Temat: "Peptide Fragments" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The effects of carvacrol and p-cymene on Aβ 1-42 -induced long-term potentiation deficit in male rats.
Autorzy:: Kazemi S; Department of Neuroscience, School of Science and Advanced Technologies in Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Safari S; Department of Neuroscience, School of Science and Advanced Technologies in Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.; Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran.
Komaki S; Department of Physiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Karimi SA; Department of Neuroscience, School of Science and Advanced Technologies in Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.; Department of Physiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Golipoor Z; Cellular and Molecular Research Center, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Komaki A; Department of Neuroscience, School of Science and Advanced Technologies in Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.; Department of Physiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.; Pokaż więcej
Źródło:: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Mar; Vol. 30 (3), pp. e14459. Date of Electronic Publication: 2023 Sep 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Long-Term Potentiation*/physiology
Alzheimer Disease*/metabolism
Cymenes*
Peptide Fragments*
Rats ; Male ; Animals ; Rats, Wistar ; Amyloid beta-Peptides/toxicity ; Amyloid beta-Peptides/metabolism ; Hippocampus/metabolism ; Dentate Gyrus/metabolism

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Skocz do pozycji: 2.

Tytuł:: A data-driven approach to complement the A/T/(N) classification system using CSF biomarkers.
Autorzy:: Hernández-Lorenzo L; Department of Neurology, San Carlos Research Institute (IdSSC), Hospital Clínico San Carlos, Madrid, Spain.; Department of Computer Architecture and Automation, Computer Science Faculty, Complutense University of Madrid, Madrid, Spain.
Gil-Moreno MJ; Department of Neurology, San Carlos Research Institute (IdSSC), Hospital Clínico San Carlos, Madrid, Spain.
Ortega-Madueño I; Department of Clinical Analysis, Institute of Laboratory Medicine, IdSSC, Hospital Clínico San Carlos, Madrid, Spain.
Cárdenas MC; Department of Clinical Analysis, Institute of Laboratory Medicine, IdSSC, Hospital Clínico San Carlos, Madrid, Spain.
Diez-Cirarda M; Department of Neurology, San Carlos Research Institute (IdSSC), Hospital Clínico San Carlos, Madrid, Spain.
Delgado-Álvarez A; Department of Neurology, San Carlos Research Institute (IdSSC), Hospital Clínico San Carlos, Madrid, Spain.
Palacios-Sarmiento M; Department of Neurology, San Carlos Research Institute (IdSSC), Hospital Clínico San Carlos, Madrid, Spain.
Matias-Guiu J; Department of Neurology, San Carlos Research Institute (IdSSC), Hospital Clínico San Carlos, Madrid, Spain.
Corrochano S; Department of Neurology, San Carlos Research Institute (IdSSC), Hospital Clínico San Carlos, Madrid, Spain.
Ayala JL; Department of Computer Architecture and Automation, Computer Science Faculty, Complutense University of Madrid, Madrid, Spain.
Matias-Guiu JA; Department of Neurology, San Carlos Research Institute (IdSSC), Hospital Clínico San Carlos, Madrid, Spain.; Pokaż więcej
Corporate Authors:: Alzheimer's Disease Neuroimaging Initiative
Źródło:: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Feb; Vol. 30 (2), pp. e14382. Date of Electronic Publication: 2023 Jul 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Alzheimer Disease*/diagnostic imaging
Cognitive Dysfunction*/diagnostic imaging
Humans ; Amyloid beta-Peptides ; tau Proteins ; Biomarkers ; Peptide Fragments ; Disease Progression

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Skocz do pozycji: 3.

Tytuł:: A novel peptide derived from vascular endothelial growth factor prevents amyloid beta aggregation and toxicity.
Autorzy:: Bouvet P; MeLiS, Institut NeuroMyoGène (INMG), Synaptopathies and Autoantibodies, Institut National de la Santé et de la Recherche Médicale (INSERM), U1314, Centre National de la Recherche Scientifique (CNRS), UMR5284, Lyon, France.; Univ Lyon, Université Claude Bernard Lyon 1, Lyon, France.
de Gea P; MeLiS, Institut NeuroMyoGène (INMG), Synaptopathies and Autoantibodies, Institut National de la Santé et de la Recherche Médicale (INSERM), U1314, Centre National de la Recherche Scientifique (CNRS), UMR5284, Lyon, France.; Univ Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Aimard M; MeLiS, Institut NeuroMyoGène (INMG), Synaptopathies and Autoantibodies, Institut National de la Santé et de la Recherche Médicale (INSERM), U1314, Centre National de la Recherche Scientifique (CNRS), UMR5284, Lyon, France.; Univ Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Chounlamountri N; MeLiS, Institut NeuroMyoGène (INMG), Synaptopathies and Autoantibodies, Institut National de la Santé et de la Recherche Médicale (INSERM), U1314, Centre National de la Recherche Scientifique (CNRS), UMR5284, Lyon, France.; Univ Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Honnorat J; MeLiS, Institut NeuroMyoGène (INMG), Synaptopathies and Autoantibodies, Institut National de la Santé et de la Recherche Médicale (INSERM), U1314, Centre National de la Recherche Scientifique (CNRS), UMR5284, Lyon, France.; Univ Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Delcros JG; Univ Lyon, Université Claude Bernard Lyon 1, Lyon, France.; Centre de Recherche en Cancérologie de Lyon, Apoptosis, Cancer and Development, Institut PLAsCAN, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Lyon, France.; Centre de Recherche en Cancérologie de Lyon, Small Molecules for Biological Targets, INSERM U1052 - CNRS UMR5286, ISPB Rockefeller, Lyon, France.
Salin PA; Univ Lyon, Université Claude Bernard Lyon 1, Lyon, France.; Centre de Recherche en Neurosciences de Lyon, Forgetting Processes and Cortical Dynamics, INSERM U1028, CNRS UMR5292, Bron, France.
Meissirel C; MeLiS, Institut NeuroMyoGène (INMG), Synaptopathies and Autoantibodies, Institut National de la Santé et de la Recherche Médicale (INSERM), U1314, Centre National de la Recherche Scientifique (CNRS), UMR5284, Lyon, France.; Univ Lyon, Université Claude Bernard Lyon 1, Lyon, France.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Sep; Vol. 22 (9), pp. e13907. Date of Electronic Publication: 2023 Jul 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Amyloid beta-Peptides*/toxicity
Amyloid beta-Peptides*/metabolism
Alzheimer Disease*/metabolism
Mice ; Animals ; Vascular Endothelial Growth Factor A/pharmacology ; Vascular Endothelial Growth Factor A/metabolism ; Memory/physiology ; Learning ; Synapses/metabolism ; Peptide Fragments/pharmacology ; Peptide Fragments/metabolism

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Skocz do pozycji: 4.

Tytuł:: Advances and applications of fluids biomarkers in diagnosis and therapeutic targets of Alzheimer's disease.
Autorzy:: Xu Y; Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; School of Pharmacy, Capital Medical University, Beijing, China.
Jiang H; Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhu B; Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Cao M; Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Feng T; Center for Movement Disorders, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Sun Z; Department of Pharmacy, The Sixth Medical Center of PLA General Hospital, Beijing, China.
Du G; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Zhao Z; Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; School of Pharmacy, Capital Medical University, Beijing, China.; Pokaż więcej
Źródło:: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2023 Aug; Vol. 29 (8), pp. 2060-2073. Date of Electronic Publication: 2023 May 05.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Alzheimer Disease*/diagnosis
Alzheimer Disease*/drug therapy
Neurodegenerative Diseases*
Humans ; Amyloid Precursor Protein Secretases ; Aspartic Acid Endopeptidases ; tau Proteins/cerebrospinal fluid ; Amyloid beta-Peptides/cerebrospinal fluid ; Biomarkers/cerebrospinal fluid ; Peptide Fragments/cerebrospinal fluid

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Skocz do pozycji: 5.

Tytuł:: The efficacy and safety of ocriplasmin for patients with vitreous macular traction.
Autorzy:: Zhang WF; Department of Ophthalmology, Peking Union Medical, College Hospital, Chinese Academy of Medical Sciences, Beijing, China.; Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Zhao XY; Department of Ophthalmology, Peking Union Medical, College Hospital, Chinese Academy of Medical Sciences, Beijing, China.; Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Meng LH; Department of Ophthalmology, Peking Union Medical, College Hospital, Chinese Academy of Medical Sciences, Beijing, China.; Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Wang DY; Department of Ophthalmology, Peking Union Medical, College Hospital, Chinese Academy of Medical Sciences, Beijing, China.; Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Feng S; Department of Ophthalmology, Peking Union Medical, College Hospital, Chinese Academy of Medical Sciences, Beijing, China.; Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Chen YX; Department of Ophthalmology, Peking Union Medical, College Hospital, Chinese Academy of Medical Sciences, Beijing, China.; Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.; Pokaż więcej
Źródło:: Acta ophthalmologica [Acta Ophthalmol] 2022 Feb; Vol. 100 (1), pp. e304-e313. Date of Electronic Publication: 2021 May 21.
Typ publikacji:: Journal Article; Meta-Analysis
MeSH Terms:: Epiretinal Membrane/*drug therapy
Fibrinolysin/*administration & dosage
Fibrinolytic Agents/*administration & dosage
Peptide Fragments/*administration & dosage
Retinal Perforations/*drug therapy
Vitreous Detachment/*drug therapy
Aged ; Epiretinal Membrane/physiopathology ; Fibrinolysin/adverse effects ; Fibrinolytic Agents/adverse effects ; Humans ; Intravitreal Injections ; Middle Aged ; Peptide Fragments/adverse effects ; Retinal Perforations/physiopathology ; Tissue Adhesions ; Treatment Outcome ; Vitreous Detachment/physiopathology

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Skocz do pozycji: 6.

Tytuł:: The renal excretory responses to acute renal interstitial angiotensin (1-7) infusion in anaesthetised spontaneously hypertensive rats.
Autorzy:: Barry EF; Department of Physiology, University College Cork, Cork, Republic of Ireland.
O'Neill J; Department of Gastroenterology, Mercy University Hospital, Cork, Republic of Ireland.
Abdulla MH; Department of Physiology, University College Cork, Cork, Republic of Ireland.
Johns EJ; Department of Physiology, University College Cork, Cork, Republic of Ireland.; Pokaż więcej
Źródło:: Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2021 Dec; Vol. 48 (12), pp. 1674-1684. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Angiotensin I*
Peptide Fragments*

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Skocz do pozycji: 7.

Tytuł:: Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.
Autorzy:: Dang R; Institute of Clinical Pharmacy and Pharmacology, Jining First People's Hospital, Jining Medical University, Jining, China.
Yang M; Institute of Clinical Pharmacy and Pharmacology, Jining First People's Hospital, Jining Medical University, Jining, China.
Cui C; Department of Neurosurgery, Affiliated Hospital of Jining Medical University, Jining, China.
Wang C; Department of Neurosurgery, Affiliated Hospital of Jining Medical University, Jining, China.
Zhang W; Department of Pharmacy, Zhongshan Affiliated Hospital of Zhongshan University, Zhongshan, China.
Geng C; Institute of Clinical Pharmacy and Pharmacology, Jining First People's Hospital, Jining Medical University, Jining, China.
Han W; Institute of Clinical Pharmacy and Pharmacology, Jining First People's Hospital, Jining Medical University, Jining, China.
Jiang P; Institute of Clinical Pharmacy and Pharmacology, Jining First People's Hospital, Jining Medical University, Jining, China.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2021 Oct; Vol. 20 (10), pp. e13480. Date of Electronic Publication: 2021 Sep 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Angiotensin I/*therapeutic use
Angiotensin-Converting Enzyme 2/*therapeutic use
Autophagy/*drug effects
Microglia/*drug effects
Neuroinflammatory Diseases/*drug therapy
Peptide Fragments/*therapeutic use
Angiotensin I/pharmacology ; Angiotensin-Converting Enzyme 2/pharmacology ; Animals ; Humans ; Mice ; Neuroinflammatory Diseases/genetics ; Peptide Fragments/pharmacology ; Signal Transduction ; Transfection

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Skocz do pozycji: 8.

Tytuł:: Impact of CytoSorb on kinetics of vancomycin and bivalirudin in critically ill patients.
Autorzy:: Scandroglio AM; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Pieri M; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Nardelli P; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Fominskiy E; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Calabrò MG; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Melisurgo G; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Ajello S; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Pappalardo F; Department of Anesthesia and Intensive Care, IRCCS ISMETT, UPMC Italy, Palermo, Italy.; Pokaż więcej
Źródło:: Artificial organs [Artif Organs] 2021 Sep; Vol. 45 (9), pp. 1097-1103. Date of Electronic Publication: 2021 Apr 09.
Typ publikacji:: Journal Article
MeSH Terms:: Critical Illness*
Hemadsorption*
Anti-Bacterial Agents/*pharmacokinetics
Antithrombins/*pharmacokinetics
Hirudins/*pharmacokinetics
Peptide Fragments/*pharmacokinetics
Vancomycin/*pharmacokinetics
Anti-Bacterial Agents/administration & dosage ; Antithrombins/administration & dosage ; Biomarkers/blood ; Extracorporeal Membrane Oxygenation ; Female ; Hirudins/administration & dosage ; Humans ; Infusions, Intravenous ; Intensive Care Units ; Male ; Middle Aged ; Peptide Fragments/administration & dosage ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/pharmacokinetics ; Retrospective Studies ; Vancomycin/administration & dosage

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Skocz do pozycji: 9.

Tytuł:: Secondary structure dependence of amyloid-β(1-40) on simulation techniques and force field parameters.
Autorzy:: Caliskan M; Molecular Biotechnology, Turkish-German University, Istanbul, Turkey.
Mandaci SY; Molecular Biotechnology, Turkish-German University, Istanbul, Turkey.
Uversky VN; Department of Molecular Medicine, USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.; Laboratory of New Methods in Biology, Institute for Biological Instrumentation of the Russian Academy of Sciences, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, Russia.
Coskuner-Weber O; Molecular Biotechnology, Turkish-German University, Istanbul, Turkey.; Pokaż więcej
Źródło:: Chemical biology & drug design [Chem Biol Drug Des] 2021 May; Vol. 97 (5), pp. 1100-1108. Date of Electronic Publication: 2021 Feb 22.
Typ publikacji:: Journal Article
MeSH Terms:: Molecular Dynamics Simulation*
Amyloid beta-Peptides/*chemistry
Peptide Fragments/*chemistry
Amyloid beta-Peptides/metabolism ; Peptide Fragments/metabolism ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Water/chemistry

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Skocz do pozycji: 10.

Tytuł:: The chromogranin A 1-373 fragment reveals how a single change in the protein sequence exerts strong cardioregulatory effects by engaging neuropilin-1.
Autorzy:: Rocca C; Laboratory of Cellular and Molecular Cardiovascular Patho-Physiology, Department of Biology, E. and E.S., University of Calabria, Rende, Italy.
Grande F; Laboratory of Medicinal and Analytical Chemistry, Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
Granieri MC; Laboratory of Cellular and Molecular Cardiovascular Patho-Physiology, Department of Biology, E. and E.S., University of Calabria, Rende, Italy.
Colombo B; Division of Experimental Oncology, Vita-Salute San Raffaele University-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan, Italy.
De Bartolo A; Laboratory of Cellular and Molecular Cardiovascular Patho-Physiology, Department of Biology, E. and E.S., University of Calabria, Rende, Italy.; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
Giordano F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
Rago V; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
Amodio N; Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, Catanzaro, Italy.
Tota B; Laboratory of Cellular and Molecular Cardiovascular Patho-Physiology, Department of Biology, E. and E.S., University of Calabria, Rende, Italy.; Laboratory of Organ and System Physiology, Department of Biology, E. and E.S., University of Calabria, Rende, Italy.
Cerra MC; Laboratory of Organ and System Physiology, Department of Biology, E. and E.S., University of Calabria, Rende, Italy.
Rizzuti B; CNR-NANOTEC, Licryl-UOS Cosenza and CEMIF.Cal, Department of Physics, University of Calabria, Rende, Italy.
Corti A; Division of Experimental Oncology, Vita-Salute San Raffaele University-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan, Italy.
Angelone T; Laboratory of Cellular and Molecular Cardiovascular Patho-Physiology, Department of Biology, E. and E.S., University of Calabria, Rende, Italy.; National Institute of Cardiovascular Research (INRC), Bologna, Italy.
Pasqua T; Laboratory of Cellular and Molecular Cardiovascular Patho-Physiology, Department of Biology, E. and E.S., University of Calabria, Rende, Italy.; 'Fondazione Umberto Veronesi', Milan, Italy.; Pokaż więcej
Źródło:: Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2021 Apr; Vol. 231 (4), pp. e13570. Date of Electronic Publication: 2020 Nov 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Neuropilin-1*
Peptide Fragments*
Animals ; Chromogranin A ; Humans ; Molecular Docking Simulation ; Myocytes, Cardiac ; Rats

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Skocz do pozycji: 11.

Tytuł:: Outcomes of systemic bivalirudin and sodium bicarbonate purge solution for Impella 5.5.
Autorzy:: Bashline M; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
DiBridge J; Department of Pharmacy, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Klass WJ; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Morelli B; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Kaczorowski D; Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Schmidhofer M; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Horn ET; Department of Pharmacy, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Gomez H; Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Ramanan R; Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Hickey GW; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Rivosecchi RM; Department of Pharmacy, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.; Pokaż więcej
Źródło:: Artificial organs [Artif Organs] 2023 Feb; Vol. 47 (2), pp. 361-369. Date of Electronic Publication: 2022 Oct 31.
Typ publikacji:: Journal Article
MeSH Terms:: Heparin*/adverse effects
Thrombocytopenia*
Humans ; Anticoagulants/adverse effects ; Tissue Plasminogen Activator/adverse effects ; Sodium Bicarbonate ; Retrospective Studies ; Hirudins/adverse effects ; Peptide Fragments/adverse effects ; Hemorrhage/chemically induced ; Recombinant Proteins/adverse effects ; Treatment Outcome

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Skocz do pozycji: 12.

Tytuł:: Treatment with an Angiopoietin-1 mimetic peptide promotes neurological recovery after stroke in diabetic rats.
Autorzy:: Venkat P; Department of Neurology, Henry Ford Hospital, Detroit, Michigan, USA.
Ning R; Department of Neurology, Henry Ford Hospital, Detroit, Michigan, USA.
Zacharek A; Department of Neurology, Henry Ford Hospital, Detroit, Michigan, USA.
Culmone L; Department of Neurology, Henry Ford Hospital, Detroit, Michigan, USA.
Liang L; Department of Neurology, Henry Ford Hospital, Detroit, Michigan, USA.
Landschoot-Ward J; Department of Neurology, Henry Ford Hospital, Detroit, Michigan, USA.
Chopp M; Department of Neurology, Henry Ford Hospital, Detroit, Michigan, USA.; Department of Physics, Oakland University, Rochester, Michigan, USA.; Pokaż więcej
Źródło:: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2021 Jan; Vol. 27 (1), pp. 48-59. Date of Electronic Publication: 2020 Dec 21.
Typ publikacji:: Journal Article
MeSH Terms:: Angiopoietin-1/*therapeutic use
Biomimetic Materials/*therapeutic use
Diabetes Mellitus, Experimental/*drug therapy
Peptide Fragments/*therapeutic use
Recovery of Function/*drug effects
Stroke/*drug therapy
Angiopoietin-1/pharmacology ; Animals ; Biomimetic Materials/pharmacology ; Cells, Cultured ; Diabetes Mellitus, Experimental/pathology ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Peptide Fragments/pharmacology ; Pregnancy ; Rats ; Rats, Wistar ; Recovery of Function/physiology ; Stroke/pathology ; Treatment Outcome

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Skocz do pozycji: 13.

Tytuł:: A meta-analysis on association between CSN3 gene variants and milk yield and composition in cattle.
Autorzy:: Mahmoudi P; Department of Animal Science, Faculty of Agriculture, University of Kurdistan, P.O. Box 416, Sanandaj, Kurdistan, Iran.
Rostamzadeh J; Department of Animal Science, Faculty of Agriculture, University of Kurdistan, P.O. Box 416, Sanandaj, Kurdistan, Iran.
Rashidi A; Department of Animal Science, Faculty of Agriculture, University of Kurdistan, P.O. Box 416, Sanandaj, Kurdistan, Iran.
Zergani E; Department of Animal Science, Faculty of Agriculture, University of Kurdistan, P.O. Box 416, Sanandaj, Kurdistan, Iran.
Razmkabir M; Department of Animal Science, Faculty of Agriculture, University of Kurdistan, P.O. Box 416, Sanandaj, Kurdistan, Iran.; Pokaż więcej
Źródło:: Animal genetics [Anim Genet] 2020 Jun; Vol. 51 (3), pp. 369-381. Date of Electronic Publication: 2020 Feb 18.
Typ publikacji:: Journal Article; Meta-Analysis
MeSH Terms:: Polymorphism, Genetic*
Caseins/*genetics
Cattle/*genetics
Milk/*metabolism
Peptide Fragments/*genetics
Animals ; Caseins/metabolism ; Cattle/metabolism ; Milk/chemistry ; Peptide Fragments/metabolism

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Skocz do pozycji: 14.

Tytuł:: Randomised clinical trial: a placebo-controlled study of subcutaneous or intradermal NEXVAX2, an investigational immunomodulatory peptide therapy for coeliac disease.
Autorzy:: Truitt KE; ImmusanT, Inc., Cambridge, Massachusetts, USA.
Daveson AJM; University of Queensland, Brisbane, Queensland, Australia.
Ee HC; Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
Goel G; ImmusanT, Inc., Cambridge, Massachusetts, USA.
MacDougall J; Prometrika, LLC, Cambridge, Massachusetts, USA.
Neff K; ImmusanT, Inc., Cambridge, Massachusetts, USA.
Anderson RP; ImmusanT, Inc., Cambridge, Massachusetts, USA.; Pokaż więcej
Źródło:: Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2019 Sep; Vol. 50 (5), pp. 547-555. Date of Electronic Publication: 2019 Aug 13.
Typ publikacji:: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:: Celiac Disease/*drug therapy
Drugs, Investigational/*administration & dosage
Drugs, Investigational/*pharmacokinetics
Glutens/*administration & dosage
Glutens/*pharmacokinetics
Peptide Fragments/*administration & dosage
Peptide Fragments/*pharmacokinetics
Adolescent ; Adult ; Biological Availability ; Celiac Disease/metabolism ; Child ; Dose-Response Relationship, Drug ; Double-Blind Method ; Drugs, Investigational/adverse effects ; Female ; Glutens/adverse effects ; Humans ; Immunomodulation ; Injections, Intradermal ; Injections, Subcutaneous ; Male ; Middle Aged ; Peptide Fragments/adverse effects ; Placebos ; Young Adult

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Skocz do pozycji: 15.

Tytuł:: Therapeutic effects of carvacrol on beta-amyloid-induced impairments in in vitro and in vivo models of Alzheimer's disease.
Autorzy:: Celik Topkara K; Department of Physiology, Recep Tayyip Erdogan University, Rize, Turkey.
Kilinc E; Department of Physiology, Bolu Abant Izzet Baysal University, Bolu, Turkey.
Cetinkaya A; Department of Physiology, Bolu Abant Izzet Baysal University, Bolu, Turkey.
Saylan A; Department of Histology and Embryology, Bolu Abant Izzet Baysal University, Bolu, Turkey.
Demir S; Department of Physiology, Duzce University, Duzce, Turkey.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2022 Nov; Vol. 56 (9), pp. 5714-5726. Date of Electronic Publication: 2021 Dec 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alzheimer Disease*/drug therapy
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Neuroblastoma*/drug therapy
Humans ; Animals ; Rats ; Amyloid beta-Peptides/toxicity ; Amyloid beta-Peptides/metabolism ; Galantamine/adverse effects ; Peptide Fragments/pharmacology ; Hippocampus/metabolism ; Memory Disorders ; Oxidative Stress ; Superoxide Dismutase ; Thymol

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Skocz do pozycji: 16.

Tytuł:: Cognitive functioning, cerebrospinal fluid Alzheimer's disease biomarkers and cerebral glucose metabolism in late-onset epilepsy of unknown aetiology: A prospective study.
Autorzy:: Fernandes M; Epilepsy Centre, Neurology Unit, Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Manfredi N; Epilepsy Centre, Neurology Unit, Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Aluisantonio L; Epilepsy Centre, Neurology Unit, Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Franchini F; IRCCS Fondazione Santa Lucia, Rome, Italy.
Chiaravalloti A; Department of Biomedicine and Prevention, University of Rome 'Tor Vergata', Rome, Italy.; IRCCS Neuromed, Pozzilli, Italy.
Izzi F; Epilepsy Centre, Neurology Unit, Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Di Santo S; IRCCS Fondazione Santa Lucia, Rome, Italy.
Schillaci O; Department of Biomedicine and Prevention, University of Rome 'Tor Vergata', Rome, Italy.; IRCCS Neuromed, Pozzilli, Italy.
Mercuri NB; Epilepsy Centre, Neurology Unit, Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.; IRCCS Fondazione Santa Lucia, Rome, Italy.
Placidi F; Epilepsy Centre, Neurology Unit, Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Liguori C; Epilepsy Centre, Neurology Unit, Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2022 Nov; Vol. 56 (9), pp. 5384-5396. Date of Electronic Publication: 2022 Jun 18.
Typ publikacji:: Journal Article
MeSH Terms:: Alzheimer Disease*/metabolism
Cognitive Dysfunction*
Epilepsy*
Humans ; Aged ; tau Proteins/cerebrospinal fluid ; Prospective Studies ; Amyloid beta-Peptides/metabolism ; Cognition ; Fluorodeoxyglucose F18 ; Positron-Emission Tomography/methods ; Biomarkers/metabolism ; Glucose ; Peptide Fragments/cerebrospinal fluid

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Skocz do pozycji: 17.

Tytuł:: Heparin vs bivalirudin anticoagulation for extracorporeal membrane oxygenation.
Autorzy:: Kaseer H; Department of Pharmacy, Mayo Clinic, Jacksonville, Florida.; Department of Pharmacy, UF Health Shands Hospital, Gainesville, Florida.
Soto-Arenall M; Department of Pharmacy, Mayo Clinic, Jacksonville, Florida.
Sanghavi D; Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.
Moss J; Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.
Ratzlaff R; Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.
Pham S; Department of Cardiothoracic Surgery, Mayo Clinic, Jacksonville, Florida.
Guru P; Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.; Pokaż więcej
Źródło:: Journal of cardiac surgery [J Card Surg] 2020 Apr; Vol. 35 (4), pp. 779-786. Date of Electronic Publication: 2020 Feb 12.
Typ publikacji:: Comparative Study; Journal Article; Observational Study
MeSH Terms:: Anticoagulants/*administration & dosage
Extracorporeal Membrane Oxygenation/*adverse effects
Heparin/*administration & dosage
Hirudins/*administration & dosage
Peptide Fragments/*administration & dosage
Thrombosis/*etiology
Thrombosis/*prevention & control
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anticoagulants/adverse effects ; Female ; Heparin/adverse effects ; Hirudins/adverse effects ; Humans ; Male ; Middle Aged ; Peptide Fragments/adverse effects ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/adverse effects ; Retrospective Studies ; Thrombocytopenia/chemically induced ; Young Adult

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Skocz do pozycji: 18.

Tytuł:: Impact of lymphoma-linked Asn11Tyr point mutation on the interaction between Bcl-2 and a BH3 mimetic: Insights from molecular dynamics simulation.
Autorzy:: Singh K; Department of Biology and Biochemistry, University of Houston, Houston, TX, USA.
Briggs JM; Department of Biology and Biochemistry, University of Houston, Houston, TX, USA.; Pokaż więcej
Źródło:: Chemical biology & drug design [Chem Biol Drug Des] 2020 Apr; Vol. 95 (4), pp. 435-450. Date of Electronic Publication: 2020 Feb 06.
Typ publikacji:: Journal Article
MeSH Terms:: Biomimetic Materials/*chemistry
Lymphoma/*metabolism
Peptide Fragments/*metabolism
Proto-Oncogene Proteins/*metabolism
Proto-Oncogene Proteins c-bcl-2/*metabolism
Amino Acid Sequence ; Apoptosis/drug effects ; Apoptosis Regulatory Proteins/metabolism ; Humans ; Hydrophobic and Hydrophilic Interactions ; Molecular Dynamics Simulation ; Mutation ; Peptide Fragments/chemistry ; Point Mutation ; Protein Binding ; Protein Domains ; Thermodynamics

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Skocz do pozycji: 19.

Tytuł:: N-locking stabilization of covalent helical peptides: Application to Bfl-1 antagonists.
Autorzy:: Baggio C; Division of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA, USA.
Udompholkul P; Division of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA, USA.
Gambini L; Division of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA, USA.
Jossart J; Department of Biochemistry, College of Natural and Agricultural Sciences, University of California Riverside, Riverside, CA, USA.
Salem AF; Division of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA, USA.
Håkansson M; SARomics Biostructures AB, Lund, Sweden.
Perry JJP; Department of Biochemistry, College of Natural and Agricultural Sciences, University of California Riverside, Riverside, CA, USA.
Pellecchia M; Division of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA, USA.; Pokaż więcej
Źródło:: Chemical biology & drug design [Chem Biol Drug Des] 2020 Apr; Vol. 95 (4), pp. 412-426. Date of Electronic Publication: 2020 Jan 20.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis Regulatory Proteins/*chemistry
Forkhead Transcription Factors/*chemistry
Nerve Tissue Proteins/*chemistry
Peptide Fragments/*chemistry
Proto-Oncogene Proteins/*chemistry
Amino Acid Sequence ; Apoptosis Regulatory Proteins/pharmacokinetics ; Crystallization ; Forkhead Transcription Factors/metabolism ; Humans ; Models, Molecular ; Nerve Tissue Proteins/metabolism ; Peptide Fragments/metabolism ; Protein Binding ; Protein Conformation ; Proto-Oncogene Proteins/metabolism

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Skocz do pozycji: 20.

Tytuł:: Aging-induced Akt activation involves in aging-related pathologies and Aβ-induced toxicity.
Autorzy:: Chen YR; Department of Pharmacology, National Cheng-Kung University, Tainan, Taiwan.
Li YH; Department of Pharmacology, National Cheng-Kung University, Tainan, Taiwan.
Hsieh TC; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wang CM; School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Cheng KC; Department of Pharmacology, National Cheng-Kung University, Tainan, Taiwan.; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wang L; College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.
Lin TY; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Cheung CHA; Department of Pharmacology, National Cheng-Kung University, Tainan, Taiwan.; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wu CL; Department of Biochemistry and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Department of Neurology, Chang Gung Memorial Hospital, Linkou, Taiwan.
Chiang H; Department of Pharmacology, National Cheng-Kung University, Tainan, Taiwan.; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2019 Aug; Vol. 18 (4), pp. e12989. Date of Electronic Publication: 2019 Jun 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Aging/*metabolism
Alzheimer Disease/*metabolism
Amyloid beta-Peptides/*metabolism
Drosophila melanogaster/*metabolism
Peptide Fragments/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Aging/pathology ; Alzheimer Disease/pathology ; Amyloid Precursor Protein Secretases/metabolism ; Amyloid beta-Peptides/genetics ; Animals ; Animals, Genetically Modified ; Cell Survival/genetics ; Cyclic AMP/metabolism ; Disease Models, Animal ; Drosophila Proteins/metabolism ; Drosophila melanogaster/genetics ; Locomotion/genetics ; Longevity/genetics ; Neurons/metabolism ; Peptide Fragments/genetics ; Proto-Oncogene Proteins c-akt/genetics ; RNA Interference ; Receptors, Notch/metabolism

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