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Wyszukujesz frazę ""Perl, M."" wg kryterium: Autor


Tytuł :
Role of Complement C5 in Experimental Blunt Chest Trauma-Induced Septic Acute Lung Injury (ALI).
Autorzy :
Kalbitz M; Department of Traumatology, Hand-, Plastic-, and Reconstructive Surgery, Center of Surgery, University of Ulm, Ulm, Germany.
Karbach M; Department of Traumatology, Hand-, Plastic-, and Reconstructive Surgery, Center of Surgery, University of Ulm, Ulm, Germany.
Braumueller S; Department of Traumatology, Hand-, Plastic-, and Reconstructive Surgery, Center of Surgery, University of Ulm, Ulm, Germany.
Kellermann P; Department of Traumatology, Hand-, Plastic-, and Reconstructive Surgery, Center of Surgery, University of Ulm, Ulm, Germany.
Gebhard F; Department of Traumatology, Hand-, Plastic-, and Reconstructive Surgery, Center of Surgery, University of Ulm, Ulm, Germany.
Huber-Lang M; Department of Traumatology, Hand-, Plastic-, and Reconstructive Surgery, Center of Surgery, University of Ulm, Ulm, Germany.
Perl M; Department of Traumatology, Hand-, Plastic-, and Reconstructive Surgery, Center of Surgery, University of Ulm, Ulm, Germany.; Orthopedic Trauma, BG-Trauma Center Murnau, Murnau, Germany.
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Źródło :
PloS one [PLoS One] 2016 Jul 20; Vol. 11 (7), pp. e0159417. Date of Electronic Publication: 2016 Jul 20 (Print Publication: 2016).
Typ publikacji :
Journal Article
Journal Info :
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS ONE Subsets: MEDLINE
MeSH Terms :
Acute Lung Injury/*genetics
Complement C5/*genetics
Inflammation/*genetics
Respiratory Distress Syndrome, Adult/*genetics
Sepsis/*genetics
Acute Lung Injury/pathology ; Animals ; Caspase 3/biosynthesis ; Chemokine CCL2/biosynthesis ; Complement C5/metabolism ; Granulocyte Colony-Stimulating Factor/biosynthesis ; Humans ; Inflammation/complications ; Inflammation/pathology ; Interleukin-6/biosynthesis ; Mice ; Respiratory Distress Syndrome, Adult/pathology ; Risk Factors ; Sepsis/blood ; Sepsis/complications ; Sepsis/pathology ; Thoracic Injuries/genetics ; Thoracic Injuries/pathology ; Wounds, Nonpenetrating/genetics
Czasopismo naukowe
Tytuł :
Apoptotic and inflammatory signaling via Fas and tumor necrosis factor receptor I contribute to the development of chest trauma-induced septic acute lung injury.
Autorzy :
Weckbach S; Department of Trauma, University of Ulm, Ulm, Germany.
Hohmann C
Denk S
Kellermann P
Huber-Lang MS
Baumann B
Wirth T
Gebhard F
Bachem M
Perl M
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Źródło :
The journal of trauma and acute care surgery [J Trauma Acute Care Surg] 2013 Mar; Vol. 74 (3), pp. 792-800.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Lippincott, Williams & Wilkins Country of Publication: United States NLM ID: 101570622 Publication Model: Print Cited Medium: Internet ISSN: 2163-0763 (Electronic) Linking ISSN: 21630755 NLM ISO Abbreviation: J Trauma Acute Care Surg Subsets: Core Clinical (AIM); MEDLINE
MeSH Terms :
Apoptosis*
Acute Lung Injury/*etiology
Bronchoalveolar Lavage Fluid/*chemistry
Receptors, Tumor Necrosis Factor, Type I/*metabolism
Sepsis/*complications
Thoracic Injuries/*complications
fas Receptor/*metabolism
Acute Lung Injury/metabolism ; Acute Lung Injury/pathology ; Animals ; Disease Models, Animal ; Enzyme-Linked Immunosorbent Assay ; In Situ Nick-End Labeling ; Male ; Mice ; Mice, Inbred C57BL ; Sepsis/metabolism ; Sepsis/pathology ; Signal Transduction ; Thoracic Injuries/metabolism ; Thoracic Injuries/pathology
Czasopismo naukowe
Tytuł :
Role of activated neutrophils in chest trauma-induced septic acute lung injury.
Autorzy :
Perl M; Department of Trauma, Hand, Plastic, and Reconstructive Surgery, University of Ulm, Ulm, Germany. mario.perl@uniklinik-ulm.de
Hohmann C
Denk S
Kellermann P
Lu D
Braumüller S
Bachem MG
Thomas J
Knöferl MW
Ayala A
Gebhard F
Huber-Lang MS
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Źródło :
Shock (Augusta, Ga.) [Shock] 2012 Jul; Vol. 38 (1), pp. 98-106.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9421564 Publication Model: Print Cited Medium: Internet ISSN: 1540-0514 (Electronic) Linking ISSN: 10732322 NLM ISO Abbreviation: Shock Subsets: MEDLINE
MeSH Terms :
Acute Lung Injury/*etiology
Neutrophil Activation/*immunology
Neutrophils/*immunology
Sepsis/*complications
Thoracic Injuries/*complications
Acute Lung Injury/immunology ; Acute Lung Injury/pathology ; Animals ; Apoptosis/immunology ; Bronchoalveolar Lavage Fluid/chemistry ; Carbon Dioxide/blood ; Caspases/metabolism ; Chemokines/blood ; Cytokines/blood ; Disease Models, Animal ; Lung/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Oxygen/blood ; Partial Pressure ; Sepsis/immunology ; Systemic Inflammatory Response Syndrome/etiology ; Systemic Inflammatory Response Syndrome/immunology ; Wounds, Nonpenetrating/complications ; fas Receptor/blood
Czasopismo naukowe
Tytuł :
The role and source of tumor necrosis factor-α in hemorrhage-induced priming for septic lung injury.
Autorzy :
Lomas-Neira J; Division of Surgical Research, Department of Surgery, Rhode Island Hospital/Alpert School of Medicine at Brown University, Providence, Rhode Island 02903, USA.
Perl M
Venet F
Chung CS
Ayala A
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Źródło :
Shock (Augusta, Ga.) [Shock] 2012 Jun; Vol. 37 (6), pp. 611-20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9421564 Publication Model: Print Cited Medium: Internet ISSN: 1540-0514 (Electronic) Linking ISSN: 10732322 NLM ISO Abbreviation: Shock Subsets: MEDLINE
MeSH Terms :
Acute Lung Injury/*physiopathology
Sepsis/*complications
Shock, Hemorrhagic/*complications
Tumor Necrosis Factor-alpha/*physiology
Acute Lung Injury/etiology ; Acute Lung Injury/metabolism ; Adoptive Transfer ; Animals ; Lung/metabolism ; Lung/pathology ; Male ; Mice ; Mice, Knockout ; Mice, Transgenic ; Neutrophils/pathology ; Neutrophils/transplantation ; RNA, Small Interfering/administration & dosage ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Damage- and pathogen-associated molecular patterns and alarmins: keys to sepsis?.
Autorzy :
Denk S; Department of Traumatology, Hand, Plastic and Reconstructive Surgery, University of Ulm, Ulm, Germany.
Perl M
Huber-Lang M
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Źródło :
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes [Eur Surg Res] 2012; Vol. 48 (4), pp. 171-9. Date of Electronic Publication: 2012 May 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
Journal Info :
Publisher: Karger Country of Publication: Switzerland NLM ID: 0174752 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9921 (Electronic) Linking ISSN: 0014312X NLM ISO Abbreviation: Eur Surg Res Subsets: MEDLINE
MeSH Terms :
Sepsis/*immunology
Animals ; Bacteria/pathogenicity ; DNA/physiology ; Fungi/pathogenicity ; HMGB1 Protein/physiology ; Histones/physiology ; Humans ; Immunity, Innate ; Mitochondria/physiology ; Nuclear Proteins/physiology ; Viruses/pathogenicity
Czasopismo naukowe
Tytuł :
Hydrodynamic delivery of siRNA in a mouse model of sepsis.
Autorzy :
Wesche-Soldato DE; Department of Surgery, Rhode Island Hospital/Brown University School of Medicine, Division of Surgical Research, Providence, RI, USA.
Lomas-Neira J
Perl M
Chung CS
Ayala A
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2008; Vol. 442, pp. 67-73.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Print ISSN: 1064-3745 (Print) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol. Biol. Subsets: MEDLINE
MeSH Terms :
Gene Transfer Techniques*
Genetic Therapy/*methods
RNA, Small Interfering/*metabolism
Sepsis/*therapy
Animals ; Disease Models, Animal ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; RNA, Small Interfering/genetics
Czasopismo naukowe
Tytuł :
Apoptosis in sepsis: mechanisms, clinical impact and potential therapeutic targets.
Autorzy :
Ayala A; Division of Surgical Research, Department of Surgery, Rhode Island Hospital/Brown University School of Medicine, Providence, RI 02903, USA. />Perl M
Venet F
Lomas-Neira J
Swan R
Chung CS
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Źródło :
Current pharmaceutical design [Curr Pharm Des] 2008; Vol. 14 (19), pp. 1853-9.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
Journal Info :
Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9602487 Publication Model: Print Cited Medium: Internet ISSN: 1873-4286 (Electronic) Linking ISSN: 13816128 NLM ISO Abbreviation: Curr. Pharm. Des. Subsets: MEDLINE
MeSH Terms :
Apoptosis/*drug effects
Multiple Organ Failure/*physiopathology
Sepsis/*physiopathology
Animals ; Critical Illness ; Drug Delivery Systems ; Humans ; Multiple Organ Failure/drug therapy ; Multiple Organ Failure/etiology ; Necrosis/metabolism ; Rodentia ; Sepsis/complications ; Sepsis/drug therapy ; Signal Transduction
Czasopismo naukowe
Tytuł :
Polymicrobial sepsis enhances clearance of apoptotic immune cells by splenic macrophages.
Autorzy :
Swan R; Division of Surgical Research, Department of Surgery, Brown University School of Medicine, Providence, RI, USA.
Chung CS
Albina J
Cioffi W
Perl M
Ayala A
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Źródło :
Surgery [Surgery] 2007 Aug; Vol. 142 (2), pp. 253-61.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Mosby Country of Publication: United States NLM ID: 0417347 Publication Model: Print Cited Medium: Print ISSN: 0039-6060 (Print) Linking ISSN: 00396060 NLM ISO Abbreviation: Surgery Subsets: Core Clinical (AIM); MEDLINE
MeSH Terms :
Apoptosis/*immunology
Macrophages, Peritoneal/*immunology
Phagocytosis/*immunology
Sepsis/*immunology
T-Lymphocytes/*immunology
Animals ; Cecum/injuries ; Cecum/microbiology ; Flow Cytometry ; Fluoresceins ; Fluorescent Dyes ; Ligation ; Macrophages, Peritoneal/cytology ; Male ; Mice ; Mice, Inbred C57BL ; Spleen/cytology ; Spleen/immunology ; Succinimides ; T-Lymphocytes/cytology ; Wounds, Stab
Czasopismo naukowe
Tytuł :
Blockade of apoptosis as a rational therapeutic strategy for the treatment of sepsis.
Autorzy :
Ayala A; Shock-Trauma Research Laboratory, Division of Surgical Research, Department of Surgery, Rhode Island Hospital / Brown University School of Medicine, Providence, RI 02903, USA.
Wesche-Soldato DE
Perl M
Lomas-Neira JL
Swan R
Chung CS
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Źródło :
Novartis Foundation symposium [Novartis Found Symp] 2007; Vol. 280, pp. 37-49; discussion 49-52, 160-4.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review
Journal Info :
Publisher: Wiley Country of Publication: England NLM ID: 9807767 Publication Model: Print Cited Medium: Print ISSN: 1528-2511 (Print) Linking ISSN: 15282511 NLM ISO Abbreviation: Novartis Found. Symp. Subsets: MEDLINE
MeSH Terms :
Apoptosis*
Sepsis/*therapy
Animals ; Humans ; Sepsis/metabolism ; Sepsis/pathology ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Role of alveolar macrophage and migrating neutrophils in hemorrhage-induced priming for ALI subsequent to septic challenge.
Autorzy :
Lomas-Neira J; Department of Cell and Molecular Biology, University of Rhode Island, Kingston, USA.
Chung CS
Perl M
Gregory S
Biffl W
Ayala A
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2006 Jan; Vol. 290 (1), pp. L51-8. Date of Electronic Publication: 2005 Sep 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1040-0605 (Print) Linking ISSN: 10400605 NLM ISO Abbreviation: Am. J. Physiol. Lung Cell Mol. Physiol. Subsets: MEDLINE
MeSH Terms :
Macrophages, Alveolar*/pathology
Neutrophil Infiltration*
Hemorrhage/*complications
Hemorrhage/*physiopathology
Lung Diseases/*etiology
Sepsis/*complications
Acute Disease ; Animals ; Bronchoalveolar Lavage Fluid/chemistry ; Chemokines/antagonists & inhibitors ; Endothelial Cells/metabolism ; Esterases/metabolism ; Hemorrhage/pathology ; Intercellular Adhesion Molecule-1/metabolism ; Interleukin-10/metabolism ; Lung/enzymology ; Lung/metabolism ; Male ; Mice ; Mice, Inbred C3H ; Neutropenia/metabolism ; Neutropenia/physiopathology ; Neutrophils/enzymology ; Peroxidase/metabolism ; Pneumonia/prevention & control ; Proteins/metabolism ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Contribution of anti-inflammatory/immune suppressive processes to the pathology of sepsis.
Autorzy :
Perl M; Division of Surgical Research, Department of Surgery, RI Hospital, Brown University School of Medicine, Providence, RI 02903, USA.
Chung CS
Garber M
Huang X
Ayala A
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Źródło :
Frontiers in bioscience : a journal and virtual library [Front Biosci] 2006 Jan 01; Vol. 11, pp. 272-99. Date of Electronic Publication: 2006 Jan 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review
Journal Info :
Publisher: Frontiers In Bioscience Publications Country of Publication: United States NLM ID: 9709506 Publication Model: Electronic Cited Medium: Internet ISSN: 1093-9946 (Print) Linking ISSN: 10934715 NLM ISO Abbreviation: Front. Biosci. Subsets: MEDLINE
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Sepsis/*immunology
Sepsis/*pathology
Animals ; Antigens, CD ; Antigens, Differentiation/metabolism ; Apoptosis ; CTLA-4 Antigen ; Down-Regulation ; Humans ; Immune System/pathology ; Immune System Diseases/pathology ; Inflammation ; Intercellular Adhesion Molecule-1/metabolism ; Lymphocytes/metabolism ; Macrophages/metabolism ; Mice ; Models, Biological ; NF-kappa B/metabolism ; Neutrophils/metabolism ; Nitric Oxide/metabolism ; Prostaglandins/metabolism
Czasopismo naukowe
Tytuł :
Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis.
Autorzy :
Perl M; Shock-Trauma Research Laboratories, Division of Surgical Research, Providence, RI 02903, USA.
Chung CS
Lomas-Neira J
Rachel TM
Biffl WL
Cioffi WG
Ayala A
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Źródło :
The American journal of pathology [Am J Pathol] 2005 Dec; Vol. 167 (6), pp. 1545-59.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Elsevier Country of Publication: United States NLM ID: 0370502 Publication Model: Print Cited Medium: Print ISSN: 0002-9440 (Print) Linking ISSN: 00029440 NLM ISO Abbreviation: Am. J. Pathol. Subsets: Core Clinical (AIM); MEDLINE
MeSH Terms :
Gene Silencing*
Caspases/*genetics
Lung Diseases/*genetics
Neutrophils/*physiology
Sepsis/*genetics
Shock, Hemorrhagic/*genetics
fas Receptor/*genetics
Animals ; Apoptosis ; Base Sequence ; Caspase 8 ; DNA Primers ; Disease Models, Animal ; Inflammation ; Lung Diseases/pathology ; Lung Injury ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; RNA, Small Interfering/genetics ; Sepsis/pathology ; Sepsis/therapy ; Shock, Hemorrhagic/pathology ; Shock, Hemorrhagic/therapy
Czasopismo naukowe
Tytuł :
Pulmonary contusion causes impairment of macrophage and lymphocyte immune functions and increases mortality associated with a subsequent septic challenge.
Autorzy :
Perl M; Department of Trauma, Hand, and Reconstructive Surgery, University of Ulm, Germany.
Gebhard F
Brückner UB
Ayala A
Braumüller S
Büttner C
Kinzl L
Knöferl MW
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Źródło :
Critical care medicine [Crit Care Med] 2005 Jun; Vol. 33 (6), pp. 1351-8.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0355501 Publication Model: Print Cited Medium: Print ISSN: 0090-3493 (Print) Linking ISSN: 00903493 NLM ISO Abbreviation: Crit. Care Med. Subsets: Core Clinical (AIM); MEDLINE
MeSH Terms :
Immune Tolerance*
Lung Injury*
Contusions/*immunology
Leukocytes, Mononuclear/*immunology
Macrophages/*immunology
Sepsis/*immunology
Analysis of Variance ; Animals ; Cells, Cultured ; Contusions/mortality ; Contusions/physiopathology ; Cytokines/metabolism ; Interleukin-6/blood ; Macrophages, Peritoneal/immunology ; Male ; Mice ; Mice, Inbred C3H ; Random Allocation ; Sepsis/mortality ; Spleen/cytology ; Spleen/immunology ; Survival Analysis ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
The role and regulation of apoptosis in sepsis.
Autorzy :
Wesche-Soldato DE; Division of Surgical Research, Department of Surgery, RI Hospital/Brown University School of Medicine, Providence, Rhode Island, USA.
Lomas-Neira JL
Perl M
Jones L
Chung CS
Ayala A
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Źródło :
Journal of endotoxin research [J Endotoxin Res] 2005; Vol. 11 (6), pp. 375-82.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
Journal Info :
Publisher: Sage Publications Country of Publication: United States NLM ID: 9433350 Publication Model: Print Cited Medium: Print ISSN: 0968-0519 (Print) Linking ISSN: 09680519 NLM ISO Abbreviation: J. Endotoxin Res. Subsets: MEDLINE
MeSH Terms :
Apoptosis*
Sepsis*
Animals ; Humans ; Models, Biological
Czasopismo naukowe

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