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Wyszukujesz frazę ""Peptides"" wg kryterium: Temat


Tytuł :
Antimicrobial Peptides: Vestiges of Past or Modern Therapeutics?
Autorzy :
Mitra JB; Radiopharmaceuticals Division, Anushaktinagar, Mumbai- 400094, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai- 400094, India.
Sharma VK; Homi Bhabha National Institute, Anushaktinagar, Mumbai- 400094, India.; Solid State Physics Division, Anushaktinagar, Mumbai- 400094, India.
Kumar M; Homi Bhabha National Institute, Anushaktinagar, Mumbai- 400094, India.; Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre (BARC), Mumbai 400085, India.
Mukherjee A; Radiopharmaceuticals Division, Anushaktinagar, Mumbai- 400094, India.; Homi Bhabha National Institute, Anushaktinagar, Mumbai- 400094, India.
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Źródło :
Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2020; Vol. 20 (3), pp. 183-195.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antimicrobial Cationic Peptides*/chemistry
Antimicrobial Cationic Peptides*/immunology
Antimicrobial Cationic Peptides*/pharmacology
Drug Discovery*
Anti-Infective Agents/*pharmacology
Drug Resistance, Multiple/*drug effects
Oligopeptides/*pharmacology
Peptides, Cyclic/*pharmacology
Amino Acid Sequence ; Animals ; Anti-Infective Agents/administration & dosage ; Anti-Infective Agents/chemistry ; Communicable Diseases/diagnosis ; Communicable Diseases/drug therapy ; Communicable Diseases/microbiology ; Evolution, Molecular ; Humans ; Oligopeptides/chemistry ; Oligopeptides/immunology ; Peptides, Cyclic/chemistry ; Peptides, Cyclic/immunology ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Design and validation of a frugal, automated, solid-phase peptide synthesizer.
Autorzy :
Kallmyer NE; Department of Chemical and Biological Engineering, Iowa State University, Ames, Iowa, United States of America.
Rider NE; Department of Chemical and Biological Engineering, Iowa State University, Ames, Iowa, United States of America.
Reuel NF; Department of Chemical and Biological Engineering, Iowa State University, Ames, Iowa, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Aug 19; Vol. 15 (8), pp. e0237473. Date of Electronic Publication: 2020 Aug 19 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Peptides/*chemical synthesis
Solid-Phase Synthesis Techniques/*methods
Amino Acid Sequence ; Automation ; Cell-Penetrating Peptides/chemical synthesis ; Cell-Penetrating Peptides/chemistry ; Equipment Design ; Fluorometry ; Nanostructures/chemistry ; Oxidation-Reduction ; Peptides/chemistry ; Solid-Phase Synthesis Techniques/economics ; Solid-Phase Synthesis Techniques/instrumentation
Czasopismo naukowe
Tytuł :
Membrane pore-formation correlates with the hydrophilic angle of histidine-rich amphipathic peptides with multiple biological activities.
Autorzy :
Lointier M; Université de Strasbourg/CNRS, UMR7177, Institut de Chimie, 4, Rue Blaise Pascal, 67070 Strasbourg, France.
Aisenbrey C; Université de Strasbourg/CNRS, UMR7177, Institut de Chimie, 4, Rue Blaise Pascal, 67070 Strasbourg, France.
Marquette A; Université de Strasbourg/CNRS, UMR7177, Institut de Chimie, 4, Rue Blaise Pascal, 67070 Strasbourg, France.
Tan JH; Université de Strasbourg/CNRS, UMR7177, Institut de Chimie, 4, Rue Blaise Pascal, 67070 Strasbourg, France.
Kichler A; Université de Strasbourg/CNRS, UMR7199, Laboratoire de Conception et Application de Molécules Bioactives, Faculté de Pharmacie, 67401 Illkirch, France.
Bechinger B; Université de Strasbourg/CNRS, UMR7177, Institut de Chimie, 4, Rue Blaise Pascal, 67070 Strasbourg, France; Institut Universitaire de France. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2020 Aug 01; Vol. 1862 (8), pp. 183212. Date of Electronic Publication: 2020 Feb 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimicrobial Cationic Peptides/*pharmacology
DNA/*genetics
Histidine/*genetics
Membranes/*drug effects
Alanine/genetics ; Antimicrobial Cationic Peptides/chemistry ; Antimicrobial Cationic Peptides/genetics ; Cell Line, Tumor ; Cell-Penetrating Peptides/chemistry ; Cell-Penetrating Peptides/genetics ; Cell-Penetrating Peptides/pharmacology ; DNA/drug effects ; Humans ; Hydrophobic and Hydrophilic Interactions/drug effects ; Lentivirus/genetics ; Leucine/genetics ; Membranes/metabolism ; Porosity ; Transfection
Czasopismo naukowe
Tytuł :
Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Autorzy :
Wells JN; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Buschauer R; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Mackens-Kiani T; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Best K; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Kratzat H; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Berninghausen O; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Becker T; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Gilbert W; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America.
Cheng J; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
Beckmann R; Gene Center and Center for Integrated Protein Science Munich, Department of Biochemistry, University of Munich, Munich, Germany.
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Źródło :
PLoS biology [PLoS Biol] 2020 Jul 20; Vol. 18 (7), pp. e3000780. Date of Electronic Publication: 2020 Jul 20 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Cycle Proteins/*chemistry
Cell Cycle Proteins/*metabolism
Intracellular Signaling Peptides and Proteins/*chemistry
Intracellular Signaling Peptides and Proteins/*metabolism
Ribosomal Proteins/*chemistry
Ribosomal Proteins/*metabolism
Ribosomes/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*chemistry
Saccharomyces cerevisiae Proteins/*metabolism
Adaptor Proteins, Signal Transducing/metabolism ; Amino Acid Sequence ; Binding Sites ; Conserved Sequence ; Evolution, Molecular ; HEK293 Cells ; Humans ; Models, Molecular ; Peptides/chemistry ; Protein Binding ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Transfer/metabolism ; RNA-Binding Proteins/metabolism ; Ribosomes/ultrastructure ; Saccharomyces cerevisiae/ultrastructure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Insights into the mechanism of action of two analogues of aurein 2.2.
Autorzy :
Raheem N; Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada.
Kumar P; Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada.
Lee E; Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada.
Cheng JTJ; Centre for Microbial Diseases and Immunity Research, Department of Microbiology and Immunology, University of British Columbia, 2259 Lower Mall Research Station, Vancouver, British Columbia V6T 1Z4, Canada.
Hancock REW; Centre for Microbial Diseases and Immunity Research, Department of Microbiology and Immunology, University of British Columbia, 2259 Lower Mall Research Station, Vancouver, British Columbia V6T 1Z4, Canada.
Straus SK; Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2020 Jun 01; Vol. 1862 (6), pp. 183262. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimicrobial Cationic Peptides/*chemistry
Amphibian Proteins/chemistry ; Amphibians ; Animals ; Antimicrobial Cationic Peptides/pharmacology ; Cell-Penetrating Peptides/chemistry ; Drug Discovery ; Gram-Positive Bacteria/drug effects ; Protein Conformation ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Antimicrobial peptide (AMP) from Zingiber zerumbet rhizomes with inhibitory effect on Pythium myriotylum secretory proteases and zoospore viability.
Autorzy :
Raj S; School of Biotechnology, National Institute of Technology Calicut, Calicut, 673 601, India.
Aswati Nair R; Department of Biochemistry and Molecular Biology, Central University of Kerala (CUK), Kasaragod, 671 320, India. .
Peter P; School of Biotechnology, National Institute of Technology Calicut, Calicut, 673 601, India.
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Źródło :
World journal of microbiology & biotechnology [World J Microbiol Biotechnol] 2020 May 13; Vol. 36 (5), pp. 77. Date of Electronic Publication: 2020 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Antimicrobial Cationic Peptides/*pharmacology
Peptide Hydrolases/*drug effects
Plant Extracts/*pharmacology
Pythium/*drug effects
Rhizome/*microbiology
Zingiberaceae/*microbiology
Anti-Bacterial Agents/chemistry ; Antimicrobial Cationic Peptides/chemistry ; Arabidopsis ; Enzyme Inhibitors ; Fungi/drug effects ; Oryza ; Peptides/pharmacology ; Plant Extracts/chemistry ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Zingiberaceae/growth & development
Czasopismo naukowe
Tytuł :
Purification and identification of novel antioxidant peptides from watermelon seed protein hydrolysates and their cytoprotective effects on H 2 O 2 -induced oxidative stress.
Autorzy :
Wen C; School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China. Electronic address: .
Zhang J; School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China. Electronic address: .
Feng Y; School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Duan Y; School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China; Institute of Food Physical Processing, Jiangsu University, Zhenjiang 212013, China. Electronic address: .
Ma H; School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China; Institute of Food Physical Processing, Jiangsu University, Zhenjiang 212013, China. Electronic address: .
Zhang H; School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2020 Oct 15; Vol. 327, pp. 127059. Date of Electronic Publication: 2020 May 15.
Typ publikacji :
Journal Article
MeSH Terms :
Citrullus/*chemistry
Hydrogen Peroxide/*pharmacology
Oxidative Stress/*drug effects
Peptides/*chemistry
Protein Hydrolysates/*chemistry
Amino Acid Sequence ; Antioxidants/chemistry ; Antioxidants/isolation & purification ; Antioxidants/pharmacology ; Chromatography, High Pressure Liquid ; Citrullus/metabolism ; Hep G2 Cells ; Humans ; Oxidation-Reduction ; Peptides/isolation & purification ; Peptides/pharmacology ; Plant Proteins/metabolism ; Protective Agents/chemistry ; Protective Agents/isolation & purification ; Protective Agents/pharmacology ; Reactive Oxygen Species/metabolism ; Seeds/chemistry ; Seeds/metabolism ; Structure-Activity Relationship ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Effect of analogues of cationic peptides on dentin mineralization markers in odontoblast-like cells.
Autorzy :
Caiaffa KS; Department of Endodontics, Araçatuba School of Dentistry, State University of São Paulo (UNESP), Araçatuba, São Paulo, Brazil; Department of Pediatric Dentistry and Public Health, Araçatuba Dental School, Univ Estadual Paulista (UNESP), Araçatuba, São Paulo, Brazil.
Basso FG; Department of Physiology and Pathology, Araraquara School of Dentistry, State University of São Paulo (UNESP), Araçatuba, São Paulo, Brazil.
Santos-Filho NA; Department of Biochemistry and Chemical Technology, Institute of Chemistry, State University of São Paulo (UNESP), Araraquara, São Paulo, Brazil; Registro Experimental Campus, São Paulo State University (UNESP), Registro, São Paulo, Brazil.
de Souza-Costa CA; Department of Physiology and Pathology, Araraquara School of Dentistry, State University of São Paulo (UNESP), Araçatuba, São Paulo, Brazil.
Sakai VT; Department of Clinics and Surgery, School of Dentistry, Federal University of Alfenas (UNIFAL), Alfenas, São Paulo, Brazil.
Cilli EM; Registro Experimental Campus, São Paulo State University (UNESP), Registro, São Paulo, Brazil.
Duque C; Department of Pediatric Dentistry and Public Health, Araçatuba Dental School, Univ Estadual Paulista (UNESP), Araçatuba, São Paulo, Brazil. Electronic address: .
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Źródło :
Archives of oral biology [Arch Oral Biol] 2019 Jul; Vol. 103, pp. 19-25. Date of Electronic Publication: 2019 May 10.
Typ publikacji :
Journal Article
MeSH Terms :
Antimicrobial Cationic Peptides*
Cathelicidins*
Dentinogenesis*/genetics
Extracellular Matrix Proteins*/genetics
Odontoblasts*
Peptide Fragments*
Phosphoproteins*/genetics
Sialoglycoproteins*/genetics
beta-Defensins*
Animals ; Cells, Cultured ; Dentin ; Humans ; Mice ; Peptides
Czasopismo naukowe
Tytuł :
Selective anticancer activity of synthetic peptides derived from the host defence peptide tritrpticin.
Autorzy :
Arias M; Biochemistry Research Group, Department of Biological Sciences, University of Calgary, 2500 University Dr. NW, Calgary, AB T2N 1N4, Canada; Biophysics Group, School of Physics, Faculty of Sciences, Universidad Nacional de Colombia - Sede Medellín, Calle 65 No 59A-110, Medellín, Colombia.
Haney EF; Centre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Hilchie AL; Centre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, BC V6T 1Z4, Canada; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS B3H 4R2, Canada; Department of Biology, Acadia University, Wolfville, NS B4P 2R6, Canada.
Corcoran JA; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS B3H 4R2, Canada; Microbiology, Immunology and Infectious Disease Department, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4Z6, Canada.
Hyndman ME; Department of Surgery, Division of Urology, Southern Alberta Institute of Urology, University of Calgary, Calgary, AB T2V 1P9, Canada.
Hancock REW; Centre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Vogel HJ; Biochemistry Research Group, Department of Biological Sciences, University of Calgary, 2500 University Dr. NW, Calgary, AB T2N 1N4, Canada. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2020 Aug 01; Vol. 1862 (8), pp. 183228. Date of Electronic Publication: 2020 Feb 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimicrobial Cationic Peptides/*genetics
Antineoplastic Agents/*pharmacology
Oligopeptides/*genetics
Peptides/*genetics
Animals ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Antimicrobial Cationic Peptides/chemistry ; Antimicrobial Cationic Peptides/pharmacology ; Antineoplastic Agents/chemistry ; Circular Dichroism ; Erythrocytes/drug effects ; Escherichia coli/drug effects ; Hemolysis/drug effects ; Humans ; Leukocytes, Mononuclear/drug effects ; Microbial Sensitivity Tests ; Oligopeptides/chemistry ; Peptides/chemistry ; Peptides/pharmacology ; Swine
Czasopismo naukowe
Tytuł :
Evaluation of main post-translational modifications occurring in naturally generated peptides during the ripening of Spanish dry-cured ham.
Autorzy :
Li C; Instituto de Agroquímica y Tecnología de Alimentos (IATA-CSIC), Avenue Agustín Escardino 7, 46980 Paterna (Valencia), Spain.
Mora L; Instituto de Agroquímica y Tecnología de Alimentos (IATA-CSIC), Avenue Agustín Escardino 7, 46980 Paterna (Valencia), Spain.
Gallego M; Instituto de Agroquímica y Tecnología de Alimentos (IATA-CSIC), Avenue Agustín Escardino 7, 46980 Paterna (Valencia), Spain.
Aristoy MC; Instituto de Agroquímica y Tecnología de Alimentos (IATA-CSIC), Avenue Agustín Escardino 7, 46980 Paterna (Valencia), Spain.
Toldrá F; Instituto de Agroquímica y Tecnología de Alimentos (IATA-CSIC), Avenue Agustín Escardino 7, 46980 Paterna (Valencia), Spain. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2020 Dec 01; Vol. 332, pp. 127388. Date of Electronic Publication: 2020 Jun 23.
Typ publikacji :
Journal Article
MeSH Terms :
Meat Products/*analysis
Myosin Light Chains/*metabolism
Peptides/*analysis
Amino Acids/analysis ; Animals ; Chromatography, High Pressure Liquid ; Dipeptides/analysis ; Lipid Peroxidation ; Myosin Light Chains/chemistry ; Oxidation-Reduction ; Peptides/metabolism ; Principal Component Analysis ; Protein Processing, Post-Translational ; Swine ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Misfolded amyloid-β-42 impairs the endosomal-lysosomal pathway.
Autorzy :
Marshall KE; Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, BN1 9QG, UK.
Vadukul DM; Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, BN1 9QG, UK.
Staras K; Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, BN1 9QG, UK. .
Serpell LC; Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, BN1 9QG, UK. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Dec; Vol. 77 (23), pp. 5031-5043. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Folding*/drug effects
Amyloid beta-Peptides/*chemistry
Amyloid beta-Peptides/*metabolism
Endosomes/*metabolism
Lysosomes/*metabolism
Peptide Fragments/*chemistry
Peptide Fragments/*metabolism
Amyloid beta-Peptides/toxicity ; Animals ; Cells, Cultured ; Dynamins/metabolism ; Endocytosis/drug effects ; Endosomes/ultrastructure ; Hydrogen-Ion Concentration ; Lysosomes/drug effects ; Lysosomes/ultrastructure ; Neurons/drug effects ; Neurons/pathology ; Ovalbumin/metabolism ; Peptide Fragments/toxicity ; Rats
Czasopismo naukowe
Tytuł :
SPA: a peptide antagonist that acts as a cell-penetrating peptide for drug delivery.
Autorzy :
Song J; Institute of Pharmacology, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Huang S; Institute of Biochemistry and Molecular Biology, School of Life Sciences, Lanzhou University, Lanzhou, China.
Zhang Z; Institute of Physiology, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Jia B; Institute of Physiology, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Xie H; Institute of Pharmacology, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Kai M; Institute of Biochemistry and Molecular Biology, School of Life Sciences, Lanzhou University, Lanzhou, China.
Zhang W; Institute of Physiology, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
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Źródło :
Drug delivery [Drug Deliv] 2020 Dec; Vol. 27 (1), pp. 91-99.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Camptothecin/*pharmacology
Cell-Penetrating Peptides/*chemistry
Cell-Penetrating Peptides/*pharmacokinetics
Substance P/*analogs & derivatives
Animals ; Antineoplastic Agents, Phytogenic/administration & dosage ; Antineoplastic Agents, Phytogenic/adverse effects ; CHO Cells ; Camptothecin/administration & dosage ; Camptothecin/adverse effects ; Cell-Penetrating Peptides/administration & dosage ; Cricetulus ; Drug Delivery Systems
Czasopismo naukowe
Tytuł :
A molecular docking study revealed that synthetic peptides induced conformational changes in the structure of SARS-CoV-2 spike glycoprotein, disrupting the interaction with human ACE2 receptor.
Autorzy :
Souza PFN; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil. Electronic address: .
Lopes FES; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil.
Amaral JL; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil.
Freitas CDT; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil.
Oliveira JTA; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil.
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Dec 01; Vol. 164, pp. 66-76. Date of Electronic Publication: 2020 Jul 18.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*pharmacology
Betacoronavirus/*chemistry
Coronavirus Infections/*drug therapy
Peptides/*pharmacology
Peptidyl-Dipeptidase A/*chemistry
Pneumonia, Viral/*drug therapy
Spike Glycoprotein, Coronavirus/*chemistry
Antiviral Agents/chemistry ; Betacoronavirus/drug effects ; Betacoronavirus/metabolism ; Binding Sites/drug effects ; Computational Biology ; Coronavirus Infections/metabolism ; Coronavirus Infections/virology ; Humans ; Molecular Docking Simulation ; Pandemics ; Peptides/chemistry ; Peptidyl-Dipeptidase A/metabolism ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/virology ; Protein Binding/drug effects ; Protein Conformation/drug effects ; Protein Interaction Domains and Motifs/drug effects ; Spike Glycoprotein, Coronavirus/metabolism
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Synthetic anti-endotoxin peptides interfere with Gram-positive and Gram-negative bacteria, their adhesion and biofilm formation on titanium.
Autorzy :
Subh L; Clinic of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Correa W; Division of Biophysics, Research Center Borstel - Leibniz Lung Center, Borstel, Germany.
Pinkvos TJ; Institute for Inorganic Chemistry, Leibniz University of Hannover, Hannover, Germany.
Behrens P; Institute for Inorganic Chemistry, Leibniz University of Hannover, Hannover, Germany.
Brandenburg K; Brandenburg Antiinfektiva GmbH, Borstel, Germany.
Gutsmann T; Division of Biophysics, Research Center Borstel - Leibniz Lung Center, Borstel, Germany.
Stiesch M; Clinic of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Doll K; Clinic of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Winkel A; Clinic of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
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Źródło :
Journal of applied microbiology [J Appl Microbiol] 2020 Nov; Vol. 129 (5), pp. 1272-1286. Date of Electronic Publication: 2020 Jun 19.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Bacteria/*drug effects
Bacterial Adhesion/*drug effects
Biofilms/*drug effects
Peptides/*pharmacology
Titanium/*pharmacology
Bacteria/growth & development ; Biofilms/growth & development ; Cell Line ; Humans ; Peptides/chemistry ; Prostheses and Implants/microbiology ; Prosthesis-Related Infections/microbiology ; Prosthesis-Related Infections/prevention & control ; Titanium/chemistry
Czasopismo naukowe
Tytuł :
Heparin-binding Peptides as Novel Therapies to Stop SARS-CoV-2 Cellular Entry and Infection.
Autorzy :
Tavassoly O; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, Canada (O.T.); Neuroimmunology and Neurovirology Branch, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Maryland (F.S.); and Mount Sinai Institute for Systems Biomedicine, Icahn School of Medicine at Mount Sinai, New York, New York (I.T.) .
Safavi F; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, Canada (O.T.); Neuroimmunology and Neurovirology Branch, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Maryland (F.S.); and Mount Sinai Institute for Systems Biomedicine, Icahn School of Medicine at Mount Sinai, New York, New York (I.T.).
Tavassoly I; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, Canada (O.T.); Neuroimmunology and Neurovirology Branch, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, Maryland (F.S.); and Mount Sinai Institute for Systems Biomedicine, Icahn School of Medicine at Mount Sinai, New York, New York (I.T.) .
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2020 Nov; Vol. 98 (5), pp. 612-619. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antiviral Agents/*metabolism
Betacoronavirus/*physiology
Coronavirus Infections/*drug therapy
Heparan Sulfate Proteoglycans/*metabolism
Peptides/*metabolism
Pneumonia, Viral/*drug therapy
Spike Glycoprotein, Coronavirus/*metabolism
Virus Internalization/*drug effects
Animals ; Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Heparan Sulfate Proteoglycans/chemistry ; Humans ; Pandemics ; Peptides/chemistry ; Peptides/pharmacology ; Peptides/therapeutic use ; Spike Glycoprotein, Coronavirus/chemistry
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Membrane-based preparative methods and bioactivities mapping of tempe-based peptides.
Autorzy :
Sitanggang AB; Department of Food Science and Technology, IPB University, Kampus IPB Darmaga, Bogor 16680, Indonesia; Southeast Asian Food and Agricultural Science and Technology (SEAFAST) Center, IPB University, Kampus IPB Darmaga, Bogor 16680, Indonesia. Electronic address: .
Lesmana M; Department of Food Science and Technology, IPB University, Kampus IPB Darmaga, Bogor 16680, Indonesia.
Budijanto S; Department of Food Science and Technology, IPB University, Kampus IPB Darmaga, Bogor 16680, Indonesia; Southeast Asian Food and Agricultural Science and Technology (SEAFAST) Center, IPB University, Kampus IPB Darmaga, Bogor 16680, Indonesia.
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Źródło :
Food chemistry [Food Chem] 2020 Nov 01; Vol. 329, pp. 127193. Date of Electronic Publication: 2020 Jun 02.
Typ publikacji :
Journal Article
MeSH Terms :
Peptides/*chemistry
Soy Foods/*analysis
Amino Acid Sequence ; Angiotensin-Converting Enzyme Inhibitors/chemistry ; Angiotensin-Converting Enzyme Inhibitors/metabolism ; Antioxidants/chemistry ; Chromatography, High Pressure Liquid ; Databases, Protein ; Electrophoresis, Polyacrylamide Gel ; Fermentation ; Filtration ; Flour/analysis ; Hydrolysis ; Mass Spectrometry ; Papain/metabolism ; Peptides/metabolism ; Peptidyl-Dipeptidase A/chemistry ; Peptidyl-Dipeptidase A/metabolism ; Solubility ; Soybeans/metabolism ; Subtilisins/metabolism
Czasopismo naukowe
Tytuł :
Estimating the Binding of Sars-CoV-2 Peptides to HLA Class I in Human Subpopulations Using Artificial Neural Networks.
Autorzy :
La Porta CAM; Center for Complexity and Biosystems, Department of Environmental Science and Policy, University of Milan, via Celoria 26, Milano 20133, Italy; CNR - Consiglio Nazionale delle Ricerche, Istituto di Biofisica, via Celoria 26, Milano 20133, Italy. Electronic address: .
Zapperi S; Center for Complexity and Biosystems, Department of Physics, University of Milan, via Celoria 16, Milano 20133, Italy; CNR - Consiglio Nazionale delle Ricerche, Istituto di Chimica della Materia Condensata e di Tecnologie per l'Energia, via R. Cozzi 53, Milano 20125, Italy.
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Źródło :
Cell systems [Cell Syst] 2020 Oct 21; Vol. 11 (4), pp. 412-417.e2. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Journal Article
MeSH Terms :
Neural Networks, Computer*
Polymorphism, Genetic*
Betacoronavirus/*immunology
Histocompatibility Antigens Class I/*immunology
Peptides/*immunology
Viral Proteins/*immunology
Haplotypes ; Histocompatibility Antigens Class I/chemistry ; Histocompatibility Antigens Class I/genetics ; Humans ; Peptides/chemistry ; Protein Binding ; Viral Proteins/chemistry
SCR Organism :
severe acute respiratory syndrome coronavirus 2
Czasopismo naukowe
Tytuł :
Atomic Structures of Amyloid-β Oligomers Illuminate a Neurotoxic Mechanism.
Autorzy :
Darling AL; Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
Shorter J; Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: .
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Źródło :
Trends in neurosciences [Trends Neurosci] 2020 Oct; Vol. 43 (10), pp. 740-743. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Comment
MeSH Terms :
Alzheimer Disease*
Amyloid beta-Peptides*/metabolism
Amyloid beta-Peptides*/toxicity
Brain/metabolism ; Humans ; Peptide Fragments
Czasopismo naukowe
Tytuł :
Identification of a dorsal transcription factor (MnDorsal) from Macrobrachium nipponense and its role in innate immunity.
Autorzy :
Huang X; Jiangsu Province Engineering Research Center for Aquatic Animals Breeding and Green Efficient Aquacultural Technology, College of Marine Science and Engineering, Nanjing Normal University, 1 Wenyuan Road, Nanjing, Jiangsu, 210023, China.
Zhang R; Jiangsu Province Engineering Research Center for Aquatic Animals Breeding and Green Efficient Aquacultural Technology, College of Marine Science and Engineering, Nanjing Normal University, 1 Wenyuan Road, Nanjing, Jiangsu, 210023, China.
Dai X; Jiangsu Province Engineering Research Center for Aquatic Animals Breeding and Green Efficient Aquacultural Technology, College of Marine Science and Engineering, Nanjing Normal University, 1 Wenyuan Road, Nanjing, Jiangsu, 210023, China.
Wang K; Jiangsu Province Engineering Research Center for Aquatic Animals Breeding and Green Efficient Aquacultural Technology, College of Marine Science and Engineering, Nanjing Normal University, 1 Wenyuan Road, Nanjing, Jiangsu, 210023, China.
Zhang C; Jiangsu Province Engineering Research Center for Aquatic Animals Breeding and Green Efficient Aquacultural Technology, College of Marine Science and Engineering, Nanjing Normal University, 1 Wenyuan Road, Nanjing, Jiangsu, 210023, China.
Cao X; Jiangsu Province Engineering Research Center for Aquatic Animals Breeding and Green Efficient Aquacultural Technology, College of Marine Science and Engineering, Nanjing Normal University, 1 Wenyuan Road, Nanjing, Jiangsu, 210023, China.
Ren Q; Jiangsu Province Engineering Research Center for Aquatic Animals Breeding and Green Efficient Aquacultural Technology, College of Marine Science and Engineering, Nanjing Normal University, 1 Wenyuan Road, Nanjing, Jiangsu, 210023, China; Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Sciences, Shandong Normal University, Jinan, Shandong, 250014, China; Co-Innovation Center for Marine Bio-Industry Technology of Jiangsu Province, Lianyungang, Jiangsu, 222005, China. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2020 Oct; Vol. 126, pp. 1-7. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimicrobial Cationic Peptides/*genetics
Arthropod Proteins/*metabolism
Immunity, Innate/*genetics
Palaemonidae/*immunology
Transcription Factors/*metabolism
Animals ; Antimicrobial Cationic Peptides/immunology ; Aquaculture ; Arthropod Proteins/genetics ; Gene Expression Regulation/immunology ; Gene Knockdown Techniques ; Palaemonidae/genetics ; Palaemonidae/metabolism ; Palaemonidae/microbiology ; Poly I-C/immunology ; Staphylococcus aureus/immunology ; Transcription Factors/genetics ; Vibrio parahaemolyticus/immunology ; White spot syndrome virus 1/immunology
Czasopismo naukowe

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