- Tytuł:
- Accumulation of dipeptide repeat proteins predates that of TDP-43 in frontotemporal lobar degeneration associated with hexanucleotide repeat expansions in C9ORF72 gene.
- Autorzy:
- Źródło:
- Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2015 Aug; Vol. 41 (5), pp. 601-12. Date of Electronic Publication: 2015 Apr 30.
- Typ publikacji:
- Case Reports; Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Brain /*metabolism
DNA-Binding Proteins/*metabolism
Dipeptides/*metabolism
Frontotemporal Lobar Degeneration/*metabolism
Proteins/*genetics
Aged ;Brain /pathology ; C9orf72 Protein ; DNA Repeat Expansion ; Female ; Frontotemporal Lobar Degeneration/genetics ; Frontotemporal Lobar Degeneration/pathology ; Humans ; Inclusion Bodies/metabolism ; Inclusion Bodies/pathology ; Male ; Middle Aged ; Neurons/metabolism ; Neurons/pathology
Czasopismo naukowe