.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2021 Oct; Vol. 24 (4). Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Chemical and Drug Induced Liver Injury/*metabolism
Chemical and Drug Induced Liver Injury/*prevention & control
MAP Kinase Signaling System/*drug effects
Peptide Fragments/*pharmacology
Urotensins/*pharmacology
Actins/genetics ; Actins/metabolism ; Animals ; Carbon Tetrachloride/toxicity ; Disease Models, Animal ; Extracellular Signal-Regulated MAP Kinases/genetics ; Extracellular Signal-Regulated MAP Kinases/metabolism ; MAP Kinase Kinase 4/genetics ; MAP Kinase Kinase 4/metabolism ; Male ; Osteopontin/genetics ; Osteopontin/metabolism ; Peptide Fragments/therapeutic use ; Rats, Sprague-Dawley ; Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/metabolism ; Urotensins/therapeutic use ; p38 Mitogen-Activated Protein Kinases/genetics ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
Tytuł :
In vivo imaging of synaptic density with [ C]UCB-J PET in two mouse models of neurodegenerative disease.
Autorzy :
Xiong M; Molecular Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala SE-751 85, Sweden.
Roshanbin S; Molecular Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala SE-751 85, Sweden.
Rokka J; Molecular Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala SE-751 85, Sweden.
Schlein E; Molecular Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala SE-751 85, Sweden.
Ingelsson M; Molecular Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala SE-751 85, Sweden.
Sehlin D; Molecular Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala SE-751 85, Sweden.
Eriksson J; Department of Medicinal Chemistry, Uppsala University, Uppsala SE-751 23, Sweden; PET Centre, Uppsala University Hospital, Uppsala SE-751 85, Sweden.
Syvänen S; Molecular Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala SE-751 85, Sweden. Electronic address: .
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Źródło :
NeuroImage [Neuroimage] 2021 Oct 01; Vol. 239, pp. 118302. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Amyloid beta-Peptides/*analysis
Brain/*diagnostic imaging
Carbon Radioisotopes/*pharmacokinetics
Membrane Glycoproteins/*analysis
Nerve Tissue Proteins/*analysis
Peptide Fragments/*analysis
Positron-Emission Tomography/*methods
Pyridines/*pharmacokinetics
Pyrrolidinones/*pharmacokinetics
Radiopharmaceuticals/*pharmacokinetics
Synaptic Vesicles/*ultrastructure
Synucleinopathies/*diagnostic imaging
Aging ; Alzheimer Disease ; Amyloid beta-Peptides/genetics ; Animals ; Area Under Curve ; Brain/ultrastructure ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Organ Specificity ; Parkinson Disease ; Peptide Fragments/genetics
Czasopismo naukowe
Tytuł :
Angiotensin-(1-7)/Mas receptor modulates anti-inflammatory effects of exercise training in a model of chronic allergic lung inflammation.
Autorzy :
Gregório JF; Department of Physiology and Biophysics, National Institute of Science and Technology in Nanobiopharmaceutics (INCT-Nanobiofar), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Magalhães GS; Department of Physiology and Biophysics, National Institute of Science and Technology in Nanobiopharmaceutics (INCT-Nanobiofar), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil; Post-Graduate Program in Healthy Sciences of Faculty of Medical Sciences of Minas Gerais, Belo Horizonte, MG, Brazil.
Rodrigues-Machado MG; Post-Graduate Program in Healthy Sciences of Faculty of Medical Sciences of Minas Gerais, Belo Horizonte, MG, Brazil.
Gonzaga KER; Department of Physiology and Biophysics, National Institute of Science and Technology in Nanobiopharmaceutics (INCT-Nanobiofar), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil; Post-Graduate Program in Healthy Sciences of Faculty of Medical Sciences of Minas Gerais, Belo Horizonte, MG, Brazil.
Motta-Santos D; Department of Physiology and Biophysics, National Institute of Science and Technology in Nanobiopharmaceutics (INCT-Nanobiofar), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil; Sports Department, School of Physical Education, Physiotherapy and Occupational Therapy, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Cassini-Vieira P; Department of Physiology and Biophysics, National Institute of Science and Technology in Nanobiopharmaceutics (INCT-Nanobiofar), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Barcelos LS; Department of Physiology and Biophysics, National Institute of Science and Technology in Nanobiopharmaceutics (INCT-Nanobiofar), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Vieira MAR; Department of Physiology and Biophysics, National Institute of Science and Technology in Nanobiopharmaceutics (INCT-Nanobiofar), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Santos RAS; Department of Physiology and Biophysics, National Institute of Science and Technology in Nanobiopharmaceutics (INCT-Nanobiofar), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Campagnole-Santos MJ; Department of Physiology and Biophysics, National Institute of Science and Technology in Nanobiopharmaceutics (INCT-Nanobiofar), Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Oct 01; Vol. 282, pp. 119792. Date of Electronic Publication: 2021 Jul 03.
Typ publikacji :
Journal Article
MeSH Terms :
Angiotensin I/*metabolism
Asthma/*therapy
Peptide Fragments/*metabolism
Pneumonia/*therapy
Angiotensin I/blood ; Animals ; Asthma/blood ; Asthma/metabolism ; Disease Models, Animal ; Exercise Therapy ; Male ; Mice, Inbred BALB C ; Peptide Fragments/blood ; Pneumonia/blood ; Pneumonia/metabolism
Czasopismo naukowe
Tytuł :
Perioperative supplemental oxygen and NT-proBNP concentrations after major abdominal surgery - A prospective randomized clinical trial.
Autorzy :
Reiterer C; Department of Anaesthesia, General Intensive Care Medicine and Pain Medicine, Medical University of Vienna, 1090 Vienna, Austria.
Kabon B; Department of Anaesthesia, General Intensive Care Medicine and Pain Medicine, Medical University of Vienna, 1090 Vienna, Austria. Electronic address: .
Taschner A; Department of Anaesthesia, General Intensive Care Medicine and Pain Medicine, Medical University of Vienna, 1090 Vienna, Austria.
Falkner von Sonnenburg M; Department of Anaesthesia, General Intensive Care Medicine and Pain Medicine, Medical University of Vienna, 1090 Vienna, Austria.
Graf A; Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, 1090 Vienna, Austria.
Adamowitsch N; Department of Anaesthesia, General Intensive Care Medicine and Pain Medicine, Medical University of Vienna, 1090 Vienna, Austria.
Starlinger P; Department of Surgery, Medical University of Vienna, 1090 Vienna, Austria.
Goshin J; Department of Anaesthesia, General Intensive Care Medicine and Pain Medicine, Medical University of Vienna, 1090 Vienna, Austria.
Fraunschiel M; IT Systems and Communications, Medical University of Vienna, 1090 Vienna, Austria.
Fleischmann E; Department of Anaesthesia, General Intensive Care Medicine and Pain Medicine, Medical University of Vienna, 1090 Vienna, Austria.
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Źródło :
Journal of clinical anesthesia [J Clin Anesth] 2021 Oct; Vol. 73, pp. 110379. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Natriuretic Peptide, Brain*
Peptide Fragments*
Biomarkers ; Humans ; Middle Aged ; Oxygen ; Prospective Studies ; Risk Assessment
Czasopismo naukowe
Tytuł :
Deconvoluting complex protein interaction networks through reductionist strategies in peptide biochemistry: Modern approaches and research questions.
Autorzy :
Lukinović V; Institute of Biochemistry, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario K1S 5B6, Canada.
Biggar KK; Institute of Biochemistry, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario K1S 5B6, Canada. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Oct-Dec; Vol. 256, pp. 110616. Date of Electronic Publication: 2021 May 15.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Processing, Post-Translational*
Peptide Fragments/*metabolism
Proteins/*metabolism
Proteome/*metabolism
Animals ; Humans ; Peptide Fragments/chemistry ; Protein Interaction Maps ; Proteins/chemistry
Czasopismo naukowe
Tytuł :
Synthesis and characterization of peptide conjugated human serum albumin nanoparticles for targeted cardiac uptake and drug delivery.
Autorzy :
Lomis N; Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Montreal, QC, Canada.; Division of Experimental Medicine, Montréal, QC, Canada.
Westfall S; Meakins Christie Laboratories, Department of Microbiology and Immunology, McGill University, Montréal, QC, Canada.
Shum-Tim D; Division of Cardiac Surgery and Surgical Research, Royal Victoria Hospital, Montréal, QC, Canada.
Prakash S; Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering, Montreal, QC, Canada.; Division of Experimental Medicine, Montréal, QC, Canada.
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Źródło :
PloS one [PLoS One] 2021 Sep 30; Vol. 16 (9), pp. e0254305. Date of Electronic Publication: 2021 Sep 30 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Delivery Systems*
Milrinone/*pharmacology
Myocytes, Cardiac/*drug effects
Nanoparticles/*administration & dosage
Peptide Fragments/*pharmacology
Serum Albumin, Human/*chemistry
Animals ; Biological Transport ; Cardiotonic Agents/chemistry ; Cardiotonic Agents/pharmacology ; Cell Survival ; Drug Carriers ; Humans ; Milrinone/chemistry ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/metabolism ; Nanoparticles/chemistry ; Peptide Fragments/chemistry ; Rats
Czasopismo naukowe
Tytuł :
Ang-(1-7) protects skeletal muscle function in aged mice.
Autorzy :
Li Y; The Center of Gerontology and Geriatrics, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Sichuan, China.
Song J; The Center of Gerontology and Geriatrics, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Sichuan, China.
Jiang Y; The Center of Gerontology and Geriatrics, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Sichuan, China.
Yang X; The Center of Gerontology and Geriatrics, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Sichuan, China.
Cao L; The Center of Gerontology and Geriatrics, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Sichuan, China.
Xiao C; The Center of Gerontology and Geriatrics, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Sichuan, China.
Li S; Chengdu Koamy Biotechnology Co, Ltd, Chengdu, Sichuan, China.
Dong B; The Center of Gerontology and Geriatrics, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Sichuan, China.
Huang X; The Center of Gerontology and Geriatrics, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Sichuan, China. .; The Center of Gerontology and Geriatrics, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, 37 Guoxuexiang, Sichuan providence, 610041, Chengdu, P.R. China. .
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Źródło :
BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2021 Sep 21; Vol. 22 (1), pp. 809. Date of Electronic Publication: 2021 Sep 21.
Typ publikacji :
Journal Article
MeSH Terms :
Angiotensin I*
Peptide Fragments*
Animals ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle, Skeletal
Czasopismo naukowe
Tytuł :
NMR reveals the interplay between SilE and SilB model peptides in the context of silver resistance.
Autorzy :
Babel L; University of Fribourg, Department of Chemistry, chemin du musée 9, Fribourg 1700, Switzerland.
Nguyen MH
Mittelheisser C
Martin M
Fromm KM
Walker O
Hologne M
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2021 Sep 11; Vol. 57 (70), pp. 8726-8729. Date of Electronic Publication: 2021 Aug 16.
Typ publikacji :
Journal Article
MeSH Terms :
Bacterial Proteins/*metabolism
Carrier Proteins/*metabolism
Peptide Fragments/*metabolism
Silver/*metabolism
Amino Acid Sequence ; Bacterial Proteins/chemistry ; Binding Sites ; Carrier Proteins/chemistry ; Drug Resistance, Bacterial ; Nuclear Magnetic Resonance, Biomolecular ; Peptide Fragments/chemistry ; Protein Binding ; Salmonella typhimurium/chemistry
Czasopismo naukowe
Tytuł :
Unveiling the Metabolic Effects of Glycomacropeptide.
Autorzy :
Pena MJ; Departamento de Biomedicina, Unidade de Bioquímica, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.
Costa R; Departamento de Biomedicina, Unidade de Bioquímica, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.
Rodrigues I; Departamento de Biomedicina, Unidade de Bioquímica, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.
Martins S; Department of Clinical Pathology, São João Hospital Centre, 4200-319 Porto, Portugal.; Instituto de Saúde Pública, Universidade do Porto, 4050-091 Porto, Portugal.
Guimarães JT; Departamento de Biomedicina, Unidade de Bioquímica, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.; Department of Clinical Pathology, São João Hospital Centre, 4200-319 Porto, Portugal.; Instituto de Saúde Pública, Universidade do Porto, 4050-091 Porto, Portugal.
Faria A; Nutrition & Metabolism, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal.; CINTESIS-Centre for Health Technology and Services Research, 4200-450 Porto, Portugal.; CHRC-Comprehensive Health Research Centre, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal.
Calhau C; Nutrition & Metabolism, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal.; CINTESIS-Centre for Health Technology and Services Research, 4200-450 Porto, Portugal.; Unidade Universitária Lifestyle Medicine da José de Mello Saúde by NOVA Medical School, 1169-056 Lisboa, Portugal.
Rocha JC; Nutrition & Metabolism, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal.; CINTESIS-Centre for Health Technology and Services Research, 4200-450 Porto, Portugal.; Reference Centre of Inherited Metabolic Diseases, Centro Hospitalar Universitário de Lisboa Central, 1169-045 Lisboa, Portugal.
Borges N; CINTESIS-Centre for Health Technology and Services Research, 4200-450 Porto, Portugal.; Faculdade de Ciências da Nutrição e Alimentação, Universidade do Porto, 4150-180 Porto, Portugal.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 08; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Journal Article
MeSH Terms :
Diet Therapy*
Dietary Supplements*
Caseins/*metabolism
Peptide Fragments/*metabolism
Animals ; Biomarkers ; Body Weight ; Caseins/administration & dosage ; Eating ; Glucose/metabolism ; Humans ; Immunohistochemistry ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/pathology ; Peptide Fragments/administration & dosage ; Rats
Czasopismo naukowe
Tytuł :
Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope.
Autorzy :
Schilz J; Lehrstuhl für Biologische Chemie, Technische Universität München, Emil-Erlenmeyer-Forum 5, 85354 Freising, Germany.
Binder U; XL-protein GmbH, Lise-Meitner-Strasse 30, 85354 Freising, Germany.
Friedrich L; XL-protein GmbH, Lise-Meitner-Strasse 30, 85354 Freising, Germany.
Gebauer M; XL-protein GmbH, Lise-Meitner-Strasse 30, 85354 Freising, Germany.
Lutz C; Lehrstuhl für Biologische Chemie, Technische Universität München, Emil-Erlenmeyer-Forum 5, 85354 Freising, Germany.
Schlapschy M; Lehrstuhl für Biologische Chemie, Technische Universität München, Emil-Erlenmeyer-Forum 5, 85354 Freising, Germany.
Schiefner A; Lehrstuhl für Biologische Chemie, Technische Universität München, Emil-Erlenmeyer-Forum 5, 85354 Freising, Germany.
Skerra A; Lehrstuhl für Biologische Chemie, Technische Universität München, Emil-Erlenmeyer-Forum 5, 85354 Freising, Germany; XL-protein GmbH, Lise-Meitner-Strasse 30, 85354 Freising, Germany. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Sep 03; Vol. 433 (18), pp. 167113. Date of Electronic Publication: 2021 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Monoclonal/*immunology
Dipeptides/*immunology
Epitopes/*immunology
Intrinsically Disordered Proteins/*immunology
Peptide Fragments/*immunology
Amino Acid Sequence ; Animals ; Antibodies, Monoclonal/chemistry ; Dipeptides/chemistry ; Epitopes/chemistry ; Intrinsically Disordered Proteins/chemistry ; Mice ; Mice, Inbred BALB C ; Peptide Fragments/chemistry ; Protein Structure, Secondary ; Sequence Homology
Czasopismo naukowe

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