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Tytuł:
Internal Fragments Enhance Middle-Down Mass Spectrometry Structural Characterization of Monoclonal Antibodies and Antibody-Drug Conjugates.
Autorzy:
Wei B; Department of Chemistry and Biochemistry, University of California-Los Angeles, Los Angeles, California 90095, United States.
Lantz C; Department of Chemistry and Biochemistry, University of California-Los Angeles, Los Angeles, California 90095, United States.
Ogorzalek Loo RR; Department of Chemistry and Biochemistry, University of California-Los Angeles, Los Angeles, California 90095, United States.; UCLA-DOE Institute, University of California-Los Angeles, Los Angeles, California 90095, United States.; Molecular Biology Institute, University of California-Los Angeles, Los Angeles, California 90095, United States.
Campuzano IDG; Center for Research Acceleration by Digital Innovation, Molecular Analytics, Amgen Research, Thousand Oaks, California 91320, United States.
Loo JA; Department of Chemistry and Biochemistry, University of California-Los Angeles, Los Angeles, California 90095, United States.; Department of Biological Chemistry, University of California-Los Angeles, Los Angeles, California 90095, United States.; UCLA-DOE Institute, University of California-Los Angeles, Los Angeles, California 90095, United States.; Molecular Biology Institute, University of California-Los Angeles, Los Angeles, California 90095, United States.
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Źródło:
Analytical chemistry [Anal Chem] 2024 Feb 13; Vol. 96 (6), pp. 2491-2499. Date of Electronic Publication: 2024 Jan 31.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal*/chemistry
Immunoconjugates*/chemistry
Mass Spectrometry/methods ; Peptide Mapping ; Lysine/chemistry
Czasopismo naukowe
Tytuł:
Qualification of a LC-HRMS platform method for biosimilar development using NISTmab as a model.
Autorzy:
Tank P; Analytical Chemistry Division of Zelle Biotechnology Research and Analytical Services, Zelle Biotechnology Pvt. Ltd., A-7 M.I.D.C., Mira Industrial Area, Western Express Highway, Mira Road, Thane, 401 104, India. Electronic address: .
Vora S; Analytical Chemistry Division of Zelle Biotechnology Research and Analytical Services, Zelle Biotechnology Pvt. Ltd., A-7 M.I.D.C., Mira Industrial Area, Western Express Highway, Mira Road, Thane, 401 104, India. Electronic address: .
Tripathi S; Analytical Chemistry Division of Zelle Biotechnology Research and Analytical Services, Zelle Biotechnology Pvt. Ltd., A-7 M.I.D.C., Mira Industrial Area, Western Express Highway, Mira Road, Thane, 401 104, India. Electronic address: .
D'Souza F; Analytical Chemistry Division of Zelle Biotechnology Research and Analytical Services, Zelle Biotechnology Pvt. Ltd., A-7 M.I.D.C., Mira Industrial Area, Western Express Highway, Mira Road, Thane, 401 104, India. Electronic address: .
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Źródło:
Analytical biochemistry [Anal Biochem] 2024 May; Vol. 688, pp. 115475. Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Biosimilar Pharmaceuticals*/analysis
Biosimilar Pharmaceuticals*/chemistry
Antibodies, Monoclonal/chemistry ; Liquid Chromatography-Mass Spectrometry ; Peptide Mapping/methods ; Peptides
Czasopismo naukowe
Tytuł:
Exploring the Release of Elastin Peptides Generated from Enzymatic Hydrolysis of Bovine Elastin via Peptide Mapping.
Autorzy:
Zhang J; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.; Guangdong Food Green Processing and Nutrition Regulation Technologies Research Center, Guangzhou 510650, China.
Liu Y; College of Food Science and Technology, Hunan Agricultural University, Changsha 410125, China.
Jiang L; College of Food Science and Technology, Hunan Agricultural University, Changsha 410125, China.
Zhao T; Sericulture & Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences, Key Laboratory of Functional Foods, Ministry of Agriculture and Rural Affairs, Guangdong Key Laboratory of Agricultural Products Processing, Guangzhou 510610, China.
Su G; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.; Guangdong Food Green Processing and Nutrition Regulation Technologies Research Center, Guangzhou 510650, China.
Zhao M; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.; Guangdong Food Green Processing and Nutrition Regulation Technologies Research Center, Guangzhou 510650, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Nov 10; Vol. 28 (22). Date of Electronic Publication: 2023 Nov 10.
Typ publikacji:
Journal Article
MeSH Terms:
Elastin*/chemistry
Peptides*/chemistry
Animals ; Cattle ; Hydrolysis ; Peptide Mapping ; Pancreatic Elastase ; Protein Hydrolysates
Czasopismo naukowe
Tytuł:
Fully Unattended Online Protein Digestion and LC-MS Peptide Mapping.
Autorzy:
Richardson J; Process Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States.
Zhang Z; Process Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States.
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Źródło:
Analytical chemistry [Anal Chem] 2023 Oct 24; Vol. 95 (42), pp. 15514-15521. Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
Tandem Mass Spectrometry*/methods
Peptide Hydrolases*
Chromatography, Liquid/methods ; Peptide Mapping/methods ; Proteolysis ; Chromatography, High Pressure Liquid/methods
Czasopismo naukowe
Tytuł:
AmorProt: Amino Acid Molecular Fingerprints Repurposing-Based Protein Fingerprint.
Autorzy:
Lee M; School of Systems Biomedical Science, Soongsil University, 369 Sangdo-ro, Dongjak-gu, Seoul 06978, Republic of Korea.
Min K; School of Mechanical Engineering, Soongsil University, 369 Sangdo-ro, Dongjak-gu, Seoul 06978, Republic of Korea.
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Źródło:
Biochemistry [Biochemistry] 2023 Sep 19; Vol. 62 (18), pp. 2700-2709. Date of Electronic Publication: 2023 Aug 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Artificial Intelligence*
Algorithms*
Peptide Mapping ; Amino Acids ; Amyloidogenic Proteins
Czasopismo naukowe
Tytuł:
Assessment of structural and functional similarity of biosimilar products: Bevacizumab as a case study.
Autorzy:
Bhattacharya S; Chemical Engineering Department, Indian Institute of Technology, Delhi, India.
Rathore AS; Chemical Engineering Department, Indian Institute of Technology, Delhi, India. Electronic address: .
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Źródło:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2023 Sep 01; Vol. 1229, pp. 123896. Date of Electronic Publication: 2023 Sep 25.
Typ publikacji:
Journal Article
MeSH Terms:
Biosimilar Pharmaceuticals*/analysis
Bevacizumab ; Protein Processing, Post-Translational ; Angiogenesis Inhibitors ; Peptide Mapping/methods
Czasopismo naukowe
Tytuł:
Method for detecting rare differences between two LC-MS runs.
Autorzy:
Zhang Z; Process Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA, 91320, USA. Electronic address: .
Richardson J; Process Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA, 91320, USA.
Shah B; Process Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA, 91320, USA.
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Źródło:
Analytical biochemistry [Anal Biochem] 2023 Aug 01; Vol. 674, pp. 115211. Date of Electronic Publication: 2023 Jun 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tandem Mass Spectrometry*
Chromatography, Liquid/methods ; Peptide Mapping/methods
Czasopismo naukowe
Tytuł:
Protein identification by nanopore peptide profiling.
Autorzy:
Lucas FLR; Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, Netherlands.
Versloot RCA; Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, Netherlands.
Yakovlieva L; Stratingh Institute for Chemistry, University of Groningen, Groningen, Netherlands.
Walvoort MTC; Stratingh Institute for Chemistry, University of Groningen, Groningen, Netherlands.
Maglia G; Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, Netherlands. .
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Źródło:
Nature communications [Nat Commun] 2021 Oct 04; Vol. 12 (1), pp. 5795. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nanopores*
Peptide Mapping/*methods
Proteins/*chemistry
Calibration ; Cnidarian Venoms/chemistry ; Hydrolysis ; Muramidase/chemistry ; Muramidase/metabolism ; Peptide Mapping/standards ; Peptides/analysis ; Proteins/metabolism
Czasopismo naukowe
Tytuł:
Peptide Location Fingerprinting Reveals Tissue Region-Specific Differences in Protein Structures in an Ageing Human Organ.
Autorzy:
Eckersley A; Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Manchester M13 9PT, UK.
Ozols M; Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Manchester M13 9PT, UK.; Department of Human Genetics, Wellcome Sanger Institute, Genome Campus, Hinxton CB10 1SA, UK.
Chen P; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.; Department of Orthopaedics and Traumatology, The University of Hong Kong-Shenzhen Hospital (HKU-SZH), Shenzhen 518053, China.
Tam V; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
Hoyland JA; Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Manchester M13 9PT, UK.; NIHR Manchester Biomedical Research Centre, Central Manchester Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9PL, UK.
Trafford A; Manchester Academic Health Science Centre, Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, UK.
Chan D; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
Sherratt MJ; Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Manchester M13 9PT, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 27; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 27.
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Mapping*
Aging/*metabolism
Collagen/*metabolism
Intervertebral Disc/*metabolism
Aged ; Extracellular Matrix ; Humans ; Proteomics
Czasopismo naukowe
Tytuł:
Oligonucleotide mapping via mass spectrometry to enable comprehensive primary structure characterization of an mRNA vaccine against SARS-CoV-2.
Autorzy:
Gau BC; BioTherapeutics Pharmaceutical Sciences, Pfizer Inc, Chesterfield, MO, USA. .
Dawdy AW; BioTherapeutics Pharmaceutical Sciences, Pfizer Inc, Chesterfield, MO, USA. .
Wang HL; BioTherapeutics Pharmaceutical Sciences, Pfizer Inc, Chesterfield, MO, USA.
Bare B; BioTherapeutics Pharmaceutical Sciences, Pfizer Inc, Chesterfield, MO, USA.
Castaneda CH; BioTherapeutics Pharmaceutical Sciences, Pfizer Inc, Chesterfield, MO, USA.
Friese OV; BioTherapeutics Pharmaceutical Sciences, Pfizer Inc, Chesterfield, MO, USA.
Thompson MS; BioTherapeutics Pharmaceutical Sciences, Pfizer Inc, Andover, MA, USA.
Lerch TF; BioTherapeutics Pharmaceutical Sciences, Pfizer Inc, Chesterfield, MO, USA.
Cirelli DJ; BioTherapeutics Pharmaceutical Sciences, Pfizer Inc, Andover, MA, USA.
Rouse JC; BioTherapeutics Pharmaceutical Sciences, Pfizer Inc, Andover, MA, USA.
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Źródło:
Scientific reports [Sci Rep] 2023 Jun 03; Vol. 13 (1), pp. 9038. Date of Electronic Publication: 2023 Jun 03.
Typ publikacji:
Journal Article
MeSH Terms:
Tandem Mass Spectrometry*/methods
COVID-19*/prevention & control
Humans ; Chromatography, Liquid/methods ; SARS-CoV-2/genetics ; COVID-19 Vaccines ; Oligonucleotides/genetics ; mRNA Vaccines ; Peptide Mapping/methods ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł:
Interlaboratory Evaluation of a User-Friendly Benchtop Mass Spectrometer for Multiple-Attribute Monitoring Studies of a Monoclonal Antibody.
Autorzy:
Butré CI; Quality Assistance sa, Technoparc de Thudinie 2, 6536 Thuin, Belgium.
D'Atri V; School of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel Servet 1, 1211 Geneva, Switzerland.; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU-Rue Michel Servet 1, 1211 Geneva, Switzerland.
Diemer H; Laboratoire de Spectrométrie de Masse BioOrganique, Université de Strasbourg, CNRS, IPHC UMR 7178, 67000 Strasbourg, France.; Infrastructure Nationale de Protéomique ProFI-FR2048, 67087 Strasbourg, France.
Colas O; Biologics CMC and Developability, IRPF, Centre d'Immunologie Pierre Fabre, 5 Avenue Napoleon III, 74160 Saint-Julien en Genevois, France.
Wagner E; Biologics CMC and Developability, IRPF, Centre d'Immunologie Pierre Fabre, 5 Avenue Napoleon III, 74160 Saint-Julien en Genevois, France.
Beck A; Biologics CMC and Developability, IRPF, Centre d'Immunologie Pierre Fabre, 5 Avenue Napoleon III, 74160 Saint-Julien en Genevois, France.
Cianferani S; Laboratoire de Spectrométrie de Masse BioOrganique, Université de Strasbourg, CNRS, IPHC UMR 7178, 67000 Strasbourg, France.; Infrastructure Nationale de Protéomique ProFI-FR2048, 67087 Strasbourg, France.
Guillarme D; School of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel Servet 1, 1211 Geneva, Switzerland.; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU-Rue Michel Servet 1, 1211 Geneva, Switzerland.
Delobel A; Quality Assistance sa, Technoparc de Thudinie 2, 6536 Thuin, Belgium.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Mar 22; Vol. 28 (6). Date of Electronic Publication: 2023 Mar 22.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Monoclonal*/chemistry
Mass Spectrometry/methods ; Chromatography, Liquid/methods ; Glycosylation ; Peptide Mapping/methods
Czasopismo naukowe
Tytuł:
Cutting-edge mass spectrometry strategy based on imaged capillary isoelectric focusing (icIEF) technology for characterizing charge heterogeneity of monoclonal antibody.
Autorzy:
Zhang X; Thermo Fisher Scientific, Shanghai, China.
Chen T; Advanced Electrophoresis Solution Ltd., Cambridge, Canada. Electronic address: .
Li V; Advanced Electrophoresis Solution Ltd., Cambridge, Canada.
Bo T; Advanced Electrophoresis Solution Ltd., Cambridge, Canada.
Du M; Themo Fisher Scientific, Massachusetts, USA. Electronic address: .
Huang T; Advanced Electrophoresis Solution Ltd., Cambridge, Canada.
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Źródło:
Analytical biochemistry [Anal Biochem] 2023 Jan 01; Vol. 660, pp. 114961. Date of Electronic Publication: 2022 Oct 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal*
Biological Products*
Isoelectric Focusing ; Mass Spectrometry ; Peptide Mapping ; Quality Control
Czasopismo naukowe
Tytuł:
Immunoreactive peptide maps of SARS-CoV-2.
Autorzy:
Mishra N; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA. .
Huang X; Sun Yat-sen University, Guangzhou, Guangdong Province, China.; Center for Infection and Immunity, Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China.
Joshi S; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
Guo C; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
Ng J; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
Thakkar R; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
Wu Y; Sun Yat-sen University, Guangzhou, Guangdong Province, China.; Center for Infection and Immunity, Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China.
Dong X; Sun Yat-sen University, Guangzhou, Guangdong Province, China.; Center for Infection and Immunity, Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China.
Li Q; Sun Yat-sen University, Guangzhou, Guangdong Province, China.; School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, China.
Pinapati RS; Nimble Therapeutics Inc, Madison, WI, USA.
Sullivan E; Nimble Therapeutics Inc, Madison, WI, USA.
Caciula A; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
Tokarz R; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
Briese T; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
Lu J; Sun Yat-sen University, Guangzhou, Guangdong Province, China. .; School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, China. .
Lipkin WI; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA. .
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Źródło:
Communications biology [Commun Biol] 2021 Feb 12; Vol. 4 (1), pp. 225. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptide Mapping*
COVID-19/*immunology
COVID-19/*virology
Peptides/*immunology
SARS-CoV-2/*physiology
Amino Acid Sequence ; Animals ; COVID-19/blood ; Chiroptera ; Epitopes/immunology ; Humans ; Immunoglobulin G/metabolism ; Peptides/chemistry ; Proteome/metabolism
Czasopismo naukowe
Tytuł:
Monomer structure fingerprints: an extension of the monomer composition version for peptide databases.
Autorzy:
Abdo A; Univ. Lille, CNRS, Centrale Lille, UMR 9189 - CRIStAL - Centre de Recherche en Informatique Signal et Automatique de Lille, 59000, Lille, France. ammar_.; Computer Science Department, Hodeidah University, Hodeidah, Yemen. ammar_.
Ghaleb E; Computer Science Department, Aden Community College, Aden, Yemen.
Alajmi NKA; Saad Al-Abdullah Academy for Security Sciences, Al Kuwait, Kuwait.
Pupin M; Univ. Lille, CNRS, Centrale Lille, UMR 9189 - CRIStAL - Centre de Recherche en Informatique Signal et Automatique de Lille, 59000, Lille, France.
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Źródło:
Journal of computer-aided molecular design [J Comput Aided Mol Des] 2020 Nov; Vol. 34 (11), pp. 1147-1156. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptide Mapping*
Peptides/*chemistry
Amino Acid Sequence ; Databases, Protein ; Models, Molecular ; Protein Conformation ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Development, validation, and implementation of a robust and quality control-friendly focused peptide mapping method for monitoring oxidation of co-formulated monoclonal antibodies.
Autorzy:
Xu C; Merck & Co., Inc., Kenilworth, NJ, 07033-1310, USA. .
Khanal S; Merck & Co., Inc., Kenilworth, NJ, 07033-1310, USA.
Pierson NA; Merck & Co., Inc., Kenilworth, NJ, 07033-1310, USA.
Quiroz J; Merck & Co., Inc., Kenilworth, NJ, 07033-1310, USA.
Kochert B; Merck & Co., Inc., Kenilworth, NJ, 07033-1310, USA.
Yang X; Merck & Co., Inc., Kenilworth, NJ, 07033-1310, USA.
Wylie D; Merck & Co., Inc., Kenilworth, NJ, 07033-1310, USA.
Strulson CA; Merck & Co., Inc., Kenilworth, NJ, 07033-1310, USA.
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2022 Dec; Vol. 414 (29-30), pp. 8317-8330. Date of Electronic Publication: 2022 Nov 29.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Monoclonal*
Antineoplastic Agents, Immunological*
Humans ; Peptide Mapping ; Quality Control ; Oxidation-Reduction
Czasopismo naukowe
Tytuł:
Multi-Attribute Monitoring of Complex Erythropoetin Beta Glycosylation by GluC Liquid Chromatography-Mass Spectrometry Peptide Mapping.
Autorzy:
Buettner A; Pharma Technical Development, Roche Diagnostics GmbH, Penzberg 82377, Germany.
Maier M; Pharma Technical Development, Roche Diagnostics GmbH, Penzberg 82377, Germany.
Bonnington L; Pharma Technical Development, Roche Diagnostics GmbH, Penzberg 82377, Germany.
Bulau P; Pharma Technical Development, Roche Diagnostics GmbH, Penzberg 82377, Germany.
Reusch D; Pharma Technical Development, Roche Diagnostics GmbH, Penzberg 82377, Germany.
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Źródło:
Analytical chemistry [Anal Chem] 2020 Jun 02; Vol. 92 (11), pp. 7574-7580. Date of Electronic Publication: 2020 May 19.
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Mapping*
Erythropoietin/*analysis
Serine Endopeptidases/*metabolism
Chromatography, Liquid ; Erythropoietin/metabolism ; Glycosylation ; Humans ; Mass Spectrometry ; Recombinant Proteins/analysis ; Recombinant Proteins/metabolism
Czasopismo naukowe
Tytuł:
Are 2D fingerprints still valuable for drug discovery?
Autorzy:
Gao K; Department of Mathematics, Michigan State University, MI 48824, USA. .
Nguyen DD; Department of Mathematics, Michigan State University, MI 48824, USA. .
Sresht V; Pfizer Medicine Design, 610 Main St, Cambridge, MA 02139, USA.
Mathiowetz AM; Pfizer Medicine Design, 610 Main St, Cambridge, MA 02139, USA.
Tu M; Pfizer Medicine Design, 610 Main St, Cambridge, MA 02139, USA.
Wei GW; Department of Mathematics, Michigan State University, MI 48824, USA. and Department of Electrical and Computer Engineering, Michigan State University, MI 48824, USA and Department of Biochemistry and Molecular Biology, Michigan State University, MI 48824, USA.
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Źródło:
Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2020 Apr 29; Vol. 22 (16), pp. 8373-8390.
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Mapping*
Chemistry Techniques, Analytical/*standards
Drug Discovery/*methods
Algorithms ; Datasets as Topic
Czasopismo naukowe
Tytuł:
Native peptide mapping - A simple method to routinely monitor higher order structure changes and relation to functional activity.
Autorzy:
Degueldre M; Department of Analytical Science Biologicals, UCB , Braine L'Alleud , Belgium.
Wielant A; Department of Analytical Science Biologicals, UCB , Braine L'Alleud , Belgium.
Girot E; Department of Analytical Science Biologicals, UCB , Braine L'Alleud , Belgium.
Burkitt W; Department of Analytical Science Biologicals, UCB , Slough , UK.
O'Hara J; Department of Analytical Science Biologicals, UCB , Slough , UK.
Debauve G; Department of Analytical Science Biologicals, UCB , Braine L'Alleud , Belgium.
Gervais A; Department of Analytical Science Biologicals, UCB , Braine L'Alleud , Belgium.
Jone C; Department of Analytical Science Biologicals, UCB , Braine L'Alleud , Belgium.
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Źródło:
MAbs [MAbs] 2019 Nov-Dec; Vol. 11 (8), pp. 1391-1401. Date of Electronic Publication: 2019 Oct 04.
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Mapping*
Antibodies, Monoclonal/*chemistry
Immunoglobulin G/*chemistry
Animals ; Dogs ; Humans ; Madin Darby Canine Kidney Cells
Czasopismo naukowe
Tytuł:
Dual Biomimetic Recognition-Driven Plasmonic Nanogap-Enhanced Raman Scattering for Ultrasensitive Protein Fingerprinting and Quantitation.
Autorzy:
He H; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Nanjing 210023, China.
Zhou L; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Nanjing 210023, China.
Guo Z; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Nanjing 210023, China.
Li P; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Nanjing 210023, China.
Gao S; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Nanjing 210023, China.
Liu Z; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Nanjing 210023, China.
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Źródło:
Nano letters [Nano Lett] 2022 Dec 14; Vol. 22 (23), pp. 9664-9671. Date of Electronic Publication: 2022 Nov 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Molecular Imprinting*
Metal Nanoparticles*
Spectrum Analysis, Raman ; Gold ; Biomimetics ; Peptide Mapping ; Proteins
Czasopismo naukowe
Tytuł:
Optimized Multi-Attribute Method Workflow Addressing Missed Cleavages and Chromatographic Tailing/Carry-Over of Hydrophobic Peptides.
Autorzy:
Kristensen DB; Symphogen, Pederstrupvej 93, 2750 Ballerup, Denmark.
Ørgaard M; Symphogen, Pederstrupvej 93, 2750 Ballerup, Denmark.
Sloth TM; Symphogen, Pederstrupvej 93, 2750 Ballerup, Denmark.
Christoffersen NS; Symphogen, Pederstrupvej 93, 2750 Ballerup, Denmark.
Leth-Espensen KZ; Symphogen, Pederstrupvej 93, 2750 Ballerup, Denmark.
Jensen PF; Symphogen, Pederstrupvej 93, 2750 Ballerup, Denmark.
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Źródło:
Analytical chemistry [Anal Chem] 2022 Dec 13; Vol. 94 (49), pp. 17195-17204. Date of Electronic Publication: 2022 Nov 08.
Typ publikacji:
Journal Article
MeSH Terms:
Tandem Mass Spectrometry*/methods
Peptides*/chemistry
Reproducibility of Results ; Chromatography, Liquid/methods ; Peptide Mapping/methods ; Workflow
Czasopismo naukowe

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