Temat: "Peptides" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Molecular Mechanism of STIL Coiled-Coil Domain Oligomerization.
Autorzy:: Shamir M; Institute of Chemistry, The Hebrew University of Jerusalem, Safra Campus Givat Ram, Jerusalem 91904, Israel.
Martin FJO; School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK.
Woolfson DN; School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK.; School of Biochemistry, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.; Bristol BioDesign Institute, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK.
Friedler A; Institute of Chemistry, The Hebrew University of Jerusalem, Safra Campus Givat Ram, Jerusalem 91904, Israel.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Sep 27; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 27.
Typ publikacji:: Journal Article
MeSH Terms:: Intracellular Signaling Peptides and Proteins*/chemistry
Biophysical Phenomena ; Circular Dichroism ; Dimerization ; Peptides/chemistry ; Protein Domains ; Proteins ; Humans

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Skocz do pozycji: 2.

Tytuł:: Expression of RAS and RAB interactor 1 (RIN1) in head and neck tumors at selected hospital in Ghana.
Autorzy:: Osei Saahene R; Department of Microbiology and Immunology, School of Medical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.
Barnes P; Department of Physician Assistant Studies, College of Health and Allied Sciences School of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana.
Yeboah FA; Department of Molecular Medicine, School of Medicine and Dentistry Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Agbo E; Department of Human Anatomy, Histology and Embryology, College of Medicine, Jinggangshan University, Ji'an City, China.
Asante DB; Department of Forensic Sciences, School of Biological Sciences, College of Agricultural and Natural Sciences, University of Cape Coast, Cape Coast, Ghana.
Arhin SK; Department of Physician Assistant Studies, College of Health and Allied Sciences School of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Apr 18; Vol. 19 (4), pp. e0301295. Date of Electronic Publication: 2024 Apr 18 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Intracellular Signaling Peptides and Proteins*/genetics
Head and Neck Neoplasms*/genetics
Humans ; Ghana ; Epithelial Cells ; Real-Time Polymerase Chain Reaction

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Skocz do pozycji: 3.

Tytuł:: Identification and functional activity of Nik related kinase (NRK) in benign hyperplastic prostate.
Autorzy:: He W; Department of Urology, Xijing Hospital of Air Force Medical University, West Changle Road 127, Xi'an, China. .
Tian Z; Department of Hepatobiliary Surgery, Xijing Hospital of Air Force Medical University, Xi'an, China.
Dong B; Department of Orthopedics, Ninth Hospital of Xi'an, Xi'an, China.
Cao Y; Department of Urology, Xijing Hospital of Air Force Medical University, West Changle Road 127, Xi'an, China.
Hu W; Department of Urology, Xijing Hospital of Air Force Medical University, West Changle Road 127, Xi'an, China.
Wu P; Department of Urology, Xijing Hospital of Air Force Medical University, West Changle Road 127, Xi'an, China.
Yu L; Department of Urology, Xijing Hospital of Air Force Medical University, West Changle Road 127, Xi'an, China.
Zhang X; Department of Urology, Zhongnan Hospital of Wuhan University, Donghu Road 169, Wuhan, China. .
Guo S; Department of Physiology and Pathophysiology, Air Force Medical University, West Changle Road 169, Xi'an, China. .; Pokaż więcej
Źródło:: Journal of translational medicine [J Transl Med] 2024 Mar 09; Vol. 22 (1), pp. 255. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:: Journal Article
MeSH Terms:: Prostate*/metabolism
Prostatic Hyperplasia*/genetics
Prostatic Hyperplasia*/metabolism
Prostatic Hyperplasia*/pathology
Protein Serine-Threonine Kinases*
Intracellular Signaling Peptides and Proteins*
Male ; Humans ; Aged ; Hyperplasia/metabolism ; Hyperplasia/pathology ; Fibrosis

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Skocz do pozycji: 4.

Tytuł:: Excess phosphate promotes SARS‑CoV‑2 N protein‑induced NLRP3 inflammasome activation via the SCAP‑SREBP2 signaling pathway.
Autorzy:: Liu MH; Department of Clinical Laboratory, The Affiliated Ganzhou Hospital of Nanchang University, Ganzhou, Jiangxi 341000, P.R. China.
Lin XL; Department of Pathology, Huizhou Third People's Hospital, Guangzhou Medical University, Huizhou, Guangdong 516002, P.R. China.
Xiao LL; Department of Nursing, The Affiliated Ganzhou Hospital of Nanchang University, Ganzhou, Jiangxi 341000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2024 Mar; Vol. 29 (3). Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:: Journal Article
MeSH Terms:: Hyperphosphatemia*
COVID-19*
Membrane Proteins*
Intracellular Signaling Peptides and Proteins*
Humans ; Inflammasomes/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Proprotein Convertase 9/metabolism ; Sterol Regulatory Element Binding Protein 2/genetics ; Sterol Regulatory Element Binding Protein 2/metabolism ; SARS-CoV-2/metabolism ; Phosphates ; Sterol Regulatory Element Binding Protein 1/metabolism ; Signal Transduction ; Inflammation

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Skocz do pozycji: 5.

Tytuł:: Inhibition of PRMT5/MEP50 Arginine Methyltransferase Activity Causes Cancer Vulnerability in NDRG2 Adult T-Cell Leukemia/Lymphoma.
Autorzy:: Ichikawa T; Division of Tumor and Cellular Biochemistry, Department of Medical Sciences, University of Miyazaki, Miyazaki 889-1692, Japan.; Department of Microbiology, Saitama Medical University, 38 Morohongo, Moroyama, Iruma-gun, Saitama 350-0495, Japan.
Suekane A; Trauma and Acute Critical Care Center, Tokyo Medical and Dental University Hospital, Tokyo 113-8510, Japan.
Nakahata S; Division of Tumor and Cellular Biochemistry, Department of Medical Sciences, University of Miyazaki, Miyazaki 889-1692, Japan.; Division of HTLV-1/ATL Carcinogenesis and Therapeutics, Joint Research Center for Human Retrovirus Infection, Kagoshima University, Kagoshima 890-8544, Japan.
Iha H; Division of Pathophysiology, The Research Center for GLOBAL and LOCAL Infectious Diseases (RCGLID), Oita University, Yufu 879-5503, Japan.
Shimoda K; Division of Hematology, Diabetes, and Endocrinology, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan.
Murakami T; Department of Microbiology, Saitama Medical University, 38 Morohongo, Moroyama, Iruma-gun, Saitama 350-0495, Japan.
Morishita K; Division of Tumor and Cellular Biochemistry, Department of Medical Sciences, University of Miyazaki, Miyazaki 889-1692, Japan.; Project for Advanced Medical Research and Development, Project Research Division, Frontier Science Research Center, University of Miyazaki, Miyazaki 889-1692, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 29; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:: Journal Article
MeSH Terms:: Leukemia-Lymphoma, Adult T-Cell*/pathology
Neoplasms*
Lymphoma*
Intracellular Signaling Peptides and Proteins*
Adult ; Humans ; Protein-Arginine N-Methyltransferases/metabolism ; Adaptor Proteins, Signal Transducing/metabolism ; Arginine/metabolism ; Methylation ; Tumor Suppressor Proteins/metabolism

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Skocz do pozycji: 6.

Tytuł:: The Protein Kinase A Inhibitor KT5720 Prevents Endothelial Dysfunctions Induced by High-Dose Irradiation.
Autorzy:: Boittin FX; Unité de Radiobiologie, Département Effets Biologiques des Rayonnements, IRBA-Institut de Recherche Biomédicale des Armées, Place du Général Valérie André, 91223 Brétigny-sur-Orge, France.
Guitard N; Unité de Radiobiologie, Département Effets Biologiques des Rayonnements, IRBA-Institut de Recherche Biomédicale des Armées, Place du Général Valérie André, 91223 Brétigny-sur-Orge, France.
Toth M; Université Paris-Saclay, INSERM, Laboratory of Signalling and Cardiovascular Pathophysiology U1180, 91400 Orsay, France.
Riccobono D; Unité de Radiobiologie, Département Effets Biologiques des Rayonnements, IRBA-Institut de Recherche Biomédicale des Armées, Place du Général Valérie André, 91223 Brétigny-sur-Orge, France.
Théry H; Unité de Radiobiologie, Département Effets Biologiques des Rayonnements, IRBA-Institut de Recherche Biomédicale des Armées, Place du Général Valérie André, 91223 Brétigny-sur-Orge, France.
Bobe R; Université Paris-Saclay, INSERM, Hémostase Inflammation Thrombose HITh U1176, 94276 Le Kremlin-Bicêtre, France.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 14; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:: Journal Article
MeSH Terms:: Endothelial Cells*/metabolism
Cyclic AMP-Dependent Protein Kinases*/metabolism
Carbazoles*
Pyrroles*
Intracellular Signaling Peptides and Proteins*
Humans ; Cells, Cultured

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Skocz do pozycji: 7.

Tytuł:: The Role of SCAP/SREBP as Central Regulators of Lipid Metabolism in Hepatic Steatosis.
Autorzy:: Chandrasekaran P; UT Southwestern Medical Center Dallas, 5323 Harry Hines Blvd., Dallas, TX 75390, USA.
Weiskirchen R; Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), Rheinisch-Westfälische Technische Hochschule (RWTH) University Hospital Aachen, D-52074 Aachen, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 16; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 16.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Fatty Liver*
Liver Neoplasms*
Sterol Regulatory Element Binding Protein 1*/genetics
Intracellular Signaling Peptides and Proteins*/genetics
Membrane Proteins*/genetics
Animals ; Humans ; Lipid Metabolism ; Lipogenesis

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Skocz do pozycji: 8.

Tytuł:: Erbin accelerates TFEB-mediated lysosome biogenesis and autophagy and alleviates sepsis-induced inflammatory responses and organ injuries.
Autorzy:: Fang Q; The Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuchang, 169 Donghu Road, Wuhan, 430071, Hubei Province, China.
Jing G; The Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuchang, 169 Donghu Road, Wuhan, 430071, Hubei Province, China.
Zhang Y; The Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuchang, 169 Donghu Road, Wuhan, 430071, Hubei Province, China.
Wang H; The Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuchang, 169 Donghu Road, Wuhan, 430071, Hubei Province, China.
Luo H; The Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuchang, 169 Donghu Road, Wuhan, 430071, Hubei Province, China.
Xia Y; The Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuchang, 169 Donghu Road, Wuhan, 430071, Hubei Province, China.
Jin Q; The Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuchang, 169 Donghu Road, Wuhan, 430071, Hubei Province, China.
Liu Y; The Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuchang, 169 Donghu Road, Wuhan, 430071, Hubei Province, China.
Zuo J; The Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuchang, 169 Donghu Road, Wuhan, 430071, Hubei Province, China.
Yang C; The Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuchang, 169 Donghu Road, Wuhan, 430071, Hubei Province, China.
Zhang X; College of Life Sciences at, Wuhan University, Wuchang, 299 Bayi Road, Wuhan, 430072, Hubei Province, China.
Liu S; College of Life Sciences at, Wuhan University, Wuchang, 299 Bayi Road, Wuhan, 430072, Hubei Province, China.
Wu X; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuchang, 238 Liberation Road, Wuhan, 430060, Hubei Province, China. .
Song X; The Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuchang, 169 Donghu Road, Wuhan, 430071, Hubei Province, China. .; Pokaż więcej
Źródło:: Journal of translational medicine [J Transl Med] 2023 Dec 17; Vol. 21 (1), pp. 916. Date of Electronic Publication: 2023 Dec 17.
Typ publikacji:: Journal Article
MeSH Terms:: Cell Nucleus*/metabolism
Sepsis*/complications
Intracellular Signaling Peptides and Proteins*/metabolism
Animals ; Mice ; Autophagosomes/metabolism ; Autophagy/genetics ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/metabolism ; Inflammation/etiology ; Inflammation/genetics ; Inflammation/metabolism ; Lysosomes/genetics ; Lysosomes/metabolism

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Skocz do pozycji: 9.

Tytuł:: Gasdermin D: A Potential New Auxiliary Pan-Biomarker for the Detection and Diagnosis of Diseases.
Autorzy:: Wan N; Department of Clinical Laboratory, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Shi J; Department of Clinical Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Xu J; Department of Clinical Laboratory, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Huang J; Department of Information Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Gan D; Department of Clinical Laboratory, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Tang M; Key Laboratory of Medical Diagnostics Designated by Chinese Ministry of Education, Chongqing Medical University, Chongqing 400016, China.
Li X; Department of Clinical Laboratory, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Huang Y; Department of Clinical Laboratory, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Li P; Department of Clinical Laboratory, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2023 Nov 17; Vol. 13 (11). Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Intracellular Signaling Peptides and Proteins*
Neoplasms*/diagnosis
Humans ; Gasdermins ; Pyroptosis ; Apoptosis

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Skocz do pozycji: 10.

Tytuł:: Expanding the clinical spectrum of cytosolic phosphoenolpyruvate carboxykinase deficiency: novel PCK1 variants in four Arabian Gulf families.
Autorzy:: Al Busaidi M; College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.
Mohamed FE; Genetics and Genomics Department, College of Medicine and Health Sciences, United Arab Emirates University, P. O. Box 1555, Al Ain, United Arab Emirates.; ASPIRE Precision Medicine Research Institute Abu Dhabi, United Arab Emirates University, Al Ain, United Arab Emirates.
Al-Ajmi E; Department of Radiology and Molecular Imaging, Sultan Qaboos University Hospital, Muscat, Oman.
Al Hashmi N; Department of Pediatrics, The Royal Hospital, Muscat, Oman.
Al-Thihli K; Department of Genetic and Developmental Medicine Clinic, Sultan Qaboos University Hospital, P.O. Box 38, Muscat, Alkoudh, 123, Oman.
Al Futaisi A; Department of Child Health, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.
Al Mamari W; Department of Child Health, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.
Al-Murshedi F; Department of Genetic and Developmental Medicine Clinic, Sultan Qaboos University Hospital, P.O. Box 38, Muscat, Alkoudh, 123, Oman. .
Al-Jasmi F; Genetics and Genomics Department, College of Medicine and Health Sciences, United Arab Emirates University, P. O. Box 1555, Al Ain, United Arab Emirates. .; ASPIRE Precision Medicine Research Institute Abu Dhabi, United Arab Emirates University, Al Ain, United Arab Emirates. .; Department of Pediatrics, Tawam Hospital, Al Ain, United Arab Emirates. .; Pokaż więcej
Źródło:: Orphanet journal of rare diseases [Orphanet J Rare Dis] 2023 Nov 03; Vol. 18 (1), pp. 344. Date of Electronic Publication: 2023 Nov 03.
Typ publikacji:: Journal Article
MeSH Terms:: Brain Diseases*
Hypoglycemia*/etiology
Intracellular Signaling Peptides and Proteins*/genetics
Liver Diseases*/complications
Phosphoenolpyruvate Carboxykinase (GTP)*/genetics
Humans ; Infant, Newborn ; Seizures/genetics
SCR Disease Name:: Phosphoenolpyruvate carboxykinase deficiency

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Skocz do pozycji: 11.

Tytuł:: Molecular Mechanism of Mutational Disruption of DCLK1 Autoinhibition Provides a Rationale for Inhibitor Screening.
Autorzy:: Chen W; State Key Laboratory of Microbial Metabolism & Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.
Liu R; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China.
Yu Y; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China.
Wei D; State Key Laboratory of Microbial Metabolism & Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.
Chen Q; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China.
Xu Q; State Key Laboratory of Microbial Metabolism & Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Sep 13; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 13.
Typ publikacji:: Journal Article
MeSH Terms:: Doublecortin-Like Kinases*
Intracellular Signaling Peptides and Proteins*/genetics
Humans ; Protein Serine-Threonine Kinases/metabolism ; Carcinogenesis ; Mutation

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Skocz do pozycji: 12.

Tytuł:: Characterisation of Patients with SH3TC2 Associated Neuropathy in an Indian Cohort.
Autorzy:: Nagappa M; Department of Neurology; Department of Neuromuscular Laboratory, Neurobiology Research Centre (NBRC), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Sharma S; Department of Neurology; Department of Neuropathology; Department of Neuromuscular Laboratory, Neurobiology Research Centre (NBRC), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Govindaraj P; Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, Telangana, India.
Chickabasaviah YT; Department of Neuropathology; Department of Neuromuscular Laboratory, Neurobiology Research Centre (NBRC), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Siram R; Department of Neurology, Neurobiology Research Centre (NBRC), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Shroti A; Department of Neurology, Neurobiology Research Centre (NBRC), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Seshagiri DV; Department of Neurology, Neurobiology Research Centre (NBRC), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Debnath M; Department of Human Genetics, Neurobiology Research Centre (NBRC), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Sinha S; Department of Neurology, Neurobiology Research Centre (NBRC), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Bindu PS; Department of Neurology; Department of Neuromuscular Laboratory, Neurobiology Research Centre (NBRC), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Taly AB; Department of Neurology; Department of Neuromuscular Laboratory, Neurobiology Research Centre (NBRC), National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.; Pokaż więcej
Źródło:: Neurology India [Neurol India] 2023 Sep-Oct; Vol. 71 (5), pp. 940-945.
Typ publikacji:: Journal Article
MeSH Terms:: Intracellular Signaling Peptides and Proteins*/genetics
Charcot-Marie-Tooth Disease*/genetics
Humans ; Female ; Male ; Mutation ; Phenotype ; Electrophysiological Phenomena

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Skocz do pozycji: 13.

Tytuł:: Regulation of TRIB1 abundance in hepatocyte models in response to proteasome inhibition.
Autorzy:: Soubeyrand S; Atherogenomics Laboratory, University of Ottawa Heart Institute, Ottawa, Canada. .
Lau P; Atherogenomics Laboratory, University of Ottawa Heart Institute, Ottawa, Canada.
McPherson R; Atherogenomics Laboratory, University of Ottawa Heart Institute, Ottawa, Canada. .; Division of Cardiology, Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, Ottawa, Canada. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Jun 08; Vol. 13 (1), pp. 9320. Date of Electronic Publication: 2023 Jun 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Intracellular Signaling Peptides and Proteins*/genetics
Intracellular Signaling Peptides and Proteins*/metabolism
Protein Serine-Threonine Kinases*/metabolism
Humans ; Hepatocytes/metabolism ; Proteasome Endopeptidase Complex/metabolism ; Proteasome Inhibitors/pharmacology ; Proteasome Inhibitors/metabolism ; RNA, Messenger/genetics

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Skocz do pozycji: 14.

Tytuł:: DNA damage-induced cellular senescence is regulated by 53BP1 accumulation in the nuclear foci and phase separation.
Autorzy:: Oda T; Laboratory of Mucosal Ecosystem Design, The Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Gunma, Japan.
Gotoh N; Graduate School of Health Sciences, Gunma University, Maebashi, Gunma, Japan.
Kasamatsu T; Graduate School of Health Sciences, Gunma University, Maebashi, Gunma, Japan.
Handa H; Graduate School of Medicine, Gunma University, Maebashi, Gunma, Japan.
Saitoh T; Graduate School of Health Sciences, Gunma University, Maebashi, Gunma, Japan.
Sasaki N; Laboratory of Mucosal Ecosystem Design, The Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Gunma, Japan.; Pokaż więcej
Źródło:: Cell proliferation [Cell Prolif] 2023 Jun; Vol. 56 (6), pp. e13398. Date of Electronic Publication: 2023 Jan 15.
Typ publikacji:: Journal Article
MeSH Terms:: Intracellular Signaling Peptides and Proteins*/genetics
Intracellular Signaling Peptides and Proteins*/metabolism
Tumor Suppressor Protein p53*/metabolism
Humans ; Cell Nucleus/metabolism ; Cellular Senescence ; DNA Damage ; DNA Repair ; Tumor Suppressor p53-Binding Protein 1/genetics ; Tumor Suppressor p53-Binding Protein 1/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism

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Skocz do pozycji: 15.

Tytuł:: DCUN1D1 Is an Essential Regulator of Prostate Cancer Proliferation and Tumour Growth That Acts through Neddylation of Cullin 1, 3, 4A and 5 and Deregulation of Wnt/Catenin Pathway.
Autorzy:: Vava A; Cancer Genomics Group, International Centre for Genetic Engineering and Biotechnology, Cape Town 7925, South Africa.; Division of Chemical and Systems Biology, Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town 7925, South Africa.
Paccez JD; Cancer Genomics Group, International Centre for Genetic Engineering and Biotechnology, Cape Town 7925, South Africa.
Wang Y; Department of Pathology and Laboratory Medicine, Warren Alpert School of Medicine, Brown University, Providence, RI 02912, USA.
Gu X; BIDMC Genomics, Proteomics, Bioinformatics and Systems Biology Center, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
Bhasin MK; Department of Pediatrics Bioinformatics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Myers M; Protein Networks Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), 34149 Trieste, Italy.
Soares NC; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah P.O. Box 26666, United Arab Emirates.; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah P.O. Box 26666, United Arab Emirates.; Laboratory of Proteomics, Department of Human Genetics, National Institute of Health, Doutor Ricardo Jorge (INSA), 1649-016 Lisbon, Portugal.; Centre for Toxicogenomics and Human Health (ToxOmics), NOVA/School/Faculdade de Lisboa, 1169-056 Lisbon, Portugal.
Libermann TA; BIDMC Genomics, Proteomics, Bioinformatics and Systems Biology Center, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
Zerbini LF; Cancer Genomics Group, International Centre for Genetic Engineering and Biotechnology, Cape Town 7925, South Africa.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Jul 31; Vol. 12 (15). Date of Electronic Publication: 2023 Jul 31.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Cullin Proteins*/metabolism
Intracellular Signaling Peptides and Proteins*/metabolism
Prostatic Neoplasms*/genetics
Animals ; Humans ; Male ; Mice ; beta Catenin ; Catenins ; Cell Proliferation ; Proto-Oncogene Proteins/metabolism ; Wnt Signaling Pathway

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Skocz do pozycji: 16.

Tytuł:: Dabie bandavirus infection induces macrophagic pyroptosis and this process is attenuated by platelets.
Autorzy:: Yu S; Department of Critical Care Medicine, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, China.; The First People's Hospital of Xiaoshan District, Hangzhou, China.
Zhang Q; School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, China.; Department of Microbiology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Su L; Department of Microbiology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
He J; Blood Center of Zhejiang Province, Hangzhou, China.
Shi W; Department of Microbiology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Yan H; Department of Microbiology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Mao H; Department of Microbiology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Sun Y; Department of Microbiology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Cheng D; School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, China.
Wang X; Shaoxing Shangyu District Center for Disease Control and Prevention, Shaoxing, China.
Zhang Y; Department of Microbiology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Fang L; Department of Critical Care Medicine, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou, China.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Jul 24; Vol. 17 (7), pp. e0011488. Date of Electronic Publication: 2023 Jul 24 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Intracellular Signaling Peptides and Proteins*/metabolism
Severe Fever with Thrombocytopenia Syndrome*
Humans ; Blood Platelets ; Pyroptosis ; Macrophages/metabolism

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Skocz do pozycji: 17.

Tytuł:: A Novel Small NPC1 Promoter Enhances AAV-Mediated Gene Therapy in Mouse Models of Niemann-Pick Type C1 Disease.
Autorzy:: Hughes MP; UCL School of Pharmacy, University College London, London WC1N 1AX, UK.
Nelvagal HR; UCL School of Pharmacy, University College London, London WC1N 1AX, UK.
Coombe-Tennant O; UCL School of Pharmacy, University College London, London WC1N 1AX, UK.
Smith D; Department of Pharmacology, University of Oxford, Oxford OX1 3QT, UK.
Smith C; Department of Pharmacology, University of Oxford, Oxford OX1 3QT, UK.
Massaro G; UCL School of Pharmacy, University College London, London WC1N 1AX, UK.
Poupon-Bejuit L; UCL School of Pharmacy, University College London, London WC1N 1AX, UK.
Platt FM; Department of Pharmacology, University of Oxford, Oxford OX1 3QT, UK.
Rahim AA; UCL School of Pharmacy, University College London, London WC1N 1AX, UK.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Jun 13; Vol. 12 (12). Date of Electronic Publication: 2023 Jun 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Therapy*/methods
Intracellular Signaling Peptides and Proteins*/metabolism
Niemann-Pick C1 Protein*/genetics
Niemann-Pick Disease, Type C*/genetics
Niemann-Pick Disease, Type C*/therapy
Niemann-Pick Disease, Type C*/metabolism
Animals ; Mice ; Mutation ; Genetic Vectors ; Promoter Regions, Genetic/genetics

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Skocz do pozycji: 18.

Tytuł:: The WASH-complex subunit Strumpellin regulates integrin αIIbβ3 trafficking in murine platelets.
Autorzy:: Schurr Y; Institute of Experimental Biomedicine-Chair I, University Hospital and Rudolf Virchow Center, Josef-Schneider-Str. 2, 97080, Würzburg, Germany.
Reil L; Institute of Experimental Biomedicine-Chair I, University Hospital and Rudolf Virchow Center, Josef-Schneider-Str. 2, 97080, Würzburg, Germany.
Spindler M; Institute of Experimental Biomedicine-Chair I, University Hospital and Rudolf Virchow Center, Josef-Schneider-Str. 2, 97080, Würzburg, Germany.
Nieswandt B; Institute of Experimental Biomedicine-Chair I, University Hospital and Rudolf Virchow Center, Josef-Schneider-Str. 2, 97080, Würzburg, Germany.
Machesky LM; Department of Biochemistry, University of Cambridge, Sanger Building, 80 Tennis Court Road, Cambridge, CB2 1GA, UK.
Bender M; Institute of Experimental Biomedicine-Chair I, University Hospital and Rudolf Virchow Center, Josef-Schneider-Str. 2, 97080, Würzburg, Germany. Bender_.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Jun 12; Vol. 13 (1), pp. 9526. Date of Electronic Publication: 2023 Jun 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Integrin alpha2*/metabolism
Integrin beta3*/metabolism
Intracellular Signaling Peptides and Proteins*/metabolism
Animals ; Mice ; Blood Platelets/metabolism ; Megakaryocytes/metabolism ; Mice, Knockout

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Skocz do pozycji: 19.

Tytuł:: Stability Determination of Intact Humanin-G with Characterizations of Oxidation and Dimerization Patterns.
Autorzy:: Ozgul M; Department of Ophthalmology, Gavin Herbert Eye Institute, University of California Irvine, Irvine, CA 92617, USA.
Nesburn AB; Department of Ophthalmology, Gavin Herbert Eye Institute, University of California Irvine, Irvine, CA 92617, USA.; Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Nasralla N; IVD Technologies Inc., Santa Ana, CA 92705, USA.
Katz B; Department of Chemistry, University of California Irvine, Irvine, CA 92697, USA.
Taylan E; Department of Obstetrics and Gynecology, University of California Los Angeles, Los Angeles, CA 90095, USA.
Kuppermann BD; Department of Ophthalmology, Gavin Herbert Eye Institute, University of California Irvine, Irvine, CA 92617, USA.
Kenney MC; Department of Ophthalmology, Gavin Herbert Eye Institute, University of California Irvine, Irvine, CA 92617, USA.; Department of Pathology and Laboratory Medicine, University of California Irvine, Irvine, CA 92617, USA.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2023 Mar 11; Vol. 13 (3). Date of Electronic Publication: 2023 Mar 11.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Intracellular Signaling Peptides and Proteins*
Peptides*
Humans ; Dimerization

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Skocz do pozycji: 20.

Tytuł:: Oscillation of Autophagy Induction under Cellular Stress and What Lies behind It, a Systems Biology Study.
Autorzy:: Hajdú B; Department of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis University, 1085 Budapest, Hungary.
Csabai L; Earlham Institute, Norwich Research Park, Norwich NR4 7UG, UK.; Department of Genetics, Eötvös Loránd University, 1117 Budapest, Hungary.
Márton M; Department of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis University, 1085 Budapest, Hungary.
Holczer M; Department of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis University, 1085 Budapest, Hungary.
Korcsmáros T; Earlham Institute, Norwich Research Park, Norwich NR4 7UG, UK.; Department of Genetics, Eötvös Loránd University, 1117 Budapest, Hungary.; Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, UK.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London W12 0NN, UK.
Kapuy O; Department of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis University, 1085 Budapest, Hungary.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 21; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 21.
Typ publikacji:: Journal Article
MeSH Terms:: AMP-Activated Protein Kinases*/metabolism
Intracellular Signaling Peptides and Proteins*/pharmacology
Autophagy-Related Protein-1 Homolog/genetics ; Autophagy-Related Protein-1 Homolog/metabolism ; Systems Biology ; TOR Serine-Threonine Kinases/metabolism ; Autophagy

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