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Wyszukujesz frazę ""Peptide Hydrolases"" wg kryterium: Temat


Tytuł:
Exploring bi-carbazole-linked triazoles as inhibitors of prolyl endo peptidase via integrated in vitro and in silico study.
Autorzy:
Ullah S; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan.
Mansoor F; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan.
Khan SA; Tunneling Group, Biotechnology Centre, Doctoral School, Silesian University of Technology, Akademicka 2, 44-100, Gliwice, Poland. .
Jabeen U; Department of Biochemistry, Federal Urdu University of Karachi, Gulshan-e-Iqbal, Karachi, 75300, Pakistan.
Almars AI; Department of Medial Laboratory Sciences, Faculty of Applied Medical Science, King Abdulaziz University, 21589, Jeddah, Saudi Arabia.
Almohaimeed HM; Department of Basic Science, College of Medicine, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, 11671, Riyadh, Saudi Arabia.
Basri AM; Department of Medial Laboratory Sciences, Faculty of Applied Medical Science, King Abdulaziz University, 21589, Jeddah, Saudi Arabia.
Alshabrmi FM; Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, 51452, Buraydah, Saudi Arabia.
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Źródło:
Scientific reports [Sci Rep] 2024 Apr 01; Vol. 14 (1), pp. 7675. Date of Electronic Publication: 2024 Apr 01.
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Hydrolases*
Triazoles*/pharmacology
Triazoles*/chemistry
Prolyl Oligopeptidases ; Serine Endopeptidases ; Carbazoles ; Structure-Activity Relationship ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł:
SENP1 attenuates hypoxia‑reoxygenation injury in liver sinusoid endothelial cells by relying on the HIF‑1α signaling pathway.
Autorzy:
Qing Z; General Surgery Department, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
Luo Q; Department of Pediatrics, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
Duan J; General Surgery Department, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
Lin J; Organ Transplantation Center, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
Huang H; Organ Transplantation Center, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
Yang S; Organ Transplantation Center, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
Zeng Z; Organ Transplantation Center, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2024 Apr; Vol. 29 (4). Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Endothelial Cells*/metabolism
Peptide Hydrolases*
Animals ; Mice ; Capillaries/metabolism ; Cell Hypoxia ; Hypoxia/metabolism ; Liver/metabolism ; Signal Transduction ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł:
Aspergillus fumigatus secretes a protease(s) that displays in silico binding affinity towards the SARS-CoV-2 spike protein and mediates SARS-CoV-2 pseudovirion entry into HEK-293T cells.
Autorzy:
Mjokane N; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, 9301, Bloemfontein, South Africa.
Akintemi EO; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, 9301, Bloemfontein, South Africa.
Sabiu S; Department of Biotechnology and Food Science, Faculty of Applied Science, Durban University of Technology, 4000, Durban, P.O. Box 1334, South Africa.
Gcilitshana OMN; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, 9301, Bloemfontein, South Africa.
Albertyn J; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, 9301, Bloemfontein, South Africa.
Pohl CH; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, 9301, Bloemfontein, South Africa.
Sebolai OM; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, 9301, Bloemfontein, South Africa. .
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Źródło:
Virology journal [Virol J] 2024 Mar 06; Vol. 21 (1), pp. 58. Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Hydrolases*
COVID-19*
Humans ; Spike Glycoprotein, Coronavirus ; Aspergillus fumigatus ; SARS-CoV-2 ; HEK293 Cells ; Molecular Docking Simulation ; Peptides
Czasopismo naukowe
Tytuł:
Regulation of developmental gatekeeping and cell fate transition by the calpain protease DEK1 in Physcomitrium patens.
Autorzy:
Demko V; Department of Plant Sciences, Norwegian University of Life Sciences, P.O. Box 5003, NO-1432, Ås, Norway.; Department of Plant Physiology, Faculty of Natural Sciences, Comenius University in Bratislava, Ilkovicova 6, 84104, Bratislava, Slovakia.; Plant Science and Biodiversity Center, Slovak Academy of Sciences, Dubravska cesta 9, 84104, Bratislava, Slovakia.
Belova T; Department of Plant Sciences, Norwegian University of Life Sciences, P.O. Box 5003, NO-1432, Ås, Norway.; Centre for Molecular Medicine Norway, University of Oslo, Oslo, Norway.
Messerer M; Plant Genome and Systems Biology, Helmholtz Center Munich-Research Center for Environmental Health, 85764, Neuherberg, Germany.
Hvidsten TR; Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Perroud PF; Institut Jean-Pierre Bourgin, INRAE, AgroParisTech, Université Paris-Saclay, 78000, Versailles, France.
Ako AE; Department of Biotechnology, Inland Norway University of Applied Sciences, Holsetgata 31, 2318, Hamar, Norway.; School of Animal, Rural and Environmental Sciences, Nottingham Trent University, Brackenhurst Campus, Southwell, Nottinghamshire, NG25 0QF, UK.
Johansen W; Department of Biotechnology, Inland Norway University of Applied Sciences, Holsetgata 31, 2318, Hamar, Norway.
Mayer KFX; Plant Genome and Systems Biology, Helmholtz Center Munich-Research Center for Environmental Health, 85764, Neuherberg, Germany.; School of Life Sciences, Technical University Munich, 85354, Freising, Germany.
Olsen OA; Department of Plant Sciences, Norwegian University of Life Sciences, P.O. Box 5003, NO-1432, Ås, Norway.
Lang D; Plant Genome and Systems Biology, Helmholtz Center Munich-Research Center for Environmental Health, 85764, Neuherberg, Germany. .; Bundeswehr Institute of Microbiology, Microbial Genomics and Bioforensics, 80937, Munich, Germany. .
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Źródło:
Communications biology [Commun Biol] 2024 Mar 04; Vol. 7 (1), pp. 261. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Hydrolases*
Bryopsida*
Humans ; Calpain/genetics ; Endopeptidases ; Cell Differentiation/genetics
Czasopismo naukowe
Tytuł:
Recent Advances on Targeting Proteases for Antiviral Development.
Autorzy:
Borges PHO; Laboratory of Organic Synthesis and Biological Prospecting, Chemistry Institute, Federal University of Rio de Janeiro, Rio de Janeiro 21941-909, Brazil.; Laboratory of Experimental and Computational Biochemistry of Drugs, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, Brazil.
Ferreira SB; Laboratory of Organic Synthesis and Biological Prospecting, Chemistry Institute, Federal University of Rio de Janeiro, Rio de Janeiro 21941-909, Brazil.
Silva FP Jr; Laboratory of Experimental and Computational Biochemistry of Drugs, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, Brazil.
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Źródło:
Viruses [Viruses] 2024 Feb 27; Vol. 16 (3). Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Peptide Hydrolases*/metabolism
Antiviral Agents*/therapeutic use
Humans ; Endopeptidases ; SARS-CoV-2/metabolism ; Viral Proteases
Czasopismo naukowe
Tytuł:
The major role of sarA in limiting Staphylococcus aureus extracellular protease production in vitro is correlated with decreased virulence in diverse clinical isolates in osteomyelitis.
Autorzy:
Campbell MJ; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Beenken KE; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Ramirez AM; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Smeltzer MS
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Źródło:
Virulence [Virulence] 2023 Dec; Vol. 14 (1), pp. 2175496.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptide Hydrolases*/genetics
Peptide Hydrolases*/metabolism
Osteomyelitis*
Animals ; Humans ; Mice ; Virulence ; Staphylococcus aureus ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Endopeptidases/genetics ; Gene Expression Regulation, Bacterial ; Biofilms ; Mutation
Czasopismo naukowe
Tytuł:
Svx Peptidases of Phytopathogenic Pectolytic Bacteria: Structural, Catalytic and Phytoimmune Properties.
Autorzy:
Tendiuk N; Kazan Institute of Biochemistry and Biophysics, FRC Kazan Scientific Center of RAS, 420111 Kazan, Russia.
Diakonova A; Kazan Institute of Biochemistry and Biophysics, FRC Kazan Scientific Center of RAS, 420111 Kazan, Russia.
Petrova O; Kazan Institute of Biochemistry and Biophysics, FRC Kazan Scientific Center of RAS, 420111 Kazan, Russia.
Mukhametzyanov T; Department of Physical Chemistry, Kazan Federal University, 420008 Kazan, Russia.
Makshakova O; Kazan Institute of Biochemistry and Biophysics, FRC Kazan Scientific Center of RAS, 420111 Kazan, Russia.
Gorshkov V; Kazan Institute of Biochemistry and Biophysics, FRC Kazan Scientific Center of RAS, 420111 Kazan, Russia.; Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 07; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 07.
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Hydrolases*
Bacteria*
Biological Assay ; Biological Transport ; Catalysis ; Dickeya
Czasopismo naukowe
Tytuł:
Computer-Aided Prediction of the Interactions of Viral Proteases with Antiviral Drugs: Antiviral Potential of Broad-Spectrum Drugs.
Autorzy:
Ren P; School of Life Science and Technology, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai 201210, China.
Li S; School of Life Science and Technology, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai 201210, China.
Wang S; School of Life Science and Technology, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai 201210, China.
Zhang X; School of Life Science and Technology, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai 201210, China.
Bai F; School of Life Science and Technology, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai 201210, China.; School of Information Science and Technology, ShanghaiTech University, Shanghai 201210, China.; Shanghai Clinical Research and Trial Center, Shanghai 201210, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Dec 31; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 31.
Typ publikacji:
Journal Article
MeSH Terms:
Viral Proteases*
Peptide Hydrolases*
Humans ; Aspartic Acid Endopeptidases ; Computers ; Protease Inhibitors/pharmacology ; Antiviral Agents/pharmacology
Czasopismo naukowe
Tytuł:
Cellular and Enzymatic Determinants Impacting the Exolytic Action of an Anti-Staphylococcal Enzybiotic.
Autorzy:
Gouveia A; Phage Biology Research and Infection Control (PhaBRIC), Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.
Pinto D; Phage Biology Research and Infection Control (PhaBRIC), Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.
Vítor JMB; Pathogen Genome Bioinformatics and Computational Biology, Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.
São-José C; Phage Biology Research and Infection Control (PhaBRIC), Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 30; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 30.
Typ publikacji:
Journal Article
MeSH Terms:
Staphylococcus*
Peptide Hydrolases*
Amidohydrolases ; Anti-Bacterial Agents ; Bacteriolysis
Czasopismo naukowe
Tytuł:
Regulation of Peptidase Activity beyond the Active Site in Human Health and Disease.
Autorzy:
Obaha A; Faculty of Chemistry and Chemical Technology, Department of Chemistry and Biochemistry, University of Ljubljana, Večna pot 113, SI-1000 Ljubljana, Slovenia.
Novinec M; Faculty of Chemistry and Chemical Technology, Department of Chemistry and Biochemistry, University of Ljubljana, Večna pot 113, SI-1000 Ljubljana, Slovenia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 04; Vol. 24 (23). Date of Electronic Publication: 2023 Dec 04.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Glycosaminoglycans*
Peptide Hydrolases*
Humans ; Catalytic Domain ; Allosteric Site ; Proteolysis ; Binding Sites ; Allosteric Regulation
Czasopismo naukowe
Tytuł:
Combined NMR and molecular dynamics conformational filter identifies unambiguously dynamic ensembles of Dengue protease NS2B/NS3pro.
Autorzy:
Agback T; Department of Molecular Sciences, Swedish University of Agricultural Sciences, PO Box 7015, SE-750 07, Uppsala, Sweden.
Lesovoy D; Department of Structural Biology, Shemyakin-Ovchinnikov, Institute of Bioorganic Chemistry RAS, 117997, Moscow, Russia.; Swedish NMR Centre, University of Gothenburg, Box 465, 40530, Gothenburg, Sweden.
Han X; Science for Life Laboratory, Department of Medicine, Karolinska Institute, and Division of Infectious Diseases, Karolinska University Hospital, SE-171 76, Stockholm, Sweden.
Lomzov A; Laboratory of Structural Biology, Institute of Chemical Biology and Fundamental Medicine SB RAS, 630090, Novosibirsk, Russia.
Sun R; Science for Life Laboratory, Department of Medicine, Karolinska Institute, and Division of Infectious Diseases, Karolinska University Hospital, SE-171 76, Stockholm, Sweden.
Sandalova T; Science for Life Laboratory, Department of Medicine, Karolinska Institute, and Division of Infectious Diseases, Karolinska University Hospital, SE-171 76, Stockholm, Sweden.
Orekhov VY; Swedish NMR Centre, University of Gothenburg, Box 465, 40530, Gothenburg, Sweden.; Department of Chemistry and Molecular Biology, University of Gothenburg, Box 465, 40530, Gothenburg, Sweden.
Achour A; Science for Life Laboratory, Department of Medicine, Karolinska Institute, and Division of Infectious Diseases, Karolinska University Hospital, SE-171 76, Stockholm, Sweden. .
Agback P; Department of Molecular Sciences, Swedish University of Agricultural Sciences, PO Box 7015, SE-750 07, Uppsala, Sweden. .
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Źródło:
Communications biology [Commun Biol] 2023 Nov 24; Vol. 6 (1), pp. 1193. Date of Electronic Publication: 2023 Nov 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptide Hydrolases*
Dengue*
Humans ; Serine Endopeptidases/chemistry ; Molecular Dynamics Simulation ; Protein Conformation ; Viral Nonstructural Proteins/chemistry
Czasopismo naukowe
Tytuł:
A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile.
Autorzy:
Marini E; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República EAN, Oeiras, Portugal.
Olivença C; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República EAN, Oeiras, Portugal.
Ramalhete S; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República EAN, Oeiras, Portugal.
Aguirre AM; Texas A&M University, Department of Biology, College Station, Texas, United States of America.
Ingle P; Clostridia Research Group, BBSRC/EPSRC Synthetic Biology Research Centre (SBRC), School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Melo MN; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República EAN, Oeiras, Portugal.
Antunes W; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República EAN, Oeiras, Portugal.
Minton NP; Clostridia Research Group, BBSRC/EPSRC Synthetic Biology Research Centre (SBRC), School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Hernandez G; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República EAN, Oeiras, Portugal.
Cordeiro TN; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República EAN, Oeiras, Portugal.
Sorg JA; Texas A&M University, Department of Biology, College Station, Texas, United States of America.
Serrano M; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República EAN, Oeiras, Portugal.
Henriques AO; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República EAN, Oeiras, Portugal.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Nov 13; Vol. 19 (11), pp. e1011741. Date of Electronic Publication: 2023 Nov 13 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Hydrolases*/metabolism
Clostridioides difficile*/genetics
Clostridioides difficile*/metabolism
Humans ; Clostridioides ; Spores, Bacterial/metabolism ; Transcription Factors/metabolism ; Endopeptidases/metabolism ; Bacterial Proteins/metabolism ; Bacillus subtilis/metabolism
Czasopismo naukowe
Tytuł:
Structure-activity studies of Streptococcus pyogenes enzyme SpyCEP reveal high affinity for CXCL8 in the SpyCEP C-terminal.
Autorzy:
Pearson M; Department of Infectious Disease, Imperial College London, London, W12 0NN, UK.; Centre for Bacterial Resistance Biology, Imperial College London, London, SW7 2AZ, UK.
Haslam C; GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
Fosberry A; GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
Jones EJ; GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
Reglinski M; Department of Infectious Disease, Imperial College London, London, W12 0NN, UK.
Reeves L; Department of Infectious Disease, Imperial College London, London, W12 0NN, UK.
Edwards RJ; Department of Medicine, Imperial College London, London, W12 0NN, UK.
Lawrenson RA; Department of Infectious Disease, Imperial College London, London, W12 0NN, UK.
Brown JC; Department of Infectious Disease, Imperial College London, London, W12 0NN, UK.
Mossakowska D; GlaxoSmithKline R&D, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.; Malopolska Centre of Biotechnology, Jagiellonian University, 30-387, Kraków, Poland.
Pease JE; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK. .
Sriskandan S; Department of Infectious Disease, Imperial College London, London, W12 0NN, UK. .; Centre for Bacterial Resistance Biology, Imperial College London, London, SW7 2AZ, UK. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 03; Vol. 13 (1), pp. 19052. Date of Electronic Publication: 2023 Nov 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Streptococcus pyogenes*/metabolism
Peptide Hydrolases*/metabolism
Protein Domains
Czasopismo naukowe
Tytuł:
ClpP/ClpX deficiency impairs mitochondrial functions and mTORC1 signaling during spermatogenesis.
Autorzy:
Guo C; Shenzhen Key Laboratory of Fertility Regulation, Reproductive Medicine Center, The University of Hong Kong-Shenzhen Hospital, Shenzhen, 518053, China. .; Center for Energy Metabolism and Reproduction, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. .
Xiao Y; Shenzhen Key Laboratory of Fertility Regulation, Reproductive Medicine Center, The University of Hong Kong-Shenzhen Hospital, Shenzhen, 518053, China.
Gu J; Shenzhen Key Laboratory of Fertility Regulation, Reproductive Medicine Center, The University of Hong Kong-Shenzhen Hospital, Shenzhen, 518053, China.
Zhao P; Shenzhen Key Laboratory of Fertility Regulation, Reproductive Medicine Center, The University of Hong Kong-Shenzhen Hospital, Shenzhen, 518053, China.
Hu Z; Department of Obstetrics and Gynaecology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, 999077, China.
Zheng J; Department of Obstetrics and Gynaecology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, 999077, China.
Hua R; Shenzhen Key Laboratory of Fertility Regulation, Reproductive Medicine Center, The University of Hong Kong-Shenzhen Hospital, Shenzhen, 518053, China.; Center for Energy Metabolism and Reproduction, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Hai Z; Shenzhen Key Laboratory of Fertility Regulation, Reproductive Medicine Center, The University of Hong Kong-Shenzhen Hospital, Shenzhen, 518053, China.
Su J; Shenzhen Key Laboratory of Fertility Regulation, Reproductive Medicine Center, The University of Hong Kong-Shenzhen Hospital, Shenzhen, 518053, China.
Zhang JV; Center for Energy Metabolism and Reproduction, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.; Shenzhen Key Laboratory of Metabolic Health, Shenzhen, 518055, China.
Yeung WSB; Shenzhen Key Laboratory of Fertility Regulation, Reproductive Medicine Center, The University of Hong Kong-Shenzhen Hospital, Shenzhen, 518053, China.; Department of Obstetrics and Gynaecology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, 999077, China.
Wang T; Shenzhen Key Laboratory of Fertility Regulation, Reproductive Medicine Center, The University of Hong Kong-Shenzhen Hospital, Shenzhen, 518053, China. .
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Źródło:
Communications biology [Commun Biol] 2023 Oct 05; Vol. 6 (1), pp. 1012. Date of Electronic Publication: 2023 Oct 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mitochondria*/metabolism
Peptide Hydrolases*/metabolism
Endopeptidase Clp*/metabolism
Animals ; Male ; Mice ; Serine Endopeptidases/metabolism ; Spermatocytes/metabolism ; Spermatogenesis
Czasopismo naukowe
Tytuł:
Species-specific cleavage of cGAS by picornavirus protease 3C disrupts mitochondria DNA-mediated immune sensing.
Autorzy:
Yan Y; National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Wu L; National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Yuan Y; National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Wang H; State Key Laboratory of Animal Disease Control, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Yin H; National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Li M; National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Chai L; National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Liang R; Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Liu Y; College of Animal Sciences, Shanxi Agricultural University, Jinzhong, China.
Zhao D; State Key Laboratory of Animal Disease Control, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Xing J; Department of Surgery and Immunobiology and Transplant Science Center, Houston Methodist Research Institute, Houston Methodist, Houston, Texas, United States of America.; Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston Methodist, Houston, Texas, United States of America.
Li P; Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America.
Li X; National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University, Beijing, China.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Sep 14; Vol. 19 (9), pp. e1011641. Date of Electronic Publication: 2023 Sep 14 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptide Hydrolases*
Picornaviridae*/physiology
Nucleotidyltransferases*/metabolism
Animals ; Humans ; Mice ; DNA, Mitochondrial ; Endopeptidases ; Mitochondria ; Swine
SCR Organism:
Senecavirus A
Czasopismo naukowe
Tytuł:
Non-Canonical Amino Acids in Analyses of Protease Structure and Function.
Autorzy:
Goettig P; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Paracelsus Medical University, Strubergasse 21, 5020 Salzburg, Austria.
Koch NG; Biocatalysis Group, Technische Universität Berlin, 10623 Berlin, Germany.; Bioanalytics Group, Institute of Biotechnology, Technische Universität Berlin, 10623 Berlin, Germany.
Budisa N; Bioanalytics Group, Institute of Biotechnology, Technische Universität Berlin, 10623 Berlin, Germany.; Department of Chemistry, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 13; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Peptide Hydrolases*
Antifibrinolytic Agents*
Amino Acids ; Endopeptidases ; Proteolysis
Czasopismo naukowe
Tytuł:
Small Molecules Targeting 3C Protease Inhibit FMDV Replication and Exhibit Virucidal Effect in Cell-Based Assays.
Autorzy:
Theerawatanasirikul S; Department of Anatomy, Faculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand.
Lueangaramkul V; Department of Microbiology and Immunology, Faculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand.
Pantanam A; Department of Microbiology and Immunology, Faculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand.
Mana N; Department of Microbiology and Immunology, Faculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand.
Semkum P; Department of Microbiology and Immunology, Faculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand.
Lekcharoensuk P; Department of Microbiology and Immunology, Faculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand.; Center of Advanced Studies in Agriculture and Food, KU Institute, Bangkok 10900, Thailand.
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Źródło:
Viruses [Viruses] 2023 Sep 06; Vol. 15 (9). Date of Electronic Publication: 2023 Sep 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptide Hydrolases*
Foot-and-Mouth Disease Virus*
Animals ; Molecular Docking Simulation ; Endopeptidases ; Antiviral Agents/pharmacology ; 3C Viral Proteases
Czasopismo naukowe
Tytuł:
Attenuation of Oxidative Damage via Upregulating Nrf2/HO-1 Signaling Pathway by Protease SH21 with Exerting Anti-Inflammatory and Anticancer Properties In Vitro.
Autorzy:
Tarek H; Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju 61452, Republic of Korea.
Cho SS; Department of Pharmacy, College of Pharmacy, Mokpo National University, Muan 58554, Republic of Korea.; Department of Biomedicine, Health & Life Convergence Sciences, BK21 Four, Biomedical and Healthcare Research Institute, Mokpo National University, Muan 58554, Republic of Korea.
Hossain MS; Department of Biomedical Sciences, Chosun University, Gwangju 61452, Republic of Korea.
Yoo JC; Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju 61452, Republic of Korea.
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Źródło:
Cells [Cells] 2023 Sep 01; Vol. 12 (17). Date of Electronic Publication: 2023 Sep 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
NF-E2-Related Factor 2*
Peptide Hydrolases*
Humans ; Endopeptidases ; Heme Oxygenase-1 ; Inflammation/drug therapy ; Oxidative Stress ; Signal Transduction
Czasopismo naukowe
Tytuł:
Glycosylation Contributes to Thermostability and Proteolytic Resistance of rFIP-nha ( Nectria haematococca ).
Autorzy:
Liu Y; Laboratory of Biomanufacturing and Food Engineering, Institute of Food Science and Technology, Chinese Academy of Agriculture Sciences, Beijing 100193, China.; Wageningen Food and Biobased Research, Wageningen University and Research, 6708 WG Wageningen, The Netherlands.; Laboratory of Food Chemistry, Wageningen University, 6708 WG Wageningen, The Netherlands.
Hoppenbrouwers T; Wageningen Food and Biobased Research, Wageningen University and Research, 6708 WG Wageningen, The Netherlands.; Laboratory of Food Quality and Design, Wageningen University, 6708 WG Wageningen, The Netherlands.
Wang Y; Laboratory of Biomanufacturing and Food Engineering, Institute of Food Science and Technology, Chinese Academy of Agriculture Sciences, Beijing 100193, China.
Xie Y; Laboratory of Biomanufacturing and Food Engineering, Institute of Food Science and Technology, Chinese Academy of Agriculture Sciences, Beijing 100193, China.; Beijing SeekGene BioSciences Co., Ltd., Beijing 102206, China.
Wei X; Laboratory of Biomanufacturing and Food Engineering, Institute of Food Science and Technology, Chinese Academy of Agriculture Sciences, Beijing 100193, China.
Zhang H; Laboratory of Biomanufacturing and Food Engineering, Institute of Food Science and Technology, Chinese Academy of Agriculture Sciences, Beijing 100193, China.
Du G; Laboratory of Biomanufacturing and Food Engineering, Institute of Food Science and Technology, Chinese Academy of Agriculture Sciences, Beijing 100193, China.
Imam KMSU; Laboratory of Biomanufacturing and Food Engineering, Institute of Food Science and Technology, Chinese Academy of Agriculture Sciences, Beijing 100193, China.
Wichers H; Wageningen Food and Biobased Research, Wageningen University and Research, 6708 WG Wageningen, The Netherlands.; Laboratory of Food Chemistry, Wageningen University, 6708 WG Wageningen, The Netherlands.
Li Z; Laboratory of Biomanufacturing and Food Engineering, Institute of Food Science and Technology, Chinese Academy of Agriculture Sciences, Beijing 100193, China.
Bastiaan-Net S; Wageningen Food and Biobased Research, Wageningen University and Research, 6708 WG Wageningen, The Netherlands.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Aug 31; Vol. 28 (17). Date of Electronic Publication: 2023 Aug 31.
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Hydrolases*
Fusarium*
Glycosylation ; Proteolysis ; Fungal Proteins/genetics
SCR Organism:
Nectria haematococca; Fusarium haematococcum
Czasopismo naukowe
Tytuł:
Tuning transcription factor DegU for developing extracellular protease overproducer in Bacillus pumilus.
Autorzy:
Xie CY; Key Laboratory for Bio-resources and Eco-Environment of the Ministry of Education, Sichuan Key Laboratory of Molecular Biology and Biotechnology, College of Life Sciences, Sichuan University, Chengdu, 610064, People's Republic of China.
Li WJ; Key Laboratory for Bio-resources and Eco-Environment of the Ministry of Education, Sichuan Key Laboratory of Molecular Biology and Biotechnology, College of Life Sciences, Sichuan University, Chengdu, 610064, People's Republic of China.
Feng H; Key Laboratory for Bio-resources and Eco-Environment of the Ministry of Education, Sichuan Key Laboratory of Molecular Biology and Biotechnology, College of Life Sciences, Sichuan University, Chengdu, 610064, People's Republic of China. .
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Źródło:
Microbial cell factories [Microb Cell Fact] 2023 Aug 27; Vol. 22 (1), pp. 163. Date of Electronic Publication: 2023 Aug 27.
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Hydrolases*/genetics
Bacillus pumilus*/genetics
Transcription Factors/genetics ; Gene Expression Regulation ; Bacillus subtilis
Czasopismo naukowe

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