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Wyświetlanie 1-20 z 471961
Tytuł:
Effect of tandem repeats of antimicrobial peptide CC34 on production of target proteins and activity of Pichia pastoris.
Autorzy:
Zhao ZH; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Key Laboratory of Feed Resource Efficient Utilization and Nutrition Manipulation in Cold Region of Heilongjiang Province, Daqing, 163319, China.
Zhang CX; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Key Laboratory of Feed Resource Efficient Utilization and Nutrition Manipulation in Cold Region of Heilongjiang Province, Daqing, 163319, China.
Li J; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Key Laboratory of Feed Resource Efficient Utilization and Nutrition Manipulation in Cold Region of Heilongjiang Province, Daqing, 163319, China.
Zhang AZ; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Key Laboratory of Feed Resource Efficient Utilization and Nutrition Manipulation in Cold Region of Heilongjiang Province, Daqing, 163319, China.
Zhao FF; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Key Laboratory of Feed Resource Efficient Utilization and Nutrition Manipulation in Cold Region of Heilongjiang Province, Daqing, 163319, China.
Yu GP; Food Science College of Northeast Agricultural University, Harbin, 150030, China. Electronic address: .
Jiang N; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Key Laboratory of Feed Resource Efficient Utilization and Nutrition Manipulation in Cold Region of Heilongjiang Province, Daqing, 163319, China. Electronic address: .
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Źródło:
Protein expression and purification [Protein Expr Purif] 2023 Dec; Vol. 212, pp. 106342. Date of Electronic Publication: 2023 Aug 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antimicrobial Peptides*/chemistry
Antimicrobial Peptides*/pharmacology
Pichia*/genetics
Pichia*/metabolism
Animals ; Rats ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/metabolism ; Peptides/metabolism ; Recombinant Proteins/genetics ; Recombinant Proteins/pharmacology ; Recombinant Proteins/metabolism ; Tandem Repeat Sequences
SCR Organism:
Komagataella pastoris
Czasopismo naukowe
Szczegóły
Tytuł:
Design methods for antimicrobial peptides with improved performance.
Autorzy:
Mwangi J; Key Laboratory of Bioactive Peptides of Yunnan Province, Engineering Laboratory of Peptides of Chinese Academy of Sciences, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, National Resource Centre for Non-Human Primates, Kunming Primate Research Centre, National Research Facility for Phenotypic & Genetic Analysis of Model Animals (Primate Facility), Sino-African Joint Research Centre, New Cornerstone Science Institute, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650107, China.; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan 650204, China.
Kamau PM; Key Laboratory of Bioactive Peptides of Yunnan Province, Engineering Laboratory of Peptides of Chinese Academy of Sciences, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, National Resource Centre for Non-Human Primates, Kunming Primate Research Centre, National Research Facility for Phenotypic & Genetic Analysis of Model Animals (Primate Facility), Sino-African Joint Research Centre, New Cornerstone Science Institute, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650107, China.; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan 650204, China.
Thuku RC; Key Laboratory of Bioactive Peptides of Yunnan Province, Engineering Laboratory of Peptides of Chinese Academy of Sciences, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, National Resource Centre for Non-Human Primates, Kunming Primate Research Centre, National Research Facility for Phenotypic & Genetic Analysis of Model Animals (Primate Facility), Sino-African Joint Research Centre, New Cornerstone Science Institute, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650107, China.; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan 650204, China.
Lai R; Key Laboratory of Bioactive Peptides of Yunnan Province, Engineering Laboratory of Peptides of Chinese Academy of Sciences, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, National Resource Centre for Non-Human Primates, Kunming Primate Research Centre, National Research Facility for Phenotypic & Genetic Analysis of Model Animals (Primate Facility), Sino-African Joint Research Centre, New Cornerstone Science Institute, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650107, China.; Centre for Evolution and Conservation Biology, Southern Marine Science and Engineering Guangdong Laboratory, Guangzhou, Guangdong 511458, China. E-mail: .
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Źródło:
Zoological research [Zool Res] 2023 Nov 18; Vol. 44 (6), pp. 1095-1114.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antimicrobial Cationic Peptides*/pharmacology
Antimicrobial Cationic Peptides*/chemistry
Anti-Infective Agents*
Animals ; Antimicrobial Peptides ; Artificial Intelligence ; Anti-Bacterial Agents/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Self-Entrapment of Antimicrobial Peptides in Silica Particles for Stable and Effective Antimicrobial Peptide Delivery System.
Autorzy:
Ki MR; Department of Biotechnology and Bioinformatics, Korea University, Sejong-ro 2511, Sejong 30019, Republic of Korea.; Institute of Industrial Technology, Korea University, Sejong-ro 2511, Sejong 30019, Republic of Korea.
Kim SH; Department of Biotechnology and Bioinformatics, Korea University, Sejong-ro 2511, Sejong 30019, Republic of Korea.
Park TI; Department of Biotechnology and Bioinformatics, Korea University, Sejong-ro 2511, Sejong 30019, Republic of Korea.
Pack SP; Department of Biotechnology and Bioinformatics, Korea University, Sejong-ro 2511, Sejong 30019, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 16; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 16.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Infective Agents*/pharmacology
Cell-Penetrating Peptides*/pharmacology
Animals ; Humans ; Antimicrobial Peptides ; Silicon Dioxide/pharmacology ; Peptides/pharmacology ; Bacteria ; Mammals
Czasopismo naukowe
Szczegóły
Tytuł:
A novel genetically-encoded bicyclic peptide inhibitor of human urokinase-type plasminogen activator with better cross-reactivity toward the murine orthologue.
Autorzy:
Mazzocato Y; Department of Molecular Sciences and Nanosystems, Ca' Foscari University of Venice, Via Torino 155, 30172 Venice, Italy.
Perin S; Department of Molecular Sciences and Nanosystems, Ca' Foscari University of Venice, Via Torino 155, 30172 Venice, Italy.
Morales-Sanfrutos J; Proteomics Unit, Spanish National Cancer Research Centre (CNIO), C. de Melchor Fernández Almagro 3, 28029 Madrid, Spain.
Romanyuk Z; Department of Molecular Sciences and Nanosystems, Ca' Foscari University of Venice, Via Torino 155, 30172 Venice, Italy.
Pluda S; Department of Molecular Sciences and Nanosystems, Ca' Foscari University of Venice, Via Torino 155, 30172 Venice, Italy; Fidia Farmaceutici S.p.A., Via Ponte della Fabbrica 3/A, Abano Terme 35031, Italy.
Acquasaliente L; Department of Pharmaceutical and Pharmacological Sciences, School of Medicine, University of Padova, Via Marzolo 5, 35131 Padova, Italy.
Borsato G; Department of Molecular Sciences and Nanosystems, Ca' Foscari University of Venice, Via Torino 155, 30172 Venice, Italy.
De Filippis V; Department of Pharmaceutical and Pharmacological Sciences, School of Medicine, University of Padova, Via Marzolo 5, 35131 Padova, Italy.
Scarso A; Department of Molecular Sciences and Nanosystems, Ca' Foscari University of Venice, Via Torino 155, 30172 Venice, Italy.
Angelini A; Department of Molecular Sciences and Nanosystems, Ca' Foscari University of Venice, Via Torino 155, 30172 Venice, Italy; European Centre for Living Technology (ECLT), Ca' Bottacin, Dorsoduro 3911, Calle Crosera, 30123 Venice, Italy. Electronic address: .
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Źródło:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2023 Nov 15; Vol. 95, pp. 117499. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Urokinase-Type Plasminogen Activator*/chemistry
Peptides*/pharmacology
Peptides*/chemistry
Mice ; Humans ; Animals ; Serine Proteases ; Peptides, Cyclic/pharmacology ; Peptides, Cyclic/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Conjugation of antimicrobial peptides to enhance therapeutic efficacy.
Autorzy:
Selvaraj SP; Molecular and Biological Agricultural Science Program, Taiwan International Graduate Program, Academia Sinica, Taipei, 11529, Taiwan; Graduate Institute of Biotechnology, National Chung Hsing University, Taichung, 402, Taiwan.
Chen JY; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, 23-10 Dahuen Rd, Jiaushi, Ilan, 262, Taiwan; The iEGG and Animal Biotechnology Center and the Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, 402, Taiwan. Electronic address: .
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2023 Nov 05; Vol. 259, pp. 115680. Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antimicrobial Peptides*
Anti-Infective Agents*/pharmacology
Antimicrobial Cationic Peptides/pharmacology ; Antimicrobial Cationic Peptides/chemistry ; Anti-Bacterial Agents/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Conformation Dependent Architectures of Assembled Antimicrobial Peptides with Enhanced Antimicrobial Ability.
Autorzy:
Lan X; Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Engineering Research Center of Ministry of Education of China, Beijing Laboratory of Biomedical Materials, School of Pharmaceutical Science, Capital Medical University, Beijing, 100069, China.; Discipline of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, 999077, China.
Zhong J; Discipline of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, 999077, China.; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Huang R; Discipline of Periodontology, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, 999077, China.
Liu Y; Department of Stomatology, Aviation General Hospital of China Medical University and Beijing Institute of Translational Medicine, Chinese Academy of Science, Beijing, 100012, China.
Ma X; National Center for Veterinary Drug Safety Evaluation, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Li X; Discipline of Periodontology, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, 999077, China.
Zhao D; Beijing Institute of Dental Research, Beijing Stomatological Hospital, Capital Medical University, Beijing, 100069, China.
Qing G; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, China.
Zhang Y; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Liu L; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Wang J; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Ma X; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Luo T; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, China.
Guo W; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, China.
Wang Y; Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Engineering Research Center of Ministry of Education of China, Beijing Laboratory of Biomedical Materials, School of Pharmaceutical Science, Capital Medical University, Beijing, 100069, China.
Li LL; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Su YX; Discipline of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, 999077, China.
Liang XJ; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
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Źródło:
Advanced healthcare materials [Adv Healthc Mater] 2023 Nov; Vol. 12 (29), pp. e2301688. Date of Electronic Publication: 2023 Aug 13.
Typ publikacji:
Journal Article
MeSH Terms:
Antimicrobial Peptides*
Nanofibers*
Antimicrobial Cationic Peptides/pharmacology ; Antimicrobial Cationic Peptides/chemistry ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Oligopeptides
Czasopismo naukowe
Szczegóły
Tytuł:
Antimicrobial peptides as potential therapy for gastrointestinal cancers.
Autorzy:
Yang X; Heping Hospital Attached to Changzhi Medical College, Changzhi, 046000, China.
Hua C; Tangshan Fengnan District Traditional Chinese Medicine Hospital, Tangshan, 063000, China. .
Lin L; Tangshan Hongci Hospital, Tangshan, 063000, China.
Ganting Z; Heping Hospital Attached to Changzhi Medical College, Changzhi, 046000, China.
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Źródło:
Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2023 Nov; Vol. 396 (11), pp. 2831-2841. Date of Electronic Publication: 2023 May 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antimicrobial Cationic Peptides*/pharmacology
Antimicrobial Cationic Peptides*/therapeutic use
Gastrointestinal Neoplasms*/drug therapy
Humans ; Antimicrobial Peptides
Czasopismo naukowe
Szczegóły
Tytuł:
Screening and investigation of a short antimicrobial peptide: AVGAV.
Autorzy:
Cao Y; College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China. .
Kang L; College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China. .
Wang Y; College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China. .
Ren Z; College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China. .
Wu H; College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China. .
Liu X; College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China. .
Cong H; College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China. .; State Key Laboratory of Bio-Fibers and Eco-Textiles, Qingdao University, Qingdao 266071, China.; School of Materials Science and Engineering, Shandong University of Technology, Zibo 255000, China.
Yu B; College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China. .; State Key Laboratory of Bio-Fibers and Eco-Textiles, Qingdao University, Qingdao 266071, China.
Shen Y; College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China. .; Key Laboratory of Biomass Chemical Engineering of Ministry of Education, Center for Bionanoengineering, and Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
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Źródło:
Journal of materials chemistry. B [J Mater Chem B] 2023 Nov 22; Vol. 11 (45), pp. 10941-10955. Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
Antimicrobial Cationic Peptides*/pharmacology
Antimicrobial Cationic Peptides*/chemistry
Bacterial Infections*
Mice ; Animals ; Antimicrobial Peptides ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Wound Healing
Czasopismo naukowe
Szczegóły
Tytuł:
Computational Prediction of Cyclic Peptide Structural Ensembles and Application to the Design of Keap1 Binders.
Autorzy:
Fonseca Lopez F; Department of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.
Miao J; Department of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.
Damjanovic J; Department of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.
Bischof L; Department of Protein Evolution, Max Planck Institute for Biology, 72076 Tübingen, Germany.; Interfaculty Institute of Biochemistry, Tübingen University, 72076 Tübingen, Germany.
Braun MB; Department of Protein Evolution, Max Planck Institute for Biology, 72076 Tübingen, Germany.; Interfaculty Institute of Biochemistry, Tübingen University, 72076 Tübingen, Germany.
Ling Y; Department of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.
Hartmann MD; Department of Protein Evolution, Max Planck Institute for Biology, 72076 Tübingen, Germany.; Interfaculty Institute of Biochemistry, Tübingen University, 72076 Tübingen, Germany.
Lin YS; Department of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.
Kritzer JA; Department of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.
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Źródło:
Journal of chemical information and modeling [J Chem Inf Model] 2023 Nov 13; Vol. 63 (21), pp. 6925-6937. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Peptides, Cyclic*/pharmacology
Peptides, Cyclic*/metabolism
NF-E2-Related Factor 2*/metabolism
Kelch-Like ECH-Associated Protein 1/chemistry ; Kelch-Like ECH-Associated Protein 1/metabolism ; Protein Binding ; Peptides/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Designing the antimicrobial peptide with centrosymmetric and amphipathic characterizations for improving antimicrobial activity.
Autorzy:
Lee PC; Department of Chemistry, Tunghai University, Taichung, Taiwan.
Yen CF; Department of Chemistry, Tunghai University, Taichung, Taiwan.
Lin CC; Department of Chemistry, Tunghai University, Taichung, Taiwan.
Lung FT; Department of Chemistry, Tunghai University, Taichung, Taiwan.
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Źródło:
Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2023 Nov; Vol. 29 (11), pp. e3510. Date of Electronic Publication: 2023 May 15.
Typ publikacji:
Journal Article
MeSH Terms:
Antimicrobial Peptides*
Anti-Infective Agents*/pharmacology
Antimicrobial Cationic Peptides/pharmacology ; Antimicrobial Cationic Peptides/chemistry ; Protein Structure, Secondary ; Bacteria ; Microbial Sensitivity Tests ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.
Autorzy:
Shi YY; Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Dong DR; Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Fan G; Department of Urology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Dai MY; Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Liu M; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
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Źródło:
Frontiers in immunology [Front Immunol] 2023 Oct 02; Vol. 14, pp. 1237964. Date of Electronic Publication: 2023 Oct 02 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptides, Cyclic*/pharmacology
Uterine Cervical Neoplasms*
Female ; Humans ; B7-H1 Antigen/metabolism ; Cell Line, Tumor ; Peptides/pharmacology ; Peptides/chemistry ; Transferases ; Disulfides
Czasopismo naukowe
Szczegóły
Tytuł:
A novel cyclic peptide library immobilized on gel-type beads focusing on rapid construction and characterization for comprehensive drug discovery.
Autorzy:
Sasaki T; HiPep Laboratories, Kyoto, Japan.
Kasama T; HiPep Laboratories, Kyoto, Japan.
Nokihara K; HiPep Laboratories, Kyoto, Japan.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2023 Dec; Vol. 102 (6), pp. 1327-1335. Date of Electronic Publication: 2023 Sep 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptide Library*
Peptides, Cyclic*/chemistry
Tandem Mass Spectrometry ; Peptides/chemistry ; Drug Discovery
Czasopismo naukowe
Szczegóły
Tytuł:
Nucleation and Growth of Amyloid Fibrils.
Autorzy:
Jalali S; Department of Physics, New Jersey Institute of Technology, Newark, New Jersey 07102-1982, United States.
Zhang R; Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey 08544, United States.
Haataja MP; Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey 08544, United States.; Princeton Materials Institute, Princeton University, Princeton, New Jersey 08544, United States.
Dias CL; Department of Physics, New Jersey Institute of Technology, Newark, New Jersey 07102-1982, United States.
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Źródło:
The journal of physical chemistry. B [J Phys Chem B] 2023 Nov 16; Vol. 127 (45), pp. 9759-9770. Date of Electronic Publication: 2023 Nov 07.
Typ publikacji:
Journal Article
MeSH Terms:
Amyloid*/chemistry
Peptides*/chemistry
Solvents ; Protein Conformation, beta-Strand ; Motion ; Amyloid beta-Peptides/chemistry ; Peptide Fragments/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Cyclic Peptide Linker Design and Optimization by Molecular Dynamics Simulations.
Autorzy:
Yu L; Janssen Research & Development, LLC, Spring House, Pennsylvania 19477, United States.
Barros SA; Janssen Research & Development, LLC, Spring House, Pennsylvania 19477, United States.
Sun C; Janssen Research & Development, LLC, Spring House, Pennsylvania 19477, United States.
Somani S; Janssen Research & Development, LLC, Spring House, Pennsylvania 19477, United States.
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Źródło:
Journal of chemical information and modeling [J Chem Inf Model] 2023 Nov 13; Vol. 63 (21), pp. 6863-6876. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:
Journal Article
MeSH Terms:
Molecular Dynamics Simulation*
Peptides, Cyclic*/chemistry
Proprotein Convertase 9 ; Peptides/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Identification and Pharmacological Characterization of a Low-Liability Antinociceptive Bifunctional MOR/DOR Cyclic Peptide.
Autorzy:
Li Y; College of Pharmacy, University of South Carolina, Columbia, SC 29208, USA.
Eans SO; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
Ganno-Sherwood M; Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL 34987, USA.
Eliasof A; College of Pharmacy, University of South Carolina, Columbia, SC 29208, USA.
Houghten RA; Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL 34987, USA.
McLaughlin JP; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Nov 11; Vol. 28 (22). Date of Electronic Publication: 2023 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
Analgesics, Opioid*/pharmacology
Peptides, Cyclic*/pharmacology
Mice ; Animals ; Receptors, Opioid, delta/agonists ; Morphine/pharmacology ; Analgesics/pharmacology ; Analgesics/therapeutic use ; Receptors, Opioid, mu/agonists ; Peptides
Czasopismo naukowe
Szczegóły
Tytuł:
Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation.
Autorzy:
Lemma B; Center for Biomolecular Structure and Organization, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, 20742, USA.
Zhang D; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA.
Vamisetti GB; Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Haifa, 3200008, Israel.
Wentz BG; Center for Biomolecular Structure and Organization, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, 20742, USA.
Suga H; Department of Chemistry, Graduate School of Science, The University of Tokyo, Bunkyo-ku, 7-3-1 Hongo, Bunkyo, Tokyo, 113-0033, Japan.
Brik A; Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Haifa, 3200008, Israel. .
Lubkowski J; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA. .
Fushman D; Center for Biomolecular Structure and Organization, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, 20742, USA. .
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Źródło:
Nature communications [Nat Commun] 2023 Nov 08; Vol. 14 (1), pp. 7212. Date of Electronic Publication: 2023 Nov 08.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Polyubiquitin*
Peptides*
Peptides, Cyclic/pharmacology ; Ubiquitin ; Crystallography, X-Ray
Czasopismo naukowe
Szczegóły
Tytuł:
Targeting nucleic acid phase transitions as a mechanism of action for antimicrobial peptides.
Autorzy:
Sneideris T; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
Erkamp NA; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
Ausserwöger H; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
Saar KL; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
Welsh TJ; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
Qian D; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
Katsuya-Gaviria K; Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, UK.
Johncock MLLY; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
Krainer G; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
Borodavka A; Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, UK. .
Knowles TPJ; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK. .; Cavendish Laboratory, Department of Physics, University of Cambridge, J J Thomson Ave, Cambridge, UK. .
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Źródło:
Nature communications [Nat Commun] 2023 Nov 07; Vol. 14 (1), pp. 7170. Date of Electronic Publication: 2023 Nov 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antimicrobial Cationic Peptides*/chemistry
Anti-Infective Agents*/pharmacology
Antimicrobial Peptides ; Anti-Bacterial Agents/pharmacology ; Bacteria/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Bio-inspired peptide-conjugated liposomes for enhanced planktonic bacteria killing and biofilm eradication.
Autorzy:
Shao H; Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, And with the School of Engineering Medicine, Beihang University, Beijing, 100083, China.
Zhou J; Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, And with the School of Engineering Medicine, Beihang University, Beijing, 100083, China. Electronic address: .
Lin X; Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, And with the School of Engineering Medicine, Beihang University, Beijing, 100083, China.
Zhou Y; Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, And with the School of Engineering Medicine, Beihang University, Beijing, 100083, China.
Xue Y; Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, And with the School of Engineering Medicine, Beihang University, Beijing, 100083, China.
Hong W; Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, And with the School of Engineering Medicine, Beihang University, Beijing, 100083, China.
Lin X; Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, And with the School of Engineering Medicine, Beihang University, Beijing, 100083, China.
Jia X; Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, And with the School of Engineering Medicine, Beihang University, Beijing, 100083, China. Electronic address: .
Fan Y; Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, And with the School of Engineering Medicine, Beihang University, Beijing, 100083, China. Electronic address: .
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Źródło:
Biomaterials [Biomaterials] 2023 Sep; Vol. 300, pp. 122183. Date of Electronic Publication: 2023 Jun 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Infective Agents*/metabolism
Cell-Penetrating Peptides*/pharmacology
Cell-Penetrating Peptides*/metabolism
Liposomes/metabolism ; Plankton ; Cell Membrane/metabolism ; Bacteria ; Antimicrobial Cationic Peptides/pharmacology ; Antimicrobial Cationic Peptides/chemistry ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Biofilms ; Microbial Sensitivity Tests
Czasopismo naukowe
Szczegóły
Tytuł:
Marine Invertebrate Antimicrobial Peptides and Their Potential as Novel Peptide Antibiotics.
Autorzy:
Guryanova SV; M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Medical Institute, Peoples' Friendship University of Russia, 117198 Moscow, Russia.
Balandin SV; M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Belogurova-Ovchinnikova OY; Phystech School of Biological and Medical Physics, Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.
Ovchinnikova TV; M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Phystech School of Biological and Medical Physics, Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.; Department of Biotechnology, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
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Źródło:
Marine drugs [Mar Drugs] 2023 Sep 23; Vol. 21 (10). Date of Electronic Publication: 2023 Sep 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antimicrobial Peptides*
Invertebrates*/chemistry
Animals ; Aquatic Organisms/chemistry ; Peptides/pharmacology ; Peptides/metabolism ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/metabolism ; Bacteria
Czasopismo naukowe
Szczegóły
Tytuł:
Evolution of antimicrobial cysteine-rich peptides in plants.
Autorzy:
Ma H; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, 518124, China.; State Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng, 475004, China.; Shenzhen Research Institute of Henan University, Shenzhen, 518000, China.
Feng Y; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, 518124, China.
Cao Q; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, 518124, China.; State Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng, 475004, China.; Shenzhen Research Institute of Henan University, Shenzhen, 518000, China.
Jia J; Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, 518124, China.; State Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng, 475004, China.; Shenzhen Research Institute of Henan University, Shenzhen, 518000, China.
Ali M; School of Agriculture, Sun Yat-Sen University, Shenzhen, 518107, China.
Shah D; Donald Danforth Plant Science Center, Saint Louis, MI, 63132, USA.
Meyers BC; Donald Danforth Plant Science Center, Saint Louis, MI, 63132, USA.; Division of Plant Science and Technology, University of Missouri, Columbia, MO, 65211, USA.
He H; School of Agriculture, Sun Yat-Sen University, Shenzhen, 518107, China. .
Zhang Y; School of Agriculture, Sun Yat-Sen University, Shenzhen, 518107, China. .
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Źródło:
Plant cell reports [Plant Cell Rep] 2023 Sep; Vol. 42 (9), pp. 1517-1527. Date of Electronic Publication: 2023 Jun 28.
Typ publikacji:
Journal Article
MeSH Terms:
Antimicrobial Peptides*
Anti-Infective Agents*/pharmacology
Cysteine/genetics ; Plants/genetics ; Peptides/genetics ; Peptides/pharmacology ; Evolution, Molecular ; Phylogeny
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 471961

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